CN115737473A - Skin cream containing pawpaw extract and preparation method thereof - Google Patents

Skin cream containing pawpaw extract and preparation method thereof Download PDF

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Publication number
CN115737473A
CN115737473A CN202211681263.4A CN202211681263A CN115737473A CN 115737473 A CN115737473 A CN 115737473A CN 202211681263 A CN202211681263 A CN 202211681263A CN 115737473 A CN115737473 A CN 115737473A
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China
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percent
stirring
mixture
skin
rmp
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CN202211681263.4A
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Chinese (zh)
Inventor
胡小玉
杨帅
张建鑫
刘剑飞
李者祥
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Henan Huibo Medical Co ltd
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Henan Huibo Medical Co ltd
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Priority to CN202211681263.4A priority Critical patent/CN115737473A/en
Publication of CN115737473A publication Critical patent/CN115737473A/en
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Abstract

The invention relates to a skin cream containing papaya extract and a preparation method thereof, belonging to the technical field of skin care products. The skin cream containing the pawpaw extract comprises the following components in percentage by mass: 2 to 4 percent of papain, 1 to 2 percent of emulsifier, 0.6 to 1 percent of tocopherol acetate, 0.2 to 0.5 percent of thickening agent, 0.1 to 0.2 percent of triethanolamine, 0.03 to 0.05 percent of EDTA-disodium, 0.2 to 0.3 percent of humectant, 1.2 to 1.8 percent of mussel mucin, 1.8 to 2.4 percent of collagen, 2 to 3 percent of glycerol and the balance of water. The skin cream containing fructus Chaenomelis extract has effects of enhancing skin cell activity, inhibiting melanin generation, rapidly absorbing components by skin, enhancing skin metabolism rate, reducing skin problems, and relieving skin aging.

