CN111388879A - Radiation dose determination system, radiation dose determination device and storage medium - Google Patents
Radiation dose determination system, radiation dose determination device and storage medium Download PDFInfo
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Abstract
The invention discloses a radiation dose determination system, a radiation dose determination device and a storage medium. Wherein the system includes: comprising a memory for storing instructions and a processor configured to process the steps of: acquiring current radiotherapy data of a target object, wherein the radiotherapy data is used for determining corresponding dose distribution; acquiring pre-stored data of a target object, wherein the pre-stored data corresponds to historical radiotherapy data; and determining the dose distribution corresponding to the current radiotherapy data based on the current radiotherapy data of the target object and the pre-stored data. The radiotherapy data which is not changed is not required to be repeatedly acquired and processed, the processing step of the unchanged data is omitted, the calculation time of dose distribution is saved, the determination efficiency of the dose distribution is improved, and further, the efficiency of radiotherapy is improved.
Description
Technical Field
The embodiment of the invention relates to the technical field of medical equipment, in particular to a radiation dose determining system, a radiation dose determining device and a storage medium.
Background
Radiotherapy is a common treatment at present, and is the treatment of malignant tumors and some benign diseases by one or more ionizing radiations, wherein the determination of the dose distribution is an important step of radiotherapy.
With the continuous development of radiotherapy technologies, especially the development of four-dimensional radiotherapy technologies such as 4DCT (4D Computed Tomography), dose-guided intensity modulated radiotherapy (DGRT), etc., it is necessary to perform planning adjustment or setup adjustment again when the form and setup of a patient are inaccurate and the size and position of a tumor are changed, and accordingly, the dose calculation is required before each radiotherapy. However, even when a GPU (Graphics Processing Unit) is accelerated, the conventional dose distribution determining algorithm still requires several minutes to determine a precise dose distribution, which takes a long time.
Disclosure of Invention
The invention provides a radiation dose determination system, a radiation dose determination device and a storage medium, which are used for rapidly determining dose distribution.
In a first aspect, an embodiment of the present invention provides a radiation dose determination system, including:
a memory for storing instructions and a processor configured to process the steps of:
acquiring current radiotherapy data of a target object, wherein the radiotherapy data is used for determining corresponding dose distribution;
acquiring pre-stored data of a target object, wherein the pre-stored data corresponds to historical radiotherapy data;
and determining the dose distribution corresponding to the current radiotherapy data based on the current radiotherapy data of the target object and the pre-stored data.
In a second aspect, an embodiment of the present invention further provides a radiation dose determining apparatus, configured with a processor of a radiation dose determining system, including:
the system comprises a current radiotherapy data acquisition module, a target object detection module and a target object analysis module, wherein the current radiotherapy data acquisition module is used for acquiring current radiotherapy data of a target object, and the radiotherapy data is used for determining corresponding dose distribution;
the pre-stored data acquisition module is used for acquiring pre-stored data of the target object, and the pre-stored data corresponds to historical radiotherapy data;
and the dose distribution determining module is used for determining the dose distribution corresponding to the current radiotherapy data based on the current radiotherapy data of the target object and the pre-stored data.
In a third aspect, embodiments of the present invention also provide a storage medium containing computer-executable instructions which, when executed by a computer processor, perform a radiation dose determination method, the method comprising:
acquiring current radiotherapy data of a target object, wherein the radiotherapy data is used for determining corresponding dose distribution;
acquiring pre-stored data of a target object, wherein the pre-stored data corresponds to historical radiotherapy data;
and determining the dose distribution corresponding to the current radiotherapy data based on the current radiotherapy data of the target object and the pre-stored data.
According to the technical scheme provided by the embodiment of the invention, after the current radiotherapy data is acquired through the pre-stored data in the electronic device, the assistance of calculating the dose distribution of the current radiotherapy data is provided based on the unchanged data in the pre-stored data, the determination process of the unchanged data is reduced, the repeated acquisition and processing of the unchanged radiotherapy data are not needed, the processing step of the unchanged data is omitted, the calculation time of the dose distribution is saved, the determination efficiency of the dose distribution is improved, and further, the efficiency of radiotherapy is improved.
