CN113116347A

CN113116347A - Biological information sensing patch

Info

Publication number: CN113116347A
Application number: CN201911391273.2A
Authority: CN
Inventors: 黄清俊; 陈怡仁; 陈一飞
Original assignee: Zhizhun Shengyi Technology Co ltd
Current assignee: Zhizhun Shengyi Technology Co ltd
Priority date: 2019-12-30
Filing date: 2019-12-30
Publication date: 2021-07-16

Abstract

A biological information sensing patch comprises a shell, a plurality of electrode plates, an electronic device, a plurality of electric connection plates and a power supply unit. The electrode plates are electrically independent from each other and expose at least one sensing end outside the shell. The electronic device comprises a substrate and a signal processing element. The substrate comprises a plurality of first conductive contacts and a plurality of second conductive contacts. The signal processing element is arranged on the substrate and electrically connected with the first conductive contact. One connecting end of each electric connecting sheet is connected with the electrode sheet, and one contact end of each electric connecting sheet abuts against the second conductive contact of the substrate. The power supply unit provides power supply for the electronic device to operate. The biological information sensing patch can simplify the number of parts and the assembly process.

Description

Biological information sensing patch

Technical Field

The invention relates to a sensing patch, in particular to a biological information sensing patch.

Background

In the prior art, biological information (such as blood sugar) is obtained by a medical staff needle or a user punctures skin by himself to obtain a small amount of blood and then performs chemical analysis. Such a measurement method is only biological information obtained at a single time point, and if the measurement is intensive, not only is the inconvenience of an operator caused, but also the subject is caused to feel more pain, and further, the rejection is generated or the number of times of measurement is reduced.

In order to overcome the above problems, a bioinformation sensing patch has been developed which can be attached to the skin of a living body, reduce pain of a subject by low invasive puncture, and obtain tissue fluid, thereby continuously obtaining bioinformation of the subject for a long time. The conventional biological information sensing patch electrically connects the sensing electrode with the substrate of the electronic element by soldering or other electrical connection elements (such as elastic pins, conductive adhesive material, etc.). Such a structure not only increases the number of parts, but also makes the assembly process complicated.

In view of the above, it is an object of great efforts to simplify the number of parts and the assembly process of the biological information sensing patch.

Disclosure of Invention

The invention provides a biological information sensing patch, which is connected with an electrode plate by an electric connecting sheet and is electrically connected with a substrate of an electronic device in a physical abutting mode, so that the number of parts and the assembly process can be simplified.

The biological information sensing patch of an embodiment of the invention includes a housing, a plurality of electrode pads, an electronic device, a plurality of electrical connection pads, and a power unit. The housing comprises an upper cover and a lower cover, wherein the upper cover and the lower cover define an accommodating space, and the lower cover comprises a plurality of openings. The electrode plates are arranged in the accommodating space and are electrically independent from each other, wherein each electrode plate comprises at least one sensing end, and the sensing end corresponds to the opening so as to expose the sensing end to be used as a working electrode or a reference electrode. The electronic device is arranged in the accommodating space and comprises a substrate and a signal processing element. The substrate comprises a plurality of first conductive contacts and a plurality of second conductive contacts, and the first conductive contacts are electrically connected with the corresponding first conductive contacts. The signal processing element is arranged on the substrate and electrically connected with the first conductive contact. One connecting end of each electric connecting sheet is connected with the corresponding electrode sheet, and one contact end of each electric connecting sheet abuts against the corresponding second conductive contact of the substrate. The power supply unit is electrically connected with the electronic device to provide power supply for the operation of the electronic device.

The purpose, technical content, features and effects of the present invention will be more readily understood by the following detailed description of the embodiments taken in conjunction with the accompanying drawings.

