CN114601558A - Laser ablation catheter with variable optical fiber spiral angle - Google Patents

Laser ablation catheter with variable optical fiber spiral angle Download PDF

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Publication number
CN114601558A
CN114601558A CN202210344573.0A CN202210344573A CN114601558A CN 114601558 A CN114601558 A CN 114601558A CN 202210344573 A CN202210344573 A CN 202210344573A CN 114601558 A CN114601558 A CN 114601558A
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China
Prior art keywords
ablation catheter
laser ablation
optical fiber
layer
inner lining
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Pending
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CN202210344573.0A
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Chinese (zh)
Inventor
吴寒
苏蕾
马修泉
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Huazhong University of Science and Technology
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Huazhong University of Science and Technology
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Priority to CN202210344573.0A priority Critical patent/CN114601558A/en
Publication of CN114601558A publication Critical patent/CN114601558A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/18Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves
    • A61B18/20Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser
    • A61B18/22Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser the beam being directed along or through a flexible conduit, e.g. an optical fibre; Couplings or hand-pieces therefor
    • A61B18/24Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser the beam being directed along or through a flexible conduit, e.g. an optical fibre; Couplings or hand-pieces therefor with a catheter
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00315Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for treatment of particular body parts
    • A61B2018/00345Vascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00571Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for achieving a particular surgical effect
    • A61B2018/00577Ablation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/18Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves
    • A61B18/20Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser
    • A61B18/22Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser the beam being directed along or through a flexible conduit, e.g. an optical fibre; Couplings or hand-pieces therefor
    • A61B2018/2205Characteristics of fibres
    • A61B2018/2211Plurality of fibres
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/18Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves
    • A61B18/20Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser
    • A61B18/22Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser the beam being directed along or through a flexible conduit, e.g. an optical fibre; Couplings or hand-pieces therefor
    • A61B2018/2244Features of optical fibre cables, e.g. claddings

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  • Health & Medical Sciences (AREA)
  • Surgery (AREA)
  • Physics & Mathematics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medical Informatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Electromagnetism (AREA)
  • Optics & Photonics (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Otolaryngology (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Laser Surgery Devices (AREA)
  • Media Introduction/Drainage Providing Device (AREA)

Abstract

The invention discloses a laser ablation catheter with variable optical fiber spiral angle, belonging to the technical field related to medical instruments, and comprising an outer cladding layer, an inner lining layer and an optical fiber; the outer cladding layer and the inner lining layer are coaxially arranged in parallel, and a plurality of layers of optical fibers are arranged between the outer cladding layer and the inner lining layer; the optical fiber is distributed and changed from being parallel to the inner lining layer to being spirally distributed around the inner lining layer from the laser input end of the laser ablation catheter to the laser output end of the laser ablation catheter. The invention achieves the purpose of enabling the laser ablation catheter to have better mechanical properties at different positions in the blood vessel through the structural design of the optical fiber, improves the flexibility of the laser ablation catheter, ensures the operability of the catheter, reduces the body damage to a patient, and is suitable for medical scenes such as quasi-molecule laser coronary plaque ablation operation and the like.

