CN113041389A - Medical dressing of antibiotic hydrophilic polyurethane foam - Google Patents
Medical dressing of antibiotic hydrophilic polyurethane foam Download PDFInfo
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- CN113041389A CN113041389A CN202110490860.8A CN202110490860A CN113041389A CN 113041389 A CN113041389 A CN 113041389A CN 202110490860 A CN202110490860 A CN 202110490860A CN 113041389 A CN113041389 A CN 113041389A
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- A—HUMAN NECESSITIES
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- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/42—Use of materials characterised by their function or physical properties
- A61L15/425—Porous materials, e.g. foams or sponges
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/18—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing inorganic materials
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/20—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing organic materials
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/22—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
- A61L15/26—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds; Derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/40—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing ingredients of undetermined constitution or reaction products thereof, e.g. plant or animal extracts
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/42—Use of materials characterised by their function or physical properties
- A61L15/44—Medicaments
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/42—Use of materials characterised by their function or physical properties
- A61L15/46—Deodorants or malodour counteractants, e.g. to inhibit the formation of ammonia or bacteria
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
- A61L2300/30—Compounds of undetermined constitution extracted from natural sources, e.g. Aloe Vera
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- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/404—Biocides, antimicrobial agents, antiseptic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/41—Anti-inflammatory agents, e.g. NSAIDs
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Abstract
The invention discloses an antibacterial hydrophilic polyurethane foam medical dressing, and relates to the technical field of medical dressings. The antibacterial hydrophilic polyurethane foam medical dressing comprises the following formula raw materials in parts by weight: non-woven adhesive fabric, deionized water, monovalent silver ion solution, glycerol, carbomer, triethanolamine, cationic polymer antibacterial agent, hydrophilic fiber, foam stabilizer, surfactant, silicone oil, polyurethane part and medical auxiliary material. According to the antibacterial hydrophilic polyurethane foam medical dressing, hydrophilic fibers and monovalent silver ion solution are added into raw materials, the hydrophilic fiber dressing is composed of natural fibers, can be tightly attached to a wound, is strong in absorption capacity, can absorb exudate of the wound, forms a layer of gel, can keep the surface of the wound moist, is beneficial to wound healing, helps to remove necrotic tissue of the wound without damaging new tissues, and avoids secondary injury to the wound.
Description
Technical Field
The invention relates to the technical field of medical dressings, in particular to an antibacterial hydrophilic polyurethane foam medical dressing.
Background
Essential article during medical treatment during dressing can all use dressing to wrap for patient's wound when handling patient's wound usually, but most dressing on the market all adopt the gauze to make at present, such dressing can only reach and carry out the effect of wrapping up for patient's wound to traditional dressing has not satisfied people daily demand, for example, the patent that publication is CN210408777U, although can accelerate the healing of wound, but do not possess the function of antibiotic disinfection, lead to the wound secondary infection to appear when probably using, thereby influence patient's health.
Disclosure of Invention
The invention aims to provide an antibacterial hydrophilic polyurethane foam medical dressing to solve the problems in the background technology.
In order to achieve the purpose, the invention provides the following technical scheme: an antibacterial hydrophilic polyurethane foam medical dressing comprises the following formula raw materials in parts by weight: 200-250 parts of non-setting adhesive non-woven fabric, 110-130 parts of deionized water, 0.1-0.3 part of monovalent silver ion solution, 2-3 parts of glycerol, 0.2-0.4 part of carbomer, 0.5-1.5 parts of triethanolamine, 2-6 parts of cationic polymer antibacterial agent, 1-3 parts of hydrophilic fiber, 1.5-2.5 parts of foam stabilizer, 2-4 parts of surfactant, 0.8-1.3 parts of silicone oil, 0.5-0.8 part of polyurethane and 20-50 parts of medical auxiliary material.
