CN115569081A - Cosmetic composition comprising p-anisic acid and hydroxyacetophenone and cosmetic method thereof - Google Patents
Cosmetic composition comprising p-anisic acid and hydroxyacetophenone and cosmetic method thereof Download PDFInfo
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- CN115569081A CN115569081A CN202211221418.6A CN202211221418A CN115569081A CN 115569081 A CN115569081 A CN 115569081A CN 202211221418 A CN202211221418 A CN 202211221418A CN 115569081 A CN115569081 A CN 115569081A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/35—Ketones, e.g. benzophenone
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/36—Carboxylic acids; Salts or anhydrides thereof
- A61K8/368—Carboxylic acids; Salts or anhydrides thereof with carboxyl groups directly bound to carbon atoms of aromatic rings
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
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Abstract
Cosmetic compositions are provided comprising at least one aqueous phase and a combination of p-anisic acid and hydroxyacetophenone, wherein the pH of the composition is less than or equal to 6. Also provided are uses and cosmetic methods thereof.
Description
The present application is a divisional application of an invention patent application entitled "cosmetic composition comprising p-anisic acid and hydroxyacetophenone, use thereof, and cosmetic method thereof", having application number 2014, 12, 26, 2014, and 201480084367.4.
Technical Field
The present invention relates to a combination of p-anisic acid and hydroxyacetophenone, its use in aqueous cosmetic compositions for skin care, in particular as a cosmetic film (mask), and a cosmetic method using said cosmetic compositions.
Background
Cosmetic compositions are susceptible to microbial contamination during manufacture or consumer use. Preservatives are therefore used in cosmetic compositions to kill microorganisms that come into contact with these compositions. The preservative protects the product from microbial contamination that may occur during manufacture (also known as primary contamination) and protects the user from contamination or infection during use of the cosmetic composition (also known as secondary contamination).
Many different types of conventional preservatives have been developed to provide adequate antimicrobial activity to cosmetic compositions. These preservatives allow a good protection of the cosmetic composition during primary and/or secondary contaminations.
In addition, consumers seek a comfortable skin feel after application of the cosmetic composition. "comfortable skin feel" is intended to mean a soft, moisturizing, non-irritating and/or non-itchy feel after application of the cosmetic composition. Thus, a balance between sufficient antimicrobial activity and comfortable skin feel after application of a cosmetic composition is often a goal to be achieved by formulators in the cosmetic field.
So far, combinations of phenoxyethanol, p-anisic acid and methylparaben, for example, have been used in conventional cosmetic compositions for protecting them against microbial contamination.
However, such a combination is not entirely satisfactory, since it may not have the desired antimicrobial activity when used in any type of cosmetic composition, in particular when used in a composition in the form of an aqueous solution, more particularly in the form of a skin mask in the form of an aqueous solution. Furthermore, consumers desire improved comfortable skin feel after application, such as soft, moisturized, non-irritating and/or non-itchy feel, especially when the cosmetic composition is to be applied to the skin for an extended period of time, such as for a skin covering film.
There is therefore a need for cosmetic compositions which exhibit effective and broad spectrum antimicrobial activity and improved skin feel (i.e. soft, moisturized, non-irritating and/or non-itchy feel) during and/or after application, particularly after prolonged periods of time (e.g. 10 minutes) on the skin. There is also a need for stable and comfortable cosmetic compositions for application to the skin.
Disclosure of Invention
It is an object of the present invention to provide compositions having a pleasant skin feel during and/or after application of said compositions.
It is an object of the present invention to provide compositions having good antimicrobial activity during primary and/or secondary contamination, i.e. during manufacture and/or consumer use.
It is an object of the present invention to provide stable cosmetic compositions comprising a combination of p-anisic acid and hydroxyacetophenone.
It is an object of the present invention to provide an aqueous composition comprising the above combination having a pH of less than or equal to 6.
It is an object of the present invention to provide a cosmetic composition comprising the above combination for use as a skin mask, preferably a face mask.
It is an object of the present invention to provide a cosmetic composition in the form of an aqueous solution.
It is an object of the present invention to provide a skin care composition, preferably having a moisturizing effect.
The present invention therefore relates to a cosmetic composition comprising at least one aqueous phase and a combination of p-anisic acid and hydroxyacetophenone, wherein the pH of the composition is less than or equal to 6.
