CN114965995B - Immunochromatography analysis detection system and method - Google Patents
Immunochromatography analysis detection system and method Download PDFInfo
- Publication number
- CN114965995B CN114965995B CN202210560647.4A CN202210560647A CN114965995B CN 114965995 B CN114965995 B CN 114965995B CN 202210560647 A CN202210560647 A CN 202210560647A CN 114965995 B CN114965995 B CN 114965995B
- Authority
- CN
- China
- Prior art keywords
- detection
- module
- information
- test paper
- channel
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Images
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/558—Immunoassay; Biospecific binding assay; Materials therefor using diffusion or migration of antigen or antibody
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Abstract
The invention discloses an immunochromatography analysis detection system and method, which relate to the field of immunochromatography and comprise a box body, wherein a plurality of detection channels are arranged in the box body, a driving module is arranged on the upper side of the box body, a moving module and a separating module are arranged in each of the plurality of detection channels, and the separating module divides the corresponding detection channel into a channel I and a channel II; the driving module comprises a plurality of output ends extending to the interior of the corresponding detection channel, and the plurality of output ends are provided with detection position modules; the detection position modules are used for driving the detection test paper to contact with the sample and move along the corresponding detection channels. According to the invention, each detection channel can form different spaces in a single detection channel through the separation module during continuous detection, and the two groups of spaces have a disinfection function, so that the problem of detection errors caused by pollution can be avoided during continuous detection.
Description
Technical Field
The invention relates to the field of immunochromatography, in particular to an immunochromatography analysis detection system and method.
Background
Immunochromatography is a commonly used rapid diagnostic technique, and generally, one end of a test strip is dipped into a sample, after the end is dipped into the sample, the sample moves forwards along the membrane due to capillary action, when the test strip moves to a region where an antibody is fixed, a corresponding antigen in the sample is specifically combined with the antibody, and if immune colloidal gold is used, the region can show a certain color.
Through retrieval, the Chinese patent discloses a multichannel synchronous immunochromatographic detection system and a detection method (publication number: CN 109490535B), the patent comprises a box body and a test strip, the box body is provided with a first sample adding hole and a plurality of observation windows, and a second sample adding hole is arranged between the first sample adding hole and each observation window; a plurality of percolation channels are arranged on the test strip, and the percolation channels pass through the first sample adding hole, the observation window and the lower part of the second sample adding hole; the device also comprises a motion mechanism, a photoelectric detector and a control computer, wherein the motion mechanism is used for driving the box body to do linear motion; the photoelectric detector outputs the detection result to the control computer in the form of an electric signal; and the control computer receives the detection result transmitted by the photoelectric detector to obtain the detection result of each detected sample on the test strip.
In the prior art, when a plurality of groups of samples are detected, multiple channels are generally adopted to synchronously detect the samples, but when the plurality of groups of samples are continuously detected synchronously, the problem of pollution among the samples or the channels is easily caused, and the detection result is influenced.
Disclosure of Invention
In order to solve the above technical problems, the present invention provides an immunochromatographic assay detection system comprising:
the detection device comprises a box body, a detection module and a control module, wherein the box body is used for loading all components and modules in the system, a plurality of detection channels are arranged in the box body, and the upper side of the box body is provided with the drive module;
the detection device comprises detection channels, wherein a plurality of detection channels are internally provided with a moving module and a separating module, the moving module is used for driving the separating module to move at two sides of the corresponding detection channel, and when the separating module moves to two sides of the detection channel, the corresponding detection channel is divided into a channel I and a channel II;
the driving module is provided with a plurality of output ends, the output ends respectively extend into the detection channels, and each output end of the driving module is provided with a detection position module;
the detection position modules move synchronously and are used for driving the detection test paper to contact with the sample and driving the detection test paper to move along the corresponding detection channel;
the image detection module and the detection position module move synchronously, generate image information corresponding to the detection position module and the detection test paper in the detection position module, and transmit the image information to the processing module;
and the processing module is used for receiving and analyzing the image information to obtain detection data.
