CN112526576B - Ophthalmic lens dosimetry device and method - Google Patents

Ophthalmic lens dosimetry device and method Download PDF

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CN112526576B
CN112526576B CN202011348473.2A CN202011348473A CN112526576B CN 112526576 B CN112526576 B CN 112526576B CN 202011348473 A CN202011348473 A CN 202011348473A CN 112526576 B CN112526576 B CN 112526576B
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detector
crystal
energy
radiation particles
particles
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CN112526576A (en
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屈卫卫
杨梦梦
周光明
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Suzhou University
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Suzhou University
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01T—MEASUREMENT OF NUCLEAR OR X-RADIATION
    • G01T1/00—Measuring X-radiation, gamma radiation, corpuscular radiation, or cosmic radiation
    • G01T1/16—Measuring radiation intensity
    • G01T1/1603—Measuring radiation intensity with a combination of at least two different types of detector
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01T—MEASUREMENT OF NUCLEAR OR X-RADIATION
    • G01T1/00—Measuring X-radiation, gamma radiation, corpuscular radiation, or cosmic radiation
    • G01T1/02—Dosimeters
    • G01T1/026—Semiconductor dose-rate meters
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01T—MEASUREMENT OF NUCLEAR OR X-RADIATION
    • G01T1/00—Measuring X-radiation, gamma radiation, corpuscular radiation, or cosmic radiation
    • G01T1/16—Measuring radiation intensity
    • G01T1/24—Measuring radiation intensity with semiconductor detectors

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
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  • High Energy & Nuclear Physics (AREA)
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  • Measurement Of Radiation (AREA)

Abstract

The invention discloses an eye lens dosage measuring device and a method, comprising a Si-EJ276 detector and a control module; the Si-EJ276 detector comprises a Si detector and an EJ276 crystal detector which are sequentially arranged along the incidence direction of radiation particles, the Si detector is coupled with the EJ276 crystal detector, and the EJ276 crystal detector comprises an EJ276 crystal and a silicon photomultiplier; the control module is arranged on the Si-EJ276 detector, the EJ276 crystal detector outputs signal waveforms with different speed components under the condition of different radiation particles, and the control module is used for carrying out pulse signal processing on output signals of the EJ276 crystal detector, distinguishing the radiation particles and obtaining the energy and flux of the radiation particles. According to the invention, the Si detector and the EJ276 crystal detector are coupled to form the Si-EJ276 detector, the EJ276 crystal has small density, the EJ276 crystal and the crystalline lens have good structural equivalence, the measurement precision of the detector is obviously improved, the charged particle type discrimination and energy measurement are realized, the measurement function of the energy transmission line density LET is realized, and the purpose of composite measurement is achieved.

