CN111701138A - Multifunctional catheter and preparation method thereof - Google Patents
Multifunctional catheter and preparation method thereof Download PDFInfo
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- CN111701138A CN111701138A CN202010473657.5A CN202010473657A CN111701138A CN 111701138 A CN111701138 A CN 111701138A CN 202010473657 A CN202010473657 A CN 202010473657A CN 111701138 A CN111701138 A CN 111701138A
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- 238000002360 preparation method Methods 0.000 title abstract description 5
- 239000002131 composite material Substances 0.000 claims abstract description 36
- 210000004185 liver Anatomy 0.000 claims abstract description 15
- 239000008280 blood Substances 0.000 claims abstract description 12
- 210000004369 blood Anatomy 0.000 claims abstract description 12
- 238000002054 transplantation Methods 0.000 claims abstract description 12
- 238000000034 method Methods 0.000 claims abstract description 11
- 238000005491 wire drawing Methods 0.000 claims abstract description 11
- 230000000250 revascularization Effects 0.000 claims abstract description 8
- 238000003466 welding Methods 0.000 claims description 21
- 239000000463 material Substances 0.000 claims description 19
- 210000004204 blood vessel Anatomy 0.000 claims description 13
- 238000009941 weaving Methods 0.000 claims description 11
- 238000005452 bending Methods 0.000 claims description 10
- 230000004087 circulation Effects 0.000 claims description 9
- 230000017531 blood circulation Effects 0.000 claims description 8
- 239000004810 polytetrafluoroethylene Substances 0.000 claims description 8
- 229920001343 polytetrafluoroethylene Polymers 0.000 claims description 8
- 229920002614 Polyether block amide Polymers 0.000 claims description 6
- 238000007664 blowing Methods 0.000 claims description 5
- 238000004804 winding Methods 0.000 claims description 5
- 229920002635 polyurethane Polymers 0.000 claims description 4
- 239000004814 polyurethane Substances 0.000 claims description 4
- 210000001105 femoral artery Anatomy 0.000 claims description 3
- 210000003191 femoral vein Anatomy 0.000 claims description 3
- 230000004927 fusion Effects 0.000 claims description 3
- 210000005077 saccule Anatomy 0.000 claims description 3
- 238000001746 injection moulding Methods 0.000 claims description 2
- 229910001220 stainless steel Inorganic materials 0.000 claims description 2
- 239000010935 stainless steel Substances 0.000 claims description 2
- 239000000243 solution Substances 0.000 description 5
- 230000000694 effects Effects 0.000 description 4
- 210000005228 liver tissue Anatomy 0.000 description 4
- 239000002184 metal Substances 0.000 description 4
- 230000001154 acute effect Effects 0.000 description 3
- 238000013461 design Methods 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 206010057573 Chronic hepatic failure Diseases 0.000 description 1
- 208000010334 End Stage Liver Disease Diseases 0.000 description 1
- 208000032843 Hemorrhage Diseases 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 208000011444 chronic liver failure Diseases 0.000 description 1
- 238000012377 drug delivery Methods 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 230000000149 penetrating effect Effects 0.000 description 1
- 238000007674 radiofrequency ablation Methods 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 238000012546 transfer Methods 0.000 description 1
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/10—Balloon catheters
- A61M25/1002—Balloon catheters characterised by balloon shape
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/12—Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
- A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
- A61B17/12099—Occluding by internal devices, e.g. balloons or releasable wires characterised by the location of the occluder
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/12—Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
- A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
- A61B17/12131—Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device
- A61B17/12136—Balloons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/0043—Catheters; Hollow probes characterised by structural features
- A61M25/0045—Catheters; Hollow probes characterised by structural features multi-layered, e.g. coated
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/10—Balloon catheters
- A61M25/1025—Connections between catheter tubes and inflation tubes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/10—Balloon catheters
- A61M25/1027—Making of balloon catheters
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C69/00—Combinations of shaping techniques not provided for in a single one of main groups B29C39/00 - B29C67/00, e.g. associations of moulding and joining techniques; Apparatus therefore
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2207/00—Methods of manufacture, assembly or production
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- Heart & Thoracic Surgery (AREA)
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Abstract
The problem of among the liver transplantation process blood loss in a large number it does not have equipment to assist and carries out the revascularization is solved, a multi-functional pipe and preparation method are provided, a multi-functional pipe, its characterized in that includes: the composite braided tube comprises a multilayer composite braided tube, a TPU tube, a balloon, a handle joint, a wiredrawing and a fixing ring, wherein one end of the multilayer composite braided tube is fixedly connected with one end of the TPU tube, the fixing ring is fixed at the other end of the multilayer composite braided tube and is fixedly connected with the wiredrawing and further connected with the handle joint, the handle joint is fixed at the other end of the TPU tube, and the balloon is fixed on one side of the multilayer composite braided tube fixing ring.