Preferably, the following components: the inside sample storage module that is provided with of box body, inside fixture and the first disinfection module of being provided with of sample storage module, fixture is used for fixing the sample, first disinfection module is used for when changing the sample, disinfects the inner space of sample storage module, avoids follow-up sample to be contaminated.
Preferably: the method comprises the steps that samples are classified according to any one group or combination of multiple groups of region information, occupation information, age information and gender information, a radio frequency module is installed in detection test paper and used for recording any one group or combination of multiple groups of region information, occupation information, age information and gender information, corresponding detection test paper is selected according to various items of information of the samples during detection, and the detection position module comprises a radio frequency identification unit and is used for identifying the information corresponding to the detection test paper to obtain detection personnel information, and the detection personnel information is matched with detection data and then is transmitted to a processing module;
the processing module classifies and stores the information of the detection personnel and is used for assisting the detection result and the detection personnel to carry out overall planning, so that whether the detection result is related to the relevant information of the detection personnel or not is conveniently identified.
Preferably: the separation module comprises a plurality of second disinfection units which are symmetrically arranged at two sides of the separation module and are respectively marked as an X1 part and an X2 part;
the inner walls of the two sides of the channel module are respectively marked as an A1 part and an A2 part, the two sides corresponding to the separation module are respectively marked as a B1 part and a B2 part, and the use method of the separation module comprises the following steps:
y1: the part B1 of the separation module is attached to the part A1 of the corresponding channel module, the space between the part B2 of the separation module and the part A2 of the corresponding channel module is a channel I, and the part X1 of the second disinfection unit is positioned between the part A1 and the part B1 and disinfects the inner space of the second disinfection unit;
y2: the B2 position of the separation module is attached to the A2 position of the corresponding channel module, the space between the B1 position of the separation module and the A1 position of the corresponding channel module is a channel II, and the X2 part of the second disinfection unit is located between the A2 position and the B2 position and disinfects the inner space of the second disinfection unit.
Preferably: the detection bit module comprises:
the clamping unit is used for clamping the test paper, driving the test paper to move, and keeping the test paper in a stable state when the test paper moves, namely the clamping unit does not move relative to the test paper;
the rotation unit, the rotation unit is used for driving the centre gripping unit and rotates for carry out the rotation of first direction and second direction respectively with test paper, when test paper carries out the rotation of first direction, contact with the sample, and when test paper carries out the rotation of second direction, with the one end perk of test paper with the sample contact, avoid the sample to drip to the box body in, cause the pollution to it.
Preferably: the image detection module includes:
the image recognition unit is used for recognizing an antibody region of the detection test paper, generating image information I and image information II, transmitting the image information I to the processing module and transmitting the image information II to the gray level conversion unit;
the gray level conversion unit is used for receiving the image information II, then carrying out gray level processing on the image information to obtain gray level image information and transmitting the gray level image information to the processing module;
the processing module is provided with preset analysis data, and after receiving the image information I and the gray image information, the processing module compares the image information I and the gray image information with the preset analysis data to obtain detection data.
Preferably, the following components: the method for recognizing the antibody region by the image recognition unit comprises the following steps:
z1: the method comprises the steps of establishing a first coordinate system in advance, establishing edge simulation information of the detection test paper according to size information of the detection test paper, matching any end of the edge simulation information with a coordinate origin of the first coordinate system, generating position information by the rest end points of the edge simulation information around the coordinate origin of the first coordinate system, marking one end of the edge simulation information matched with the coordinate origin of the first coordinate system as H1, and marking an antibody area of the detection test paper in the first coordinate system as K1 according to the edge simulation information;
z2: after the detection test paper to be detected and the detection position module are assembled, the image recognition unit recognizes the edge information of the detection test paper to be detected and generates edge information I to be recognized, then the edge information I to be recognized is compared with edge simulation information to obtain end point information H2 matched with a first coordinate system, meanwhile, based on the end point information H2, the end point information H2 is overlapped with H1, the edge information I to be recognized is matched with the first coordinate system, after the matching, each coordinate point of the edge information I to be recognized on the first coordinate system is coincided with the coordinate point of the corresponding part in the edge simulation information, meanwhile, the edge information I to be recognized generates an antibody recognition area marked as K2 based on the K1 area,
z3: after the detection test paper to be detected is contacted with a sample, the color of the antibody area changes, the image recognition unit recognizes the corresponding image information I in the K2 area, and the image information I is copied to obtain image information II.
