CN112540170A - Immunoassay analyzer and analysis method - Google Patents

Immunoassay analyzer and analysis method Download PDF

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Publication number
CN112540170A
CN112540170A CN201910893242.0A CN201910893242A CN112540170A CN 112540170 A CN112540170 A CN 112540170A CN 201910893242 A CN201910893242 A CN 201910893242A CN 112540170 A CN112540170 A CN 112540170A
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reagent card
card
bearing frame
bottom plate
reagent
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CN112540170B (en
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高雪红
何太云
于怀博
陈建平
张震
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Shenzhen Increcare Biotech Co Ltd
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Shenzhen Increcare Biotech Co Ltd
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/5302Apparatus specially adapted for immunological test procedures

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  • Urology & Nephrology (AREA)
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  • Automatic Analysis And Handling Materials Therefor (AREA)

Abstract

The invention relates to an immunoassay analyzer and a method thereof. The immunoassay analyzer comprises: the bearing mechanism comprises a support, a driving assembly and a bearing frame for bearing the reagent card, wherein the driving assembly is arranged on the support and connected with the bearing frame; the photometric mechanism is arranged on the support and used for collecting optical signals on the reagent card, and the driving assembly drives the bearing frame to move; the card detection mechanism is connected with the support and is used for detecting whether a reagent card exists on the bearing frame; and the scanning mechanism is connected with the support and is used for acquiring the graphic code on the reagent card. When the card detecting mechanism detects that the reagent card exists on the bearing frame, the scanning mechanism automatically scans the graphic code on the reagent card, the driving assembly automatically enables the reagent card to be close to the light measuring mechanism to move, the light measuring mechanism collects light signals of the reagent card, and the whole detection process saves manual operation in each link, so that the detection efficiency is improved.

Description

Immunoassay analyzer and analysis method
Technical Field
The invention relates to the technical field of in-vitro diagnosis, in particular to an immunoassay analyzer and an immunoassay method.
Background
The immunoassay analyzer detects reactants on a reagent card by analyzing optical signals, and the conventional immunoassay analyzer can pull out the current reagent card and insert the next reagent card for detection after a test result is output after a test sample on the reagent card is tested when the reagent card is inserted every time, so that the detection efficiency is low. Moreover, the traditional immunoassay analyzer needs to manually input the information on the reagent card into the immunoassay analyzer, and many links in the detection all need to be manually operated, for example, each test needs to click a start button on an operation interface to enter a detection process, which undoubtedly affects the detection efficiency of the immunoassay analyzer. Some existing immunoassay analyzers can scan a reagent card bar code through a bar code scanner to obtain detection data, but once the bar code scanner fails or the bar code is damaged, the risk of incapability of detection is caused, and further the waste of the reagent card and a sample reagent is caused.
Disclosure of Invention
The invention solves the technical problem of improving the detection efficiency of the immunoassay analyzer.
An immunoassay analyzer for detecting a reagent card, comprising:
the bearing mechanism comprises a support, a driving assembly and a bearing frame for bearing the reagent card, wherein the driving assembly is arranged on the support and connected with the bearing frame;
the photometric mechanism is arranged on the support and used for collecting optical signals on the reagent card, and the driving assembly drives the bearing frame to move away from or close to the photometric mechanism relative to the support;
the card detection mechanism is connected with the support and is used for detecting whether a reagent card exists on the bearing frame; and
and the scanning mechanism is connected with the support and is used for acquiring the graphic code on the reagent card.
In one embodiment, the bearing frame comprises a bottom plate, side plates and flanges, the side plates are arranged around the edge of the bottom plate, the bottom plate and the side plates jointly enclose a containing groove for containing the reagent card, and the flanges are connected with the end parts of the side plates far away from the bottom plate; when the reagent card is positioned in the accommodating groove, the reagent card is clamped between the retaining edge and the bottom plate.
