CN113057732A - Laser ablation catheter - Google Patents
Laser ablation catheter Download PDFInfo
- Publication number
- CN113057732A CN113057732A CN202110317892.8A CN202110317892A CN113057732A CN 113057732 A CN113057732 A CN 113057732A CN 202110317892 A CN202110317892 A CN 202110317892A CN 113057732 A CN113057732 A CN 113057732A
- Authority
- CN
- China
- Prior art keywords
- catheter
- optical fiber
- type
- fiber bundle
- distal end
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/18—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves
- A61B18/20—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser
- A61B18/22—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser the beam being directed along or through a flexible conduit, e.g. an optical fibre; Couplings or hand-pieces therefor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00315—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for treatment of particular body parts
- A61B2018/00345—Vascular system
- A61B2018/00404—Blood vessels other than those in or around the heart
- A61B2018/0041—Removal of thrombosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/18—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves
- A61B18/20—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser
- A61B18/22—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser the beam being directed along or through a flexible conduit, e.g. an optical fibre; Couplings or hand-pieces therefor
- A61B2018/2205—Characteristics of fibres
- A61B2018/2211—Plurality of fibres
Abstract
The invention discloses a laser ablation catheter, which comprises a slender catheter and an optical fiber bundle, wherein the optical fiber bundle is arranged in the catheter, two ends of the catheter are divided into a catheter proximal end and a catheter distal end, the catheter proximal end is an input end of pulse laser, and the catheter distal end is an output end of the pulse laser; a side wall hole is arranged on the wall of the catheter at the far end of the catheter; the optical fiber bundles are divided into two types, the light beam emergent surface of the first type of optical fiber bundle is aligned with the distal end surface of the catheter, so that the light beams transmitted in the first type of optical fiber bundle are emitted in the forward direction; the far end face of the second type of optical fiber bundle is an inclined plane, and a reflecting film is plated on the inclined plane, so that the light beams transmitted in the second type of optical fiber bundle are reflected on the inclined plane, and are emitted out from the side face of the optical fiber and out of the catheter through the side wall hole on the catheter wall at the far end of the catheter. The light beams from the first type of fiber optic bundle can treat focal plaque located in front of the distal end of the catheter, and the side light beams from the second type of fiber optic bundle can be used for treating annular calcified lesions of the blood vessel.
Description
Technical Field
The invention belongs to the technical field of medical instruments, and particularly relates to a laser ablation catheter.
Background
Percutaneous Coronary Intervention (PCI) is a minimally invasive procedure, which is a treatment method for improving myocardial perfusion by dredging a narrow or even an occluded coronary artery lumen through a catheter technique. Conventional treatment means include angioplasty or stent implantation. However, coronary calcified lesions increase the difficulty of interventional treatment, increase the incidence of immediate surgical complications and major adverse cardiovascular events in early and late stages. The reason for this is that calcified lesions are high-resistance lesions and the balloon requires very high pressure (sometimes up to 10 to 15 atm, even 30 atm). Such pressure will generally increase the probability of rebound stenosis, dissection, perforation, rupture of the vessel significantly. Such surgical events are particularly severe in the case of eccentric calcified lesions, since the pressure of the balloon is exerted on the soft tissue without calcification.
Plaque ablation is a cardiac intervention assisted treatment technique, which includes rotational atherectomy, orbital atherectomy, laser ablation, etc. of plaque in the coronary artery. The main purpose is to achieve the effects of ablating calcified tissues and restoring lumen area through mechanical means or energy conversion. In recent years, Excimer Laser (Excimer Laser) intracoronary plaque ablation uses an ultraviolet light source, a catheter design, and a pulsed cold light source, which improves the effectiveness and safety of the surgery. The ultraviolet laser light source can be effectively absorbed by biological tissues and can provide enough energy to destroy intermolecular forces of surface tissues. At the same time, the absorption of light by the tissue causes a local temperature rise and causes photo-acoustic and photo-thermal ablation effects. These effects occur only in a thin layer on the surface of the biological tissue, with little effect on the surrounding tissue. After the catheter smoothly passes through the pathological changes, the balloon can be used for fully expanding and implanting the stent, and the revascularization can be completed.