Drawings

Fig. 1 is a schematic view illustrating a biological information sensing patch according to an embodiment of the present invention;

fig. 2 is a schematic view illustrating an exploded structure of a biological information sensing patch according to an embodiment of the present invention;

fig. 3a to 3g are schematic views illustrating an electrode sheet and an electrical connection sheet of a biological information sensing patch according to an embodiment of the present invention;

fig. 4 and 5 are schematic views showing a lower cover and an electrode sheet of a biological information sensing patch according to another embodiment of the present invention;

FIG. 6 is a schematic view showing a lower cover and an electrode pad of a biological information sensing patch according to still another embodiment of the present invention;

fig. 7 is a schematic diagram illustrating a signal processing element of a biological information sensing patch according to an embodiment of the invention.

Description of the symbols

1 biological information sensing patch

11 outer cover

111 upper cover

112 lower cover

1121 opening of a hole

1122 limiting structure

12 electrode slice

12 a-12 d electrode slice

121 sensing terminal

122 fold

123 projection

13 electronic device

131 base plate

1311 first conductive contact

1312 second conductive contact

132 signal processing element

1321 microprocessor

1322 memory cell

1323 communication interface

132a conductive bump

132b lead wire

14 electric connection sheet

141 contact terminal

15 Power supply unit

Detailed Description

The following detailed description of the embodiments of the invention is provided in connection with the accompanying drawings. Aside from the details given herein, this invention is capable of broad application to other embodiments and that various other substitutions, modifications, and equivalents may be made in the embodiments without departing from the scope of the invention as defined by the appended claims. In the description of the specification, numerous specific details are set forth in order to provide a more thorough understanding of the invention; however, the present invention may be practiced without some or all of these specific details. In other instances, well-known steps or elements have not been described in detail so as not to unnecessarily obscure the present invention. The same or similar elements in the drawings will be denoted by the same or similar symbols. It is noted that the drawings are for illustrative purposes only and do not represent actual sizes or quantities of elements, and some details may not be drawn completely to simplify the drawings.

Referring to fig. 1 and 2, a biological information sensing patch 1 according to an embodiment of the invention includes a housing 11, a plurality of electrode pads 12, an electronic device 13, a plurality of electrical connection pads 14, and a power unit 15. The housing 11 includes an upper cover 111 and a lower cover 112, and the upper cover 111 and the lower cover 112 define an accommodating space, wherein the lower cover 112 includes a plurality of openings 1121. The upper cover 111 and the lower cover 112 may be made of the same material or different materials. In one embodiment, the lower cover 112 may be a semi-soft material with adhesive properties, which can be tightly attached to the skin surface of a human body, such as an artificial skin. In another embodiment, the cover 111 may be a semi-soft material without adhesive property, and can be pressed by the user to form a suitable streamline structure, so as to reduce the resistance of the biological information sensing patch 1 from impacting in various directions. In another embodiment, the upper cover 111 and the lower cover 112 may be made of hard material and semi-soft material to ensure the size and shape of the accommodating space, and can be closely attached to the skin surface of the human body and/or reduce the resistance of the biological information sensing patch 1 from impacting in various directions.

Continuing with the above description, the plurality of electrode pads 12 are disposed in the accommodating space of the housing 11 and electrically independent from each other. Each electrode sheet 12 includes at least one sensing end 121, and the sensing end 121 corresponds to the opening 1121 of the bottom cover 112. The exposed sensing tip 121 may be in contact with a skin tissue layer or skin surface to serve as a working electrode or a reference electrode. In one embodiment, the electrode sheets 12 include at least one working electrode, at least one reference electrode, and at least one counter electrode. The sensing layer coated on the surface of the sensing end 121 can convert biological information (such as blood sugar, lactic acid or concentration of a specific drug) into an electronic signal. The sensing layer may be a composite or a multi-layer structure. For example, in the case of measuring blood glucose (glucose), the sensing layer includes glucose oxidase and/or glucose dehydrogenase. The sensing tip 121 shown in fig. 1 and 2 is in the shape of a sharp needle, which can penetrate into the skin tissue layer of a biological subject, so that the sensing layer coated on the surface of the sensing tip 121 reacts with the tissue fluid or blood of the skin tissue layer to measure the biological information in the tissue fluid or blood. In one embodiment, the sensing end can be a convex point or a plane, and the sensing end is contacted with the surface of the skin during measurement so as to measure the biological information of saliva, tears, sweat or the surface of the skin.

