CN114216872A - Glycosylated hemoglobin analyzer - Google Patents
Glycosylated hemoglobin analyzer Download PDFInfo
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- CN114216872A CN114216872A CN202111545136.7A CN202111545136A CN114216872A CN 114216872 A CN114216872 A CN 114216872A CN 202111545136 A CN202111545136 A CN 202111545136A CN 114216872 A CN114216872 A CN 114216872A
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
- G01N21/31—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/01—Arrangements or apparatus for facilitating the optical investigation
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/01—Arrangements or apparatus for facilitating the optical investigation
- G01N2021/0106—General arrangement of respective parts
- G01N2021/0112—Apparatus in one mechanical, optical or electronic block
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/1717—Systems in which incident light is modified in accordance with the properties of the material investigated with a modulation of one or more physical properties of the sample during the optical investigation, e.g. electro-reflectance
- G01N2021/1731—Temperature modulation
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- Investigating Or Analysing Materials By Optical Means (AREA)
Abstract
The invention discloses a glycosylated hemoglobin analyzer, comprising: a mounting frame; the chromatography mechanism is arranged on the mounting frame; the detection mechanism is arranged on the mounting frame and is connected with the chromatography mechanism through a pipeline; and the temperature control mechanism is arranged on the mounting frame and used for keeping the temperature of the inner cavity of the detection mechanism constant. The glycosylated hemoglobin analyzer is provided with only one detection mechanism, so that the structure is simpler, the cost is lower, and the control system is simpler and the installation and debugging are simpler due to the adoption of one detection mechanism.
Description
Technical Field
The invention relates to the technical field of biological detection devices, in particular to a glycosylated hemoglobin analyzer.
Background
At present, the detection of the glycosylated hemoglobin is generally carried out by combining an ion exchange High Performance Liquid Chromatography (HPLC) and a dual-wavelength (main wavelength: 415 nm; secondary wavelength: 500nm) visible light colorimetric method in modern medical clinical laboratories.
According to lambert-Beer's law, the absorbance of a solution is equal to the product of the absorption coefficient, the concentration C and the optical path l (cm) of the solution, i.e., a ═ epsilon CL; when the optical path is unchanged, the concentration is in direct proportion to the absorbance, so that the concentration of each component in the hemoglobin can be obtained by testing the absorbance, and the percentage of the glycated hemoglobin in the total hemoglobin is calculated. The absorbance A is defined as the degree of light absorption of the solution, and is respectively shown in the following formula and the lower graph;
in the above formula, It is the intensity of emergent light, Io is the intensity of incident light, where It is related to the sample, the hemoglobin concentration of the test sample is different, and the test result of It is also different; io is related to the intensity of the light source, and the result of Io is stable in most cases unless abnormal conditions such as temperature drift occur, and for this reason, in instruments for glycated hemoglobin, Io is generally not detected by a special detector. Under this condition, in order to stop the influence that temperature drift brought, generally speaking, can adopt the dual wavelength method to test, adopts the detection device of dual wavelength visible light colorimetric method, needs to set up two way signal receiving element at the detection end usually structurally, gathers optical detection signal all the way, gathers reference signal all the way, obtains the parameter of absorbance after comparing, handling these two optical signal values at last. Although the dual-wavelength structure can reduce the influence of interference factors such as temperature drift on the test result, the detection device with the structure has the defects of complex structure, difficult installation and debugging, complex control system, high cost and the like.
Accordingly, the prior art is yet to be improved and developed.
Disclosure of Invention
The invention aims to solve the technical problems that the glycosylated hemoglobin analyzer is provided aiming at the defects of the prior art, and the problems that the glycosylated hemoglobin analyzer in the prior art has two sets of detection systems, so that the device is complex in structure, higher in cost, complex in control system and more difficult to install and debug are solved.
In order to solve the technical problems, the technical scheme adopted by the invention is as follows:
a glycated hemoglobin analyzer, the glycated hemoglobin analyzer comprising:
a mounting frame;
the chromatography mechanism is arranged on the mounting frame;
the detection mechanism is arranged on the mounting frame and is connected with the chromatography mechanism through a pipeline; and
the temperature control mechanism is arranged on the mounting frame and used for keeping the temperature of the inner cavity of the detection mechanism constant.
