CN114839798A - Structural color contact lens based on thin film photonic crystal and preparation method thereof - Google Patents
Structural color contact lens based on thin film photonic crystal and preparation method thereof Download PDFInfo
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- G—PHYSICS
- G02—OPTICS
- G02C—SPECTACLES; SUNGLASSES OR GOGGLES INSOFAR AS THEY HAVE THE SAME FEATURES AS SPECTACLES; CONTACT LENSES
- G02C7/00—Optical parts
- G02C7/02—Lenses; Lens systems ; Methods of designing lenses
- G02C7/04—Contact lenses for the eyes
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29D—PRODUCING PARTICULAR ARTICLES FROM PLASTICS OR FROM SUBSTANCES IN A PLASTIC STATE
- B29D11/00—Producing optical elements, e.g. lenses or prisms
- B29D11/00009—Production of simple or compound lenses
- B29D11/00038—Production of contact lenses
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29D—PRODUCING PARTICULAR ARTICLES FROM PLASTICS OR FROM SUBSTANCES IN A PLASTIC STATE
- B29D11/00—Producing optical elements, e.g. lenses or prisms
- B29D11/00865—Applying coatings; tinting; colouring
- B29D11/00894—Applying coatings; tinting; colouring colouring or tinting
- B29D11/00903—Applying coatings; tinting; colouring colouring or tinting on the surface
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29D—PRODUCING PARTICULAR ARTICLES FROM PLASTICS OR FROM SUBSTANCES IN A PLASTIC STATE
- B29D11/00—Producing optical elements, e.g. lenses or prisms
- B29D11/00865—Applying coatings; tinting; colouring
- B29D11/00923—Applying coatings; tinting; colouring on lens surfaces for colouring or tinting
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- C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
- C08J7/00—Chemical treatment or coating of shaped articles made of macromolecular substances
- C08J7/04—Coating
- C08J7/042—Coating with two or more layers, where at least one layer of a composition contains a polymer binder
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- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
- C08J7/00—Chemical treatment or coating of shaped articles made of macromolecular substances
- C08J7/04—Coating
- C08J7/06—Coating with compositions not containing macromolecular substances
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- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
- C08J7/00—Chemical treatment or coating of shaped articles made of macromolecular substances
- C08J7/04—Coating
- C08J7/06—Coating with compositions not containing macromolecular substances
- C08J7/065—Low-molecular-weight organic substances, e.g. absorption of additives in the surface of the article
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- G—PHYSICS
- G02—OPTICS
- G02C—SPECTACLES; SUNGLASSES OR GOGGLES INSOFAR AS THEY HAVE THE SAME FEATURES AS SPECTACLES; CONTACT LENSES
- G02C7/00—Optical parts
- G02C7/02—Lenses; Lens systems ; Methods of designing lenses
- G02C7/04—Contact lenses for the eyes
- G02C7/049—Contact lenses having special fitting or structural features achieved by special materials or material structures
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- G—PHYSICS
- G02—OPTICS
- G02C—SPECTACLES; SUNGLASSES OR GOGGLES INSOFAR AS THEY HAVE THE SAME FEATURES AS SPECTACLES; CONTACT LENSES
- G02C7/00—Optical parts
- G02C7/10—Filters, e.g. for facilitating adaptation of the eyes to the dark; Sunglasses
- G02C7/104—Filters, e.g. for facilitating adaptation of the eyes to the dark; Sunglasses having spectral characteristics for purposes other than sun-protection
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Abstract
The invention relates to the technical field of contact lenses, and particularly discloses a structural color contact lens based on a thin-film photonic crystal and a preparation method thereof, wherein an iris region and/or a pupil region of the contact lens contain a photonic crystal structure, and the photonic crystal structure forms structural color in the contact lens; the contact lens comprises a contact lens substrate and a film formed on an iris area and/or a pupil area of the contact lens substrate, wherein the film is formed on a convex surface and/or a concave surface of the contact lens substrate; the photonic crystal structure is composed of a thin film. The preparation method provided by the invention has the advantages that no additional chemical auxiliary agent is added, the preparation process is simple and efficient, the controllability is strong, the yield is high, the safety of the prepared contact lens is high, the light transmittance is good, and the contact lens is suitable for being worn by a human body.
Description
Technical Field
The invention belongs to the technical field of contact lenses, and particularly relates to a structural color contact lens based on a thin film photonic crystal and a preparation method thereof.
Background
With the rapid improvement of living standard, people no longer simply pursue practicability but more pursue beauty and safety for glasses, wherein contact lenses have been rapidly developed in the past decades, the market share has increased to more than 1.4 hundred million people, and the contact lenses become a symbol that people pursue to see outside the world and have both beauty and convenience. Cosmetic lenses (also known as "cosmetic pupils"), originally introduced by hadens for asian markets, are becoming increasingly popular with beauty loved individuals by adding pigments or pigments to contact lenses to make the eye look like a change in corneal color, thereby making it more attractive.
In the prior art, there are two problems with beautiful pupil products: firstly, the added pigment or pigment is easy to cause discomfort (such as foreign body sensation, congestion, fatigue, secretion and other symptoms) of the cornea of a human body, and even causes anaphylactic reaction of a patient seriously and further causes infection; secondly, the color of the beautiful pupil on the market is single at present, and the requirement of people on multicolor beautiful pupils cannot be met. Recently, Shen et al reported a novel method of making structured color contact lenses: the polymer colloid particles with the core-shell structure are introduced into the Contact lens to form an opal photonic crystal structure, and the prepared Contact lens can present gorgeous Structural color (Shen, X., Du, J., Sun, J., Guo, J., Hu, X., & Wang, C. (2020). However, the use of chemically synthesized polymeric microspheres has two problems: firstly, the colloid particles are easy to form defects in the self-assembly process, the quality of structural color is influenced, the mass preparation is difficult, the cost is reduced, and the reliability and the safety of the obtained structural color contact lenses cannot be guaranteed; secondly, the refractive index of the colloidal particles is different from that of the contact lens base material, so that the light transmittance of the contact lens is influenced, and the practicability is reduced particularly in the scene of insufficient light. Therefore, the development of new structural color contact lens materials is particularly urgent.