Description

Laser ablation catheter with variable optical fiber spiral angle
Technical Field
The invention belongs to the technical field related to medical instruments, and particularly relates to a laser ablation catheter with variable optical fiber spiral angles.
Background
The ELCA operation mainly transmits ultraviolet light pulses to a hardened part through a laser catheter, the action mechanism is photochemical, photothermal and optomechanical actions between laser and tissues, and the hardened plaque can be ablated by direct action between the laser and the tissues or rapid expansion and collapse of generated water vapor, so that the purpose of eliminating the hardened plaque is achieved. Laser catheters are catheters designed to deliver laser light to a lesion in an artery that contain optical fibers that must be made of very pure fused silica (synthetic quartz), and ordinary glass fibers are no longer capable of transmitting ultraviolet light at the power levels necessary for surgery.
The common quartz optical fiber catheter used in the current operation has poor advancing effect in a bent blood vessel, can cause certain damage to the blood vessel of a patient, generates postoperative complications and is inconvenient for a doctor to operate.
Thus, there is a great need in the market place
Disclosure of Invention
In view of the above drawbacks or needs for improvement in the prior art, the present invention provides a fiber-varied spiral angle laser ablation catheter, which aims to change the arrangement structure of optical fibers from the laser input end of the fiber-varied spiral angle laser ablation catheter to the laser output end of the fiber-varied spiral angle laser ablation catheter, thereby solving the technical problem of poor advancing effect of the conventional fiber-varied spiral angle laser ablation catheter in a curved blood vessel.
To achieve the above objects, according to one aspect of the present invention, there is provided a laser ablation catheter with variable fiber helix angle, the laser ablation catheter comprising an outer covering, an inner covering, and an optical fiber;
the outer cladding layer and the inner lining layer are coaxially arranged in parallel, and a plurality of layers of optical fibers are arranged between the outer cladding layer and the inner lining layer;
the optical fiber is from the laser input end of the laser ablation catheter to the laser output end of the laser ablation catheter and is distributed and changed from being parallel to the inner lining layer to being spirally distributed around the inner lining layer.
Preferably, the optical fiber is provided with two layers, and the two layers of optical fibers are coaxially arranged.
Preferably, an epoxy resin bonding layer is further arranged between the outer cladding layer and the inner lining layer and used for filling and bonding a gap between the optical fibers, so that the outer cladding layer, the inner lining layer and the optical fibers form an integral structure.
Preferably, the outer cladding is made of polytetrafluoroethylene material, and the outer surface of the outer cladding is coated with a lubricating material.
Preferably, the inner liner is made of polytetrafluoroethylene material, and the inner surface of the inner liner is coated with a lubricating material.
Preferably, the laser ablation catheter is further provided with a positioning ring, and the positioning ring is arranged on the end face of the laser output end of the laser ablation catheter and used for displaying the position of the laser ablation catheter in the blood vessel.
Preferably, the positioning ring is made of an X-ray opaque material, and a hydrophobic coating is arranged on the outer layer of the positioning ring.
Preferably, the laser ablation catheter further comprises a metal guide wire, wherein the metal guide wire penetrates through the inner liner layer and is used for drawing the laser ablation catheter to move.
Preferably, the metal guide wire is made of a metal material without biological toxicity and biological activity.
Preferably, the diameter of the metal guide wire is 0.008inch to 0.016 inch.
In general, compared with the prior art, the above technical solution contemplated by the present invention can achieve the following beneficial effects:
1. according to the laser ablation catheter with the variable optical fiber spiral angle, the optical fiber is changed from being distributed in parallel with the inner liner layer to being distributed spirally around the inner liner layer from the laser input end of the laser ablation catheter to the laser output end of the laser ablation catheter, so that the far end of the laser ablation catheter has good flexibility, is easy to bend after entering a blood vessel, can reach a focus part more smoothly, and reduces the harm to a patient in the operation process; the near end of the laser ablation catheter has better operability and is not easy to bend, so that the catheter can be better pushed along the trunk aorta, and a doctor can conveniently control the catheter.
2. The laser ablation catheter with the variable optical fiber spiral angle is convenient to operate and good in compatibility with the original device by designing the arrangement mode of the optical fibers, facilitates the improvement of the existing device, improves the operation effect of the vascular ablation operation, and reduces the postoperative risk.
Drawings
Fig. 1 is a schematic structural view of a fiber helix angle variable laser ablation catheter of the present invention.