The invention also discloses an immunochromatographic assay detection method, which comprises the following steps:
the method comprises the following steps: installing a plurality of groups of samples into a box body, and installing the detection test paper into each detection position module based on the classification sequence of the plurality of groups of samples;
step two: the image detection module identifies the antibody region of each detection test paper, starts the moving module in each detection channel, and moves the separation module to form a corresponding channel I or channel II;
step three: the driving module and the detection position module drive the detection test paper to incline and then contact with the sample, the detection test paper is separated from the sample after the contact, the detection test paper is kept to incline at the same angle, the holding time is S, the value range of S is 0.5-3.5S, the value of S is based on the fluidity of the sample, the higher the fluidity of the sample is, the larger the value of S is, and then the detection position module drives the detection test paper to incline in the opposite direction;
step four: the image detection module and the detection test paper rotate at the same angle, and the identified image information is transmitted to the processing module;
step five: the processing module obtains detection data based on the image information.
The invention has the technical effects and advantages that:
the detection device is provided with a plurality of detection channels in the box body, can detect a plurality of samples at the same time, and can match detection results with corresponding information based on various information of the samples during detection, so that relevant relevance information can be obtained during detection;
in addition, each detection channel can form different spaces in a single detection channel through the separation module during continuous detection, and the two groups of spaces have the disinfection function, so that the problem of detection errors caused by pollution can be avoided during continuous detection;
on the other hand, the image detection module mainly identifies the antibody part region of the detection test paper when identifying the detection test paper, thereby avoiding the influence of other parts of the detection test paper on image identification, and also producing a gray image when carrying out image identification, thereby further improving the accuracy of the image identification.
Drawings
FIG. 1 is a system diagram of an immunochromatographic assay detection system of the present invention.
The invention is described in further detail below with reference to the drawings and the detailed description. The embodiments of the present invention have been presented for purposes of illustration and description, and are not intended to be exhaustive or limited to the invention in the form disclosed. Many modifications and variations will be apparent to those of ordinary skill in the art. The embodiment was chosen and described in order to best explain the principles of the invention and the practical application, and to enable others of ordinary skill in the art to understand the invention for various embodiments with various modifications as are suited to the particular use contemplated.
Detailed Description
The following examples are included:
example 1
Referring to fig. 1, an immunochromatographic assay detection system includes a cartridge, a detection channel, a driving module, a detection position module, an image detection module, and a processing module;
the box body is used for each component and the module in the loading system, the inside a plurality of detection channel that is provided with of box body, and the drive module is installed to the upside of box body, the inside of box body is provided with sample storage module, inside fixture and the first disinfection module of being provided with of sample storage module, fixture is used for fixing the sample, first disinfection module is used for when changing the sample, disinfects the inner space of sample storage module, avoids follow-up sample to be contaminated.
The mobile modules are used for driving the separation modules to move at two sides of the corresponding detection channels, and when the separation modules move to two sides of the detection channels, the interiors of the corresponding detection channels are respectively divided into a channel I and a channel II;
the driving module is provided with a plurality of output ends which respectively extend into each detection channel, and each output end of the driving module is provided with a detection position module;
the detection position modules move synchronously, and the detection position modules are used for driving the detection test paper to contact with the sample and driving the detection test paper to move along the corresponding detection channel;
the image detection module and the detection position module move synchronously, generate image information corresponding to the detection position module and the detection test paper in the detection position module, and transmit the image information to the processing module;
the processing module is used for receiving and analyzing the image information to obtain detection data.
