CN112798583A - Biological sample integrated analysis device - Google Patents

Biological sample integrated analysis device Download PDF

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Publication number
CN112798583A
CN112798583A CN202110089430.5A CN202110089430A CN112798583A CN 112798583 A CN112798583 A CN 112798583A CN 202110089430 A CN202110089430 A CN 202110089430A CN 112798583 A CN112798583 A CN 112798583A
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China
Prior art keywords
container
inner container
cover
biological sample
type sealing
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Pending
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CN202110089430.5A
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Chinese (zh)
Inventor
谭曜
谢艳丽
李如松
陈平
朱杰
许赛慧
钟莺莺
王晓娟
应海松
曹国洲
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Individual
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Individual
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Priority to CN202110089430.5A priority Critical patent/CN112798583A/en
Publication of CN112798583A publication Critical patent/CN112798583A/en
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/77—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
    • G01N21/78—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator producing a change of colour
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/34—Purifying; Cleaning
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/38—Diluting, dispersing or mixing samples
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/01—Arrangements or apparatus for facilitating the optical investigation
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/01—Arrangements or apparatus for facilitating the optical investigation
    • G01N2021/0106—General arrangement of respective parts
    • G01N2021/0112—Apparatus in one mechanical, optical or electronic block

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  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Plasma & Fusion (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

The biological sample integrated analysis device comprises an inner container assembly, an outer container assembly and an analysis assembly, wherein the inner container assembly comprises an inner container, an inner cover and a filter element, a lower through hole is formed in the bottom of the inner container and is sealed by a lower pressing type sealing switch, the filter element is arranged on the inner wall of the inner container and is sealed with the inner wall, the inner cover is connected to an opening at the upper part of the inner container, an upper through hole is formed in the inner cover and is sealed by an upper pressing type sealing switch, and a sample collector; the outer container assembly comprises an outer container, an outer cover and an elastic support, wherein the elastic support is arranged at the bottom of the outer container and can elastically support the bottom of the inner container, and the upper and lower pressing type sealing switches are sealed to be opened or closed through the rotation of the outer cover on the outer container, so that the inner container and the outer container are communicated or closed; the analysis component comprises a carrier and a test strip, wherein the carrier is arranged between the inner container and the outer container, and the test strip is arranged on the inner wall or the outer wall of the carrier. It can complete the collection and analysis of biological sample and facilitate its transportation.

