CN112674915B - Expandable interbody fusion cage - Google Patents
Expandable interbody fusion cage Download PDFInfo
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- CN112674915B CN112674915B CN202011502145.3A CN202011502145A CN112674915B CN 112674915 B CN112674915 B CN 112674915B CN 202011502145 A CN202011502145 A CN 202011502145A CN 112674915 B CN112674915 B CN 112674915B
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- 230000004927 fusion Effects 0.000 title claims abstract description 37
- 230000000087 stabilizing effect Effects 0.000 claims abstract description 30
- 239000007769 metal material Substances 0.000 claims description 22
- 210000000988 bone and bone Anatomy 0.000 claims description 5
- 238000011105 stabilization Methods 0.000 claims description 5
- 238000010146 3D printing Methods 0.000 claims description 4
- 229910001069 Ti alloy Inorganic materials 0.000 claims description 4
- RTAQQCXQSZGOHL-UHFFFAOYSA-N Titanium Chemical compound [Ti] RTAQQCXQSZGOHL-UHFFFAOYSA-N 0.000 claims description 4
- 230000006641 stabilisation Effects 0.000 claims description 4
- 229910052715 tantalum Inorganic materials 0.000 claims description 4
- GUVRBAGPIYLISA-UHFFFAOYSA-N tantalum atom Chemical compound [Ta] GUVRBAGPIYLISA-UHFFFAOYSA-N 0.000 claims description 4
- 239000010936 titanium Substances 0.000 claims description 4
- 229910052719 titanium Inorganic materials 0.000 claims description 4
- 230000013011 mating Effects 0.000 claims 1
- 238000000034 method Methods 0.000 abstract description 11
- 230000006378 damage Effects 0.000 abstract description 6
- 230000035807 sensation Effects 0.000 abstract description 6
- 238000011084 recovery Methods 0.000 abstract description 2
- 230000002980 postoperative effect Effects 0.000 description 3
- 230000002457 bidirectional effect Effects 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 208000027418 Wounds and injury Diseases 0.000 description 1
- 239000000956 alloy Substances 0.000 description 1
- 230000004071 biological effect Effects 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 238000002513 implantation Methods 0.000 description 1
- 208000014674 injury Diseases 0.000 description 1
- 238000003780 insertion Methods 0.000 description 1
- 230000037431 insertion Effects 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 229910052751 metal Inorganic materials 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 230000000399 orthopedic effect Effects 0.000 description 1
- 231100000915 pathological change Toxicity 0.000 description 1
- 230000036285 pathological change Effects 0.000 description 1
- 239000011148 porous material Substances 0.000 description 1
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Abstract
The invention relates to the field of medical instruments, in particular to an expandable intervertebral fusion cage. The interbody fusion cage comprises a main body mechanism, a locking mechanism, a core bar and a stabilizing mechanism, wherein the locking mechanism is stabilized in the main body mechanism through the stabilizing mechanism, the stabilizing mechanism is taken out in the operation process, the core bar is inserted into the main body mechanism, so that locking teeth of the locking mechanism expand outwards, the initial stability of a vertebral body is maintained, the use of a nail plate system is eliminated, the foreign body sensation and the secondary damage of a patient are reduced, and the recovery time is shortened.
Description
Technical Field
The invention relates to the field of medical instruments, in particular to an expandable intervertebral fusion cage.
Background
With the progress of materials science and technology, the combination of medicine and engineering is more and more compact, various difficult and complicated diseases are effectively treated, the spine is taken as one of three main pillars in orthopedics, the development is particularly rapid, and the intervertebral fusion device for the spine intervertebral fusion is widely applied to the clinical treatment of spine pathological changes.
The existing intervertebral fusion device used in clinic is often used with nail plate system, or has bidirectional screw locking. The product matched with the nail plate system is a mainstream method, and the use mode has the advantages that the nail plate system is additionally arranged outside the vertebral body, the postoperative supporting skin is obviously bulged, and the foreign body sensation in life is strong; the self-stabilization product locked by the bidirectional screw usually needs to drive the screw into the upper vertebral body and the lower vertebral body at different angles, so that the vertebral bodies are damaged secondarily.