Description
Technical Field
The invention relates to the field of medical instruments, in particular to a multifunctional catheter and a preparation method thereof.
Background
Liver transplantation has become a conventional treatment for end-stage liver diseases, and how to reduce blood loss and revascularization of patients during liver transplantation is a research direction of major attention by those skilled in the art.
At present, liver transplantation is mainly carried out in several ways, one is traditional operation, namely liver tissue is subjected to open excision, and a great amount of blood loss is inevitably generated in the operation process; the other is extracorporeal circulation technology, in which blood vessels are connected to catheters for extracorporeal circulation of blood, but the extracorporeal circulation also causes a great loss of blood during the operation.
The inventor thinks that if the catheter technology is applied to the liver transplantation operation, the plugging of the blood vessel can be completed by the minimally invasive operation, and the catheter has the function of the revascularization, and the problem of massive hemorrhage of the patient in the operation process can be solved, but the current adjustable bent sheath tube is mainly used for minimally invasive drug delivery and radio frequency ablation and does not have the functions of the plugging of the blood vessel transplanted in the liver and the revascularization.
Disclosure of Invention
The invention solves the problem that a large amount of blood is lost in the liver transplantation process and the blood transportation reconstruction is carried out without the assistance of equipment, and provides a multifunctional catheter and a preparation method thereof.
According to a first aspect of the present invention, there is provided a multifunctional catheter characterized by comprising: the composite braided tube comprises a multilayer composite braided tube, a TPU tube, a balloon, a handle joint, a wiredrawing and a fixing ring, wherein one end of the multilayer composite braided tube is fixedly connected with one end of the TPU tube, the fixing ring is fixed at the other end of the multilayer composite braided tube and is fixedly connected with the wiredrawing and further connected with the handle joint, the handle joint is fixed at the other end of the TPU tube, and the balloon is fixed on one side of the multilayer composite braided tube fixing ring.
Further, the multilayer composite braided tube has three layers: the inner layer is extruded by PTFE, the inner diameter is 1-5mm, and the thickness is 0.1-0.5 mm; the middle layer is formed by weaving stainless steel winding, and the thickness is 0.05-2 mm; the outer layer is formed by extruding a Pebax material, the inner diameter is 1.5-8mm, and the thickness is 0.05-0.5 mm.
Further, the TPU pipe is obtained by extruding a polyurethane material, wherein the hardness of the TPU is 80A-65D, and the thickness of the TPU is 0.1-2 mm.
Further, the fixed connection mode of the multilayer composite braided tube and the TPU tube is axial welding, the welding temperature is 150-; the fixing mode of the fixing ring and the wire drawing is fusion welding; the handle joint and the TPU pipe are fixed in a light fixing and bonding mode, and the light curing wavelength is 220-250 nm; the fixing mode of the saccule is welding.
Furthermore, the expansion diameter of the balloon is 2-50mm, the volume of the balloon is 0.5-20ml, and the thickness of the balloon is 0.05-0.3 mm.
Further, the handle joint include that the sacculus is full of mouthful, the blood transport rebuilds connector, transfer curved structure with the wire drawing link to each other.