Preferably, the medical auxiliary materials comprise the following raw materials in parts by weight: 5-7 parts of overlord, 6-8 parts of white washington, 8-12 parts of thyme, 4-6 parts of moisturizing factor, 2-4 parts of cacumen biotae, 1-3 parts of tea tree oil, 2-4 parts of ivy and 2-6 parts of orange flower.
Preferably, the surfactant is at least one of L-64, P188, PEG-400, PEG-600, PEG-800, PEG4000 and PEG6000, and the surfactant is required to be sealed and stored in a refrigerating chamber with the temperature of 10-15 ℃.
Preferably, the cationic polymeric antimicrobial agent is one of polyhexamethylene guanidine hydrochloride, polyhexamethylene biguanide hydrochloride and polyhexamethylene guanidine phosphate.
An antibacterial hydrophilic polyurethane foam medical dressing, the preparation method comprises the following steps:
s1, crushing the material: washing white washings, thyme, cacumen biotae, tea tree oil, ivy and orange flowers in medical accessories with clean clear water, draining water in the medical accessories by using a fan after washing, spraying disinfection solution such as alcohol for disinfection treatment, sealing after disinfection for 20-30 minutes, respectively putting the accessories into a wall breaking machine after the medical accessories are disinfected, and adding a proper amount of deionized water for crushing;
s2, filtering, collecting and mixing materials: collecting liquid obtained after crushing Baishan mountain, thyme, cacumen biotae, tea tree oil, ivy and orange flowers, filtering the liquid by using fine gauze after collection, filtering and taking out crushed impurities, leaving the liquid, sequentially putting the liquid into a mixing stirrer, starting the stirrer to mix the solution, wherein the mixing time is 5-8 minutes, taking out the mixed solution after mixing, adding corresponding components of overlord and moisturizing factors, filtering the mixed solution by using fine gauze again to ensure that the impurities in the solution are less than 0.1%, taking out the solution, bottling and sealing for later use;
s3, preparing auxiliary materials: taking out deionized water, monovalent silver ion solution, glycerol, carbomer, triethanolamine, cationic polymer antibacterial agent, hydrophilic fiber, foam stabilizer, surfactant, silicone oil and polyurethane with corresponding fractions, sequentially putting the deionized water, monovalent silver ion solution, glycerol, carbomer, triethanolamine, cationic polymer antibacterial agent, hydrophilic fiber, foam stabilizer, surfactant, silicone oil and polyurethane into a mixing and stirring device for stirring for 20-30 minutes, mixing all dressing raw materials, standing for 30 minutes after mixing, adding the solution mixed with medical auxiliary materials into the auxiliary material raw materials for secondary mixing and stirring, wherein the stirring time is 10-15 minutes, and taking out all the materials for later use after fully mixing;
s4, sterilizing materials: putting the mixed raw materials into a pasteurization machine, sterilizing for 10-12 minutes, bottling after sterilization, and putting into a refrigerator at 5-10 ℃ for preservation and cooling;
s5, preparing the dressing: cutting the non-setting adhesive fabric into the same size, taking out the sterilized and cooled solution, uniformly coating the solution on the non-setting adhesive fabric to ensure that the ratio of the non-setting adhesive fabric to the auxiliary material is 2:1, and sealing.
Preferably, the medical auxiliary material in the step S1 is washed at least twice, the rotating speed of the wall breaking machine is 350-.
Preferably, the rotation speed of the S2 mixing mechanical rotation is 260-.
Preferably, the processing environments of the S1, S2, S3, S4 and S5 are carried out in a dust-free workshop, dust-free and sterile treatment is carried out in the workshop, and workers need to change clothes, wash hands and sterilize the whole body when working.
