CN112120708A - Blood glucose monitoring intelligent device for developing and glucose-regulating 18F-FDG PET surviving cardiac muscle - Google Patents
Blood glucose monitoring intelligent device for developing and glucose-regulating 18F-FDG PET surviving cardiac muscle Download PDFInfo
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- CN112120708A CN112120708A CN202011015467.5A CN202011015467A CN112120708A CN 112120708 A CN112120708 A CN 112120708A CN 202011015467 A CN202011015467 A CN 202011015467A CN 112120708 A CN112120708 A CN 112120708A
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- A61B5/14532—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue for measuring glucose, e.g. by tissue impedance measurement
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- G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
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- G16H50/30—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for calculating health indices; for individual health risk assessment
Abstract
The invention discloses an intelligent device for monitoring blood sugar for developing and glucose-regulating 18F-FDG PET surviving myocardium, which comprises: the information acquisition module: the information acquisition module is used for acquiring blood sugar information of a detected person; an electronic transmission module for generating a blood glucose-time variation curve for the collected blood glucose information of the subject; a display module that displays a blood glucose-time variation curve generated by the electronic transmission module; a threshold comparison module that sets a risk threshold for hypoglycemia of the subject. According to the blood sugar-time change curve, the blood sugar condition of a patient is paid attention to in real time in the whole glucose load process, a certain dose of insulin is given when the blood sugar condition is obviously increased to be larger than a threshold value, then 18F-FDG is injected when the slope of a blood sugar reduction curve is maximum, the glucose uptake of the survival cardiac muscle is mobilized to the maximum extent, the image quality is improved, and the successful imaging is ensured; and the pain and the uncomfortable feeling of the patient who measures the blood sugar for many times in a short time can be avoided, and the compliance of the patient is increased.
Description
Technical Field
The invention relates to the field of blood sugar detection, in particular to an intelligent blood sugar monitoring device for developing and glucose-regulating 18F-FDG PET (positron emission tomography) viable myocardium.
Background
Viable myocardium refers to dysfunctional ischemic myocardium whose function is gradually restored after restoration of blood perfusion. Revascularization treatment can improve the cardiac function and prognosis of patients with coronary heart disease by restoring blood perfusion of ischemic myocardium, and is an important means for treating coronary heart disease. At present, the number of surviving cardiac muscles has been widely used to predict the recovery of post-revascularization contractile function of patients with coronary heart disease and heart failure, reversal of ventricular remodeling, improvement of quality of life, exercise capacity and survival rate, which are important bases for guiding clinical decision. Among various noninvasive imaging technologies for evaluating the survival myocardium, 18F-FDG Positron Emission Tomography (PET) is the current 'gold standard' for evaluating the survival myocardium, and the evaluation of the survival myocardium by combining with resting myocardium perfusion imaging has important significance for guiding revascularization treatment and prognosis judgment.
At present, the clinical multi-application oral glucose load is combined with insulin to regulate blood sugar, after a certain amount of glucose is orally taken, the blood sugar is measured for multiple times, when the blood sugar of a patient is obviously increased to be larger than a threshold value, a certain amount of insulin is injected, the blood sugar is closely monitored, the blood sugar level reaches the standard (reference guidance), an imaging agent 18F-FDG is injected, imaging is carried out after 1 hour, the image quality of 18F-FDG myocardial metabolism imaging is good and poor, the timing of 18F-FDG injection needs to be accurately grasped depending on the glucose load and the insulin level in vivo to a great extent, and therefore the blood sugar regulation process is the key of the success of 18F-FDG myocardial metabolism imaging and the image quality. In addition, this method carries a risk that the patient may have a hypoglycemic reaction, which can have serious consequences if not discovered and rescued in a timely manner.
Disclosure of Invention
Aiming at the defects in the prior art, the invention aims to provide the intelligent blood glucose monitoring device for developing and glucose-regulating 18F-FDG PET viable myocardium, and the improvement of the blood glucose regulating process is the key for successful development of 18F-FDG PET myocardium metabolism, image quality guarantee and safety guarantee in the blood glucose regulating process of a tested person.