Laser ablation can remove various lesions in the stenosed blood vessel, with the direction of laser light exiting the optical waveguide medium being substantially forward. In the ablation catheters used at present, the light path outlet of the light guide medium is at the tip of the catheter, so that only the tissue at the front end of the catheter can be ablated. This results in a laser ablated lumen area comparable to the cross-sectional area of the catheter. This is not ideal for the treatment of a wide range of calcified lesions, especially calcified rings. If one wants to treat lesions in a larger diameter range, one of the methods is to replace one larger size ablation catheter. The invention changes the light propagation direction of a part of the light guide, so that the light is emitted from the side surface of the guide tube. Lateral emergent light can act on the pathological tissue on the side surface of the catheter, particularly the calcification ring, can shatter or soften the calcification ring, can play a role similar to a spinous process saccule, and therefore preparation is made for expansion of the focus in the next step.
Disclosure of Invention
The invention aims to design a laser ablation catheter, which changes the light propagation direction of a part of optical fiber bundle so that the light beam is emitted from the side surface of the catheter.
The technical scheme of the invention is that the laser ablation catheter comprises a slender catheter and an optical fiber bundle, wherein the optical fiber bundle is arranged in the catheter, two ends of the catheter are divided into a catheter proximal end and a catheter distal end, the catheter proximal end is an input end of pulse laser, and the catheter distal end is an output end of the pulse laser; a side wall hole is arranged on the wall of the catheter at the far end of the catheter; the optical fiber bundles are divided into two types, the light beam emergent surface of the first type of optical fiber bundle is aligned with the distal end surface of the catheter, so that the light beams transmitted in the first type of optical fiber bundle are emitted in the forward direction; the far end face of the second type of optical fiber bundle is an inclined plane, and a reflecting film is plated on the inclined plane, so that the light beams transmitted in the second type of optical fiber bundle are reflected on the inclined plane, and are emitted out from the side face of the optical fiber and out of the catheter through the side wall hole on the catheter wall at the far end of the catheter.
An adjustable baffle is arranged in front of the input end of the pulse laser of the second type of optical fiber bundle.
The adjustable baffle is made of graphite material.
The number of side wall holes on the wall of the catheter at the far end of the catheter is 2-4, the second type of optical fiber bundle is divided into 2-4 bundles, and the second type of optical fiber bundle corresponds to the side wall holes on the wall of the catheter at the far end of the catheter.
The incident angle of the light beam transmitted in the second type of optical fiber bundle at the inclined plane is 20-70 degrees.
The preferred angle of incidence of the light beams transmitted in the second type of fiber optic bundle at the inclined plane is 50 ° to 60 °.
The distance from the light beam reflection inclined plane of the second type optical fiber bundle to the far end face of the catheter is 2 mm to 10 mm.
The preferred distance from the beam reflecting bevel of the second type of fiber optic bundle to the distal end face of the catheter is 3 mm to 5 mm.
The laser ablation catheter provided by the invention has the following advantages:
the invention provides a laser ablation catheter, wherein a side wall hole is formed in the wall of the catheter at the far end of the catheter; the optical fiber bundles in the catheter are divided into two types, the light beam emergent surface of the first type of optical fiber bundle is aligned with the distal end face of the catheter, and the direction of the light beam emergent from the light beam emergent surface of the first type of optical fiber bundle is basically parallel to the axial direction of the optical fiber, so that the light beam transmitted in the first type of optical fiber bundle is emergent in the forward direction; the far end face of the second type of optical fiber bundle is an inclined plane, and a reflecting film is plated on the inclined plane, so that the light beams transmitted in the second type of optical fiber bundle are reflected on the inclined plane, and are emitted out from the side face of the optical fiber and out of the catheter through the side wall hole on the catheter wall at the far end of the catheter.