Compared with the prior art, the invention has the beneficial effects that:
(1) this medical dressing of antibiotic hydrophilic polyurethane foam, hydrophilic fibre and monovalent silver ion solution have been added in raw materials inside, hydrophilic fibre dressing comprises natural fibre on the one hand, can be closely obeyed on the wound, the absorbing capacity is strong, can absorb the exudate of wound, form one deck gel, this gel can make the wound surface keep moist, help wound healing, help to clear away the wound necrotic tissue and can not harm the new-born tissue, avoid wound secondary damage, on the other hand monovalent silver ion solution has certain antibiotic effect, make its in-process that uses not only can play bactericidal effect to the wound, simultaneously can also prevent breeding of bacterium constantly at subsequent in-process, thereby protection wound that can be fine, prevent that the wound from appearing the infection.
(2) This medical dressing of antibiotic hydrophilic polyurethane foam, the cost that contains a large amount of Chinese herbal medicines in the medical auxiliary material, on the one hand these Chinese herbal medicines can play and restrain fungal infection, anti-inflammation and anti-inflammation, antibiotic and detoxify, can clear away deposited toxin, thereby can better protect the wound when using the dressing, prevent that secondary infection from appearing in the in-process wound that uses, influence user's health, on the other hand can also converge pore moisturizing, anti-allergy, but remove unnecessary grease, whiten moisturizing, make the skin fresh and cool not greasy contain pectin and phospholipid material, not only so can also protect the skin around the wound when using dressing treatment wound, thereby can improve medical dressing's result of use.
(3) This medical dressing of antibiotic hydrophilic polyurethane foam can guarantee that the auxiliary material lasts and processes in clean and sanitary workshop when making the dressing to can guarantee to produce the dressing that has high quality, adopt the mode of filtration and stirring many times during simultaneous processing, so not only can make the dressing have more exquisite effect when using, can also guarantee simultaneously that every piece of dressing inside contained raw materials is all the same basically, thereby can guarantee that the dressing after the production all reaches qualified quality.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
The first embodiment is as follows: an antibacterial hydrophilic polyurethane foam medical dressing comprises the following formula raw materials in parts by weight: 200 parts of non-setting adhesive non-woven fabric, 110 parts of deionized water, 0.1 part of monovalent silver ion solution, 2 parts of glycerol, 0.2 part of carbomer, 0.5 part of triethanolamine, 2 parts of cationic polymer antibacterial agent, 1 part of hydrophilic fiber, 1.5 parts of foam stabilizer, 2 parts of surfactant, 0.8 part of silicone oil, 0.5 part of polyurethane and 20 parts of medical auxiliary material, wherein the medical auxiliary material comprises the following raw materials in parts by weight: 5 parts of overlord essence, 6 parts of white washings, 8 parts of thyme, 4 parts of moisturizing factor, 2 parts of cacumen biotae, 1 part of tea tree oil, 2 parts of ivy and 2 parts of orange flower, wherein the surfactant is at least one of L-64, P188, PEG-400, PEG-600, PEG-800, PEG4000 and PEG6000, the surfactant is required to be sealed in a refrigerating chamber at the temperature of 10-15 ℃ for storage, and the cationic polymer antibacterial agent is one of polyhexamethylene guanidine hydrochloride, polyhexamethylene biguanide hydrochloride and polyhexamethylene guanidine phosphate.
