CN115736938A - Multi-mode physiological signal acquisition device - Google Patents
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Abstract
The invention provides a multi-mode physiological signal acquisition device, which comprises multi-mode acquisition of heart shock, heart sound and electrocardio signals. The heart beat and heart sound signals are collected using an array of 3 x 2 sensors. The heart and shock signal acquisition module comprises a heart and shock sensor array acquisition module and a signal simulation front end; the heart sound signal acquisition module comprises a heart sound sensor array acquisition module and a signal simulation front end; the electrocardiosignal acquisition module comprises an electrocardioelectrode and a signal simulation front end. And the multi-channel signals are synchronously managed by the FPGA to realize A/D sampling control, and the multi-channel signals are transmitted to the control module in real time. The MCU is responsible for system core control, signal processing, instruction sending to the sensor acquisition module and on-chip storage of the signals to obtain final multi-mode synchronous acquisition signals of the three signals of the heart, the sound and the electrocardio. The invention realizes the synchronous acquisition, storage and transmission of three physiological signals of the heart, the sound and the electrocardio.
Description
Technical Field
The invention relates to the technical field of signal detection and medical electronics, relates to technologies for collecting heart shocks, heart sounds and electrocardio, and particularly relates to a multi-mode physiological signal collecting device.
Background
Cardiovascular diseases are one of the important factors threatening the life and health of people worldwide at present, the early prevention and detection of cardiovascular diseases become great trend, and the direct medical cost of cardiovascular diseases can be effectively reduced. The above background greatly facilitates the research of early detection technology of cardiovascular diseases and out-of-hospital monitoring technology. Electrocardiographic examination is the most common clinical diagnostic tool for cardiovascular diseases. When an electrocardiogram is observed for heart diseases such as angina pectoris and myocardial infarction, the electrocardiogram is obviously changed. After years of research, the wearable electrocardiograph technology can effectively provide out-of-home monitoring and detection of heart diseases such as real-time, dynamic and continuous arrhythmia, atrial fibrillation and the like. Sometimes, however, for certain heart diseases, especially structural heart diseases, the electrocardiogram often does not change significantly, and heart sounds and shocks have been shown to provide the hemodynamic status of the heart. Therefore, the multi-modal physiological signals of the cardiac function, which are formed by combining the heart shock, the heart sound and the electrocardio, can reflect the health condition of the heart by integrating various technical means, make up for the deficiencies of the heart and provide information from different angles. And analysis and evaluation are carried out by combining a plurality of signals, and more aspects of multi-level and multi-angle information are fused compared with the single-mode signal.
Traditionally, identification of cardiac murmurs by artificial heart sound auscultation is a major means for cardiac function assessment screening. However, the analysis of heart sounds auscultated by a stethoscope is highly dependent on the experience and technique of experts. In recent years, with the development of artificial intelligence and big data technology, digital heart sounds have made progress and breakthrough in intelligent analysis for cardiovascular diseases. While the conventional technology is developed, the technology of acquiring the seismogram of the body surface at low frequency by a Micro Electro Mechanical System (MEMS) inertial sensor has attracted keen attention in recent years. It has been found that there are signal components in the sub-audible seismic signal that can be used to identify aortic valve stenosis, however the underlying mechanisms by which it functions remain to be further explored and studied. The heart beat is also verified to be capable of obtaining some effective hemodynamic parameters such as the left ventricular ejection time, the heart pre-ejection period and the like with the assistance of the electrocardiosignal. These parameters can also be used to assess changes in cardiac function due to structural heart disease. Therefore, the method combines the traditional heart sound and the emerging heart shock technology, is assisted by the electrocardio technology, is beneficial to forming a new wearable extrahospital heart function state evaluation means, enhances the development prediction capability and risk evaluation level of cardiovascular diseases, assists in deciding treatment time and means, and improves the treatment effect and the life quality of patients. Therefore, the invention provides a multi-modal physiological signal acquisition device which acquires three signals of heart shock, heart sound and electrocardio, provides a mode for comprehensively understanding various cardiac function conditions such as the hemodynamic condition of the heart and the like, especially provides possibility for early discovery and timely treatment of abnormality of structural heart diseases, and helps to avoid increase of medical cost and waste of medical resources.
Disclosure of Invention
In order to solve the problems, the invention provides a multi-modal physiological signal acquisition device, which realizes synchronous acquisition, storage and transmission of three physiological signals of heart shock, heart sound and electrocardio and reflects the health condition of the heart from the angle of the multi-modal physiological signals.
