CN111419239B - Blood amino acid and carnitine quantitative determination device based on electromagnetic control - Google Patents
Blood amino acid and carnitine quantitative determination device based on electromagnetic control Download PDFInfo
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- CN111419239B CN111419239B CN202010293211.4A CN202010293211A CN111419239B CN 111419239 B CN111419239 B CN 111419239B CN 202010293211 A CN202010293211 A CN 202010293211A CN 111419239 B CN111419239 B CN 111419239B
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
- A61B5/14503—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue invasive, e.g. introduced into the body by a catheter or needle or using implanted sensors
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
- A61B5/14546—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue for measuring analytes not otherwise provided for, e.g. ions, cytochromes
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
- A61B5/6846—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive
- A61B5/6847—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive mounted on an invasive device
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/74—Details of notification to user or communication with user or patient ; user input means
- A61B5/742—Details of notification to user or communication with user or patient ; user input means using visual displays
Abstract
A blood amino acid and carnitine quantitative detection device based on electromagnetic control relates to a blood amino acid and carnitine detection device, and aims to comprehensively detect the information of amino acid and carnitine in blood at different positions of a human body in real time. The blood robot is positioned in a venous blood vessel of a human body, and the electromagnetic drive control module, the blood information acquisition module and the blood information monitoring module are arranged in a flat space; the blood information acquisition module is connected with the blood information monitoring module through a digital signal line; the blood robot is used for quantitatively detecting amino acids and carnitine in blood at different positions of a human body; the electromagnetic drive control module is used for controlling the movement and detection process of the blood robot; the blood information acquisition module is used for acquiring signals about blood information sent by the blood robot; the blood information monitoring module is used for the scientific research personnel to visually observe the blood information of the target patient in real time; the invention is suitable for real-time quantitative detection of important blood information such as amino acid, carnitine and the like in human blood.
Description
Technical Field
The invention relates to the field of blood amino acid and carnitine detection, in particular to a blood amino acid and carnitine quantitative detection device based on electromagnetic control.
Background
In the detection process of genetic metabolic diseases such as phenylketonuria and the like, in-vitro blood detection methods such as a bacterial inhibition method and the like are generally adopted, and the in-vitro detection method can only obtain blood information of a patient at the time of detection, but is difficult to comprehensively obtain the blood information and the change rule of the patient all day long. Because human blood has the characteristic of circulatory metabolism, the content of blood components at different positions of a human body is changed, in addition, the detection of amino acid and carnitine in the blood by a bacterial inhibition method needs a long time, and more human factors exist in the detection process. The device for quantitatively detecting amino acid and carnitine in human blood based on the electromagnetic control technology comprehensively detects the information of the amino acid and the carnitine in the blood at different positions of a human body in a mode of electromagnetically driving the blood robot, and acquires the information of the amino acid and the carnitine in the blood of the human body in real time according to the information fed back by the blood robot, so that the completeness of the detected information of the amino acid and the carnitine in the blood and the high efficiency of acquiring the information are greatly met. At present, no mature device is available for real-time comprehensive detection of quantitative detection of amino acids and carnitine in human blood. Therefore, the research of the electromagnetic control-based quantitative detection device for the amino acid and the carnitine in the blood has important scientific significance for the quantitative detection of the amino acid and the carnitine in the human blood.
Disclosure of Invention
Based on the existing problems, the invention aims to provide a quantitative detection device for blood amino acid and carnitine based on electromagnetic control, so as to solve the problem that the conventional bacteria inhibition method is difficult to obtain the blood information and the change rule of the blood information of a patient all day long.