The glycated hemoglobin analyzer, wherein the temperature control mechanism comprises:
the optical large bottom plate is arranged on the mounting frame and is positioned at the bottom of the detection mechanism;
the optical heating sheet is arranged on the mounting frame, is positioned on one side, back to the detection mechanism, of the optical large bottom plate, and is used for heating the optical large bottom plate;
the control mechanism is electrically connected with the optical heating sheet; and
the temperature sensor is positioned on the optical large bottom plate and is electrically connected with the control mechanism.
The glycated hemoglobin analyzer, wherein the control mechanism comprises:
the upper mounting cover is connected with the optical large bottom plate;
the lower mounting cover is connected with the upper mounting cover, and a first accommodating cavity is formed between the lower mounting cover and the upper mounting cover; and
the optical plate is clamped in the first accommodating cavity, and the optical plate is respectively electrically connected with the temperature sensor and the optical heating sheet.
The glycosylated hemoglobin analyzer is characterized in that a plurality of first heightening columns are arranged between the optical large bottom plate and the control mechanism, and the control mechanism is electrically connected with the optical heating sheet through the plurality of first heightening columns.
The glycosylated hemoglobin analyzer is characterized in that the control mechanism is located on one side, back to the optical large bottom plate, of the optical heating sheet, a plurality of abdicating grooves are formed in the optical heating sheet and correspond to the first heightening columns one by one, and the first heightening columns penetrate through the corresponding abdicating grooves.
The glycosylated hemoglobin analyzer is characterized in that a temperature switch is further arranged on the mounting rack, extends from one side of the mounting rack to be embedded into the optical large bottom plate and is electrically connected with the optical large bottom plate.
The glycated hemoglobin analyzer, wherein the detection mechanism includes:
the outer cover is arranged on the mounting frame, and a second accommodating cavity is formed in the outer cover;
the light source detection assembly is arranged on the temperature control mechanism and located in the second accommodating cavity, and the light source detection assembly is connected with the chromatography mechanism through a pipeline.
The glycosylated hemoglobin analyzer is characterized in that the temperature control mechanism is provided with a plurality of fixing assemblies, the fixing assemblies are all arranged in the second accommodating cavity, the uniform end of each fixing assembly is connected with the temperature control mechanism, and the other end of each fixing assembly is connected with the top of the outer cover.
The glycated hemoglobin analyzer, wherein the fixing member comprises:
one end of the vertical rod support is connected with the temperature control mechanism;
and one end of the second heightening column is connected with the vertical rod support, and the other end of the second heightening column is connected with the top of the outer cover.
The glycated hemoglobin analyzer, wherein the chromatography mechanism includes:
the mounting seat is arranged on the mounting frame;
the chromatographic column is arranged in the inner cavity of the mounting seat and is connected with the pipeline of the detection mechanism.
Has the advantages that: the glycosylated hemoglobin analyzer is provided with only one detection mechanism, so that the structure is simpler, the cost is lower, and the control system is simpler and the installation and debugging are simpler due to the adoption of one detection mechanism.
Drawings
FIG. 1 is a schematic view showing the structure of the glycated hemoglobin analyzer according to the present invention;
FIG. 2 is a schematic exploded view of the glycated hemoglobin analyzer according to the present invention;
the labels in the figures are: 1. a mounting frame; 2. a chromatography mechanism; 21. a mounting seat; 22. a chromatography column; 3. a detection mechanism; 31. a housing; 32. a light source detection assembly; 4. a temperature control mechanism; 41. an optical backplane; 42. an optical heating sheet; 43. a control mechanism; 431. an upper mounting cover; 432. a lower mounting cover; 433. an optical board card; 44. a temperature sensor; 5. a first heightening column; 6. a yielding groove; 7. a temperature switch; 8. a supporting seat; 9. a fixing assembly; 91. a vertical rod support; 92. a second elevated column.
Detailed Description
The present invention provides a glycated hemoglobin analyzer, which will be described in further detail below with reference to the accompanying drawings and examples in order to make the objects, technical solutions, and effects of the present invention clearer and clearer. It should be understood that the specific embodiments described herein are merely illustrative of the invention and are not intended to limit the invention.