In order to achieve the purpose, the invention provides the following technical scheme:
an intelligent device for monitoring blood sugar by developing and glucose-regulating 18F-FDG PET surviving myocardium, comprising: the information acquisition module: the information acquisition module is used for acquiring blood sugar information of a detected person;
the electronic transmission module is used for generating a blood glucose change curve for the collected blood glucose information of the examinee;
the display module displays the blood sugar change curve generated by the electronic transmission module;
a threshold comparison module that sets a risk threshold for hypoglycemia of the subject and compares a lowest blood glucose value of the subject with the threshold;
the alarm module alarms when the threshold comparison module detects that the blood sugar value of the checked person is lower than the threshold;
and the output end of the main control module is electrically connected with the input ends of the information acquisition module, the electronic transmission module and the threshold comparison module respectively.
Furthermore, the output end of the threshold comparison module is electrically connected with the input end of the alarm module, and the electronic transmission module is electrically connected with the input end of the display module.
By adopting the technical scheme, the blood sugar change curve is generated through the electronic transmission module, medical staff can pay attention to the blood sugar condition of a patient in real time in the whole glucose load process according to the blood sugar change curve, a certain dose of insulin is given when the blood sugar of the patient is obviously increased to be larger than a threshold value, then 18F-FDG is injected when the slope of the blood sugar decrease curve is maximum, the glucose uptake of the living cardiac muscle is mobilized to the maximum extent, the image quality is improved, and the successful development is ensured; the pain and discomfort caused by pricking blood sugar measured by a patient for multiple times in a short time can be avoided, and the compliance of the patient is improved; and through the threshold value comparison module, when the patient has hypoglycemia, namely the blood sugar value is lower than the set threshold value, the alarm module is triggered to inform medical personnel to process, so that serious consequences are avoided.
Further, still include the blood glucose meter main part, information acquisition module, electron transmission module, display module, threshold value contrast module, alarm module and main control module all set up in the blood glucose meter main part, one side of blood glucose meter main part is through rotating locating part fixedly connected with sealed cowling.
Further, it includes two fixed blocks, two to rotate the locating part the fixed block symmetry is fixed in one side of blood glucose meter main part, two fixedly connected with fixed axle between the fixed block, the surface cover of fixed axle is equipped with fixed pipe, the sealed cowling is fixed in one side on fixed pipe surface.
Through adopting above-mentioned technical scheme, can be when not using the blood glucose meter main part through setting up the sealed cowling, seal the protection to one side that the blood glucose meter main part was provided with the inductor, can prevent foreign matter adhesion such as dust on the inductor, influence the accuracy that detects.
Furthermore, an adjusting groove is symmetrically formed in one side of the inner surface of the fixed pipe, an arc-shaped block is fixedly connected to one side of the inner wall of the adjusting groove through an elastic piece, a stop block is symmetrically and fixedly connected to the other side of the inner surface of the fixed pipe, two limiting grooves are formed in two sides of the surface of the fixed shaft, and the two limiting grooves and the axis of the fixed shaft are arranged in a one-hundred-eighty degree mode.
Through adopting above-mentioned technical scheme, rotate the angle that the sealed cowling can be adjusted to the locating part through setting up, rotate the sealed cowling one hundred eighty degrees when using to it is spacing, make things convenient for the patient to use.
Furthermore, the equal fixedly connected with locating lever in both sides of arc piece arcwall face bottom, fixed intraductal wall bottom and the both sides that are located the arc piece have all seted up the locating hole, two one side that the fixed block is relative just is located the rear side fixedly connected with dog of fixed pipe.
Through adopting above-mentioned technical scheme, through setting up the arc piece and the laminating of fixed axle, when rotating fixed pipe, make rotate more level and smooth between fixed axle and the fixed pipe, and set up the dog and make fixed pipe can only rotate one hundred eighty degrees, the fixture block corresponds convenient operation with the spacing groove this moment.
Further, the both sides of blood glucose meter main part are first connecting band of fixedly connected with and second connecting band respectively, the one end fixedly connected with tightness adjusting device of second connecting band, tightness adjusting device includes the mounting bracket, one side of mounting bracket inner wall is rotated and is connected with the winding axle, the one end of first connecting band with winding axle fixed connection.
