CN113171555A - Device for treating cancer by electric field and device using method - Google Patents
Device for treating cancer by electric field and device using method Download PDFInfo
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- 206010028980 Neoplasm Diseases 0.000 title claims abstract description 74
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- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/36002—Cancer treatment, e.g. tumour
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/36014—External stimulators, e.g. with patch electrodes
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/36014—External stimulators, e.g. with patch electrodes
- A61N1/3603—Control systems
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Abstract
The invention provides a device for treating cancer by an electric field and a using method of the device, wherein the device comprises a control module, an electric field generator, a pair of electrode patches, an electric field identification module, an electric field receiver and a magnetic field array; the electrode patches are arranged on two outer surfaces of a tumor position of a human body and used for receiving an electric field of the magnetic field array; the electric field identification module is fixedly attached to one of the electrode patches to identify the electric field intensity and direction of the current electrode in the magnetic field array acting on the human body; the electrode patch and the electric field identification module are both connected with the control module; the electric field generator is connected with each electrode of the magnetic field array to generate a treatment electric field; the control module judges whether the electric field intensity and the direction of the current electrode acting on the human body meet the treatment requirements, if not, the electrode is rescanned and switched to the electrode meeting the treatment requirements. Based on the device, a device using method is also provided. The wearable freely-moving mode is adopted, the electric field is used for treating the cancer, and the treatment position does not deviate.
Description
Technical Field
The invention belongs to the technical field of cancer electrotherapy equipment, and particularly relates to a device for treating cancer by an electric field and a use method of the device.
Background
The electric field therapy for tumor is a therapy implemented by a portable and non-invasive medical apparatus, and the principle is that a low-intensity medium-frequency (200kHz) alternating-current electric field acts on tubulin proliferating cancer cells to interfere mitosis of the cancer cells, so that the affected cancer cells are apoptotic and tumor growth is inhibited. By means of the mode of local application and the antimitotic effect, compared with traditional treatment means such as operation, radiotherapy and drug treatment, the tumor electric field treatment has smaller side effect, and the effectiveness of the tumor electric field treatment is strictly clinically verified. Compared with the traditional cancer treatment mode, the tumor electric field treatment has an innovative action mechanism. Some of the physiological properties of tumor cells, such as geometry and high frequency mitosis, make them susceptible to tumor electric field therapy. Tumor electric field therapy disrupts the normal aggregation of tubulin by exerting a directed force on intracellular polar particles (e.g., macromolecules and organelles). These processes may lead to physical disruption of the cell membrane and apoptosis. At the terminal stage of mitosis of the cell, the structural form of the cleavage furrow can cause uneven distribution of electric fields around the cell, and meanwhile, under the influence of tumor electric field treatment, the electric field intensity at the cleavage furrow is obviously enhanced, and charged substances in the cell move to the cleavage furrow, so that the formation of the cell structure is interfered and even damaged, and finally, the cell can fail to divide and go to apoptosis.
The principle is utilized to treat brain glioma at the earliest time, the fixed electrode is arranged on the hat, the alternating electric field acts on the brain of a person, the life span of the person is prolonged by 13%, and the principle is utilized to treat breast cancer or lung cancer and has corresponding effect. The electric field treatment of tumors is a cumulative effect for a long time, and the longer the wearing time is, the better. However, in the prior art, various major medical device companies research some wearable devices for treating cancer, such as underwear, caps, and the like, which are in a fixed electrode manner, and can be worn by people when they are awake in the daytime, but at night, if people continue to wear the fixed electrode device while they are at rest, they feel abnormal discomfort, and if the position of the fixed electrode device is shifted, they will not have a therapeutic effect.
Disclosure of Invention
In order to solve the technical problems, the invention provides a device for treating cancer by an electric field and a use method of the device, which adopt a wearable freely moving mode to treat cancer by the electric field, increase the time of treating tumors by the electric field, prevent the treatment position from shifting and enhance the diagnosis and treatment effect.
