CN113712503B - OCT probe applied to fundus operation - Google Patents
OCT probe applied to fundus operation Download PDFInfo
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- CN113712503B CN113712503B CN202111036389.1A CN202111036389A CN113712503B CN 113712503 B CN113712503 B CN 113712503B CN 202111036389 A CN202111036389 A CN 202111036389A CN 113712503 B CN113712503 B CN 113712503B
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B3/00—Apparatus for testing the eyes; Instruments for examining the eyes
- A61B3/10—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions
- A61B3/102—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions for optical coherence tomography [OCT]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B3/00—Apparatus for testing the eyes; Instruments for examining the eyes
- A61B3/0008—Apparatus for testing the eyes; Instruments for examining the eyes provided with illuminating means
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B3/00—Apparatus for testing the eyes; Instruments for examining the eyes
- A61B3/10—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions
- A61B3/12—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions for looking at the eye fundus, e.g. ophthalmoscopes
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B3/00—Apparatus for testing the eyes; Instruments for examining the eyes
- A61B3/10—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions
- A61B3/14—Arrangements specially adapted for eye photography
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Abstract
The invention discloses an OCT probe applied to fundus surgery, which comprises: the probe is provided with a lens at the far end, and the bottom surface of the lens is arc-shaped; an optical fiber disposed inside the probe with its front end tangential to the bottom surface of the lens, and the optical fiber portion being fixedly disposed inside the probe; the two groups of air passages are arranged in parallel, are symmetrically arranged at two sides of the optical fiber, and can drive the head part of the optical fiber to periodically slide along the bottom surface of the lens under the action of air flow; an air flow power device is connected with the air passage for generating a periodically changing air flow OCT system, is connected with the optical fiber, and is used for emitting and scanning guided light into a target area. The air flow is used as power to drive the front section of the optical fiber to swing laterally in the cavity of the probe, and the front section of the optical fiber is combined with the micro lens to realize the transverse scanning of the OCT beam in the front direction of the probe, so that a two-dimensional OCT structure image is obtained.
Description
Technical Field
The invention relates to the field of medical instruments, in particular to an OCT probe applied to fundus surgery.
Background
The eyeground comprises retina, optic disc and choroid, and the eyeground is the eyeground disease, which is one of the important causes of blindness. With the development of fundus surgical techniques, the treatment mode of fundus diseases gradually develops from the past conservative treatment to the surgical treatment. Fundus surgery is broadly known as posterior segment surgery, and diseases of posterior segments such as optic disc recessed macular disease, premature retinal disease macular anterior membrane, macular hole, vitreomacular traction syndrome, hole-derived retinal detachment, proliferative diabetic retinopathy, vitreovolumetric blood, posterior uveitis, and the like can be treated by surgery. The optical characteristics of the eyeball structure lead the fundus operation to be matched with a special optical imaging instrument, and the binocular indirect fundus microscope, the ocular endoscope and the OCT are widely used at present, but have advantages and disadvantages in clinical use.
1. Binocular indirect fundus microscope:
the operation microscope is the most commonly used imaging equipment in the ophthalmic operation, wherein the more commonly used binocular indirect fundus microscope is a novel non-contact wide-angle microscope, and has the advantages of wide observation angle, strong stereoscopic impression, capability of zooming, positioning observation and the like. However, the fundus microscope does not have a tomographic imaging function, and when the refractive matrix is highly turbid, the posterior pole is peeped.
2. An eye endoscope:
the endoscope imaging is a common imaging technology in ophthalmic surgery, and the traditional endoscope method overcomes the direct influence of the anterior ocular segment condition on the traditional vitreous cavity and fundus surgery, so that corneal opacity, superficial anterior chamber, anterior chamber hematocele, small pupil, lens opacity and the like can be directly observed to the surgical site under the guidance of the ophthalmic endoscope, and the surgical operation is performed. The working principle of the eye endoscope is that an image is obtained through an image pickup system, converted into an electronic signal and then transmitted to a video center, and the image is transmitted through a video display system and a television monitor. In clinic, many ophthalmic endoscopes are used to perform different diagnostic functions, but they are all planar imaging and cannot provide a tomographic structure of the retina. The method has important significance for the positioning diagnosis and operation accuracy of diseases for the retina, namely fundus tissues with rich tissue layers, different tissue functions and various lesions. For example, the operation of retinal neovascularization, retinal detachment and the like is particularly important, and the operator can clearly display the degree, level, residue and the like of lesion detachment by defining the level and range of the neovascularization through the layered structure.