The light beams emitted from the first type of optical fiber bundles are used for treating stenotic lesions of blood vessels, lesion plaques in front of the far end of the catheter can be well treated, a lumen with the size of the cross section of the catheter is formed in a narrow annular calcified area, and a necessary lumen area is provided for subsequent treatment. The lateral light beams emitted from the second type of optical fiber beams are used for treating annular calcified lesions of blood vessels, and can carry out laser ablation on lesion tissues around the wall of the catheter, particularly calcified rings, so as to shatter or soften the calcified rings, so that a lesion stenosis can be easily expanded subsequently, and the balloon expansion or stent placement is facilitated.
An adjustable baffle is arranged in front of the input end of the pulse laser of the second type of optical fiber bundle, and an operator can control the baffle to be opened or closed according to needs so as to control the output or non-output of the light beams in the second type of optical fiber bundle.
Drawings
Fig. 1 is a schematic cross-sectional view of a laser ablation catheter.
Fig. 2 is a schematic cross-sectional view of the distal end of a laser ablation catheter.
Fig. 3 is a perspective view of the distal end of a laser ablation catheter.
Fig. 4 is a schematic cross-sectional view of a catheter proximal joint of a laser ablation catheter.
The reference numbers illustrate:
100. catheter, 101, catheter proximal end, 102, catheter distal end, 103, catheter wall, 104, first type fiber bundle, 105, second type fiber bundle, 106, pulse laser, 107, guidewire lumen, 108, catheter distal end face, 109, side wall aperture, 110, bevel, 111, catheter proximal end fitting, 112, adjustable baffle, 113, beam exit face of first type fiber bundle, 114, transmission beam in second type fiber bundle, 115, exit beam in second type fiber bundle, 116, guidewire, 117, visualization ring, 118, rectangular fixture, positioning device,
Detailed Description
In order to make the implementation objects, technical solutions and advantages of the present invention clearer, the technical solutions in the embodiments of the present invention will be described in more detail below with reference to the accompanying drawings in the embodiments of the present invention. It should be emphasized that the following description is merely exemplary in nature and is not intended to limit the scope of the invention or its application.
Examples
A laser ablation catheter of the type described in this example is shown in figures 1 to 4.
As shown in fig. 1, the laser ablation catheter according to the embodiment includes an elongated catheter 100 and a fiber bundle, the fiber bundle is installed in the catheter 100, two ends of the catheter 100 are divided into a catheter proximal end 101 and a catheter distal end 102, the catheter proximal end 101 is an input end of a pulse laser, and the catheter distal end 102 is an output end of the pulse laser; a side wall hole 109 is arranged on the catheter wall 103 of the catheter distal end 102; the optical fiber bundles are divided into two types, the light beam emergent surface 113 of the first type optical fiber bundle 104 is aligned with the far-end face 108 of the catheter, the direction of the light beam emergent from the light beam emergent surface 113 of the first type optical fiber bundle 104 is basically parallel to the axial direction of the optical fiber, and the light beam transmitted in the first type optical fiber bundle 104 is emergent in the forward direction; the distal end face of the second type optical fiber bundle 105 is an inclined surface 110, and a reflective film is coated on the inclined surface 110, so that the light beam 114 transmitted in the second type optical fiber bundle 105 is reflected on the inclined surface 110, and the light beam 115 is emitted from the side surface of the optical fiber and is emitted out of the catheter through the side wall hole 109 on the catheter wall 103 of the distal end 102 of the catheter.
The catheter 100 is provided with a guide wire lumen 107, one end of the guide wire lumen 107 being open at the catheter distal end face 108, the other end of the guide wire lumen 107 being open at the catheter wall 103. The fiber bundle at the proximal end 101 of the catheter is connected with a pulse laser 106 through a proximal catheter connector 111, and the pulse laser output by the pulse laser 106 is transmitted through a first type fiber bundle 104 and a second type fiber bundle 105, and is emitted in the forward direction at the distal end face 108 of the catheter and is emitted in the side wall hole 109 on the catheter wall 103 at the distal end 102 of the catheter. The inclined plane 110 of the beam exit surface of the second type optical fiber bundle 105 can be formed by grinding, and a dielectric film can be coated on the ground inclined plane 110 by ion beam sputtering deposition to form a reflective film surface, so that the beam is reflected on the inclined plane 110 and exits from the side surface of the optical fiber.