In order to achieve the purpose, the invention adopts the following technical scheme:
a device for treating cancer by an electric field comprises a control module, an electric field generator, a pair of electrode patches, an electric field identification module, an electric field receiver and a magnetic field array;
the electrode patches are arranged on two outer surfaces of a tumor position of a human body and used for receiving an electric field of the magnetic field array; the electric field identification module is fixedly attached to one of the electrode patches and is used for identifying the electric field intensity and the direction of the current electrode in the magnetic field array acting on the human body; the electrode patch and the electric field identification module are connected with the control module through an electric field receiver; the electric field generator is connected with each electrode of the magnetic field array; emitting an electric field acting to treat the cancer through each electrode of the magnetic field array;
the control module is also connected with the electric field generator and used for judging whether the electric field intensity and the direction of the current electrode acting on the human body simultaneously meet the treatment requirements, if not, the magnetic field array is rescanned, and the electrode which meets the treatment requirements is switched to act on the position of the tumor of the human body.
Further, the magnetic field array comprises a first magnetic field array and a second magnetic field array; the first magnetic field array is arranged on an article which covers the human body when sleeping; the second magnetic field array is mounted on an article that is padded under the body during sleep.
Further, the first magnetic field array comprises 16 electrodes; and 16 electrodes are distributed in a 4 x 4 array.
Further, the second magnetic field array comprises 16 electrodes; and 16 electrodes are distributed in a 4 x 4 array.
Further, the magnetic field array is arranged on the clothes.
Further, the electric field identification module comprises 6 electrodes, and the electric field identification module is of a spherical structure; taking the center of the sphere as an origin, the first electrode is positioned in the positive direction of the X axis, and the second electrode is positioned in the negative direction of the X axis; the third electrode is positioned in the positive direction of the Y axis, and the fourth electrode is positioned in the negative direction of the Y axis; the fifth electrode is positioned in the positive direction of the Z axis, and the sixth electrode is positioned in the negative direction of the Z axis; the first electrode and the second electrode are symmetrically arranged; the third electrode and the fourth motor are symmetrically arranged; the fifth electrode and the sixth electrode are symmetrically arranged.
Further, the electric field receiver is in communication connection with the electric field identification module in a wired or wireless mode; the electric field receiver is used for filtering and denoising the electric field signal acquired by the electric field identification module to obtain a pre-processed electric signal of 100KHz to 300KHz, and transmitting the obtained pre-processed electric signal of 100KHz to 300KHz to a receiving port of the control module.
Furthermore, the control module adopts a PLC, a single chip microcomputer or a microcontroller.
The use method of the device for treating the cancer by the electric field is realized on the basis of the device for treating the cancer by the electric field, and comprises the following steps:
acquiring the voltage magnitude and direction of a preprocessing electric signal acted on a human body by a current electrode;
judging whether the voltage magnitude and the direction of the preprocessed electric signal meet the voltage magnitude and the direction of the signal required by treatment; rescanning the magnetic field array if either the magnitude or the direction does not meet the requirements; judging whether the voltage and the direction of the electric field emitted by other electrodes meet the magnitude and the direction of the voltage required by treatment;
switching to the electrode meeting the treatment requirement.
Further, the judging whether the magnitude and the direction of the voltage of the preprocessed electric signal meet the magnitude and the direction of the voltage of the signal required by the treatment comprises: and judging whether the voltage of the preprocessed electric signal is in the voltage range of the signal required by treatment or not, and whether the direction of the voltage of the preprocessed electric signal is the same as the direction of the voltage required by treatment or not.
