CN112534468A - Ultrasonic elastography device and method for processing elastic image - Google Patents
Ultrasonic elastography device and method for processing elastic image Download PDFInfo
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Abstract
An ultrasonic elastography device and a method for processing an elasticity image, the method comprises the following steps: the credibility of each frame of elastic image is evaluated according to the ultrasonic echo data for generating the elastic image, and prompt information about the credibility of the elastic image is displayed to a user based on an evaluation result so that the user can select based on the credibility or directly output the elastic image which is screened or judged to be high in credibility, so that the situation that the credibility of the elastic image is judged manually is avoided, the working difficulty of the user can be reduced, and the elastic image with high credibility can be obtained.
Description
The invention relates to ultrasonic equipment, in particular to an ultrasonic elastography device and a method for processing an elastic image.
Ultrasound elastography is one of the hot spots concerned by clinical research in recent years, mainly reflects elasticity or hardness of tissues, and is increasingly applied to the aspects of auxiliary detection of tissue cancer lesions, judgment of benign and malignant tissues, prognosis recovery evaluation and the like.
Ultrasound elastography generally includes strain elastography and shear wave elastography.
The strain elasticity imaging method mainly comprises the steps of pressing tissues by a probe to generate certain deformation, calculating strain parameters such as strain quantity and strain rate related to the elasticity of the tissues and imaging, and indirectly reflecting the elasticity difference among different tissues according to the distribution of the strain quantity or strain rate on an elastic image. Since the strain parameters are sensitive to pressure, the pressure applied by the probe in this method needs to be as uniform and stable as possible, which puts high demands on the manipulation of the operator. However, it is difficult to ensure that the pressure meets the requirement in each operation, and therefore, whether the generated elastic image can be used as the basis for diagnosis or not also brings great trouble to doctors.
The shear wave imaging method mainly comprises the steps of emitting pulse waves through a probe, generating shear waves propagating in tissues, detecting propagation parameters (such as propagation speed) of the shear waves, imaging according to the propagation parameters of all parts on a shear wave propagation path, and indirectly reflecting hardness difference between different tissues according to distribution of the propagation parameters (such as propagation speed) of the shear waves on an image. Because the operator does not depend on specific pressure on the tissue, the elastography mode is improved in the aspects of stability and repeatability, and the quantitative measurement result enables diagnosis of doctors to be more convenient and objective, so that the elastography mode is widely concerned and popular by the doctors. However, in the current shear wave elastography technology, because the shear wave in the tissue is very weak and is easily affected by the interference of the patient's breathing, heartbeat, blood vessel pulsation, probe movement and the like, whether the generated elastic image can be used as the basis of diagnosis or not also brings certain troubles to doctors.
Disclosure of Invention
The invention mainly solves the technical problem of providing an ultrasonic elastography device and a method for processing an elastic image, and optimizing the processing of the elastic image.
According to a first aspect, an embodiment provides a method of processing ultrasound elasticity images, comprising:
acquiring ultrasonic echo data of the same region of interest for generating a plurality of frames of elastic images;
evaluating the credibility of each frame of elastic image according to the ultrasonic echo data of the generated elastic image to obtain the credibility evaluation result of the plurality of frames of elastic images;
and prompting the preferred elastic image or determining the preferred elastic image from a plurality of frames of elastic images based on the evaluation result.
According to a second aspect, an embodiment provides a method of processing ultrasound elasticity images, comprising:
acquiring ultrasonic echo data for carrying out ultrasonic detection on a region of interest;
generating an elastic image according to the ultrasonic echo data;
outputting the elastic image to a display for display;
evaluating the credibility of the frame of elastic image according to the ultrasonic echo data of the generated elastic image to obtain a credibility evaluation result of the frame of elastic image;
and displaying the evaluation result and the elastic image in a correlation manner so as to prompt the credibility of the elastic image.
According to a third aspect, an embodiment provides a method of processing ultrasound elasticity images, comprising:
acquiring ultrasonic echo data for carrying out ultrasonic detection on a region of interest;
generating an elastic image according to the ultrasonic echo data;
evaluating the credibility of the frame of elastic image according to the ultrasonic echo data of the generated elastic image to obtain a credibility evaluation result of the frame of elastic image;
and judging whether the evaluation result is qualified, if so, outputting the elastic image to a display for displaying, and otherwise, outputting related prompt information which is unqualified with the elastic image.
According to a fourth aspect, there is provided in an embodiment an ultrasound elastography device comprising:
an ultrasonic probe for emitting ultrasonic waves to a region of interest within a biological tissue and receiving echo signals of the ultrasonic waves;
the transmitting sequence controller is used for generating a transmitting sequence, outputting the transmitting sequence to the ultrasonic probe, and controlling the ultrasonic probe to transmit ultrasonic waves to the region of interest and receive echo signals of the ultrasonic waves;
the data processor is used for acquiring multi-frame ultrasonic echo data of the same region of interest, evaluating the credibility of the elastic image according to the ultrasonic echo data for generating the elastic image to obtain the credibility evaluation result of the multi-frame elastic image, and prompting the preferred elastic image or determining the preferred elastic image from the multi-frame elastic image based on the evaluation result;
and the human-computer interaction equipment comprises a display, and the display is in signal connection with the data processor and is used for displaying the elastic image and/or the evaluation result output by the data processor.
According to a fifth aspect, an embodiment provides an ultrasound elastography device, comprising:
an ultrasonic probe for emitting ultrasonic waves to a region of interest within a biological tissue and receiving echo signals of the ultrasonic waves;
the transmitting sequence controller is used for generating a transmitting sequence, outputting the transmitting sequence to the ultrasonic probe, and controlling the ultrasonic probe to transmit ultrasonic waves to the region of interest and receive echo signals of the ultrasonic waves;
the data processor is used for acquiring ultrasonic echo data for carrying out ultrasonic detection on the region of interest, generating an elastic image according to the ultrasonic echo data and outputting the elastic image to the display for displaying; the data processor is further used for evaluating the credibility of the frame of elastic image according to the ultrasonic echo data for generating the elastic image to obtain a credibility evaluation result of the frame of elastic image, and displaying the evaluation result and the elastic image in a correlation manner to prompt the credibility of the elastic image;
and the human-computer interaction equipment comprises a display, and the display is in signal connection with the data processor and is used for displaying the elastic image and/or the evaluation result output by the data processor.