As shown in fig. 2, this is a schematic cross-sectional view of the distal end 102 of the catheter and indicates the direction of propagation of the light beam in dashed lines. The optical fiber bundle in the invention can be formed by slender optical fibers with circular cross sections, and also can be formed by slender optical fibers with other cross section shapes. In this embodiment, a fiber bundle is composed of slender optical fibers having a circular cross section. The optical fiber bundle is composed of at least two optical fibers so as to divide the optical fiber bundle into two types of optical fiber bundles for emitting a forward light beam and a side light beam. In this embodiment, 3 side wall holes 109 are adopted, the optical fiber bundle is composed of at least 4 optical fibers, one optical fiber emits forward light beams, and 3 optical fibers emit lateral light beams, and the actual number of the optical fibers can be determined by actual needs. As can be seen in fig. 2, the light beam exit face 113 of the first-type fiber bundle 104 is aligned with the catheter distal end face 108, so that the light beams transmitted in the first-type fiber bundle 104 exit in the forward direction. The light beam 114 transmitted in the bundle 105 of the second type is reflected at the inclined surface 110, so that the outgoing light beam 115 in the bundle of the second type exits from the side of the optical fiber and exits the catheter laterally through the side wall hole 109 in the catheter wall 103 at the distal end 102 of the catheter. The angle of incidence of the light beam 114 transmitted in the second type 105 on the inclined surface 110 is between 20 ° and 70 °, preferably between 50 ° and 60 °, which ensures that the outgoing light beam 115 is deflected by 40 ° to 140 °, or preferably by 100 ° to 120 °, in this embodiment 55 °, and the outgoing light beam 115 is deflected by 110 ° with respect to the fiber axis. The distance from the beam exit ramp 110 of the second type of fiber optic bundle 105 to the distal end face 108 of the catheter is between 2 mm and 10 mm, preferably between 3 mm and 5 mm. In this embodiment, the distance from the light beam exit bevel 110 of the second type optical fiber bundle 105 to the distal end face 108 of the catheter is 4 mm.
This is a perspective view of the distal end 102 of the catheter, as shown in fig. 3. A guidewire 116 is threaded into the guidewire lumen 107 of the catheter 100, and the guidewire 116 guides the catheter 100 along the guidewire 116 into the blood vessel and proximate the lesion area. The light beam exit face 113 of the first-type bundle 104 is aligned with the catheter distal end face 108, and the light beam transmitted in the first-type bundle 104 exits forward. The light beams transmitted in the second type of fiber optic bundle 105 (not labeled in fig. 3) exit the catheter laterally from side wall apertures 109 in the catheter wall 103 at the distal end 102 of the catheter. Since the second-type fiber bundle 105 does not reach the catheter distal end face 108, the beam exit face 113 of the first-type fiber bundle 104 on the catheter distal end face 108 cannot completely cover the catheter distal end face 108. The catheter distal end 102 is also fitted with a visualization ring 117 so that the catheter distal end 102 is visible in angiographic imaging.
This is a schematic cross-sectional view of the catheter proximal hub 111, as shown in fig. 4. The first type 104 and second type 105 optical fiber bundles are bundled at the proximal end 101 of the catheter. The bundled fiber bundle arrangement should match the shape of the exit aperture of the pulsed laser 106. In the present exemplary embodiment, the exit aperture of the pulse laser 106 may be rectangular. The first type 104 and second type 105 optical fiber bundles are thus arranged substantially in a rectangle and are fixed in shape and position by a rectangular fixing device 118.