Disclosure of Invention
In view of the above, the present invention provides a structural color contact lens based on a thin film photonic crystal and a method for preparing the same. According to the invention, a single-layer or multi-layer film is constructed on the contact lens base material, and the optical path difference is caused by the refractive index difference, so that a photonic crystal structure is generated on the surface of the contact lens to form a structural color.
In order to achieve the purpose, the technical scheme of the invention is as follows:
in one aspect, the present invention provides a thin film photonic crystal based structural color contact lens, the iris and/or pupil regions of the contact lens containing a photonic crystal structure that creates a structural color in the contact lens;
the contact lens comprises a contact lens substrate and a film formed on an iris region and/or a pupil region of the contact lens substrate, wherein the film is formed on a convex surface and/or a concave surface of the contact lens substrate; the photonic crystal structure is composed of the thin film.
Preferably, the film is selected from any one of a polymer film, a metal oxide film, a polyelectrolyte film, a ceramic film, a metal film, and an alloy film;
preferably, the polymer is selected from the group consisting of polymethyl methacrylate, polyhydroxyethyl methacrylate, poly-2-hydroxypropyl methacrylate, polyethoxyethyl methacrylate, polyhydroxypropyl methylcellulose, polyhydroxymethylcellulose, dimethylaminoethyl methacrylate, polyethylene glycol dimethacrylate, isobornyl methacrylate, cellulose acetate butyrate, polysiloxane methacrylate, fluorosilicone methacrylate, polyperfluoroether, poly-N-vinylpyrrolidone, polyvinyl alcohol, polyglycidyl methacrylate, colloidal silica, polyoxyethylene, polydimethylsiloxane, parylene, polylactic acid, polyethylene glycol, polypropylene oxide, polycaprolactone-polyacrylic acid, polylactide, poly (lactide-glycolide), polyacrylamide, poly-N-isopropylacrylamide, poly (hydroxyethyl methacrylate), poly (2-hydroxypropyl methacrylate), poly (ethoxyethyl methacrylate), poly (N-vinylpyrrolidinone), poly (ethylene glycol methacrylate), poly (propylene oxide), poly (caprolactone-poly (caprolactone) -poly (propylene-co-propylene oxide), poly (propylene oxide) -co, Any one or more of choline, hyaluronic acid, collagen, gelatin, guar gum, polyphosphazene, sodium alginate, chitosan, hyaluronic acid, alginic acid, cellulose, agarose, polydextrose, polyamino acid, and fibrin;
The polyamino acid includes poly L-lysine, poly L-glutamic acid, etc.;
preferably, the metal oxide is selected from at least one of oxides of iron, cobalt, nickel, titanium, magnesium, chromium, strontium, manganese, neodymium, cerium, lanthanum, and praseodymium;
preferably, the polyelectrolyte is selected from at least one of polyacrylic acid, polymethacrylic acid, polystyrenesulfonic acid, polyvinylsulfonic acid, polyvinylphosphoric acid, polyethyleneimine, polyvinylamine, polyvinylpyridine, polyphosphate and polysilicate;
preferably, the ceramic is selected from at least one of silicon nitride, alumina, silicon carbide, boron nitride and zirconia ceramics;
preferably, the metal is selected from at least one of iron, gold, copper, silver, titanium, magnesium, zinc, calcium, yttrium, neodymium, zirconium, scandium, gadolinium, erbium, tantalum, niobium, molybdenum, cobalt, chromium and tin;
preferably, the alloy is selected from alloys consisting of any of iron, gold, copper, silver, titanium, magnesium, zinc, calcium, yttrium, neodymium, zirconium, scandium, gadolinium, erbium, tantalum, niobium, molybdenum, cobalt, chromium and tin.
Preferably, the total thickness of the thin film is 1nm to 100 μm. In certain specific embodiments, the thin film has a thickness of 1nm, 100nm, 1 μm, 10 μm, 100 μm, or any thickness therebetween.
Preferably, the number of layers of the film is 1 to 100.
In certain embodiments, the number of layers of the film is 1, 10, 20, 30, 40, 50, 60, 70, 80, 90, 100, or any number therebetween.
The structural color contact lens based on the thin film photonic crystal has the following advantages:
1. the single-layer or multi-layer periodic medium film is covered on the surface of the contact lens, so that optical path difference is generated, a stable structural color is formed, and the contact lens is safe and reliable to a human body;
2. the contact lens provided by the invention has a single layer or multiple layers of films with different refractive indexes from those of the contact lens base material, so that structural color is generated, the pupil can be beautified while the vision is corrected, and meanwhile, the film structure can block part of light in a wavelength band harmful to human eyes, so that the long-term health of the cornea is guaranteed;
3. the contact lens provided by the invention introduces the single-layer multilayer film as a photonic crystal structure, so that the thickness of the film can be changed along with the change of the intraocular environment, the structural color is changed, and the contact lens has the characteristic of changeable structural color.
In another aspect, the present invention provides a method for preparing the above structural color contact lens based on thin film photonic crystals, comprising the following steps:
(1) Adding the precursor solution of the contact lens into a contact lens mold, and polymerizing and curing to obtain a contact lens primary piece;
(2) spin coating an adhesion promoter on the convex surface and/or the concave surface of the primary contact lens obtained in the step (1), and then performing post-treatment to form a thin film and generate structural color; or, carrying out post-treatment on the convex surface and/or the concave surface of the primary contact lens obtained in the step (1) to form a film, so as to generate structural color;
(3) and (3) soaking the contact lens primary sheet containing the film obtained in the step (2) in saline water until the expansion rate is stable and unchanged, thus obtaining the structural color contact lens based on the film photonic crystal.