The detection device comprises a detection position module, a processing module and a display module, wherein the sample is classified according to any one group or combination of multiple groups of region information, occupation information, age information and gender information, a radio frequency module is installed in the detection test paper and used for recording any one group or combination of multiple groups of region information, occupation information, age information and gender information, when in detection, the corresponding detection test paper is selected according to various information of the sample, and the detection position module comprises a radio frequency identification unit and is used for identifying the information of the corresponding detection test paper to obtain the information of detection personnel, and the information of the detection personnel is matched with the detection data and then is transmitted to the processing module;
the processing module classifies and stores the information of the detection personnel and is used for assisting the detection result and the detection personnel to carry out overall planning, so that whether the detection result is related to the relevant information of the detection personnel or not is conveniently identified.
The separation module comprises a plurality of second disinfection units which are symmetrically arranged on two sides of the separation module and are respectively marked as an X1 part and an X2 part.
The inner walls of the two sides of the channel module are respectively marked as an A1 part and an A2 part, the two sides of the corresponding separation module are respectively marked as a B1 part and a B2 part, and the using method of the separation module comprises the following steps:
y1: the part B1 of the separation module is attached to the part A1 of the corresponding channel module, the space between the part B2 of the separation module and the part A2 of the corresponding channel module is a channel I, and the part X1 of the second disinfection unit is positioned between the part A1 and the part B1 and disinfects the channel I;
y2: the B2 part of the separation module is attached to the A2 part of the corresponding channel module, the space between the B1 part of the separation module and the A1 part of the corresponding channel module is a channel II, and the X2 part of the second disinfection unit is positioned between the A2 part and the B2 part and disinfects the channel II.
The detection position module comprises:
the clamping unit is used for clamping the detection test paper, driving the detection test paper to move, and keeping the detection test paper in a stable state when the detection test paper moves, namely the clamping unit does not move relative to the detection test paper;
the rotation unit, the rotation unit is used for driving the centre gripping unit and rotates for carry out the rotation of first direction and second direction respectively with test paper, when test paper carries out the rotation of first direction, contact with the sample, and when test paper carries out the rotation of second direction, with the one end perk of test paper with the sample contact, avoid the sample to drip to the box body in, cause the pollution to it.
The image detection module includes:
the image recognition unit is used for recognizing an antibody region of the detection test paper, generating image information I and image information II, transmitting the image information I to the processing module and transmitting the image information II to the gray level conversion unit;
the gray level conversion unit is used for receiving the image information II, then carrying out gray level processing on the image information to obtain gray level image information and transmitting the gray level image information to the processing module;
the processing module is provided with preset analysis data, and after the processing module receives the image information I and the gray image information, the image information I and the gray image information are compared with the preset analysis data to obtain detection data.
A method for recognizing an antibody region by an image recognition unit, comprising the steps of:
z1: establishing a first coordinate system in advance, establishing edge simulation information of the detection test paper according to the size information of the detection test paper, matching any end of the edge simulation information with the origin of coordinates of the first coordinate system, generating position information in the first coordinate system, marking one end of the edge simulation information matched with the origin of the first coordinate system as H1, and marking an antibody area of the detection test paper in the first coordinate system as K1 according to the edge simulation information;
z2: after the detection test paper to be detected and the detection position module are assembled, the image recognition unit recognizes the edge information of the detection test paper to be detected and generates edge information I to be recognized, then the edge information I to be recognized is compared with edge simulation information to obtain end point information H2 matched with a first coordinate system, meanwhile, based on the end point information H2, the end point information H2 is overlapped with H1, the edge information I to be recognized is matched with the first coordinate system, after the matching, each coordinate point of the edge information I to be recognized on the first coordinate system is coincided with the coordinate point of the corresponding part in the edge simulation information, meanwhile, the edge information I to be recognized generates an antibody recognition area marked as K2 based on the K1 area,
z3: after the detection test paper to be detected contacts with the sample, the color of the antibody region changes, the image recognition unit recognizes the corresponding image information I in the K2 region, and copies the image information I to obtain image information II.