In the present exemplary embodiment, the present invention is illustrated by representing the second type of fiber bundle 105 with three fibers. The second type of fiber optic bundle 105 is arranged at a lateral position. The selective switching of the delivery of the side-emitting pulsed laser light by the second-type fiber optic bundle 105 is accomplished by whether the optical input of the second-type fiber optic bundle 105 at the proximal end 101 of the catheter is blocked. When the catheter proximal end 101 input light of the second type fiber optic bundle 105 is blocked, the second type fiber optic bundle 105 will not emit pulsed laser light. The shield may be a mechanical device or a photoelectric effect device. In the exemplary embodiment, this shielding is illustrated by a rotatable adjustable bezel 112. An adjustable baffle 112 is installed in front of the input end of the pulse laser of the second type optical fiber bundle 105. When the adjustable stop 112 is in the current position of FIG. 4, it does not block the second type of fiber optic bundle 105. When the adjustable stop 112 is rotated to the rectangular dashed line position, it can block the second type fiber bundle 105 without affecting the first type fiber bundle 104. The adjustable stop 112 may be made of a light absorbing material such as graphite to attenuate reflected light, reduce the energy of the light reflected back to the pulsed laser 106, and protect the pulsed laser 106.
A laser ablation catheter of the present embodiment is used in conjunction with a vascular guidewire 116 during a procedure for treating a diseased plaque in a blood vessel. The tip of the guidewire 116 at the focal region to be treated is inserted into the guidewire lumen 107 from the catheter distal end face 108 and the catheter 100 is advanced over the guidewire 116 to the vicinity of the lesion. When a stenosis is encountered and the catheter 100 cannot pass through, the pulsed laser 106 may be turned on to perform laser ablation on the lesion. The light beam emitted from the first type optical fiber bundle 104 is used for treating the stenosis of the blood vessel, so that lesion plaque positioned in front of the distal end 102 of the catheter can be well treated, a lumen with the size of the cross section of the catheter 100 is opened in the annular calcified area of the stenosis, and a necessary lumen area is provided for subsequent treatment. The side light beam 115 emitted from the second type optical fiber bundle 105 is used for treating annular calcified lesion of blood vessel, and can perform laser ablation on lesion tissue around the catheter wall 103, especially calcified ring, according to requirements, so as to crack or soften the calcified ring, so that the lesion stenosis can be easily expanded subsequently, and the balloon expansion or stent placement is facilitated.
The pulsed laser 106 used for laser ablation has a wavelength between 300 nanometers and 420 nanometers. Optionally, the pulsed laser is a Nd: YAG third harmonic laser with a wavelength of 355 nm. When the wavelength is used, the energy flux of each pulse emitted by the optical fiber bundle is at least 50mJ/mm2I.e. a sufficient amount of light energy per unit area is required. The pulse frequency emitted by the optical fiber bundle is at least 10Hz, and preferably between 25Hz and 40 Hz. Optionally, the pulsed laser 106 is an excimer laser with a wavelength of 308 nm. When the wavelength is used, the energy flux of each pulse emitted by the optical fiber bundle is at least 30mJ/mm2. The pulse frequency emitted by the optical fiber bundle is at least 10Hz, and preferably between 25Hz and 40 Hz.
Finally, it should be pointed out that: the above examples are only for illustrating the technical solutions of the present invention, and are not limited thereto. Although the present invention has been described in detail with reference to the foregoing embodiments, it will be understood by those of ordinary skill in the art that: the technical solutions described in the foregoing embodiments may still be modified, or some technical features may be equivalently replaced; and such modifications or substitutions do not depart from the spirit and scope of the corresponding technical solutions of the embodiments of the present invention.
Claims (8)
1. A laser ablation catheter comprises a slender catheter and an optical fiber bundle, wherein the optical fiber bundle is arranged in the catheter, two ends of the catheter are divided into a catheter proximal end and a catheter distal end, the catheter proximal end is an input end of pulse laser, and the catheter distal end is an output end of the pulse laser; the method is characterized in that: a side wall hole is arranged on the wall of the catheter at the far end of the catheter; the optical fiber bundles are divided into two types, the light beam emergent surface of the first type of optical fiber bundle is aligned with the distal end surface of the catheter, so that the light beams transmitted in the first type of optical fiber bundle are emitted in the forward direction; the far end face of the second type of optical fiber bundle is an inclined plane, and a reflecting film is plated on the inclined plane, so that the light beams transmitted in the second type of optical fiber bundle are reflected on the inclined plane, and are emitted out from the side face of the optical fiber and out of the catheter through the side wall hole on the catheter wall at the far end of the catheter.