In one embodiment, the bearing frame further comprises an elastic part, the elastic part comprises a fixing part and a top supporting part, a counter bore communicated with the accommodating groove is formed in the bottom plate, the fixing part is fixed in the counter bore, and the top supporting part is elastically connected with the fixing part and suspended above the bottom plate.
In one embodiment, the bottom plate is provided with a through hole penetrating through the bottom plate and communicating with the accommodating groove, and when a reagent card inserted in place exists in the accommodating groove, the reagent card covers the through hole to prevent light emitted by the card detecting mechanism from passing through the through hole.
In one embodiment, the end of the bottom plate is further provided with a position avoiding opening communicated with the accommodating groove, and when a reagent card exists in the accommodating groove, the part of the reagent card corresponding to the position avoiding opening is exposed out of the accommodating groove.
In one embodiment, the card checking mechanism comprises a light-emitting part and a sensing part which are oppositely arranged, and the light-emitting part and the sensing part are arranged on two opposite sides of the bearing frame; when the reagent card is not arranged on the bearing frame, the light generated by the light-emitting part can pass through the bearing frame and be received by the sensing part.
In one embodiment, the photometric mechanism includes a fixing frame and an optical assembly for collecting optical signals on the reagent card, the fixing frame is provided with a waist-shaped hole, and the optical assembly is provided with a round hole corresponding to the waist-shaped hole.
In one embodiment, the method further comprises at least one of the following steps:
the graphic code comprises a one-dimensional code and a two-dimensional code;
the driving assembly comprises a motor, a guide rail and a sliding block, the guide rail is fixed on the support, the sliding block is arranged on the guide rod in a sliding mode and connected with the bearing frame, and an output shaft of the motor is connected with the sliding block.
An immunoassay method for detecting a reagent card, comprising the steps of:
placing a reagent card on the bearing frame;
under the condition that the card checking mechanism senses that the reagent card is placed in place on the bearing frame, a scanning mechanism is adopted to automatically scan the graphic code on the reagent card, and when the scanning mechanism cannot work, information on the reagent card is manually input; and
the bearing frame is driven by the driving assembly to bear the reagent card and move to the accessory of the photometric mechanism, and the photometric mechanism collects optical signals on the reagent card.
In one embodiment, after the optical signal on the reagent card is collected, the driving assembly drives the carrier to carry the reagent card away from the photometric mechanism, unloads the reagent card with the collected optical signal from the carrier, and then directly puts a new reagent card to be detected on the carrier.
One technical effect of one embodiment of the invention is that: by arranging the card checking mechanism, when the card checking mechanism detects that the reagent card exists on the bearing frame, the scanning mechanism automatically scans the graphic code on the reagent card and records information. After the scanning of the scanning mechanism is finished, the driving assembly is automatically started to enable the reagent card to move close to the photometric mechanism along with the bearing frame, and the photometric mechanism automatically carries out optical signal acquisition on the reagent card so as to carry out qualitative or quantitative detection. After the reagent card is detected, the driving assembly is automatically started to enable the reagent card to move away from the photometric mechanism along with the bearing frame, so that the reagent card can be unloaded conveniently. Meanwhile, the next new reagent card to be detected can be tested without waiting for the output of the detection result, so that the manual operation in each link is omitted in the whole detection process, the waiting time of the detection result is also omitted, and the detection efficiency of the whole immunoassay analyzer is improved.
Drawings
Fig. 1 is a schematic perspective view of an immunoassay analyzer according to an embodiment;
FIG. 2 is a schematic view of a portion of the structure of FIG. 1;
FIG. 3 is a schematic view of the structure of FIG. 2 from another perspective;
FIG. 4 is a schematic view of a portion of the structure of FIG. 2;
FIG. 5 is a schematic view of a portion of the structure of FIG. 4 including a card detection mechanism and a carrier;
FIG. 6 is a schematic front view of the structure of FIG. 5;
FIG. 7 is a schematic view of the construction of the loading ledge of FIG. 5;
FIG. 8 is a first exemplary flow diagram of an immunoassay method provided by an embodiment;
fig. 9 is a second exemplary flowchart of an immunoassay method according to an embodiment.