It will be understood that when an element is referred to as being "secured to" or "disposed on" another element, it can be directly on the other element or be indirectly on the other element. When an element is referred to as being "connected to" another element, it can be directly connected to the other element or be indirectly connected to the other element.
It should also be noted that the same or similar reference numerals in the drawings of the embodiments of the present invention correspond to the same or similar components; in the description of the present invention, it should be understood that if there is an orientation or positional relationship indicated by the terms "upper", "lower", "left", "right", etc. based on the orientation or positional relationship shown in the drawings, it is only for convenience of describing the present invention and simplifying the description, but it is not intended to indicate or imply that the referred device or element must have a specific orientation, be constructed in a specific orientation, and be operated, and therefore, the terms describing the positional relationship in the drawings are only used for illustrative purposes and are not to be construed as limiting the present patent, and the specific meaning of the terms may be understood by those skilled in the art according to specific circumstances.
Furthermore, the terms "first", "second" and "first" are used for descriptive purposes only and are not to be construed as indicating or implying relative importance or implicitly indicating the number of technical features indicated. Thus, a feature defined as "first" or "second" may explicitly or implicitly include one or more of that feature. In the description of the present invention, "a plurality" means two or more unless specifically defined otherwise.
The invention will be further explained by the description of the embodiments with reference to the drawings.
The present embodiment provides a glycated hemoglobin analyzer, as shown in fig. 1 and 2, the glycated hemoglobin analyzer includes a mounting frame 1, a chromatography mechanism 2, a detection mechanism 3, and a temperature control mechanism 4, the chromatography mechanism 2 and the detection mechanism 3 are both disposed on the mounting frame 1, the chromatography mechanism 2 is located at one side of the detection mechanism 3, and the detection mechanism 3 is connected to the chromatography mechanism 2 through a pipeline; after a sample solution to be detected is input into the chromatography mechanism 2, the sample solution is chromatographed, and then the chromatographed solution enters the detection mechanism 3 through a pipeline to be optically detected so as to obtain the absorbance of the solution, and further obtain the concentration of each component in the solution according to the absorbance. Temperature-controlled mechanism 4 is located on the mounting bracket 1, just temperature-controlled mechanism 4 is used for making the temperature of detection mechanism 3's inner chamber keeps invariable to furthest reduces the temperature drift, makes at detection mechanism 3 to the in-process that sample solution carries out optical detection, the intensity value of incident light is comparatively stable, can not make the value of incident light unstable because of the temperature drift, thereby can regard the intensity value of incident light as the definite value when calculating absorbance.
According to the invention, by arranging the temperature control mechanism 4, the influence of temperature drift on incident light can be reduced to the maximum extent, and the influence caused by temperature drift can be eliminated by detecting the main and auxiliary wavelengths of the sample solution by using two sets of detection systems, and the glycosylated hemoglobin analyzer has the advantages of simple structure and lower cost because only one set of detection mechanism 3 is arranged, and is simpler in control system and simpler in installation and debugging because one set of detection mechanism 3 is adopted.
Further, the existing algorithm for calculating the absorbance a is as follows:
where Io is the intensity of incident light, It is related to the sample solution in value, and when the concentration of hemoglobin in the sample solution to be tested is different, It is also different.
In the present embodiment, the value It of the initial optical signal is acquired at the start of the test of each sampleStarAs a background value, and the formula for calculating the absorbance is equivalent to:
since a measurement is continued for less than 1 minute in the optical measurement of glycated hemoglobin, on the other hand, the temperature drift in a short period is small by the temperature control mechanism 4, and ItStarCan be regarded as a constant value, namely:
in the above formula, the constant C does not affect the final result when calculating the percentage of glycated hemoglobin content, but can be regarded as a constant value, so that the value of absorbance ultimately depends only on the value of absorbance, and therefore, the influence of temperature drift can be further eliminated by a special algorithm converted by the above formula.