The effect provided in the summary of the invention is only the effect of the embodiment, not all the effects of the invention, and one of the above technical solutions has the following advantages or beneficial effects:
the invention provides a device for treating cancer by an electric field and a using method thereof, aiming at the mode of adopting fixed electrodes for treatment disclosed in the prior art, the device for treating cancer by the electric field disclosed by the invention comprises a control module, an electric field generator, a pair of electrode patches, an electric field identification module, an electric field receiver and a magnetic field array; the electrode patches are arranged on two outer surfaces of a tumor position of a human body and used for receiving an electric field of the magnetic field array; the electric field identification module is fixedly attached to one of the electrode patches and is used for identifying the electric field intensity and the direction of the current electrode in the magnetic field array acting on the human body; the electrode patch and the electric field identification module are connected with the control module through an electric field receiver; the electric field generator is connected with each electrode of the magnetic field array; emitting an electric field acting to treat the cancer through each electrode of the magnetic field array; the control module is also connected with the electric field generator and used for judging whether the electric field intensity and the direction of the current electrode acting on the human body simultaneously meet the treatment requirements, if not, the magnetic field array is rescanned, and the electrode which meets the treatment requirements is switched to act on the position of the tumor of the human body. The invention also provides a device for treating the cancer by the electric field and a use method thereof based on the device for treating the cancer by the electric field. The wearable freely-moving mode is adopted, the electric field is used for treating the cancer, the time for treating the tumor by the electric field is prolonged, the treatment position does not deviate, and the diagnosis and treatment effect is enhanced.
The invention also discloses a structure of the electric field identification module, the electric field identification module has a simple structure, is easy to realize, is attached to the outer surface of the cancer tumor position of the human body, and provides technical support for the free movement of the invention.
Drawings
FIG. 1 is a schematic connection diagram of an electric field cancer treatment apparatus according to embodiment 1 of the present invention;
fig. 2 is a schematic structural diagram of the magnetic field array mounted on the bedding article according to embodiment 1 of the present invention;
fig. 3 is a schematic structural diagram of an electric field identification module according to embodiment 1 of the present invention;
fig. 4 is a flowchart of a method for using an apparatus for treating cancer by electric field according to embodiment 3 of the present invention.
Detailed Description
In order to clearly explain the technical features of the present invention, the following detailed description of the present invention is provided with reference to the accompanying drawings. The following disclosure provides many different embodiments, or examples, for implementing different features of the invention. To simplify the disclosure of the present invention, the components and arrangements of specific examples are described below. Furthermore, the present invention may repeat reference numerals and/or letters in the various examples. This repetition is for the purpose of simplicity and clarity and does not in itself dictate a relationship between the various embodiments and/or configurations discussed. It should be noted that the components illustrated in the figures are not necessarily drawn to scale. Descriptions of well-known components and processing techniques and procedures are omitted so as to not unnecessarily limit the invention.
Example 1
Embodiment 1 of the present invention provides an apparatus for treating cancer by electric field, and fig. 1 shows a connection schematic diagram of an apparatus for treating cancer by electric field in embodiment 1 of the present invention. The device comprises a control module, an electric field generator, a pair of electrode patches, an electric field identification module, an electric field receiver and a magnetic field array;
the electrode patches are arranged on two outer surfaces of a tumor position of a human body and used for receiving an electric field of the magnetic field array; the electric field identification module is fixedly attached to one of the electrode patches and is used for identifying the electric field intensity and the direction of the current electrode in the magnetic field array acting on the human body; the electrode patch and the electric field identification module are connected with the control module through an electric field receiver; the electric field generator is connected with each electrode of the magnetic field array; emitting an electric field acting to treat the cancer through each electrode of the magnetic field array;
the control module is also connected with the electric field generator and used for judging whether the electric field intensity and the direction of the current electrode acting on the human body simultaneously meet the treatment requirements, if not, the magnetic field array is rescanned, the electrode which meets the treatment requirements is switched to act on the outer surface of the human tumor position, and the electric field identification module is fixedly attached to the outer surface of the human tumor position and used for identifying the electric field intensity and the direction of the current electrode acting on the human body.