In order to achieve the purpose, the invention provides the following technical scheme:
a multi-modal physiological signal synchronous acquisition device, comprising: the system comprises a module for acquiring the heart shock, heart sound and electrocardio signals, a signal processing and control module and a communication module;
the three physiological signals are synchronously collected, and the heart shock and heart sound signals are collected by adopting 3 x 2 sensor arrays and are used for collecting multi-channel array signals of heart shock (heart sound) to obtain the shock and sound signals of the heart at different positions;
the heart and shock signal acquisition module comprises a heart and shock sensor array acquisition module and a signal simulation front end;
the heart sound signal acquisition module comprises a heart sound sensor array acquisition module and a signal simulation front end;
the electrocardiosignal acquisition module comprises an electrocardioelectrode and a signal simulation front end;
the signal processing and control module adopts the heterogeneity of FPGA and MCU;
the FPGA carries out synchronous management of acquisition clocks on the multi-channel signals of the heart shock, the heart sound and the electrocardio, realizes A/D sampling control and transmits the multi-channel signals to the control module in real time;
the MCU is responsible for system core control, is responsible for signal processing of the system, sends an instruction to the sensor acquisition module, and stores the signal on a chip to obtain a final multi-mode synchronous acquisition signal of the three signals of the heart, the sound and the electrocardio;
the communication module is responsible for data transmission, and outwards transmits the multi-mode signals of the heart shock, the heart sound and the electrocardio to realize the transmission function of the device.
Furthermore, the multi-mode signal synchronous acquisition device acquires an acquisition module for acquiring three physiological signals including a heart shock, a heart sound and an electrocardio, and acquires three physiological signals including the heart shock, the heart sound and the electrocardio.
Furthermore, the multi-modal signal synchronous acquisition device synchronously acquires three signals to be acquired, and the three acquired physiological signals are synchronous signals.
Furthermore, the acquisition modules of the heart shock and heart sound signals adopt sensor arrays. By forming a 3 x 2 sensor array by a plurality of sensors, the plurality of sensors can directionally enhance the cardiac shock (heart sound) signals by fusion arrangement, and the interference of the environment is reduced. The directivity and the spatial resolution of the sensor array are utilized to improve the quality of original signals and improve the capability of distinguishing the components of the heart-beat (heart sound) signals.
Furthermore, the heart-shake signal acquisition module comprises a heart-shake sensor array acquisition module and a signal simulation front end. The sensor array acquisition module is used for acquiring a plurality of paths of heart-shocking array signals at an acquisition part; the analog front end comprises an operational amplification module and a hardware filtering module, and is used for amplifying and filtering the seismic signals; the signal amplification module amplifies the heart-shaking signals; the hardware filtering module performs low-pass filtering, high-pass filtering and notch filtering on the heart-shaking signals, and filters out signal components outside the heart-shaking frequency band and power frequency interference of specific frequency components.
Furthermore, the heart sound signal acquisition module comprises a heart sound sensor array acquisition module and a signal simulation front end. The sensor array acquisition module is used for acquiring a plurality of paths of heart sound array signals at an acquisition part; the signal analog front end comprises an operational amplification module and a filtering module; the operational amplification module amplifies the heart sound signals, and the hardware filtering module performs low-pass filtering, high-pass filtering and notch filtering on the heart sound signals to filter out signal components outside a heart sound frequency band and power frequency interference of specific frequency.
Furthermore, the electrocardiosignal acquisition module comprises an acquisition electrode and a signal simulation front end. The collecting electrode is used for collecting electrocardiosignals; the analog front end comprises a signal amplification module and a filtering module; the signal amplification module amplifies the electrocardiosignals; the hardware filtering module performs low-pass filtering, high-pass filtering and notch filtering on the digital signal, and filters out signal components outside the electrocardio frequency band and power frequency interference of specific frequency.
Furthermore, the device adopts a heterogeneous mode of an FPGA and an MCU in a signal processing and control part. The FPGA carries out synchronous management of acquisition clocks on the multi-channel signals of the heart shock, the heart sound and the electrocardio, realizes A/D sampling control and transmits the multi-channel signals to the control module in real time; the MCU is responsible for system core control, signal processing of the system, instruction sending to the sensor acquisition module and on-chip storage of the signals to obtain final multi-mode synchronous acquisition signals of the three signals of the heart, the sound and the electrocardio.
Furthermore, the communication module can transmit the multi-mode signals outwards, and the data transmission function of the device is achieved.