Description

Ophthalmic lens dosimetry device and method
Technical Field
The invention relates to the technical field of spatial radiation detection, in particular to a device and a method for measuring eye lens dose.
Background
In the space station, astronauts are necessarily exposed to the space radiation environment in the cabin, and space ionizing radiation is one of important factors influencing the health factors of the astronauts in manned space flight. Space radiation dosimetry has been a significant concern to scientists because of the threat of space radiation to human space exploration activities. In particular, the risk of neurodegenerative diseases caused by charged particles or the like in space is high. The eye lens is a radiation sensitive organ, and the radiation monitoring of the eye lens has important significance for health assessment of astronauts. At present, the detection of the radiation dose of the eye crystal depends on a passive dose monitoring device, such as a pyroelectric film and the like, for example, the measurement of the eye crystal only depends on a passive pyroelectric detector for measurement, only the accumulated dose is obtained, and the real-time monitoring cannot be carried out; the energy spectrum of the particles is obtained through the scintillation crystal, however, the difference between the density of the scintillation crystal and the density of the eye crystal is large, the tissue equivalence is poor, and therefore the measurement accuracy is poor.
Disclosure of Invention
In order to solve the above technical problems, an object of the present invention is an intraocular lens dose measuring device comprising a Si-EJ276 detector and a control module;
the Si-EJ276 detector comprises a Si detector and an EJ276 crystal detector which are sequentially arranged along the incidence direction of radiation particles, the Si detector is coupled with the EJ276 crystal detector, the EJ276 crystal detector comprises an EJ276 crystal and a silicon photomultiplier, and the silicon photomultiplier is coupled with the EJ276 crystal;
the control module is arranged on the Si-EJ276 detector, the EJ276 crystal detector outputs signal waveforms with different speed components under the condition of different radiation particles, and the control module is used for distinguishing the radiation particles and obtaining the energy and the flux of the radiation particles after pulse signal processing is carried out on the output signal of the EJ276 crystal detector.
By adopting the technical scheme, the EJ276 crystal has the diameter of 0.8-1.2 inches and the thickness of 0.8-1.2 inches.
By adopting the technical scheme, the EJ276 crystal has the diameter of 1 inch and the thickness of 1 inch.
By adopting the technical scheme, the sensitive area of the Si detector is 15-20mm in diameter, and the thickness is 280-320 mu m.
By adopting the technical scheme, the Si-EJ276 detector comprises a shell, and the shell wraps the coupled Si detector and the EJ276 crystal detector.
By adopting the technical scheme, the Si-EJ276 detector comprises a preamplifier and an analog-to-digital converter;
the output end of the Si detector and the output end of the silicon photomultiplier are respectively coupled with a preamplifier, and the preamplifiers are used for preliminarily amplifying signals output by the Si detector and electric signals output by the silicon photomultiplier;
the analog-to-digital converter is coupled with the output end of a preamplifier on the Si detector and is used for performing analog-to-digital conversion on the signal amplified by the preamplifier.
By adopting the technical scheme, the Si-EJ276 detector further comprises a bias power supply, and the bias power supply is arranged inside the Si-EJ276 detector.
Another object of the present invention is to provide a spatial radiation detection method, comprising:
when the radiation particles pass through the Si detector, the radiation particles interact with Si atoms, and an energy loss value delta E is recorded;
when secondary particles generated after the radiation particles interact with Si atoms or original radiation particles which do not interact with the Si atoms pass through an EJ276 crystal detector, the EJ276 crystal absorbs the residual energy of the particles;
dividing the energy loss value delta E measured by the Si detector by the thickness of the Si detector to obtain an energy transmission line density spectrum;
the EJ276 crystal detector generates signal waveforms with different speed components under the condition of different radiation particles, and the control module distinguishes the radiation particles and obtains the energy and the flux of the radiation particles after pulse signal processing is carried out on the output signals of the EJ276 crystal detector.
By adopting the above technical scheme, the distinguishing the radiation particles and obtaining the energy and flux of the radiation particles comprises:
integrating the attenuated slow component in the signal waveform to obtain a neutron event, and obtaining the energy spectrum and flux information of fast neutrons in the neutron event;
and identifying the fast component in the signal waveform as the event of the gamma ray, and obtaining the energy spectrum information of the gamma ray after the gamma ray is distinguished from the neutron.
By adopting the technical scheme, the energy and flux of thermal neutrons and fast neutrons are obtained in the event of neutrons, including;
in the event of neutrons, the energy spectrum and flux information of fast neutrons are obtained by reversely deducing the kinetic energy of protons.
