CN112386810B - Cooling type photodynamic therapy head for intracavity therapy - Google Patents
Cooling type photodynamic therapy head for intracavity therapy Download PDFInfo
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- CN112386810B CN112386810B CN202110068954.6A CN202110068954A CN112386810B CN 112386810 B CN112386810 B CN 112386810B CN 202110068954 A CN202110068954 A CN 202110068954A CN 112386810 B CN112386810 B CN 112386810B
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/06—Radiation therapy using light
- A61N5/0613—Apparatus adapted for a specific treatment
- A61N5/062—Photodynamic therapy, i.e. excitation of an agent
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/06—Radiation therapy using light
- A61N5/0613—Apparatus adapted for a specific treatment
- A61N5/0625—Warming the body, e.g. hyperthermia treatment
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- G—PHYSICS
- G05—CONTROLLING; REGULATING
- G05D—SYSTEMS FOR CONTROLLING OR REGULATING NON-ELECTRIC VARIABLES
- G05D23/00—Control of temperature
- G05D23/19—Control of temperature characterised by the use of electric means
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N2005/002—Cooling systems
- A61N2005/005—Cooling systems for cooling the radiator
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/06—Radiation therapy using light
- A61N2005/0626—Monitoring, verifying, controlling systems and methods
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/06—Radiation therapy using light
- A61N2005/063—Radiation therapy using light comprising light transmitting means, e.g. optical fibres
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Abstract
The invention provides a semiconductor narrow-spectrum light emitting array and a cooling type photodynamic therapy head for intracavity therapy, wherein the therapy head comprises a semiconductor narrow-spectrum light emitting array formed by surrounding the outer side wall of a cooling cavity, a transparent therapy head shell is arranged on the outer side of the semiconductor narrow-spectrum light emitting array, a cooling liquid inlet pipe and a cooling liquid outlet pipe are arranged in the cooling cavity, the cooling liquid inlet pipe, the cooling liquid outlet pipe, the cooling cavity and the therapy head shell form a therapy part inserted into an inner cavity of a human body, the end part of the therapy part is connected with a handle part, the handle part is connected with a therapy end liquid-electricity separation plug, the therapy end liquid-electricity separation plug is arranged at one end of a connecting pipe, the other end of the connecting pipe is connected with a host end liquid-electricity separation plug, and the host end liquid-electricity separation plug. The invention is suitable for the intracavity photodynamic therapy, has good cooling effect, solves the problem of protecting mucosal tissue in the intracavity photodynamic therapy and avoids causing the thermal damage of the mucosal tissue.
Description
Technical Field
The invention relates to a semiconductor narrow-spectrum light emitting array, in particular to a cooling type intracavity treatment head adopting a modern refrigeration technology to set temperature and control constant temperature.
Background
The progress of modern science and technology continuously pushes the progress and development of medical science. The development and popularization of modern photodynamic medicine provide safer, effective and convenient treatment means for the treatment of certain traditional diseases, and open up a new treatment way for diseases which can not be treated by the traditional medical treatment method.
In recent years, the use of photodynamic therapy has been widely used not only for the treatment of some body surface diseases, but also for the treatment of malignant tumors. For example: the traditional Chinese medicine composition has obvious curative effect on malignant tumors such as skin squamous cell carcinoma, oral squamous cell carcinoma, basal cell carcinoma, gynecological cervical early-stage precancerous lesion and the like, and is consistently determined and regarded as important by the medical field.