Disclosure of Invention
The invention provides an expandable intervertebral fusion device, and aims to solve the technical problems that in the prior art, an intervertebral fusion device needs to be combined with a nail plate system, the postoperative foreign body sensation is strong, secondary damage can be caused to a vertebral body, and the like.
In order to achieve the above object, an embodiment of the present invention provides an expandable intervertebral fusion cage, which includes:
the main body mechanism is of a cuboid structure, a core bar mounting hole is formed in the side face of the cuboid structure, a plurality of locking tooth expansion holes are formed in the positions, perpendicular to the core bar mounting hole, and the locking tooth expansion holes vertically penetrate through the cuboid structure; stabilizing holes are arranged on the two side surfaces of the locking tooth expanding hole in parallel;
the locking mechanism is matched with the locking tooth mounting hole and comprises a concave upper locking tooth and a concave lower locking tooth, the two side walls of the upper locking tooth and the lower locking tooth are provided with locking holes which are meshed with each other, and a hollow part with the size smaller than that of the core rod mounting hole is formed between the meshed upper locking tooth and the meshed lower locking tooth; the stabilizing bore is concentric with the locking bore;
the stabilizing mechanism is used for stabilizing the locking mechanism before the fusion cage is used and comprises a locking branch rod, locking rods and a limiting rod, wherein one end of the locking branch rod penetrates through the locking hole and is inserted into the stabilizing hole, the other end of the locking branch rod is fixedly connected with the locking rods, the limiting rod is arranged between the two locking rods, and the locking branch rod is fixed in the locking hole;
the core bar is used for expanding and fixing the locking mechanism when the fusion cage is used; the length of the core bar is larger than that of the core bar mounting hole, one end of the core bar is matched with the core bar mounting hole, and the other end of the core bar is provided with a core bar fixing mechanism.
Furthermore, the main body mechanism further comprises a surgical tool clamping and fixing hole, the surgical tool clamping and fixing hole is overlapped with the core bar mounting hole, the diameter of the surgical tool clamping and fixing hole is larger than the width of the core bar mounting hole, and a thread structure is arranged.
Furthermore, among the stabilizing mean, the locking bar and the limiting bar adopt the detachable mode to be connected.
Furthermore, stabilizing mean still includes the connecting rod, the connecting rod has two, respectively the vertical connection on two locking levers, be provided with the gag lever post between two connecting rods.
Furthermore, the core bar is cuboid, and the end part of the end matched with the core bar mounting hole is conical.
Furthermore, the core bar fixing part comprises a sliding groove and a sliding groove hole which are arranged on the core bar, a locking plate, a limiting spring and anti-pushing teeth, wherein two ends of the limiting spring are respectively and fixedly connected with the locking plate and the anti-pushing teeth, the sliding groove is matched with the locking plate, and the sliding groove hole is matched with the anti-pushing teeth.
Furthermore, the locking plate is trapezoidal, and the spout with the locking plate matches and is trapezoidal spout.
Further, the main body mechanism is composed of a hard metal material and a porous metal material, the hard metal material is prepared to obtain a cuboid structure frame, a core bar mounting hole and a locking tooth expansion hole, and porous metal materials are arranged on each surface and inside of the cuboid structure; so as to facilitate the bone ingrowth after the operation.
Further, the hard metal material is a pure titanium or titanium alloy biological metal material, and the porous metal material is a porous tantalum biological metal material.
Further, the main body mechanism, the locking mechanism and the stabilizing mechanism are formed by 3D printing.
Has the advantages that:
(1) according to the invention, the adjacent vertebral bodies are locked by setting the plurality of locking teeth which can be expanded by inserting the core rod, the use process does not need to adopt screw fixation, the operation is simple and rapid, the damage of the adjacent vertebral bodies and the risk caused by the loosening and falling of the screws are reduced, after the fusion cage is implanted, the initial stability of the vertebral bodies can be effectively maintained, and the permanent stability can be achieved by matching with the bone ingrowth of a porous structure.
(2) The locking tooth is stabilized by the stabilizing mechanism before use, the occupied space is small, the implantation process is more convenient, the limitation of the stabilizing mechanism on the locking tooth can be removed only by simple removal in the operation process, the expansion of the locking tooth is realized by the insertion of the core rod, the locking of the vertebral body is achieved, and the operation in the operation process is convenient.
