CN112656709A - Skin care compositions and uses thereof - Google Patents
Skin care compositions and uses thereof Download PDFInfo
- Publication number
- CN112656709A CN112656709A CN202110014441.7A CN202110014441A CN112656709A CN 112656709 A CN112656709 A CN 112656709A CN 202110014441 A CN202110014441 A CN 202110014441A CN 112656709 A CN112656709 A CN 112656709A
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- CN
- China
- Prior art keywords
- skin care
- salt
- hyaluronic acid
- molecular weight
- care composition
- Prior art date
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- ADNPLDHMAVUMIW-CUZNLEPHSA-N substance P Chemical compound C([C@@H](C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCSC)C(N)=O)NC(=O)[C@H](CC=1C=CC=CC=1)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H]1N(CCC1)C(=O)[C@H](CCCCN)NC(=O)[C@H]1N(CCC1)C(=O)[C@@H](N)CCCN=C(N)N)C1=CC=CC=C1 ADNPLDHMAVUMIW-CUZNLEPHSA-N 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- 238000010998 test method Methods 0.000 description 1
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- 230000002936 tranquilizing effect Effects 0.000 description 1
- VHBFFQKBGNRLFZ-UHFFFAOYSA-N vitamin p Natural products O1C2=CC=CC=C2C(=O)C=C1C1=CC=CC=C1 VHBFFQKBGNRLFZ-UHFFFAOYSA-N 0.000 description 1
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Images
Landscapes
- Cosmetics (AREA)
Abstract
The invention discloses a skin care composition and application thereof. The skin care composition provided by the invention can restore the grains of the scalp by combining the humectant and the soothing agent, so that the scalp presents fine grains with a net shape and a regular arrangement. In addition, the skin care composition provided by the application can also improve the moisture content of the skin and has a certain relieving effect on the condition of red scalp.
Description
Technical Field
The invention relates to the technical field of daily chemical industry, in particular to a skin care composition and application thereof.
Background
The scalp is a part of the human skin, but is very different from the facial skin. For example, the thickness of the stratum corneum of the scalp is only about 1.476mm, which is thinner than the thickness of the common facial skin of 1.533 mm; the sebaceous glands of the scalp are larger, more and more active, so that the secretion of grease is more vigorous; the proportion of malassezia that feeds on sebum in the microorganisms colonized on the scalp is much higher than that of the skin, and so on. Under the influence of factors such as living environment, stress, diet and the like, scalp problems of modern people are increasingly severe, and problems such as sensitivity, red blood streak, dandruff, alopecia, early graying and the like are more and more. However, most people often keep on the aspect of using shampoo for scalp care, and special care products aiming at scalp characteristics are also lacking in the market, and particularly, comprehensive care schemes aiming at sensitive and dry scalp, red blood streak and the like are lacking.
Disclosure of Invention
In order to solve the above problems, the present invention provides a skin care composition, particularly for the care of the skin of the head.
The scalp can show the phenomena of reddish scalp, red blood silk of the scalp and the like due to the damage of a barrier, external stimulation, oxidative stress pressure and the like, and the lines of the scalp can also become shallow or even disappear.
The specific technical scheme of the invention is as follows:
1. a skin care composition comprising a moisturizing agent and a soothing agent.
2. The skin care composition according to item 1, wherein the humectant is 0.001 to 20%, preferably 0.1 to 5%, further 0.1 to 0.5% by mass in the skin care composition;
the content of the soothing agent is 0.001-20%, preferably 0.1-5%, and more preferably 0.1-0.5%.
3. The composition according to item 1 or 2, wherein the humectant is a biomacromolecule polysaccharide, preferably the biomacromolecule polysaccharide is selected from hyaluronic acid or a salt thereof, cellulose and a derivative thereof, guar gum, trehalose, rhamnose or biosaccharide gum, and more preferably hyaluronic acid or a salt thereof.
4. The composition according to item 3, the molecular weight of the hyaluronic acid or salt thereof is 0.5w-180wDa, preferably 0.5w-150wDa, and more preferably 1w-130 wDa.
5. The skin care composition according to item 3 or 4, wherein the hyaluronic acid or salt thereof comprises high molecular weight hyaluronic acid or salt thereof and low molecular weight hyaluronic acid or salt thereof, preferably, the mass ratio of the high molecular weight hyaluronic acid or salt thereof to the low molecular weight hyaluronic acid or salt thereof is 1:0.1-10, preferably 1:0.5-5, and more preferably 1: 1-3.
