CN114669520B - Blood treatment facility and end cover cleaning device thereof - Google Patents
Blood treatment facility and end cover cleaning device thereof Download PDFInfo
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- CN114669520B CN114669520B CN202210319283.0A CN202210319283A CN114669520B CN 114669520 B CN114669520 B CN 114669520B CN 202210319283 A CN202210319283 A CN 202210319283A CN 114669520 B CN114669520 B CN 114669520B
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- end cover
- cleaning
- end cap
- cleaning device
- thrombus
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- 238000004140 cleaning Methods 0.000 title claims abstract description 110
- 239000008280 blood Substances 0.000 title claims abstract description 33
- 210000004369 blood Anatomy 0.000 title claims abstract description 32
- 208000007536 Thrombosis Diseases 0.000 claims abstract description 31
- 238000000502 dialysis Methods 0.000 claims abstract description 25
- 238000000034 method Methods 0.000 claims abstract description 12
- 239000012528 membrane Substances 0.000 claims abstract description 11
- 230000008569 process Effects 0.000 claims abstract description 9
- 238000007789 sealing Methods 0.000 claims description 13
- 238000012545 processing Methods 0.000 claims description 5
- 239000000463 material Substances 0.000 claims description 3
- 229920002635 polyurethane Polymers 0.000 claims description 3
- 239000004814 polyurethane Substances 0.000 claims description 3
- 229920001296 polysiloxane Polymers 0.000 claims 1
- 230000004872 arterial blood pressure Effects 0.000 description 11
- 230000015572 biosynthetic process Effects 0.000 description 5
- 238000002615 hemofiltration Methods 0.000 description 3
- 238000012544 monitoring process Methods 0.000 description 3
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 2
- 230000017531 blood circulation Effects 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 239000000741 silica gel Substances 0.000 description 2
- 229910002027 silica gel Inorganic materials 0.000 description 2
- 208000001953 Hypotension Diseases 0.000 description 1
- 230000002411 adverse Effects 0.000 description 1
- 238000004458 analytical method Methods 0.000 description 1
- 239000003146 anticoagulant agent Substances 0.000 description 1
- 229940127219 anticoagulant drug Drugs 0.000 description 1
- 230000010100 anticoagulation Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000023555 blood coagulation Effects 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 238000012512 characterization method Methods 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 238000002224 dissection Methods 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 239000012510 hollow fiber Substances 0.000 description 1
- 230000036543 hypotension Effects 0.000 description 1
- 238000000746 purification Methods 0.000 description 1
- NLJMYIDDQXHKNR-UHFFFAOYSA-K sodium citrate Chemical compound O.O.[Na+].[Na+].[Na+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O NLJMYIDDQXHKNR-UHFFFAOYSA-K 0.000 description 1
- 239000001509 sodium citrate Substances 0.000 description 1
- 238000010408 sweeping Methods 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- 239000003053 toxin Substances 0.000 description 1
- 231100000765 toxin Toxicity 0.000 description 1
Images
Classifications
-
- B08B1/12—
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
- A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
- A61M1/1621—Constructional aspects thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
- A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
- A61M1/168—Sterilisation or cleaning before or after use
-
- B08B1/32—
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B08—CLEANING
- B08B—CLEANING IN GENERAL; PREVENTION OF FOULING IN GENERAL
- B08B13/00—Accessories or details of general applicability for machines or apparatus for cleaning
Abstract
The application discloses blood treatment facility and end cover cleaning device thereof, end cover cleaning device include end cover, first cleaning member and second cleaning member, and the end cover is used for setting up in the upside of casing and membrane bundle terminal surface, just the end cover can rotation on the casing, first cleaning member fixed set up in inside the end cover, first cleaning member is used for following during the end cover rotation the end cover rotates together, and the second cleaning member is used for fixed the upside that sets up in casing and membrane bundle terminal surface, so that the end cover drives when first cleaning member rotates first cleaning member promotes the thrombus extremely second cleaning member department. The end cover cleaning device can realize self cleaning of the end cover in the dialysis process.
Description
Technical Field
The application relates to the technical field of blood purification, in particular to an end cover cleaning device. It also relates to a blood treatment device.
Background
The biocompatibility mainly includes histocompatibility and hemocompatibility, and the quality of hemocompatibility directly affects the quality and service life of the dialyzer, so that a high-quality dialyzer is required to have not only excellent toxin-removing ability but also good hemocompatibility.