Description

Biological sample integrated analysis device
Technical Field
The present invention relates to a collection, transport and analysis device for biological specimens.
Background
Biological sample testing, particularly samples of stool, saliva, and the like, is commonly used for the discovery, diagnosis, and monitoring of various diseases. In most past cases, the first device was used to collect the sample and then packaged in a specific container for handling or transport. The sample is then typically dissolved in a reagent containing a component conjugated to a visually detectable label, such as a colloidal gold sample, in the laboratory to bind the analyte in the sample, and a relevant analytical test is performed by an aggregation reaction on a chromatographic strip.
In the past, different operations need various containers and testing instruments, the testing is complicated, and the testing cost is high. In order to simplify the operation process, reduce the pollution risk and reduce the testing cost, it is necessary to make innovation and improvement to integrate the functions of biological sample collection, transportation, analysis and the like into one device, so that the analysis and the test of the biological sample are more convenient and faster and the cost is reduced.
Disclosure of Invention
The present invention is directed to overcome the above-mentioned shortcomings of the prior art and to provide an integrated biological sample analyzer, which is capable of integrally collecting, transporting and analyzing a biological sample.
The technical scheme adopted by the invention for solving the technical problems is as follows:
the biological sample integrated analysis device comprises an inner container assembly, an outer container assembly and an analysis assembly arranged between the inner container assembly and the outer container assembly, wherein the inner container assembly comprises an inner container, an inner cover and a filter element, a lower through hole is formed in the bottom of the inner container, a lower pressing type sealing switch capable of sealing the through hole is arranged at the lower through hole, the filter element is arranged on the inner wall of the inner container and sealed with the inner wall, the inner cover is connected to an opening at the upper part of the inner container, an upper through hole is further formed in the inner cover, an upper pressing type sealing switch capable of sealing the upper through hole is arranged; the outer container assembly comprises an outer container, an outer cover and an elastic supporting piece, wherein the elastic supporting piece is arranged at the bottom of the outer container and can elastically support the bottom of the inner container, a lower rod capable of pushing the lower pressing type sealing switch is arranged at the bottom of the outer container, an upper rod capable of pushing the upper pressing type sealing switch is arranged in the outer cover, a mark is arranged at the joint of the outer container and the outer cover, the upper pressing type sealing switch and the lower pressing type sealing switch are not opened before or when the outer cover is positioned at the mark, the upper rod on the outer cover pushes the upper pressing type sealing switch when the outer cover continues to move downwards through the mark, the upper part of the inner container is communicated with the outer container, the lower rod at the bottom of the outer container pushes; the analysis component comprises a carrier and a test strip, wherein the carrier is arranged between the inner container and the outer container, and the test strip is arranged on the inner wall or the outer wall of the carrier.
The test strip is a test strip capable of measuring and/or displaying a specific component in a biological sample, for example, an immunochromatographic test strip capable of testing certain immune substances, and the detection of the specific component of the sample can be completed by the test strip.
The sample collector may be a porous structure at the end, and may be inserted into feces or other biological samples to collect small amount of samples, or may be various types of sample collectors.
Still fix in the above-mentioned transparent inner tube container and filter a piece, filter a piece filterable biological sample impurity, prevent that impurity from disturbing the experiment and normally going on.
When the device is used, a biological sample is collected by the sample collector on the inner cover and then placed in the inner container, so that the biological sample can be collected, and a reagent for dissolving and extracting a sample detection object and a reagent for analyzing the detection object are added, dissolved, reacted and extracted from the inner container, and then detected and displayed on the test strip.
Preferably, a magnetic stirrer is further provided and is arranged on the filter element of the inner container, so that after the biological sample is taken, the biological reagent is added into the inner container, the whole device can be arranged on the magnetic stirrer to stir, so that the biological sample is dissolved more fully and is in full contact with a visible detectable marker of the biological reagent such as a colloidal gold sample, the reaction and combination are more thorough, and the substance to be detected in the sample can be extracted better.
Preferably, the inner cap is a screw cap, and correspondingly, the mouth of the inner container is a threaded mouth, so that the matching is easier, and the sealing performance is better.
Preferably, the outer cover is an external screw cover, and correspondingly, the mouth of the outer container is a threaded mouth, so that the matching is easier, and the sealing property is better.
Preferably, the outer cover is internally provided with a step capable of pressing down the inner container, so that when the outer cover is screwed into the outer container, the inner container can be pressed down through the step, the contact area between the inner container and the outer cover is increased, and the through hole at the bottom of the inner container can be opened better and more conveniently.