Through adopting above-mentioned technical scheme, can twine first connecting band through rotating the winding week to the elasticity when adjusting to wear.
Further, the top sliding connection of winding axle has the sleeve pipe, the top fixedly connected with nut of mounting bracket, the sheathed tube top runs through the top of mounting bracket and nut in proper order and extends to the upside of nut, just sheathed tube top fixedly connected with drives the cap.
Through adopting above-mentioned technical scheme, through setting up the nut after first connecting band and second connecting band elasticity regulation are good, can carry on spacingly to the winding axle through the external screw thread and the nut cooperation threaded connection on sleeve pipe surface.
Further, the sliding grooves are formed in the two sides of the inner wall of the sleeve, and sliding blocks are fixedly connected to the two sides of the surface of the winding shaft.
Through adopting above-mentioned technical scheme, when the transmission sleeve pipe, can drive the winding axle and follow the rotation through slider cooperation spout to the sleeve pipe can slide winding axle relatively.
Further, the lower side of the sleeve surface is provided with an external thread.
In summary, the invention mainly has the following beneficial effects:
firstly, a blood sugar change curve is generated through an electronic transmission module, medical staff can pay attention to the blood sugar condition of a patient in real time in the whole glucose load and insulin injection process according to the blood sugar change curve, a certain dose of insulin is given when the blood sugar load and the insulin injection process are obviously increased to be larger than a threshold value, then an imaging agent is injected when the slope of a blood sugar descending curve is maximum, the glucose uptake of the living cardiac muscle is mobilized to the maximum extent, the image quality is improved, and the pain and the uncomfortable feeling of the patient who measures the blood sugar for many times in a short time can be avoided;
and through the threshold value comparison module, when the patient has hypoglycemia, namely the blood sugar value is lower than the set threshold value, the alarm module is triggered to inform medical personnel to process, so that serious consequences are avoided.
Drawings
FIG. 1 is a schematic structural diagram of a first embodiment of the present invention;
FIG. 2 is a schematic structural diagram of a first embodiment of the present invention;
FIG. 3 is a schematic view of the internal structure of the portion shown in FIG. 2 according to the present invention;
FIG. 4 is a cross-sectional view of the rotation limiting member of FIG. 2 according to the present invention;
FIG. 5 is a cross-sectional view of the slack adjuster of FIG. 2 in accordance with the present invention;
FIG. 6 is a side view of the stationary shaft of FIG. 2 in accordance with the present invention;
FIG. 7 is a side view of the arcuate block of FIG. 2 in accordance with the present invention;
FIG. 8 is a photograph of sugar-mixing success using the present invention;
fig. 9 is a photograph of a sugar adjustment failure without the use of the present invention.
In the figure: 1. a glucometer body; 2. rotating the limiting piece; 21. a fixed block; 22. a fixed shaft; 23. a fixed pipe 24 and a limit groove; 25. a clamping block; 26. an adjustment groove; 27. an elastic member; 28. an arc-shaped block; 29. positioning a rod; 210. a stopper; 3. a sealing cover; 4. a first connecting belt; 5. a second connecting band; 6. a tightness adjusting device; 61. a mounting frame; 62. a winding shaft; 63. nut, 64, sleeve; 65. a slider; 66. a chute; 67. the cap is driven; 68. and (4) external threads.
Detailed Description
The present invention is described in further detail below with reference to figures 1-7.
An intelligent device for monitoring blood sugar by glucose regulation through 18F-FDG PET survival myocardial imaging, as shown in figure 1, comprises: the information acquisition module: the information acquisition module is used for acquiring blood sugar information of a detected person;
the electronic transmission module is used for generating a blood glucose change curve for the collected blood glucose information of the examinee;
the display module displays the blood sugar change curve generated by the electronic transmission module;
a threshold comparison module that sets a risk threshold for hypoglycemia of the subject and compares a lowest blood glucose value of the subject with the threshold;
the alarm module alarms when the threshold comparison module detects that the blood sugar value of the checked person is lower than the threshold;
and the output end of the main control module is electrically connected with the input ends of the information acquisition module, the electronic transmission module and the threshold comparison module respectively.