When the device for treating cancer by using the electric field is used for treating when people are at rest in embodiment 1 of the invention. Fig. 2 is a schematic structural diagram of the magnetic field array mounted on the bedding article according to embodiment 1 of the present invention; the magnetic field array comprises a first magnetic field array and a second magnetic field array; the first magnetic field array is arranged on an article which covers the human body when sleeping; generally including quilts, blankets, etc.; the second magnetic field array is mounted on an article that is placed under the body during sleep, and typically includes a mattress, sheet.
The first magnetic field array comprises 16 electrodes; and 16 electrodes are distributed in a 4 x 4 array. The second magnetic field array comprises 16 electrodes; and 16 electrodes are distributed in a 4 x 4 array. The number of magnetic field arrays to be protected in embodiment 1 of the present invention can be set according to the needs of people, and the number of protection of the present invention is not limited to the number listed in embodiment 1.
A pair of electrode patches is typically mounted on each of the two outer surfaces of the tumor at the site of the tumor. For example, the outer surfaces of the chest and the back of a human body, and the electric field identification module is fixedly attached to the outer part of one of the electrode patches and is used for identifying the electric field intensity and the direction of the current electrode acting on the human body in the magnetic field array. Fig. 3 is a schematic structural diagram of an electric field identification module according to embodiment 1 of the present invention; the electric field identification module is arranged in a spherical shape, and encapsulates a spherical device, so that direction differences exist when the electric field identification module is attached to a human body.
The electric field recognition module adopts 6 electrodes, wherein the first electrode is positioned in the positive direction of an X axis, and the second electrode is positioned in the negative direction of the X axis; the third electrode is positioned in the positive direction of the Y axis, and the fourth electrode is positioned in the negative direction of the Y axis; the fifth electrode is located in the positive direction of the Z axis, and the sixth electrode is located in the negative direction of the Z axis. The first electrode and the second electrode are symmetrically arranged by taking the sphere center as a reference; the third electrode and the fourth motor are symmetrically arranged by taking the sphere center as a reference; the fifth electrode and the sixth electrode are symmetrically arranged with respect to the center of the sphere.
The electric field receiver is in communication connection with the electric field identification module in a wired or wireless mode; the electric field receiver is used for filtering and denoising the electric field signal acquired by the electric field identification module to obtain a pre-processed electric signal of 100KHz to 300KHz, and transmitting the obtained pre-processed electric signal of 100KHz to 300KHz to a receiving port of the control module. The control module adopts a PLC, a singlechip or a microcontroller and the like. The amount of protection according to the invention is not limited to the kind listed in example 1.
Example 2
The embodiment 2 of the invention also provides a device for treating cancer by using an electric field, which comprises a control module, an electric field generator, a pair of electrode patches, an electric field identification module, an electric field receiver and a magnetic field array;
the electrode patches are arranged on two outer surfaces of a tumor position of a human body and used for receiving an electric field of the magnetic field array; the electric field identification module is fixedly attached to one of the electrode patches and is used for identifying the electric field intensity and the direction of the current electrode in the magnetic field array acting on the human body; the electrode patch and the electric field identification module are connected with the control module through an electric field receiver; the electric field generator is connected with each electrode of the magnetic field array; emitting an electric field acting to treat the cancer through each electrode of the magnetic field array;
the control module is also connected with the electric field generator and used for judging whether the electric field intensity and the direction of the current electrode acting on the human body simultaneously meet the treatment requirements, if not, the magnetic field array is rescanned, the electrode which meets the treatment requirements is switched to act on the outer surface of the human tumor position, and the electric field identification module is fixedly attached to the outer surface of the human tumor position and used for identifying the electric field intensity and the direction of the current electrode acting on the human body.
The electric field device for treating cancer has magnetic field array mounted on the clothes. The number of the magnetic field arrays can be set according to the requirement, and a plurality of magnetic field arrays are respectively arranged on the chest part and the back part of the clothes.
The electric field identification module is fixedly attached to the outer surface of the tumor position of the human body and used for identifying the electric field intensity and direction of the current electrode acting on the human body.