Preferably, the material of the contact lens mold is selected from any one of glass, quartz, polypropylene, polystyrene, polyethylene terephthalate and polycarbonate.
Preferably, in step (1), the contact lens precursor solution is selected from (a) a solution comprising a polymer; or, (b) a polymerization solution comprising a polymer monomer, an initiator, and a crosslinking agent;
preferably, the polymer is selected from the group consisting of polymethyl methacrylate, polyhydroxyethyl methacrylate, poly-2-hydroxypropyl methacrylate, polyethoxyethyl methacrylate, polyhydroxypropyl methylcellulose, polyhydroxymethylcellulose, dimethylaminoethyl methacrylate, polyethylene glycol dimethacrylate, isobornyl methacrylate, cellulose acetate butyrate, polysiloxane methacrylate, fluorosilicone methacrylate, polyperfluoroether, poly-N-vinylpyrrolidone, polyvinyl alcohol, polyglycidyl methacrylate, colloidal silica, polyoxyethylene, polydimethylsiloxane, parylene, polylactic acid, polyethylene glycol, polypropylene oxide, polycaprolactone-polyacrylic acid, polylactide, poly (lactide-glycolide), polyacrylamide, poly-N-isopropylacrylamide, poly (hydroxyethyl methacrylate), poly (2-hydroxypropyl methacrylate), poly (ethoxyethyl methacrylate), poly (N-vinylpyrrolidinone), poly (ethylene glycol methacrylate), poly (propylene oxide), poly (caprolactone-poly (caprolactone) -poly (propylene-co-propylene oxide), poly (propylene oxide) -co, Any one or any several of copolymer of choline, hyaluronic acid, collagen, gelatin, guar gum, polyphosphazene, sodium alginate, chitosan, hyaluronic acid, alginic acid, cellulose, agarose, polydextrose polyamino acid and fibrin;
Examples of the polyamino acid include poly-L-lysine and poly-L-glutamic acid.
In certain specific embodiments, the initiator is selected from any one of inorganic peroxide initiators including, but not limited to, ammonium persulfate, sodium persulfate, potassium persulfate; the azo initiator includes, but is not limited to, azobisisobutyronitrile, azobisisoheptonitrile; the peroxide initiator includes but is not limited to benzoyl peroxide, cyclohexanone peroxide; the photoinitiator includes but is not limited to diethoxyacetophenone, 2-hydroxy-4- (2-hydroxyethoxy) -2-methylpropiophenone, and phenyl bis (2,4, 6-trimethylbenzoyl) phosphine oxide.
Preferably, the crosslinking agent is selected from at least one of methylene bisacrylamide, ethylene glycol dimethacrylate, polyethylene glycol dimethacrylate, divinylbenzene and derivatives thereof.
Preferably, in the step (2), the adhesion promoter is selected from any one of titanate coupling agent, silane coupling agent, zirconium aluminate coupling agent, isocyanate coupling agent, amide coupling agent and epoxy coupling agent.
Preferably, in the step (2), the post-treatment method is one or more selected from ion sputtering deposition, vapor deposition, vacuum sputtering coating, spin-on film formation, casting film formation and ion beam evaporation deposition.
In the technical scheme of the invention, the film formed by the post-treatment can be any one of a polymer film, a metal oxide film, a polyelectrolyte film, a ceramic film and a metal film.
Preferably, in the step (3), the brine is selected from any one of a sodium chloride aqueous solution with a mass fraction of 0.1-10.0%, a sodium dihydrogen phosphate aqueous solution with a mass fraction of 0.1-10.0%, and a disodium hydrogen phosphate aqueous solution with a mass fraction of 0.1-10.0%.
Specifically, a contact lens precursor containing a single or multi-layer film is immersed in saline at a pH of 5.0 to 9.0 for 2 to 24 hours.
Preferably, in the step (2), the total thickness of the thin film is 1nm to 100 μm.
In certain specific embodiments, the thin film has a thickness of 1nm, 100nm, 1 μm, 10 μm, 100 μm, or any thickness therebetween.
Preferably, in the step (2), the number of layers of the film is 1 to 100.
In certain embodiments, the number of layers of the film is 1, 10, 20, 30, 40, 50, 60, 70, 80, 90, 100, or any number therebetween.
According to the technical scheme, after post-treatment is carried out on the primary contact lens piece obtained after polymerization and solidification, metal oxide and other raw materials capable of being used as contact lenses are compounded with a single-layer or multi-layer film on the surface of the primary contact lens piece, the refractive index of the film is different from that of the primary contact lens piece, the film is matched with the wavelength of visible light to generate optical path difference, and a photonic crystal structure is formed, so that the contact lens with structural color is prepared.
According to the preparation method of the film photonic crystal-based structural color contact lens, provided by the invention, the optical path difference is generated by forming the multilayer film on the surface of the lens, so that the photonic crystal structure with structural color is formed, and compared with the prior art, the preparation method has the following advantages:
1. the invention adopts the common preparation materials of the contact lenses as raw materials, and the prepared contact lenses have high transparency, form structural color, ensure light transmittance and still can be normally used under the condition of insufficient light.
2. The photonic crystal microstructure is formed by a film forming technology, and compared with the existing self-assembly method and film processing method, the photonic crystal microstructure has the advantages of better safety, stronger controllability and high yield, and the photonic crystal structure obtained by the method has fewer defects.
3. The single-layer or multi-layer film provided by the invention is manufactured by unidirectional additive manufacturing, is easier to control compared with a colloid multi-layer self-assembly method, has a simple process, does not need additional chemical solvent, and is suitable for wearing.