An antibacterial hydrophilic polyurethane foam medical dressing is prepared by the following steps:
s1, crushing the material: washing white washings, thyme, cacumen biotae, tea tree oil, ivy and orange flowers in medical auxiliary materials with clean clear water, draining water in the medical auxiliary materials by using a fan after washing, spraying disinfection solution such as alcohol to disinfect the medical auxiliary materials, sealing the medical auxiliary materials after disinfection, wherein the sealing time is 20 minutes, after the medical auxiliary materials are disinfected, respectively putting the medical auxiliary materials into a wall breaking machine, adding a proper amount of deionized water to break the medical auxiliary materials, washing the medical auxiliary materials in S1 at least twice, rotating the wall breaking machine at 350r/min, and air-drying the fan for 10 minutes to ensure that the interior of the medical auxiliary materials has 30% of water content, the sprayed alcohol is required to be more than or equal to 75%, and turning the medical auxiliary materials to enable the medical auxiliary materials to be sprayed to the alcohol at every angle; s2, filtering, collecting and mixing materials: collecting liquid obtained after crushing the white washings, thyme, cacumen biotae, tea tree oil, ivy and orange flowers, filtering the liquid by using fine gauze after collection, filtering and taking out crushed impurities to leave the liquid, sequentially putting the liquid into a mixing stirrer, starting the stirrer to mix the solution, wherein the mixing time is 5 minutes, taking out the liquid after mixing, adding corresponding components of overlord and moisturizing factors, filtering the mixed solution again by using fine gauze to ensure that the content of the impurities in the solution is less than 0.1%, taking out the solution after bottling and sealing for later use, wherein the rotating speed of a S2 mixing machine is 260r/min, the specification of the gauze used during the first filtration is 100 meshes, and the specification of the gauze used during the second filtration is 300 meshes; s3, preparing auxiliary materials: taking out deionized water, monovalent silver ion solution, glycerol, carbomer, triethanolamine, cationic polymer antibacterial agent, hydrophilic fiber, foam stabilizer, surfactant, silicone oil and polyurethane with corresponding fractions, sequentially putting the deionized water, the monovalent silver ion solution, the glycerol, the carbomer, the triethanolamine, the cationic polymer antibacterial agent, the hydrophilic fiber, the foam stabilizer, the surfactant, the silicone oil and the polyurethane into a mixing and stirring device to be stirred for 20 minutes, mixing all dressing raw materials, standing the mixture for 30 minutes, adding the solution mixed with the medical auxiliary materials into the auxiliary material raw materials to be mixed and stirred for the second time, stirring the mixture for 10 minutes, and taking out the mixture for later use after all; s4, sterilizing materials: putting the mixed raw materials into a pasteurization machine, sterilizing for 10 minutes, bottling after sterilization, and putting into a refrigeration box with the temperature of 5 ℃ for preservation and cooling after bottling; s5, preparing the dressing: the method comprises the steps of cutting the non-setting adhesive fabric into the same size, taking out the sterilized and cooled solution, uniformly coating the solution on the non-setting adhesive fabric, enabling the ratio of the non-setting adhesive fabric to auxiliary materials to be 2:1, sealing the non-setting adhesive fabric and the auxiliary materials, wherein the processing environment of S1, S2, S3, S4 and S5 needs to be carried out in a dust-free workshop, dust-free and sterile treatment needs to be carried out in the workshop, and workers need to change clothes, wash hands, sterilize and disinfect the whole body when working.
Example two: an antibacterial hydrophilic polyurethane foam medical dressing comprises the following formula raw materials in parts by weight: 225 parts of non-setting adhesive non-woven fabric, 120 parts of deionized water, 0.2 part of monovalent silver ion solution, 2.5 parts of glycerol, 0.3 part of carbomer, 1 part of triethanolamine, 4 parts of cationic polymer antibacterial agent, 2 parts of hydrophilic fiber, 2 parts of foam stabilizer, 3 parts of surfactant, 1 part of silicone oil, 0.6 part of polyurethane and 35 parts of medical auxiliary material, wherein the medical auxiliary material comprises the following raw materials in parts by weight: 6 parts of overlord essence, 7 parts of white washington, 10 parts of thyme, 5 parts of moisturizing factor, 3 parts of cacumen biotae, 2 parts of tea tree oil, 3 parts of ivy and 4 parts of orange flower, wherein the surfactant is at least one of L-64, P188, PEG-400, PEG-600, PEG-800, PEG4000 and PEG6000, the surfactant is required to be sealed in a refrigerating chamber at the temperature of 10-15 ℃ for storage, and the cationic polymer antibacterial agent is one of polyhexamethylene guanidine hydrochloride, polyhexamethylene biguanide hydrochloride and polyhexamethylene guanidine phosphate.