The invention has the beneficial effects that: according to the invention, the Si detector and the EJ276 crystal detector are coupled to form the Si-EJ276 detector, the EJ276 crystal has small density, the EJ276 crystal and the crystalline lens have good tissue equivalence, the measurement precision of the detector is obviously improved, the charged particle type discrimination and energy measurement are realized, the measurement function of the energy transmission linear density LET is realized, the purpose of composite measurement is achieved, the accumulated dose is obtained, the information of the time variation and the depth distribution of the dose of the crystalline lens is also obtained, and the real-time detection requirement is met.
Drawings
Fig. 1 is a system block diagram of embodiment 1 of the present invention.
Fig. 2 is a schematic diagram of the structure of the Si-EJ276 detector of the present invention.
Fig. 3 is a bottom view of fig. 2.
Fig. 4 is a partially enlarged schematic view of a portion a of fig. 3.
FIG. 5 is a schematic flow chart of example 2 of the present invention.
Fig. 6 is a schematic diagram of the pulse signal processing circuit of the Si detector of the present invention.
Fig. 7 is a schematic diagram of an EJ276 pulse amplitude discriminator pulse signal processing circuit of the present invention.
FIG. 8 is a functional block diagram of a data processing and communication control unit according to the present invention.
The numbering in the figures illustrates: 11. a Si detector; 12. an EJ276 crystal detector; 13. a housing; 14. a silicon photomultiplier tube; 15. a preamplifier; 16. an analog-to-digital converter; 17. EJ276 crystals; 2. and a control module.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments.
Examples of which are illustrated in the accompanying drawings, wherein like reference numerals refer to the same or similar elements or elements having the same or similar function throughout. The embodiments described below with reference to the drawings are illustrative and intended to be illustrative of the invention and are not to be construed as limiting the invention.
Example 1
Referring to fig. 1, an embodiment 1 of the present invention provides an intraocular lens dose measuring device, including a Si-EJ276 detector and a control module 2, the Si-EJ276 detector includes a Si detector 11 and an EJ276 crystal detector 12 which are sequentially arranged along an incident direction of radiation particles, the Si detector 11 is coupled to the EJ276 crystal detector 12, the EJ276 crystal detector 12 includes an EJ276 crystal 17 and a silicon photomultiplier 14, the silicon photomultiplier 14 is coupled to the EJ276 crystal 17, the EJ276 crystal 17 performs photoelectric conversion using the silicon photomultiplier 14, the silicon photomultiplier 14 can transmit at a light speed, and photoelectric conversion can be realized in an extremely short time; the control module 2 is arranged on the Si-EJ276 detector, the EJ276 crystal detector 12 outputs signal waveforms of different speed components under the condition of different radiation particles, and the control module 2 is used for distinguishing the radiation particles and obtaining the energy and flux of the radiation particles after pulse signal processing is carried out on the output signal of the EJ276 crystal detector 12.
Wherein the EJ276 crystals 17 have a diameter of 0.8 to 1.2 inches and a thickness of 0.8 to 1.2 inches. Preferably, the crystal 17 of the present embodiment EJ276 has a diameter of 1 inch and a thickness of 1 inch. In addition, the sensitive area of the Si detector is 15-20mm in diameter and 280-320 mu m in thickness. In order to match the EJ276 crystal 17 with a diameter of 1 inch, the present embodiment uses a Si detector 11 with a sensitive area diameter of 18mm and a thickness of 300 μm, the Si detector 11 is coupled to the front end of the EJ276 crystal detector 12 for obtaining the energy transmission line density spectrum LET, for example, the energy loss value Δ E measured by the Si detector 11 is divided by the thickness of the Si detector 11. There are also spatial high energy particles that can be incident on the EJ276 crystal detector 12 from various directions and for high energy particles can traverse the entire EJ276 crystal detector 12, while for different directions the path length of the traversing particle in the EJ276 crystal detector 12 is different and the energy of the particle cannot be estimated by the energy deposition of the EJ276 crystal detector 12. Therefore, the embodiment couples the Si detector 11 to the front end of the EJ276 crystal detector 12, and performs coincidence measurement between the Si detector 11 and the EJ276 crystal detector 12, thereby realizing measurement of only particles passing through the Si detector 11 and the EJ276 crystal detector 12.
Referring to fig. 2, 3 and 4, the Si-EJ276 detector further includes a housing 13, the housing 13 encloses the coupled Si detector 11 and EJ276 crystal detector 12, and the Si detector 11 and EJ276 crystal detector 12 can be well coupled by being packaged by the housing 13. In use, a Si-EJ276 detector is installed in the space station to perform measurements of charged particles, gamma rays, and neutrons.
Continuing to refer to fig. 1, the Si-EJ276 detector includes a preamplifier 15 and an analog-to-digital converter 16, the output terminal of the Si detector 11 and the output terminal of the silicon photomultiplier 14 are respectively coupled with the preamplifier 15, the preamplifier 15 is used for preliminarily amplifying the signal output by the Si detector 11 and the electrical signal at the output terminal of the silicon photomultiplier 14; an analog-to-digital converter 16 is coupled to the output of the preamplifier 15 on the Si detector 11, said analog-to-digital converter 16 being adapted to perform an analog-to-digital conversion on the signal amplified by the preamplifier 15.
And a bias voltage is required to be set for the Si-EJ276 detector, so the Si-EJ276 detector of the embodiment also comprises a bias voltage power supply which is arranged inside the Si-EJ276 detector.