The invention also relates to the use of a combination of p-anisic acid and hydroxyacetophenone for the preparation of a cosmetic composition.
The invention also relates to the use of a cosmetic composition as defined above as a skin coating.
The present invention further relates to a cosmetic care method comprising the step of applying the cosmetic composition according to the invention to at least one area of skin.
Detailed description of the preferred embodiments
The inventors of the present invention have found that when a cosmetic composition comprising a combination of p-anisic acid and hydroxyacetophenone is topically applied, the combination used in the cosmetic composition of the present invention results in improved and/or comfortable skin feel.
Therefore, the combination of p-anisic acid and hydroxyacetophenone in the cosmetic composition according to the present invention is effective in preventing the growth of microorganisms and in compatibility with the skin.
The term "preservative" may refer to an agent contained in a cosmetic composition for the purpose of inhibiting the growth of microorganisms therein.
"pleasant skin feel" may mean at least one sensation selected from the group consisting of soft, moisturized, non-irritating, and non-itchy sensations on the skin upon and/or after topical application of the cosmetic composition of the present invention.
Thus, the cosmetic composition of the present invention comprises a combination of p-anisic acid and hydroxyacetophenone. The invention also relates to a combination of p-anisic acid and hydroxyacetophenone.
P-anisic acid is used in the cosmetic composition of the present invention.
P-anisic acid, which has a CAS number of 100-09-4, is also known as 4-anisic acid, 4-methoxybenzoic acid, p-methoxybenzoic acid or anisic acid (deaconic acid). P-anisic acid has the following formula (I):
mention may be made, for example, of the product sold by the company Merck under the name 4-methoxybenzoic acid.
According to the invention, the cosmetic composition further comprises hydroxyacetophenone.
More particularly, the cosmetic composition of the present invention comprises hydroxyacetophenone or p-hydroxyacetophenone having CAS number 99-93-4 and also known as 1- (4-hydroxyphenyl) -ethanone.
Hydroxyacetophenone has the following formula (II):
mention may be made of the Symsave name by Symrise ® H products sold.
The cosmetic composition of the present invention has a pH of less than or equal to 6. Preferably, the pH of the cosmetic composition is between (is comprised between) 4 and 6, more preferably between 5 and 6.
The invention also relates to the use of a combination of p-anisic acid and hydroxyacetophenone for the preparation of a cosmetic composition.
In one embodiment, the cosmetic composition of the invention comprises from 0.01% to 1% by weight, preferably from 0.05% to 0.5% by weight, more preferably from 0.1% to 0.2% by weight, of p-anisic acid, relative to the total weight of the composition.
In one embodiment, the cosmetic composition of the invention comprises from 0.01% to 1% by weight, preferably from 0.1% to 0.6% by weight, even more preferably from 0.4% to 0.6% by weight of hydroxyacetophenone, relative to the total weight of the composition.
According to a particular embodiment, the cosmetic composition of the invention comprises, relative to the total weight of the composition, from 0.05% to 0.5% by weight of p-anisic acid and from 0.1% to 0.6% by weight of hydroxyacetophenone.
In a particular embodiment, the cosmetic composition of the invention comprises 0.1% by weight of p-anisic acid and 0.5% by weight of hydroxyacetophenone, relative to the total weight of the composition.
More particularly, the cosmetic composition of the invention comprises, relative to the total weight of the composition, at least one aqueous phase, and a combination of:
-0.1 to 0.5% by weight of p-anisic acid, and
-from 0.1 to 0.6% by weight of hydroxyacetophenone,
wherein the pH of the composition is between 4 and 6.
In a particular embodiment, the cosmetic composition further comprises at least one glycol such as propylene glycol, at least one hydrophilic gelling agent and at least one humectant.
Physiologically acceptable medium
The cosmetic composition according to the invention may comprise a physiologically acceptable medium.
The term "physiologically acceptable medium" is intended to mean a medium particularly suitable for applying the composition of the invention to the skin or the lips.
The physiologically acceptable medium is generally adapted to the nature of the support (support) to which the composition should be applied, and also to the manner in which the composition is to be packaged.
Aqueous phase
The cosmetic composition of the present invention comprises an aqueous phase.
In one embodiment, the aqueous phase of the composition according to the invention comprises water.
According to one embodiment, the aqueous phase of the composition according to the invention represents at least 50% by weight, preferably at least 70% by weight, more preferably at least 80% by weight, relative to the total weight of the composition.