An antibacterial hydrophilic polyurethane foam medical dressing is prepared by the following steps:
s1, crushing the material: washing white washings, thyme, cacumen biotae, tea tree oil, ivy and orange flowers in medical auxiliary materials with clean clear water, draining water in the medical auxiliary materials by using a fan after washing, spraying disinfection solution such as alcohol to disinfect the medical auxiliary materials, sealing the medical auxiliary materials after disinfection, wherein the sealing time is 25 minutes, after the medical auxiliary materials are disinfected, respectively putting the auxiliary materials into a wall breaking machine, adding a proper amount of deionized water to break the auxiliary materials, washing the medical auxiliary materials in S1 at least for more than two times, rotating the wall breaking machine at a speed of 400r/min, and air-drying the fan for 12 minutes to ensure that the interior of the medical auxiliary materials has a water content of 33 percent, the sprayed alcohol needs to be more than or equal to 75 percent, and the medical auxiliary materials need to be turned over during spraying to ensure that the alcohol can be sprayed at every angle; s2, filtering, collecting and mixing materials: collecting liquid obtained after crushing the white washings, thyme, cacumen biotae, tea tree oil, ivy and orange flowers, filtering the liquid by using fine gauze after collection, filtering and taking out crushed impurities to leave the liquid, sequentially putting the liquid into a mixing stirrer, starting the stirrer to mix the solution, wherein the mixing time is 7 minutes, taking out the liquid after mixing, adding corresponding components of overlord and moisturizing factors, filtering the mixed solution again by using fine gauze to ensure that the content of the impurities in the solution is less than 0.1%, taking out the solution after bottling and sealing for later use, wherein the rotating speed of a S2 mixing machine is 270r/min, the specification of the gauze used during the first filtration is 150 meshes, and the specification of the gauze used during the second filtration is 350 meshes; s3, preparing auxiliary materials: taking out deionized water, monovalent silver ion solution, glycerol, carbomer, triethanolamine, cationic polymer antibacterial agent, hydrophilic fiber, foam stabilizer, surfactant, silicone oil and polyurethane with corresponding fractions, sequentially putting the deionized water, the monovalent silver ion solution, the glycerol, the carbomer, the triethanolamine, the cationic polymer antibacterial agent, the hydrophilic fiber, the foam stabilizer, the surfactant, the silicone oil and the polyurethane into a mixing and stirring device to be stirred for 25 minutes, mixing all dressing raw materials, standing the mixture for 30 minutes, adding the solution mixed with the medical auxiliary materials into the auxiliary material raw materials to be mixed and stirred for the second time, stirring the mixture for 13 minutes, and taking out the mixture for later use after all; s4, sterilizing materials: putting the mixed raw materials into a pasteurization machine, sterilizing for 11 minutes, bottling after sterilization, and putting into a refrigeration box with the temperature of 5 ℃ for preservation and cooling after bottling; s5, preparing the dressing: the method comprises the steps of cutting the non-setting adhesive fabric into the same size, taking out the sterilized and cooled solution, uniformly coating the solution on the non-setting adhesive fabric, enabling the ratio of the non-setting adhesive fabric to auxiliary materials to be 2:1, sealing the non-setting adhesive fabric and the auxiliary materials, wherein the processing environment of S1, S2, S3, S4 and S5 needs to be carried out in a dust-free workshop, dust-free and sterile treatment needs to be carried out in the workshop, and workers need to change clothes, wash hands, sterilize and disinfect the whole body when working.