The dialyzer can form thrombus in the use, and most thrombus produces around the end cover, not only can influence dialysis patient's dialysis sufficiency, seriously can influence dialysis patient's quality of life. Mild thrombus formation can affect the toxin removing capacity of a dialyzer and reduce the dialysis sufficiency; the formation of severe thrombus forces the dialysis patient to get off, increasing the blood load of the patient, and possibly causing adverse symptoms such as hypotension. At present, the cleaning of a large amount of thrombus around the end cover needs to interrupt dialysis treatment, and the thrombus removal of the end cover cannot be realized in the dialysis process.
Therefore, how to provide an end cap cleaning device that solves the above technical problems is a technical problem that needs to be solved urgently by those skilled in the art.
Disclosure of Invention
The application aims at providing an end cover cleaning device, which can realize self-cleaning of an end cover in a dialysis process. It is another object of the present application to provide a blood treatment apparatus.
To achieve the above object, the present application provides an end cap cleaning device including:
the end cover is arranged on the upper side of the shell and the end face of the membrane bundle and can rotate on the shell;
the first cleaning piece is fixedly arranged in the end cover and used for rotating along with the end cover when the end cover rotates automatically;
and the second cleaning piece is fixedly arranged on the upper sides of the shell and the end face of the membrane bundle, so that when the end cover drives the first cleaning piece to rotate, the first cleaning piece pushes thrombus to the second cleaning piece.
Preferably, the first cleaning member is a cleaning brush, the second cleaning member is a baffle, and the first cleaning member and the second cleaning member are arranged on the end cover and the radius of the shell respectively.
Preferably, the cleaning brush is made of silica gel or polyurethane.
Preferably, the baffle is used for being integrated with the shell and made of the same material.
Preferably, the number of the cleaning brushes and the baffle plates is at least one and is distributed in axial symmetry.
Preferably, the handle member is disposed on the exterior of the end cap.
Preferably, the number of the handle pieces is one pair, and the handle pieces are arranged on two sides of the outer part of the end cover in a mirror image mode.
Preferably, the end cover further comprises a sealing element, wherein the sealing element is used for being arranged between the end cover and the shell to realize sealing when the end cover rotates.
Preferably, the end cap is provided with a groove in the interior thereof for mounting the seal.
The application also provides a blood treatment device, which adopts the end cover cleaning device.
Compared with the background art, the end cover cleaning device provided by the application is suitable for the existing blood treatment equipment, such as a hemodialyzer, a hemodiafiltration device, a hemofiltration device, a plasma separator and the like; the end covers on the upper sides of the shell and the membrane bundle end faces are provided with first cleaning pieces, and the upper sides of the shell and the membrane bundle end faces are provided with second cleaning pieces.
When the end cover cleaning device is used, the end cover is controlled to rotate on the shell, so that the first cleaning piece rotating along with the end cover pushes thrombus to the second cleaning piece, and the end cover thrombus is self-cleaned. This end cover cleaning device not only can realize the automatically cleaning of end cover thrombus, and the cleaning process can go on at the dialysis in-process moreover, consequently need not to interrupt the dialysis treatment, has avoided because of the forced machine of leaving and the blood loss that the thrombus formation leads to, ensures going on smoothly of blood treatment.
Drawings
In order to more clearly illustrate the embodiments of the present application or the technical solutions in the prior art, the drawings needed to be used in the description of the embodiments or the prior art will be briefly introduced below, it is obvious that the drawings in the following description are only embodiments of the present application, and for those skilled in the art, other drawings can be obtained according to the provided drawings without creative efforts.
FIG. 1 is an assembled schematic view of an end cap cleaning apparatus provided in an embodiment of the present application;
FIG. 2 is a bottom view of the tip cap of FIG. 1;
FIG. 3 is a top view of the housing of FIG. 1;
FIG. 4 is a flow chart of arterial pressure monitoring provided by an embodiment of the present application;
fig. 5 is a graph showing the variation of arterial pressure according to the embodiment of the present application.
Wherein:
1-end cover, 2-first cleaning piece, 3-blood channel, 4-handle piece, 5-groove, 6-second cleaning piece, 7-sealing piece, 8-membrane bundle end face and 9-shell.
Detailed Description
The technical solutions in the embodiments of the present application will be clearly and completely described below with reference to the drawings in the embodiments of the present application, and it is obvious that the described embodiments are only a part of the embodiments of the present application, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present application.
In order to better understand the technical scheme of the present application, the following detailed description is provided for the person skilled in the art with reference to the accompanying drawings and the detailed description.