The embodiment of the invention discloses a blood amino acid and carnitine quantitative detection device based on electromagnetic control, which comprises: the blood robot comprises a blood robot 1, an electromagnetic drive control module 2, a blood information acquisition module 3 and a blood information monitoring module 4, wherein the blood robot 1 is positioned in a venous blood vessel of a human body, the electromagnetic drive control module 2, the blood information acquisition module 3 and the blood information monitoring module 4 are arranged in a flat space, and the blood information acquisition module 3 and the blood information monitoring module 4 are connected through a digital signal wire;
preferably, the blood robot 1 comprises a motion control loop 1-1, a control loop connecting unit 1-2, a blood information emitter 1-3 and a blood information processor 1-4 which are connected in sequence, and also comprises an amino acid collector 1-5 and a carnitine collector 1-6 which are connected with the bottom end of the blood information processor 1-4;
preferably, the earth electromagnetic drive control module 2 comprises an electromagnetic drive controller support 2-1 provided with an inner ring, an electromagnetic drive controller 2-3 arranged on the inner ring of the electromagnetic drive controller support 2-1, a blood robot detector 2-2 arranged at the top end of the inner ring of the electromagnetic drive controller support 2-1, an electromagnetic drive control bed 2-4, an electromagnetic drive control bed lifting frame 2-5 and an electromagnetic drive control bed sliding base 2-6 which are sequentially connected;
preferably, the blood information acquisition module 3 comprises a blood information acquisition module bracket 3-5 provided with a mechanical interface, a blood robot signal receiver 3-1 arranged on the mechanical interface of the blood information acquisition module bracket 3-5, a blood robot signal processor 3-2 arranged on the mechanical interface of the blood information acquisition module bracket 3-5, an amino acid information display 3-3 arranged at the top end of the blood information acquisition module bracket 3-5 and a carnitine information display 3-4 arranged at the top end of the blood information acquisition module bracket 3-5;
preferably, the blood information monitoring module 4 comprises a blood information monitoring industrial personal computer 4-3 provided with a signal line interface, an amino acid real-time result display 4-1 arranged on the signal line interface of the blood information monitoring industrial personal computer 4-3 and a carnitine real-time result display 4-2 arranged on the signal line interface of the blood information monitoring industrial personal computer 4-3.
The blood robot 1 is preferably driven electromagnetically.
Preferably, the blood robot 1 is in a vertical type, and the control ring connection unit 1-2, the blood information transmitter 1-3 and the blood information processor 1-4 are in a columnar structure.
Preferably, the motion control ring 1-1 is in the form of a semicircular ring structure, and the number of the semicircular ring structures is 3.
Preferably, the bottom materials of the amino acid collector 1-5 and the carnitine collector 1-6 are memory alloy materials.
Preferably, the blood robot detector 2-2 is connected with the top end of the inner ring of the electromagnetic drive controller bracket 2-1 to detect the position information of the blood robot 1.
Preferably, the earth electromagnetic driving controller 2-3 is connected with the inner ring of the electromagnetic driving controller bracket 2-1 to realize the driving control of the motion process of the blood robot 1.
Preferably, the electromagnetic drive control bed 2-4, the electromagnetic drive control bed lifting frame 2-5 and the electromagnetic drive control bed sliding base 2-6 are sequentially connected, so that the electromagnetic drive control bed 2-4 can move along the horizontal direction and the vertical direction.
Preferably, the blood robot signal receiver 3-1, the blood robot signal processor 3-2 and the blood information monitoring industrial personal computer 4-3 adopt industrial computers.
The embodiment of the invention discloses a blood amino acid and carnitine quantitative detection device based on electromagnetic control, which has the following beneficial effects:
1. the blood robot enters a human body in a intravenous injection mode, the motion control ring is arranged at the front end of the blood robot, the blood robot slowly moves inside a blood vessel of the human body to gradually reach different parts of the human body under the electromagnetic driving action of the electromagnetic driving control module, the amino acid collector and the carnitine collector positioned at the bottom end of the blood robot carry out quantitative detection on amino acid and carnitine in the blood of the human body, after the amino acid and carnitine are processed by the blood information processor of the blood robot, blood information is transmitted to the blood information acquisition module through the blood information transmitter positioned in the middle section of the blood robot, the blood information acquisition module carries out rapid processing on the obtained blood information and transmits the obtained blood detection result to the blood information monitoring module, and the requirements of comprehensiveness and instantaneity in detection of the amino acid and carnitine quantitative detection device are met.
2. The position information of the blood robot is obtained through the blood robot detector of the electromagnetic drive control module, the movement of the blood robot is realized through the electromagnetic drive controller of the electromagnetic drive control module, and the position information of the blood robot and the driving of the movement process both adopt a non-contact mode, so that uncertain injury to a patient caused by manual contact can be avoided.