Specifically, as shown in fig. 2, the temperature control mechanism 4 includes an optical large bottom plate, an optical heating plate 42, a control mechanism 43, and a temperature sensor 44, the optical large bottom plate is disposed on the mounting frame 1 and located at the bottom of the detection mechanism 3, the optical heating plate 42 is also disposed on the mounting frame 1, the optical heating plate 42 is located at a side of the optical large bottom plate facing away from the detection mechanism 3, and the optical heating plate 42 is used for heating the optical large bottom plate; the temperature sensor 44 is located on the optical backplane, and the temperature sensor 44 is electrically connected to the control mechanism 43. When the optical heating sheet 42 is started and heats the optical large bottom plate, the temperature sensor 44 detects the heated temperature and feeds back the temperature information to the control mechanism 43 in real time, if the heated temperature does not reach the preset temperature, the control mechanism 43 controls the optical heating sheet 42 to continue heating until the temperature of the optical large bottom plate reaches the preset temperature, and the control mechanism 43 controls the optical heating sheet 42 not to heat the optical large bottom plate any more according to the feedback of the temperature sensor 44; after the temperature of the detection mechanism 3 is kept constant, the temperature sensor 44 continuously monitors the temperature, and if the temperature is lower than a preset temperature, the temperature is fed back to the control mechanism 43, and the control mechanism 43 controls the optical heating sheet 42 to heat the optical large bottom plate to the preset temperature, so that the temperature of the detection mechanism 3 is kept constant.
The control mechanism 43 comprises an upper mounting cover 431, a lower mounting cover 432 and an optical board 433, wherein the optical board 433 is used for receiving a temperature signal of the temperature sensor 44 and controlling the operation of the optical heating plate 42; the lower mounting cover 432 is connected with the upper mounting cover 431, a first accommodating cavity is formed between the lower mounting cover 432 and the upper mounting cover 431, the optical board 433 is arranged in the first accommodating cavity, and the optical board 433 is electrically connected with the temperature sensor 44 and the optical heating plate 42 respectively; the upper mounting plate is connected to the optical large base plate to fix the control mechanism 43.
A plurality of first heightening columns 5 are arranged between the optical large bottom plate and the control mechanism 43, and the control mechanism 43 is connected with the optical large bottom plate through the plurality of first heightening columns 5. For example, the upper surface of the upper mounting cover 431 is rectangular, the number of the first raised columns 5 is 4, the 4 first raised columns 5 are respectively connected to four corners of the upper surface of the upper mounting cover 431, and one end of each first raised column 5, which is far away from the upper mounting cover 431, is connected to the optical ground plate.
The mounting rack 1 is further provided with a temperature switch 7, and the temperature switch 7 extends from one side of the mounting rack 1 to be embedded into the optical large bottom plate and is electrically connected with the optical large bottom plate. The preset temperature to which the optical large floor needs to be heated is set by adjusting the temperature switch 7 so as to keep the temperature of the detection mechanism 3 at a preset constant temperature.
The detection mechanism 3 comprises an outer cover 31 and a light source detection assembly 32, the outer cover 31 is arranged on the mounting frame 1, and a second accommodating cavity is arranged in the outer cover 31; the light source detection assembly 32 is arranged on the temperature control mechanism 4, the light source detection assembly 32 is located in the second accommodating cavity, the light source detection assembly 32 is connected with the chromatographic mechanism 2 through a pipeline, a solution passing through chromatography in the chromatographic column 22 flows to the light source detection assembly 32 through the pipeline, the light source detection assembly 32 emits light to irradiate the solution flowing through the light source detection assembly 32, and the detected absorbance value is obtained. The inner wall of the second accommodating cavity can be attached with heat preservation cotton so as to provide a more constant temperature environment for the second accommodating cavity.
A support seat 8 is arranged between the light source detection assembly 32 and the optical large bottom plate, the support seat 8 is connected with the optical large bottom plate, for example, the support seat 8 is connected with the optical large bottom plate through a plurality of bolts; the lower end of the light source detection assembly 32 is fixedly connected with the upper surface of the support base 8.
The temperature control mechanism 4 is provided with a plurality of fixing assemblies 9, the fixing assemblies 9 are all arranged in the second accommodating cavity, the uniform ends of the fixing assemblies 9 are connected with the temperature control mechanism 4, and the other ends of the fixing assemblies are connected with the top of the outer cover 31. The fixing component 9 is arranged in a plurality of numbers to fix the outer cover 31. For example, there are two fixing assemblies 9, and the two fixing assemblies 9 are respectively located at two sides of the light source detection assembly 32.