Further, the TPU tube is 10-50mm long and is a TPU double-cavity tube, and comprises a TPU outer tube and a TPU inner tube, the TPU outer tube is used for balloon inflation, the TPU inner tube is used for blood flow to pass through, a cavity is additionally arranged between the outer layer and the inner layer of the multilayer composite braided tube to form the multilayer composite braided double-cavity tube, and the TPU double-cavity tube and the two cavities of the multilayer composite braided double-cavity tube are consistent in size and are fixedly connected together.
Furthermore, the bending adjusting structure controls the adjusting angle to be 20-180 degrees, and the bending adjusting distance is 10-50 mm.
Furthermore, the multifunctional catheter is applied to liver transplantation, the catheter passes through femoral artery/femoral vein and reaches the inside of a liver transplantation blood vessel through direction adjustment, the balloon is inflated to block the blood vessel for 24-28h, and the liver is taken out and then connected with an extracorporeal circulation machine to carry out blood extracorporeal circulation.
According to a second aspect of the present invention, there is provided a method of equipping a multifunctional catheter, characterized by comprising the steps of:
the method comprises the following steps: medical-grade PTFE is extruded into a catheter, the inner diameter of the catheter is 1-5mm, and the wall thickness of the catheter is 0.1-0.5 mm;
step two: putting the catheter built-in mandrel extruded in the step one into a spring machine for winding and weaving;
step three: extruding medical-grade Pebax material to form a catheter, sleeving the catheter outside the finished product obtained in the second step, and performing thermal shrinkage treatment, wherein the catheter is designed into a double-cavity tube, the inner diameter of the double-cavity tube is 1.5-8mm, the wall thickness of the double-cavity tube is 0.05-0.5mm, and the multilayer composite catheter is obtained through the first step to the third step;
step four: extruding a catheter by using medical grade TPU, wherein the hardness of the TPU is 80A-65D, the TPU material is polyurethane and is extruded into a double-cavity tube, and the inner diameter of the inner tube is 1-10 mm;
step five: axially welding the TPU pipe and the inner and outer cavities of the multilayer composite conduit, wherein the temperature of a welding machine is 150-200 ℃, and the welding time is 30-200 s;
step six: designing a handle joint, and bonding the handle joint with the TPU pipe in a light fixing bonding mode through injection molding, wherein the light curing wavelength is 220-250nm, and the length is 10-50 mm;
and 7: blowing a balloon by using a TPU material, and welding the balloon and the multilayer composite catheter, wherein the diameter of the balloon is 2-50mm, the volume of the balloon is 0.5-20ml, and the thickness of the balloon is 0.05-0.3 mm;
and 8: the fixing ring is fixed on one side of the multilayer composite conduit, and the wire drawing is fixedly connected on the fixing ring and is connected to the handle joint.
The invention has the beneficial effects that: the multifunctional composite catheter can be directly used in a liver transplantation blood vessel, is bent into the liver transplantation blood vessel through a femoral artery or a femoral vein, promotes the blood vessel to be blocked for 24-48 hours by utilizing the expansion of the saccule, is connected with an extracorporeal circulation machine to carry out extracorporeal circulation of blood after liver tissues are taken out, greatly reduces the blood loss in the operation process and can be used for revascularization.
Drawings
In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings used in the description of the embodiments or the prior art will be briefly described below, it is obvious that the drawings in the following description are only embodiments of the present invention, and for those skilled in the art, other drawings can be obtained according to the provided drawings without creative efforts.
FIG. 1 is a schematic view of the overall structure of the multifunctional catheter of the present invention;
FIG. 2 is a schematic view of a balloon end structure of the multifunctional catheter of the present invention;
FIG. 3 is a schematic view of the structure of the handle adapter in the multifunctional catheter of the present invention;
FIG. 4 is a schematic view of the multi-functional catheter of the present invention in use in a blood vessel;
fig. 5 is a schematic view of the multifunctional catheter bending adjustment of the present invention.