Detailed Description
To facilitate an understanding of the invention, the invention will now be described more fully with reference to the accompanying drawings. Preferred embodiments of the present invention are shown in the drawings. This invention may, however, be embodied in many different forms and should not be construed as limited to the embodiments set forth herein. Rather, these embodiments are provided so that this disclosure will be thorough and complete.
It will be understood that when an element is referred to as being "secured to" another element, it can be directly on the other element or intervening elements may also be present. When an element is referred to as being "connected" to another element, it can be directly connected to the other element or intervening elements may also be present. The terms "inner", "outer", "left", "right" and the like as used herein are for illustrative purposes only and do not represent the only embodiments.
Referring to fig. 1 to 4, the present invention provides an immunoassay analyzer 10 for detecting a reagent card 20 by collecting optical signals of reactants in the reagent card 20 to perform quantitative or qualitative analysis on the reactants. The reagent cards 20 are provided with graphic codes such as one-dimensional codes or two-dimensional codes, and information on the test items, test batches, sample types and the like of each reagent card 20 is recorded on the graphic codes. The immunoassay analyzer 10 includes a carrying mechanism 100, a card detecting mechanism 200, a scanning mechanism 300, and a photometry mechanism 400.
Referring to fig. 2 to 4, in some embodiments, the supporting mechanism 100 includes a support 110, a carrier 120, and a driving assembly 130, the driving assembly 130 is disposed on the support 110 and connected to the carrier 120, and the driving assembly 130 can drive the carrier 120 to move away from or close to the photometric mechanism 400 relative to the support 110. The driving assembly 130 includes a motor 131, a guide rail 132 and a slider 133, the motor 131 may be a lead screw motor, that is, the output shaft 131a of the motor 131 makes a linear motion, although the lead screw motor 131 may also be replaced by an air cylinder. The guide rail 132 is fixed on the support 110, the guide rail 132 is a linear guide rail 132, the slide block 133 is slidably disposed on the guide rail 132, and the carriage 120 is disposed on the slide block 133. When the output shaft 131a of the motor 131 makes a linear motion, the motor 131 can drive the slider 133 to slide on the guide rail 132 in a reciprocating manner, so that the carriage 120 moves close to or away from the photometric mechanism 400.
Referring to fig. 4 to 7, the loading frame 120 may include a bottom plate 121, a side plate 122, a rib 123 and a resilient member 127. The bottom plate 121 is substantially rectangular and horizontally disposed, and the side plate 122 surrounds the bottom plate 121 and is vertically disposed, for example, the side plate 122 is connected to three edges of the bottom plate 121, so that the bottom plate 121 and the side plate 122 together enclose a containing groove 125, and the containing groove 125 is used for containing the reagent card 20, so as to realize a carrying function of the reagent card 20 by the carrier 120. One end (lower end) of the side plate 122 is connected to the bottom plate 121, and the other end (upper end) of the side plate 122 is a free end, which is obviously disposed away from the bottom plate 121. The flanges 123 are horizontally arranged, and one end of each flange 123 is connected with the upper end of the side plate 122, so that the flanges 123 are suspended above the accommodating groove 125, the number of the flanges 123 can be two, and the two flanges 123 are arranged just oppositely. The elastic member 127 is disposed on the bottom plate 121 and disposed in the receiving groove 125, when the reagent card 20 is received in the receiving groove 125, the elastic member 127 applies a pressing force to the reagent card 20 toward the rib 123 (upward), so that the reagent card 20 is sandwiched between the rib 123 and the bottom plate 121, and the stability of the reagent card 20 is ensured, and by providing the elastic member 127, the carrier 120 can be adapted to reagent cards 20 with different thickness dimensions. Meanwhile, the side surface of the reagent card 20 accommodated in the accommodating groove 125 abuts against the inner surface of the side plate 122, that is, the side plate 122 forms a limiting function for the reagent card 20. Therefore, the reagent card 20 can be effectively prevented from shaking in the accommodating groove 125 by the combined action of the elastic member 127 and the side plate 122.