Drawings
FIG. 1 is a flow chart of radiation dose calculation in the prior art;
FIG. 2 is a schematic flow chart illustrating a method performed by a processor of a radiation dose determination system according to an embodiment of the present invention;
fig. 3 is a flowchart illustrating a method performed by a processor of a radiation dose determining system according to a second embodiment of the present invention;
fig. 4 is a flowchart illustrating a method performed by a processor of a radiation dose determining system according to a third embodiment of the present invention;
fig. 5 is a schematic structural diagram of a radiation dose determination apparatus according to a fourth embodiment of the present invention.
Detailed Description
The present invention will be described in further detail with reference to the accompanying drawings and examples. It is to be understood that the specific embodiments described herein are merely illustrative of the invention and are not limiting of the invention. It should be further noted that, for the convenience of description, only some of the structures related to the present invention are shown in the drawings, not all of the structures.
Referring to fig. 1, fig. 1 is a flow chart of radiation dose determination in the prior art. The dosage calculation method comprises the following steps: and step 10, carrying out reliability check on the data, specifically checking whether the CT image and the radiotherapy plan of the target object are stored. And 20, when the data is determined to be reliable, preprocessing the CT image to obtain an electron density image corresponding to the CT image. And step 30, reading preset data of radiotherapy equipment for executing radiotherapy, and establishing a source model based on the read preset data, wherein the preset data is Commission (modeling) data. And step 40, reading a radiotherapy plan of the target object, and determining a flux map based on the radiotherapy plan. And step 50, calculating and outputting the dose distribution of the target object required in the current radiotherapy based on the electron density image, the flux map, the source model and the nuclear/material database.
With respect to the characteristics of radiotherapy, the radiotherapy of the target object is not limited to one treatment, and the radiotherapy of the target object can be generally divided into 10 or 20 radiotherapy processes, and the above-mentioned dose calculation process is required for each radiotherapy process, wherein each step takes a certain amount of time, but in some cases, not each step needs to be performed again. In an application scenario of four-dimensional radiotherapy technologies such as DGRT, a radiotherapy plan does not need to be adjusted at each radiotherapy, that is, the radiotherapy plan is the same as a radiotherapy plan of a previous or first radiotherapy, or when the same radiotherapy device is applied, the Commission data of the radiotherapy device is the same, and Commission data do not need to be determined for the radiotherapy device one by one; or, since the target object is unchanged, and accordingly, the CT image of the target object is unchanged, a new CT image does not need to be acquired before each radiotherapy. The current dose calculation method has poor data reusability. In the present embodiment, improvement is made based on the above-described problem, and rapid determination of dose distribution is realized.
Example one
Fig. 2 is a schematic flowchart of a method executed by a processor in a radiation dose determination system according to an embodiment of the present invention, where the present embodiment is applicable to a case where radiation dose is calculated when radiotherapy is not first performed, and the method may be executed by the processor in the system according to the embodiment of the present invention, and specifically includes the following steps:
s110, obtaining current radiotherapy data of the target object, wherein the radiotherapy data is used for determining corresponding dose distribution.
And S120, acquiring pre-stored data of the target object, wherein the pre-stored data corresponds to historical radiotherapy data.
And S130, determining the dose distribution corresponding to the current radiotherapy data based on the current radiotherapy data of the target object and the pre-stored data.
In this embodiment, a database is established, where the database includes data storage files of each detection object, and the data storage files are used to store personal information of a target object and radiotherapy data applied in each dose distribution calculation, where after each dose distribution calculation, the radiotherapy data is stored in the database, it should be noted that the data storage file of the target object may include multiple sets of historical radiotherapy data, and the pre-stored data may be a set of historical radiotherapy data read from the data storage file of the target object for dose calculation.