Drawings
Fig. 1 is a schematic view of the contact lens structure of example 1.
FIG. 2 is a schematic view of the contact lens according to example 3.
Detailed Description
The following examples are only a part of the present invention, and not all of them. Thus, the detailed description of the embodiments of the present invention provided below is not intended to limit the scope of the invention as claimed, but is merely representative of selected embodiments of the invention. All other embodiments, which can be derived by a person skilled in the art from the embodiments of the invention without making creative efforts, belong to the protection scope of the invention.
Example 1
The process for preparing a structural color contact lens based on a thin film photonic crystal in the embodiment comprises the following steps:
(1) Taking a polycarbonate contact lens mould, wherein the mould comprises an upper mould and a lower mould which can be separated, the upper mould is provided with a convex spherical surface, the lower mould is provided with a concave spherical surface, and a contact lens prepolymer solution is added into the mould: adding 2, 2-diethoxyacetophenone (the mass is 0.5 percent of methylene bisacrylamide) serving as an initiator into a contact lens mold in a mass ratio of hydroxyethyl methacrylate to methylene bisacrylamide (50: 1), and curing for 30min by 365nm ultraviolet light to obtain a contact lens primary sheet;
(2) coating zirconium aluminate coupling agent with the thickness of 1 mu m on the surface of the obtained contact lens primary piece, putting the contact lens primary piece into a vacuum coating machine, and evaporating a single-layer gold film on the contact lens primary piece on the convex spherical surface side to obtain the contact lens primary piece of the composite film.
(3) And (3) placing the contact lens primary piece of the composite film in a sodium chloride aqueous solution with the pH value of 7.3 and the mass fraction of 0.89% to soak until the swelling rate is stable.
The contact lens structure in this embodiment is shown in fig. 1: the contact lens comprises a contact lens, a pupil area I, an iris area II, a photonic crystal structure, a film and a color element, wherein the pupil area I and the iris area II are arranged in the contact lens, the photonic crystal structure is a film which is uniformly distributed, the thickness of the film is 30 mu m, and the color of the photonic crystal structure is distributed on the outer convex surface and/or the inner concave surface of the contact lens as the color element. In this embodiment, the film can be laminated to the pupil region I and/or the iris region II of the contact lens by selecting different molds.
Example 2
The process for preparing a structural color contact lens based on a thin film photonic crystal in the embodiment comprises the following steps:
(1) taking a polypropylene contact lens mould, wherein the mould comprises an upper mould and a lower mould which can be separated, the upper mould is provided with a convex spherical surface, the lower mould is provided with a concave spherical surface, and a contact lens prepolymer solution is added into the mould: adding methyl methacrylate into a contact lens mold by taking 2-hydroxy-2-methyl-1-phenyl-1-acetone (photo nitator 1173, the mass of which is 0.2 percent of that of the methyl methacrylate) as an initiator, and curing for 30min by 254nm ultraviolet light to obtain a contact lens primary piece;
(2) and coating a silane coupling agent with the thickness of 3 mu m on the surface of the obtained contact lens primary piece, performing chemical vapor deposition, and depositing a silicon nitride film on the contact lens primary piece on the outer convex surface side and the inner concave surface side to obtain the contact lens primary piece of the composite film.
(3) And (3) placing the contact lens primary piece of the composite film in a sodium chloride aqueous solution with the pH value of 7.3 and the mass fraction of 0.89% to soak until the swelling rate is stable.
The contact lens obtained in the embodiment contains a photonic crystal structure, the photonic crystal structure is a uniform film with periodic arrangement, the thickness of the film is 50 μm, and the color of the photonic crystal structure is distributed in the contact lens as a color element.
Example 3
The process for preparing a structural color contact lens based on a thin film photonic crystal in the embodiment comprises the following steps:
(1) taking a polymethyl methacrylate contact lens mould, wherein the mould comprises an upper mould and a lower mould which can be separated, the upper mould is provided with a convex spherical surface, the lower mould is provided with a concave spherical surface, and a contact lens prepolymer solution is added into the mould: mixing Polydimethylsiloxane (PDMS) and silicon rubber (Sylgard 184B as a curing agent) according to a mass ratio of 10:1, mixing the mixed solution with normal hexane according to a volume ratio of 1:1 to serve as a contact lens prepolymer for later use, adding 150 microliters of prepolymer solution into a contact lens mold, and performing thermocuring at 50 ℃ for 120min to obtain a contact lens primary sheet;
(2) the surface of the obtained contact lens primary piece is coated with an isocyanate coupling agent with the thickness of 10 mu m, the obtained contact lens primary piece is subjected to spin coating, and a polystyrene-polyvinylpyridine (PS-b-P4VP) film is spin-coated on the contact lens primary piece on the outer convex surface side and the inner concave surface side, so that the contact lens primary piece of a composite film with the thickness of 300nm is obtained.
(3) The initial contact lens piece of the composite film is further spin-coated, the steps are the same as those in the step (2), the multilayer block copolymer film can be compounded, the structural color of the photonic crystal contact lens is more obvious, and the structural color effect is still achieved after 100 layers of the film are coated.
(4) The initial contact lens piece of the composite multilayer block copolymer film is placed in a sodium chloride aqueous solution with the pH value of 7.3 and the mass fraction of 0.1 percent to be soaked until the expansion rate is stable and unchanged.
The contact lens obtained in the embodiment contains a photonic crystal structure, the photonic crystal structure is a uniform film with periodic arrangement, structural colors can be observed when the number of layers of the film is in the range of 1-100, the corresponding thickness range of the film is 300nm-30 mu m, and the structural colors of the photonic crystal are distributed on the outer convex surface and the inner concave surface of the contact lens as color elements. In the present embodiment, the contact lens structure is shown in fig. 2, and the film can be laminated to the pupil area I and/or iris area II of the contact lens by selecting different molds.