The elastic element 127 comprises a fixed part 127a and a top supporting part 127b, the fixed part 127a is a flat sheet structure, the top supporting part 127b is a bent sheet structure, the top supporting part 127b is elastically connected with the fixed part 127a, and a certain angle is formed between the fixed part 127a and the top supporting part 127 b. The bottom plate 121 is provided with a counter bore 124, the counter bore 124 can be regarded as a part of the bottom wall of the receiving groove 125 which is formed by sinking, the fixing part 127a can be installed in the counter bore 124 by a fixing method such as screwing or gluing, when the fixing part 127a is installed and received in the counter bore 124, the upper surface of the fixing part 127a can be flush with the surface of the bottom plate 121, meanwhile, the top supporting part 127b is suspended above the bottom plate 121 without contacting the bottom plate 121, namely, a certain distance is kept between the top supporting part 127b and the bottom plate 121. When the reagent card 20 is placed in the receiving groove 125, an interaction force is generated between the reagent card 20 and the top portion 127b, so that the top portion 127b stores energy.
The bottom plate 121 is formed with a through hole 128, the through hole 128 penetrates through the upper surface and the lower surface of the bottom plate 121, and obviously, the through hole 128 is communicated with the containing groove 125. When the reagent card 20 is inserted into the receiving groove 125, the reagent card 20 covers the through hole 128 to form a blocking effect, so that the light emitted from the card detecting mechanism 200 cannot pass through the through hole 128. On the contrary, when the reagent card 20 does not exist in the accommodating groove 125 or the reagent card 20 is not inserted in place, the through hole 128 is not blocked, so that the light emitted by the card detecting mechanism 200 can pass through the through hole 128.
The end of the bottom plate 121 is further provided with a position avoiding opening 126, and the position avoiding opening 126 is communicated with the accommodating groove 125. When the reagent card 20 is present in the accommodating groove 125, a portion of the reagent card 20 corresponding to the avoiding opening 126 is exposed from the accommodating groove 125. When the reagent card 20 needs to be taken out from the accommodating groove 125, the part of the reagent card 20 exposed out of the accommodating groove 125 is conveniently directly held by hands to apply a force, so that the applied card is smoothly separated from the accommodating groove 125. In short, the access opening 126 is provided to facilitate the application of force to the reagent cards 20, thereby facilitating the rapid loading and unloading of the reagent cards 20 from the carrier 120.
In some embodiments, the card checking mechanism 200 includes a mounting block 210 and a photoelectric sensor 220, the photoelectric sensor 220 is fixed on the mounting block 210, the mounting block 210 is fixed on the support 110, the mounting block 210 includes a first mounting portion 211 and a second mounting portion 212 which are connected together by a connecting member and are oppositely arranged, both the first mounting portion 211 and the second mounting portion 212 are substantially flat-plate-shaped and are horizontally arranged, the first mounting portion 211 and the second mounting portion 212 are respectively disposed at two opposite sides of the carrier 120, for example, the first mounting portion 211 is located above the carrier 120, and the second mounting portion 212 is located below the carrier 120. The photoelectric sensor 220 includes a light emitting portion 221 and a sensing portion 222, the light emitting portion 221 can be fixed on the first mounting portion 211, the sensing portion 222 can be fixed on the second mounting portion 212, since the first mounting portion 211 and the second mounting portion 212 are respectively located above and below the carrier 120, at this time, the light emitting portion 221 is also located above the carrier 120, the sensing portion 222 is located below the carrier 120, and at the same time, both the light emitting portion 221 and the sensing portion 222 correspond to the through hole 128 on the bottom plate 121.