(3) According to the invention, each mechanism is processed by adopting metal materials with excellent biological properties such as pure titanium, titanium alloy, pure tantalum and the like, and porous structures consisting of porous materials are arranged in the main mechanism and on each surface, so that on one hand, the initial stability of the vertebral body can be effectively maintained, the use of a nail plate system is removed, the foreign body sensation and the secondary damage of a patient are reduced, and the recovery time is shortened.
Drawings
Figure 1 is a schematic view of an expandable interbody cage body mechanism provided by the present invention;
figure 2 is a schematic view of another expandable interbody cage body mechanism provided by the present invention;
figure 3 is a cross-sectional view of the expandable interbody cage body mechanism provided by the present invention;
figure 4 is a schematic view of an expandable intervertebral cage locking mechanism provided by the present invention;
figure 5 is a schematic view of another expandable intervertebral cage locking mechanism provided by the present invention;
figure 6 is a schematic view of a locking mechanism and stabilization mechanism combination of an expandable interbody cage provided in accordance with the present invention;
figure 7 is a cross-sectional view of a combination of a locking mechanism and a stabilization mechanism of the expandable intervertebral cage provided by the present invention;
figure 8 is a schematic illustration of a mandrel of the expandable intervertebral cage of the present invention and the cage with the mandrel inserted;
figure 9 is a schematic illustration of a core rod of the expandable intervertebral cage provided by the present invention;
figure 10 is a schematic illustration of a core rod locking mechanism of the expandable intervertebral cage provided by the present invention.
[ description of reference ]
1. A main body mechanism; 1-1, porous structure; 1-2, clamping and fixing holes for surgical tools; 1-3, core bar mounting holes; 1-4, locking tooth expansion holes; 1-5 locking holes; 2. a locking mechanism; 2-1 locking teeth; 2-2 locking holes; 3. a core bar; 3-1, preventing pushing teeth; 3-2, a limiting spring; 3-3, locking plate; 3-4, a chute; 3-5, sliding groove holes; 4. a stabilizing mechanism and a 4-1 limiting rod; 4-2, a locking rod; 4-3, connecting rods; 4-4, locking the branch.
Detailed Description
In order to make the technical problems, technical solutions and advantages of the present invention more apparent, the following detailed description is given with reference to the accompanying drawings and specific embodiments.
The invention provides an expandable intervertebral fusion device, and aims to solve the technical problems that in the prior art, an intervertebral fusion device needs to be combined with a nail plate system, the postoperative foreign body sensation is strong, secondary damage can be caused to a vertebral body, and the like.
As shown in figures 1-10, the embodiment of the invention provides an expandable intervertebral fusion device which specifically comprises a main body mechanism 1, a locking mechanism 2, a core rod 3 and a stabilizing mechanism 4.
As shown in fig. 2 and 3, the main body mechanism 1 is a rectangular parallelepiped structure with rounded corners, and is composed of a hard metal material and a porous metal material, the hard metal material is prepared to obtain a rectangular parallelepiped structure frame, a core rod mounting hole and a locking tooth expansion hole, and porous metal materials are arranged on each surface and inside of the rectangular parallelepiped structure to form a porous structure 1-1 for bone ingrowth after an operation; the side surface of the cuboid structure is provided with a core bar mounting hole 1-3, a plurality of locking tooth expansion holes 1-4 are vertically arranged with the core bar mounting hole 1-3, generally 4 locking tooth expansion holes are arranged, the locking tooth expansion holes 1-4 vertically penetrate through the upper surface and the lower surface of the cuboid structure, and the side surface of the locking tooth expansion holes 1-4 is provided with stabilizing holes 1-5, so that the operation is more convenient in the operation process, the positions of the locking tooth expansion holes 1-4 and the core bar mounting hole are provided with operation tool clamping fixing holes 1-2, the diameter of the operation tool clamping fixing holes 1-2 is larger than the width of the core bar mounting holes 1-3, and the fusion device is provided with a thread structure, and the fusion device can be fixed 1-2 on an operation tool through the operation tool clamping fixing holes.