3. OCT：
The optical coherence tomography (Optical Coherence Tomography, OCT) is a novel imaging technology based on the low coherence light interference principle, utilizes the coherence of scattered/reflected light and reference light of a sample arm, has the advantages of high resolution, high imaging speed and the like, fills the blank of the biomedical imaging field on the millimeter imaging depth and micrometer imaging resolution scale, and provides powerful support for the discovery, diagnosis, treatment and prognosis observation of fundus diseases. OCT currently used in surgery is often combined with a surgical microscope, and a probe beam is incident from the outside, and non-contact imaging is performed using the transparent characteristics of the eyeball. However, in the application process, if there is a non-transparent substance in the optical path of the eyeball, the propagation of the probe beam can be blocked, for example, common diseases of the eye, such as lens and vitreous opacity, or the blocking of the probe beam by the surgical instrument, can block OCT imaging, so that the fundus cannot be imaged or is not clear, and the positioning diagnosis of retinal diseases and the accuracy of operation are affected.
4. Endoscopic OCT:
combining the advantages and disadvantages of both endoscopes and OCT, various types of endoscopic OCT have been applied to clinical and research in recent years, and the different structures of scanning probes determine the application fields and different functions of OCT endoscopes.
1) Lateral scanning probe: the device has the characteristics of small structural size, flexible movement, circular scanning and the like, and is suitable for imaging hollow organs and tissues such as gastrointestinal tracts, bronchi, blood vessels and the like.
2) Forward scanning probe: the forward tissue structure information is provided, image guidance can be provided for biopsy and operation, and the method is suitable for providing tissue information for ovary, breast, brain and other solid organs.
At present, the endoscopic OCT is applied to ophthalmic imaging less, reports are frequently found in animal experiments, the endoscopic OCT is applied to human body less, and the endoscopic OCT is mainly scanned laterally, but for fundus operation, especially retinal operation, the forward tissue information is more important, so that an operator can be guided to accurately position an operation part and a hierarchical structure of the operation part.
Disclosure of Invention
Aiming at the defects of the prior art, the invention aims to provide an OCT probe applied to fundus surgery.
In order to achieve the above purpose, the present invention provides the following technical solutions:
an OCT probe for use in fundus surgery, comprising:
the probe is provided with a lens at the far end, and the bottom surface of the lens is arc-shaped;
an optical fiber disposed inside the probe with its front end tangential to the bottom surface of the lens, and the optical fiber portion being fixedly disposed inside the probe;
the two groups of air passages are arranged in parallel, are symmetrically arranged at two sides of the optical fiber, and can drive the head part of the optical fiber to periodically slide along the bottom surface of the lens under the action of air flow;
an air flow power device connected with the air passage and used for generating periodically-changing air flow;
an OCT system, coupled to the optical fiber, for emitting and scanning the guided light into the target region.
The airflow power device comprises a power generation device and a power control device.
The power generation device is a piston mechanism, the power control device is a motor, and the motor and a piston of the piston mechanism are arranged in a linkage way.
The power generation device is a vacuum pump, the power control device is a solenoid valve assembly, and the solenoid valve assembly is respectively connected with the two air passages and can switch the flow direction of air flow in the air passages.
The two sides of the optical fiber and the probe are filled and fixed by glue injection materials, and a movable space with a fan-shaped section is formed at the front end of the optical fiber.
The air passage is formed in the filled glue injection material, and the air outlets of the air passage are positioned at two sides of the front end of the unfixed optical fiber.
The optical fiber is located on the centerline of the probe.
The invention has the beneficial effects that: the air flow is used as power to drive the front section of the optical fiber to swing laterally in the cavity of the probe, and the front section of the optical fiber is combined with the micro lens to realize the transverse scanning of the OCT beam in the front direction of the probe, so that a two-dimensional OCT structure image is obtained.
Drawings
Fig. 1 is a system schematic diagram of the present invention.
Fig. 2 is a schematic structural view of embodiment 1 of the aerodynamic device of the present invention.
Fig. 3 is a schematic structural view of embodiment 2 of the aerodynamic device of the present invention.
Fig. 4 is a schematic diagram of the working principle of the invention.
Fig. 5 is a schematic diagram of the working principle of the optical fiber of the present invention when it is positioned on the left side.
Fig. 6 is a schematic diagram of the working principle of the optical fiber of the present invention when it is located on the right side.