Description

Skin cream containing pawpaw extract and preparation method thereof
Technical Field
The invention belongs to the technical field of comprehensive development and utilization of plant natural products, and particularly relates to a papaya extract-containing skin cream and a preparation method thereof.
Background
The pawpaw is rich in various vitamin mineral substances, active enzymes, proteins and the like, researches show that finished products contained in the pawpaw can invigorate spleen, promote digestion, relax bowels, check diarrhea, maintain beauty, keep young, promote lactation, resist cancer, supplement partial nutrient substances required by a human body and improve the immunity of the human body, and the contained papain has specificity, can decompose the proteins in acidic and alkaline environments, is widely applied to medicines, cosmetics and foods and is safe and effective protease. The papain is derived from fresh milk of immature papaya fruits, is an incision enzyme containing a sulfhydryl peptide chain, has the activities of protease and esterase, has wider specificity, and has stronger hydrolytic capability on animal and plant proteins, polypeptides, esters, amides and the like; at the same time, the protein hydrolysate can be synthesized into protein-like products. The papain can hydrolyze proteins such as gelatin, hide glue and the like in cosmetics into small molecular polypeptides, is easy to be absorbed by skin, and can achieve the effect of beautifying the skin; on the other hand, the medical papain can help digestion, remove ulcer, rotten tissue and the like, and can be mixed with other medicinal components for treatment.
The invention patent with application publication number CN107638370A discloses a skin care product for whitening and removing freckles, which comprises the following components by mass percent, 0.1-5% of pawpaw stem cell extract, 0.5-6% of lemon extract, 0.5-8% of angelica sinensis extract and 0.8-6% of platycodon grandiflorum extract. The water-based cleaning agent also comprises the following components, by mass, 5-10% of esters, 5-8% of oils, 0.1-0.4% of thickening agents, 15-20% of humectants, 2-8% of emulsifiers, 0.1-1.0% of preservatives, 0.1-0.4% of triethanolamine, 0.1-1.0% of essence and the balance of deionized water. The skin care product has single skin care effect on skin, has timeliness, cannot fundamentally solve the skin problem, and has side effects of different degrees.
Disclosure of Invention
The invention aims to provide a skin cream containing papaya extract, which aims to solve the technical problems that a skin care product has a single skin care effect on skin, is time-efficient and has side effects of different degrees.
The invention also aims to provide a preparation method of the skin cream containing the pawpaw extract.
In order to achieve the above purpose, the invention adopts the technical scheme that:
a skin cream containing papaya extract comprises the following components in percentage by mass: 2 to 4 percent of papain, 1 to 2 percent of emulsifier, 0.6 to 1 percent of tocopherol acetate, 0.2 to 0.5 percent of thickening agent, 0.1 to 0.2 percent of triethanolamine, 0.03 to 0.05 percent of EDTA-disodium, 0.2 to 0.3 percent of humectant, 1.2 to 1.8 percent of mussel mucin, 1.8 to 2.4 percent of collagen, 2 to 3 percent of glycerol and the balance of water.
Further, the thickener is carbomer or hydroxyethyl cellulose.
Further, the humectant is one or more of sodium hyaluronate, 1, 2-pentanediol and 1, 2-hexanediol.
Further, the emulsifier is shea butter.
A preparation method of a skin cream containing pawpaw extract comprises the following steps:
1) Mixing the thickener with the amount of 50-60% of the water in the formula, uniformly stirring, adding the glycerin and the EDTA-disodium in the formula, and uniformly stirring to obtain gel A;
2) Heating, stirring and dissolving the emulsifier and the tocopherol acetate in the formula amount, then adding the mixture into the gel A, heating and stirring the mixture until the mixture is uniform and has no particles, and then adding triethanolamine and stirring the mixture uniformly to obtain gel B;
3) Mixing the papain, the humectant, the mussel mucin, the collagen and the residual water according to the formula ratio, stirring uniformly, adding the mixture into the B gel, and stirring uniformly to obtain the skin care product.
Further, the thickener in the formula amount is mixed with water in the step 1) and stirred at the temperature of 60-65 ℃ and the rotating speed of 60-70 rmp; after the glycerol and the EDTA-disodium with the formula amount are added, the mixture is stirred at the temperature of 60-65 ℃ and the rotating speed of 60-70 rmp.
Further, in the step 2), the emulsifier and the tocopherol acetate in the formula amount are heated, stirred and dissolved at the temperature of 60-65 ℃ and the rotating speed of 60-70 rmp; adding the mixture into the A gel, heating and stirring the mixture at the temperature of between 60 and 65 ℃, and stirring the mixture for 30 to 40min at the rotating speed of between 60 and 70 rmp.
Further, in the step 3), the papain, the humectant, the mussel mucin, the collagen and the residual water in the formula amount are mixed and stirred uniformly at 60-70 rmp for 30-40 min, and then added into the gel B and stirred uniformly at 60-70 rmp for 30-40 min.
The invention has the beneficial effects that:
the skin cream containing the pawpaw extract can reduce the acne phenomenon caused by endocrine dyscrasia by the contained papain, and has the functions of diminishing inflammation and relieving pain; mussel mucin can inhibit melanin generation and resist oxidation; the collagen is rich in various amino acids, and can promote skin metabolism and moisten skin; papain, mussel mucin, collagen, tocopherol acetate and sodium hyaluronate act synergistically, carbomer, triethanolamine and the like are used as auxiliaries, the activity of skin cells is enhanced, the generation of melanin is inhibited, the contained components can be quickly absorbed by the skin, the skin metabolism rate is enhanced, the skin problem is reduced, and the skin aging is relieved.
Detailed Description
The present invention will be further described with reference to the following examples.
Example 1