3. The electromagnetic drive controllers of the electromagnetic drive control module are 1 group in number, and the economic and environmental protection requirements of the amino acid and carnitine quantitative detection device are met.
4. The movement of the electromagnetic drive control bed is realized by coupling the vertical movement of the electromagnetic drive control bed lifting frame with the horizontal movement of the electromagnetic drive control bed sliding base, and the horizontal movement and the vertical movement of the electromagnetic drive control bed are independent from each other, so that the requirements on movement stability and precision are met;
5. the blood robot signal receiver, the blood robot signal processor and the blood information monitoring industrial personal computer all adopt industrial computers, and meet the stability requirement of the work of the amino acid and carnitine quantitative detection device.
6. The amino acid collector and the carnitine collector can be replaced according to different blood components to be detected, and the universality of the amino acid and carnitine quantitative detection device is realized.
Drawings
In order to more clearly illustrate the technical solutions in the embodiments of the present invention, the drawings needed to be used in the description of the embodiments will be briefly introduced below, and it is obvious that the drawings in the following description are only some embodiments of the present invention, and it is obvious for those skilled in the art to obtain other drawings based on these drawings without inventive exercise.
FIG. 1 is a schematic perspective view of a device for quantitative determination of amino acids and carnitine in human blood based on electromagnetic control technology according to an embodiment of the present invention;
fig. 2 is a schematic perspective view of a blood robot according to an embodiment of the present invention;
fig. 3 is a schematic perspective view of an electromagnetic driving control module according to an embodiment of the present invention;
fig. 4 is a schematic perspective view of a blood information collection module according to an embodiment of the present invention;
fig. 5 is a schematic perspective view of a blood information monitoring module according to an embodiment of the present invention.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be obtained by a person skilled in the art without inventive efforts based on the embodiments of the present invention, shall fall within the scope of protection of the present invention. The invention is further described with reference to the following drawings and specific examples, which are not intended to be limiting.
A quantitative detection device for blood amino acid and carnitine based on electromagnetic control comprises a blood robot 1, an electromagnetic drive control module 2, a blood information acquisition module 3 and a blood information monitoring module 4, wherein the blood robot 1 is positioned in a venous blood vessel of a human body, the electromagnetic drive control module 2, the blood information acquisition module 3 and the blood information monitoring module 4 are arranged in a flat space, and the blood information acquisition module 3 and the blood information monitoring module 4 are connected through a digital signal wire;
the blood robot 1 comprises a motion control loop 1-1, a control loop connecting unit 1-2, a blood information emitter 1-3 and a blood information processor 1-4 which are connected in sequence, and also comprises an amino acid collector 1-5 and a carnitine collector 1-6 which are connected with the bottom end of the blood information processor 1-4; the electromagnetic driving control module 2 comprises an electromagnetic driving controller support 2-1 provided with an inner ring, an electromagnetic driving controller 2-3 arranged on the inner ring of the electromagnetic driving controller support 2-1, a blood robot detector 2-2 arranged at the top end of the inner ring of the electromagnetic driving controller support 2-1, and an electromagnetic driving control bed 2-4, an electromagnetic driving control bed lifting frame 2-5 and an electromagnetic driving control bed sliding base 2-6 which are sequentially connected; the blood information acquisition module 3 comprises a blood information acquisition module bracket 3-5 provided with a mechanical interface, a blood robot signal receiver 3-1 arranged on the mechanical interface of the blood information acquisition module bracket 3-5, a blood robot signal processor 3-2 arranged on the mechanical interface of the blood information acquisition module bracket 3-5, an amino acid information display 3-3 arranged at the top end of the blood information acquisition module bracket 3-5 and a carnitine information display 3-4 arranged at the top end of the blood information acquisition module bracket 3-5; the blood information monitoring module 4 comprises a blood information monitoring industrial personal computer 4-3 provided with a signal line interface, an amino acid real-time result display 4-1 arranged on the signal line interface of the blood information monitoring industrial personal computer 4-3 and a carnitine real-time result display 4-2 arranged on the signal line interface of the blood information monitoring industrial personal computer 4-3.