The locking mechanism is matched with the locking tooth mounting hole, as shown in fig. 4 and 5, the locking mechanism comprises two locking teeth 2-1 which are of a concave structure and are divided into an upper locking tooth and a lower locking tooth, locking holes 2-2 are formed in two side walls of the upper locking tooth 2-1 and the lower locking tooth 2-1, after concave surfaces of the upper locking tooth 2-1 and the lower locking tooth are meshed with each other, the locking holes 2-2 are superposed, the upper locking tooth and the lower locking tooth are fixed conveniently, the locking holes 2-1 and the stabilizing holes 1-5 are concentric, the locking teeth 2-1 are stabilized in the locking tooth expansion holes 1-4, and a hollow part with the size smaller than that of the core rod mounting hole 1-3 is formed between the meshed upper locking tooth 2-1 and the meshed lower locking tooth; the width of the hollow part is larger than the sum of the thicknesses of the side walls of the upper locking tooth 2-1 and the lower locking tooth 2-1 after meshing, so that the fixing mechanism of the locking teeth can be conveniently removed.
The stabilizing mechanism mainly uses the stability of a locking mechanism before the intervertebral fusion device is used, namely the stability before the locking teeth are not expanded, as shown in figures 6 and 7, the stabilizing mechanism comprises a locking branch rod 4-4, a locking rod 4-2 and a limiting rod 4-1, the locking branch rod 4-4 is conical, the number of the locking branch rods 4-4 is twice of the number of the locking teeth, one end of the locking branch rod 4-4 penetrates through the locking hole 2-2 and is inserted into a stabilizing hole 1-5, the length of the locking branch rod 4-4 is slightly larger than the sum of the thicknesses of the side walls of the upper locking tooth 2-1 and the lower locking tooth 2-1 after meshing and is smaller than the width of a hollow part after the upper locking tooth 2-1 and the lower locking tooth 2-1 are meshed, so as to facilitate the removal of the stabilizing mechanism, the other end of the locking branch rod 4-4 is fixedly connected with the locking rod 4-2, two locking rods are fixedly arranged from two sides of the locking teeth, the limiting rod is arranged between the two locking rods and is provided with a limiting rod 4-1 used for limiting the distance between the two locking rods, so that the locking branch rod 4-4 is fixed in the locking hole 2-2 to prevent the locking tooth 2-1 from moving, the limiting rod 4-1 and the locking rod 4-2 are detachably connected in order to facilitate the removal of the stabilizing mechanism in the operation process, the limiting rod 4-1 only needs to be removed when in use, and then the locking branch rod reversely exits from the locking hole through the locking rod 4-2; in order to facilitate the operation of the surgical tool, the locking mechanism is further provided with two connecting rods 4-3, the two connecting rods 4-3 are respectively and vertically connected to the two locking rods 4-2, the limiting rod 4-1 is arranged between the two connecting rods 4-3, and the connecting rod 4-3 and the locking rod 4-2 can be detachably connected.
The core bar 3 is used for expanding and fixing the locking mechanism 2 when the fusion cage is used, as shown in fig. 8-10, the length of the core bar 3 is greater than that of the core bar mounting hole 1-3, the core bar is cuboid, and the end part of the end matched with the core bar mounting hole is conical, so that the core bar can be conveniently inserted into the hollow between the upper locking tooth 2-1 and the lower locking tooth 2-1, and the locking teeth 2-1 can be rapidly expanded; the other end of the core bar 3 is provided with a core bar fixing mechanism, the core bar fixing mechanism comprises a chute 3-4 and a chute hole 3-5 which are arranged on the core bar, a locking plate 3-3, a limit spring 3-2 and an anti-push tooth 3-1, one end of the limit spring 3-2 is fixed in a groove in the middle of the anti-push tooth 3-1, the other end is fixed in a groove in the middle of the locking plate 3-3, the locking plate 3-3 is matched with the chute 3-4, the anti-push tooth 3-1 is matched with the chute hole 3-5, the anti-push tooth 3-1 can just penetrate through the chute hole 3-5, for more convenient fixing of the core bar in the operation process, the locking plate 3-3 and the chute are set to be in a ladder shape, and the locking plate 3-3 is slid from a wide groove to a narrow groove of the chute during fixing, when the anti-pushing teeth 3-1 are locked in the sliding groove holes 3-5, the limiting springs 3-2 are in a release state, and the fusion device core rod part 3 is assembled.