The basic principle of photodynamic therapy is: a specific photosensitizer, which generates a photochemical reaction in biological tissue in cooperation with irradiation of a specific wavelength spectrum, is composed of oxygen, a photosensitizer, and visible light (usually laser light) as essential elements. Firstly, the tumor tissue selectively takes up the photosensitizer and stores the photosensitizer therein, and then the photosensitizer is activated after local irradiation of light with proper wavelength to generate a photosensitizing effect. The photosensitizer is a porphyrin molecule capable of absorbing and re-releasing special wavelength and has a tetrapyrrole group structure. The first generation photosensitizers were hematoporphyrin derivatives (HpD), diphaemoporphyrin esters (DHE). Because tumor cells have more LDL receptors than normal cells, photosensitizers are more accessible into tumor cells mediated by LDL receptors; porphyrins can passively diffuse into cells, and the efficiency of diffusion is related to extracellular pH, with lower pH values dispersing more. The metabolism of tumor tissue is accelerated, so that the extracellular pH value is lower than that of normal tissue, and more porphyrins enter tumor cells. Therefore, the photosensitizer can quickly form singlet oxygen under the action of a specific spectrum, and pathological tissues and tumor cells are quickly poisoned and killed under the environment to achieve the purpose of curing diseases.
In the process of photodynamic therapy, the combination of light and photosensitizer can generate larger heat in the process of irradiation therapy, and stronger 'photothermal effect' is formed in human tissues, and the accumulation of photothermal effect can form 'thermal injury' on the treatment part if heat dissipation treatment is not carried out. Generally, the photodynamic therapy of the body surface can be implemented by cooling with cold air and spraying a coolant, but cooling is a problem to be solved when performing photodynamic therapy on some organs in cavities, and particularly when performing photodynamic therapy on delicate mucosal tissues such as vagina, cervix, oral cavity, anus and the like, if effective cooling is not performed, thermal damage of the mucosal tissues is very easily caused, so that the effective prevention of photothermal damage of the mucosal tissues in the process of photodynamic therapy on the inner cavities of a human body is a technical problem to be solved.
Disclosure of Invention
The invention aims to provide a cooling type photodynamic therapy head for intracavity therapy, which can effectively cool the therapy head and avoid the thermal damage of mucosa tissues during photodynamic therapy.
The technical scheme of the invention is as follows:
the semiconductor narrow-spectrum light emitting array comprises a semiconductor narrow-spectrum light emitting unit, wherein the semiconductor narrow-spectrum light emitting unit takes a flexible circuit board as a substrate, the flexible circuit board welded with the semiconductor narrow-spectrum light emitting unit surrounds the outer side wall of a cooling cavity to form the semiconductor narrow-spectrum light emitting array, cooling liquid is conveyed to the top end of the cooling cavity through a cooling liquid inlet pipe in a forced diversion mode and flows out, then the cooling liquid is filled in the whole cooling cavity and flows back to a cooling liquid outlet pipe, and therefore forced cooling is conducted on the semiconductor narrow-spectrum light emitting array.
The utility model provides an utilize above the luminous array preparation of semiconductor narrow spectrum for the cooled type intracavity treatment photodynamic therapy head that forms, include that the lateral wall around cooling cavity forms the luminous array of semiconductor narrow spectrum, be provided with transparent treatment head shell in the outside of the luminous array of semiconductor narrow spectrum, install coolant liquid feed pipe and coolant liquid drain pipe in cooling cavity, coolant liquid feed pipe, coolant liquid drain pipe, cooling cavity and treatment head shell constitute the treatment portion that inserts human inner chamber, the end connection handle portion of treatment portion, handle portion connection treatment end liquid electricity separation plug, treatment end liquid electricity separation plug set up the one end at the connecting pipe, and the other end of connecting pipe is connected to host computer end liquid electricity separation plug, host computer end liquid electricity separation plug is connected to the photodynamic therapy host computer.
The handle part is provided with a light source working electrode socket and a signal detection electrode socket.
The semiconductor narrow-spectrum light emitting array is connected with the light source working electrode socket.
And a detection probe for detecting the temperature of the cooling cavity is also arranged in the side wall of the cooling cavity.
The detection probe is connected to a signal detection electrode socket.
The cooling cavity is a cylinder structure with an opening at one end close to the handle part and a closed end far away from the handle part, and the closed end of the cooling cavity is in a circular arc design.