According to a sixth aspect, there is provided in an embodiment an ultrasound elastography device comprising:
an ultrasonic probe for emitting ultrasonic waves to a region of interest within a biological tissue and receiving echo signals of the ultrasonic waves;
the transmitting sequence controller is used for generating a transmitting sequence, outputting the transmitting sequence to the ultrasonic probe, and controlling the ultrasonic probe to transmit ultrasonic waves to the region of interest and receive echo signals of the ultrasonic waves;
the data processor is used for acquiring ultrasonic echo data for carrying out ultrasonic detection on the region of interest and generating an elastic image according to the ultrasonic echo data; the data processor is further used for evaluating the credibility of the frame of elastic image according to the ultrasonic echo data for generating the elastic image to obtain a credibility evaluation result of the frame of elastic image, judging whether the evaluation result is qualified or not, outputting the elastic image to a display for displaying if the evaluation result is qualified, and otherwise, outputting related prompt information which is not qualified with the elastic image;
and the human-computer interaction equipment comprises a display, and the display is in signal connection with the data processor and is used for displaying the elastic image output by the data processor and/or the related prompt information which is unqualified with the elastic image.
According to a seventh aspect, there is provided in one embodiment an ultrasound elastography device comprising:
an ultrasonic probe for transmitting an ultrasonic wave to a region of interest within a biological tissue and receiving an echo of the ultrasonic wave;
a memory for storing programs and data;
a data processor for implementing the above method by executing the program stored in the memory.
According to an eighth aspect, an embodiment provides a computer-readable storage medium, comprising a program, which is executable by a data processor to implement the above-mentioned method.
According to the embodiment, the credibility of the elastic image frame can be evaluated, prompt information about the credibility of the elastic image can be displayed for a user, so that the user can select the elastic image based on the credibility, and the elastic image which is selected or judged to have high credibility can be directly output, so that the situation that the credibility of the elastic image is judged manually is avoided, the working difficulty of the user can be reduced, and the elastic image with high credibility can be obtained.
FIG. 1 is a schematic structural diagram of an ultrasonic elasticity measurement device in one embodiment;
FIG. 2 is a schematic structural diagram of an ultrasonic elasticity measurement device in one embodiment;
FIG. 3 is a schematic flow chart of a preferred method for ultrasound elastography in one embodiment;
[ amend 26.09.2018 according to rules 91 ] FIGS. 4a and 4b are schematic diagrams of a hinted preferred elasticity image in one embodiment;
correction 26.09.2018 based on rules 91 fig. 5a, 5b are schematic diagrams of a line graph and a histogram showing the evaluation results in one embodiment;
FIG. 6 is a schematic structural diagram of an ultrasonic elasticity measurement device in one embodiment;
FIG. 7 is a schematic flow chart of a preferred method for ultrasound elastography in one embodiment;
FIG. 8 is a schematic structural diagram of an ultrasonic elasticity measurement device in one embodiment;
FIG. 9 is a schematic flow chart of a preferred method for ultrasound elastography in one embodiment.
The present invention will be described in further detail with reference to the following detailed description and accompanying drawings. Wherein like elements in different embodiments are numbered with like associated elements. In the following description, numerous details are set forth in order to provide a better understanding of the present application. However, those skilled in the art will readily recognize that some of the features may be omitted or replaced with other elements, materials, methods in different instances. In some instances, certain operations related to the present application have not been shown or described in detail in order to avoid obscuring the core of the present application from excessive description, and it is not necessary for those skilled in the art to describe these operations in detail, so that they may be fully understood from the description in the specification and the general knowledge in the art.
Furthermore, the features, operations, or characteristics described in the specification may be combined in any suitable manner to form various embodiments. Also, the various steps or actions in the method descriptions may be transposed or transposed in order, as will be apparent to one of ordinary skill in the art. Thus, the various sequences in the specification and drawings are for the purpose of describing certain embodiments only and are not intended to imply a required sequence unless otherwise indicated where such sequence must be followed.
The numbering of the components as such, e.g., "first", "second", etc., is used herein only to distinguish the objects as described, and does not have any sequential or technical meaning. The term "connected" and "coupled" when used in this application, unless otherwise indicated, includes both direct and indirect connections (couplings).
In the embodiment of the invention, when an elastic image of an interested area is generated, multi-frame ultrasonic echo data are collected for the same interested area, reliability evaluation is carried out on each elastic image frame, an evaluation result can be directly output, so that a user can select one or more reliable frames from a plurality of elastic image frames according to the evaluation result, or one or more reliable frames are determined from the plurality of elastic image frames according to the evaluation result and output to the user, or the elastic image synthesized with reliability prompt information is displayed to the user, so that the user can determine whether to adopt the elastic image of the frame based on the reliability. After the preferred elastic image is determined, the preferred elastic image is output to a display, so that a user can perform diagnosis based on the selected credible frame, or perform further analysis processing, such as measuring the hardness value of a focal region, analyzing the color distribution of a focal region and the like, thereby eliminating the subjectivity of the user when the user takes the image or measures the hardness as much as possible, and enabling the diagnosis to be more objective and feasible.
Referring to fig. 1, an ultrasound elasticity measuring apparatus 100 according to an embodiment of the present invention includes an ultrasound probe 101, a transmission sequence controller 102, a transmission and reception circuit 103, an echo signal processor 104, a data processor 105, a display device 106, and a memory 107. The transmitting sequence controller 102 is in signal connection with the ultrasonic probe 101 through the transmitting and receiving circuit 103, the ultrasonic probe 101 is in signal connection with the echo signal processor 104 through the transmitting and receiving circuit 103, the output end of the echo signal processor 104 is connected with the data processor 105, and the output end of the data processor 105 is connected with the display device 106. The memory 107 is connected to the data processor 105.