According to one embodiment, the cosmetic composition of the present invention is an aqueous solution. By "aqueous solution" it is meant a composition comprising at least 50% of an aqueous phase, said composition being in liquid form at room temperature (between 20 ℃ and 25 ℃) and atmospheric pressure (about 1 013,25 hPa).
The aqueous phase may also comprise a water-miscible organic solvent (at ambient temperatures of 20 ℃ to 25 ℃), such as, for example, monohydric alcohols having 2 to 6 carbon atoms, such as ethanol, isopropanol; polyols, in particular having from 2 to 20 carbon atoms, preferably having from 2 to 10 carbon atoms, and preferably having from 2 to 6 carbon atoms, such as glycerol, propylene glycol, butylene glycol, pentylene glycol, hexylene glycol, octylene glycol, dipropylene glycol, diethylene glycol; glycol ethers (in particular having 3 to 16 carbon atoms), e.g. monopropylene glycol, dipropylene glycol or tripropylene glycol (C) 1 -C 4 ) Alkyl ethers, monoethylene glycol, diethylene glycol or triethylene glycol (C) 1 -C 4 ) Alkyl ethers and mixtures thereof.
The aqueous phase may also comprise any water-soluble or water-dispersible compound that is compatible with the aqueous phase, such as gelling agents, film-forming polymers, thickeners, surfactants, and mixtures thereof.
According to a preferred embodiment, the present invention is an aqueous cosmetic solution comprising a combination of p-anisic acid and hydroxyacetophenone, wherein the pH of said solution is less than or equal to 6.
Active agent (actives)
In one embodiment, the cosmetic composition further comprises at least one cosmetic active agent, preferably selected from moisturizers, healing agents (healing agents) and/or anti-aging agents, more particularly from moisturizers.
Thus, the composition according to the invention may comprise a single active agent or a mixture of several active agents.
In a preferred embodiment, the humectant is selected from sodium hyaluronate, propylene glycol, sorbitol and/or mixtures thereof.
In one embodiment, the composition of the invention comprises between 0.01% and 15% by weight, preferably between 1% and 10% by weight, more preferably between 1% and 5% by weight of active agent, relative to the total weight of the composition.
Moisture retention agent
According to one embodiment, the composition further comprises at least one humectant (also known as a humectant).
Mention may in particular be made, as wetting or moisturizing agents, of sorbitol, polyols, preferably C 2 -C 8 Alcohols, and even more preferably C 3 -C 6 Alcohols, such as preferably glycerol, propylene glycol, 1, 3-butanediol, dipropylene glycol, diglycerol and mixtures thereof, glycerol and derivatives thereof, urea and derivatives thereof, especially Hydrovance (2-hydroxyethyl urea) sold by National Starch, lactic acid, hyaluronic acid, sodium hyaluronate, AHA, BHA, sodium oxyprolinate, xylitol, serine, sodium lactate, ectoin and derivatives thereof, chitosan and derivatives thereof, collagen, plankton (plankton), imperata (Moist 24) sold by SedermaImperata cylindrica) Extracts, homopolymers of acrylic acid such as Lipidure-HM from NOF Corporation ® Beta-glucan and in particular sodium carboxymethyl beta-glucan from Mibelle-AG-Biochemistry; by Nestle under the name NutraLipids ® A mixture of passion flower, apricot, corn and rice bran sold; c-glycoside derivatives such as those described in application WO 02/051828 and in particular C-beta-D-xylopyranoside-2-hydroxypropane, in a quantity of 30% by weight% active substance in the form of a solution in a water/propylene glycol mixture (60/40% by weight), such as that sold under the trade name of Chimex 171 MEXORYL SBB ® A prepared product; rosehip oil sold by Nestle; by Vincience under the name Alguarane Zinc ® Zinc-enriched microalgal porphyridium (Porphyromonas sp. (II) (III))Porphyridium cruentum) Extracting to obtain extract; spheres of collagen and chondroitin sulphate of marine origin (Atelocollagen) sold by Engelhard Lyon under the name marine filing spheres; hyaluronic acid spheres such as those sold by Engelhard Lyon; and arginine.