6. The skin care composition according to item 5, wherein the high molecular weight hyaluronic acid or salt thereof has a molecular weight of 110w-180wDa, preferably 110w-150wDa, more preferably 110w-130 wDa;
the molecular weight of the low molecular weight hyaluronic acid or the salt thereof is 0.5w-50wDa, preferably 0.5w-30wDa, and more preferably 0.5w-1 wDa.
7. The skin care composition according to any one of items 1 to 6, wherein the soothing agent is selected from one or more of dipotassium glycyrrhizinate, carboxymethyl chitin, carboxymethyl chitosan, ectoin, comfrey extract, chamomile extract and citrus fruit extract, preferably dipotassium glycyrrhizinate and ectoin.
8. The skin care composition according to item 7, wherein the mass ratio of the dipotassium glycyrrhizinate to the ectoin is 1: 1-3.
9. A skin care product comprising the skin care composition of any one of items 1 to 8 and an adjuvant, preferably the skin care composition is 1 to 100%, preferably 30 to 60% by mass of the skin care product.
10. The skin care product of claim 9, wherein the skin care product is a lotion, serum, shampoo, or conditioner.
11. A method for enhancing skin care by topically applying the skin care product of item 9 or 10 to the skin of a patient.
12. Use of the skin care composition according to any one of items 1 to 8 in the field of skin care products, preferably the skin care product is a lotion, a serum, a shampoo or a conditioner.
ADVANTAGEOUS EFFECTS OF INVENTION
Since the skin texture under the skin mirror is due to the skin hills and furrows, young healthy skin has a reticular, fine, relatively regular skin texture. In the aged skin, although skin wrinkles are clearly visible to the naked eye, the distance between the skin dome and the skin groove is rather increased, the skin texture is thickened, and it is found that the skin wrinkles of the scalp are not noticeable or even disappear in the case where the scalp has discomfort such as inflammation, redness and swelling. Therefore, the skin care composition provided by the invention can recover the grains of the scalp, so that the scalp presents fine and net-shaped grains which are arranged orderly. In addition, the skin care composition provided by the application can also improve the moisture content of the skin and has a certain relieving effect on the condition of red scalp.
Drawings
Fig. 1 is a schematic representation of the skin texture changes in test example 3 using the skin care composition described in example 8.
Detailed Description
The present invention is described in detail in the following description of embodiments with reference to the figures, in which like numbers represent like features throughout the figures. While specific embodiments of the invention are shown in the drawings, it should be understood that the invention may be embodied in various forms and should not be construed as limited to the embodiments set forth herein. Rather, these embodiments are provided so that this disclosure will be thorough and complete, and will fully convey the scope of the invention to those skilled in the art.
It should be noted that certain terms are used throughout the description and claims to refer to particular components. As one skilled in the art will appreciate, various names may be used to refer to a component. This specification and claims do not intend to distinguish between components that differ in name but not function. In the following description and in the claims, the terms "include" and "comprise" are used in an open-ended fashion, and thus should be interpreted to mean "include, but not limited to. The description which follows is a preferred embodiment of the invention, however, the description is given for the purpose of illustrating the general principles of the invention and not for the purpose of limiting the scope of the invention. The scope of the present invention is defined by the appended claims.
The present invention provides a skin care composition comprising a moisturizing agent and a soothing agent.
The moisturizer refers to a cosmetic material which can increase or maintain the moisture of the upper layer of the skin over a wide range of relative humidity in the product and over a long period of time, and is a skin conditioner which has low volatility, can retain moisture, and is occluded on the surface of the skin.
The soothing agent refers to cosmetic raw materials capable of eliminating skin inflammation, tranquilizing and relieving irritation.
In a preferred embodiment of the present invention, wherein the skin care composition is comprised of a moisturizing agent, a soothing agent, and a solvent, the solvent may be, for example, water or an alcoholic solvent, the alcoholic solvent may be, for example, glycerin, ethanol, propylene glycol, butylene glycol, sorbitol, and the like.
In a preferred embodiment of the present invention, wherein the moisturizer is 0.001 to 20%, preferably 0.1 to 5%, further 0.1 to 0.5% by mass of the skin care composition;
the content of the soothing agent is 0.001-20%, preferably 0.1-5%, and more preferably 0.1-0.5%.