In the application process, firstly, a main body mechanism 1, a locking mechanism 2 and a stabilizing mechanism 4 in the interbody fusion cage are integrally formed into a component 1 by 3D printing, a core rod 3 is made of a biological alloy material, the sterilized component 1 is locked by an operation clamping tool and implanted into a focus part of a patient, then a connecting rod 4-3 and a limiting rod 4-1 in the stabilizing mechanism are removed, a locking rod 4-2 is grabbed and retreated from a locking branch rod 4-4 in the opposite direction, and then the locking rod 4-2 is taken out; and finally, inserting the core rod 3 into the center of the fusion device through the core rod mounting holes 1-3, expanding the locking teeth 2-1 to the upper surface and the lower surface of the fusion device through the locking tooth expansion holes 1-4, and reversely locking the core rod through the locking plates 3-3 to prevent the core rod from returning.
The expandable interbody fusion cage provided by the invention is made of metal materials with excellent biological performance, such as pure titanium, titanium alloy, pure tantalum and the like, by adopting a metal 3D printing technology, and the expandable interbody fusion cage is composed of a plurality of parts, can be used independently, and reduces the foreign body sensation of a patient; in the clinical use process, the screw fixation is not needed, the operation is simple and quick, and the risk caused by the injury of adjacent vertebral bodies and the falling of the screws due to the looseness is reduced; after the product is implanted into the intervertebral space, the locking teeth expand to lock the product and the adjacent vertebral bodies, so that the initial stability of the vertebral bodies is effectively maintained, and the product is matched with bone ingrowth of a porous structure to achieve permanent stability.
While the foregoing is directed to the preferred embodiment of the present invention, it will be understood by those skilled in the art that various changes and modifications may be made without departing from the spirit and scope of the invention as defined in the appended claims.
Claims (10)
1. An expandable intervertebral cage, which is characterized by comprising:
the main body mechanism is of a cuboid structure, a core bar mounting hole is formed in the side face of the cuboid structure, a plurality of locking tooth expansion holes are formed in the positions, perpendicular to the core bar mounting hole, and the locking tooth expansion holes vertically penetrate through the cuboid structure; stabilizing holes are arranged on the two side surfaces of the locking tooth expanding hole in parallel;
the locking mechanism is matched with the locking tooth expansion hole and comprises a concave upper locking tooth and a concave lower locking tooth, locking holes are formed in two side walls of the upper locking tooth and the lower locking tooth and are meshed with each other, and a hollow part with the size smaller than that of the core rod mounting hole is formed between the meshed upper locking tooth and the meshed lower locking tooth; the stabilizing bore is concentric with the locking bore;
the stabilizing mechanism is used for stabilizing the locking mechanism before the fusion cage is used and comprises a locking branch rod, two locking rods and a limiting rod, wherein one end of the locking branch rod penetrates through the locking hole and is inserted into the stabilizing hole, the other end of the locking branch rod is fixedly connected with the locking rods, the limiting rod is arranged between the two locking rods, and the locking branch rod is fixed in the locking hole;
the core bar is used for expanding and fixing the locking mechanism when the fusion cage is used; the length of the core bar is larger than that of the core bar mounting hole, one end of the core bar is matched with the core bar mounting hole, and the other end of the core bar is provided with a core bar fixing mechanism.
2. The expandable intervertebral fusion of claim 1 wherein the body mechanism further comprises a surgical tool holding fixation hole overlapping the mandrel mounting hole, the surgical tool holding fixation hole having a diameter greater than a width of the mandrel mounting hole and being provided with a threaded configuration.
3. The expandable intervertebral fusion of claim 1 wherein the locking rod of the stabilization mechanism is removably connected to the stop rod.
4. The expandable intervertebral fusion device of claim 2, wherein the stabilizing mechanism further comprises two connecting rods, the two connecting rods are vertically connected to the two locking rods respectively, and a limiting rod is arranged between the two connecting rods.