Preferably, a humectant selected from the group consisting of: glycerol, urea and derivatives thereof, especially hydro-vance sold by National Starch ® Hyaluronic acid AHA, BHA, acrylic acid homopolymers such as Lipidure-HM from NOF Corporation ® Beta-glucan and in particular sodium carboxymethyl beta-glucan from Mibelle-AG-Biochemistry; by Nestle under the name NutraLipids ® A mixture of passion flower, apricot, corn oil and rice bran sold; c-glycoside derivatives such as those described in application WO 02/051828 and in particular C-beta-D-xylopyranoside-2-hydroxypropane, in the form of a solution of 30% by weight of active substance in a water/propylene glycol mixture (60/40% by weight), such as that sold under the trade name \171by CHIMEX, MEXORYL SBB ® A product prepared from a mobile; rosehip oil sold by Nestle; by Vincience under the name Alguarane Zinc ® A marketed zinc-rich microalgal porphyridium extract; spheres of collagen and chondroitin sulfate of marine origin (atelocollagen) sold by Engelhard Lyon under the name marine filing spheres; hyaluronic acid spheres, such as those sold by Engelhard Lyon; and arginine.
In one embodiment, the humectant is selected from the group consisting of Lubrajel oil (Lubrajel oil), sodium hyaluronate, propylene glycol, sorbitol, and mixtures thereof.
Hydrophilic gelling agent
In one embodiment, the cosmetic composition further comprises at least one hydrophilic gelling agent.
Hydrophilic gelling agents which may be particularly mentioned include water-soluble or water-dispersible thickening polymers. These polymers may be chosen in particular from:
modified or unmodified carboxyvinyl polymers, such as the products sold under the name Carbopol (CTFA name: carbomer) by the company Goodrich;
-a polyacrylate;
polymethacrylates such as the products sold under the name Lubrajel and Norgel by the company Guardian or the products sold under the name Hispagel by the company Hispano Chimica;
-a polyacrylamide;
polymers and copolymers of 2-acrylamido-2-methylpropanesulfonic acid optionally crosslinked and/or neutralized, for example under the name Hostacerin AMPS, obtained from the Clariant company ® Poly (2-acrylamido-2-methylpropanesulfonic acid) sold under the CTFA name ammonium polyacryloyldimethyltaurate;
-crosslinked anionic copolymers of acrylamide and 2-acrylamido-2-methylpropanesulfonic acid; in the form of W/O (water-in-oil) emulsions, such as are known under the name Sepigel 305 (CTFA name: polyacrylamide/C) by the company SEPPIC 13- C 14 Isoparaffin/laureth-7) and a solvent under the name Simulgel 600 (CTFA name: acrylamide/sodium acryloyldimethyl taurate copolymer/isohexadecane/polysorbate 80);
polysaccharides, such as xanthan gum, guar gum, carob gum, gum arabic, scleroglucan, chitin and chitosan derivatives, carrageenan, gellan (gellan), alginates, such as the xanthan gum sold under the name Keltrol CG-T by the company CP Kelco,
cellulose, such as microcrystalline cellulose, carboxymethyl cellulose, hydroxymethyl cellulose and hydroxypropyl cellulose; and mixtures thereof.
In general, the polysaccharide according to the invention may be selected from polysaccharides produced by microorganisms; polysaccharides isolated from algae and polysaccharides from upper plants (upper plants), such as homogeneous polysaccharides, in particular cellulose and its derivatives and fructans, heterogeneous polysaccharides such as gum arabic, galactomannans, glucomannans, pectins and their derivatives.
In particular, the polysaccharide may be selected from fructans, exopolysaccharides, glucans, amylose, amylopectin, glycogen, pullulan (pullulan), dextran (dextran), cellulose and its derivatives, in particular methylcellulose, hydroxyalkylcellulose, ethylhydroxyethylcellulose and carboxymethylcellulose, mannans, xylans, lignins, arabinans, galactans, polygalacturonic acids, alginate-based compounds, chitin, chitosan, glucuronoxylan, arabinoxylans, xyloglucans, glucomannans, pectic acids and pectins, arabinogalactans, carrageenans, agar, glycosaminoglycans, gum arabic, tragacanth gum, ghatti gum, karaya gum, carob gum, galactomannans, such as guar gum and non-ionic derivatives, in particular hydroxypropyl guar gum, and ionic derivatives thereof, biopolysaccharide gums of microbial origin, in particular scleroglucan or xanthan gum, mucopolysaccharides, and in particular chondroitin sulfate and mixtures thereof.