The structure schematic diagram of the electric field identification module disclosed in the embodiment 1 of the invention and the figure 3 is adopted; the electric field identification module is arranged in a spherical shape, and encapsulates a spherical device, so that direction differences exist when the electric field identification module is attached to a human body.
The electric field recognition module adopts 6 electrodes, wherein the first electrode is positioned in the positive direction of an X axis, and the second electrode is positioned in the negative direction of the X axis; the third electrode is positioned in the positive direction of the Y axis, and the fourth electrode is positioned in the negative direction of the Y axis; the fifth electrode is located in the positive direction of the Z axis, and the sixth electrode is located in the negative direction of the Z axis. The first electrode and the second electrode are symmetrically arranged by taking the sphere center as a reference; the third electrode and the fourth motor are symmetrically arranged by taking the sphere center as a reference; the fifth electrode and the sixth electrode are symmetrically arranged with respect to the center of the sphere.
The electric field receiver is in communication connection with the electric field identification module in a wired or wireless mode; the electric field receiver is used for filtering and denoising the electric field signal acquired by the electric field identification module to obtain a pre-processed electric signal of 100KHz to 300KHz, and transmitting the obtained pre-processed electric signal of 100KHz to 300KHz to a receiving port of the control module. The control module adopts a PLC, a singlechip or a microcontroller and the like. The amount of protection according to the invention is not limited to the kind listed in example 2.
Example 3
Based on the device for treating cancer by using electric field disclosed in embodiment 1 and embodiment 2 of the invention, embodiment 2 of the invention provides a method for using the device for treating cancer by using electric field. Fig. 4 is a flowchart of a method for using an apparatus for treating cancer by electric field according to embodiment 3 of the present invention.
In step S401, the magnitude and direction of the voltage of the pre-processed electrical signal applied to the human body by the current electrode are obtained. In the step, the electric field identification module identifies the electric field intensity and the direction of the current electrode acting on the human body. When the electric field strength is 2V/ms, the requirement of treating cancer is met. An electric field signal identified by the electric field identification module is transmitted to a receiving port of the control module through an electric field receiver, and the electric field receiver is in communication connection with the electric field identification module in a wired or wireless mode; the electric field receiver is used for filtering and denoising the electric field signal acquired by the electric field identification module to obtain a preprocessed electric signal of 100KHz to 300 KHz. Receiving port of control module receives preprocessed electric signal
In step S402, the control module determines whether the magnitude and direction of the voltage of the preprocessed electrical signal meet the magnitude and direction of the voltage of the signal required for treatment; if either the size or the direction does not meet the requirement, other electrodes of the magnetic field array are rescanned;
in the invention, judging whether the voltage magnitude and the direction of the preprocessed electric signal meet the therapeutic requirement comprises the following steps: and judging whether the voltage of the preprocessed electric signal is in the voltage range of the signal required by treatment or not, and whether the direction of the voltage of the preprocessed electric signal is the same as the direction of the voltage required by treatment or not.
In step S403, determining whether the voltage and direction of the electric field emitted by the other electrode satisfy the voltage and direction required for treatment;
in step S404, the electrode satisfying the treatment requirement is switched.
In the method for using the device for treating cancer by using an electric field provided in embodiment 3 of the present invention, the control module is used to determine whether the current electrode meets the treatment requirement, and if not, the current electrode is switched to the electrode meeting the treatment requirement. The wearable freely-moving mode is adopted, the electric field is used for treating the cancer, the time for treating the tumor by the electric field is prolonged, the treatment position does not deviate, and the diagnosis and treatment effect is enhanced.
Although the embodiments of the present invention have been described with reference to the accompanying drawings, the scope of the present invention is not limited thereto. Various modifications and alterations will occur to those skilled in the art based on the foregoing description. And are neither required nor exhaustive of all embodiments. On the basis of the technical scheme of the invention, various modifications or changes which can be made by a person skilled in the art without creative efforts are still within the protection scope of the invention.