The method includes acquiring identity information of a target object, wherein the identity information can be but is not limited to fingerprint information, face information, name information, identity document information or two-dimensional code information matched with the target object, and the like, querying a data storage file of the target object through the identity information, and reading pre-stored data of the target object from the data storage file.
When the pre-stored data of the target object is not included in the data storage file determined according to the identity information of the target object, the dose distribution of the current radiotherapy is determined based on the dose calculation process in fig. 1. When the corresponding pre-stored data is determined according to the identity information of the target object, the dose determination method in the present embodiment is performed. When the data storage file comprises more than two groups of historical radiotherapy data, the prestored data applied in the current dose calculation can be determined according to an externally input selection instruction, or the radiotherapy data of the previous radiotherapy can be determined as the prestored data applied in the current dose calculation. Optionally, the pre-stored data comprises at least one of an electron density image of the target object, a flux map of a radiation treatment plan, and a source model of radiation treatment.
Optionally, determining pre-stored data of the target object may further include: acquiring historical radiotherapy data of at least one group of target objects; and respectively determining the similarity between the current radiotherapy data and the at least one group of historical radiotherapy data, and determining prestored data applied in current dose calculation based on the group of historical radiotherapy data with the maximum similarity.
Wherein the current radiotherapy data of the target object may be data for calculating a current dose, and the current radiotherapy data may include at least one of a current image of the target object, a current radiotherapy plan, and preset parameters of a current radiotherapy apparatus. Wherein the current image may be a CT image of the target object. In some embodiments, the current radiotherapy data may also be data that changes relative to the historical radiotherapy data. The data quantity of the difference between the current radiotherapy data and the historical radiotherapy data is determined, the more the data quantity is, the lower the similarity is, and correspondingly, the less the data quantity is, the higher the similarity is. And determining the historical radiotherapy data with the maximum similarity as prestored data applied in the current dose distribution calculation, wherein the prestored data has small difference with the current data, and correspondingly, the data needing to be recalculated is small, so that the calculation amount in the current dose distribution determination process can be reduced, and the determination efficiency of the dose distribution is improved.
It should be noted that, if there is no difference data between the current radiotherapy data and the pre-stored data, the dose distribution in the historical radiotherapy data is used as the dose distribution of the current radiotherapy, and step S130 does not need to be executed.
Optionally, the determining a dose distribution corresponding to the current radiotherapy data based on the current radiotherapy data of the target object and the pre-stored data includes: determining difference data according to the current radiotherapy data and the historical radiotherapy data of the target object, wherein the difference data at least comprises at least one of image difference, radiotherapy plan difference and preset parameter difference of radiotherapy equipment; determining update data based on difference data, wherein the update data comprises at least one of an electron density image corresponding to the current image, a flux map corresponding to the current radiotherapy plan and a source model corresponding to preset parameters of current radiotherapy equipment, and determining dose distribution corresponding to the current radiotherapy data according to the update data and pre-stored data.
And comparing the acquired current radiotherapy data with historical radiotherapy data to determine difference data. The dose distribution corresponding to the current radiotherapy data is determined according to the difference data and the pre-stored data, wherein different difference data correspond to different dose distribution dose calculation modes, and in each dose calculation mode, only dose change caused by the difference data is calculated by means of the pre-stored data, and data which are not changed do not need to be re-determined, so that the determination efficiency of the dose distribution is improved.
Optionally, after the dose distribution of the current radiotherapy is determined, the current radiotherapy data and the dose distribution are stored in a data storage file of the target object.