Preferably, as shown in fig. 1, an output end of the threshold comparison module is electrically connected to an input end of the alarm module, and the electronic transmission module is electrically connected to an input end of the display module.
The threshold value is a dangerous critical value of hypoglycemia of a human body, and the alarm module reminds through voice and flash cooperation.
The using method comprises the following steps: firstly, acquiring blood sugar information of a patient through an information acquisition module in blood sugar detection equipment, generating a blood sugar-time change curve through an electronic transmission module, and paying attention to the blood sugar condition of the patient in real time in the whole glucose load process according to the blood sugar change curve by medical care, and giving a certain dose of insulin when the blood sugar condition is obviously increased to be larger than a threshold value;
then injecting developer when the slope of the blood sugar descending curve is maximum, and mobilizing the living cardiac muscle to take glucose to the maximum extent, thereby improving the image quality;
and through threshold value contrast module, when the patient takes place hypoglycemia, when the blood sugar value is less than the threshold value that sets up promptly, touch alarm module, inform medical care to handle, avoid causing serious consequence, and the device can avoid patient's pain and the uncomfortable sense that blood sugar was pricked many times in the short time.
Second embodiment
Referring to fig. 2, fig. 3 and fig. 5 in combination, based on the intelligent device for monitoring blood glucose for imaging and glucose-regulating 18F-FDG PET viable myocardium provided in the first embodiment of the present application, the second embodiment of the present application provides another intelligent device for monitoring blood glucose for imaging and glucose-regulating 18F-FDG PET viable myocardium. The second embodiment is only the preferred mode of the first embodiment, and the implementation of the second embodiment does not affect the implementation of the first embodiment alone.
Specifically, the difference that the 18F-FDG PET cardiac muscle imaging is survived and is transferred sugared blood glucose monitoring intelligent device that uses that the second embodiment of this application provided lies in, and the 18F-FDG PET cardiac muscle imaging is survived and is transferred sugared blood glucose monitoring intelligent device that uses still includes blood glucose meter main part 1, information acquisition module, electron transmission module, display module, threshold value contrast module, alarm module and main control module all set up in on the blood glucose meter main part 1, one side of blood glucose meter main part 1 is through rotating 2 fixedly connected with seal cover 3 of locating part.
Preferably, as shown in fig. 2, 3, 4, 6 and 7, the rotation limiting member 2 includes two fixing blocks 21, the two fixing blocks 21 are symmetrically fixed to one side of the blood glucose meter main body 1, a fixing shaft 22 is fixedly connected between the two fixing blocks 21, a fixing tube 23 is sleeved on a surface of the fixing shaft 22, and the sealing cover 3 is fixed to one side of a surface of the fixing tube 23.
The fixed tube 23 is rotatable relative to the fixed shaft 22, and a driving block is fixed to the back surface of the seal cover 3.
Preferably, as shown in fig. 2, 3, 4, 6 and 7, an adjusting groove 26 is symmetrically formed on one side of the inner surface of the fixed tube 23, an arc-shaped block 28 is fixedly connected to one side of the inner wall of the adjusting groove 26 through an elastic member 27, a stopper 210 is symmetrically and fixedly connected to the other side of the inner surface of the fixed tube 23, two limiting grooves 24 are formed on both sides of the surface of the fixed shaft 22, and the two limiting grooves 24 and the axis of the fixed shaft 22 are arranged at an angle of one hundred eighty degrees.
The inner surface of the arc block 28 and the surface of the fixing shaft 22 are both smooth surfaces, and the distance between the two clamping blocks 25 is the same as the distance between the two limiting grooves 24.
Preferably, as shown in fig. 2, fig. 3, fig. 4, fig. 6 and fig. 7, positioning rods 29 are fixedly connected to both sides of the bottom of the arc-shaped surface of the arc-shaped block 28, positioning holes are respectively formed in both sides of the bottom of the inner wall of the fixed tube 23 and located on the arc-shaped block 28, and a stopper 210 is fixedly connected to one side of the two fixed blocks 21 opposite to the rear side of the fixed tube 23.
One end of the positioning rod 29 extends to the inside of the positioning hole.