The working principle is as follows:
installing a plurality of groups of samples into a sample receiving module of a box body, sterilizing the sample receiving module and an installation area thereof through a first sterilizing module before installation to prevent the samples from being polluted, then installing detection test paper into each detection position module based on the classification sequence of the plurality of groups of samples, selecting edge simulation information corresponding to the detection test paper according to the neutralization size of the detection test paper, and combining the edge simulation information with a first coordinate system;
the image detection module identifies the antibody area of each detection test paper, the edge of the detection test paper to be detected is identified and is compared with edge simulation information in a first coordinate system to obtain a K2 area to be identified, then the moving module in each detection channel is started, the separation module is moved to form a corresponding channel I or channel II, after a channel for pairing is formed, the X1 part or the X2 part of the second disinfection module in the unused channel is started, and the side walls of the detection channel and the separation module and the space between the side walls are disinfected;
the driving module drives the detection position module and the detection test paper to move to the upper side of the corresponding sample, the rotating unit in the detection position module drives the detection test paper to incline towards the sample direction, the detection test paper is contacted with the sample, the detection test paper is separated from the sample after the contact, the detection test paper is kept to incline at the same angle, the keeping time is S, the S is preferably 3S, and then the detection position module drives the detection test paper to incline towards the opposite direction, so that the sample is prevented from dropping in the box body;
when the rotation unit drives the detection test paper to rotate, the image detection module and the detection test paper rotate at the same angle, the stability of image recognition is kept, recognized image information is transmitted to the processing module, a sample flows to an antibody area of the detection test paper based on capillary action, the color change occurs in the antibody area, meanwhile, the image detection module detects that the color change occurs in a K2 area, image information I is generated, the image information I is copied, image information II is obtained, meanwhile, based on the image information II, the gray level conversion unit converts the image information II into gray level image information, and then the image information I and the gray level image information are transmitted to the processing module;
and the processing module identifies the K2 area based on the image information I and the gray image information to obtain detection data.
The concrete case is as follows:
when the epidemic disease detection is carried out in a certain area, classifying patients by age and gender, wherein males aged 0-18 are C1, males aged 18-60 are C2, males aged over 60 are C3, females aged 0-18 are N1, females aged 18-60 are N2, and females aged over 60 are N3, and respectively obtaining six samples;
during detection, the six groups of samples are circularly arranged according to the sequence of C1, C2, C3, N1, N2 and N3, and the detection test paper provided with the corresponding radio frequency units is sequentially arranged in the corresponding detection position modules and used for corresponding the detection data with the age of the area;
during detection, a worker starts the moving module, moves the separation module, uses the channel after each detection channel is disinfected, then starts the detection system, and displays the image information I and the gray image information normally through observation;
after the detection data of each sample is obtained, it can be guessed that the prevalence rate of the epidemic disease is higher in the adult and the elderly population, and the male probability is higher than that of the female, as seen that the prevalence rate of C1 is 0.03%, the prevalence rate of C2 is 0.133%, the prevalence rate of C3 is 0.12%, the prevalence rate of N1 is 0.025%, the prevalence rate of N2 is 0.098%, and the prevalence rate of N3 is 0.105%.
It is to be understood that the described embodiments are merely a few embodiments of the invention, and not all embodiments. All other embodiments, which can be derived by one of ordinary skill in the art and related arts based on the embodiments of the present invention without any creative effort, shall fall within the protection scope of the present invention. Structures, devices, and methods of operation not specifically described or illustrated herein are generally practiced in the art without specific recitation or limitation.