Advantageously, the composition according to the invention comprises, as hydrophilic gelling agent, at least one polysaccharide chosen from: carrageenans, in particular k-carrageenan, gellan gum, agar, xanthan gum, alginate-based compounds, in particular sodium alginate, scleroglucan gum, guar gum, inulin, pullulan and mixtures thereof.
These polysaccharides can be modified chemically, in particular by urea, urethane groups or by hydrolysis, oxidation, esterification, etherification, sulfation, phosphorylation, amination, amidation, alkylation reactions or by a plurality of these modifications.
The derivatives obtained may be anionic, cationic, amphoteric or non-ionic.
Advantageously, said polysaccharide may be chosen from carrageenans, in particular k-carrageenan, gellan, agar, xanthan, alginate-based compounds, in particular sodium alginate, scleroglucan gum, guar gum, inulin, pullulan and mixtures thereof.
In general, compounds of this type suitable for use in the present invention are selected from those described in "Encyclopedia of Chemical Technology, kirk-Othmer, third Edition, 1982, volume 3, pages 896-900 and volume 15, pages 439-458", in "Polymers in Nature, E.A. Mc GREGOR and C.T. GREENWOOD, john Wiley & Sons Edition, chapter 6, pages 240-328, 1980", in a publication entitled "Handbook of Water solutions and resins" (1980) published by the Mc Graw Hill Book Company and in a publication entitled "Industrial guidelines" Polysaccharides and Derivatives ", roy L.ISER Edition, edition, edition Inc.
According to a particular embodiment, the hydrophilic gelling agent is a polysaccharide selected from xanthan gum, alginate-based compounds, in particular sodium alginate, scleroglucan gum, guar gum and mixtures thereof.
According to a particularly preferred embodiment, the hydrophilic gelling agent is xanthan gum.
Xanthan gum has a molecular weight between 1,000,000 g/mol and 50,000,000 g/mol and a viscosity (measured at 25 ℃ using a Brookfield LVT viscometer at 60 rpm) between 0.6 and 1.65 pa.s for an aqueous composition comprising 1% xanthan gum.
Xanthan gum is produced, for example, by Rhodia CHIMIE under the name Rhodicare, by Cargill texturing Solutions under the name SATIAXANE (for use in the food, cosmetic and pharmaceutical industries), by ADM under the name NOVAXAN and by CP-Kelco under the name Kelzan ® And Keltrol ® A product representative of the sale.
In one embodiment, the hydrophilic gelling agent is between 0.01 and 10% by weight, preferably between 0.1 and 5% by weight, more preferably between 0.1 and 1% by weight, relative to the total weight of the composition.
Additive agent
The cosmetic composition of the present invention may further comprise at least one physiologically acceptable additive. The cosmetic composition according to the invention may therefore further comprise any additive commonly used in the field in question, for example selected from additional gums, resins, dispersants, additional polymers, additional antioxidants, essential oils, preservatives, fragrances, neutralizing agents, bactericides (anti-static agents), anti-UV protectants and mixtures thereof.
The person skilled in the art can adjust the type and amount of additives present in the compositions according to the invention by means of routine operations, so that the cosmetic properties and the stability properties sought for these compositions are not affected by the additives.
Applications of
In one embodiment, the cosmetic composition as defined above is intended for topical application. The composition according to the invention may be a cosmetic composition intended for skin care. Thus, these compositions may be intended to be applied to the skin.
The invention also relates to the use of a cosmetic composition as defined above as a skin coating. In a particular embodiment, the composition as defined above is used as a body cover or mask, preferably a mask and more particularly a moisturizing mask.
By "for use as a skin overlay" is understood the application of a composition as defined above to at least one area of skin. The composition may or may not require rinsing with water.
By "rinse-off" can be meant that the composition (after being applied to the skin for an application time as defined below) is removed from the skin by a rinsing ingredient, such as water.
By "application time" is understood a sufficient time for the cosmetic composition to have an effect on the skin, such as a softening and/or moisturizing effect, and optionally not to cause skin irritation or discomfort. In one embodiment, the application time is between 5 and 15 minutes, preferably 10 minutes.
In one embodiment, the composition according to the invention is in the form of an aqueous solution, cream, emulsion or gel, preferably in the form of an aqueous solution.
In one embodiment, the cosmetic composition of the present invention is a film for application to the skin.
These compositions are used in the usual manner of using products of this type.