As described above, the electronic device 13 is disposed in the accommodating space of the housing 11. The electronic device 13 includes a substrate 131 and a signal processing element 132. The substrate 131 includes a plurality of first conductive contacts 1311 and a plurality of second conductive contacts 1312, wherein each of the second conductive contacts 1312 is electrically connected to a corresponding first conductive contact 1311 through an interconnection (not shown) of the substrate 131. The signal processing element 132 is disposed on the substrate 131 and electrically connected to the first conductive contact 1311 of the substrate 131. For example, the signal processing element 132 may be electrically connected to the first conductive contact 1311 of the substrate 131 through the conductive bump 132a or the lead 132 b. A connecting end of each electrical connecting sheet 14 is connected to the corresponding electrode pad 12, and a contact end 141 of each electrical connecting sheet 14 abuts against the corresponding second conductive contact 1312 of the substrate 131. The power unit 15 is electrically connected to the electronic device 13 to provide power for the electronic device 13 to operate.

In one embodiment, the electrode pads 12 and the electrical connection pads 14 are integrally formed elements, such as by stamping. The integrally formed component can be manufactured through a continuous die stamping process, and a coil stock is equidistantly sent to each independent engineering station in a die by a feeder to be stamped and processed, and then the product is finished at the final engineering station. According to this structure, the electrical connection sheet 14 can make the contact end 141 abut against the second conductive contact 1312 of the substrate 131 by the deformed restoring force to form a conductive path. Therefore, the biological information sensing patch of the present invention does not need to electrically connect the electrodes and the electronic device by soldering or other electrical connection elements (e.g., pogo pins, conductive paste materials, etc.), so as to simplify the number of parts and the assembly process, and can be mass-produced automatically. In one embodiment, the electrode pads 12 and the electrical connection pads 14 may be made of stainless steel, nickel alloy, titanium or titanium alloy.

Referring to fig. 3a to 3g, the structure of the electrode pads 12 and the electrical connection pads 14 will be described. Referring to fig. 3a, the electrode sheet 12 includes at least one folded edge 122, and the sensing end 121 is disposed at the top end of the folded edge 122. The flange 122 of the electrode tab 12 fits into the opening 1121 of the lower cover 112 to prevent the electrode 12 from slipping. In an embodiment, referring to fig. 3b, the electrode sheet 12 may also directly extend out of the sensing end 121 and be bent downward, so as to omit the folded edge 122 shown in fig. 3 a.

In the embodiment shown in fig. 3a and 3b, the electrical connection tab 14 extends outwardly from the electrode tab 12, but is not limited thereto. In one embodiment, as shown in fig. 3c, the electrical connection sheet 14 may also be bent toward the electrode pad 12, such that the contact end 141 of the electrical connection sheet 14 and the sensing end 121 of the electrode pad 12 are located on different sides of the electrode pad 12. According to this structure, more sensing terminals 121 can be disposed in a unit area.

Referring to fig. 3d, in an embodiment, the electrode sheet 12 may be connected to a plurality of electrical connection sheets 14. According to this structure, the plurality of electrical connection tabs 14 can balance the pressure applied to the electrode pads 12 by the substrate 131, and can improve the reliability of the electrical connection of the electrode pads 12.

In the above embodiments, the contact end 141 of the electrical connection sheet 14 is a bevel, but not limited thereto. For example, referring to fig. 3e, the contact end 141 of the electrical connection sheet 14 may also be a cambered surface. It is understood that the contact end 141 is a bent angle or a curved surface, and the contact area with the second conductive contact 1312 is larger than that of the electrical connection element such as the thimble in the prior art, so that the reliability of the electrical connection can be improved. In one embodiment, referring to fig. 3f, by proper processing, a plurality of contact terminals 141 can be formed on a single electrical connection sheet 14, which also has the effect of improving the reliability of electrical connection.