2. A laser ablation catheter as in claim 1, wherein: an adjustable baffle is arranged in front of the input end of the pulse laser of the second type of optical fiber bundle.
3. A laser ablation catheter as claimed in claim 2, wherein: the adjustable baffle is made of graphite material.
4. A laser ablation catheter as in claim 1, wherein: the number of side wall holes on the wall of the catheter at the far end of the catheter is 2-4, the second type of optical fiber bundle is divided into 2-4 bundles, and the second type of optical fiber bundle corresponds to the side wall holes on the wall of the catheter at the far end of the catheter.
5. A laser ablation catheter as in claim 1, wherein: the incident angle of the light beam transmitted in the second type of optical fiber bundle at the inclined plane is 20-70 degrees.
6. A laser ablation catheter as in claim 5, wherein: the preferred angle of incidence of the light beams transmitted in the second type of fiber optic bundle at the inclined plane is 50 ° to 60 °.
7. A laser ablation catheter as in claim 1, wherein: the distance from the light beam reflection inclined plane of the second type optical fiber bundle to the far end face of the catheter is 2 mm to 10 mm.
8. A laser ablation catheter as in claim 7, wherein: the preferred distance from the beam reflecting bevel of the second type of fiber optic bundle to the distal end face of the catheter is 3 mm to 5 mm.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202110317892.8A CN113057732A (en) | 2021-03-25 | 2021-03-25 | Laser ablation catheter |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202110317892.8A CN113057732A (en) | 2021-03-25 | 2021-03-25 | Laser ablation catheter |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN113057732A true CN113057732A (en) | 2021-07-02 |
Family
ID=76561936
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202110317892.8A Pending CN113057732A (en) | 2021-03-25 | 2021-03-25 | Laser ablation catheter |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN113057732A (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114431955A (en) * | 2022-02-14 | 2022-05-06 | 清华大学 | Ultrafast laser galvanometer scanning coupling method |
| CN114587575A (en) * | 2022-03-11 | 2022-06-07 | 文皓(武汉)医疗科技有限责任公司 | Intravascular plaque pitting device with adjustable double-path laser power |
| CN115337102A (en) * | 2022-08-25 | 2022-11-15 | 文皓(武汉)科技有限责任公司 | Double-light-path laser energy adjustable laser guide pipe in single-beam optical fiber |
Citations (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5109859A (en) * | 1989-10-04 | 1992-05-05 | Beth Israel Hospital Association | Ultrasound guided laser angioplasty |
| US5242437A (en) * | 1988-06-10 | 1993-09-07 | Trimedyne Laser Systems, Inc. | Medical device applying localized high intensity light and heat, particularly for destruction of the endometrium |
| US5891133A (en) * | 1996-03-29 | 1999-04-06 | Eclipse Surgical Technologies, Inc. | Apparatus for laser-assisted intra-coronary transmyocardial revascularization and other applications |
| US20100081873A1 (en) * | 2008-09-30 | 2010-04-01 | AiHeart Medical Technologies, Inc. | Systems and methods for optical viewing and therapeutic intervention in blood vessels |
| CN103149649A (en) * | 2013-03-29 | 2013-06-12 | 曹晨 | Optical fiber controller |
| CN103487887A (en) * | 2013-10-10 | 2014-01-01 | 核工业理化工程研究院 | Device for integrating and transmitting different-wavelength multi-path lasers and use method thereof |
| CN204073133U (en) * | 2014-07-16 | 2015-01-07 | 中国人民解放军军事医学科学院放射与辐射医学研究所 | A kind of novel green Lasar prostate therapy apparatus |
| US20190125447A1 (en) * | 2016-05-05 | 2019-05-02 | Eximo Medical Ltd | Apparatus and methods for resecting and/or ablating an undesired tissue |
-
2021
- 2021-03-25 CN CN202110317892.8A patent/CN113057732A/en active Pending