Specifically, the fixing component 9 includes a vertical rod support 91 and a second heightening column 92, one end of the vertical rod support 91 is connected to the upper surface of the optical large floor, one end of the second heightening column 92 is connected to the vertical rod support 91, and the other end is connected to the top of the outer cover 31.
The chromatographic mechanism 2 comprises a mounting seat 21 and a chromatographic column 22, the mounting seat 21 is arranged on the mounting frame 1, the chromatographic column 22 is arranged in an inner cavity of the mounting seat 21, and the chromatographic column 22 is in pipeline connection with the detection mechanism 3; the inner wall of the inner cavity of the mounting seat 21 can be adhered with heat insulation cotton so as to provide a more constant temperature environment.
In summary, the present invention discloses a glycated hemoglobin analyzer, which includes: a mounting frame; the chromatography mechanism is arranged on the mounting frame; the detection mechanism is arranged on the mounting frame and is connected with the chromatography mechanism through a pipeline; and the temperature control mechanism is arranged on the mounting frame and used for keeping the temperature of the inner cavity of the detection mechanism constant. The glycosylated hemoglobin analyzer is provided with only one detection mechanism, so that the structure is simpler, the cost is lower, and the control system is simpler and the installation and debugging are simpler due to the adoption of one detection mechanism.
Finally, it should be noted that: the above examples are only intended to illustrate the technical solution of the present invention, but not to limit it; although the present invention has been described in detail with reference to the foregoing embodiments, it will be understood by those of ordinary skill in the art that: the technical solutions described in the foregoing embodiments may still be modified, or some technical features may be equivalently replaced; and such modifications or substitutions do not depart from the spirit and scope of the corresponding technical solutions of the embodiments of the present invention.
Claims (10)
1. A glycated hemoglobin analyzer, comprising:
a mounting frame;
the chromatography mechanism is arranged on the mounting frame;
the detection mechanism is arranged on the mounting frame and is connected with the chromatography mechanism through a pipeline; and
the temperature control mechanism is arranged on the mounting frame and used for keeping the temperature of the inner cavity of the detection mechanism constant.
2. The glycated hemoglobin analyzer of claim 1, wherein the temperature control mechanism comprises:
the optical large bottom plate is arranged on the mounting frame and is positioned at the bottom of the detection mechanism;
the optical heating sheet is arranged on the mounting frame, is positioned on one side, back to the detection mechanism, of the optical large bottom plate, and is used for heating the optical large bottom plate;
the control mechanism is electrically connected with the optical heating sheet; and
the temperature sensor is positioned on the optical large bottom plate and is electrically connected with the control mechanism.
3. The glycated hemoglobin analyzer of claim 2, wherein the control mechanism comprises:
the upper mounting cover is connected with the optical large bottom plate;
the lower mounting cover is connected with the upper mounting cover, and a first accommodating cavity is formed between the lower mounting cover and the upper mounting cover; and
the optical plate is clamped in the first accommodating cavity, and the optical plate is respectively electrically connected with the temperature sensor and the optical heating sheet.
4. The glycated hemoglobin analyzer as set forth in claim 2, wherein a plurality of first elevation pillars are provided between the optical large base plate and the control mechanism, and the control mechanism is connected to the optical large base plate via the plurality of first elevation pillars.
5. The glycated hemoglobin analyzer of claim 4, wherein the control mechanism is disposed on a side of the optical heating plate facing away from the optical large bottom plate, and a plurality of the receding grooves are disposed on the optical heating plate, the plurality of the receding grooves correspond to the plurality of the first raised pillars one by one, and each of the first raised pillars is disposed through the corresponding receding groove.
6. The glycated hemoglobin analyzer as set forth in claim 4, wherein a temperature switch is further provided on the mounting block, the temperature switch extending from a side of the mounting block to be embedded in and electrically connected to the optical large backplane.