Compared with a scintillation crystal, the EJ276 crystal 17 has the advantages that the density of the EJ276 crystal 17 is smaller, the EJ276 crystal 17 has better tissue equivalence with a crystalline lens, and the measurement accuracy of the detector is remarkably improved.
Example 2
Referring to fig. 5, embodiment 2 of the present invention provides a spatial radiation detection method, including the following steps:
in step 101, the radiation particles interact with the Si atoms as they pass through the Si detector 11, and the energy loss value Δ E is recorded.
Illustratively, when radiation particles (including charged and uncharged particles) are incident from the front end, the radiation particles interact with Si atoms when passing through the Si detector 11, and the energy loss value Δ E in the Si detector 11 is recorded, and since the Si detector 11 is not very large in volume, there is a high probability that the generated secondary particles or the original radiation particles which do not interact will continue to move along the incident direction or at an angle to the incident direction after the radiation particles interact with the Si atoms for the space with high energy.
In step 102, when the secondary particles generated after the interaction of the radiation particles with the Si atoms or the original radiation particles without interaction pass through the EJ276 crystal detector 12, the EJ276 crystal 17 absorbs the remaining energy of the particles.
In step 103, the energy loss value Δ E measured by the Si detector 11 is divided by the thickness of the Si detector 11 to obtain the energy transmission line density spectrum LET.
By way of example, the energy resolution is within 10% by adopting a Si detector for measurement, and the function of measuring the energy transfer linear density LET can be realized. The measurement accuracy of the dosage is within 10 percent, and the LET measurement index of 0.4 keV/mum-750 keV/mum can also meet the requirement at the same time. LET spectrum measurement takes the characteristics of space particle spectrum into consideration, and measures the spectrum covering proton, alpha, 6 Li、 12 C、 24 Si、 56 Fe, etc., with energies covering protons of 10MeV/u-1GeV, so LET covers 0.42keV/μm-320keV/μm.
In step 104, the EJ276 crystal detector 12 generates signal waveforms with different fast and slow components under different radiation particles, and the control module 2 performs pulse signal processing on the output signal of the EJ276 crystal detector 12 to distinguish the radiation particles and obtain the energy and flux of the radiation particles.
Illustratively, first, the EJ276 crystal detector 12 generates signal waveforms with different fast and slow components under different radiation particles; and integrating the decaying slow component in the signal waveform to obtain an event of a neutron, and identifying the fast component in the signal waveform as an event of the gamma ray.
Illustratively, in the event of a neutron, the energy spectrum and flux information of the fast neutron is obtained by reversely deducing the kinetic energy of the proton, and the energy spectrum information of the gamma ray is obtained after the gamma ray is distinguished from the neutron.
Illustratively, the control module comprises a pulse signal processing unit and a data processing and communication control unit. On one hand, the pulse signal processing unit mainly comprises a Si detector pulse signal processing circuit and an EJ276 pulse amplitude discriminator pulse signal processing circuit, wherein after an output signal of a silicon detector passes through a charge preamplifier, the output signal firstly passes through a zero cancellation circuit to adjust the waveform, then the output signal is divided into 2 paths, one path is filtered and formed to carry out amplitude measurement, and the other path is rapidly amplified to carry out trigger time analysis. The pulse signal processing circuitry for the Si detector is shown in fig. 6. In addition, for the EJ276 crystal output, in order to measure the energy in a large dynamic range, the output signal is subjected to high-low gain double-path amplification, and a pulse signal processing circuit of the EJ276 pulse amplitude discriminator is shown in FIG. 7. On the other hand, the data processing and communication control unit mainly comprises a multi-channel amplitude signal acquisition circuit, a multi-channel time signal discrimination circuit, a module state monitoring circuit, a main control circuit and a communication interface circuit, and the specific structure is shown in detail in fig. 8. The EJ276 crystal detector fires and records the signal amplitude and time and the n/gamma discrimination factor for measuring neutrons, gamma and charged particles.
In conclusion, the Si detector and the EJ276 crystal 17 detector are coupled to form the Si-EJ276 detector, the EJ276 crystal 17 has low density, the EJ276 crystal 17 and the crystalline lens have good tissue equivalence, the measurement precision of the detector is obviously improved, the charged particle type discrimination and energy measurement are realized, the measurement function of the energy transmission line density LET is realized, the purpose of composite measurement is achieved, the accumulated dose is obtained, the information of the time variation and the depth distribution of the dose of the crystalline lens is also obtained, and the real-time detection requirement is met.
The above-mentioned embodiments are merely preferred embodiments for fully illustrating the present invention, and the scope of the present invention is not limited thereto. The equivalent substitutions or changes made by the person skilled in the art on the basis of the present invention are all within the protection scope of the present invention. The protection scope of the invention is subject to the claims.