The same reference numbers will be used throughout the drawings to refer to the same or like elements or structures, wherein: 1-an outer cladding; 2-an epoxy resin adhesive layer; 3-an optical fiber; 3.1-optical fiber spiral section; 3.2-parallel section of optical fiber; 4-an inner liner layer; 5-a metal guide wire; 6-positioning ring.
Detailed Description
In order to make the objects, technical solutions and advantages of the present invention more apparent, the present invention is described in further detail below with reference to the accompanying drawings and embodiments. It should be understood that the specific embodiments described herein are merely illustrative of the invention and are not intended to limit the invention. In addition, the technical features involved in the embodiments of the present invention described below may be combined with each other as long as they do not conflict with each other.
The invention provides a laser ablation catheter with a variable optical fiber spiral angle, which achieves the purpose of enabling the laser ablation catheter to have better mechanical properties at different positions in a blood vessel through the structural design of optical fibers, improves the flexibility of the laser ablation catheter, ensures the operability of the catheter, reduces the body damage to a patient, and is suitable for medical scenes such as quasi-molecular laser coronary plaque ablation operation and the like.
Specifically, as shown in fig. 1, the laser ablation catheter with the variable optical fiber spiral angle comprises an outer cladding layer 1, an optical fiber 3, an inner lining layer 4, a metal guide wire 5 and a positioning ring 6.
Metal seal wire 5 run through in the intracavity of inner liner 4, surrounding layer 1 with inner liner 4 is the cylinder, and the two is parallel with the axle center, the 1 outside of surrounding layer with 4 inboard of inner liner scribble the lubricating coating, 1 distal end of surrounding layer is equipped with holding ring 6, surrounding layer 1 with wrap up between the inner liner 4 optical fiber 3 for transmit laser.
More specifically, the metal guide wire 5 is made of food-grade stainless steel. In a preferred embodiment of the present invention, the diameter of the metal guide wire 5 is 0.008inch to 0.014 inch.
Further, the outer cladding layer 1 and the inner lining layer 4 are made of polytetrafluoroethylene materials which are free of toxic, sensitizing and carcinogenic side effects, and hydrophobic materials such as polyvinylpyrrolidone are adopted for the surface lubricating coating.
In a further description, the lining layer 4 provides a moving channel for the metal guide wire 5, and the metal guide wire and the lining layer are in a tolerance-free fit relationship.
In further detail, the diameter and the length of the laser ablation catheter are set to different sizes, the diameter is 1.4mm at the minimum and 2.6mm at the maximum, the total length of the catheter is 130cm to 160cm, and different models are selected according to the physical condition of a patient.
In further detail, the optical fiber 3 is provided with an optical fiber spiral section 3.1 with a pitch of 5cm at a position of 30cm from the far end of the laser catheter, and the rest part is an optical fiber parallel section 3.2; the optical fiber is arranged in two layers in parallel and coaxially, and the optical fiber 3 is bonded with the outer cladding layer 1 and the inner lining layer 4 by epoxy resin.
More specifically, the positioning ring 6 is mounted on the distal end face of the laser ablation catheter and is made of an X-ray opaque material such as lead, and the outer layer of the positioning ring is coated with a hydrophobic coating.
Through the structural design of the catheter, the purpose that the laser ablation catheter has better mechanical properties at different positions in a blood vessel is achieved, the flexibility of the laser catheter is improved, the operability of the catheter is ensured, the body damage to a patient is reduced, and the catheter is suitable for medical scenes such as excimer laser coronary plaque ablation operations.
In the embodiment of the invention, the laser ablation catheter is a working part entering the aorta of a human body, the external part of the body is connected with a metal guide wire access port, a catheter extension part and a coupler, the coupler is inserted into an excimer laser, and laser generated by the laser is transmitted to a focus position along the catheter through an optical fiber. An orientation handle and a grip and other parts can be arranged at the proximal end of the working part of the catheter for the convenience of the doctor. The additional parts are all existing products and are not described in detail.
When the quasi-molecule laser coronary plaque ablation is implemented, firstly, a metal guide wire is introduced into an aorta through a puncture sheath, then, a laser ablation catheter is introduced, the laser ablation catheter is moved along with the metal guide wire, the position of the laser ablation catheter can be seen through an angiography positioning technology, after the position reaches a coronary artery occlusion focus, a laser starts to work, and generated pulse laser ablates the plaque, so that the treatment purpose is achieved.
It will be understood by those skilled in the art that the foregoing is only a preferred embodiment of the present invention, and is not intended to limit the invention, and that any modification, equivalent replacement, or improvement made within the spirit and principle of the present invention should be included in the scope of the present invention.