The inlet of coolant liquid feed pipe is established at handle portion, the liquid outlet of coolant liquid feed pipe extends to the cooling cavity blind end and is used for carrying the coolant liquid in whole cooling cavity, the coolant liquid drain pipe is used for discharging the coolant liquid in the cooling cavity completely.
The cross-sectional area of the cooling liquid inlet pipe is larger than that of the cooling liquid outlet pipe.
The cooling liquid inlet pipe and the cooling liquid outlet pipe are connected to a cooling medium generator of the host machine, the light source working electrode socket is connected to a light source energy control unit of the host machine, the signal detection electrode socket is connected to a PID temperature adjusting unit of the host machine, and the cooling medium generator, the light source energy control unit and the PID temperature adjusting unit are all connected to a CPU unit of the host machine.
Compared with the prior art, the invention has the beneficial effects that: the flexible circuit board welded with the semiconductor narrow-spectrum light-emitting unit forms a semiconductor narrow-spectrum light-emitting array around the outer side wall of the cooling cavity, the cooling liquid flows through the bottom of the light-emitting array for cooling in the cooling cavity of the treatment head, the structure is novel, the illumination intensity and the target property during light treatment can be ensured, meanwhile, the flowing of the cooling liquid can not influence the illumination, especially, the temperature of the treatment head can be accurately controlled under the monitoring of the embedded temperature probe, the working temperature generated during the working of a light source is thoroughly solved, more importantly, the cooling liquid can effectively absorb the 'photothermal effect' generated by light and a photosensitizer during treatment, the cooling cavity ensures that the cooling liquid has no dead angle in the cooling cavity of the treatment head, no bubble flows to maximize the cooling efficiency, the detection probe can uniformly detect the temperature change of the treatment head, and the temperature signal led out by the electrode can be conveniently used for a computer to carry out temperature regulation and constant, the invention has simple structure, is suitable for the intracavity photodynamic therapy, has good cooling effect, fundamentally solves the problem of protecting mucosal tissues in the intracavity photodynamic therapy and avoids causing the thermal injury of the mucosal tissues. Solves the road blocking tiger problem to be solved urgently for the application of photodynamic medical technology in intracavity treatment. Will certainly make a great contribution to the development of photodynamic medicine.
Drawings
Fig. 1 is a schematic view of the overall structure of the treatment head of the present invention.
Fig. 2 is a schematic sectional structure of the treatment head of the present invention.
Fig. 3 is a schematic cross-sectional structure of the treatment head of the present invention.
Fig. 4 is a schematic view of the treatment head connection of the present invention.
Fig. 5 is a schematic diagram of the control principle of the present invention.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
As shown in fig. 3, a semiconductor narrow-spectrum light emitting array includes a semiconductor narrow-spectrum light emitting unit 10, the semiconductor narrow-spectrum light emitting unit 10 uses a flexible circuit board as a substrate, the flexible circuit board welded with the semiconductor narrow-spectrum light emitting unit 10 surrounds the outer side wall of a cooling cavity 11 to form the semiconductor narrow-spectrum light emitting array, a cooling liquid is forcibly guided by a cooling liquid inlet pipe 15 to be conveyed to the top end of the cooling cavity 11 to flow out, and then is fully filled in the whole cooling cavity 11 and flows back to a cooling liquid outlet pipe 16, so as to perform forced cooling on the semiconductor narrow-spectrum light emitting array, and the wave of light emitted by the semiconductor narrow-spectrum light emitting unit 10 can be 400nm to 800nm or other specific wavelengths according to the matched wavelength of a photosensitizer.