Example 4
The process for preparing a structural color contact lens based on a thin film photonic crystal in the embodiment comprises the following steps:
(1) taking a contact lens mold made of polystyrene material, wherein the mold comprises an upper mold and a lower mold which can be separated, the upper mold is provided with a convex spherical surface, the lower mold is provided with a concave spherical surface, and a contact lens prepolymer solution is added into the mold: adding polyvinyl alcohol and polyethylene glycol diacrylate (mass ratio is 40:1) into a contact lens mold by taking 2-hydroxy-4- (2-hydroxyethoxy) -2-methyl propiophenone (Irgacure 2959) (the mass is 0.2% of the polyvinyl alcohol) as an initiator, and curing for 30min by 365nm ultraviolet light to obtain a contact lens primary sheet;
(2) And spin-coating an amide coupling agent with the thickness of 20 mu m on the surface of the obtained contact lens primary piece, carrying out vacuum sputtering deposition on the obtained contact lens primary piece, and carrying out vacuum deposition on a titanium dioxide film ion beam on the contact lens primary piece on the outer convex surface side and the inner concave surface side to obtain the contact lens primary piece of the composite film.
(3) And (3) carrying out secondary deposition on the primary contact lens of the composite film, wherein the steps are the same as those in the step (2), so that a plurality of layers of titanium dioxide films can be compounded, and the structural color of the photonic crystal contact lens is more obvious.
(4) The initial contact lens piece of the composite multilayer titanium dioxide film is placed in a sodium chloride aqueous solution with the pH value of 5.0 and the mass fraction of 10.0 percent to be soaked until the expansion rate is stable and unchanged.
The contact lens obtained in the embodiment contains a photonic crystal structure, wherein the photonic crystal structure is a uniform film with periodic arrangement, has the thickness of 20 μm, and is distributed in the contact lens as a color element.
Example 5
The process for preparing a structural color contact lens based on a thin film photonic crystal in the embodiment comprises the following steps:
(1) taking a contact lens mold made of polystyrene material, wherein the mold comprises an upper mold and a lower mold which can be separated, the upper mold is provided with a convex spherical surface, the lower mold is provided with a concave spherical surface, and a contact lens prepolymer solution is added into the mold: adding glycidyl methacrylate and ethylene glycol dimethacrylate (mass ratio is 20:1) into a contact lens mould by taking phenyl bis (2,4, 6-trimethylbenzoyl) phosphine oxide (Photonititor 819, mass is 0.2 percent of the glycidyl methacrylate) as an initiator, and curing for 30min by 365nm ultraviolet light to obtain a contact lens primary sheet;
(2) Fixing the initial contact lens piece, and carrying out tape casting film formation on the polycarbonate prepolymer on the initial contact lens piece on the outer convex surface side and the inner concave surface side to obtain the initial contact lens piece of the composite film, wherein the thickness of the initial contact lens piece is 10 micrometers.
(3) The contact lens primary piece of the composite film is subjected to secondary deposition, the steps are the same as those in the step (2), a multilayer polymer film can be compounded, the structural color of the photonic crystal contact lens is more obvious, and the contact lens still has the structural color after 20 layers of polymer films are compounded.
(4) And (3) placing the contact lens primary piece of the composite multilayer polycarbonate film in a sodium chloride aqueous solution with the pH value of 9.0 and the mass fraction of 0.89% to soak until the swelling rate is stable.
The contact lens obtained in the embodiment contains a photonic crystal structure, the photonic crystal structure is a uniform film with periodic arrangement, the thickness of the film is 10-200 μm, and the color of the photonic crystal structure is distributed in the contact lens as a color element.
Example 6
The process for preparing a structural color contact lens based on a thin film photonic crystal in the embodiment comprises the following steps:
(1) taking a contact lens mold made of polystyrene material, wherein the mold comprises an upper mold and a lower mold which can be separated, the upper mold is provided with a convex spherical surface, the lower mold is provided with a concave spherical surface, and a contact lens prepolymer solution is added into the mold: adding cellulose acetate butyrate serving as a monomer and 2-hydroxy-4- (2-hydroxyethoxy) -2-methyl propiophenone (Irgacure 2959) (the mass of the monomer is 1.0%) serving as an initiator into a contact lens mold, and curing for 40min by 365nm ultraviolet light to obtain a contact lens primary sheet;
(2) And spin-coating polystyrene sulfonic acid on the obtained contact lens primary piece, and depositing a polyelectrolyte film on the contact lens primary piece on the outer convex surface side and the inner concave surface side to obtain the contact lens primary piece of the composite film.
(3) And (3) carrying out secondary deposition on the contact lens primary piece of the composite film, wherein the step is the same as the step (2), so that a multilayer polystyrene sulfonic acid film can be compounded, and the structural color of the photonic crystal contact lens is more obvious.
(4) The contact lens primary piece of the composite multilayer polystyrene sulfonic acid film is placed in a sodium chloride aqueous solution with the pH value of 6.0 and the mass fraction of 10.0 percent to be soaked until the expansion rate is stable and unchanged.
The contact lens obtained in the embodiment contains a photonic crystal structure, wherein the photonic crystal structure is a uniform film with periodic arrangement, has the thickness of 40 mu m, and is distributed in the contact lens as a color element.