The ultrasonic probe 101 is used for realizing interconversion between the electric pulse signal and the ultrasonic wave, so as to realize transmission of the ultrasonic wave to the detected biological tissue (for example, the biological tissue in a human body or an animal body) 108 and reception of the ultrasonic echo reflected by the tissue. In this embodiment, the ultrasonic probe 101 includes a plurality of array elements, which are also referred to as ultrasonic transducers, and the plurality of array elements are arranged in a row to form a linear array, or arranged in a two-dimensional matrix to form an area array, and the plurality of array elements may also form a convex array. The array elements are used for transmitting ultrasonic waves according to the excitation electric signals or converting the received ultrasonic waves into electric signals. Each array element is thus operable to transmit ultrasound waves to biological tissue in the region of interest and also to receive ultrasound echoes returned through the tissue. When ultrasonic detection is carried out, which array elements are used for transmitting ultrasonic waves and which array elements are used for receiving the ultrasonic waves can be controlled through a transmitting sequence and a receiving sequence, or the time slots of the array elements are controlled to be used for transmitting the ultrasonic waves or receiving ultrasonic echoes. All array elements participating in ultrasonic wave transmission can be simultaneously excited by the electric signals, so that the ultrasonic waves are transmitted simultaneously; or the array elements participating in the ultrasonic wave transmission can be excited by a plurality of electric signals with certain time intervals, so that the ultrasonic waves with certain time intervals are continuously transmitted.
The transmit sequence controller 102 is configured to generate a transmit sequence and output the transmit sequence to the ultrasound probe, the transmit sequence being configured to control a portion or all of the plurality of array elements to transmit ultrasound waves to biological tissue in the region of interest, the transmit sequence further providing parameters (e.g., amplitude, frequency, number of wave-shots, wave-shot angle, wave pattern, etc.) of the transmitted ultrasound waves.
The transmitting and receiving circuit 103 is connected between the ultrasonic probe and the transmitting sequence controller 102 and the echo signal processor 104, and is configured to transmit the transmitting sequence of the transmitting sequence controller 102 to the ultrasonic probe 101 and transmit the ultrasonic echo signal received by the ultrasonic probe 101 to the echo signal processor 104.
The echo signal processor 104 is configured to process the ultrasonic echo signal, for example, filter, amplify, and beam-synthesize the ultrasonic echo signal, so as to obtain ultrasonic echo data. In a specific embodiment, the echo signal processor 104 may output the ultrasound echo data to the data processor 105, or may store the ultrasound echo data in the memory 107, and when an operation needs to be performed based on the ultrasound echo data, the data processor 105 reads the ultrasound echo data from the memory 107.
The memory 107 is used to store data and programs, which may include system programs for the ultrasound device, various application programs, or algorithms for performing various specific functions.
The data processor 105 is used for acquiring the ultrasonic echo data and obtaining the required parameters or images by adopting a relevant algorithm. For example, the data processor 105 may generate an ultrasound image from the ultrasound echo data, or generate an elasticity image from the ultrasound echo data, with the ultrasound echo data at different times generating different elasticity image frames. In this embodiment, the data processor 105 may further evaluate the reliability of the elastic image according to the ultrasound echo data to obtain a reliability evaluation result of the elastic image of the frame, and determine a preferred elastic image frame based on the evaluation result, or intelligently prompt which frame is the preferred elastic image frame, or directly output the evaluation result of the elastic image of the frame, so that the user can visually check the reliability of the elastic image of the frame, or intelligently output the reliable elastic image. In particular embodiments, the data processor 105 may be a processor chip that executes programs stored in the memory 107 to implement various functions, the data processor 105 may be an FPGA, or the functions may be implemented by discrete components.
The display 106 is used for displaying the elasticity image, the evaluation result and/or various prompting messages output by the data processor, and the content displayed by the display 106 can be expressed by the mode of images, characters, numbers, graphs or diagrams. The display 106 is part of a human-computer interaction device, which may also include input devices such as a keyboard, mouse, trackball, or touch screen.
The invention is illustrated by the following specific examples.
In one embodiment, an intelligent frame selection mode may be designed, and when the mode is performed, a user may be allowed to detect and generate a plurality of frames of elastic images, evaluate the credibility of the plurality of frames of elastic images, and determine a preferred elastic image from the plurality of frames of elastic images based on the evaluation result.
Referring to fig. 2, an ultrasound elasticity measuring apparatus 200 according to an embodiment of the present invention may include an ultrasound probe 201, a transmit sequence controller 202, a transmit and receive circuit 203, an echo signal processor 204, a data processor 205, a display device 206, and a memory 207. The data processor 205 may include an acquisition unit 2051, an elastic image generation unit 2052, an evaluation unit 2053, and a frame selection unit 2054. The acquiring unit 2051 is configured to acquire ultrasonic echo data of the same region of interest, which is used for generating a plurality of frames of elastic images, the elastic image generating unit 2052 is configured to generate an elastic image according to the ultrasonic echo data, and the evaluating unit 2053 is configured to evaluate the reliability of the frame of elastic image according to the ultrasonic echo data for generating the elastic image, so as to obtain a reliability evaluation result of the plurality of frames of elastic images; the frame selection unit 2054 is configured to prompt for a preferred elastic image or determine a preferred elastic image from a plurality of elastic images based on the evaluation result.
The method for optimizing the ultrasonic elasticity image based on the ultrasonic elasticity measuring device of the embodiment is shown in fig. 3, and may include the following steps:
and step 10, entering an intelligent frame selection mode. The user can enter the intelligent frame selection mode through a key on the ultrasonic equipment or an icon on the display screen, in the embodiment, multiple times of ultrasonic echo data are received in the mode, a multi-frame elastic image is generated according to the multiple times of ultrasonic echo data, and the multiple times of ultrasonic echo data and frame data of the multi-frame elastic image are temporarily stored.
And 11, transmitting ultrasonic waves to the region of interest of the detected biological tissue according to the transmitting sequence and receiving echoes of the ultrasonic waves. For example, when the type of the elastic image is a strain elastic image, a user needs to press the biological tissue to be detected through a probe to deform the tissue to a certain degree, transmit ultrasonic waves to the region of interest of the biological tissue to be detected while pressing the tissue, receive echoes of the ultrasonic waves, and obtain echo signals of the ultrasonic waves before and after the tissue is deformed. When the type of the elastic image is a shear wave elastic image, a user generates shear waves in tissues by vibrating the probe or transmitting pulsed ultrasonic waves which push the tissues to displace, then transmits the ultrasonic waves to a path through which the shear waves travel, continuously transmits the ultrasonic waves for a period of time, and simultaneously receives echoes of the ultrasonic waves.
And step 12, processing the echo signal of the ultrasonic wave. For example, the ultrasonic echo signal is subjected to filtering, amplification, beam synthesis, and the like, so as to obtain ultrasonic echo data.
And step 13, generating an elastic image according to the ultrasonic echo data.
And step 14, storing the ultrasonic echo data and the frame data of the elastic image.