Preferably, as shown in fig. 2, fig. 3 and fig. 5, the two sides of the blood glucose meter main body 1 are respectively and fixedly connected with a first connecting belt 4 and a second connecting belt 5, one end of the second connecting belt 5 is fixedly connected with a tightness adjusting device 6, the tightness adjusting device 6 comprises a mounting frame 61, one side of the inner wall of the mounting frame 61 is rotatably connected with a winding shaft 62, and one end of the first connecting belt 4 is fixedly connected with the winding shaft 62.
Preferably, as shown in fig. 2, 3 and 5, a sleeve 64 is slidably connected to the top of the winding shaft 62, a nut 63 is fixedly connected to the top of the mounting bracket 61, the top end of the sleeve 64 sequentially penetrates through the top of the mounting bracket 61 and the nut 63 and extends to the upper side of the nut 63, and a driving cap 67 is fixedly connected to the top end of the sleeve 64.
The upper side of the sleeve 64 is smaller in diameter than the lower side.
Preferably, as shown in fig. 2, 3 and 5, sliding grooves 66 are formed on both sides of the inner wall of the sleeve 64, and sliding blocks 65 are fixedly connected to both sides of the surface of the winding shaft 62.
The slide block 65 is located inside the slide groove 66, and the slide block 65 and the slide groove 66 cooperate to form a sliding connection between the winding shaft 62 and the sleeve 64.
Preferably, as shown in FIGS. 1, 2 and 3, the underside of the surface of the sleeve 64 is provided with external threads 68.
The external thread 68 is adapted to the nut 63.
When the blood glucose meter main body 1 is used by a subject to detect blood glucose, the subject can sleeve the blood glucose meter on the arm, then the driving cap 67 is twisted clockwise to drive the cap 67 to drive the winding shaft 62 to rotate, so that the first connecting belt 4 is wound and gradually tightened, and when the tightening is approached, the driving cap 67 can be pulled upwards to enable the external thread 68 on the surface of the sleeve 64 to correspond to the position of the nut 63, then the twisting is continued to enable the sleeve 64 to be in threaded connection with the nut 63, so that the winding shaft 62 can be limited, meanwhile, the first connecting belt 4 and the second connecting belt 5 are tightened, when the blood glucose meter is disassembled, the first connecting belt 4 is loosened through reverse rotation, and then the blood glucose meter can be taken down;
through this elasticity adjusting device, can make first connecting band 4 and second connecting band 5 adjust to the position with wearer's arm looks adaptation, can not appear the problem of tension or too loose, and easy operation.
When the glucometer main body 1 is used, the sealing cover 3 is pulled outwards, the sealing cover 3 pulls the fixing tube 23, the fixing tube 23 moves upwards, the elastic piece 27 is compressed by the fixing shaft 22, and the clamping block 25 moves out of the limiting groove 24;
at the moment, the sealing cover 3 can be rotated to be incapable of rotating, the sealing cover 3 is contacted with the stop block 210, namely, the sealing cover is rotated by one hundred eighty degrees, the clamping block 25 corresponds to the limiting groove 24 on the other side, the sealing cover 3 is loosened, the clamping block 25 is pushed into the limiting groove 24 through the action of the elastic piece 27 to limit the limiting groove 24, and the operation is simple;
when not using, with the same principle outside pulling sealed cowling 3, then rotate one hundred eighty degrees and seal the induction zone of blood glucose meter main part 1, prevent that foreign matter such as dust from the adhesion at the induction zone, influence the detection accuracy, improve blood glucose meter main part 1's life simultaneously.
The parts not involved in the present invention are the same as or can be implemented by the prior art.
The present embodiment is only for explaining the present invention, and it is not limited to the present invention, and those skilled in the art can make modifications of the present embodiment without inventive contribution as needed after reading the present specification, but all of them are protected by patent law within the scope of the claims of the present invention.