Referring to fig. 1 to fig. 3, fig. 1 is an assembly schematic diagram of an end cap cleaning device according to an embodiment of the present application, fig. 2 is a bottom view of an end cap in fig. 1, and fig. 3 is a top view of a housing in fig. 1.
In a first particular embodiment, the present application provides an end cap cleaning device comprising an end cap 1, a first cleaning member 2 and a second cleaning member 6.
The end cap 1 is arranged above a shell 9 and a membrane bundle end face 8 of the blood treatment equipment, and the end cap 1 can rotate on the shell 9. The first cleaning piece 2 is fixedly arranged in the end cover 1 and rotates together with the end cover 1 when the end cover 1 rotates. The second cleaning member 6 is fixedly arranged on the upper side of the shell 9 and the membrane bundle end face 8.
The end cap cleaning device is suitable for the existing blood processing equipment, and is equivalent to improving the cover body structure of the existing blood processing equipment, so that the cover body structure of the blood processing equipment has the self-cleaning function of the end cap 1 in the application; the blood treatment device may be a hemodialyzer, a hemodiafiltration device, a hemofiltration device, a plasma separator, etc., and shall fall within the scope of the present embodiment.
In this embodiment, the cleaning elements are the first cleaning element 2 and the second cleaning element 6, the first cleaning element 2 being the moving element and the second cleaning element 6 being the stationary element. The thrombi are swept by the first cleaning members 2 and moved to the second cleaning members 6 by the sweeping of the first cleaning members 2.
Specifically, during the use of the end cover cleaning device, the end cover 1 is controlled to rotate on the shell 9, so that the first cleaning pieces 2 rotating together with the end cover 1 push thrombus to the second cleaning pieces 6, and the thrombus in the end cover 1 is self-cleaned.
This end cover cleaning device not only can realize the automatically cleaning of thrombus in the end cover 1, and the cleaning process can go on at the dialysis in-process moreover, consequently need not to interrupt the dialysis treatment, has avoided because of the thrombus formation leads to being forced machine and blood loss down, ensures going on smoothly of blood treatment.
In some embodiments, the first cleaning members 2 are cleaning brushes, the second cleaning members 6 are baffles, and the first cleaning members 2 and the second cleaning members 6 are configured to be disposed on a radius of the end cap 1 and the housing 9, respectively.
In this embodiment, the length of the cleaning brush may be shorter than the inner radius of the end cap 1, and when the cleaning brush is rotated to clean, the cleaning brush disposed on the radius of the end cap 1 surrounds 360 degrees around the entire circumference to clean thrombus in the end cap 1 to the baffle side.
Illustratively, the cleaning brush is made of silica gel or polyurethane.
Illustratively, the baffle is formed integrally with and of the same material as the housing 9.
In some embodiments, the number of the cleaning brushes and the baffle plates is at least one and is distributed in axial symmetry.
In this embodiment, the number of the cleaning brushes and the baffles may be 1-2, which is within the scope of the present embodiment.
Taking the number of the cleaning brushes and the baffles as 1 as an example: during dialysis treatment, the baffle is fixed, and the cleaning brush is abutted against the first side of the baffle; the end covers 1 at the two ends of the dialyzer are rotated forwards for 360 degrees, and the thrombus is cleaned to the second side of the baffle plate by the cleaning brush; on the basis, the cleaning brush can also be rotated in a reverse direction for one circle, and the scope of the present embodiment should be covered.
Exemplarily, the dialysis starts with 1 rotation at 0 h; 1h, 2h, 3h, 4h rotate end cover 1 two circles constantly, guarantee that the thrombus cleans the second side of baffle, and rotatory back cleaning brush and baffle play the effect of fixed thrombus.
In some embodiments, a handle member 4 is also included, the handle member 4 being disposed on the exterior of the end cap 1.
In this embodiment, the handle member 4 is a rotary handle for ease of manipulation; when the rotation of the end cap 1 needs to be controlled, the rotation control of the end cap 1 is easier to realize by controlling the handle piece 4.
Illustratively, the number of the handle members 4 is a pair, and the handle members 4 are arranged on two sides of the outer part of the end cover 1 in a mirror image mode.
Besides, the end cover comprises a sealing member 7, and the sealing member 7 is used for being arranged between the end cover 1 and the shell 9 to realize sealing when the end cover 1 rotates.