Claims (7)
1. An immunochromatographic assay detection system, comprising:
the detection device comprises a box body, a detection module and a control module, wherein a plurality of detection channels are arranged in the box body, and the upper side of the box body is provided with the drive module;
the detection device comprises detection channels, wherein a plurality of detection channels are internally provided with a moving module and a separating module, and the moving module is used for driving the separating module to move at two sides of the corresponding detection channel, so that the corresponding detection channel is divided into a channel I and a channel II;
the separation module comprises a plurality of second disinfection units, the second disinfection units are symmetrically arranged on two sides of the separation module and are respectively marked as an X1 part and an X2 part, and the X1 part and the X2 part are used for disinfecting a corresponding channel I or a channel II;
the driving module comprises a plurality of output ends extending to the interior of the corresponding detection channel, and the plurality of output ends are provided with detection position modules;
the detection position modules are used for driving the detection test paper to be in contact with the sample and move along the corresponding detection channels;
the image detection module moves synchronously with the detection position module, generates image information corresponding to the detection test paper and transmits the image information to the processing module;
and the processing module is used for receiving and analyzing the image information to obtain detection data.
2. The immunochromatographic assay detection system of claim 1, wherein a radio frequency module is installed in the detection test paper, and the radio frequency module is used for recording any one or combination of multiple groups of regional information, occupational information, age information and sex information of the sample;
the detection position module comprises a radio frequency identification unit for identifying information corresponding to the detection test paper.
3. The immunochromatographic assay detection system of claim 1, wherein the detection site module comprises:
the clamping unit is used for clamping the test paper and driving the test paper to move;
and the rotating unit is used for driving the clamping unit to rotate and is used for contacting and separating the detection test paper with the sample.
4. The immunochromatographic assay detection system of claim 1, wherein the image detection module comprises:
the image recognition unit is used for recognizing an antibody region of the detection test paper, generating image information I and image information II, transmitting the image information I to the processing module and transmitting the image information II to the gray level conversion unit;
and the gray level conversion unit is used for receiving the image information II, then carrying out gray level processing on the image information to obtain gray level image information and transmitting the gray level image information to the processing module.
5. The immunochromatographic assay detection system according to claim 4, wherein the image recognition unit recognizes the antibody region by the method comprising the steps of:
z1: establishing a first coordinate system in advance, establishing edge simulation information of the detection test paper according to the size information of the detection test paper, matching any end of the edge simulation information with the origin of coordinates of the first coordinate system, generating position information in the first coordinate system, marking one end of the edge simulation information matched with the origin of the first coordinate system as H1, and marking an antibody area of the detection test paper in the first coordinate system as K1 according to the edge simulation information;
z2: identifying the edge information of the test paper to be detected, generating edge information I to be identified, comparing the edge information I to be identified with edge simulation information to obtain end point information H2 matched with a first coordinate system, simultaneously matching the edge information I to be identified with the first coordinate system based on the end point information H2, generating an antibody area to be identified marked as K2 based on a K1 area by the edge information I to be identified,
z3: the image recognition unit recognizes the corresponding image information I in the K2 area and copies the image information I to obtain image information II.
6. The method of claim 1, comprising the steps of:
the method comprises the following steps: installing a plurality of groups of samples into a box body, and installing the detection test paper into each detection position module based on the classification sequence of the plurality of groups of samples;
step two: the image detection module identifies the antibody region of each detection test paper, starts the moving module in each detection channel, and moves the separation module to form a corresponding channel I or channel II;
step three: the driving module and the detection position module drive the detection test paper to incline and then contact with the sample, the detection test paper is separated from the sample after the contact, the detection test paper is kept to incline at the same angle for S, and then the detection position module drives the detection test paper to incline in the opposite direction;
step four: the image detection module and the detection test paper rotate at the same angle, and the identified image information is transmitted to the processing module;
step five: the processing module obtains detection data based on the image information.