As shown in fig. 1-5, a cooling type photodynamic therapy head for intracavity therapy manufactured by using the semiconductor narrow-spectrum light emitting array is characterized in that a cylindrical cooling cavity of the therapy head is made of a metal material with high heat conduction efficiency, the cooling cavity comprises a semiconductor narrow-spectrum light emitting array formed around the outer side wall of a cooling cavity 11, a therapy head shell 12 is arranged at the outer side of the semiconductor narrow-spectrum light emitting array, the therapy head shell 12 is made of a transparent material which does not block the narrow-spectrum light of the semiconductor, a cooling liquid inlet pipe 15 and a cooling liquid outlet pipe 16 are arranged in the cooling cavity 11, the cooling liquid inlet pipe 15, the cooling liquid outlet pipe 16, the cooling cavity 11 and the therapy head shell 12 form a therapy part 1 inserted into an inner cavity of a human body, the end part of the therapy part 1 is connected with a handle part 2, the handle part 2 is connected with a therapy end liquid-electricity separation plug 3, the therapy end liquid-electricity separation plug 3 is arranged, the other end of the connecting pipe 4 is connected to a host end liquid-electricity separation plug 5, and the host end liquid-electricity separation plug 5 is connected to the photodynamic therapy host. The handle portion 2 is provided with a light source working electrode socket 14 and a signal detection electrode socket 13.
The semiconductor narrow-spectrum light emitting array is connected with a light source working electrode socket 14.
And a detection probe 17 for detecting the temperature of the cooling cavity 11 is further mounted in the side wall of the cooling cavity 11. The detection probe 17 adopts a high-precision micro embedded temperature detector, the detection probe 17 is directly embedded in the capsule wall at the central part of the treatment head cooling cavity 11, the temperature change of the treatment head is uniformly detected, and a temperature signal led out by an electrode of the detection probe is convenient for a computer to carry out temperature regulation and constant temperature control.
The detection probe 17 is connected to the signal detection electrode socket 13.
The cooling cavity 11 is made of a metal heat conducting material, the cooling cavity 11 is an open end close to the handle part 2, a closed end far away from the handle part 2 is of a cylinder structure, and the closed end of the cooling cavity 11 is of an arc-shaped design.
The liquid inlet of the cooling liquid inlet pipe 15 is arranged on the handle part 2, the liquid outlet of the cooling liquid inlet pipe 15 extends to the closed end of the cooling cavity 11 to convey cooling liquid into the whole cooling cavity 11, and the cooling liquid outlet pipe 16 is used for completely discharging the cooling liquid in the cooling cavity 11.
The cooling mode of the therapeutic head adopts the forced cooling of the temperature-controllable refrigerating fluid; inside the treatment head, a cooling liquid single-tube forced conveying mode is invented, a cooling flow channel is of a 'differential flow channel' structure, namely cooling liquid is conveyed to the top end of a cooling cavity 11 of the treatment head through a cooling liquid inlet tube 15 in a forced flow guiding mode and flows out, then the cooling liquid is filled in the whole cooling cavity 11 and flows back to a cooling liquid outlet tube 16, the cross section area of the cooling liquid inlet tube 15 is larger than that of the cooling liquid outlet tube 16, the cross section area of the cooling liquid outlet tube 16 is the cross section area of a cavity in the cooling cavity 11 minus that of the cooling liquid inlet tube 15, and the cooling liquid is conveyed through the 'differential flow channel' due to the fact that the cross section area of the cooling liquid inlet tube 15 is larger than that of the cooling liquid outlet tube 16, so that no dead angle exists in the cooling cavity 11 of the treatment.
The cooling liquid inlet pipe 15 and the cooling liquid outlet pipe 16 are connected to a cooling medium generator of a host, the light source working electrode socket 14 is connected to a light source energy control unit of the host, the signal detection electrode socket 13 is connected to a PID temperature adjusting unit of the host, and the cooling medium generator, the light source energy control unit and the PID temperature adjusting unit are all connected to a CPU unit of the host. The light source energy control unit controls the luminous intensity of the semiconductor narrow-spectrum luminous array and adjusts the intensity of light according to different requirements, so that the accuracy of treatment is ensured. The PID temperature adjusting unit can adjust and control the temperature according to the temperature value detected by the detection probe 17 by controlling the flow and the flow speed of the cooling liquid, has high precision and good cooling effect, and effectively avoids the thermal injury of the mucosa tissue when the photodynamic therapy of the inner cavity is carried out.