When the reagent card 20 is not present in the accommodating groove 125 or the reagent card 20 is not inserted in place, the light emitted from the light emitting portion 221 above the bottom plate 121 can pass through the through hole 128 to the lower side of the bottom plate 121 to be received by the sensing portion 222, and at this time, the photoelectric sensor 220 will emit a signal that the reagent card 20 is not detected in the carrier 120. When the reagent card 20 is present in the accommodating groove 125, since the reagent card 20 covers the through hole 128 to form a blocking effect, the light emitted from the upper side of the bottom plate 121 by the light emitting portion 221 cannot pass through the through hole 128 to the lower side of the bottom plate 121 and is received by the sensing portion 222, and at this time, the photoelectric sensor 220 will emit a signal that the presence of the reagent card 20 in the carrier 120 is detected. When the photoelectric sensor 220 signals the presence of the reagent card 20 in the carrier 120, the scanning mechanism 300 will automatically scan the graphic code on the reagent card 20 to record information about the test items, test batches, and sample types on the reagent card 20.
Referring to fig. 2 to 4, in some embodiments, the light measuring mechanism 400 includes a fixing frame 410 and an optical assembly 420, the optical assembly 420 collects optical signals in the reactant on the reagent card 20 so as to perform qualitative or quantitative tests on the reactant, a lower end of the fixing frame 410 is fixed on the support 110, and the optical assembly 420 is mounted at an upper end of the fixing frame 410 so that the optical assembly 420 is located right above the guide rail 132, and when the motor 131 drives the slider 133 to move, the slider 133 can drive the bearing frame 120 bearing the reagent card 20 to move below the optical assembly 420 so that the optical assembly 420 collects the optical signals. Waist-shaped hole 411 is formed in fixing frame 410, waist-shaped hole 411 extends along the vertical direction, round hole 423 is formed in optical assembly 420, and fasteners such as bolts can be penetrated through waist-shaped hole 411 and round hole 423, so that optical assembly 420 can be detachably mounted on fixing frame 410. By changing the installation position of the fastener relative to the slotted hole 411, the installation position of the optical assembly 420 on the fixing frame 410 can be changed, so that the installation height of the optical assembly 420 relative to the guide rail 132 can be adjusted, and the optical path distance of the light emitted by the optical assembly 420 to the reagent card 20 can be adjusted. The optical assembly 420 may include a light source 421 and a collection module 422, wherein the light emitted from the light source 421 can excite the reactant on the reagent card 20 to generate fluorescence, and the collection module 422 can receive the fluorescence signal generated from the reactant, so that the entire photometric mechanism 400 can perform qualitative or quantitative test on the reactant according to the fluorescence signal.
The working principle of the immunoassay analyzer 10 is described below: the position where the carriage 120 is positioned to load and unload the reagent card 20 is referred to as an initial position 11, and the position where the carriage 120 is positioned below the photometric mechanism 400 to detect the reagent card 20 is referred to as a detection position 12. First, the reagent card 20 to be detected is placed in the receiving groove 125 of the carrier 120, at this time, the light emitted from the light emitting portion 221 of the photoelectric sensor 220 cannot pass through the through hole 128 of the bottom plate 121 and is received by the sensing portion 222, and the photoelectric sensor 220 sends a signal that the reagent card 20 in the carrier 120 is detected. Then, based on the signal from the photo sensor 220, the scanning mechanism 300 will scan the graphic code on the reagent card 20 to record the information on the test item, the test lot and the sample type on the reagent card 20. Of course, in the event of a failure of the scanning mechanism 300, the information on the reagent card 20 may be recorded manually, thereby improving the ability of the immunoassay analyzer 10 to withstand failure. Then, when the information obtained by the scanning mechanism 300 is complete, the motor 131 is automatically turned on to drive the slider 133 to move, the slider 133 drives the carrier 120 carrying the reagent card 20 to be detected to move from the initial station 11 to the detection station 12, the light source 421 of the light measuring mechanism 400 emits light to excite the reagent on the reagent card 20 to generate fluorescence, and the collecting module 422 receives a fluorescence signal generated by the reagent, so that the whole light measuring mechanism 400 performs qualitative or quantitative test on the reagent according to the fluorescence signal. Finally, after the testing of the reagent card 20 by the photometric mechanism 400 is completed, the motor 131 is automatically turned on again to drive the slider 133 to move, the slider 133 drives the carrier 120 carrying the tested reagent card 20 to move from the testing station 12 to the initial station 11, and finally the tested reagent card 20 is unloaded from the carrier 120 at the initial station 11, so that a new reagent card 20 to be tested is put on the carrier 120 for the next testing.