7. The detection method of the immunochromatographic assay detection system according to claim 6, wherein the value of S in the third step is based on the fluidity of a sample, and the value of S ranges from 0.5S to 3.5S.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202210560647.4A CN114965995B (en) | 2022-05-20 | 2022-05-20 | Immunochromatography analysis detection system and method |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202210560647.4A CN114965995B (en) | 2022-05-20 | 2022-05-20 | Immunochromatography analysis detection system and method |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN114965995A CN114965995A (en) | 2022-08-30 |
| CN114965995B true CN114965995B (en) | 2023-04-11 |
Family
ID=82984913
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202210560647.4A Active CN114965995B (en) | 2022-05-20 | 2022-05-20 | Immunochromatography analysis detection system and method |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN114965995B (en) |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN214472760U (en) * | 2020-11-10 | 2021-10-22 | 河南先邦科技有限公司 | Multi-channel myocardial infarction marker determinator for instant examination |
| CN113567697A (en) * | 2021-07-26 | 2021-10-29 | 四川新健康成生物股份有限公司 | Full-automatic chemiluminescence immunoassay analyzer |
| CN113624973A (en) * | 2021-07-09 | 2021-11-09 | 上海市农产品质量安全中心 | Rapid detection method of alternaria alternate toxin by fluorescence immunochromatography |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR100306951B1 (en) * | 1995-12-05 | 2001-11-15 | 테칸 보스턴, 인코포레이티드 | Devices and method for using centripetal acceleration to drive fluid movement in a microfluidics system with on-board informatics |
| CN101970111B (en) * | 2007-06-21 | 2013-09-11 | 简·探针公司 | Instrument and receptacles for performing processes |
| CN101683648A (en) * | 2008-09-26 | 2010-03-31 | 三星科技股份有限公司 | Sorting machine with reflecting mirrors |
| MX337943B (en) * | 2011-05-18 | 2016-03-29 | Focus Diagnostics Inc | Systems and methods for detecting the presence of a selected volume of material in a sample processing device. |
| DE202012004404U1 (en) * | 2012-05-03 | 2012-06-11 | Euroimmun Medizinische Labordiagnostika Ag | Test kit for laboratory diagnostics |
| CN110437975B (en) * | 2013-10-22 | 2023-06-09 | 伯克利之光生命科技公司 | Microfluidic device with isolated pens and method of testing biological micro-objects using same |
| CN207232178U (en) * | 2017-09-26 | 2018-04-13 | 广州蓝勃生物科技有限公司 | A kind of immunochromatography reagent card is drawn and steering mechanism |
| WO2019108453A1 (en) * | 2017-11-28 | 2019-06-06 | Coopersurgical, Inc. | Specimen containers and related methods |
| CN109490535B (en) * | 2018-10-22 | 2022-03-25 | 湖北洁源检测有限公司 | Multichannel synchronous immunochromatography detection system and detection method |
| CN110221054B (en) * | 2019-04-23 | 2024-02-23 | 深圳市易瑞生物技术股份有限公司 | High-flux automatic chromatographic detection equipment |
| CN210181047U (en) * | 2019-07-04 | 2020-03-24 | 张玉芹 | Immunoassay test examination sampling tube |
| CN111060706A (en) * | 2020-01-17 | 2020-04-24 | 深圳市活水床旁诊断仪器有限公司 | Immunochromatography detection module |
| CN211697835U (en) * | 2020-03-25 | 2020-10-16 | 厦门斯坦道科学仪器股份有限公司 | Detection apparatus for multichannel advances detection sample automatically |
| CN112611751A (en) * | 2020-11-27 | 2021-04-06 | 刘艳娟 | Intelligent urine analyzer |
| CN113156109A (en) * | 2021-03-16 | 2021-07-23 | 广州埃克森生物科技有限公司 | Multifunctional immune quantitative analyzer and implementation method thereof |
| CN113324965A (en) * | 2021-07-02 | 2021-08-31 | 禾柏(南京)医学科技有限公司 | Portable detection device and method based on fluorescent test paper tape |
| CN215449308U (en) * | 2021-09-15 | 2022-01-07 | 王欢 | Neonate blood type and hemolytic disease comprehensive detection device |
-
2022