And step 15, calculating the reliability evaluation result of the elastic image. And evaluating the credibility of the elastic image according to the ultrasonic echo data of the generated elastic image to obtain the credibility evaluation result of the multi-frame elastic image.
In a specific embodiment, the deformation strength of the frame of elastic image is calculated according to the ultrasonic echo data, and the reliability of the frame of elastic image is evaluated according to the deformation strength. When the type of the elastic image is a strain elastic image, the deformation strength comprises the whole strain amount of one frame of elastic image; when the type of elastic image is a shear wave elastic image, the deformation strength includes a shear wave amplitude.
In another embodiment, the deformation uniformity of the frame of elastic image is calculated according to the ultrasonic echo data, and the reliability of the frame of elastic image is evaluated according to the deformation uniformity. When the type of the elastic image is a strain elastic image, the deformation uniformity refers to the difference of strain quantities of different areas in one frame of elastic image; when the type of elastic image is a shear wave elastic image, the deformation uniformity refers to the shear wave morphology.
In another specific embodiment, the signal quality of the ultrasonic echo data generating the elastic image is detected, and the reliability of the frame of elastic image is evaluated according to the signal quality, wherein the signal quality comprises the signal-to-noise ratio and/or the correlation of the ultrasonic echo signals.
In a preferred embodiment, the type of the elastic image may be automatically determined, and then the reliability evaluation result of the elastic image may be calculated according to the type of the elastic image, which specifically includes the following steps: judging the type of the elastic image; determining at least one applicable evaluation standard according to the type of the elastic image, wherein the evaluation standard is a preset evaluation standard applicable to the type of the elastic image or an evaluation standard determined according to the selection of a user; calculating the evaluation parameters of each elastic image according to the evaluation standard and the ultrasonic echo data based on each frame of generated elastic image; and comparing the evaluation parameters of the elastic image with the evaluation standards to obtain the reliability evaluation result of the elastic image.
When the type of the elastic image is judged to be a strain elastic image, applicable evaluation criteria include:
1) and evaluating according to the magnitude of the whole strain of the elastic image. For the strain elastic image, an operator is required to reach a certain pressure when pressing, and the test result is inaccurate due to too large or too small pressure, so that the generated elastic image is evaluated to be reliable or not by taking the whole strain of the region of interest as an evaluation parameter.
The calculation process of the whole strain amount is as follows: calculating the length change of each local area in the region of interest according to the ultrasonic echo data for generating the elastic image, and calculating the strain amount of the local area according to the length change, wherein the calculation formula of the strain amount is as follows:
ε＝(L1-L0)/L0
wherein epsilon is a strain, L0 is the length of a certain local region in the region of interest before tissue deformation, and L1 is the length of the same local region in the region of interest after tissue deformation.
And then averaging the strain of each local area in the region of interest to obtain the overall strain of the region of interest, wherein each frame of elastic image corresponds to one overall strain. And comparing the whole dependent variable of each frame of elastic image with a preset range, and giving different scores when the dependent variable falls into different ranges. For example, when the normal strain amount is in the range of 0.5% to 1%, the score is 100. When the dependent variable is in the range of 0.1% -0.5%, the score is 50, and when the dependent variable is less than 0.1%, the score is 0. When the strain amount is more than 1%, the score is 0. Of course, the above scoring method is only an example, and actually, the corresponding scores in different ranges can be set according to different corresponding curves. The highest score is also not limited to the setting of 100 points. Such as 1 instead, or the rating is not a score, such as A, B, C, D, etc.
2) Evaluation was made based on the uniformity of the amount of strain in the elastic image. Since the force applied to the tissue by the probe may not be uniform due to the influence of the pressing technique, the strain uniformity is used as an evaluation parameter of reliability in the present embodiment. The most common is left-right non-uniformity, with large pressure and small pressure.
The calculation of the deformation uniformity comprises: calculating each local strain of a frame of elastic image according to the ultrasonic echo data, dividing the frame of elastic image into a left part and a right part, averaging the strain of each local area of the left part and the right part to obtain the overall strain of the left part and the right part, calculating the difference value or score value of the overall strain of the left part and the right part to obtain the difference of the overall strain of the left part and the right part, and obtaining the deformation uniformity.
In other embodiments, the global strain amounts in other two designated local areas can be used for comparison to obtain the deformation uniformity. When the difference exceeds a set threshold, giving a lower score; when the difference is below a set threshold, a higher score is given.
3) And evaluating according to the signal quality of the ultrasonic echo data for generating the elastic image. In this case, the evaluation parameter is a signal quality, which includes the signal-to-noise ratio and/or the correlation of the ultrasound echo signal.
The signal-to-noise ratio refers to the signal-to-noise ratio of the ultrasound echo signal that generates the elasticity image. The larger the signal-to-noise ratio, the higher the evaluation score and the better the quality of the generated elastic image, whereas the smaller the signal-to-noise ratio, the lower the evaluation score and the worse the quality of the generated elastic image.
Correlation refers to the cross-correlation or auto-correlation of the ultrasound echo signals that generate the elasticity image, reflecting the degree of correlation between the two signals. The correlation may be calculated using algorithms such as cross-correlation coefficient, SAD, etc. The greater the correlation, the more accurate the calculation of the strain and therefore the higher the evaluation score, whereas the lower the evaluation score.
When the type of the elastic image is judged to be a shear wave elastic image, applicable evaluation criteria include:
1) evaluation was made based on the magnitude of the amplitude of the shear wave generated. In this case, the evaluation parameter is a shear wave amplitude, and the calculation of the evaluation parameter of the elastic image frame includes: and calculating the displacement of each mass point in the region of interest according to the ultrasonic echo data of the generated elastic image frame data, and finding out the point with the maximum displacement as the amplitude of the shear wave. The larger the amplitude of the shear wave is, the less likely the generated shear wave is to be disturbed, and the more accurate the detection result is, so that different scores are set according to the amplitude of the generated shear wave. For example, if the overall amplitude is large, the score is high, and if the overall amplitude is smaller than a preset value, the score is 0.
2) Evaluation was made based on the form of the shear wave. The shear wave morphology includes displacement, velocity and/or acceleration profiles of the individual particles in the region of interest as the shear wave travels. The calculation of the shear wave form parameters comprises: and calculating the displacement of each mass point in the region of interest at different moments according to the ultrasonic echo data of the generated elastic image frame data to obtain a displacement curve of each mass point, deriving the displacement curve with time to obtain a speed curve, and deriving the speed curve with time to obtain an acceleration curve. The curve is smooth, less noise and jumps, giving a higher score.