Compared with the prior art, the invention has the following advantages and beneficial effects:
(1) The invention provides a multi-modal physiological signal synchronous acquisition device, which is used for synchronously acquiring signals of various sensors, synchronously acquiring three physiological signals of heart shock, heart sound and electrocardio and acquiring the health state information of the heart at different angles. And the synchronization among the three acquired physiological signals provides reliable guarantee for the analysis of subsequent multi-modal signals, such as the calculation of the characteristics of time difference, amplitude proportion and the like of characteristic points among different signals.
(2) The method is characterized in that the acquisition of the heart shake and heart sound signals is carried out in a multi-sensor array mode, a plurality of sensors form a 3-to-2 sensor array, the sensors are arranged in a fusion mode, the heart shake (heart sound) signals can be directionally enhanced, the environmental noise can be inhibited, and the signal to noise ratio is improved. Compared with a single sensor, the directivity and the spatial resolution among the sensor array signals are improved, the quality of original signals is improved, and the capacity of distinguishing the components of the heart shock signals and the heart sound signals is also improved.
(3) The multi-modal physiological signal acquisition integrates the traditional heart sound and the emerging heart-shaking technology, is assisted by the electrocardio signal, is the basis of the subsequent multi-modal signal joint analysis and detection of the heart health state, is favorable for forming a new-form heart health state evaluation and detection means, and provides possibility for early discovery and prevention of structural heart diseases.
Drawings
Fig. 1 is a schematic design diagram of the acquisition device system provided by the invention.
Fig. 2 is a schematic view of a sensor array of the present invention.
FIG. 3 is a schematic diagram of the collection and use of the device of the present invention.
Detailed Description
The technical solutions provided by the present invention will be described in detail below with reference to specific examples, and it should be understood that the following specific embodiments are only illustrative of the present invention and are not intended to limit the scope of the present invention.
The invention provides a multi-modal physiological signal synchronous acquisition device, which comprises an acquisition module of heart shock, heart sound and electrocardio signals, a signal processing and control module and a communication module, and is shown in figure 1. The method comprises the steps of synchronously acquiring three physiological signals, acquiring heart shock and heart sound signals by adopting 3X 2 sensor arrays, and acquiring multi-channel array signals of the heart shock (heart sound) to obtain the shock and sound signals of the heart at different positions. The heart and shock signal acquisition module comprises a heart and shock sensor array acquisition module and a signal simulation front end; the heart sound signal acquisition module comprises a heart sound sensor array acquisition module and a signal simulation front end; the electrocardiosignal acquisition module comprises an electrocardioelectrode and a signal simulation front end. The signal processing and control module adopts a heterogeneous mode of an FPGA and an MCU, the FPGA carries out synchronous management of acquisition clocks on the multi-channel signals of the heart shock, the heart sound and the electrocardio, the A/D sampling control is realized, and the multi-channel signals are transmitted to the control module in real time; the MCU is responsible for system core control, signal processing of the system, instruction sending to the sensor acquisition module and on-chip storage of the signals to obtain final multi-mode synchronous acquisition signals of the three signals of the heart, the sound and the electrocardio. The communication module can outwards transmit the multi-mode signals, and the data transmission function of the device is achieved. The specific implementation of each module is described in detail below.
The heart shake and heart sound signal acquisition module adopts a sensor array, the sensor array of 3 x 2 is formed by a plurality of sensors for acquisition, and the array arrangement condition is shown in figure 2. The 6 heart vibration (heart sound) sensors form a sensor array, and the sensor array is formed in a non-traditional auscultation area to collect signals. The array formed by a plurality of sensors is arranged in a fusion manner, so that the interference of environmental noise is reduced or inhibited, certain components of the cardiac shock (heart sound) signals can be directionally enhanced, the states of heart valves at different positions of the heart can be extracted or analyzed from the array signals, the directivity and the spatial resolution of the signals are increased by using the sensor array, the quality of original signals is improved, and different components in the cardiac shock (heart sound) signals are further distinguished.