By providing the card checking mechanism 200, when the card checking mechanism 200 detects the presence of the reagent card 20 on the carrier 120, the scanning mechanism 300 will automatically scan the graphic code on the reagent card 20 to record the relevant detection information. When the scanning mechanism 300 finishes scanning, the motor 131 is automatically turned on to move the reagent card 20 from the initial station 11 to the detection station 12 along with the carrier 120, and the photometric mechanism 400 automatically performs optical signal collection on the reagent card 20 for qualitative or quantitative testing. When the reagent card 20 is tested, the motor 131 will automatically be turned on to move the reagent card 20 from the testing station 12 to the home station 11 following the carriage 120 for unloading the reagent card 20. Therefore, the whole detection process omits the manual operation of each link, thereby greatly improving the detection efficiency of the immunoassay analyzer 10. Meanwhile, after the reagent card 20 is unloaded after the detection is finished, the detection result can be automatically stored in the memory of the immunoassay analyzer 10, and a new reagent card 20 to be detected can be put on the bearing frame 120 without waiting for the display interface of the immunoassay analyzer 10 to output the detection result of the reagent card 20, so that the effect of improving the detection efficiency can be also achieved by eliminating the waiting time.
Referring to fig. 1 to 4, and fig. 8 and 9, the present invention also provides an immunoassay method for detecting a reagent card 20, which mainly includes the following steps,
s510, in the first step, the reagent card 20 to be tested is placed on the carrier 120 at the initial station 11.
S520, in the second step, when the photoelectric sensor 220 of the card checking mechanism 200 senses the existence of the reagent card 20, the scanning mechanism 300 automatically scans the graphic code on the reagent card 20, so as to record the information on the test items, the test batches, the sample types and the like on the reagent card 20.
And S530, in the third step, the motor 131 of the driving assembly 130 drives the sliding block 133 to move, the sliding block 133 drives the bearing frame 120 bearing the reagent card 20 to be detected to move from the initial station 11 to the detection station 12, and the photometric mechanism 400 excites and collects an optical signal on the reagent card 20, so that qualitative or quantitative test on the reagent card 20 is realized.
And S540, after the optical signal on the reagent card 20 is acquired, that is, after the reagent card 20 is detected, the driving assembly 130 drives the sliding block 133 to move, the sliding block 133 drives the bearing frame 120 bearing the detected reagent card 20 to move from the detection station 12 to the initial station 11, and the detected reagent card 20 is unloaded from the bearing frame 120, so that a new reagent card 20 to be detected can be directly placed on the bearing frame 120 for the next detection without waiting for the display interface of the immunoassay analyzer 10 to output the detection result of the reagent card 20, and meanwhile, a button for starting the detection can be clicked on the operation interface of the immunoassay analyzer 10 to enter the detection flow, so that the aim of improving the detection efficiency can be achieved by eliminating the waiting time.
In some embodiments, when the scanning mechanism 300 in the second step fails to scan the graphic code to record information, the information of the reagent card 20 can be manually input directly from the operation interface of the immunoassay analyzer 10, so that the reagent card 20 can smoothly complete the whole detection process, and the risk resistance of the whole immunoassay method to the failure is improved.
The technical features of the embodiments described above may be arbitrarily combined, and for the sake of brevity, all possible combinations of the technical features in the embodiments described above are not described, but should be considered as being within the scope of the present specification as long as there is no contradiction between the combinations of the technical features.
The above-mentioned embodiments only express several embodiments of the present invention, and the description thereof is more specific and detailed, but not construed as limiting the scope of the invention. It should be noted that, for a person skilled in the art, several variations and modifications can be made without departing from the inventive concept, which falls within the scope of the present invention. Therefore, the protection scope of the present patent shall be subject to the appended claims.