The invention is characterized in that a motion control ring 1-1, a control ring connecting unit 1-2, a blood information emitter 1-3 and a blood information processor 1-4 are connected in sequence. The motion control loop 1-1 transmits the motion process to the control loop connecting unit 1-2, the blood information emitter 1-3, the blood information processor 1-4, the amino acid collector 1-5 and the carnitine collector 1-6 in sequence under the driving action of the electromagnetic driving control module 2, and finally drives the blood robot 1 to move stably in blood.
The movement speed and the movement direction of the blood robot 1 can be realized by adjusting the power supply voltage and the frequency of the electromagnetic drive controller of the electromagnetic drive control module 2, and the position of the blood robot 1 can be obtained in real time by the blood robot detector of the electromagnetic drive control module 2.
According to the invention, an electromagnetic drive control bed 2-4, an electromagnetic drive control bed lifting frame 2-5 and an electromagnetic drive control bed sliding base 2-6 are sequentially connected, and the horizontal and vertical movements of the electromagnetic drive control bed lifting frame 2-5 and the electromagnetic drive control bed sliding base 2-6 are mutually superposed, so that the movement of the electromagnetic drive control bed 2-4 along the horizontal direction and the vertical direction is realized.
The blood robot signal receiver, the blood robot signal processor and the blood information monitoring industrial personal computer all adopt industrial computers, so that the processing of detection data and the real-time monitoring of a detection system are facilitated.
The working process is as follows:
the quantitative detection process of the device for quantitatively detecting amino acid and carnitine in human blood based on the electromagnetic control technology comprises the following steps: a target patient lies on an electromagnetic drive control bed 2-4 of an electromagnetic drive control module 2, horizontal and vertical motions of an electromagnetic drive control bed lifting frame 2-5 and an electromagnetic drive control bed sliding base 2-6 are mutually overlapped to realize adjustment of the spatial position of the electromagnetic drive control bed 2-4, a moving blood robot 1 enters human blood in a vein injection mode, a blood robot detector 2-2 of the electromagnetic drive control module 2 detects the position of the blood robot 1 in real time, an electromagnetic drive controller 2-3 of the electromagnetic drive control module 2 works under the driving action of power voltage, the electromagnetic drive controller 2-3 drives a motion control ring 1-1 of the blood robot 1 to generate a given motion action, the motion control ring 1-1 sequentially transmits the motion to a control ring connecting unit 1-2, a blood information emitter 1-3, a blood information processor 1-4, an amino acid collector 1-5 and a carnitine collector 1-6, and finally the motion control ring 1-1 drives the blood robot 1 to integrally move in the blood. When the blood robot 1 reaches a target position, the amino acid collector 1-5 and the carnitine collector 1-6 of the blood robot 1 respectively carry out quantitative detection on the amino acid and the carnitine in the blood, and blood information detected by the amino acid collector 1-5 and the carnitine collector 1-6 is processed by the blood information processor 1-4 and sent to the blood information collection module 3 by the blood information emitter 1-3.
The information transmission process of the device for quantitatively detecting amino acid and carnitine in human blood based on the electromagnetic control technology comprises the following steps: the blood information monitoring industrial personal computer 4-3 decodes the blood information and displays the detected amino acid result and the carnitine result to scientific research personnel through the amino acid real-time result display 4-1 and the carnitine real-time result display 4-2 respectively.
The above-mentioned serial numbers of the embodiments of the present invention are only for description, and do not represent the advantages and disadvantages of the embodiments.
It will be apparent to those skilled in the art that various changes and modifications may be made in the present invention without departing from the spirit and scope of the invention. Thus, if such modifications and variations of the present invention fall within the scope of the claims of the present invention and their equivalents, the present invention is also intended to include such modifications and variations.