Claims (10)

1. The laser ablation catheter with the variable optical fiber spiral angle is characterized by comprising an outer cladding layer (1), an inner lining layer (4) and an optical fiber (3);
the outer cladding layer (1) and the inner lining layer (4) are coaxially arranged in parallel, and a plurality of layers of optical fibers (3) are arranged between the outer cladding layer (1) and the inner lining layer (4);
the optical fiber (3) is from the laser input end of the laser ablation catheter to the laser output end of the laser ablation catheter and is distributed and changed from being parallel to the inner lining layer (4) to being spirally distributed around the inner lining layer (4).
2. A variable fiber helix angle laser ablation catheter as claimed in claim 1, wherein the optical fiber (3) has two layers, and the two layers of optical fiber (3) are coaxially arranged.
3. The laser ablation catheter with the variable optical fiber helix angle as claimed in claim 2, wherein an epoxy resin bonding layer (2) is further disposed between the outer cladding layer (1) and the inner lining layer (4), and the epoxy resin bonding layer (2) is used for filling and bonding the gaps between the optical fibers (3), so that the outer cladding layer (1), the inner lining layer (4) and the optical fibers (3) form an integral structure.
4. A microfiber spiral angle laser ablation catheter according to claim 1, wherein the outer covering layer (1) is made of teflon material, and its outer surface is coated with lubricant material.
5. A variable fiber helix angle laser ablation catheter as claimed in claim 1, wherein the inner liner (4) is made of teflon material, and the inner surface thereof is coated with a lubricating material.
6. The variable optical fiber spiral angle laser ablation catheter as claimed in claim 1, wherein the laser ablation catheter is further provided with a positioning ring (6), and the positioning ring (6) is arranged at the laser output end face of the laser ablation catheter and is used for displaying the position of the laser ablation catheter in a blood vessel.
7. A variable fiber helix angle laser ablation catheter according to claim 6, characterized in that the positioning ring (6) is made of X-ray opaque material and has a hydrophobic coating on its outer layer.
8. A variable optical fiber helix angle laser ablation catheter according to claim 1, characterized by further comprising a metal guide wire (5), wherein the metal guide wire (5) is arranged through the inner liner layer (4) for drawing the laser ablation catheter to move.
9. A variable fiber helix angle laser ablation catheter as claimed in claim 8, wherein the metal guide wire (5) is made of a non-biotoxic and bioactive metal material.
10. The laser ablation catheter with the variable optical fiber helix angle is characterized in that the diameter of the metal guide wire (5) is 0.008inch to 0.016 inch.
CN202210344573.0A 2022-03-31 2022-03-31 Laser ablation catheter with variable optical fiber spiral angle Pending CN114601558A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115032738A (en) * 2022-06-27 2022-09-09 上海昊量光电设备有限公司 Hollow optical fiber bundle, optical fiber bundle laser device and processing and manufacturing method thereof
CN116025867A (en) * 2023-01-03 2023-04-28 南京春辉科技实业有限公司 Optical fiber illumination light guide rod

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5415653A (en) * 1992-08-26 1995-05-16 Advanced Interventional Systems, Inc. Optical catheter with stranded fibers
US20180344528A1 (en) * 2017-05-30 2018-12-06 Novartis Ag Multi-fiber multi-spot laser probe with articulating beam separation
CN112998851A (en) * 2021-02-26 2021-06-22 华中科技大学 High-flexibility low-loss ablation laser catheter for coronary heart disease treatment

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5415653A (en) * 1992-08-26 1995-05-16 Advanced Interventional Systems, Inc. Optical catheter with stranded fibers
US20180344528A1 (en) * 2017-05-30 2018-12-06 Novartis Ag Multi-fiber multi-spot laser probe with articulating beam separation
CN112998851A (en) * 2021-02-26 2021-06-22 华中科技大学 High-flexibility low-loss ablation laser catheter for coronary heart disease treatment

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115032738A (en) * 2022-06-27 2022-09-09 上海昊量光电设备有限公司 Hollow optical fiber bundle, optical fiber bundle laser device and processing and manufacturing method thereof
CN115032738B (en) * 2022-06-27 2023-10-20 上海昊量光电设备有限公司 Hollow optical fiber bundle, optical fiber bundle laser device and processing and manufacturing method thereof
CN116025867A (en) * 2023-01-03 2023-04-28 南京春辉科技实业有限公司 Optical fiber illumination light guide rod
CN116025867B (en) * 2023-01-03 2023-09-29 南京春辉科技实业有限公司 Optical fiber illumination light guide rod

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