3) And evaluating according to the signal quality of the ultrasonic echo signal carrying the shear wave propagation information. The signal quality includes a signal-to-noise ratio and/or correlation of the ultrasound echo signals. Different scores are set according to the signal-to-noise ratio of the ultrasonic echo signals carrying the shear wave propagation information, if the signal-to-noise ratio of the echo signals is too low, the scores are low, and if the signal-to-noise ratio is high, the scores are high.
When the evaluation criterion is plural, the reliability score of the elasticity image is a weighted sum of plural scores derived from the plural evaluation criteria.
And step 16, judging whether to finish the detection, wherein the judgment condition can be the preset detection times in the mode, namely, the detection is automatically finished after the preset detection times are reached, and the step 17 is executed. If the condition for ending the detection has not been reached, execution continues with step 11. The condition for judgment may also be an instruction input by the user, for example, the user inputs an instruction to end the detection by a key on the ultrasound apparatus or an icon or a selection item on the display screen.
And step 17, presenting a preferred elastic image based on the evaluation result. In a specific embodiment, the prompting method includes: and synthesizing the multi-frame elastic image data with the respective evaluation results, and outputting and displaying the synthesized images on a display. As shown in fig. 4a, a plurality of thumbnails corresponding to a plurality of frames of elastic images are displayed on a display interface, where a thumbnail may be a reduced image of an elastic image or may be only a box, and a reliability evaluation result of the elastic image is displayed on each thumbnail (for example, in the upper right corner), so that a user can visually check the reliability evaluation result of each frame of elastic image. In another embodiment, as shown in fig. 4b, after the composition, only the elastic image with the best evaluation result may be marked, for example, the elastic image with the best evaluation result is marked, for example, a star mark is made. When displaying the plurality of images after the synthesis, the plurality of images after the synthesis may be tiled, or the plurality of images after the synthesis may be superimposed, or the plurality of images after the synthesis may be sequentially displayed according to a switching instruction of a user.
In another embodiment, the prompting method includes: and generating a visual evaluation statistical chart based on the evaluation results of the plurality of frames of elastic images, and marking one frame or a group of elastic images with the best evaluation results on the evaluation statistical chart. If there are multiple scoring criteria, then different weighting coefficients can be set according to the importance of each scoring criteria, so as to obtain a final score. And according to the difference of the final scores of the frames, finding out a frame with the highest score as the best frame and prompting the best frame to a user. Or may find multiple frames with scores exceeding a certain threshold (e.g., exceeding 80 points) for prompt to the user. For example, a line graph or a histogram is generated by dividing the evaluation result in the order of generation of the plurality of frames of elastic images, and the largest numerical value represents the one frame of elastic image with the best evaluation result, as shown in fig. 5a and 5 b.
In some embodiments, the evaluation result may not be converted into a score, for example, a coordinate corresponding to each frame of the elastic image is established, and the evaluation result of each frame is indicated on the coordinate, for example, the evaluation result is represented by a different color, and the color corresponding to the preferred frame is green, and the other colors are gray. In this way, the user can visually check which frame of elastic image has the best reliability evaluation result.
A preferred elasticity image is determined based on the user's selection, step 18.
And step 19, outputting the preferred elasticity image to a display for displaying, so that a subsequent user performs elasticity analysis on the region of interest according to the preferred elasticity image, for example, strain ratio analysis, focal zone hardness value statistical analysis (such as maximum value, minimum value, mean value, median value, and the like), histogram analysis on focal zone elasticity parameters, and the like according to the preferred elasticity image.
The preferred frame may be one frame or a plurality of frames. The user can select one or more frames of results in the preferred frames according to the prompt results to diagnose. In addition, if the current elasticity measurement result is not credible, the system can also give a warning prompt.
In further embodiments, after step 16, the best elastic image or set of elastic images may be directly found out from the plurality of elastic images as the preferred elastic image based on the evaluation result, and then the preferred elastic image may be output to the display for display.
By the aid of the method and the device, the reliability of the obtained elastic image can be automatically judged, the elastic image with good reliability is prompted to a user or directly output to the user, whether the elastic image is reliable or not does not need to be judged manually, subjective factors in user judgment are avoided, the working difficulty of the user can be reduced, and the elastic image with high reliability can be obtained.
In some embodiments, step 16 may also be omitted, the number of times of detection by the user is not limited, and each frame of elastic image is generated, that is, the reliability of the frame of elastic image is evaluated, and the evaluation result and the elastic image are simultaneously displayed, so that the user can immediately determine whether to use the frame of elastic image as a subsequent diagnosis basis according to the reliability evaluation result of the frame of elastic image.
Referring to fig. 6, an ultrasound elasticity measuring apparatus 300 according to an embodiment of the present invention may include an ultrasound probe 301, a transmit sequence controller 302, a transmit and receive circuit 303, an echo signal processor 304, a data processor 305, a display device 306, and a memory 307. The data processor 305 includes an acquisition unit 3051, an elastic image generation unit 3052, an evaluation unit 3053, and a display unit 3054. The acquiring unit 3051 is configured to acquire ultrasonic echo data for performing ultrasonic detection on the region of interest; the elastic image generation unit 3052 is configured to generate an elastic image from the ultrasound echo data; the evaluation unit 3053 is configured to evaluate the reliability of the frame of elastic image according to the ultrasonic echo data of the generated elastic image, so as to obtain a reliability evaluation result of the frame of elastic image; the display unit 3054 is configured to output the elastic image to a display for display, and display an evaluation result in association with the elastic image to prompt the reliability of the elastic image.
The method for prompting the ultrasound elasticity image based on the ultrasound elasticity measuring apparatus of the present embodiment may be as shown in fig. 7, and includes the following processes:
and 20, transmitting ultrasonic waves to the region of interest of the detected biological tissue according to the transmitting sequence and receiving the echo of the ultrasonic waves.
And step 22, generating an elastic image according to the ultrasonic echo data.
And 24, evaluating the reliability of the elastic image according to the ultrasonic echo data of the generated elastic image to obtain a reliability evaluation result of the elastic image.
And 25, displaying the evaluation result and the elastic image in a correlation manner to prompt the credibility of the elastic image.