5. The expandable intervertebral fusion of claim 1 wherein the core rod is rectangular and the end of the core rod at the mating end with the core rod mounting hole is tapered.
6. The expandable interbody fusion cage of claim 1, wherein the core bar fixing mechanism comprises a sliding groove and a sliding groove hole arranged on the core bar, and a locking plate, a limiting spring and an anti-pushing tooth, wherein two ends of the limiting spring are fixedly connected with the locking plate and the anti-pushing tooth respectively, the sliding groove is matched with the locking plate, and the sliding groove hole is matched with the anti-pushing tooth.
7. The expandable interbody fusion cage of claim 6, wherein the locking plate is trapezoidal shaped, and the sliding slot mates with the locking plate in a trapezoidal sliding slot.
8. The expandable intervertebral fusion device according to claim 1, wherein the main body mechanism is composed of a hard metal material and a porous metal material, the hard metal material is prepared to obtain a cuboid structural frame and a core rod mounting hole and a locking tooth expansion hole, and porous metal materials are arranged on each surface and inside of the cuboid structure; so as to facilitate the bone ingrowth after the operation.
9. The expandable intervertebral fusion of claim 8 wherein the hard metal material is a pure titanium or titanium alloy bio-metal material and the porous metal material is a porous tantalum bio-metal material.
10. The expandable intervertebral cage of claim 1 wherein the body mechanism, locking mechanism, and stabilization mechanism are formed using 3D printing.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202011502145.3A CN112674915B (en) | 2020-12-17 | 2020-12-17 | Expandable interbody fusion cage |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202011502145.3A CN112674915B (en) | 2020-12-17 | 2020-12-17 | Expandable interbody fusion cage |
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| CN112674915A CN112674915A (en) | 2021-04-20 |
| CN112674915B true CN112674915B (en) | 2022-09-23 |
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| CN202011502145.3A Active CN112674915B (en) | 2020-12-17 | 2020-12-17 | Expandable interbody fusion cage |
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| US9198774B2 (en) * | 2013-11-21 | 2015-12-01 | Perumala Corporation | Intervertebral disk cage and stabilizer |
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| CN203001182U (en) * | 2012-03-28 | 2013-06-19 | 北京爱康宜诚医疗器材股份有限公司 | Adjustable interbody fusion cage |
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| CN112674915A (en) | 2021-04-20 |
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Address after: 410600 room 205, building 1, Hunan University Science and Technology Industrial Park, No. 001, Jinzhou North Road, Ningxiang high tech Industrial Park, Changsha City, Hunan Province Applicant after: Hunan Huaxiang Medical Technology Co.,Ltd. Address before: 410600 room 205, building 1, Hunan University Science and Technology Industrial Park, No. 001, Jinzhou North Road, Ningxiang high tech Industrial Park, Changsha City, Hunan Province Applicant before: HUNAN HUAXIANG ZENGLIANG TECHNOLOGY CO.,LTD. |
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| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| CB03 | Change of inventor or designer information | ||
| CB03 | Change of inventor or designer information |
Inventor after: Zou Weimin Inventor after: Jiang Jinwei Inventor after: Guo Kaixuan Inventor after: Hou Kai Inventor after: Wang Guohua Inventor after: Liu Jiang Inventor after: Song Kun Inventor before: Zou Weimin Inventor before: Song Kun Inventor before: Xiang Xiaowei Inventor before: Shen Yu Inventor before: Jiang Jinwei Inventor before: Guo Kaixuan Inventor before: Wang Kai Inventor before: Hou Kai Inventor before: Wang Guohua Inventor before: Liu Jiang |
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| CP03 | Change of name, title or address | ||
| CP03 | Change of name, title or address |
Address after: No. 58 Jinshui West Road, Ningxiang High tech Industrial Park, Changsha City, Hunan Province, 410604 Patentee after: Hunan Huaxiang Medical Technology Co.,Ltd. Country or region after: China Address before: 410600 room 205, building 1, Hunan University Science and Technology Industrial Park, No. 001, Jinzhou North Road, Ningxiang high tech Industrial Park, Changsha City, Hunan Province Patentee before: Hunan Huaxiang Medical Technology Co.,Ltd. Country or region before: China |