The electrode wire signal detection line of the treatment head and the like are led out by adopting a connector, so that the treatment head is conveniently connected with a using host; the cooling liquid conveyer pipe adopts the soft resistant high microthermal combined material to make to at the high-efficient insulation material of pipe surface parcel in order to prevent that the temperature from giving off and causing the energy extravagant and temperature control inaccurate, with cooling liquid conveyer pipe, working electrode, detection electrode integration be a connecting pipe, adopt liquid electricity separation plug to connect respectively and use host computer and treatment head, the plug can be wantonly inserted to treatment head one end, is convenient for change the treatment head of different wavelength and different specifications.
Furthermore, it should be understood that although the present description refers to embodiments, not every embodiment may contain only a single embodiment, and such description is for clarity only, and those skilled in the art should integrate the description, and the embodiments may be combined as appropriate to form other embodiments understood by those skilled in the art.
Claims (4)
1. A cooled photodynamic therapy head for intracavity therapy is characterized by comprising a semiconductor narrow-spectrum light emitting array formed around the outer side wall of a cooling cavity (11), the semiconductor narrow-spectrum light emitting array comprises a semiconductor narrow-spectrum light emitting unit (10), the semiconductor narrow-spectrum light emitting unit (10) takes a flexible circuit board as a substrate, the flexible circuit board welded with the semiconductor narrow-spectrum light emitting unit (10) forms the semiconductor narrow-spectrum light emitting array around the outer side wall of the cooling cavity (11), a cooling liquid inlet pipe (15) and a cooling liquid outlet pipe (16) are installed on the cooling cavity (11), cooling liquid is conveyed to the top end of the cooling cavity (11) through the forced diversion of the cooling liquid inlet pipe (15) to flow out, and then flows back to the cooling liquid outlet pipe (16) through the whole cooling cavity (11) to carry out forced cooling on the semiconductor narrow-spectrum light emitting array, the cross-sectional area of the cooling liquid inlet pipe (15) is larger than that of the cooling liquid outlet pipe (16), a transparent treatment head shell (12) is arranged on the outer side of the semiconductor narrow-spectrum light emitting array, the cooling liquid inlet pipe (15), the cooling liquid outlet pipe (16), a cooling cavity (11) and the treatment head shell (12) form a treatment part (1) inserted into a human body inner cavity, the end part of the treatment part (1) is connected with a handle part (2), the handle part (2) is connected with a treatment end liquid-electricity separation plug (3), the treatment end liquid-electricity separation plug (3) is arranged at one end of a connecting pipe (4), the other end of the connecting pipe (4) is connected to a host end liquid-electricity separation plug (5), and the host end liquid-electricity separation plug (5) is connected to a photodynamic therapy host;
the handle part (2) is provided with a light source working electrode socket (14) and a signal detection electrode socket (13);
the semiconductor narrow-spectrum light emitting array is connected with a light source working electrode socket (14);
a detection probe (17) for detecting the temperature of the cooling cavity (11) is further mounted in the side wall of the cooling cavity (11);
the detection probe (17) is connected to a signal detection electrode socket (13).
2. The photodynamic therapy head for cooled intracavity therapy according to claim 1, wherein the cooling chamber (11) is a cylinder structure which is open at the end close to the handle part (2) and closed at the end far away from the handle part (2), and the closed end of the cooling chamber (11) is in the shape of a circular arc.
3. The cooled intracavity therapeutic photodynamic therapy head according to claim 2 wherein the inlet of the coolant inlet tube (15) is arranged on the handle portion (2), the outlet of the coolant inlet tube (15) extends to the closed end of the cooling chamber (11) for feeding the coolant into the cooling chamber (11), and the coolant outlet tube (16) is arranged for discharging the coolant from the cooling chamber (11) completely.