In one embodiment, the cosmetic composition according to the invention is in unit dose (single dose) form.
In this regard, the composition according to the invention has sufficient antimicrobial activity (especially during manufacture) to protect the composition from primary contamination.
Optionally, the compositions of the present invention are used with a substrate suitable for topical application to the skin, particularly the face.
In this regard, the substrate containing the composition according to the invention is then removed from the skin.
In particular, the substrate may be a coated paper (mask tissue) or a coated sheet (mask sheet), which is generally available on the market.
The present invention also relates to a cosmetic care process comprising the step of applying a cosmetic composition as defined above on at least one area of skin.
In one embodiment, the cosmetic process comprises a step of applying a cosmetic composition as defined above on at least one area of skin during an application time as defined above.
Throughout this application, the terms "comprise" or "include" mean "including at least one" or "including at least one," unless expressly specified otherwise.
Throughout the above specification, unless explicitly stated otherwise, the term "between x and y" is intended to mean an inclusive range, i.e. the values x and y are included in the range.
The invention will now be illustrated in the following non-limiting examples. Unless explicitly stated otherwise,% are expressed as weight relative to the total weight of the composition.
The compositions are prepared using conventional cosmetic composition formulation methods.
Examples
Example 1: cosmetic composition according to the invention
1. Composition tested:
composition a according to the invention was prepared as follows:
composition a was formulated according to methods known in the cosmetic art.
Composition a is a facial mask. It may or may not be used with a substrate. It can be washed off with or without water.
Composition a has a pH between 5.5 and 6.
Composition a is formulated according to techniques well known to those skilled in the art.
the antimicrobial activity of composition a according to the invention was tested.
Various types of microorganisms were introduced into the composition, and changes in the number of these microorganisms were observed using a spiral inoculator (spiral inoculator) named Eddy Jet 2 and an image analyzer named Flash & Go, manufactured by IUL corporation.
The table below shows the change in the total number of microorganisms after a certain period of contact with composition a according to the invention.
Antimicrobial activity was considered sufficient when a reduction in the total number of microorganisms was observed.
7. Results of antimicrobial testing after day:
results of antimicrobial testing after 1 month:
the results show that composition a according to the invention has a very broad (range) and effective antimicrobial activity.
the comfort test of the skin feel was carried out after application of the composition a according to the invention.
The composition a was combined with a base fabric produced by Nbond to obtain a sheet-like coating film according to the present invention.
The above sheet-like cover was applied 2 times for 10 minutes by 62 female panelists over a 5 day period, and then their faces were washed with water.
Panelists were asked to vote on the skin feel of the film, which was measured by a soft feel, moisturization, no irritation, and no itch feel.
As a result, 100% of panelists voted for "very good skin feel, no irritation and no itch during and after application" for the sheet-like cover film according to the present invention.
Thus, composition a was observed to have an effective and broad spectrum antimicrobial activity as well as an improved and pleasant skin feel after application.
Thus, the composition a according to the invention leads to a pleasant skin sensation after application, in particular to a sensation of absence of irritation and/or itching.
Furthermore, after leaving the composition of the invention at 4 ℃, room temperature (25 ℃), 40 ℃ and 45 ℃, the composition was stable over a 2 month period.
Claims (14)
1. A cosmetic composition comprising at least one aqueous phase and a combination of:
0.1 to 0.5% by weight of p-anisic acid, and
0.1 to 0.6% by weight of hydroxyacetophenone,
relative to the total weight of the composition, and
wherein the pH of the composition is between 5.5 and 6.
2. The cosmetic composition of claim 1, which is an aqueous solution.
3. Cosmetic composition according to claim 1 or 2, comprising from 0.1% to 0.2% by weight of p-anisic acid, relative to the total weight of the composition.
4. The cosmetic composition of claim 1 or 2, further comprising at least one cosmetic active.
5. The cosmetic composition of claim 4, wherein the at least one cosmetic active agent is a humectant.
6. The cosmetic composition according to claim 1 or 2, further comprising at least one hydrophilic gelling agent.
7. The cosmetic composition according to claim 6, wherein the at least one hydrophilic gelling agent is chosen from polysaccharides.
8. The cosmetic composition of claim 7, wherein the polysaccharide is xanthan gum.
9. Cosmetic composition according to claim 6, in which the hydrophilic gelling agent is between 0.01 and 10% by weight relative to the total weight of the composition.