The specific figures are illustrated as follows:
1-a fixed ring; 2-a balloon; 3-balloon filling port; 4-revascularization connector; 5-bending adjusting structure.
Detailed Description
In order to make the technical solutions of the present invention better understood, the technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be obtained by a person skilled in the art without any inventive step based on the embodiments of the present invention, shall fall within the scope of the present invention.
Example 1:
the assembled multifunctional catheter is manufactured and the bending angle and the blood flow speed are verified according to the following steps:
s1: selecting a PTFE extruded catheter with the inner diameter of 2mm and the outer diameter of 2.5mm and the length of 1m for later use;
s2: a core shaft with the outer diameter of 1.98mm penetrates into the PTFE catheter and is placed in a weaving machine for weaving, and the thickness of a weaving wire is 0.1 mm;
s3: selecting a Pebax material with the hardness of 50D to extrude a catheter with the inner diameter of 2.7mm and the outer diameter of 3.5mm, and a hole with the diameter of 0.3mm is arranged to penetrate into a metal wire catheter which is just woven;
s4: putting the catheter with the woven wire into a thermal shrinkage machine for thermal shrinkage, wherein the thermal shrinkage temperature is 180 ℃ and the thermal shrinkage speed is 50 mm/min;
s5: selecting a TPU material with the hardness of 50D to extrude a catheter with the inner diameter of 2mm, the outer diameter of 3.5mm, the inner diameter of 0.3mm and the length of 50 mm;
s6: selecting a TPU material with the hardness of 80A, setting the temperature to be 150 ℃, and blowing the pressure to be 5atm to blow a balloon with the length of 10mm and the diameter of 10 mm;
s7: the balloon and the TPU double-cavity tube are welded at the temperature of 170 ℃ for 60s, and the outer end of the double-cavity tube and the balloon need to be perforated;
s8: the PP material is injected into a hard pipe with the length of 3mm, the inner diameter of 2.6mm and the outer diameter of 3.5mm and is welded with a metal wire with the diameter of 0.1mm, and the welding temperature is 180 ℃;
s9: the acute welding temperature of the prepared PP pipe and the distal end of the TPU catheter is 180 ℃;
s10: the design of the handle, the innermost layer of the catheter is bonded with the blood circulation joint of the handle, one cavity of the catheter is bonded with the filling opening of the handle, and the thread joint of the guide wire and the handle is assembled.
The multifunctional composite catheter prepared by the method. After the balloon is implanted into a liver tissue blood vessel, the balloon plugging effect is good, the turning effect is excellent, and the revascularization is good. The specific measured indicators are as follows:
table 1 example 1 specific parameter table
| Angle of bending | Balloon inflation volume | Velocity of blood flow |
| 45 degree | 20ml | 50ml/min |
Example 2:
the assembled multifunctional catheter is manufactured and the bending angle and the blood flow speed are verified according to the following steps:
(1) selecting a PTFE extruded catheter with the inner diameter of 2mm and the outer diameter of 2.5mm and the length of 1m for later use;
(2) a core shaft with the outer diameter of 1.98mm penetrates into the PTFE catheter and is placed in a weaving machine for weaving, and the thickness of a weaving wire is 0.1 mm;
(3) selecting a Pebax material with the hardness of 50D to extrude a catheter with the inner diameter of 2.7mm and the outer diameter of 3.5mm, and a hole with the diameter of 0.3mm is arranged to penetrate into a metal wire catheter which is just woven;
(4) putting the catheter with the woven wire into a thermal shrinkage machine for thermal shrinkage, wherein the thermal shrinkage temperature is 180 ℃ and the thermal shrinkage speed is 50 mm/min;
(5) selecting a TPU material with the hardness of 50D to extrude a catheter with the inner diameter of 2.7mm, the outer diameter of 3.5mm, the inner diameter of a cavity of 0.3mm and the length of 50 mm;
(6) selecting a TPU material with the hardness of 50D to extrude a catheter with the inner diameter of 2mm, the outer diameter of 2.5mm and the length of 50 mm;