Optionally, it is determined based on the current radiotherapy data of the target object and the pre-stored data that a dose distribution corresponding to the current radiotherapy data is calculated based on a preset mode. Illustratively, when dose calculation is started, the preset mode is triggered and started to execute the technical solution of the present embodiment, and illustratively, the preset mode may be triggered and started when a dose calculation page is entered or a current dose distribution is received. And under the preset mode, determining the dose distribution corresponding to the current radiotherapy data based on the current radiotherapy data of the target object and the pre-stored data. Further, in the preset mode, a dose calculation rule is determined based on the current radiotherapy data and pre-stored data, and the dose calculation rule is executed to quickly determine a dose distribution corresponding to the current radiotherapy data. For example, the electron density image is recalculated by default in the preset mode, and the corresponding dose distribution is rapidly calculated by using the recalculated electron density image and the flux map and the source model in the pre-stored data. In other embodiments, the preset mode may be a default re-calculated flux map or source model, and the dose distribution is calculated quickly by using the re-calculated flux map or source model and the pre-stored data. In other embodiments, two of the electron density image, the flux map, and the source model may also be recalculated in the default mode, and then the dose distribution is quickly calculated in conjunction with the pre-stored data.
Optionally, it is determined based on the current radiotherapy data of the target object and the pre-stored data that a dose distribution corresponding to the current radiotherapy data is calculated based on the received instruction. Wherein the method of the present embodiment is performed when the electronic device receives an instruction for controlling the dose calculation. The instruction may be input by pressing a specific key, voice, or the like. Similar to the preset pattern, the user can specify a recalculated module, using the recalculated data and pre-stored data to quickly calculate the dose distribution.
According to the technical scheme of the embodiment, after the current radiotherapy data is acquired through the pre-stored data in the electronic device, the assistance of calculating the dose distribution of the current radiotherapy data is provided based on the unchanged data in the pre-stored data, so that the determination process of the unchanged data is reduced, the repeated acquisition and processing of the unchanged radiotherapy data are not needed, the processing step of unchanged data is omitted, the calculation time of the dose distribution is saved, the determination efficiency of the dose distribution is improved, and further, the efficiency of radiotherapy is improved.
Example two
Fig. 3 is a schematic flowchart of a method executed by a processor in a radiation dose determination system according to a second embodiment of the present invention, which is detailed on the basis of the second embodiment, specifically:
s210, obtaining current radiotherapy data of the target object, wherein the radiotherapy data is used for determining corresponding dose distribution.
S220, pre-stored data of the target object are obtained, and the pre-stored data correspond to historical radiotherapy data.
And S230, registering according to the current image of the target object and the historical image corresponding to the electron density image in the pre-stored data, and determining a transformation matrix.
S240, determining an electron density image corresponding to the current image based on the electron density image in the pre-stored data and the transformation matrix.
And S250, determining the dose distribution corresponding to the current radiotherapy data based on the electron density image corresponding to the current image, the flux map of the radiotherapy plan in the prestored data and the source model of the radiotherapy.
Optionally, the difference data may be caused by a positioning difference of the target object, where the positioning difference of the target object is determined according to a positioning state of the target object in the current radiotherapy and a positioning state of the pre-stored data, where the positioning state of the target object may be acquired by a camera. It should be noted that the setup difference may be due to translation and/or rotation of the setup state of the target object in the current radiotherapy relative to the setup state of the history image corresponding to the electron density image.
In this embodiment, if only the positioning difference of the target object exists in the current radiotherapy process, the flux map of the radiotherapy plan of the target object and the source model of the radiotherapy and the like are not changed, it can be known that both the flux map of the radiotherapy plan and the source model of the radiotherapy in the pre-stored data belong to available data, and the electron density image is to-be-updated data. Accordingly, determining the update data based on the difference data may be: determining a transformation matrix according to the positioning difference, wherein the transformation matrix can be a translation matrix; and generating a new electron density image in the current radiotherapy according to the translation matrix and the electron density image in the pre-stored data. Specifically, the electron density image in the pre-stored data is multiplied by the translation matrix to obtain a new electron density image suitable for the current positioning of the target object. The positioning difference can be obtained by registering a current image based on the target object and a historical image corresponding to the electron density image in the pre-stored data, or by registering a positioning image acquired by a camera and a historical positioning image in the pre-stored data.