The association display includes any one of the following ways:
1) and displaying the evaluation result and the elastic image on the same screen. For example, the evaluation result is displayed in the upper right corner of the elasticity image.
2) And popping up an evaluation result after clicking a preset area on the display interface. For example, the user can click on the elastic image on the display interface, and the evaluation result of the elastic image is popped up after clicking. In another embodiment, a "credibility" icon may also be designed on the display interface, and after the user clicks the "credibility" icon, the evaluation result of the currently displayed elasticity image pops up.
3) And displaying the evaluation result after the cursor moves to a preset area. For example, after the user moves the cursor over the currently displayed elastic image, the evaluation result of the elastic image of the frame pops up near the cursor.
In this embodiment, the displayed evaluation result may be the confidence score of the elastic image, or may be the confidence level, or prompt information indicating that the confidence is qualified or unqualified.
In this embodiment, the timing of steps 23 and 24 may be reversed.
In this embodiment, each time a user generates a frame of elastic image, the user can visually see the reliability evaluation result of the frame of elastic image, so as to determine whether to use the frame of elastic image as a basis for subsequent diagnosis.
Referring to fig. 8, an ultrasound elasticity measuring apparatus 400 according to an embodiment of the present invention may include an ultrasound probe 401, a transmit sequence controller 402, a transmit and receive circuit 403, an echo signal processor 404, a data processor 405, a display device 406, and a memory 407. The data processor 405 includes an acquisition unit 4051, an elastic image generation unit 4052, an evaluation unit 4053, and a determination unit 4054. The acquiring unit 4051 is configured to acquire ultrasonic echo data for performing ultrasonic detection on the region of interest; the elastic image generation unit 4052 is configured to generate an elastic image from the ultrasound echo data; the evaluation unit 4053 is configured to evaluate the reliability of the frame of elastic image according to the ultrasonic echo data of the generated elastic image, so as to obtain a reliability evaluation result of the frame of elastic image; the judging unit 4054 is configured to judge whether the evaluation result is qualified, and if so, notify the elastic image generating unit 4052 to output the elastic image to a display for display, otherwise, the judging unit 4054 outputs prompt information related to the unqualified elastic image.
The method for displaying the ultrasound elasticity image based on the ultrasound elasticity measuring apparatus of the present embodiment may be as shown in fig. 9, and includes the following processes:
and step 30, transmitting ultrasonic waves to the region of interest of the detected biological tissue according to the transmitting sequence and receiving the echo of the ultrasonic waves.
And step 32, generating an elastic image according to the ultrasonic echo data.
And step 33, evaluating the reliability of the frame of elastic image according to the ultrasonic echo data of the generated elastic image to obtain a reliability evaluation result of the frame of elastic image.
And step 34, judging whether the evaluation result is qualified, if so, executing step 35, otherwise, executing step 36.
And step 36, outputting prompt information related to the unqualified elastic image. For example, the user is prompted that the frame of elastic image is not qualified, and the user is asked to test the frame of elastic image again.
In the embodiment, the system automatically judges the reliability of the generated elastic image, and directly presents the elastic image with qualified reliability to the user without manual judgment of the user.
Those skilled in the art will appreciate that all or part of the steps of the various methods in the above embodiments may be implemented by instructions associated with hardware via a program, which may be stored in a computer-readable storage medium, and the storage medium may include: read-only memory, random access memory, magnetic or optical disk, and the like.
Reference is made herein to various exemplary embodiments. However, those skilled in the art will recognize that changes and modifications may be made to the exemplary embodiments without departing from the scope hereof. For example, the various operational steps, as well as the components used to perform the operational steps, may be implemented in differing ways depending upon the particular application or consideration of any number of cost functions associated with operation of the system (e.g., one or more steps may be deleted, modified or incorporated into other steps).
Additionally, as will be appreciated by one skilled in the art, the principles herein may be reflected in a computer program product on a computer readable storage medium, which is pre-loaded with computer readable program code. Any tangible, non-transitory computer-readable storage medium may be used, including magnetic storage devices (hard disks, floppy disks, etc.), optical storage devices (CD-ROMs, DVDs, Blu Ray disks, etc.), flash memory, and/or the like. These computer program instructions may be loaded onto a general purpose computer, special purpose computer, or other programmable data processing apparatus to produce a machine, such that the instructions which execute on the computer or other programmable data processing apparatus create means for implementing the functions specified. These computer program instructions may also be stored in a computer-readable memory that can direct a computer or other programmable data processing apparatus to function in a particular manner, such that the instructions stored in the computer-readable memory produce an article of manufacture including means for implementing the function specified. The computer program instructions may also be loaded onto a computer or other programmable data processing apparatus to cause a series of operational steps to be performed on the computer or other programmable apparatus to produce a computer implemented process such that the instructions which execute on the computer or other programmable apparatus provide steps for implementing the functions specified.
While the principles herein have been illustrated in various embodiments, many modifications of structure, arrangement, proportions, elements, materials, and components particularly adapted to specific environments and operative requirements may be employed without departing from the principles and scope of the present disclosure. The above modifications and other changes or modifications are intended to be included within the scope of this document.
The foregoing detailed description has been described with reference to various embodiments. However, one skilled in the art will recognize that various modifications and changes may be made without departing from the scope of the present disclosure. Accordingly, the disclosure is to be considered in an illustrative and not a restrictive sense, and all such modifications are intended to be included within the scope thereof. Also, advantages, other advantages, and solutions to problems have been described above with regard to various embodiments. However, the benefits, advantages, solutions to problems, and any element(s) that may cause any element(s) to occur or become more pronounced are not to be construed as a critical, required, or essential feature or element of any or all the claims. As used herein, the terms "comprises," "comprising," or any other variation thereof, are intended to cover a non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements does not include only those elements but may include other elements not expressly listed or inherent to such process, method, system, article, or apparatus. Furthermore, the term "coupled," and any other variation thereof, as used herein, refers to a physical connection, an electrical connection, a magnetic connection, an optical connection, a communicative connection, a functional connection, and/or any other connection.
Those skilled in the art will recognize that many changes may be made to the details of the above-described embodiments without departing from the underlying principles of the invention. Accordingly, the scope of the invention should be determined only by the following claims.