In this embodiment, the sealing member 7 may be an O-ring, which functions to connect the end cap 1 and the housing 9 and to freely rotate the end cap 1 relatively.
Illustratively, the interior of the end cap 1 is provided with a groove 5 for mounting a seal 7.
In this embodiment, the upper side of the O-ring is fitted in the groove 5 of the end cap 1, and the lower side of the O-ring is in close contact with the upper edge of the housing 9, thereby performing a sealing function.
In addition, a blood channel 3 is arranged at the central position of the end cap 1, and the blood channel 3 is used for realizing the inlet and outlet of blood. It should be noted that the length of the cleaning brush and the baffle plate is designed to be smaller than the radius of the inside of the end cap 1, so that the end cap 1 can avoid the blood channel 3 when rotating, and the use of the blood treatment equipment is not affected.
Illustratively, in the illustrated dimensions, L1=25mm, L2=23mm, L3=8mm, L4=13mm, L5=6mm, and L6=2mm.
Referring to fig. 4, fig. 4 is a flowchart of arterial pressure monitoring provided in an embodiment of the present application.
In the arterial pressure monitoring shown in fig. 4: in the dialysis treatment process, a dialysis machine is adopted to monitor the arterial pressure in real time, if the arterial pressure alarms at any time, the operation of rotating the end cover 1 to clean thrombus needs to be immediately carried out, and then the machine alarms and resets. If the alarm can not be reset, after the blood coagulation reason of the venous pot is eliminated, the operation of cleaning the thrombus by rotating the end cover 1 is repeated until the alarm is relieved; if no alarm is given to arterial pressure in the dialysis process, the operation of cleaning thrombus by rotating the end cover 1 can be carried out when dialysis is carried out for 0.5h, 1h, 2h, 3h and 4 h.
In a performance characterization of the end cap cleaning device:
clinical dialysis was simulated. Taking 1 dialyzer, respectively adopting 200mL fresh pig blood for simulating clinical dialysis, adopting 3.8% sodium citrate for anticoagulation, wherein the volume ratio of the anticoagulant to the blood is (1. In the same way, 1 dialyzer with the same specification is prepared by using the same blood without rotating the handle member 4.
TABLE 1 test parameters
| Simulated dialysis time/h | 0 | 0.5 | 1 | 2 | 3 | 4 |
| Anterior clean arterial pressure/mmHg | 84 | 104 | 117 | 126 | 132 | 137 |
| Arterial pressure/mmHg after cleaning | 82 | 95 | 101 | 111 | 114 | 123 |
| Unclean arterial pressure/mmHg | 81 | 107 | 124 | 139 | 151 | 187 |
And (5) drawing a time t-arterial pressure p change curve. Referring to fig. 5, fig. 5 is a graph showing the variation of arterial pressure according to the embodiment of the present application.
This application still provides a blood treatment facility, adopts above-mentioned end cover cleaning device, has improved in the lid structure to current blood treatment facility in other words, should have above-mentioned end cover cleaning device's whole beneficial effect, and here no longer gives unnecessary details.
In this embodiment, the blood treatment device may be a hemodialyzer, hemodiafiltration device, hemofiltration device, plasma separator, etc., and shall also fall within the scope of the description of this embodiment.
Taking the dialyzer as an example, the dissection analysis of the dialyzer after thrombus formation shows that most of thrombus is generated around the end cap 1, and the internal structure of the hollow fiber is completely preserved. This is because the blood flow rate is fast at the center of the end cap 1, and thrombus is not easily formed; on the contrary, the blood flow rate near the edge of the end cap 1 is relatively slow, so that a 'dead space' is generated sometimes, so that thrombus is easily formed around the end cap 1 in the dialysis process, and the end cap 1 aims to remove the thrombus in the end cap 1 by rotating the end cap 1, so that the occurrence of the dialysis interruption phenomenon is avoided, and the clinical operation value is realized.
It should be noted that many of the components mentioned in this application are either common standard components or components known to those skilled in the art, and their structure and principle are known to those skilled in the art through technical manuals or through routine experimentation.
It is noted that, in this specification, relational terms such as first and second, and the like are used solely to distinguish one entity from another entity without necessarily requiring or implying any actual such relationship or order between such entities.
The blood processing apparatus and the end cap cleaning device thereof provided by the present application are described in detail above. The principles and embodiments of the present application are described herein using specific examples, which are only used to help understand the method and its core idea of the present application. It should be noted that, for those skilled in the art, it is possible to make several improvements and modifications to the present application without departing from the principle of the present application, and such improvements and modifications also fall within the scope of the claims of the present application.