Claims (10)

1. An immunoassay analyzer for detecting a reagent card, comprising:
the bearing mechanism comprises a support, a driving assembly and a bearing frame for bearing the reagent card, wherein the driving assembly is arranged on the support and connected with the bearing frame;
the photometric mechanism is arranged on the support and used for collecting optical signals on the reagent card, and the driving assembly drives the bearing frame to move away from or close to the photometric mechanism relative to the support;
the card detection mechanism is connected with the support and is used for detecting whether a reagent card exists on the bearing frame; and
and the scanning mechanism is connected with the support and is used for acquiring the graphic code on the reagent card.
2. The immunoassay analyzer of claim 1, wherein the carrier comprises a bottom plate, a side plate and a rib, the side plate is disposed around an edge of the bottom plate, the bottom plate and the side plate together define a containing groove for containing the reagent card, and the rib is connected to an end of the side plate away from the bottom plate; when the reagent card is positioned in the accommodating groove, the reagent card is clamped between the retaining edge and the bottom plate.
3. The immunoassay analyzer of claim 2, wherein the supporting frame further comprises an elastic member, the elastic member comprises a fixing portion and a supporting portion, the bottom plate is provided with a counter bore communicated with the accommodating groove, the fixing portion is fixed in the counter bore, and the supporting portion is elastically connected with the fixing portion and suspended above the bottom plate.
4. The immunoassay analyzer of claim 2, wherein the bottom plate is provided with a through hole penetrating through the bottom plate and communicating with the receiving groove, and when a reagent card inserted in place is present in the receiving groove, the reagent card covers the through hole to prevent light emitted by the card detecting mechanism from passing through the through hole.
5. The immunoassay analyzer of claim 2, wherein an avoiding opening communicating with the containing groove is further formed at an end portion of the bottom plate, and when a reagent card exists in the containing groove, a portion of the reagent card corresponding to the avoiding opening is exposed out of the containing groove.
6. The immunoassay analyzer of claim 1, wherein the card detecting mechanism comprises a light emitting portion and a sensing portion disposed oppositely, the light emitting portion and the sensing portion being disposed at opposite sides of the carrier; when the reagent card is not arranged on the bearing frame, the light generated by the light-emitting part can pass through the bearing frame and be received by the sensing part.
7. The immunoassay analyzer of claim 1, wherein the photometric mechanism comprises a fixing frame and an optical assembly for collecting optical signals on the reagent card, wherein the fixing frame is provided with a waist-shaped hole, and the optical assembly is provided with a round hole corresponding to the waist-shaped hole.
8. The immunoassay analyzer of claim 1, further comprising at least one of:
the graphic code comprises a one-dimensional code and a two-dimensional code;
the driving assembly comprises a motor, a guide rail and a sliding block, the guide rail is fixed on the support, the sliding block is arranged on the guide rod in a sliding mode and connected with the bearing frame, and an output shaft of the motor is connected with the sliding block.
9. An immunoassay method for detecting a reagent card, comprising the steps of:
placing a reagent card on the bearing frame;
under the condition that the card checking mechanism senses that the reagent card is placed in place on the bearing frame, a scanning mechanism is adopted to automatically scan the graphic code on the reagent card, and when the scanning mechanism cannot work, information on the reagent card is manually input; and
the bearing frame is driven by the driving assembly to bear the reagent card and move to the position near the photometric mechanism, and the photometric mechanism collects optical signals on the reagent card.
10. The immunoassay method of claim 9, wherein after the optical signal on the reagent card is collected, the driving assembly drives the carrier to carry the reagent card away from the photometric mechanism, unloads the reagent card with the collected optical signal from the carrier, and then directly places a new reagent card to be tested on the carrier.
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CN113533211A (en) * 2021-08-20 2021-10-22 四川新健康成生物股份有限公司 Bar code recognition device and algorithm for fluorescence analyzer
CN113671177A (en) * 2021-08-16 2021-11-19 帝鸿科技(珠海)有限公司 ICT-based handheld colloidal gold chromatography immunoassay analyzer

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