In the foregoing embodiment, the electrical connection sheet 14 extends from the electrode sheet 12 to the outside and then is bent toward the electrode sheet 12, but is not limited thereto. In one embodiment, please refer to fig. 3g, which is a cross-sectional structure of the electrical connection sheet 14. As shown in fig. 3g, the electrical connection sheet 14 is a contact end 141 bent upward from the inside of the electrode sheet 12. According to the structure, the electrode plate 12 and the electric connecting sheet 14 which are integrally formed have the effects of saving materials and increasing the distribution density of the electrode plate 12.

In an embodiment, referring to fig. 4 and 5, the lower cover 112 includes at least one position-limiting structure 1122 disposed in the opening 1121, and the folded edge 122 of the electrode tab 12 has at least one corresponding protrusion 123. The protrusion 123 of the electrode sheet 12 can be engaged with the corresponding stopper 1122 of the lower cover 112. The position-limiting structure 1122 of the lower cover 112 and the protrusion 123 of the electrode plate 12 can be designed differently according to actual requirements or different assembling manners. For example, the position-limiting structure 1122 may interfere with the end of the protrusion 123, as shown in fig. 4. Alternatively, the retention structure 1122 may grip the protrusion 123 or interfere with both sides of the protrusion 123, as shown in fig. 5. According to the structure, the electrode plate 12 can be prevented from sliding or falling off, so that the subsequent process is facilitated. For example, the electrode sheet 12 may be assembled with the lower cover 112, and then the assembled components are processed, such as cleaning, electroplating, chemical formula coating, etc., and finally assembled with the electronic device 13 and the upper cover 111.

Referring to fig. 6, in an embodiment, each of the electrode pads 12 and the electrical connection pads 14 has the same shape. During design, the electrodes are divided into a working electrode, a reference electrode or a relative electrode according to different functions. For example, the surface of the sensing end of a particular electrode pad (e.g., 12a, 12b) is coated with an appropriate sensing layer to serve as a working electrode, while the sensing ends of the

electrode pads

12c, 12d serve as a reference electrode and a counter electrode, respectively. It can be understood that the unified specification design of each electrode sheet 12 and the electrical connection sheet 14 can reduce the management and inventory cost, and is beneficial to design flexibility and achieve a small amount of diversified customized production. For example, in order to increase the amount of signals generated by the working electrode, a plurality of electrode pads functioning as the working electrode may be provided. Alternatively, different sensing layers may be coated on different working electrodes to measure different biological information.

In one embodiment, the signal processing component 132 can be a single electronic component or a plurality of electronic components, and can process the electronic signal generated by the sensing terminal and store or transmit the electronic signal to an external electronic device. For example, referring to fig. 7, the signal processing element 132 comprises a microprocessor 1321, a memory 1322 and a communication interface 1323. The microprocessor 1321 can process the electronic signals generated by the sensing terminal and store the processed signals in the storage unit 1322, or transmit the processed signals to an external electronic device, such as a computer, a mobile internet device, etc., through the communication interface 1323. In one embodiment, the communication interface 1323 can be a wireless communication module (e.g., a wireless local area network module, a bluetooth module) or a wired communication port (e.g., a USB port).

In summary, the biological information sensing patch of the present invention is connected to an electrode sheet by an electrical connection sheet, and is electrically connected to a substrate of an electronic device in a physical abutting manner, so that the number of parts and assembly processes of the biological information sensing patch of the present invention can be simplified, and mass automatic production can be achieved. Preferably, the electrical connection sheet and the electrode sheet are integrally formed and are components with the same shape, so that the management and inventory cost can be reduced, the design flexibility is facilitated, and a small amount of diversified customized production can be achieved.