10. Cosmetic composition according to claim 6, in which the hydrophilic gelling agent is between 0.1% and 5% by weight relative to the total weight of the composition.
11. Cosmetic composition according to claim 6, in which the hydrophilic gelling agent is between 0.1% and 1% by weight relative to the total weight of the composition.
12. Use of a cosmetic composition according to any one of claims 1 to 11 as a skin coating.
13. Use of the cosmetic composition according to claim 12 as a mask.
14. A cosmetic care method comprising the step of applying the cosmetic composition according to any one of claims 1 to 11 to at least one area of skin.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202211221418.6A CN115569081A (en) | 2014-12-26 | 2014-12-26 | Cosmetic composition comprising p-anisic acid and hydroxyacetophenone and cosmetic method thereof |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202211221418.6A CN115569081A (en) | 2014-12-26 | 2014-12-26 | Cosmetic composition comprising p-anisic acid and hydroxyacetophenone and cosmetic method thereof |
| PCT/CN2014/095138 WO2016101264A1 (en) | 2014-12-26 | 2014-12-26 | Cosmetic compositions comprising p-anisic acid and hydroxyacetophenone, their uses and cosmetic methods thereof |
| CN201480084367.4A CN107106434A (en) | 2014-12-26 | 2014-12-26 | Cosmetic composition comprising paraanisic acid and hydroxyacetophenone, its purposes and its cosmetic method |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201480084367.4A Division CN107106434A (en) | 2014-12-26 | 2014-12-26 | Cosmetic composition comprising paraanisic acid and hydroxyacetophenone, its purposes and its cosmetic method |
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| Publication Number | Publication Date |
|---|---|
| CN115569081A true CN115569081A (en) | 2023-01-06 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202211221418.6A Pending CN115569081A (en) | 2014-12-26 | 2014-12-26 | Cosmetic composition comprising p-anisic acid and hydroxyacetophenone and cosmetic method thereof |
| CN201480084367.4A Pending CN107106434A (en) | 2014-12-26 | 2014-12-26 | Cosmetic composition comprising paraanisic acid and hydroxyacetophenone, its purposes and its cosmetic method |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201480084367.4A Pending CN107106434A (en) | 2014-12-26 | 2014-12-26 | Cosmetic composition comprising paraanisic acid and hydroxyacetophenone, its purposes and its cosmetic method |
Country Status (2)
| Country | Link |
|---|---|
| CN (2) | CN115569081A (en) |
| WO (1) | WO2016101264A1 (en) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106176480A (en) * | 2016-08-30 | 2016-12-07 | 广州品赫化妆品有限公司 | A kind of food grade compositions with antiseptic activity and the application in cosmetics thereof |
| FR3090272B1 (en) * | 2018-12-20 | 2022-03-18 | Oreal | Antimicrobial mixture containing 4-(3-ethoxy-4-hydroxyphenyl)butan-2-one and an alcohol compound, and composition containing same |
| US20220023173A1 (en) * | 2018-12-20 | 2022-01-27 | L'oreal | Antimicrobial mixture containing 4-(3-ethoxy-4-hydroxyphenyl)butan-2-one and an alcohol compound, and cosmetic composition containing same |
| CN113710331B (en) | 2019-03-12 | 2024-03-22 | 西姆莱斯股份公司 | Antimicrobial mixture |
| CN114222554B (en) * | 2019-06-28 | 2024-03-12 | 莱雅公司 | Cosmetic composition for making up and/or caring for keratin materials |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2834459B1 (en) * | 2002-01-07 | 2006-08-04 | Oreal | MICROBICIDE AGENT AND COSMETIC TREATMENT COMPOSITION CONTAINING THE SAME |
| CN104188874B (en) * | 2014-09-18 | 2017-03-29 | 湖南御家化妆品制造有限公司 | A kind of gentle moisturizing mask |
-
2014
- 2014-12-26 CN CN202211221418.6A patent/CN115569081A/en active Pending
- 2014-12-26 CN CN201480084367.4A patent/CN107106434A/en active Pending
- 2014-12-26 WO PCT/CN2014/095138 patent/WO2016101264A1/en active Application Filing
Also Published As
| Publication number | Publication date |
|---|---|
| CN107106434A (en) | 2017-08-29 |
| WO2016101264A1 (en) | 2016-06-30 |
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