For example, the moisturizer can be 0.001%, 0.005%, 0.01%, 0.05%, 0.1%, 0.5%, 1%, 2%, 3%, 4%, 5%, 6%, 7%, 8%, 9%, 10%, 11%, 12%, 13%, 14%, 15%, 16%, 17%, 18%, 19%, 20%, etc. by mass percentage in the skin care composition;
the soothing agent can be 0.001%, 0.005%, 0.01%, 0.05%, 0.1%, 0.5%, 1%, 2%, 3%, 4%, 5%, 6%, 7%, 8%, 9%, 10%, 11%, 12%, 13%, 14%, 15%, 16%, 17%, 18%, 19%, 20%, etc.
In a preferred embodiment of the present invention, the humectant is a biomacromolecule polysaccharide, preferably, the biomacromolecule polysaccharide is selected from hyaluronic acid or a salt thereof, cellulose and a derivative thereof, guar gum, trehalose, rhamnose or biosaccharide gum, and more preferably hyaluronic acid or a salt thereof.
The biomacromolecule polysaccharide refers to: polysaccharides of higher molecular weight consisting of single or multiple saccharide units.
The cellulose and the derivatives thereof refer to macromolecular polysaccharide consisting of glucose, and can be modified by hydroxypropylation, hydroxyethylation, cationization and the like to be derived into macromolecular polysaccharide polymers with different viscosities, water solubility, transparency, lubrication degree and moisture retention.
The guar gum is a linear natural galactomannan gum which is mainly obtained by hydrolyzing the endosperm of the seeds of guar (Cyamopsis tetragonoloba), the chemical structure of the guar gum is a D-mannopyranose linear main chain which is formed by connecting a chains 1 and 4, and 1 alpha-D galactose short branched chain is connected on the main chain at the interval of 2 mannose residues on average.
The trehalose is also called rhaponticum uniflorum sugar and mycose, is a non-reducing disaccharide consisting of two glucose molecules, is a typical stress metabolite, can form a unique protective film on the cell surface under severe environmental conditions of high temperature, high cold, high osmotic pressure, drying and dehydration and the like, and effectively protects a biological molecular structure from being damaged, so that the life process and biological characteristics of a living body are maintained.
The rhamnose is also called 6-deoxy-L-mannose, is an organic compound with molecular formula C6H12O5It is a substance widely existing in plant polysaccharides, glycosides, plant gums and bacterial polysaccharides.
The biological carbohydrate gum is a polysaccharide formed by linearly arranging one or more of fucose, galactose and galacturonic acid, can be obtained by microbial fermentation, and has effects of relieving, inhibiting P substance release, relieving nerve, keeping moisture, and promoting keratinocyte differentiation.
In a preferred embodiment of the invention, the molecular weight of the hyaluronic acid or salt thereof is 0.5w-180wDa, preferably 0.5w-150wDa, and more preferably 1w-130 wDa.
For example, the molecular weight of the hyaluronic acid or salt thereof may be 0.5wDa, 1wDa, 5wDa, 10wDa, 15wDa, 20wDa, 30wDa, 40wDa, 50wDa, 100wDa, 110wDa, 120wDa, 130wDa, 140wDa, 150wDa, 160wDa, 170wDa, 180wDa, and the like.
The salt of hyaluronic acid is a metal salt of hyaluronic acid, such as potassium, sodium, calcium, magnesium or zinc salt of hyaluronic acid, preferably sodium salt of hyaluronic acid.
In a preferred embodiment of the present invention, wherein the hyaluronic acid or the salt thereof comprises a high molecular weight hyaluronic acid or the salt thereof and a low molecular weight hyaluronic acid or the salt thereof, preferably, the mass ratio (m) of the high molecular weight hyaluronic acid or the salt thereof to the low molecular weight hyaluronic acid or the salt thereof isHigh molecular weight hyaluronic acid or salt thereof：mLow molecular weight hyaluronic acid or salt thereof) Is 1:0.1-10, preferably 1:0.5-5, and more preferably 1: 1-3.
For example, the mass ratio (m) of the high molecular weight hyaluronic acid or salt thereof to the low molecular weight hyaluronic acid or salt thereofHigh molecular weight hyaluronic acid or salt thereof：mLow molecular weight hyaluronic acid or salt thereof) May be 1:0.1, 1:0.5, 1:1, 1:2, 1:3, 1:4, 1:5, 1:6, 1:7, 1:8, 1:9, 1:10, etc.