4. The photodynamic therapy head for cooled intracavity therapy according to claim 2, wherein the coolant inlet (15) and outlet (16) pipes are connected to a coolant generator of the host, the light source working electrode socket (14) is connected to a light source energy control unit of the host, the signal detection electrode socket (13) is connected to a PID temperature adjustment unit of the host, and the coolant generator, the light source energy control unit and the PID temperature adjustment unit are all connected to a CPU unit of the host.
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| Application Number | Priority Date | Filing Date | Title |
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| CN202110068954.6A CN112386810B (en) | 2021-01-19 | 2021-01-19 | Cooling type photodynamic therapy head for intracavity therapy |
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| CN202110068954.6A CN112386810B (en) | 2021-01-19 | 2021-01-19 | Cooling type photodynamic therapy head for intracavity therapy |
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| CN112386810B true CN112386810B (en) | 2021-04-27 |
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Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2683531A1 (en) * | 2008-11-07 | 2010-05-07 | Thomas B. Kerber | High intensity led light |
| CN1678252B (en) * | 2002-07-25 | 2011-06-29 | 乔纳森·S·达姆 | Appliance for transmitting heat energy, device for providing light of predetermined direction and light emitting device |
| CN205339863U (en) * | 2015-09-17 | 2016-06-29 | 深圳普门科技有限公司 | Intracavity photon therapeutic instrument |
| CN108778413A (en) * | 2015-12-18 | 2018-11-09 | 光治疗Asa公司 | Optical power therapentic equipment |
| US10705297B2 (en) * | 2010-11-23 | 2020-07-07 | Stone Aerospace, Inc. | Method of launching a spacecraft into low earth orbit using a non-line-of-sight optical power transfer system |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN2168207Y (en) * | 1993-08-31 | 1994-06-08 | 杨德友 | Water-heating device by use of waste heat |
| CN102788283B (en) * | 2012-07-26 | 2015-06-17 | 中山市科顺分析测试技术有限公司 | Flexible LED SMD lamp belt |
| CN202965003U (en) * | 2012-11-30 | 2013-06-05 | 宁波旭升机械有限公司 | Partial cooling device of mould |
| CN202972695U (en) * | 2012-12-20 | 2013-06-05 | 厦门百力达电子科技有限公司 | Candle lamp capable of emitting light in 360-degree range |
| CN203585849U (en) * | 2013-10-11 | 2014-05-07 | 李锡文 | LED candle lamp capable of dissipating heat through free flow of air from bottom to top |
| CN205825756U (en) * | 2016-06-02 | 2016-12-21 | 昆山市宏盛散热器制造有限公司 | Radiator |
| CN108954033A (en) * | 2018-01-19 | 2018-12-07 | 潘煜彬 | A kind of lens type LED bulb |
| CN208871365U (en) * | 2018-10-17 | 2019-05-17 | 启东盛丽光电科技有限公司 | A kind of LED light with spherical light field |
| CN209026702U (en) * | 2018-11-28 | 2019-06-25 | 广东洲明节能科技有限公司 | Radiator and LED street lamp |
| CN210740010U (en) * | 2019-11-27 | 2020-06-12 | 广州雄义精密五金有限公司 | Spliced LED light source module and combined lamp thereof |
-
2021
- 2021-01-19 CN CN202110068954.6A patent/CN112386810B/en active Active
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1678252B (en) * | 2002-07-25 | 2011-06-29 | 乔纳森·S·达姆 | Appliance for transmitting heat energy, device for providing light of predetermined direction and light emitting device |
| CA2683531A1 (en) * | 2008-11-07 | 2010-05-07 | Thomas B. Kerber | High intensity led light |
| US10705297B2 (en) * | 2010-11-23 | 2020-07-07 | Stone Aerospace, Inc. | Method of launching a spacecraft into low earth orbit using a non-line-of-sight optical power transfer system |
| CN205339863U (en) * | 2015-09-17 | 2016-06-29 | 深圳普门科技有限公司 | Intracavity photon therapeutic instrument |
| CN108778413A (en) * | 2015-12-18 | 2018-11-09 | 光治疗Asa公司 | Optical power therapentic equipment |
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