The skin cream containing the papaya extract in the embodiment contains the following components in percentage by mass: 4% of papain, 2% of shea butter, 1% of tocopherol acetate, 0.5% of carbomer, 0.2% of triethanolamine, 0.05% of EDTA-disodium, 0.3% of sodium hyaluronate, 1.8% of mussel mucin, 2.4% of collagen, 3.0% of glycerol and the balance of purified water.
The preparation method of the skin cream containing the papaya extract comprises the following steps:
1) Mixing carbomer with a formula amount and 60% of water, stirring at 60 deg.C and 60rmp to obtain uniform state, adding glycerol and EDTA-disodium with a formula amount, and stirring at 60 deg.C and 60rmp to obtain gel A;
2) Heating, stirring and dissolving shea butter and tocopherol acetate according to the formula amount at 65 ℃ and 70rmp rotating speed, then adding the mixture into the gel A at 65 ℃ and 70rmp stirring for 30min until the mixture is uniform and has no particles, then adding triethanolamine and stirring uniformly to obtain gel B, and naturally cooling to room temperature;
3) Mixing papain, sodium hyaluronate, mussel mucin, collagen and the rest water in the formula amount at 60rmp speed for 30min, adding into B gel, stirring at 60rmp speed for 40min, and stirring.
Example 2
The skin cream containing the papaya extract in the embodiment contains the following components in percentage by mass: 3% of papain, 1.6% of shea butter, 0.8% of tocopherol acetate, 0.4% of carbomer, 0.16% of triethanolamine, 0.04% of EDTA-disodium, 0.25% of sodium hyaluronate, 1.5% of mussel mucin, 2.0% of collagen, 3.0% of glycerol and the balance of purified water.
The preparation method of the skin cream containing the papaya extract comprises the following steps:
1) Mixing carbomer in a formula amount with 60% of water in the formula amount, stirring at 65 ℃ and 70rmp speed to form a uniform state, adding glycerol and EDTA-disodium in the formula amount, and stirring uniformly to obtain gel A;
2) Heating, stirring and dissolving shea butter and tocopherol acetate according to the formula amount at 62 ℃ and 60rmp rotating speed, then adding the mixture into the gel A at 62 ℃ and 60rmp stirring for 40min until the mixture is uniform and has no particles, then adding triethanolamine and stirring uniformly to obtain gel B, and naturally cooling to room temperature;
3) Mixing papain, sodium hyaluronate, mussel mucin, collagen and the rest water in the formula amount at the rotating speed of 60rmp for 30 minutes, adding the mixture into B gel, and stirring the mixture for 40 minutes at the rotating speed of 60 rmp.
Example 3
The skin cream containing the papaya extract in the embodiment contains the following components in percentage by mass: papain 4%, shea butter 2%, tocopherol acetate 1%, carbomer 0.3%, triethanolamine 0.12%, EDTA-disodium 0.05%, 1, 2-pentanediol 0.3%, mussel mucin 1.2%, collagen 2.0%, glycerol 2.0%, and the balance purified water.
The preparation method of the skin cream containing the papaya extract comprises the following steps:
1) Mixing carbomer in a formula amount with 60% of water in the formula amount, stirring at 63 ℃ and 70rmp speed to form a uniform state, adding glycerol and EDTA-disodium in the formula amount, and stirring uniformly to obtain gel A;
2) Heating, stirring and dissolving shea butter and tocopherol acetate according to the formula amount at 63 ℃ and 60rmp rotating speed, then adding the mixture into the gel A at 60 ℃, stirring at 70rmp for 30min until the mixture is uniform and has no particles, then adding triethanolamine and stirring uniformly to obtain gel B, and naturally cooling to room temperature;
3) Mixing papain, 1, 2-pentanediol, mussel mucin, collagen and the rest water in a formula ratio for 40min at a rotating speed of 60rmp, adding the mixture into the gel B, and stirring the mixture for 30min at a rotating speed of 70 rmp.
Example 4
The skin cream containing the papaya extract in the embodiment contains the following components in percentage by mass: 3% of papain, 1% of shea butter, 0.8% of tocopheryl acetate, 0.2% of hydroxyethyl cellulose, 0.1% of triethanolamine, 0.03% of EDTA-disodium, 0.3% of 1, 2-pentanediol, 1.8% of mussel mucin, 1.9% of collagen, 3.0% of glycerol and the balance of purified water.
The preparation method of the skin cream containing the papaya extract comprises the following steps:
1) Mixing hydroxyethyl cellulose with the amount of 50% of the amount of water according to the formula, stirring at 62 ℃ and 60rmp speed to form a uniform state, adding glycerol and EDTA-disodium according to the formula, and stirring uniformly to obtain gel A;
2) Heating, stirring and dissolving shea butter and tocopherol acetate according to the formula amount at 60 ℃ and 70rmp rotating speed, then adding the mixture into the gel A at 65 ℃, stirring at 60rmp for 40min until the mixture is uniform and granular, then adding triethanolamine and stirring uniformly to obtain gel B, and naturally cooling to room temperature;
3) Mixing papain, 1, 2-pentanediol, mussel mucin, collagen and the rest water in the formula ratio for 30min at the rotating speed of 60rmp, stirring uniformly, adding the mixture to B gel, stirring for 40min at the rotating speed of 60rmp, and stirring uniformly to obtain the gel B.
Example 5
The skin cream containing the papaya extract in the embodiment contains the following components in percentage by mass: 3% of papain, 1.4% of shea butter, 1% of tocopherol acetate, 0.2% of hydroxyethyl cellulose, 0.1% of triethanolamine, 0.04% of EDTA-disodium, 0.2% of 1, 2-hexanediol, 1.5% of mussel mucin, 2.0% of collagen, 3.0% of glycerol and the balance of purified water.
The preparation method of the skin cream containing the papaya extract comprises the following steps:
1) Mixing hydroxyethyl cellulose with the amount of 50% of the formula water, stirring at 61 deg.C and 60rmp speed to form a uniform state, adding glycerol and EDTA-disodium, and stirring to obtain gel A;
2) Heating, stirring and dissolving shea butter and tocopherol acetate according to the formula ratio at 65 ℃ and 70rmp rotating speed, then adding the mixture into the gel A at 65 ℃, stirring at 70rmp for 30min until the mixture is uniform and has no particles, then adding triethanolamine, stirring uniformly to obtain gel B, and naturally cooling to room temperature;
3) Mixing papain, 1, 2-hexanediol, mussel mucin, collagen and the rest water in the formula ratio at the rotating speed of 60rmp for 30min, stirring uniformly, adding the mixture to B gel, and stirring uniformly at the rotating speed of 60rmp for 30min to obtain the gel B.