In a preferred embodiment of the present invention, wherein the molecular weight of the high molecular weight hyaluronic acid or salt thereof is 110w-180wDa, preferably 110w-150wDa, more preferably 110w-130 wDa;
the molecular weight of the low molecular weight hyaluronic acid or the salt thereof is 0.5w-50wDa, preferably 0.5w-30wDa, and more preferably 0.5w-1 wDa.
For example, the high molecular weight hyaluronic acid or salt thereof has a molecular weight of 110wDa, 115wDa, 120wDa, 125wDa, 130wDa, 135wDa, 140wDa, 145wDa, 150wDa, 155wDa, 160wDa, 165wDa, 170wDa, 175wDa, 180wDa, etc.;
the molecular weight of the low molecular weight hyaluronic acid or the salt thereof is 0.5wDa, 1wDa, 5wDa, 10wDa, 15wDa, 20wDa, 30wDa, 40wDa, 50wDa and the like.
In a preferred embodiment of the present invention, the soothing agent may be, but is not limited to, dipotassium glycyrrhizinate, carboxymethyl chitin, carboxymethyl chitosan, ectoin, lithospermum extract, chamomile extract, citrus fruit extract, etc., and more preferably dipotassium glycyrrhizinate and ectoin.
The dipotassium glycyrrhizinate is a derivative of glycyrrhizin (glycyrrhizic acid) at the root and the stem of liquorice, can be used as a skin conditioner, has the effects of bacteriostasis, red swelling reduction, inflammation diminishing, healing, detoxification, allergy resistance, irritation resistance and oil control, is suitable for allergic skin, can effectively prevent sensitive inflammation phenomenon when the skin is stimulated, has the effects of diminishing inflammation and calming on inflammation caused by sunshine, and is often used in antiallergic and repairing cosmetics.
The carboxymethyl chitin can be formed by hydrolyzing chitin contained in a shell of crustacean under an alkaline condition to remove partial acetyl groups to form chitosan, and then reacting with chloroacetic acid under a strong alkaline condition to introduce carboxymethyl. Can be N-carboxymethyl chitosan, O-carboxymethyl chitosan or N, O-carboxymethyl chitosan. The carboxymethyl chitin can be used as wound healing dressing to effectively promote wound healing.
The carboxymethyl chitosan is subjected to deacetylation treatment on the basis of carboxymethyl chitosan, has better water solubility, and has obvious anti-inflammatory and relieving effects.
The radix Arnebiae extract is active ingredient extracted from traditional Chinese medicine radix Arnebiae, and is named as shikonin, and shikonin. Can resist inflammation, repair epidermis damage and has certain antioxidant activity.
The chamomile extract is an active ingredient extracted from dried flowers of chamomile (Matricaria) of Matricaria of Compositae, contains components such as flavone, saponin, polysaccharide, volatile oil and the like, and has a remarkable relieving effect.
The citrus fruit extract is an active ingredient extracted from traditional analgesic Chinese herbal medicine 'green tangerine peel', namely immature citrus fruits, contains abundant flavonoid and alkaloid components, and has a relieving effect.
The ectoine is an amphoteric rare amino acid, 1, 4, 5, 6-tetrahydro-2-methyl-4-pyrimidinecarboxylic acid, produced by bacteria in the extreme environment of life. Ectoine is the most widely distributed compatible solute in the bacterial community discovered at present, is compatible with the metabolism in cells, does not influence the biomacromolecule function or physiological function of the cells, and is an important osmotic pressure compensation solute. Ectoin has the functions of protecting epithelial cells, stabilizing cell membranes, moistening skin and reducing inflammation.
In a preferred embodiment of the present invention, wherein the weight ratio (m) of dipotassium glycyrrhizinate to ectoin isGlycyrrhizic acid dipotassium salt：mEctoin) Is 1: 1-3.
For example, the mass ratio (m) of the dipotassium glycyrrhizinate to the ectoinGlycyrrhizic acid dipotassium salt：mEctoin) May be 1:1, 1:2, 1:3, etc.
The skin care composition provided by the invention can play a comprehensive care role in moisturizing, relieving itching, controlling oil, relieving, removing red blood streak, recovering skin lines, recovering skin pH balance and the like, so that the scalp is recovered.