More specifically, a mark is arranged on the outer cover or the mouth of the outer container, correspondingly, a designated position is arranged on the mouth of the outer container or the outer cover, and when the outer cover is screwed to the designated position to be flush with the mark, the inner container can be pressed to extract the sample; when the outer cover is further screwed to the designated position on the outer cover or the mark exceeds the mark or the designated position on the opening of the outer container, the upper rod on the outer cover opens the upper pressing type sealing switch of the inner container cover, the lower rod on the bottom of the outer container opens the lower pressing type sealing switch, so that the upper part and the lower part in the inner container are communicated with the outer container, the reagent which takes the detected substance in the inner container can flow out of the through hole at the bottom of the inner window into the outer container and flows onto the test paper to react with the reagent for displaying, and the sampling, the detection and the display of the whole biological sample are completed.
Preferably, the inner container and the outer container are transparent containers, so that the sample extraction and analysis process is more conveniently observed.
Preferably, the press type sealing switch comprises a sealing strip, a spring switch and a supporting part, wherein one end of the spring is connected with the supporting part, the other end of the spring is connected with the sealing part, and the sealing part is sealed with the through hole to be sealed.
Preferably, the carrier is a container which is adapted to the inner container and can be sleeved outside the inner container, a gap is formed between the inner wall of the carrier and the lower end of the outer wall, so that the solution can flow into the outer wall from the inner wall of the carrier, and the test paper is arranged on the outer wall of the carrier, so that the sample analyte in the solution can be aggregated and reacted with the test paper strips inlaid on the outer wall for analysis and test.
Compared with the prior art, the invention has the advantages that: the inner container can be used for conveniently collecting biological samples and is convenient to transport, and relevant substances in the biological samples can be extracted and combined with the outer container component and the analysis component to carry out detection and analysis on the biological samples, so that the collection, transport and analysis of the biological samples can be integrally completed, and the biological sample collection, transport and analysis device has the advantages of simplicity and convenience in operation, no pollution, reusability, low analysis and test cost and the like.
The device can be used for collecting, transporting and analyzing samples such as feces and saliva, is also suitable for other body fluids, can even be used for samples such as polluted food, illegal additives and the like, can completely meet the market demand, and therefore can be widely applied to departments such as hospitals, health care, disease control, environment and the like, and has wide market prospect.
Drawings
FIG. 1 is a schematic structural diagram of a biological sample integrated analysis device according to an embodiment of the present invention.
FIG. 2 is a schematic structural diagram of an analysis assembly of the integrated biological sample analyzer according to the embodiment of the present invention.
Detailed Description
The invention will be further described with reference to the following drawings and examples.
As shown in fig. 1 and 2, the integrated biological sample analyzer comprises an inner tube container assembly, an outer tube container assembly, and an analysis assembly 3.
The inner tube container assembly comprises a transparent inner container 1, an inner rotary cover 6, a magnetic stirrer 9 and a filter screen 10.
The inner screw cap 6 is screwed into the opening 64 of the transparent inner container 1 to seal the transparent inner container 1, and an upper through hole 61 is provided at the center of the inner screw cap 6 to communicate the upper part of the transparent inner container 1 with the transparent outer container 2 described below through the upper through hole 61.
The upper through hole 61 is opened and sealed by an upper press type sealing switch, which includes an upper sealing sheet 67, an upper spring 68 in this embodiment, one end of the upper spring 68 is fixed to a supporting portion 69 of the inner cap 6, and the other end is fixed to the upper sealing sheet 67 and pushes the upper sealing sheet 67 toward the upper through hole 61 to seal the upper through hole 61.
The internally threaded cap 6 fixes the sample collector 5 without additionally providing the sample collector 5, and the sample collector 5 of this embodiment has a porous structure at the end through which a sample can be inserted to collect the sample. Of course, other types of sample collectors may be used.
The filter net 10 is placed on and sealed with the inner wall of the inner container 1, through which impurities in the sample can be filtered.
The magnetic stirrer 9 is disposed on the filter screen 10, so that the magnetic stirrer 9 may be driven by the magnetic stirrer to stir, thereby better dissolving the biological sample and the reagent.
A lower through hole 11 is provided in the center of the bottom of the transparent inner container 1, and the bottom of the transparent inner container 1 is communicated with the transparent outer container 2 described below through the lower through hole 11.
The lower through hole 11 is opened and sealed by a lower press type sealing switch, which in this embodiment includes a lower sealing piece 13 and a lower spring 12, one end of the lower spring 12 is fixed on the filter screen 10, and the other end is fixed on the lower sealing piece 13 and pushes the lower sealing piece 13 to the lower through hole 11 to seal the lower through hole 11.
The transparent outer tube container 2 comprises a transparent outer container 2, an external screw cap 24 and an elastic support.
Said external screw cap (14) can be screwed on the open upper end (23) of the transparent outer container (2), a projection (15) is arranged under the centre of the external screw cap (14),
the left side and the right side of the outer rotary cover 14 are respectively provided with a step 16, the steps 16 can press down the inner rotary cover 6 and the transparent inner tube container 1, so that the contact area between the outer rotary cover 14 and the inner rotary cover 6 is larger, and the inner rotary cover 6 and the transparent inner tube container 1 are easier to press down.