Claims (34)
- The processing method for the ultrasonic elastic image is characterized by comprising the following steps:acquiring ultrasonic echo data of the same region of interest for generating a plurality of frames of elastic images;evaluating the credibility of each frame of elastic image according to the ultrasonic echo data of the generated elastic image to obtain the credibility evaluation result of the plurality of frames of elastic images;and prompting the preferred elastic image or determining the preferred elastic image from a plurality of frames of elastic images based on the evaluation result.
- The processing method for the ultrasonic elastic image is characterized by comprising the following steps:acquiring ultrasonic echo data for carrying out ultrasonic detection on a region of interest;generating an elastic image according to the ultrasonic echo data;outputting the elastic image to a display for display;evaluating the credibility of the frame of elastic image according to the ultrasonic echo data of the generated elastic image to obtain a credibility evaluation result of the frame of elastic image;and displaying the evaluation result and the elastic image in a correlation manner so as to prompt the credibility of the elastic image.
- The method according to claim 2, wherein the associating and displaying the evaluation result with the elasticity image includes any one of:displaying the evaluation result and the elastic image on the same screen;popping up an evaluation result after clicking a preset area on a display interface;and displaying the evaluation result after the cursor moves to a preset area.
- The processing method for the ultrasonic elastic image is characterized by comprising the following steps:acquiring ultrasonic echo data for carrying out ultrasonic detection on a region of interest;generating an elastic image according to the ultrasonic echo data;evaluating the credibility of the frame of elastic image according to the ultrasonic echo data of the generated elastic image to obtain a credibility evaluation result of the frame of elastic image;and judging whether the evaluation result is qualified, if so, outputting the elastic image to a display for displaying, and otherwise, outputting related prompt information which is unqualified with the elastic image.
- The method of any one of claims 1-4, wherein the confidence level of the elastic image is evaluated in at least one of the following ways:calculating the deformation intensity of the frame of elastic image according to the ultrasonic echo data, and evaluating the reliability of the frame of elastic image according to the deformation intensity;calculating the deformation uniformity of the frame of elastic image according to the ultrasonic echo data, and evaluating the reliability of the frame of elastic image according to the deformation uniformity;and detecting the signal quality of the ultrasonic echo data for generating the elastic image, and evaluating the reliability of the elastic image of the frame according to the signal quality.
- The method of claim 5, wherein when the type of the elastic image is a strain elastic image, the deformation strength includes an overall strain amount of a frame of the elastic image, and the deformation uniformity refers to a difference in strain amount of different regions in a frame of the elastic image.
- The method of claim 5, wherein when the type of elastic image is a shear wave elastic image, the deformation strength comprises shear wave amplitude and the deformation uniformity comprises shear wave morphology.
- The method of claim 5, wherein the signal quality comprises a signal-to-noise ratio and/or a correlation of an ultrasound echo signal.
- The method of any one of claims 1-4, wherein evaluating the frame of elasticity images for confidence based on ultrasound echo data from which the elasticity images were generated comprises:acquiring the type of the elastic image;determining at least one applicable evaluation standard according to the type of the elastic image, wherein the evaluation standard is a preset evaluation standard applicable to the type of the elastic image, or the evaluation standard is determined according to the selection of a user;calculating the evaluation parameters of each elastic image according to the evaluation standard and the ultrasonic echo data based on each frame of generated elastic image;and comparing the evaluation parameters of the elastic image with the evaluation standards to obtain the reliability evaluation result of the elastic image.
- The method according to claim 9, wherein when the evaluation criterion is plural, the reliability score of the elasticity image is a weighted sum of a plurality of scores derived from the plural evaluation criteria.
- The method of claim 1, wherein determining a preferred elastic image from the plurality of elastic images based on the evaluation results comprises: and finding out one frame or one group with the best evaluation result from the evaluation results of the plurality of elastic images as a preferred elastic image, and outputting the preferred elastic image to a display for displaying.
- The method of claim 1, wherein prompting a preferred elasticity image based on the evaluation result comprises:synthesizing the multi-frame elastic image data with respective evaluation results, and outputting a plurality of synthesized images to a display for displaying; orAnd generating a visual evaluation statistical chart based on the evaluation results of the plurality of frames of elastic images, and marking the elastic image or the group of elastic images with the best evaluation result on the evaluation statistical chart.
- The method of claim 11 or 12, further comprising, after prompting the preferred elastic image, determining the preferred elastic image based on a user selection and outputting the preferred elastic image to a display for display.
- The method of claim 13, further comprising performing an elasticity analysis of a region of interest from the preferred elasticity image.
- The method according to claim 1, further comprising outputting alarm information when the reliability evaluation results of all the elasticity images are not satisfactory.
- An ultrasound elastography device, characterized by comprising:an ultrasonic probe for transmitting an ultrasonic wave to a region of interest within a biological tissue and receiving an echo of the ultrasonic wave;a memory for storing programs and data;a data processor for implementing the method of any one of claims 1-15 by executing a program stored by the memory.
- A computer-readable storage medium, comprising a program executable by a data processor to implement the method of any one of claims 1-15.
- An ultrasound elastography device, characterized by comprising:an ultrasonic probe for emitting ultrasonic waves to a region of interest within a biological tissue and receiving echo signals of the ultrasonic waves;the transmitting sequence controller is used for generating a transmitting sequence, outputting the transmitting sequence to the ultrasonic probe, and controlling the ultrasonic probe to transmit ultrasonic waves to the region of interest and receive echo signals of the ultrasonic waves;the data processor is used for acquiring multi-frame ultrasonic echo data of the same region of interest, evaluating the credibility of the elastic image according to the ultrasonic echo data for generating the elastic image to obtain the credibility evaluation result of the multi-frame elastic image, and prompting the preferred elastic image or determining the preferred elastic image from the multi-frame elastic image based on the evaluation result;and the human-computer interaction equipment comprises a display, and the display is in signal connection with the data processor and is used for displaying the elastic image and/or the evaluation result output by the data processor.
- An ultrasound elastography device, characterized by comprising:an ultrasonic probe for emitting ultrasonic waves to a region of interest within a biological tissue and receiving echo signals of the ultrasonic waves;the transmitting sequence controller is used for generating a transmitting sequence, outputting the transmitting sequence to the ultrasonic probe, and controlling the ultrasonic probe to transmit ultrasonic waves to the region of interest and receive echo signals of the ultrasonic waves;the data processor is used for acquiring ultrasonic echo data for carrying out ultrasonic detection on the region of interest, generating an elastic image according to the ultrasonic echo data and outputting the elastic image to the display for displaying; the data processor is further used for evaluating the credibility of the frame of elastic image according to the ultrasonic echo data for generating the elastic image to obtain a credibility evaluation result of the frame of elastic image, and displaying the evaluation result and the elastic image in a correlation manner to prompt the credibility of the elastic image;and the human-computer interaction equipment comprises a display, and the display is in signal connection with the data processor and is used for displaying the elastic image and/or the evaluation result output by the data processor.