Example three: an antibacterial hydrophilic polyurethane foam medical dressing comprises the following formula raw materials in parts by weight: 250 parts of non-setting adhesive non-woven fabric, 130 parts of deionized water, 0.3 part of monovalent silver ion solution, 3 parts of glycerol, 0.4 part of carbomer, 1.5 parts of triethanolamine, 6 parts of cationic polymer antibacterial agent, 3 parts of hydrophilic fiber, 2.5 parts of foam stabilizer, 4 parts of surfactant, 1.3 parts of silicone oil, 0.8 part of polyurethane and 50 parts of medical auxiliary material, wherein the medical auxiliary material comprises the following raw materials in parts by weight: 7 parts of overlord essence, 8 parts of white washings, 12 parts of thyme, 6 parts of moisturizing factor, 4 parts of cacumen biotae, 3 parts of tea tree oil, 4 parts of ivy and 6 parts of orange flower, wherein the surfactant is at least one of L-64, P188, PEG-400, PEG-600, PEG-800, PEG4000 and PEG6000, the surfactant is required to be sealed in a refrigerating chamber at the temperature of 10-15 ℃ for storage, and the cationic polymer antibacterial agent is one of polyhexamethylene guanidine hydrochloride, polyhexamethylene biguanide hydrochloride and polyhexamethylene guanidine phosphate.
An antibacterial hydrophilic polyurethane foam medical dressing is prepared by the following steps:
s1, crushing the material: washing white washings, thyme, cacumen biotae, tea tree oil, ivy and orange flowers in medical auxiliary materials with clean clear water, draining water in the medical auxiliary materials by using a fan after washing, spraying disinfection solution such as alcohol to disinfect the medical auxiliary materials, sealing the medical auxiliary materials after disinfection, wherein the sealing time is 30 minutes, after the medical auxiliary materials are disinfected, respectively putting the medical auxiliary materials into a wall breaking machine, adding a proper amount of deionized water to break the medical auxiliary materials, washing the medical auxiliary materials in S1 at least twice, rotating the wall breaking machine at 480r/min, and air-drying the fan for 15 minutes to ensure that the interior of the medical auxiliary materials has 35% of water content, the sprayed alcohol is required to be more than or equal to 75%, and turning the medical auxiliary materials to enable the medical auxiliary materials to be sprayed to the alcohol at every angle; s2, filtering, collecting and mixing materials: collecting liquid obtained after crushing the white washings, thyme, cacumen biotae, tea tree oil, ivy and orange flowers, filtering the liquid by using fine gauze after collection, filtering and taking out crushed impurities to leave the liquid, sequentially putting the liquid into a mixing stirrer, starting the stirrer to mix the solution, wherein the mixing time is 8 minutes, taking out the liquid after mixing, adding corresponding components of overlord and moisturizing factors, filtering the mixed solution again by using fine gauze to ensure that the content of the impurities in the solution is less than 0.1%, taking out the solution after bottling and sealing for later use, wherein the rotating speed of a S2 mixing machine is 280r/min, the specification of the gauze used during the first filtration is 200 meshes, and the specification of the gauze used during the second filtration is 400 meshes; s3, preparing auxiliary materials: taking out deionized water, monovalent silver ion solution, glycerol, carbomer, triethanolamine, cationic polymer antibacterial agent, hydrophilic fiber, foam stabilizer, surfactant, silicone oil and polyurethane with corresponding fractions, sequentially putting the deionized water, the monovalent silver ion solution, the glycerol, the carbomer, the triethanolamine, the cationic polymer antibacterial agent, the hydrophilic fiber, the foam stabilizer, the surfactant, the silicone oil and the polyurethane into a mixing and stirring device to be stirred for 30 minutes, mixing all dressing raw materials, standing the mixture for 30 minutes, adding the solution mixed with the medical auxiliary materials into the auxiliary material raw materials to be mixed and stirred for the second time, stirring the mixture for 15 minutes, and taking out the mixture for later use after all; s4, sterilizing materials: putting the mixed raw materials into a pasteurization machine, sterilizing for 12 minutes, bottling after sterilization, and putting into a refrigeration box with the temperature of 5 ℃ for preservation and cooling after bottling; s5, preparing the dressing: the method comprises the steps of cutting the non-setting adhesive fabric into the same size, taking out the sterilized and cooled solution, uniformly coating the solution on the non-setting adhesive fabric, enabling the ratio of the non-setting adhesive fabric to auxiliary materials to be 2:1, sealing the non-setting adhesive fabric and the auxiliary materials, wherein the processing environment of S1, S2, S3, S4 and S5 needs to be carried out in a dust-free workshop, dust-free and sterile treatment needs to be carried out in the workshop, and workers need to change clothes, wash hands, sterilize and disinfect the whole body when working.