Correspondingly, dose calculation is carried out based on the electron density image corresponding to the current image, namely the new electron density image, the flux map of the radiation therapy plan which is not changed in the pre-stored data and the source model of the radiation therapy, the flux map of the radiation therapy plan which is not changed and the source model of the radiation therapy are directly adopted, the calculation process of the flux map and the creation process of the source model of the radiation therapy are omitted, and the electron density image in the pre-stored data is subjected to translation processing only according to the transformation matrix, so that the operation is simple, the speed is high, the calculation process of the electron density image is simplified, and the dose calculation efficiency is improved.
According to the technical scheme of the embodiment, when the positioning state of the target object changes relative to the positioning state in the pre-stored data, the current image of the target object and the historical image corresponding to the electron density image in the pre-stored data are registered to obtain a transformation matrix, the electron density image in the pre-stored data is processed based on the transformation matrix to obtain a new electron density image, and the dose distribution corresponding to the current radiotherapy data is obtained based on the new electron density image. And a new electron density image is obtained through simple image transformation, so that the calculation process of the electron density image is simplified, and the calculation of the dose distribution is further accelerated.
EXAMPLE III
Fig. 4 is a schematic flowchart of a method executed by a processor in a radiation dose determination system according to a third embodiment of the present invention, which is detailed on the basis of the third embodiment, specifically:
s310, obtaining current radiotherapy data of the target object, wherein the radiotherapy data is used for determining corresponding dose distribution.
S320, pre-stored data of the target object are obtained, and the pre-stored data correspond to historical radiotherapy data.
And S330, determining the variable quantity and invariant of the current radiotherapy plan relative to the historical radiotherapy plan.
And S340, determining a dose distribution corresponding to the variation based on the variation and the pre-stored data.
And S350, determining the dose distribution corresponding to the current radiotherapy data based on the dose distribution corresponding to the variable and the dose distribution corresponding to the invariant.
In this embodiment, the radiation therapy plan includes a radiation sub-field, and accordingly, the variation amount of the current radiation therapy plan from the historical radiation therapy plan may be a variation of the sub-field, such as a variation, an addition, or a deletion of the sub-field. Optionally, the pre-stored data may include dose distributions corresponding to respective sub-fields in the historical radiotherapy plan. In this embodiment, if there is only a change of a part of the sub-fields in the current radiation treatment plan, in the process of dose calculation, the dose distribution of only the changed sub-fields is changed without affecting the dose distribution of the non-changed sub-fields, and by recalculating the dose distribution of the changed sub-fields, the dose distribution corresponding to the current radiation treatment plan is obtained based on the recalculated dose distribution of the changed sub-fields and the dose distribution of the non-changed sub-fields. The dose distribution of any sub-field is calculated based on the electron density image in the pre-stored data, the flux map of the sub-field and the radiation therapy source model, and the method is the same as the method for calculating the dose distribution in fig. 1 or any embodiment of the present application, and is not repeated here.
Optionally, when the variation of the current radiotherapy plan relative to the historical radiotherapy plan is changed subfield data, the dose distribution corresponding to the variation is replaced with the dose distribution corresponding to the historical radiotherapy plan in the dose distribution of the pre-stored data, so as to obtain the dose distribution corresponding to the current radiotherapy data. Illustratively, when the radiotherapy plan in the pre-stored data includes 180 sub-fields, wherein if the variation of the current radiotherapy plan is 180 sub-fields and 1-179 sub-fields are invariant, only the dose distribution of the 180 sub-fields is calculated, and the dose distribution corresponding to the current radiotherapy data is determined based on the calculated dose distribution of the 180 sub-fields and the dose distribution of the 1-179 sub-fields in the pre-stored data.
Optionally, when the amount of change of the current radiotherapy plan relative to the historical radiotherapy plan is new-added sub-field data, determining the dose distribution of the current radiotherapy based on the dose distribution of the new-added sub-field data and the dose distribution of each sub-field in the historical radiotherapy plan of the pre-stored data. Illustratively, when the historical radiotherapy plan in the pre-stored data includes 90 segments, wherein if the variation of the current radiotherapy plan is that 10 new segments are added and the added segments do not overlap with the 90 segments in the pre-stored data, only the dose distribution of the newly added segment data is calculated, and the dose distribution of the current radiotherapy is determined based on the sum of the calculated dose distribution of the newly added segment data and the dose distribution of each segment in the historical radiotherapy plan of the pre-stored data.