Claims (10)
1. The device for treating the cancer by the electric field is characterized by comprising a control module, an electric field generator, a pair of electrode patches, an electric field identification module, an electric field receiver and a magnetic field array;
the electrode patches are arranged on two outer surfaces of a tumor position of a human body and used for receiving an electric field of the magnetic field array; the electric field identification module is fixedly attached to one of the electrode patches and is used for identifying the electric field intensity and the direction of the current electrode in the magnetic field array acting on the human body; the electrode patch and the electric field identification module are connected with the control module through an electric field receiver; the electric field generator is connected with each electrode of the magnetic field array; emitting an electric field acting to treat the cancer through each electrode of the magnetic field array;
the control module is also connected with the electric field generator and used for judging whether the electric field intensity and the direction of the current electrode acting on the human body simultaneously meet the treatment requirements, if not, the magnetic field array is rescanned, and the electrode which meets the treatment requirements is switched to act on the position of the tumor of the human body.
2. The device of claim 1, wherein the magnetic field array comprises a first magnetic field array and a second magnetic field array; the first magnetic field array is arranged on an article covered on the human body; the second magnetic field array is mounted on an article that is padded underneath the body.
3. The device of claim 2, wherein said first magnetic field array comprises 16 electrodes; and 16 electrodes are distributed in a 4 x 4 array.
4. The device of claim 3, wherein said second magnetic field array comprises 16 electrodes; and 16 electrodes are distributed in a 4 x 4 array.
5. The device of claim 1, wherein the array of magnetic fields is disposed on clothing.
6. The device for electric field therapy of cancer according to claim 1, wherein said electric field identification module comprises 6 electrodes, and said electric field identification module is a spherical structure; taking the center of the sphere as an origin, the first electrode is positioned in the positive direction of the X axis, and the second electrode is positioned in the negative direction of the X axis; the third electrode is positioned in the positive direction of the Y axis, and the fourth electrode is positioned in the negative direction of the Y axis; the fifth electrode is positioned in the positive direction of the Z axis, and the sixth electrode is positioned in the negative direction of the Z axis; the first electrode and the second electrode are symmetrically arranged; the third electrode and the fourth motor are symmetrically arranged; the fifth electrode and the sixth electrode are symmetrically arranged.
7. The device for electric field therapy of cancer according to claim 1, wherein said electric field receiver is connected to said electric field identification module by wire or wireless communication; the electric field receiver is used for filtering and denoising the electric field signal acquired by the electric field identification module to obtain a pre-processed electric signal of 100KHz to 300KHz, and transmitting the obtained pre-processed electric signal of 100KHz to 300KHz to a receiving port of the control module.
8. The device for electric field therapy of cancer according to claim 1, wherein said control module is a PLC, a single chip or a microcontroller.
9. An electric field cancer treatment device using method is realized based on the electric field cancer treatment device of any one of claims 1 to 8, and is characterized by comprising the following steps:
acquiring the voltage magnitude and direction of a preprocessing electric signal acted on a human body by a current electrode;
judging whether the voltage magnitude and the direction of the preprocessed electric signal meet the voltage magnitude and the direction of the signal required by treatment; rescanning the magnetic field array if either the magnitude or the direction does not meet the requirements; judging whether the size and the direction of the electric field emitted by other electrodes meet the size and the direction of voltage required by treatment;
switching to the electrode meeting the treatment requirement.
10. The method of claim 9, wherein said determining whether the voltage level and direction of the pre-processed electrical signal satisfy the voltage level and direction of the signal required for treatment comprises: and judging whether the voltage of the preprocessed electric signal is in the voltage range of the signal required by treatment or not, and whether the direction of the voltage of the preprocessed electric signal is the same as the direction of the voltage required by treatment or not.
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113082519A (en) * | 2021-04-30 | 2021-07-09 | 杭州维那泰克医疗科技有限责任公司 | Device for destroying or inhibiting division of diseased cells and control method thereof |
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