Claims (10)

1. An intraocular lens dosimetry device comprising a Si-EJ276 probe and a control module;
the Si-EJ276 detector comprises a Si detector and an EJ276 crystal detector which are sequentially arranged along the incidence direction of radiation particles, the Si detector is coupled with the EJ276 crystal detector, the EJ276 crystal detector comprises an EJ276 crystal and a silicon photomultiplier, and the silicon photomultiplier is coupled with the EJ276 crystal;
the control module is arranged on the Si-EJ276 detector, the EJ276 crystal detector outputs signal waveforms with different speed components under the condition of different radiation particles, and the control module is used for distinguishing the radiation particles and obtaining the energy and the flux of the radiation particles after pulse signal processing is carried out on the output signal of the EJ276 crystal detector.
2. The ophthalmic lens dosimetry device of claim 1, wherein: the EJ276 crystals have a diameter of 0.8 to 1.2 inches and a thickness of 0.8 to 1.2 inches.
3. The ophthalmic lens dosimetry device of claim 2, wherein: the EJ276 crystal was 1 inch in diameter and 1 inch thick.
4. The ophthalmic lens dosimetry device of claim 1, wherein: the sensitive area of the Si detector is 15-20mm in diameter, and the thickness is 280-320 mu m.
5. The ophthalmic lens dosimetry device of claim 1, wherein: the Si-EJ276 detector includes a housing that encases the coupled Si detector and EJ276 crystal detector.
6. The ophthalmic lens dosimetry device of claim 1, wherein: the Si-EJ276 detector comprises a preamplifier and an analog-to-digital converter;
the output end of the Si detector and the output end of the silicon photomultiplier are respectively coupled with a preamplifier, and the preamplifiers are used for preliminarily amplifying signals output by the Si detector and electric signals output by the silicon photomultiplier;
the analog-to-digital converter is coupled with the output end of a preamplifier on the Si detector and is used for performing analog-to-digital conversion on the signal amplified by the preamplifier.
7. The ophthalmic lens dosimetry device of claim 5, wherein: the Si-EJ276 probe also includes a bias power supply that is located inside the Si-EJ276 probe.
8. An intraocular lens dosimetry method comprising:
when the radiation particles pass through the Si detector, the radiation particles interact with Si atoms, and an energy loss value delta E is recorded;
when secondary particles generated after the interaction between the radiation particles and Si atoms or original radiation particles which do not interact pass through the EJ276 crystal detector, the EJ276 crystal absorbs the residual energy of the particles;
dividing the energy loss value delta E measured by the Si detector by the thickness of the Si detector to obtain an energy transmission line density spectrum;
the EJ276 crystal detector generates signal waveforms with different speed components under the condition of different radiation particles, and the control module distinguishes the radiation particles and obtains the energy and the flux of the radiation particles after pulse signal processing is carried out on the output signals of the EJ276 crystal detector.
9. The ophthalmic lens dosimetry method of claim 8, wherein said distinguishing of the radiating particles and obtaining the energy and flux of the radiating particles comprises:
integrating the attenuated slow component in the signal waveform to obtain the event of neutrons, and obtaining the energy spectrum and flux information of fast neutrons in the event of neutrons;
and identifying the fast component in the signal waveform as the event of the gamma ray, and obtaining the energy spectrum information of the gamma ray after the gamma ray is distinguished from the neutron.
10. The ocular lens dosimetry method of claim 9, wherein said obtaining of energy spectrum and flux information of fast neutrons in the event of neutrons comprises;
in the event of a neutron, the energy spectrum and flux information of a fast neutron are obtained by reversely deducing the kinetic energy of the proton.
CN202011348473.2A 2020-11-26 2020-11-26 Ophthalmic lens dosimetry device and method Active CN112526576B (en)

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Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1572636A (en) * 1967-06-15 1969-06-27
TW201119636A (en) * 2009-11-02 2011-06-16 Salutaris Medical Devices Inc Methods and devices for delivering appropriate minimally-invasive extraocular radiation
CN102628951A (en) * 2012-03-30 2012-08-08 中国科学院合肥物质科学研究院 Radiation dose measurement method based on quantum dot electroluminescent principle
CN206362944U (en) * 2016-12-27 2017-07-28 同方威视技术股份有限公司 Detection system for fast neutron imaging

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1572636A (en) * 1967-06-15 1969-06-27
DE1764467A1 (en) * 1967-06-15 1971-09-16 Atomic Energy Commission microscope
TW201119636A (en) * 2009-11-02 2011-06-16 Salutaris Medical Devices Inc Methods and devices for delivering appropriate minimally-invasive extraocular radiation
CN102628951A (en) * 2012-03-30 2012-08-08 中国科学院合肥物质科学研究院 Radiation dose measurement method based on quantum dot electroluminescent principle
CN206362944U (en) * 2016-12-27 2017-07-28 同方威视技术股份有限公司 Detection system for fast neutron imaging

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