Example 7
The process for preparing a structural color contact lens based on a thin film photonic crystal in the embodiment comprises the following steps:
(1) taking a contact lens mold made of polystyrene material, wherein the mold comprises an upper mold and a lower mold which can be separated, the upper mold is provided with a convex spherical surface, the lower mold is provided with a concave spherical surface, and a contact lens prepolymer solution is added into the mold: adding a hydroxyethyl methacrylate monomer into a contact lens mold by taking 2-hydroxy-4- (2-hydroxyethoxy) -2-methyl propiophenone (Irgacure 2959) (the mass is 2.0 percent of the block polymer) as an initiator, and curing for 30min by 365nm ultraviolet light to obtain a contact lens primary sheet;
(2) And coating an amide coupling agent with the thickness of 10 mu m on the surface of the obtained contact lens primary piece, carrying out vacuum sputtering deposition on the obtained contact lens primary piece, and carrying out vacuum deposition on a polymethyl methacrylate-b-polymethyl methacrylate 2- (dimethyl bromoethyl) aminoethyl (PMMA-b-PDM) film ion beam on the contact lens primary piece on the outer convex surface side and the inner concave surface side to obtain the contact lens primary piece of the composite film.
(3) And (3) carrying out secondary deposition on the primary contact lens of the composite film, wherein the steps are the same as those in the step (2), so that a plurality of layers of titanium dioxide films can be compounded, and the structural color of the photonic crystal contact lens is more obvious.
(4) The initial contact lens piece of the composite multilayer titanium dioxide film is placed in a sodium chloride aqueous solution with the pH value of 5.0 and the mass fraction of 10.0 percent to be soaked until the expansion rate is stable and unchanged.
The contact lens obtained in the embodiment contains a photonic crystal structure, wherein the photonic crystal structure is a uniform film with periodic arrangement, has the thickness of 100 mu m, and is distributed in the contact lens as a color element.
Example 8
The process for preparing a structural color contact lens based on a thin film photonic crystal in the embodiment comprises the following steps:
(1) taking a contact lens mold made of polystyrene material, wherein the mold comprises an upper mold and a lower mold which can be separated, the upper mold is provided with a convex spherical surface, the lower mold is provided with a concave spherical surface, and a contact lens prepolymer solution is added into the mold: adding polyvinyl alcohol and polyethylene glycol diacrylate (mass ratio is 40:1) into a contact lens mold by taking 2-hydroxy-4- (2-hydroxyethoxy) -2-methyl propiophenone (Irgacure 2959) (the mass is 1.0 percent of the polyvinyl alcohol) as an initiator, and curing for 30min by 365nm ultraviolet light to obtain a contact lens primary sheet;
(2) And coating the surface of the obtained contact lens primary piece with an amide coupling agent with the thickness of 20 mu m, and spin-coating styrene-maleic anhydride copolymer precursor liquid on the outer convex surface side and the inner concave surface side of the obtained contact lens primary piece to obtain the contact lens primary piece of the composite film.
(3) And (3) carrying out secondary deposition on the primary contact lens of the composite film, wherein the steps are the same as those in the step (2), so that a multilayer styrene-maleic anhydride film can be compounded, and the structural color of the photonic crystal contact lens is more obvious.
(4) The initial contact lens piece of the composite multilayer titanium dioxide film is placed in a sodium chloride aqueous solution with the pH value of 5.0 and the mass fraction of 10.0 percent to be soaked until the expansion rate is stable and unchanged.
The contact lens obtained in the embodiment contains a photonic crystal structure, wherein the photonic crystal structure is a uniform film with periodic arrangement, the thickness of the photonic crystal structure is 1nm, and the photonic crystal structure is used as a color element and distributed in the contact lens.
Effects of the embodiment
In order to strongly support the beneficial effects brought by the technical scheme of the embodiment of the invention, the following performance tests are provided:
A. light transmission test
The light transmittance test of the contact lenses with photonic crystal structural colors obtained in the embodiments 1 to 5 shows that the transmittance of white light reaches over 90%.
B. Water content test
The contact lenses having photonic crystal structural colors obtained in examples 1 to 5 of the present invention were subjected to a water content test, and the results showed that the water content thereof was more than 60%.
C. Oxygen permeability test
The oxygen permeability test of the contact lenses with the photonic crystal structural color obtained in the embodiments 1 to 5 shows that the oxygen permeability is as high as 150 Dk/t.
D. Cytotoxicity test
Cytotoxicity test the cytotoxicity test can prepare an objective response to the potential toxicity of the test sample, and the method examines the cytotoxicity of the contact lens according to the IS09363-1 method, in which the cytotoxicity response IS graded on a 0-4 scale, and the lower the scale, the higher the safety of the tested material. The comparative test of cytotoxicity of the contact lens with the photonic crystal structural color obtained in the first to fifth embodiments of the invention and the commercially available Haichang ultrathin contact lens shows that the cytotoxicity of the contact lens with the structural color is0 grade as that of the commercially available Haichang ultrathin contact lens, which indicates that the safety of the contact lens meets the standard of human use.
The above description is only for the preferred embodiment of the present invention and is not intended to limit the scope of the present invention, and all equivalent modifications made by the contents of the present specification and the drawings, or applied directly or indirectly to other related technical fields, are included in the scope of the present invention.
Claims (14)
1. A structural color contact lens based on a thin film photonic crystal, wherein the iris and/or pupil regions of the contact lens contain a photonic crystal structure that creates a structural color in the contact lens;
the contact lens comprises a contact lens substrate and a film formed on an iris region and/or a pupil region of the contact lens substrate, wherein the film is formed on a convex surface and/or a concave surface of the contact lens substrate; the photonic crystal structure is composed of the thin film.