Scalp oil secretion is generally more vigorous than that of the face, and redundant oil is easily converted into peroxidized fatty acid represented by peroxidized squalene under the oxidation pressure of the scalp oil per se and the outside, so that the scalp is stimulated. Or the oil and fat can be used as nutrient substance by malassezia and other fungi, and then can secrete metabolite which can stimulate the skin. The metabolic products are used as inflammatory factors, can easily cause discomfort symptoms such as scalp itching, red swelling, inflammation and the like, and simultaneously have the phenomena of reduced moisture content of scalp surface, increased transdermal moisture loss, abnormal pH value, abnormal grease secretion, abnormal scalp appearance and the like. After the barrier is damaged, the arrangement of cells on the scalp surface is loose, the colonization of harmful bacteria is easier to occur, the number of the harmful bacteria is increased, the secretion of irritant metabolites is further aggravated, and the damage of the scalp barrier, the aggravation of inflammation, the abnormal secretion of scalp grease and the like are caused. Simple moisture retention or simple soothing cannot effectively solve the problem of scalp barrier damage. After the long-acting and instant moisturizing with different molecular weights and different penetration depths is combined with the soothing components, the scalp inflammation condition is rapidly relieved, the moisture content of scalp surface cells is recovered, the oil secretion tends to be normal, and the overall health condition of the scalp is recovered.
The invention provides a preparation method of the skin care composition, which comprises the following steps: the humectant and the soothing agent are uniformly dissolved and dispersed in the solvent.
The solvent may be, for example, water or an alcohol solvent, and the alcohol solvent may be, for example, glycerin, ethanol, propylene glycol, butylene glycol, sorbitol, or the like.
The humectant is a biological macromolecular polysaccharide, preferably, the biological macromolecular polysaccharide is selected from hyaluronic acid or salt thereof, cellulose and derivatives thereof, guar gum, trehalose, rhamnose or biological carbohydrate gum, and more preferably hyaluronic acid or salt thereof.
The soothing agent may be, but is not limited to, dipotassium glycyrrhizinate, carboxymethyl chitin, carboxymethyl chitosan, ectoin, lithospermum extract, chamomile extract, citrus fruit extract, etc., and more preferably dipotassium glycyrrhizinate and ectoin.
The invention provides a skin care product, which comprises the skin care composition and auxiliary materials, wherein the skin care composition accounts for 1-100% of the skin care product, and the skin care composition accounts for 30-60% of the skin care product.
The adjuvants are well known to those skilled in the art, and may include, for example, emulsifiers, fats and oils, preservatives, chelating agents, fragrances, colorants, thickeners, and the like.
In a preferred embodiment of the present invention, the skin care product is a lotion, essence, shampoo or conditioner.
The present invention provides a method for enhancing skin care by topically applying the skin care products described above to the skin of a patient.
The invention provides application of the skin care composition in the field of skin care products, and preferably, the skin care product is toning lotion, essence, shampoo or hair conditioner.
The skin care composition can restore the grains of the scalp, enables the scalp to present the fine and net-shaped grains which are arranged regularly, can improve the moisture content of the skin, and has a certain relieving effect on the condition that the scalp is reddened.
Examples
The invention is described generally and/or specifically for the materials used in the tests and the test methods, in the following examples,% means wt%, i.e. percent by weight, unless otherwise specified. The reagents or instruments used are not indicated by manufacturers, and are all conventional reagent products commercially available, wherein the raw materials used in the examples are shown in Table 1.
TABLE 1 sources of the principal raw materials
| Name of raw materials | Type or purity | Manufacturer of the product |
| High molecular weight sodium hyaluronate | ≥95％ | BLOOMAGE BIOTECH Co.,Ltd. |
| Low molecular weight sodium hyaluronate | ≥95％ | BLOOMAGE BIOTECH Co.,Ltd. |
| Ectoin | ≥95％ | BLOOMAGE BIOTECH Co.,Ltd. |
| Glycyrrhizic acid dipotassium salt | ≥98％ | GANSU FANZHI PHARMACEUTICAL Co.,Ltd. |
Example 1
Formulating a skin care composition comprising a humectant: sodium hyaluronate (180wDa) 0.001%, soothing agent: 20% of dipotassium glycyrrhizinate; the solvent is water, and the specific content is shown in table 1.
Examples 2 to 13
Examples 2-13 differ from example 1 in the type and amount of moisturizer and soothing agent added, as shown in table 1.
Comparative example 1
Comparative example 1 differs from example 8 in that it does not contain a humectant, as shown in table 1.