According to the technical scheme of the embodiment, when the current radiotherapy plan has partial variables relative to the historical radiotherapy plan, only the dose distribution corresponding to the variables in the current radiotherapy plan is calculated, and the dose distribution corresponding to the current radiotherapy data is obtained based on the dose distribution corresponding to the variables and the dose distribution of the invariants in the pre-stored data.
On the basis of the above embodiment, determining a dose distribution corresponding to current radiotherapy data based on the current radiotherapy data of the target object and the pre-stored data includes: determining a corresponding flux map according to the current radiotherapy plan of the target object; and determining the dose distribution corresponding to the current radiotherapy data based on the flux map corresponding to the current radiotherapy plan, the electron density image in the pre-stored data and the source model of radiotherapy.
The variable quantity of the current radiotherapy plan relative to the historical radiotherapy plan in the pre-stored data is a variable parameter, and the variable parameter is determined according to an externally input modification instruction; wherein the variable parameter may be a modified parameter in the radiotherapy plan, such as but not limited to a modified radiation angle, position, etc. In this embodiment, if only the radiotherapy plan is modified in the current radiotherapy data, the electron density image of the target object and the source model of radiotherapy and the like are not changed, and the flux map is the data to be updated.
And determining a corresponding new flux map according to the current radiotherapy plan of the target object. Correspondingly, the dose distribution corresponding to the current radiotherapy data is determined based on the new flux map, the unchanged electron density image in the pre-stored data and the radiotherapy source model, the electron density image in the pre-stored data and the radiotherapy source model are directly called, the calculation time is saved, and the calculation of the dose distribution is accelerated.
On the basis of the above embodiment, determining a dose distribution corresponding to current radiotherapy data based on the current radiotherapy data of the target object and the pre-stored data includes: determining a corresponding source model according to preset parameters of the current radiotherapy equipment of the target object; and determining the dose distribution corresponding to the current radiotherapy data based on the source model corresponding to the preset parameters of the current radiotherapy equipment, the electron density image in the pre-stored data and the flux map of the radiotherapy plan.
When the preset parameters of the current radiotherapy equipment are changed, the electron density image in the pre-stored data and the flux map of the radiotherapy plan are unchanged, the electron density image in the pre-stored data and the flux map of the radiotherapy plan are directly called, and the dose distribution corresponding to the current radiotherapy data is determined based on a new source model determined by the preset parameters of the current radiotherapy equipment in the current radiotherapy data. The calculation process of the electron density image and the flux map of the radiotherapy plan is omitted, the calculation time is omitted, and the calculation of the dose distribution is accelerated.
Example four
Fig. 5 is a radiation dose determining apparatus according to a fourth embodiment of the present invention, configured in a processor of a radiation dose determining system, including:
a current radiotherapy data acquisition module 410, configured to acquire current radiotherapy data of a target object, where the radiotherapy data is used to determine a corresponding dose distribution;
a pre-stored data obtaining module 420, configured to obtain pre-stored data of a target object, where the pre-stored data corresponds to historical radiotherapy data;
a dose distribution determining module 430, configured to determine a dose distribution corresponding to the current radiotherapy data based on the current radiotherapy data of the target object and the pre-stored data.
Optionally, the current radiotherapy data includes at least one of a current image of the target object, a current radiotherapy plan, and preset parameters of a current radiotherapy device;
the pre-stored data includes at least one of an electron density image of the target object, a flux map of a radiation treatment plan, and a source model of radiation treatment.
Optionally, the pre-stored data obtaining module 420 is configured to:
acquiring historical radiotherapy data of at least one group of target objects;
determining similarity of the current radiotherapy data and the at least one set of historical radiotherapy data respectively,
pre-stored data applied in the current dose calculation is determined based on a set of historical radiotherapy data with the greatest similarity.