2. The structured color contact lens of claim 1, wherein said film is selected from any one of a polymer film, a metal oxide film, a polyelectrolyte film, a ceramic film, a metal film, and an alloy film;
preferably, the polymer is selected from the group consisting of polymethyl methacrylate, polyhydroxyethyl methacrylate, poly-2-hydroxypropyl methacrylate, polyethoxyethyl methacrylate, polyhydroxypropyl methylcellulose, polyhydroxymethylcellulose, dimethylaminoethyl methacrylate, polyethylene glycol dimethacrylate, isobornyl methacrylate, cellulose acetate butyrate, polysiloxane methacrylate, fluorosilicone methacrylate, polyperfluoroether, poly-N-vinylpyrrolidone, polyvinyl alcohol, polyglycidyl methacrylate, colloidal silica, polyoxyethylene, polydimethylsiloxane, parylene, polylactic acid, polyethylene glycol, polypropylene oxide, polycaprolactone-polyacrylic acid, polylactide, poly (lactide-glycolide), polyacrylamide, poly-N-isopropylacrylamide, poly (hydroxyethyl methacrylate), poly (2-hydroxypropyl methacrylate), poly (ethoxyethyl methacrylate), poly (N-vinylpyrrolidinone), poly (ethylene glycol methacrylate), poly (propylene oxide), poly (caprolactone-poly (caprolactone) -poly (propylene-co-propylene oxide), poly (propylene oxide) -co, Any one or a plurality of copolymers of choline, collagen, gelatin, guar gum, polyphosphazene, sodium alginate, chitosan, hyaluronic acid, alginic acid, cellulose, agarose, polydextrose, polyamino acid and fibrin;
Preferably, the metal oxide is selected from at least one of oxides of iron, cobalt, nickel, titanium, magnesium, chromium, strontium, manganese, neodymium, cerium, lanthanum, and praseodymium;
preferably, the polyelectrolyte is selected from at least one of polyacrylic acid, polymethacrylic acid, polystyrenesulfonic acid, polyvinylsulfonic acid, polyvinylphosphoric acid, polyethyleneimine, polyvinylamine, polyvinylpyridine, polyphosphate and polysilicate;
preferably, the ceramic is selected from at least one of silicon nitride, alumina, silicon carbide, boron nitride and zirconia ceramics;
preferably, the metal is selected from at least one of iron, gold, copper, silver, titanium, magnesium, zinc, calcium, yttrium, neodymium, zirconium, scandium, gadolinium, erbium, tantalum, niobium, molybdenum, cobalt, chromium and tin;
preferably, the alloy is selected from alloys consisting of any of iron, gold, copper, silver, titanium, magnesium, zinc, calcium, yttrium, neodymium, zirconium, scandium, gadolinium, erbium, tantalum, niobium, molybdenum, cobalt, chromium and tin.
3. The structured color contact lens of claim 1, wherein said film has a total thickness of from 1nm to 100 μm.
4. The structured color contact lens of claim 1, wherein the number of layers of said film is from 1 to 100.
5. A method of making a structured color contact lens according to any of claims 1 to 4 comprising the steps of:
(1) adding the precursor solution of the contact lens into a contact lens mold, and polymerizing and curing to obtain a contact lens primary piece;
(2) spin coating an adhesion promoter on the convex surface and/or the concave surface of the primary contact lens obtained in the step (1), and then performing post-treatment to form a thin film and generate structural color; or carrying out post-treatment on the convex surface and/or the concave surface of the primary contact lens obtained in the step (1) to form a film and generate structural color;
(3) and (3) placing the contact lens primary piece containing the film obtained in the step (2) in saline water to be soaked until the expansion rate is stable and unchanged, and obtaining the structural color contact lens based on the film photonic crystal.
6. The method of claim 5, wherein the contact lens mold is made of a material selected from the group consisting of glass, quartz, polypropylene, polystyrene, polyethylene terephthalate, and polycarbonate.
7. The method of claim 5, wherein in step (1), the contact lens precursor solution is selected from the group consisting of (a) a solution comprising a polymer; or, (b) a polymerization solution comprising a polymer monomer, an initiator, and a crosslinking agent;
Preferably, the polymer is selected from the group consisting of polymethyl methacrylate, polyhydroxyethyl methacrylate, poly-2-hydroxypropyl methacrylate, polyethoxyethyl methacrylate, polyhydroxypropyl methylcellulose, polyhydroxymethylcellulose, dimethylaminoethyl methacrylate, polyethylene glycol dimethacrylate, isobornyl methacrylate, cellulose acetate butyrate, polysiloxane methacrylate, fluorosilicone methacrylate, polyperfluoroether, poly-N-vinylpyrrolidone, polyvinyl alcohol, polyglycidyl methacrylate, colloidal silica, polyoxyethylene, polydimethylsiloxane, parylene, polylactic acid, polyethylene glycol, polypropylene oxide, polycaprolactone-polyacrylic acid, polylactide, poly (lactide-glycolide), polyacrylamide, poly-N-isopropylacrylamide, poly (hydroxyethyl methacrylate), poly (2-hydroxypropyl methacrylate), poly (ethoxyethyl methacrylate), poly (N-vinylpyrrolidinone), poly (ethylene glycol methacrylate), poly (propylene oxide), poly (caprolactone-poly (caprolactone) -poly (propylene-co-propylene oxide), poly (propylene oxide) -co, Choline, hyaluronic acid, collagen, gelatin, guar gum, polyphosphazene, sodium alginate, chitosan, hyaluronic acid, alginic acid, cellulose, agarose, polydextrose, polyamino acid and fibrin.
8. The method according to claim 7, wherein the initiator is selected from any one of inorganic peroxide initiators, azo initiators, peroxide initiators and photoinitiators.
9. The method according to claim 7, wherein the crosslinking agent is at least one selected from the group consisting of methylenebisacrylamide, ethylene glycol dimethacrylate, polyethylene glycol dimethacrylate, divinylbenzene and a derivative thereof.
10. The method according to claim 5, wherein in the step (2), the adhesion promoter is selected from any one of a titanate coupling agent, a silane coupling agent, a zirconium aluminate coupling agent, an isocyanate coupling agent, an amide coupling agent, and an epoxy coupling agent.
11. The method according to claim 5, wherein in the step (2), the post-treatment is selected from one or more of ion sputtering deposition, vapor deposition, vacuum sputtering coating, spin-on film formation, casting film formation, and ion beam evaporation deposition.