Comparative example 2
Comparative example 2 differs from example 8 in that it does not contain a soothing agent, as shown in Table 1.
TABLE 2 dosage table of various components
Test example 1 moisturizing effect test
Selecting 75 volunteers, and randomly dividing into 15 groups; age: 20-60 years old; the specified antidandruff shampoo was used uniformly during the test period, and 10 ml/time and 1/day of the composition prepared in examples 1 to 13 and comparative examples 1 to 2 were applied to the whole scalp, and clinical index observations were made on days D0, D14, D28, D56 and D84, respectively, and shaving and testing the TEWL value index and the percentage of moisture loss of the scalp were performed on a fixed area, and the test results were averaged, and the results are shown in table 3.
Testing an instrument: CK Cornemeter CM825, Finland Delfin Vapormeter, Germany
TABLE 3 Experimental data
As can be seen from table 3, the TEWL values of the compositions prepared in the examples are decreased by a smaller percentage than the comparative examples, and the moisture content is increased by a larger percentage than the comparative examples, which indicates that the moisturizing agent has a certain moisturizing effect, but the moisturizing effect on the scalp is limited, and the moisturizing effect can be significantly improved after the composition is combined with the soothing agent, wherein the moisturizing effects of the examples 6 to 8 are most obvious, and the moisturizing effect is the best after the composition of hyaluronic acid and the specific soothing agent with certain molecular weight is combined.
Test example 2 scalp redness test
Selecting 75 volunteers with reddish scalp; age: 20-65 years old; the specified antidandruff agent-free shampoo was used uniformly during the test period, and the compositions prepared in examples 1 to 13 and comparative examples 1 to 2 were applied to the whole scalp 10 ml/time and 1 time/day for clinical index observation on days D0, D14, D28, D56 and D84, respectively, and the reddening condition of the scalp was observed by taking a photograph using a scalp skin mirror, the results of which are shown in Table 4, wherein
Severe redness: visible with naked eyes, the capillaries are obviously thicker or more in number and are hooked into a sheet;
moderate redness: visible with naked eyes, the capillaries are obvious, but thinner or less in quantity and scattered in distribution;
slight reddening: skin tone is near normal or slightly red, and capillaries are barely visible to the naked eye;
no blushing: normal skin color, no visible capillaries to the naked eye.
Testing an instrument: taiwan CBS scalp dermatoscope
TABLE 4 Experimental data
As can be seen from Table 4, the scalp redness was reduced for 28 days using the compositions prepared in examples 1 to 13, the scalp redness disappeared after 84 days, the comparative example reduced the scalp redness only, and the redness disappeared within 84 days could not be eliminated.
Test example 3 scalp texture test
30 volunteers whose scalp texture had disappeared were selected and tried with the compositions prepared in examples 1 to 13 and comparative examples 1 to 2, respectively, and the designated antidandruff shampoo was uniformly used during the test, and the compositions of examples 1 to 13 and comparative examples 1 to 2 were applied to the entire scalp 10 ml/time, 1 time/day, and clinical index observations were made on days D0, D14, D28, D56 and D84, respectively, and were shaved in a fixed area and photographed with a skin mirror.
Testing an instrument: taiwan CBS scalp dermatoscope
Experimental data as shown in table 5, fig. 1 is a schematic representation of the change in skin texture after the use of the skin care composition described in example 8, wherein,
invisible: the texture is not visible
Blurring: the texture is scattered, and the skin-print impression and pore recession are shallow;
clear: the pores are obviously recessed, the dermatoglyph texture is clear, and the pores are taken as the center to present a regular radial shape;
the arrangement is neat: the pores are obviously recessed, the dermatoglyph grains are clear, and the pores are regularly and radially arranged by taking the pores as the center.
TABLE 5 Experimental data
As can be seen from table 5, the use of the compositions described in examples 1 to 13 restored the scalp texture and caused the scalp to exhibit fine, net-like, well-aligned texture, while the use of the compositions described in comparative examples revealed that the skin texture was not visible or obscured, indicating that the skin care compositions provided by the present invention restored the scalp texture and caused the scalp to exhibit fine, net-like, well-aligned texture.
In conclusion, the skin care composition provided by the invention can restore the grains of the scalp, so that the scalp presents fine and net-like grains with orderly arrangement. In addition, the skin care composition provided by the application can also improve the moisture content of the skin and has a certain relieving effect on the condition of red scalp.