In the specific application, the heart-shake signal acquisition module comprises a heart-shake signal acquisition module comprising a heart-shake sensor array acquisition module and a signal simulation front end. The cardiac signal employs a MEMS Inertial Measurement Unit (IMU) on the chest surface. Among them, the signals measured by the accelerometers in the IMU are generally called sesimocardio graphics (SCG), and the signals measured by the gyroscopes are Generally Called Gyrocardiographics (GCG). The cardiac signals can be resolved on the three axes of the coordinate system established on the body surface, i.e., the back-chest direction (z-axis), the left-right shoulder direction (x-axis), and the head-foot direction (y-axis). The acquisition of the multi-axial seismic signals can acquire multi-dimensional seismic signals from which the physiological condition of the heart is evaluated. The sensors were placed in a 3 x 2 array according to figure 2 and acquired multiple cardiac array signals. The analog front end comprises an operational amplification module and a hardware filtering module, and is used for amplifying and filtering the earthquake signals; the signal amplification module amplifies the heart-shaking signals; the hardware filtering module performs low-pass filtering, high-pass filtering and notch filtering on the heart-shaking signals, and filters out signal components outside the heart-shaking frequency band and power frequency interference of specific frequency.
The heart sound signal acquisition module comprises a heart sound sensor array acquisition module and a signal simulation front end. The heart sound sensor may employ a piezoelectric-based sensor, a microphone sensor, or a bone-conduction-based vibration sensor. The heart sound sensors are arranged according to the positions of fig. 2 to form a sensor array, and multi-channel heart sound array signal acquisition is carried out at the acquisition part. The signal analog front end comprises an operational amplification module and a filtering module. The operational amplification module amplifies the heart sound signals, and the hardware filtering module performs low-pass filtering, high-pass filtering and notch filtering on the heart sound signals to filter out signal components outside a heart sound frequency band and power frequency interference of specific frequency.
The electrocardiosignal acquisition module comprises an acquisition electrode and a signal simulation front end. The collecting electrode is arranged at the collecting part shown in figure 3 to collect the electrocardiosignals. The collecting electrode is used for collecting electrocardiosignals; the analog front end comprises a signal amplification module and a filtering module, wherein the signal amplification module is used for amplifying the electrocardiosignals; the hardware filtering module performs low-pass filtering, high-pass filtering and notch filtering on the digital signal, and filters out signal components outside the electrocardio frequency band and power frequency interference of specific frequency.
The processing and control part of the signal adopts the heterogeneity of FPGA and MCU. The signal acquisition mode of the device is multi-mode signal acquisition, and is characterized in that the number of channels is large, and signals acquired by the channels need to be synchronously transmitted to a control system. The FPGA has high performance and can achieve the acquisition and real-time processing of multi-channel signals. The FPGA carries out synchronous management of acquisition clocks on the multi-channel signals of the heart shock, the heart sound and the electrocardio, realizes A/D sampling control and transmits the multi-channel signals to the control module in real time. The synchronization among the three acquired physiological signals provides reliable guarantee for further analysis of subsequent multi-modal signals, such as calculation of time difference, amplitude ratio and other characteristics of characteristic points among different signals. The MCU is responsible for system core control, performs system signal processing, sends instructions to the sensor acquisition module and controls signal transmission of the communication module. The MCU can also store the signals on a chip to obtain final multi-mode synchronous acquisition signals of the three signals of the heart, the sound and the electrocardio of the heart, the heart and the heart.
The communication module adopts the WiFi wireless transmission technology, and the multimode signal that will gather outwards transmits, realizes the data transmission function of device.
The collecting device adopts a flexible patch process, is placed at a collecting part for collecting, and the specific collecting position is shown in figure 3. And a flexible patch process is adopted, so that the collection part can be attached, and the quality of the collected signal is improved.
The technical means disclosed by the invention are not limited to the technical means disclosed by the above embodiments, but also comprise technical solutions formed by any combination of the above technical features. It should be noted that modifications and adaptations can be made by those skilled in the art without departing from the principles of the present invention and are intended to be within the scope of the present invention.
Claims (9)
1. A multi-modality physiological signal acquisition device, comprising: the system comprises an acquisition module for three signals of the heart shock, heart sound and electrocardio, a signal processing and control module and a communication module;
the three physiological signals are synchronously acquired, the heart shock and heart sound signals are acquired by adopting 3 x 2 sensor arrays, and the multi-path array signals of the heart shock and the heart sound are acquired to obtain the shock and sound signals of the heart at different positions;
the heart and shock signal acquisition module comprises a heart and shock sensor array acquisition module and a signal simulation front end;
the heart sound signal acquisition module comprises a heart sound sensor array acquisition module and a signal simulation front end;
the electrocardiosignal acquisition module comprises an electrocardioelectrode and a signal simulation front end;
the signal processing and control module adopts a heterogeneous mode of an FPGA and an MCU;
the FPGA synchronously manages the acquisition clocks of the multi-channel signals of the heart shock, the heart sound and the electrocardio, realizes A/D sampling control and transmits the multi-channel signals to the control module in real time;
the MCU is responsible for system core control, is responsible for signal processing of the system, sends an instruction to the sensor acquisition module, and stores the signal on a chip to obtain a final multi-mode synchronous acquisition signal of the three signals of the heart, the sound and the electrocardio;
the communication module can transmit the multi-mode signals outwards, and the transmission function of three physiological signals of the heart, the vibration, the heart, the sound and the electrocardio is realized.