Claims (8)

1. The skin cream containing the papaya extract is characterized by comprising the following components in percentage by mass: 2 to 4 percent of papain, 1 to 2 percent of emulsifier, 0.6 to 1 percent of tocopherol acetate, 0.2 to 0.5 percent of thickening agent, 0.1 to 0.2 percent of triethanolamine, 0.03 to 0.05 percent of EDTA-disodium, 0.2 to 0.3 percent of humectant, 1.2 to 1.8 percent of mussel mucin, 1.8 to 2.4 percent of collagen, 2 to 3 percent of glycerol and the balance of water.
2. The papaya extract-containing skin cream according to claim 1, wherein the thickener is carbomer or hydroxyethyl cellulose.
3. The papaya extract-containing skin cream as claimed in claim 1, wherein the moisturizer is one or more selected from the group consisting of sodium hyaluronate, 1, 2-pentanediol, and 1, 2-hexanediol.
4. The papaya extract-containing skin cream according to claim 1, wherein the emulsifier is shea butter.
5. The method for preparing the papaya extract-containing skin cream as set forth in claim 1, comprising the steps of:
1) Mixing the thickener with the amount of 50-60% of the water in the formula, uniformly stirring, adding the glycerin and the EDTA-disodium in the formula, and uniformly stirring to obtain gel A;
2) Heating, stirring and dissolving the emulsifier and the tocopherol acetate according to the formula amount, then adding the mixture into the gel A, heating and stirring the mixture until the mixture is uniform and has no particles, and then adding triethanolamine and stirring the mixture uniformly to obtain gel B;
3) Mixing papain, humectant, mussel mucin, collagen and residual water, adding into B gel, and stirring.
6. The method as claimed in claim 5, wherein the step 1) of mixing the thickener in a formula amount with water and stirring is carried out at a temperature of 60 to 65 ℃ and a rotation speed of 60 to 70 rmp; after the glycerol and the EDTA-disodium with the formula amount are added, the mixture is stirred at the temperature of 60-65 ℃ and the rotating speed of 60-70 rmp.
7. The method as claimed in claim 5, wherein the heating, stirring and dissolving of the emulsifier and the tocopherol acetate in the formula amount in the step 2) is carried out at a temperature of 60-65 ℃ and a rotation speed of 60-70 rmp; adding the mixture into the A gel, heating and stirring the mixture at the temperature of between 60 and 65 ℃, and stirring the mixture for 30 to 40min at the rotating speed of between 60 and 70 rmp.
8. The method as claimed in claim 5, wherein the mixing of the papain, the humectant, the mussel mucin, the collagen and the rest of the water in the formula amounts in step 3) is performed at 60 rmp-70 rmp for 30-40 min, and the adding to the B gel is performed at 60 rmp-70 rmp for 30-40 min.
CN202211681263.4A 2022-12-27 2022-12-27 Skin cream containing pawpaw extract and preparation method thereof Pending CN115737473A (en)

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Application Number Priority Date Filing Date Title
CN202211681263.4A CN115737473A (en) 2022-12-27 2022-12-27 Skin cream containing pawpaw extract and preparation method thereof

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Application Number Priority Date Filing Date Title
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Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070243155A1 (en) * 2006-04-18 2007-10-18 Pierre Bottiglieri Skin care method and products
CN103637928A (en) * 2013-12-13 2014-03-19 孙锐 Moisturizing and whitening gel and preparation method
CN110769800A (en) * 2017-03-30 2020-02-07 维生素C60生化学研究公司 Composition for cosmetic material containing fullerene

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070243155A1 (en) * 2006-04-18 2007-10-18 Pierre Bottiglieri Skin care method and products
CN103637928A (en) * 2013-12-13 2014-03-19 孙锐 Moisturizing and whitening gel and preparation method
CN110769800A (en) * 2017-03-30 2020-02-07 维生素C60生化学研究公司 Composition for cosmetic material containing fullerene

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