Claims (2)
1. The utility model provides a blood amino acid and carnitine quantitative determination device based on electromagnetic control, includes blood robot (1), electromagnetic drive control module (2), blood information acquisition module (3) and blood information monitoring module (4), its characterized in that: the blood robot (1) is positioned in a venous blood vessel of a human body, the electromagnetic drive control module (2), the blood information acquisition module (3) and the blood information monitoring module (4) are arranged in a flat space, and the blood information acquisition module (3) and the blood information monitoring module (4) are connected through a digital signal wire;
the blood robot (1) comprises a motion control loop (1-1), a control loop connecting unit (1-2), a blood information emitter (1-3) and a blood information processor (1-4) which are sequentially connected, and also comprises an amino acid collector (1-5) and a carnitine collector (1-6) which are connected with the bottom end of the blood information processor (1-4);
the electromagnetic drive control module (2) comprises an electromagnetic drive controller support (2-1) with an inner ring, an electromagnetic drive controller (2-3) arranged on the inner ring of the electromagnetic drive controller support (2-1), a blood robot detector (2-2) arranged at the top end of the inner ring of the electromagnetic drive controller support (2-1), an electromagnetic drive control bed (2-4), an electromagnetic drive control bed lifting frame (2-5) and an electromagnetic drive control bed sliding base (2-6) which are sequentially connected;
the blood information acquisition module (3) comprises a blood information acquisition module support (3-5) provided with a mechanical interface, a blood robot signal receiver (3-1) arranged on the mechanical interface of the blood information acquisition module support (3-5), a blood robot signal processor (3-2) arranged on the mechanical interface of the blood information acquisition module support (3-5), an amino acid information display (3-3) arranged at the top end of the blood information acquisition module support (3-5), and a carnitine information display (3-4) arranged at the top end of the blood information acquisition module support (3-5);
the blood information monitoring module (4) comprises a blood information monitoring industrial personal computer (4-3) provided with a signal line interface, an amino acid real-time result display (4-1) arranged on the signal line interface of the blood information monitoring industrial personal computer (4-3), and a carnitine real-time result display (4-2) arranged on the signal line interface of the blood information monitoring industrial personal computer (4-3);
the blood robot (1) is driven in an electromagnetic driving mode;
the blood robot (1) is vertical, and the control ring connecting unit (1-2), the blood information emitter (1-3) and the blood information processor (1-4) are all columnar structures;
the structural form of the motion control ring (1-1) is a semicircular ring structure, and the number of the semicircular ring structures is 3:
the bottom materials of the amino acid collectors (1-5) and the carnitine collectors (1-6) are memory alloy materials;
the electromagnetic drive controller (2-3) is connected with the inner ring of the electromagnetic drive controller bracket (2-1) and is used for driving and controlling the motion process of the blood robot (1);
the electromagnetic drive control bed (2-4), the electromagnetic drive control bed lifting frame (2-5) and the electromagnetic drive control bed sliding base (2-6) are sequentially connected, so that the electromagnetic drive control bed (2-4) can move in the horizontal direction and the vertical direction.
2. The quantitative detection device for amino acids and carnitine in blood based on electromagnetic control of claim 1, wherein: the blood robot signal receiver (3-1), the blood robot signal processor (3-2) and the blood information monitoring industrial personal computer (4-3) adopt industrial computers.
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Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1686044A (en) * | 2005-04-29 | 2005-10-26 | 大连理工大学 | External magnetic field rotary driving control method of on line medical minitype robot in blood vessel |
| CN1973753A (en) * | 2006-12-21 | 2007-06-06 | 中国科学院电工研究所 | Micro robot and its in vitro guiding system |
| CN101594815A (en) * | 2006-11-22 | 2009-12-02 | 科连株式会社 | The endoscopy of capsule-type image photographing and the described equipment of use |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8246565B2 (en) * | 2009-02-25 | 2012-08-21 | The Invention Science Fund I, Llc | Device for passively removing a target component from blood or lymph of a vertebrate subject |
| US10598627B2 (en) * | 2012-06-29 | 2020-03-24 | Dexcom, Inc. | Devices, systems, and methods to compensate for effects of temperature on implantable sensors |
| US10945603B2 (en) * | 2017-03-20 | 2021-03-16 | At&T Intellectual Property I, L.P. | Detecting potential health risks using nanorobotics |
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Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1686044A (en) * | 2005-04-29 | 2005-10-26 | 大连理工大学 | External magnetic field rotary driving control method of on line medical minitype robot in blood vessel |
| CN101594815A (en) * | 2006-11-22 | 2009-12-02 | 科连株式会社 | The endoscopy of capsule-type image photographing and the described equipment of use |
| CN1973753A (en) * | 2006-12-21 | 2007-06-06 | 中国科学院电工研究所 | Micro robot and its in vitro guiding system |
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