- The apparatus according to claim 19, wherein the display of the evaluation result in association with the elasticity image includes any one of:displaying the evaluation result and the elastic image on the same screen;popping up an evaluation result after clicking a preset area on a display interface;and displaying the evaluation result after the cursor moves to a preset area.
- An ultrasound elastography device, characterized by comprising:an ultrasonic probe for emitting ultrasonic waves to a region of interest within a biological tissue and receiving echo signals of the ultrasonic waves;the transmitting sequence controller is used for generating a transmitting sequence, outputting the transmitting sequence to the ultrasonic probe, and controlling the ultrasonic probe to transmit ultrasonic waves to the region of interest and receive echo signals of the ultrasonic waves;the data processor is used for acquiring ultrasonic echo data for carrying out ultrasonic detection on the region of interest and generating an elastic image according to the ultrasonic echo data; the data processor is further used for evaluating the credibility of the frame of elastic image according to the ultrasonic echo data for generating the elastic image to obtain a credibility evaluation result of the frame of elastic image, judging whether the evaluation result is qualified or not, outputting the elastic image to a display for displaying if the evaluation result is qualified, and otherwise, outputting related prompt information which is not qualified with the elastic image;and the human-computer interaction equipment comprises a display, and the display is in signal connection with the data processor and is used for displaying the elastic image output by the data processor and/or the related prompt information which is unqualified with the elastic image.
- An apparatus according to any one of claims 18 to 21, wherein the data processor is configured to evaluate the trustworthiness of an elasticity image in at least one of:calculating the deformation intensity of the frame of elastic image according to the ultrasonic echo data, and evaluating the reliability of the frame of elastic image according to the deformation intensity;calculating the deformation uniformity of the frame of elastic image according to the ultrasonic echo data, and evaluating the reliability of the frame of elastic image according to the deformation uniformity;and detecting the signal quality of the ultrasonic echo data for generating the elastic image, and evaluating the reliability of the elastic image of the frame according to the signal quality.
- The apparatus of claim 22, wherein when the type of the elastic image is a strain elastic image, the deformation strength includes an overall strain amount of a frame of the elastic image, and the deformation uniformity refers to a difference in strain amount of different regions in a frame of the elastic image.
- The apparatus of claim 22, wherein when the type of elastic image is a shear wave elastic image, the deformation strength comprises shear wave amplitude and the deformation uniformity comprises shear wave morphology.
- The apparatus of claim 22, in which the signal quality comprises a signal-to-noise ratio and/or a correlation of an ultrasound echo signal.
- The apparatus of any one of claims 18-21, wherein the data processor evaluating the confidence level of the frame of the elasticity image from the ultrasound echo data that generated the elasticity image comprises:acquiring the type of the elastic image;determining at least one applicable evaluation standard according to the type of the elastic image, wherein the evaluation standard is a preset evaluation standard applicable to the type of the elastic image, or the evaluation standard is determined according to the selection of a user;calculating the evaluation parameters of each elastic image according to the evaluation standard and the ultrasonic echo data based on each frame of generated elastic image;and comparing the evaluation parameters of the elastic image with the evaluation standards to obtain the reliability evaluation result of the elastic image.
- The apparatus according to claim 26, wherein when the evaluation criterion is plural, the reliability score of the elasticity image is a weighted sum of plural scores derived from the plural evaluation criteria.
- The apparatus of claim 18, wherein the data processor determining a preferred elasticity image from the plurality of elasticity images based on the evaluation results comprises: and finding out one frame or one group with the best evaluation result from the evaluation results of the plurality of elastic images as a preferred elastic image, and outputting the preferred elastic image to a display for displaying.
- The apparatus of claim 18, wherein the data processor prompting the preferred elasticity image based on the evaluation result comprises:synthesizing the multi-frame elastic image data with respective evaluation results, and outputting a plurality of synthesized images to a display for displaying; orAnd generating a visual evaluation statistical chart based on the evaluation results of the plurality of frames of elastic images, and marking one frame or a group of elastic images with the best evaluation results on the evaluation statistical chart.
- The apparatus of claim 28 or 29, further comprising the data processor determining the preferred elastic image based on a user selection after prompting the preferred elastic image, outputting the preferred elastic image to the display for display.
- The apparatus of claim 18, wherein the data processor outputs an alarm message when the reliability evaluation results of all the elasticity images are not satisfactory.
- A system for processing ultrasound elasticity images, comprising:the acquisition unit is used for acquiring ultrasonic echo data of the same region of interest and used for generating multi-frame elastic images;the evaluation unit is used for evaluating the credibility of the elastic image frame according to the ultrasonic echo data of the generated elastic image to obtain the credibility evaluation result of the elastic image frames;and the frame selecting unit is used for prompting the preferred elastic image or determining the preferred elastic image from the plurality of frames of elastic images based on the evaluation result.
- A system for processing ultrasound elasticity images, comprising:the acquisition unit is used for acquiring ultrasonic echo data for carrying out ultrasonic detection on the region of interest;an elastic image generating unit for generating an elastic image from the ultrasonic echo data;the evaluation unit is used for evaluating the credibility of the frame of elastic image according to the ultrasonic echo data for generating the elastic image to obtain a credibility evaluation result of the frame of elastic image;and the display unit is used for outputting the elastic image to a display for displaying, and displaying the evaluation result and the elastic image in a correlation manner so as to prompt the credibility of the elastic image.
- A system for processing ultrasound elasticity images, comprising:the acquisition unit is used for acquiring ultrasonic echo data for carrying out ultrasonic detection on the region of interest;an elastic image generating unit for generating an elastic image from the ultrasonic echo data;the evaluation unit is used for evaluating the credibility of the frame of elastic image according to the ultrasonic echo data for generating the elastic image to obtain a credibility evaluation result of the frame of elastic image;and the judging unit is used for judging whether the evaluation result is qualified or not, outputting the elastic image to a display for displaying if the evaluation result is qualified, and otherwise, outputting related prompt information which is unqualified to the elastic image.
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