7. The glycated hemoglobin analyzer of claim 1, wherein the detection mechanism comprises:
the outer cover is arranged on the mounting frame, and a second accommodating cavity is formed in the outer cover;
the light source detection assembly is arranged on the temperature control mechanism and located in the second accommodating cavity, and the light source detection assembly is connected with the chromatography mechanism through a pipeline.
8. The glycated hemoglobin analyzer of claim 7, wherein a plurality of fixing members are disposed on the temperature control mechanism, each of the plurality of fixing members is disposed in the second receiving chamber, and each of the plurality of fixing members has a uniform end connected to the temperature control mechanism and another end connected to the top of the housing.
9. The glycated hemoglobin analyzer of claim 8, wherein the fixing member comprises:
one end of the vertical rod support is connected with the temperature control mechanism;
and one end of the second heightening column is connected with the vertical rod support, and the other end of the second heightening column is connected with the top of the outer cover.
10. The glycated hemoglobin analyzer of claim 1, wherein the chromatography mechanism comprises:
the mounting seat is arranged on the mounting frame;
the chromatographic column is arranged in the inner cavity of the mounting seat and is connected with the pipeline of the detection mechanism.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202111545136.7A CN114216872A (en) | 2021-12-14 | 2021-12-14 | Glycosylated hemoglobin analyzer |
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| Application Number | Priority Date | Filing Date | Title |
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| CN202111545136.7A CN114216872A (en) | 2021-12-14 | 2021-12-14 | Glycosylated hemoglobin analyzer |
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Citations (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH09264890A (en) * | 1996-03-29 | 1997-10-07 | Tosoh Corp | Analyzing equipment of saccharified hemoglobin |
| US20070054404A1 (en) * | 2005-09-08 | 2007-03-08 | Beckman Coulter, Inc. | Method of hemoglobin correction due to temperature variation |
| US20080094623A1 (en) * | 2004-08-26 | 2008-04-24 | Koninklijke Philips Electronics N.V. | Autonomous Calibration for Optical Analysis System |
| CN204086109U (en) * | 2013-11-20 | 2015-01-07 | 杨洪民 | A kind of Portable glycosylated hemoglobin analyser |
| CN204789601U (en) * | 2015-06-09 | 2015-11-18 | 广东优尼德生物科技有限公司 | Full -automatic glycated haemoglobin analysis appearance |
| CN108778125A (en) * | 2016-03-30 | 2018-11-09 | 德克斯康公司 | Systems, devices and methods for analyte monitoring system |
| CN210442383U (en) * | 2019-06-18 | 2020-05-01 | 广东优尼德生物科技有限公司 | Chromatography separation detection device of glycosylated hemoglobin analyzer |
| CN213091692U (en) * | 2020-08-25 | 2021-04-30 | 深圳普门科技股份有限公司 | Glycosylated hemoglobin analyzer |
-
2021
- 2021-12-14 CN CN202111545136.7A patent/CN114216872A/en active Pending
Patent Citations (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH09264890A (en) * | 1996-03-29 | 1997-10-07 | Tosoh Corp | Analyzing equipment of saccharified hemoglobin |
| US20080094623A1 (en) * | 2004-08-26 | 2008-04-24 | Koninklijke Philips Electronics N.V. | Autonomous Calibration for Optical Analysis System |
| US20070054404A1 (en) * | 2005-09-08 | 2007-03-08 | Beckman Coulter, Inc. | Method of hemoglobin correction due to temperature variation |
| CN204086109U (en) * | 2013-11-20 | 2015-01-07 | 杨洪民 | A kind of Portable glycosylated hemoglobin analyser |
| CN204789601U (en) * | 2015-06-09 | 2015-11-18 | 广东优尼德生物科技有限公司 | Full -automatic glycated haemoglobin analysis appearance |
| CN108778125A (en) * | 2016-03-30 | 2018-11-09 | 德克斯康公司 | Systems, devices and methods for analyte monitoring system |
| CN210442383U (en) * | 2019-06-18 | 2020-05-01 | 广东优尼德生物科技有限公司 | Chromatography separation detection device of glycosylated hemoglobin analyzer |
| CN213091692U (en) * | 2020-08-25 | 2021-04-30 | 深圳普门科技股份有限公司 | Glycosylated hemoglobin analyzer |
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