Patent Citations (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5242437A (en) * | 1988-06-10 | 1993-09-07 | Trimedyne Laser Systems, Inc. | Medical device applying localized high intensity light and heat, particularly for destruction of the endometrium |
| US5109859A (en) * | 1989-10-04 | 1992-05-05 | Beth Israel Hospital Association | Ultrasound guided laser angioplasty |
| US5891133A (en) * | 1996-03-29 | 1999-04-06 | Eclipse Surgical Technologies, Inc. | Apparatus for laser-assisted intra-coronary transmyocardial revascularization and other applications |
| US20100081873A1 (en) * | 2008-09-30 | 2010-04-01 | AiHeart Medical Technologies, Inc. | Systems and methods for optical viewing and therapeutic intervention in blood vessels |
| CN103149649A (en) * | 2013-03-29 | 2013-06-12 | 曹晨 | Optical fiber controller |
| CN103487887A (en) * | 2013-10-10 | 2014-01-01 | 核工业理化工程研究院 | Device for integrating and transmitting different-wavelength multi-path lasers and use method thereof |
| CN204073133U (en) * | 2014-07-16 | 2015-01-07 | 中国人民解放军军事医学科学院放射与辐射医学研究所 | A kind of novel green Lasar prostate therapy apparatus |
| US20190125447A1 (en) * | 2016-05-05 | 2019-05-02 | Eximo Medical Ltd | Apparatus and methods for resecting and/or ablating an undesired tissue |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114431955A (en) * | 2022-02-14 | 2022-05-06 | 清华大学 | Ultrafast laser galvanometer scanning coupling method |
| CN114587575A (en) * | 2022-03-11 | 2022-06-07 | 文皓(武汉)医疗科技有限责任公司 | Intravascular plaque pitting device with adjustable double-path laser power |
| CN115337102A (en) * | 2022-08-25 | 2022-11-15 | 文皓(武汉)科技有限责任公司 | Double-light-path laser energy adjustable laser guide pipe in single-beam optical fiber |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US11090117B2 (en) | System for tissue ablation using pulsed laser | |
| CN113057732A (en) | Laser ablation catheter | |
| US5109859A (en) | Ultrasound guided laser angioplasty | |
| US4854315A (en) | Laser catheter | |
| US20130023865A1 (en) | Imaging and Eccentric Atherosclerotic Material Laser Remodeling and/or Ablation Catheter | |
| CN113180822B (en) | Catheter integrating laser ablation and vascular shock wave forming | |
| EP0225913A1 (en) | Laser angioplasty | |
| CN113040903A (en) | Laser ablation system | |
| CN113017827B (en) | Catheter system integrating ultrasonic imaging and laser ablation | |
| CN113040901B (en) | Laser ablation catheter with additional shock wave ball bag | |
| CN113040902B (en) | Laser ablation catheter | |
| Anderson et al. | Steerable fiberoptic catheter delivery of laser energy in atherosclerotic rabbits | |
| WO1990006087A1 (en) | Single axis/angled beam laser catheter | |
| WO1990005562A1 (en) | Angioplasty catheter with off-axis angled beam delivery fiber | |
| Bowker | Laser-tissue interaction and arterial perforation thresholds in laser angioplasty | |
| BITTL et al. | Wire‐Guided Excimer Laser Coronary Angioplasty: Instrument Selection, Lesion Characterization, and Operator Technique | |
| Ollivier et al. | Intraoperative coronary artery endarterectomy with excimer laser | |
| Chen et al. | Laser Atherectomy | |
| GESCHWIND | The Current Status of Laser Angioplasty | |
| Bussiere et al. | Intraoperative XeCl Excimer Laser Coronary Artery Endarterectomy: Clinical Experience. | |
| Eichenauer et al. | New application system for the holmium laser resection of the prostate | |
| Barbieri et al. | Three years experience with thermal and excimer lasers in the treatment of peripheral artery disease | |
| Fracasso et al. | UV Laser Angioplasty: Clinical Aspects |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| WD01 | Invention patent application deemed withdrawn after publication | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20210702 |