The screw on the upper end of the external screw cap 14 is provided with a striking mark 17, the operation process can be indicated through the mark 17, when the biological sample needs to be sealed or dissolved, the mark 17 of the external screw cap 14 enters the pipe orifice mark 25 of the transparent outer pipe container 2, and when the biological sample needs to be detected and analyzed, the external screw cap 14 needs to be rotated until the mark 17 is below the pipe orifice mark 25.
The bottom of the transparent outer tube container 2 is provided with an elastic supporting member, which comprises a cross base 28, a material bearing spring 29 and a supporting plate 27, wherein the cross base 28 is arranged at the bottom of the transparent outer tube container 2, one end of the material bearing spring 29 is connected to the cross base 28, and the other end of the material bearing spring is connected to the supporting plate 27.
The cross base 28 has a load bearing spring 29 and a support plate 27 on the left and right.
The center of the bottom of the transparent outer tube container 2 is provided with a protrusion 20 as a switch for opening the lower through hole 11, which corresponds to the lower through hole 11 at the bottom of the transparent inner tube container 1, when the transparent inner tube container 1 moves downwards, the protrusion 20 enters the lower through hole 11 and can push open the lower sealing sheet 13, so that the transparent inner container 1 is communicated with the transparent outer tube container 2, and the reagent in the transparent inner container 1 can flow into the transparent outer tube container 2.
The analysis component 3 comprises a bearing container and a test strip, the bearing container is a sleeve 31, the test strip is a chromatographic immunological strip 35, the sleeve 31 can be sleeved outside the transparent inner container 1, the chromatographic immunological strip 35 is embedded in the outer wall 33 of the sleeve, the lower ends of the inner wall 32 and the outer wall 33 of the sleeve are communicated through a channel 34, so that a reagent in the transparent inner container 1 can flow into the outer wall from the inner wall of the sleeve 31, and the detection and display are carried out on the chromatographic immunological strip 35.
In practice, the reagent is first poured into the transparent inner tube container 1. The tail end of the sample collector 5 on the inner screw cap 6 is inserted into the feces or other biological samples to obtain a small amount of samples, and then the inner screw cap 6 with the small amount of samples is covered on the open upper end 4 of the transparent inner tube container 1 and screwed tightly. Although the center of the bottom of the transparent inner tube container 1 is provided with the lower through hole 11 and the center of the inner rotary cover 6 is provided with the rotary screw plug through hole 7, the lower through hole and the rotary screw plug through hole are respectively closed by the lower pressing type sealing switch and the upper pressing type sealing switch, so that the whole transparent inner tube container 1 is sealed, and the requirements of storing and transporting biological samples without pollution can be completely met.
After the transparent inner tube container 1 from which the biological sample has been collected is transported to the laboratory, the inner screw cap 6 can be opened, the component containing the conjugate, such as a colloidal gold-like, visually detectable label can be added to the reagent dissolved therein, allowing it to bind to the analyte in the sample, and the inner screw cap 6 can be screwed down. The relevant assay can then be performed by aggregation on the chromatographic immunostrip.
The outer wall 33 of the sleeve 3 is fixed and the sleeve 31 is arranged closely to the inner wall of the transparent outer tube container 2.
When the transparent inner tube container 1 is placed into the transparent outer tube container 2, the transparent inner tube container 1 can be supported because the left and right sides of the cross-shaped base 28 at the bottom of the transparent outer tube container 2 are respectively provided with the object bearing springs 29, so that the transparent inner tube container 1 can not descend any more. Then, an external screw cap 14 is covered on the open upper end 13 of the transparent outer tube container 2 and is screwed to the screw eye-marked mark 17 at the open upper end, and at the moment, the whole transparent inner tube container 1 is still sealed. Then the whole device is placed on a magnetic stirrer, and the magnetic stirrer switch is turned on as the magnetic stirrer 9 is arranged on the fixed filter screen 10 of the transparent inner tube container 1, the magnetic stirrer 9 starts to rotate and stir, so that the sample is fully dissolved, and fully contacts and reacts with a visible detectable marker containing conjugate such as colloidal gold, and is combined with the visible detectable marker, and the impurities of the biological sample are filtered out through the filter screen 10.
After the biological sample and the visually detectable label have reacted, the entire apparatus is removed from the magnetic stirrer. The open upper end 13 of the transparent outer vessel 2 is then further screwed on by means of the external screw cap 14, which is threaded over the open upper end by means of the eye-mark 17. At this time, the left and right bulges 16 in the external screw cap 14 can press down the whole transparent inner tube container 1, the material bearing spring 29 of the cross base 28 at the bottom of the transparent outer tube container 2 is compressed, and the whole transparent inner tube container 1 descends, so that the bulge 20 at the center of the cross base 28 at the bottom of the transparent outer tube container 2 can push open the single-phase spring switch 12 at the upper end of the lower through hole 11 at the center of the bottom of the transparent inner tube container 1; meanwhile, the bulge 15 in the external screw cap 14 can press down the sealing member at the lower end of the central through hole 7 of the internal screw cap 6 on the transparent inner tube container 1, so that the central through hole 7 of the internal screw cap 6 is opened, and the pressure of the reagent in the transparent inner tube container 1 is balanced up and down, so that the reagent can smoothly flow into the transparent outer tube container 2 from the central lower through hole 11 at the bottom of the transparent outer tube container 2, and then flow into the outer wall from the inner wall of the sleeve 31 through the channel 34 between the lower ends of the inner wall 32 and the outer wall 33 of the sleeve, and is detected and displayed on the chromatographic immunostrip 35.