(7) penetrating the inner diameter of the extruded catheter with the outer diameter of 2.5mm into a mandrel with the outer diameter of 0.19mm, placing weaving wires and winding;
(8) placing the guide pipe with the outer diameter of 3.5mm and the guide pipe with the outer diameter of 2.7mm into a shrinking machine for acute fusion at the temperature of 180 ℃ for 60 seconds;
(9) selecting a TPU material with the hardness of 80A, setting the temperature to be 150 ℃ and the blowing pressure to be 5atm, and blowing a balloon with the length of 10mm and the diameter of 10 mm;
(10) welding the balloon and the TPU double-cavity tube at the temperature of 170 ℃ for 60s, wherein the outer end of the double-cavity tube and the balloon need to be perforated;
(11) injecting a hard pipe with the length of 3mm, the inner diameter of 2.6mm and the outer diameter of 3.5mm by using a PP material, and welding the hard pipe with a metal wire with the diameter of 0.1mm at the welding temperature of 180 ℃;
(12) the acute welding temperature of the prepared PP pipe and the distal end of the TPU catheter is 180 ℃;
(13) the design of the handle, the innermost layer of the catheter is bonded with the blood circulation joint of the handle, one cavity of the catheter is bonded with the filling opening of the handle, and the thread joint of the guide wire and the handle is assembled.
The multifunctional composite catheter is prepared by the method. After the balloon is implanted into a liver tissue blood vessel, the balloon plugging effect is good, the turning effect is excellent, and the revascularization is good. The specific measured indicators are as follows:
table 2 example 2 specific parameter table
| Angle of bending | Balloon inflation volume | Velocity of blood flow |
| 80 degree | 20ml | 50ml/min |
The examples are given solely for the purpose of illustrating the invention and are not to be construed as limiting thereof; although the present invention has been described in detail with reference to the foregoing embodiments, it will be understood by those of ordinary skill in the art that: the technical solutions described in the foregoing embodiments may still be modified, or some technical features may be equivalently replaced; and such modifications or substitutions do not depart from the spirit and scope of the corresponding technical solutions of the embodiments of the present invention.
Claims (10)
1. A multi-functional catheter, comprising: the composite braided tube comprises a multilayer composite braided tube, a TPU tube, a balloon, a handle joint, a wiredrawing and a fixing ring, wherein one end of the multilayer composite braided tube is fixedly connected with one end of the TPU tube, the fixing ring is fixed at the other end of the multilayer composite braided tube and is fixedly connected with the wiredrawing and further connected with the handle joint, the handle joint is fixed at the other end of the TPU tube, and the balloon is fixed on one side of the multilayer composite braided tube fixing ring.
2. The multifunctional catheter as claimed in claim 1, wherein said multi-layer composite braided tube has three layers: the inner layer is extruded by PTFE, the inner diameter is 1-5mm, and the thickness is 0.1-0.5 mm; the middle layer is formed by weaving stainless steel winding, and the thickness is 0.05-2 mm; the outer layer is formed by extruding a Pebax material, the inner diameter is 1.5-8mm, and the thickness is 0.05-0.5 mm.
3. The multifunctional catheter according to claim 1, wherein said TPU tube is extruded from a polyurethane material, wherein the TPU has a hardness of 80A to 65D and a thickness of 0.1 to 2 mm.
4. The multifunctional catheter as claimed in claim 1, wherein the fixed connection between the multi-layer composite braided tube and the TPU tube is axial welding at a temperature of 150-; the fixing mode of the fixing ring and the wire drawing is fusion welding; the handle joint and the TPU pipe are fixed in a light fixing and bonding mode, and the light curing wavelength is 220-250 nm; the fixing mode of the saccule is welding.
5. The multifunctional catheter as claimed in claim 1, wherein the balloon has an inflated diameter of 2-50mm, a volume of 0.5-20ml, and a thickness of 0.05-0.3 mm.