In the figure, oct system; 2. an air flow power device; 3. a probe; 4. a light source; 5. a detector; 6. an optical coupler; 7. a reflecting mirror; 8. a power generation device; 9. a power control device; 10. a motor; 11. a piston mechanism; 12. a vacuum pump; 13. electromagnetic valve combination; 14. 15: a gas pipe; 16: an optical fiber; 17. 18: an airway; 19: a lens; 20. 21: and (5) injecting a material.
Detailed Description
The following description of the embodiments of the present invention will be made clearly and fully with reference to the accompanying drawings, in which it is evident that the embodiments described are only some, but not all embodiments of the invention. All other embodiments, which can be made by those skilled in the art based on the embodiments of the invention without making any inventive effort, are intended to be within the scope of the invention.
The invention discloses an OCT probe applied to fundus surgery, which comprises:
a probe 3, the distal end of which is provided with a lens 19, the bottom surface of which is arc-shaped, the probe comprising a handle and a needle tube, wherein the handle is configured to be held by an operator, the needle tube is formed by extending the distal end of the handle, and the end of the needle tube is provided with the lens;
the optical fiber 16 is arranged in the probe 3, the front end of the optical fiber is tangential to the bottom surface of the lens, the optical fiber part is fixedly arranged in the probe, the tail end of the optical fiber is connected with the OCT system, the optical fiber is arranged in a pipeline of the probe in a penetrating way and is completely fixed at the central position of the probe through glue injection materials 20 and 21, and a movable space with a fan-shaped section is reserved at the front end of the optical fiber, and the section is a plane in which two groups of air passages are arranged, so that the optical fiber can swing relatively freely on the coronal surface of the probe;
the two groups of air passages are arranged in parallel, are symmetrically arranged at two sides of the optical fiber, and can drive the head part of the optical fiber to periodically slide along the bottom surface of the lens under the action of air flow; two air passages 17 and 18 are symmetrically and parallelly arranged in the glue injection materials at the left side and the right side of the optical fiber, and are connected with an air flow power device through air delivery pipes 14 and 15;
an air flow power device connected with the air passage and used for generating periodically-changing air flow;
the airflow power device aims at generating the periodically-changing airflow, namely, providing power for scanning of the probe in the form of periodically-alternating airflow, and comprises a power generating device and a power control device, wherein the power generating device is used for generating the airflow serving as power, and the power control device is used for adjusting the flow direction of the airflow, and the following two embodiments are provided based on the airflow power generating device and the power control device.
Example 1
The power generation device is a piston mechanism, the power control device is a motor, the motor is in linkage with a piston of the piston mechanism, the motor 10 is used for driving the piston of the piston device 11 to reciprocate in the closed space, and therefore two gas delivery pipes connected with the probe generate air flow with periodical direction change.
Example 2
The power generation device is a vacuum pump 12, the power control device is a solenoid valve assembly 13, and the solenoid valve assembly is respectively connected with the two air passages and can switch the flow direction of air flow in the air passages. The electromagnetic valve component is used for continuously reversing the air flow in the pipeline, so that the periodic reciprocating change can be realized.
An OCT system connected to the optical fiber for emitting and scanning the guided light into the target area, the OCT system comprising a light source, a detector, an optical coupler, and a mirror, wherein the light emitted by the light source 4 enters the imaging probe through the optical coupler 6. After being reflected by tissues, OCT detection light returns through an original light path and is coupled into an optical coupler, interference is generated between the OCT detection light and light returned by a reflecting mirror 7 in a reference light path, and an interference signal is acquired by a detector 5.
The pipeline air flow is flushed out through the air pipe 14, the air pipe 17 is flushed into the top end of the probe, the optical fiber swings along with the air flow to the opposite side at the far end relative free part by means of the change of air pressure, then the air flow in the air pipe 14 is stopped, the air flow is generated in the air pipe 15 at the same time, and the optical fiber swings to the opposite direction through the air pipe 18, so that one-time scanning is completed. The scanning period of the OCT probe is the period of the change in the gas flow. Finally, the light in the fiber passes through the lens 19 to scan the fundus.
By setting the air flow change period of the air flow power device, the scanning period of the OCT probe can be adjusted, and images in the optical fiber swinging process can be acquired in a certain scanning period according to requirements.
The examples should not be construed as limiting the invention, but any modifications based on the spirit of the invention should be within the scope of the invention.