Claims (10)

1. Biological sample integration analytical equipment, its characterized in that: the inner container assembly comprises an inner container, an outer container and an analysis assembly arranged between the inner container and the outer container, the inner container comprises an inner container, an inner cover and a filter element, a lower through hole is formed in the bottom of the inner container, a lower pressing type sealing switch capable of sealing the through hole is arranged in the lower through hole, the filter element is arranged on the inner wall of the inner container and sealed with the inner wall, the inner cover is connected to an opening at the upper part of the inner container, an upper through hole is further formed in the inner cover, an upper pressing type sealing switch capable of sealing the upper through hole is arranged in the; the outer container assembly comprises an outer container, an outer cover and an elastic supporting piece, wherein the elastic supporting piece is arranged at the bottom of the outer container and can elastically support the bottom of the inner container, a lower rod capable of pushing the lower pressing type sealing switch is arranged at the bottom of the outer container, an upper rod capable of pushing the upper pressing type sealing switch is arranged in the outer cover, a mark is arranged at the joint of the outer container and the outer cover, the upper pressing type sealing switch and the lower pressing type sealing switch are not opened before or when the outer cover is positioned at the mark, the upper rod on the outer cover pushes the upper pressing type sealing switch when the outer cover continues to move downwards through the mark, the upper part of the inner container is communicated with the outer container, the lower rod at the bottom of the outer container pushes; the analysis component comprises a carrier and a test strip, wherein the carrier is arranged between the inner container and the outer container, and the test strip is arranged on the outer wall of the carrier.
2. The integrated biological sample analyzer according to claim 1, wherein: the magnetic stirrer is arranged on the filter element of the inner container.
3. The integrated biological sample analyzer according to claim 1 or 2, wherein: the inner cover is a screw cover, and correspondingly, the opening of the inner container is a threaded opening.
4. The integrated biological sample analyzer according to claim 1 or 2, wherein: the outer cover is an external screw cover, and correspondingly, the mouth of the outer container is a threaded mouth.
5. The integrated biological sample analyzer according to claim 1 or 2, wherein: the outer cover is also internally provided with a step which can press down the inner container.
6. The integrated biological sample analyzer according to claim 1 or 2, wherein: a mark is arranged on the outer cover or the mouth of the outer container, correspondingly, a designated position is arranged on the mouth of the outer container or the outer cover, and when the outer cover is screwed to the designated position and is level with the mark, the inner container can be pressed tightly to extract the sample; when the outer cover is further screwed to the designated position on the outer cover or the mark exceeds the mark or the designated position on the opening of the outer container, the upper rod on the outer cover opens the upper pressing type sealing switch of the inner container cover, the lower rod on the bottom of the outer container opens the lower pressing type sealing switch, so that the upper part and the lower part in the inner container are communicated with the outer container, the reagent which takes the detected substance in the inner container can flow out of the through hole at the bottom of the inner window into the outer container and flows onto the test paper to react with the reagent for displaying, and the sampling, the detection and the display of the whole biological sample are completed.
7. The integrated biological sample analyzer according to claim 1 or 2, wherein: the inner container and the outer container are transparent containers.
8. The integrated biological sample analyzer according to claim 1 or 2, wherein: the push type sealing switch comprises a sealing strip, a spring switch and a supporting part, one end of a spring is connected with the supporting part, the other end of the spring is connected with a sealing element, and the sealing element is sealed with a through hole needing to be sealed.
9. The integrated biological sample analyzer according to claim 1 or 2, wherein: the carrier is a container matched with the inner container, the carrier can be sleeved outside the inner container, a gap is formed between the inner wall of the carrier and the lower end of the outer wall of the carrier, and the test paper is arranged on the outer wall of the carrier.
10. The integrated biological sample analyzer according to claim 1 or 2, wherein: the elastic support piece comprises a base, an object bearing spring and a supporting plate, wherein the base is arranged at the bottom of the outer tube, one end of the object bearing spring is connected to the base, and the other end of the object bearing spring is connected to the supporting plate.
CN202110089430.5A 2021-01-22 2021-01-22 Biological sample integrated analysis device Pending CN112798583A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202110089430.5A CN112798583A (en) 2021-01-22 2021-01-22 Biological sample integrated analysis device

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202110089430.5A CN112798583A (en) 2021-01-22 2021-01-22 Biological sample integrated analysis device

Publications (1)

Publication Number Publication Date
CN112798583A true CN112798583A (en) 2021-05-14

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Family Applications (1)

Application Number Title Priority Date Filing Date
CN202110089430.5A Pending CN112798583A (en) 2021-01-22 2021-01-22 Biological sample integrated analysis device

Country Status (1)

Country Link
CN (1) CN112798583A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114113598A (en) * 2021-12-07 2022-03-01 常州市口腔医院 Helicobacter pylori qualitative detection kit and use method thereof

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114113598A (en) * 2021-12-07 2022-03-01 常州市口腔医院 Helicobacter pylori qualitative detection kit and use method thereof
CN114113598B (en) * 2021-12-07 2022-05-17 常州市口腔医院 Helicobacter pylori qualitative detection kit and use method thereof

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