It can be seen from this that: most dressings on the market are made of gauze at present, such dressings can only achieve the effect of wrapping a wound of a patient, and the antibacterial hydrophilic polyurethane foam medical dressing is prepared by adding hydrophilic fibers and monovalent silver ion solution into raw materials, on one hand, the hydrophilic fiber dressing is composed of natural fibers, can be tightly attached to the wound, has strong absorption capacity, can absorb exudate of the wound to form a layer of gel, can keep the surface of the wound moist, is beneficial to wound healing, helps to remove necrotic tissues of the wound without damaging new tissues, avoids secondary injury of the wound, on the other hand, the monovalent silver ion solution has a certain antibacterial effect, can not only play a role of sterilizing the wound in the using process, but also can prevent bacterial breeding in the subsequent process, thereby protecting the wound well, prevent the infection of the wound, the medical auxiliary material contains the cost of a large amount of Chinese herbal medicines, on one hand, the Chinese herbal medicines can inhibit fungal infection, prevent inflammation and diminish inflammation, resist bacteria and remove toxin, and can clear away deposited toxin, thereby better protecting the wound when the dressing is used, preventing the wound from secondary infection in the use process and influencing the body of a user, on the other hand, the dressing can also converge pores and moisturize, resist allergy, remove redundant grease, whiten and moisturize the skin, ensure that the skin is fresh and not greasy and contains pectin and phospholipid substances, thereby not only being capable of protecting the skin around the wound when the dressing is used for treating the wound, and being capable of improving the use effect of the medical dressing, ensuring that the auxiliary material is continuously processed in a clean and sanitary workshop when the dressing is manufactured, thereby being capable of ensuring that the dressing with high quality is manufactured, and simultaneously adopting a plurality of filtering and stirring modes during the processing, therefore, the dressing has a finer and finer effect when in use, and simultaneously, the raw materials contained in each piece of dressing are basically the same, so that the qualified quality of the produced dressing can be ensured.
Claims (8)
1. An antibacterial hydrophilic polyurethane foam medical dressing is characterized in that: the formula comprises the following raw materials in parts by weight: 200-250 parts of non-setting adhesive non-woven fabric, 110-130 parts of deionized water, 0.1-0.3 part of monovalent silver ion solution, 2-3 parts of glycerol, 0.2-0.4 part of carbomer, 0.5-1.5 parts of triethanolamine, 2-6 parts of cationic polymer antibacterial agent, 1-3 parts of hydrophilic fiber, 1.5-2.5 parts of foam stabilizer, 2-4 parts of surfactant, 0.8-1.3 parts of silicone oil, 0.5-0.8 part of polyurethane and 20-50 parts of medical auxiliary material.
2. The antibacterial hydrophilic polyurethane foam medical dressing according to claim 1, wherein: the medical auxiliary material comprises the following raw materials in parts by weight: 5-7 parts of overlord, 6-8 parts of white washington, 8-12 parts of thyme, 4-6 parts of moisturizing factor, 2-4 parts of cacumen biotae, 1-3 parts of tea tree oil, 2-4 parts of ivy and 2-6 parts of orange flower.
3. The antibacterial hydrophilic polyurethane foam medical dressing according to claim 1, wherein: the surfactant is at least one of L-64, P188, PEG-400, PEG-600, PEG-800, PEG4000 and PEG6000, and is required to be sealed in a refrigerating chamber with the temperature of 10-15 ℃ for storage.