6. The multifunctional catheter according to claim 1, wherein said handle connector comprises a balloon filling port, a revascularization connector, and a bend-adjusting structure, said bend-adjusting structure being connected to said pull wire.
7. The multifunctional catheter according to claim 1, wherein the TPU tube is 10-50mm long and is a TPU double lumen tube comprising an outer TPU tube for balloon inflation and an inner TPU tube for blood flow, a lumen is added between the outer layer and the inner layer of the multi-layer composite braided tube to form the multi-layer composite braided double lumen tube, and the TPU double lumen tube and the two lumens of the multi-layer composite braided double lumen tube are identical in size and fixedly connected together.
8. The multifunctional catheter according to claim 6, wherein the bending adjusting structure controls the adjustment angle to be 20-180 degrees and the bending adjusting distance to be 10-50 mm.
9. The multifunctional catheter as claimed in claim 1, wherein the multifunctional catheter is applied to liver transplantation, the catheter is passed through femoral artery/vein and reaches the liver transplantation blood vessel through direction adjustment, the balloon is inflated to block the blood vessel for 24-28h, and the liver is taken out and then connected with an extracorporeal circulation machine for extracorporeal circulation of blood.
10. A method of equipping a multifunctional catheter, comprising the steps of:
the method comprises the following steps: medical-grade PTFE is extruded into a catheter, the inner diameter of the catheter is 1-5mm, and the wall thickness of the catheter is 0.1-0.5 mm;
step two: putting the catheter built-in mandrel extruded in the step one into a spring machine for winding and weaving;
step three: extruding medical-grade Pebax material to form a catheter, sleeving the catheter outside the finished product obtained in the second step, and performing thermal shrinkage treatment, wherein the catheter is designed into a double-cavity tube, the inner diameter of the double-cavity tube is 1.5-8mm, the wall thickness of the double-cavity tube is 0.05-0.5mm, and the multilayer composite catheter is obtained through the first step to the third step;
step four: extruding a catheter by using medical grade TPU, wherein the hardness of the TPU is 80A-65D, the TPU material is polyurethane and is extruded into a double-cavity tube, and the inner diameter of the inner tube is 1-10 mm;
step five: axially welding the TPU pipe and the inner and outer cavities of the multilayer composite conduit, wherein the temperature of a welding machine is 150-200 ℃, and the welding time is 30-200 s;
step six: designing a handle joint, and bonding the handle joint with the TPU pipe in a light fixing bonding mode through injection molding, wherein the light curing wavelength is 220-250nm, and the length is 10-50 mm;
and 7: blowing a balloon by using a TPU material, and welding the balloon and the multilayer composite catheter, wherein the diameter of the balloon is 2-50mm, the volume of the balloon is 0.5-20ml, and the thickness of the balloon is 0.05-0.3 mm;
and 8: the fixing ring is fixed on one side of the multilayer composite conduit, and the wire drawing is fixedly connected on the fixing ring and is connected to the handle joint.
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| US20020058910A1 (en) * | 1994-10-24 | 2002-05-16 | Hermann George D. | Large-diameter introducer sheath having hemostasis valve and removable steering mechanism |
| US6726700B1 (en) * | 2000-08-21 | 2004-04-27 | Counter Clockwise, Inc. | Manipulatable delivery catheter for occlusive devices |
| US20060135961A1 (en) * | 2004-12-17 | 2006-06-22 | Biocardia, Inc. | Steerable guide catheters and methods for their use |
| US20190255292A1 (en) * | 2018-02-16 | 2019-08-22 | Oscor Inc. | Deflectable sheath with inflatable balloon |
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2020
- 2020-05-29 CN CN202010473657.5A patent/CN111701138A/en active Pending
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| US20020058910A1 (en) * | 1994-10-24 | 2002-05-16 | Hermann George D. | Large-diameter introducer sheath having hemostasis valve and removable steering mechanism |
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