The foregoing is directed to preferred embodiments of the present invention, other and further embodiments of the invention may be devised without departing from the basic scope thereof, and the scope thereof is determined by the claims that follow. However, any simple modification, equivalent change and modification of the above embodiments according to the technical essence of the present invention are within the protection scope of the technical solution of the present invention.
Claims (10)
1. A skin care composition comprising a moisturizing agent and a soothing agent.
2. The skin care composition according to claim 1, wherein the moisturizer is present in an amount of 0.001 to 20%, preferably 0.1 to 5%, further 0.1 to 0.5% by mass of the skin care composition;
the content of the soothing agent is 0.001-20%, preferably 0.1-5%, and more preferably 0.1-0.5%.
3. The composition according to claim 1 or 2, wherein the humectant is a biomacromolecule polysaccharide, preferably the biomacromolecule polysaccharide is selected from hyaluronic acid or a salt thereof, cellulose and a derivative thereof, guar gum, trehalose, rhamnose or biosaccharide gum, more preferably hyaluronic acid or a salt thereof.
4. The composition according to claim 3, wherein the molecular weight of the hyaluronic acid or salt thereof is 0.5w-180wDa, preferably 0.5w-150wDa, more preferably 1w-130 wDa.
5. The skin care composition according to claim 3 or 4, wherein the hyaluronic acid or salt thereof comprises high molecular weight hyaluronic acid or salt thereof and low molecular weight hyaluronic acid or salt thereof, preferably, the mass ratio of the high molecular weight hyaluronic acid or salt thereof to the low molecular weight hyaluronic acid or salt thereof is 1:0.1-10, preferably 1:0.5-5, and more preferably 1: 1-3.
6. The skin care composition according to claim 5, wherein the high molecular weight hyaluronic acid or salt thereof has a molecular weight of 110w-180wDa, preferably 110w-150wDa, further preferably 110w-130 wDa;
the molecular weight of the low molecular weight hyaluronic acid or the salt thereof is 0.5w-50wDa, preferably 0.5w-30wDa, and more preferably 0.5w-1 wDa.
7. The skin care composition according to any one of claims 1 to 6, wherein the soothing agent is selected from one or more of dipotassium glycyrrhizinate, carboxymethyl chitin, carboxymethyl chitosan, ectoin, comfrey extract, chamomile extract and citrus fruit extract, preferably dipotassium glycyrrhizinate and ectoin.
8. A skin care product comprising the skin care composition according to any one of claims 1 to 7 and an adjuvant, preferably the skin care composition is 1 to 100%, preferably 30 to 60% by mass of the skin care product.
9. A method for enhancing skin care by topically applying the skin care product of claim 8 to the skin of a patient.
10. Use of a skin care composition according to any one of claims 1 to 7 in the field of skin care products, preferably lotions, serums, shampoos or conditioners.
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| CN113368300A (en) * | 2021-05-31 | 2021-09-10 | 绽妍生物科技有限公司 | EPS and mussel extract compounded dressing for repairing skin barrier and preparation method thereof |
| CN114272150A (en) * | 2021-12-24 | 2022-04-05 | 诺斯贝尔化妆品股份有限公司 | Cutin stripping composition for cutin layer tissue and cutin stripping product |
| CN115607502A (en) * | 2022-12-19 | 2023-01-17 | 广州集妍化妆品科技有限公司 | Composition containing sweet osmanthus extract and application and cosmetic thereof |
| CN116236425A (en) * | 2021-12-07 | 2023-06-09 | 华熙生物科技股份有限公司 | Composition for scalp care after hair implantation, preparation method and application thereof |
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| CN113368300A (en) * | 2021-05-31 | 2021-09-10 | 绽妍生物科技有限公司 | EPS and mussel extract compounded dressing for repairing skin barrier and preparation method thereof |
| CN116236425A (en) * | 2021-12-07 | 2023-06-09 | 华熙生物科技股份有限公司 | Composition for scalp care after hair implantation, preparation method and application thereof |
| CN114272150A (en) * | 2021-12-24 | 2022-04-05 | 诺斯贝尔化妆品股份有限公司 | Cutin stripping composition for cutin layer tissue and cutin stripping product |
| CN115607502A (en) * | 2022-12-19 | 2023-01-17 | 广州集妍化妆品科技有限公司 | Composition containing sweet osmanthus extract and application and cosmetic thereof |
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