2. The multi-modal physiological signal acquisition device of claim 1, wherein: the multi-mode signal acquisition device carries out multi-mode wearable acquisition on three physiological signals of the heart shock, the heart sound and the electrocardio to obtain multi-mode physiological signals including the heart shock, the heart sound and the electrocardio.
3. The multi-modality physiological signal acquisition device of claim 1, wherein: the multi-mode signal acquisition device synchronously acquires three signals to be acquired, and the acquired three physiological signals are synchronous signals.
4. The multi-modality physiological signal acquisition device of claim 1, wherein: the acquisition module of heart shake and heart sound signal all adopted sensor array, constitute 3 x 2's sensor array through a plurality of sensors, arrange a plurality of sensors through the fusion and can directionally enhance heart shake and heart sound signal to reduce the interference of environment, utilize sensor array's directive property and spatial resolution, improve the quality of original signal, improve the ability of distinguishing heart shake and heart sound signal composition.
5. The multi-modality physiological signal acquisition device of claim 1, wherein: the heart-shake signal acquisition module comprises a heart-shake sensor array acquisition module and a signal simulation front end; the sensor array acquisition module is used for acquiring a plurality of paths of heart-shake array signals at an acquisition part; the analog front end comprises an operational amplification module and a hardware filtering module, and is used for amplifying and filtering the seismic signals; the signal amplification module amplifies the heart-shaking signals; the hardware filtering module performs low-pass filtering, high-pass filtering and notch filtering on the heart-shaking signals, and filters out signal components outside the heart-shaking frequency band and power frequency interference of specific frequency.
6. The multi-modality physiological signal acquisition device of claim 1, wherein: the heart sound signal acquisition module comprises a heart sound sensor array acquisition module and a signal simulation front end; the sensor array acquisition module is used for acquiring a plurality of paths of heart sound array signals at an acquisition part; the signal simulation front end comprises an operational amplification module and a filtering module; the operational amplification module amplifies the heart sound signal; the hardware filtering module performs low-pass filtering, high-pass filtering and notch filtering on the heart sound signal, and filters out signal components outside a heart sound frequency band and power frequency interference of specific frequency.
7. The multi-modality physiological signal acquisition device of claim 1, wherein: the electrocardiosignal acquisition module comprises an acquisition electrode and a signal simulation front end; the collecting electrode is used for collecting electrocardiosignals; the analog front end comprises a signal amplification module and a filtering module; the signal amplification module amplifies the electrocardiosignals; the hardware filtering module performs low-pass filtering, high-pass filtering and notch filtering on the digital signal, and filters out signal components outside the electrocardio frequency band and power frequency interference of specific frequency.
8. The multi-modal physiological signal synchronous acquisition device of claim 1, wherein: the device adopts a heterogeneous mode of an FPGA and an MCU in a signal processing and control module; the FPGA carries out synchronous management of acquisition clocks on the multi-channel signals of the heart shock, the heart sound and the electrocardio, realizes A/D sampling control and transmits the multi-channel signals to the control module in real time; the MCU is responsible for system core control, signal processing of the system, instruction sending to the sensor acquisition module and on-chip storage of the signals to obtain final multi-mode synchronous acquisition signals of the three signals of the heart, the sound and the electrocardio.
9. The multi-modality physiological signal acquisition device of claim 1, wherein: the communication module can transmit the multi-mode signals outwards, and the transmission function of three physiological signals of the heart, the vibration, the sound and the electrocardio is realized.
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| CN115137324A (en) * | 2022-05-20 | 2022-10-04 | 西安交通大学 | Human heart health monitoring system based on cloud-edge-end architecture |
| CN115192005A (en) * | 2022-08-03 | 2022-10-18 | 西安交通大学 | Portable electrocardiogram and seismogram combined acquisition system and data processing method |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN116671928A (en) * | 2023-07-27 | 2023-09-01 | 中国科学技术大学 | Bimodal cardiac electromechanical physiological source imaging system |
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