Claims (10)
1. An intelligent device for monitoring blood sugar by developing and glucose-regulating 18F-FDG PET surviving myocardium, which is characterized by comprising: the information acquisition module: the information acquisition module is used for acquiring blood sugar information of a detected person;
the electronic transmission module is used for generating a blood glucose change curve for the collected blood glucose information of the examinee;
the display module displays the blood sugar change curve generated by the electronic transmission module;
a threshold comparison module that sets a risk threshold for hypoglycemia of the subject and compares a lowest blood glucose value of the subject with the threshold;
the alarm module alarms when the threshold comparison module detects that the blood sugar value of the checked person is lower than the threshold;
and the output end of the main control module is electrically connected with the input ends of the information acquisition module, the electronic transmission module and the threshold comparison module respectively.
2. The intelligent 18F-FDG PET glucose monitoring device for viable myocardium imaging and glucose regulation according to claim 1, wherein: the output end of the threshold comparison module is electrically connected with the input end of the alarm module, and the electronic transmission module is electrically connected with the input end of the display module.
3. The intelligent 18F-FDG PET glucose monitoring device for viable myocardium imaging and glucose regulation according to claim 1, wherein: still include blood glucose meter main part (1), information acquisition module, electron transmission module, display module, threshold value contrast module, alarm module and main control module all set up in on the blood glucose meter main part (1), one side of blood glucose meter main part (1) is through rotating locating part (2) fixedly connected with sealed cowling (3).
4. The intelligent 18F-FDG PET glucose monitoring device for viable myocardium imaging and glucose regulation according to claim 3, wherein: rotate locating part (2) and include two fixed blocks (21), two fixed block (21) symmetry is fixed in one side of blood glucose meter main part (1), two fixedly connected with fixed axle (22) between fixed block (21), the surface cover of fixed axle (22) is equipped with fixed pipe (23), sealed cowling (3) are fixed in one side on fixed pipe (23) surface.
5. The intelligent 18F-FDG PET glucose monitoring device for viable myocardium imaging and glucose regulation according to claim 4, wherein: adjustment tank (26) have been seted up to one side symmetry of fixed pipe (23) internal surface, elastic component (27) fixedly connected with arc piece (28) are passed through to one side of adjustment tank (26) inner wall, the opposite side symmetry fixedly connected with dog (210) of fixed pipe (23) internal surface, two spacing groove (24), two have all been seted up to the both sides on fixed axle (22) surface spacing groove (24) are one hundred eighty degrees settings with the axle center of fixed axle (22).
6. The intelligent 18F-FDG PET glucose monitoring device for viable myocardium imaging and glucose regulation according to claim 5, wherein: the equal fixedly connected with locating lever (29) in both sides of arc piece (28) arcwall face bottom, the locating hole has all been seted up to fixed pipe (23) inner wall bottom and the both sides that are located arc piece (28), two one side that fixed block (21) is relative just is located rear side fixedly connected with dog (210) of fixed pipe (23).
7. The intelligent 18F-FDG PET glucose monitoring device for viable myocardium imaging and glucose regulation according to claim 3, wherein: the utility model discloses a blood glucose meter, including blood glucose meter main part (1), the both sides of blood glucose meter main part (1) are the first connecting band of fixedly connected with (4) and second connecting band (5) respectively, the one end fixedly connected with tight regulation device (6) of second connecting band (5), tight regulation device (6) are including mounting bracket (61), one side of mounting bracket (61) inner wall is rotated and is connected with winding axle (62), the one end of first connecting band (4) with winding axle (62) fixed connection.
8. The intelligent 18F-FDG PET glucose monitoring device for viable myocardium imaging and glucose regulation according to claim 7, wherein: the top sliding connection of winding axle (62) has sleeve pipe (64), the top fixedly connected with nut (63) of mounting bracket (61), the top of sleeve pipe (64) runs through the top of mounting bracket (61) and nut (63) in proper order and extends to the upside of nut (63), just the top fixedly connected with of sleeve pipe (64) drives cap (67).
9. The intelligent 18F-FDG PET glucose monitoring device for viable myocardium imaging and glucose regulation according to claim 8, wherein: the both sides on sleeve pipe (64) inner wall have all been seted up spout (66), the equal fixedly connected with slider (65) in both sides on winding axle (62) surface.
10. The intelligent 18F-FDG PET glucose monitoring device for viable myocardium imaging and glucose regulation according to claim 5, wherein: the underside of the surface of the sleeve (64) is provided with external threads (68).
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