4. The antibacterial hydrophilic polyurethane foam medical dressing according to claim 1, wherein: the cationic polymeric antimicrobial agent is one of polyhexamethylene guanidine hydrochloride, polyhexamethylene biguanide hydrochloride and polyhexamethylene guanidine phosphate.
5. The antibacterial hydrophilic polyurethane foam medical dressing according to claim 1, wherein: the preparation method comprises the following steps:
s1, crushing the material: washing white washings, thyme, cacumen biotae, tea tree oil, ivy and orange flowers in medical accessories with clean clear water, draining water in the medical accessories by using a fan after washing, spraying disinfection solution such as alcohol for disinfection treatment, sealing after disinfection for 20-30 minutes, respectively putting the accessories into a wall breaking machine after the medical accessories are disinfected, and adding a proper amount of deionized water for crushing;
s2, filtering, collecting and mixing materials: collecting liquid obtained after crushing Baishan mountain, thyme, cacumen biotae, tea tree oil, ivy and orange flowers, filtering the liquid by using fine gauze after collection, filtering and taking out crushed impurities, leaving the liquid, sequentially putting the liquid into a mixing stirrer, starting the stirrer to mix the solution, wherein the mixing time is 5-8 minutes, taking out the mixed solution after mixing, adding corresponding components of overlord and moisturizing factors, filtering the mixed solution by using fine gauze again to ensure that the impurities in the solution are less than 0.1%, taking out the solution, bottling and sealing for later use;
s3, preparing auxiliary materials: taking out deionized water, monovalent silver ion solution, glycerol, carbomer, triethanolamine, cationic polymer antibacterial agent, hydrophilic fiber, foam stabilizer, surfactant, silicone oil and polyurethane with corresponding fractions, sequentially putting the deionized water, monovalent silver ion solution, glycerol, carbomer, triethanolamine, cationic polymer antibacterial agent, hydrophilic fiber, foam stabilizer, surfactant, silicone oil and polyurethane into a mixing and stirring device for stirring for 20-30 minutes, mixing all dressing raw materials, standing for 30 minutes after mixing, adding the solution mixed with medical auxiliary materials into the auxiliary material raw materials for secondary mixing and stirring, wherein the stirring time is 10-15 minutes, and taking out all the materials for later use after fully mixing;
s4, sterilizing materials: putting the mixed raw materials into a pasteurization machine, sterilizing for 10-12 minutes, bottling after sterilization, and putting into a refrigerator at 5-10 ℃ for preservation and cooling;
s5, preparing the dressing: cutting the non-setting adhesive fabric into the same size, taking out the sterilized and cooled solution, uniformly coating the solution on the non-setting adhesive fabric to ensure that the ratio of the non-setting adhesive fabric to the auxiliary material is 2:1, and sealing.
6. The antibacterial hydrophilic polyurethane foam medical dressing according to claim 5, wherein: the medical auxiliary material in the S1 is cleaned at least twice, the rotating speed of the wall breaking machine is 350-480r/min, the air drying time of the fan is 10-15 minutes, so that the interior of the medical auxiliary material has 30-35% of water content, the sprayed alcohol needs to be more than or equal to 75%, and the medical auxiliary material needs to be turned over during spraying so that the medical auxiliary material can be sprayed to the alcohol at each angle.
7. The antibacterial hydrophilic polyurethane foam medical dressing according to claim 1, wherein: the rotation speed of the S2 mixing mechanical rotation is 260-.
8. The antibacterial hydrophilic polyurethane foam medical dressing according to claim 6, wherein: the processing environments of the S1, S2, S3, S4 and S5 must be performed in a dust-free workshop, dust-free and sterile treatment must be performed in the workshop, and workers need to change clothes, wash hands and sterilize the whole body when performing work.
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