Claims (9)
1. An end cap cleaning device, comprising:
the end cover (1) is arranged on the upper side of a shell (9) and a membrane bundle end face (8) of the blood treatment equipment, and the end cover (1) can rotate on the shell (9);
the first cleaning piece (2), in particular a cleaning brush, is fixedly arranged in the end cover (1) and is positioned on the radius of the end cover (1) and used for rotating together with the end cover (1) when the end cover (1) rotates;
the second cleaning piece (6), in particular to a baffle plate, is fixedly arranged on the upper side of the shell (9) and the membrane bundle end face (8) and is positioned on the radius of the shell (9), so that when the end cover (1) drives the first cleaning piece (2) to rotate, the first cleaning piece (2) pushes thrombus to the second cleaning piece (6);
during the use process, the end cover (1) is controlled to rotate on the shell (9), so that the first cleaning piece (2) rotating together with the end cover (1) pushes thrombus to the second cleaning piece (6), and the thrombus at the end cover (1) is self-cleaned; the use can be performed during dialysis.
2. An end cap cleaning device according to claim 1, wherein the cleaning brush is made of silicone or polyurethane.
3. An end cap cleaning device according to claim 1, wherein the baffle is adapted to be integral with and of the same material as the housing (9).
4. The end cap cleaning apparatus of claim 1, wherein the cleaning brush and the baffle are each at least one in number.
5. The end cap cleaning device according to any one of claims 1 to 4, further comprising a handle member (4), the handle member (4) being disposed outside the end cap (1).
6. The end cap cleaning device according to claim 5, characterized in that the number of the handle members (4) is one pair, and a pair of the handle members (4) are arranged on two sides of the outer part of the end cap (1) in a mirror image mode.
7. An end cap cleaning device according to any one of claims 1 to 4, further comprising a sealing member (7), wherein the sealing member (7) is arranged between the end cap (1) and the housing (9) to realize sealing when the end cap (1) rotates.
8. An end cap cleaning device according to claim 7, wherein the inside of the end cap (1) is provided with a groove (5) for mounting the sealing member (7).
9. A blood processing apparatus, wherein the tip cap cleaning device according to any one of claims 1 to 8 is used.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202210319283.0A CN114669520B (en) | 2022-03-29 | 2022-03-29 | Blood treatment facility and end cover cleaning device thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202210319283.0A CN114669520B (en) | 2022-03-29 | 2022-03-29 | Blood treatment facility and end cover cleaning device thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN114669520A CN114669520A (en) | 2022-06-28 |
| CN114669520B true CN114669520B (en) | 2023-03-24 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN202210319283.0A Active CN114669520B (en) | 2022-03-29 | 2022-03-29 | Blood treatment facility and end cover cleaning device thereof |
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Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2003047777A2 (en) * | 2001-12-06 | 2003-06-12 | Barrie Mellor | Cleaning process and apparatus |
| CN111826267A (en) * | 2020-07-07 | 2020-10-27 | 湖北明德健康科技有限公司 | Stem cell collection device |
| CN113231413A (en) * | 2021-06-24 | 2021-08-10 | 吉林大学中日联谊医院 | Hemodialysis pipe cleaning and sterilizing device |
| CN214549196U (en) * | 2021-01-18 | 2021-11-02 | 曾懿苇 | Portable high-efficient blood stain clearing device |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8247191B2 (en) * | 2008-11-13 | 2012-08-21 | Ritzen Kalle | Disposable cassette and method of use for blood analysis on blood analyzer |
| ES2577288B8 (en) * | 2015-01-13 | 2019-01-10 | Anaconda Biomed S L | Device for thrombectomy |
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2022
- 2022-03-29 CN CN202210319283.0A patent/CN114669520B/en active Active
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2003047777A2 (en) * | 2001-12-06 | 2003-06-12 | Barrie Mellor | Cleaning process and apparatus |
| CN111826267A (en) * | 2020-07-07 | 2020-10-27 | 湖北明德健康科技有限公司 | Stem cell collection device |
| CN214549196U (en) * | 2021-01-18 | 2021-11-02 | 曾懿苇 | Portable high-efficient blood stain clearing device |
| CN113231413A (en) * | 2021-06-24 | 2021-08-10 | 吉林大学中日联谊医院 | Hemodialysis pipe cleaning and sterilizing device |
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| CN114669520A (en) | 2022-06-28 |
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