The above-mentioned embodiments are merely illustrative of the technical spirit and features of the present invention, and the purpose thereof is to enable those skilled in the art to understand the content of the present invention and to implement the same, so that the scope of the present invention should not be limited thereto, i.e., all equivalent changes and modifications made in the spirit of the present invention should be covered by the scope of the present invention.

Claims

1. A bioinformation sensing patch, comprising:

a housing including an upper cover and a lower cover, wherein the upper cover and the lower cover define an accommodating space, and the lower cover includes a plurality of openings;

a plurality of electrode plates, which are arranged in the accommodating space and are electrically independent from each other, wherein each electrode plate comprises at least one sensing end, and the sensing end corresponds to the opening so as to expose the sensing end as a working electrode or a reference electrode;

an electronic device disposed in the accommodating space and comprising:

the substrate comprises a plurality of first conductive contacts and a plurality of second conductive contacts, and the first conductive contacts are electrically connected with the corresponding first conductive contacts; and

the signal processing element is arranged on the substrate and is electrically connected with the first conductive contact;

a plurality of electrical connection sheets, wherein a connection end of each electrical connection sheet is connected with the corresponding electrode sheet, and a contact end of each electrical connection sheet abuts against the corresponding second conductive contact of the substrate; and

and the power supply unit is electrically connected with the electronic device so as to provide power supply required by the operation of the electronic device.

2. The bioinformation sensing patch according to claim 1, wherein each of said electrode sheets has at least one folded edge, and said sensing end is disposed at the top end of said folded edge.

3. The biological information sensing patch according to claim 2, wherein the lower cover comprises at least one position-limiting structure disposed in the opening, the fold of the electrode sheet has at least one protrusion, and the protrusion is engaged with the corresponding position-limiting structure.

4. The bioinformation sensing patch according to claim 1, wherein the contact end of the electrical connection sheet abuts against the corresponding second conductive contact of the substrate with a deformation restoring force of the electrical connection sheet.

5. The bioinformation sensing patch according to claim 1, wherein the electrical connection sheet abuts against the second conductive contact at a bevel or an arc.

6. The bioinformation sensing patch according to claim 1, wherein at least one of said electrode pads is connected to a plurality of said electrical connection pads.

7. The bioinformation sensing patch according to claim 1, wherein said electrical connection tabs extend outwardly from said electrode pads.

8. The bioinformation sensing patch according to claim 1, wherein said contact end and said sensing end of said electrical connection pads are located on opposite sides of said electrode pads.

9. The bioinformation sensing patch according to claim 1, wherein the electrode pads and the electrical connection pads are integrally formed.

10. The bioinformation sensing patch according to claim 1, wherein each of said electrode pads and said electrical connection pads are identical in shape.

11. The bioinformation sensing patch according to claim 1, wherein said plurality of electrode pads comprise at least one of said reference electrode, at least one of said working electrode, and at least one counter electrode.

12. The bioinformatic sensing patch according to claim 1, wherein said plurality of electrode pads comprise at least one of said reference electrode and a plurality of said working electrodes.

13. The bioinformation sensing patch according to claim 1, wherein the plurality of electrode pads comprise at least one of the reference electrode and a plurality of the working electrodes, and surfaces of the plurality of working electrodes are coated with different sensing layers.

14. The bioinformation sensing patch according to claim 1, wherein said sensing end has the appearance of a pointed needle, a pointed bump or a flat surface.

15. The bioinformation sensing patch according to claim 1, wherein the material of the electrode sheet is stainless steel, nickel alloy, titanium or titanium alloy.

16. The bioinformation sensing patch according to claim 1, wherein said signal processing element comprises a memory unit.

17. The bioinformation sensing patch according to claim 1, wherein said signal processing element comprises a wireless communication module or a wired communication connection port.

18. The bioinformation sensing patch according to claim 1, wherein said lower cover comprises a semi-soft material having tackiness.

19. The bioinformation sensing patch according to claim 1, wherein said upper cover comprises a non-tacky semi-soft material.