12. The method according to claim 5, wherein in the step (3), the brine is selected from any one of an aqueous sodium chloride solution having a mass fraction of 0.1% to 10.0%, an aqueous sodium dihydrogen phosphate solution having a mass fraction of 0.1% to 10.0%, and an aqueous disodium hydrogen phosphate solution having a mass fraction of 0.1% to 10.0%.
13. The method according to claim 5, wherein in the step (2), the thickness of the thin film is 1nm to 100 μm.
14. The production method according to claim 5, wherein in the step (2), the number of layers of the film is 1 to 100.
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202210375348.3A CN114839798A (en) | 2022-04-11 | 2022-04-11 | Structural color contact lens based on thin film photonic crystal and preparation method thereof |
| PCT/CN2022/137078 WO2023197631A1 (en) | 2022-04-11 | 2022-12-06 | Thin film photonic crystal-based structural color contact lens and preparation method therefor |
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| Application Number | Priority Date | Filing Date | Title |
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| CN202210375348.3A CN114839798A (en) | 2022-04-11 | 2022-04-11 | Structural color contact lens based on thin film photonic crystal and preparation method thereof |
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| CN114839798A true CN114839798A (en) | 2022-08-02 |
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| CN202210375348.3A Pending CN114839798A (en) | 2022-04-11 | 2022-04-11 | Structural color contact lens based on thin film photonic crystal and preparation method thereof |
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| CN (1) | CN114839798A (en) |
| WO (1) | WO2023197631A1 (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2023197631A1 (en) * | 2022-04-11 | 2023-10-19 | 深圳先进技术研究院 | Thin film photonic crystal-based structural color contact lens and preparation method therefor |
Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102200650A (en) * | 2011-05-19 | 2011-09-28 | 东南大学 | Composite structured colored contact lens |
| CN203037946U (en) * | 2013-01-14 | 2013-07-03 | 河南科技大学 | Photonic crystal ultraviolet protection glasses |
| CN103605215A (en) * | 2013-10-22 | 2014-02-26 | 东南大学 | One-dimensional photonic crystal-based colorful contact lenses and preparation method thereof |
| US20140300857A1 (en) * | 2011-12-08 | 2014-10-09 | Essilor International (Compagnie Generale D'optiqu E) | Ophthalmic filter |
| CN106751604A (en) * | 2016-11-18 | 2017-05-31 | 中国科学院深圳先进技术研究院 | A kind of shape memory photon crystal material and preparation method thereof |
| WO2017131588A1 (en) * | 2016-01-27 | 2017-08-03 | Agency For Science, Technology And Research | Textured surface ophthalmic device |
| US20180267331A1 (en) * | 2017-03-17 | 2018-09-20 | Imam Abdulrahman Bin Faisal University | Contact lens containing a photonic crystal |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20030117576A1 (en) * | 2001-12-05 | 2003-06-26 | Ocular Sciences, Inc. | Colored contact lenses |
| JP6093508B2 (en) * | 2012-03-30 | 2017-03-08 | 尚樹 井村 | contact lens |
| CN103760686B (en) * | 2014-01-15 | 2014-12-03 | 林国义 | Contact lenses with coating films on outer sides and manufacturing method thereof |
| WO2017041085A1 (en) * | 2015-09-04 | 2017-03-09 | President And Fellows Of Harvard College | Modifying optical properties of thin film structures using an absorbing element |
| CN107463001A (en) * | 2017-08-18 | 2017-12-12 | 深圳先进技术研究院 | A kind of schemochrome sun contact lenses and preparation method thereof |
| CN110396211A (en) * | 2018-04-25 | 2019-11-01 | 亨泰光学股份有限公司 | The contact lenses processing method of preparation tool film is grafted using plasma-based induced polymerization |
| CN110879481B (en) * | 2018-09-06 | 2021-04-06 | 凯乐康药业(重庆)股份有限公司 | Anti-dazzle contact lens |
| TWI690424B (en) * | 2018-10-29 | 2020-04-11 | 優你康光學股份有限公司 | Method for preparing contact lens with polymer multilayer film |
| CN114839798A (en) * | 2022-04-11 | 2022-08-02 | 深圳先进技术研究院 | Structural color contact lens based on thin film photonic crystal and preparation method thereof |
-
2022
- 2022-04-11 CN CN202210375348.3A patent/CN114839798A/en active Pending
- 2022-12-06 WO PCT/CN2022/137078 patent/WO2023197631A1/en unknown
Patent Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102200650A (en) * | 2011-05-19 | 2011-09-28 | 东南大学 | Composite structured colored contact lens |
| US20140300857A1 (en) * | 2011-12-08 | 2014-10-09 | Essilor International (Compagnie Generale D'optiqu E) | Ophthalmic filter |
| CN203037946U (en) * | 2013-01-14 | 2013-07-03 | 河南科技大学 | Photonic crystal ultraviolet protection glasses |
| CN103605215A (en) * | 2013-10-22 | 2014-02-26 | 东南大学 | One-dimensional photonic crystal-based colorful contact lenses and preparation method thereof |
| WO2017131588A1 (en) * | 2016-01-27 | 2017-08-03 | Agency For Science, Technology And Research | Textured surface ophthalmic device |
| CN106751604A (en) * | 2016-11-18 | 2017-05-31 | 中国科学院深圳先进技术研究院 | A kind of shape memory photon crystal material and preparation method thereof |
| US20180267331A1 (en) * | 2017-03-17 | 2018-09-20 | Imam Abdulrahman Bin Faisal University | Contact lens containing a photonic crystal |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2023197631A1 (en) * | 2022-04-11 | 2023-10-19 | 深圳先进技术研究院 | Thin film photonic crystal-based structural color contact lens and preparation method therefor |
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