- 2022-05-20 CN CN202210560647.4A patent/CN114965995B/en active Active
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN214472760U (en) * | 2020-11-10 | 2021-10-22 | 河南先邦科技有限公司 | Multi-channel myocardial infarction marker determinator for instant examination |
| CN113624973A (en) * | 2021-07-09 | 2021-11-09 | 上海市农产品质量安全中心 | Rapid detection method of alternaria alternate toxin by fluorescence immunochromatography |
| CN113567697A (en) * | 2021-07-26 | 2021-10-29 | 四川新健康成生物股份有限公司 | Full-automatic chemiluminescence immunoassay analyzer |
Also Published As
| Publication number | Publication date |
|---|---|
| CN114965995A (en) | 2022-08-30 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US11035870B2 (en) | Systems, methods and apparatus for identifying a specimen container cap | |
| US11954925B2 (en) | Substance preparation evaluation system | |
| JP2022172405A (en) | System and method for multiplex analysis | |
| JP2022084853A (en) | System and method for multiple analysis | |
| US20190033209A1 (en) | Methods and apparatus adapted to quantify a specimen from multiple lateral views | |
| JP2019510963A (en) | Method and apparatus for multiview characterization | |
| BR0001587A (en) | Integrated instrument system for automated nucleic acid analysis, and processes for performing nucleic acid analysis, and diagnostics for collecting data from a test sample that contains one or more nucleic acid sequences in an automated instrument | |
| JP7012746B2 (en) | Label correction method and equipment during sample evaluation | |
| ATE515014T1 (en) | AIR TRAFFIC CONTROL | |
| Bates et al. | Rapid infectious diseases diagnostics using Smartphones | |
| HUP0101655A2 (en) | Process for evaluating chemical and biological assays | |
| CN114965995B (en) | Immunochromatography analysis detection system and method | |
| CN100470578C (en) | Science instrument working state monitoring method based on computer vision | |
| US20180372768A1 (en) | Methods of Automatized Sample Loading and Processing and Devices and Systems Related Thereto | |
| WO2019040894A9 (en) | Substance dispense system for biological sample analysis instrument | |
| EP1329687A3 (en) | An improved optical dilatometer | |
| WO2022174239A1 (en) | Methods and apparatus adapted to identify 3d center location of a specimen container using a single image capture device | |
| WO2022104083A3 (en) | Apparatus and methods for assaying a liquid sample | |
| CN112016387A (en) | Contraband identification method and device suitable for millimeter wave security check instrument | |
| CN113130008A (en) | Test result determination method and device | |
| CN110243823A (en) | The automatic screening apparatus of Rickets and its application method based on support vector machines | |
| Nasr et al. | Usability Evaluation Methods of Indoor Navigation Apps for People with Disabilities: A Scoping Review | |
| KR970066566A (en) | Method and apparatus for extracting connection area of B scope image | |
| CN110458228A (en) | A kind of hazardous material detection method of information source number time-varying and self-adaptive blind source separation | |
| Rodrigues et al. | Identification of Klebsiella pneumoniae complex members using MALDI-TOF mass spectrometry |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| TA01 | Transfer of patent application right | ||
| TA01 | Transfer of patent application right |
Effective date of registration: 20230309 Address after: Room 816, 8th floor, Jinyuan Building, No.8 courtyard, Jinshui Road, Jinshui District, Zhengzhou City, Henan Province, 450000 Applicant after: Henan Shenyou medical laboratory Co.,Ltd. Address before: 100000 building 401, yard 28, Guangqu Road, Chaoyang District, Beijing (No. 4003, Jinsong incubator) Applicant before: Beijing hezicheng Technology Co.,Ltd. |
|
| GR01 | Patent grant | ||
| GR01 | Patent grant |