Claims (7)
1. An OCT probe for fundus surgery, characterized by: it comprises the following steps:
the probe is provided with a lens at the far end, and the bottom surface of the lens is arc-shaped;
an optical fiber disposed inside the probe with its front end tangential to the bottom surface of the lens, and the optical fiber portion being fixedly disposed inside the probe;
the two groups of air passages are arranged in parallel, are symmetrically arranged at two sides of the optical fiber, and can drive the head part of the optical fiber to periodically slide along the bottom surface of the lens under the action of air flow;
an air flow power device connected with the air passage and used for generating periodically-changing air flow;
an OCT system, coupled to the optical fiber, for emitting and scanning the guided light into the target region.
2. An OCT probe for fundus surgery according to claim 1, wherein: the airflow power device comprises a power generation device and a power control device.
3. An OCT probe for fundus surgery according to claim 2, wherein: the power generation device is a piston mechanism, the power control device is a motor, and the motor and a piston of the piston mechanism are arranged in a linkage way.
4. An OCT probe for fundus surgery according to claim 2, wherein: the power generation device is a vacuum pump, the power control device is a solenoid valve assembly, and the solenoid valve assembly is respectively connected with the two air passages and can switch the flow direction of air flow in the air passages.
5. An OCT probe for fundus surgery according to claim 1, wherein: the two sides of the optical fiber and the probe are filled and fixed by glue injection materials, and a movable space with a fan-shaped section is formed at the front end of the optical fiber.
6. An OCT probe for fundus surgery according to claim 5, wherein: the air passage is formed in the filled glue injection material, and the air outlets of the air passage are positioned at two sides of the front end of the unfixed optical fiber.
7. An OCT probe for fundus surgery according to claim 1 or 5 or 6, wherein: the optical fiber is located on the centerline of the probe.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202111036389.1A CN113712503B (en) | 2021-09-06 | 2021-09-06 | OCT probe applied to fundus operation |
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| CN202111036389.1A CN113712503B (en) | 2021-09-06 | 2021-09-06 | OCT probe applied to fundus operation |
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| CN113712503B true CN113712503B (en) | 2023-06-09 |
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Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN101444416A (en) * | 2008-12-26 | 2009-06-03 | 华中科技大学 | Fiber-optic scanning head and driving method thereof |
| CN103327875A (en) * | 2011-01-21 | 2013-09-25 | 爱尔康研究有限公司 | Combined surgical endoprobe for optical coherence tomography, illumination or photocoagulation |
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| US20050078910A1 (en) * | 2003-10-08 | 2005-04-14 | Hickingbotham Dyson W. | Surgical wide-angle illuminator |
| JP5947368B2 (en) * | 2011-03-22 | 2016-07-06 | アルコン リサーチ， リミテッド | Ophthalmic end probe |
| US9655524B2 (en) * | 2013-09-13 | 2017-05-23 | Novartis Ag | OCT probe with bowing flexor |
| US9662009B2 (en) * | 2013-12-20 | 2017-05-30 | Novartis Ag | Imaging probes and associated devices, and systems utilizing ferrofluid-impregnated actuators |
| US9668645B2 (en) * | 2014-05-09 | 2017-06-06 | Novartis Ag | Imaging probes and associated devices, systems, and methods utilizing electrostatic actuators |
| US9295384B2 (en) * | 2014-05-16 | 2016-03-29 | Novartis Ag | Imaging probes and associated devices, systems, and methods utilizing lever arm actuators |
| CN106913309B (en) * | 2015-07-31 | 2018-07-31 | 浙江大学 | Based on single all -fiber endoscopic OCT probe for drawing wimble structure |
| CN109307932A (en) * | 2017-07-27 | 2019-02-05 | 成都理想境界科技有限公司 | A kind of fibre-optic scanner |
| CN109875504B (en) * | 2019-01-15 | 2021-07-30 | 温州医科大学 | Method for non-invasively measuring corneal viscoelasticity based on jet optical coherence elastography technology |
| CN113017554B (en) * | 2021-02-05 | 2023-05-23 | 温州医科大学 | Imaging method and device for dynamic optical coherence tomography image of human eye atrial corner |
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Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101444416A (en) * | 2008-12-26 | 2009-06-03 | 华中科技大学 | Fiber-optic scanning head and driving method thereof |
| CN103327875A (en) * | 2011-01-21 | 2013-09-25 | 爱尔康研究有限公司 | Combined surgical endoprobe for optical coherence tomography, illumination or photocoagulation |
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