Optionally, the dose distribution determining module 430 includes:
a difference data determining unit, configured to determine difference data according to current radiotherapy data of the target object and the historical radiotherapy data, where the difference data at least includes at least one of an image difference, a radiotherapy plan difference, and a preset parameter difference of radiotherapy equipment;
an update data determination unit for determining update data based on the difference data, the update data including at least one of an electron density image corresponding to the current image, a flux map corresponding to the current radiotherapy plan, and a source model corresponding to preset parameters of the current radiotherapy apparatus,
and the first dose distribution calculating unit is used for determining the dose distribution corresponding to the current radiotherapy data according to the updated data and the prestored data.
Optionally, the dose distribution determining module 430 includes:
a variation determining unit for determining variation and invariance of the current radiotherapy plan relative to the historical radiotherapy plan;
a second dose distribution determining unit, configured to determine a dose distribution corresponding to the variation based on the variation and the pre-stored data;
and the third dose distribution determining unit is used for determining the dose distribution corresponding to the current radiotherapy data based on the dose distribution corresponding to the variable and the dose distribution corresponding to the invariant.
Optionally, the dose distribution determining module 430 includes:
a transformation matrix determining unit, configured to perform registration according to the current image of the target object and a history image corresponding to the electron density image in the pre-stored data, and determine a transformation matrix;
an electron density image determining unit, configured to determine an electron density image corresponding to the current image based on the electron density image in the pre-stored data and the transformation matrix;
and the fourth dose distribution determining unit is used for determining the dose distribution corresponding to the current radiotherapy data based on the electron density image corresponding to the current image, the flux map of the radiotherapy plan in the prestored data and the source model of the radiotherapy.
Optionally, the dose distribution determining module 430 includes:
the flux map determining unit is used for determining a corresponding flux map according to the current radiotherapy plan of the target object;
and the fifth dose distribution determining unit is used for determining the dose distribution corresponding to the current radiotherapy data based on the flux map corresponding to the current radiotherapy plan, the electron density image in the prestored data and the source model of radiotherapy.
Accordingly, the dose distribution determination module 430 includes:
the source model determining unit is used for determining a corresponding source model according to preset parameters of the current radiotherapy equipment of the target object;
and the sixth dose distribution determining unit is used for determining the dose distribution corresponding to the current radiotherapy data based on the source model corresponding to the preset parameters of the current radiotherapy equipment, the electron density image in the pre-stored data and the flux map of the radiotherapy plan.
Optionally, the dose distribution corresponding to the current radiotherapy data determined based on the current radiotherapy data of the target object and the pre-stored data is calculated based on a preset mode.
Optionally, the determining of the dose distribution corresponding to the current radiotherapy data based on the current radiotherapy data of the target object and the pre-stored data is performed based on a received instruction.
EXAMPLE five
A fourth embodiment of the invention also provides a storage medium containing computer-executable instructions which, when executed by a computer processor, perform a radiation dose determination method comprising:
acquiring current radiotherapy data of a target object, wherein the radiotherapy data is used for determining corresponding dose distribution;
acquiring pre-stored data of a target object, wherein the pre-stored data corresponds to historical radiotherapy data;
and determining the dose distribution corresponding to the current radiotherapy data based on the current radiotherapy data of the target object and the pre-stored data.
Of course, the embodiments of the present invention provide a storage medium containing computer-executable instructions, which are not limited to the method operations described above, but can also perform operations related to the steps performed by the processor in the radiation therapy planning system provided by any embodiments of the present invention.
Based on the understanding that the technical solutions of the present invention can be embodied in the form of software products, which can be stored in a computer-readable storage medium, such as a floppy disk, a Read-Only Memory (ROM), a Random Access Memory (RAM), a flash Memory (F L ASH), a hard disk or an optical disk of a computer, and the like, and include instructions for enabling a computer device (which may be a personal computer, a server, or a network device, and the like) to execute the methods and steps described in the embodiments of the present invention.
It should be noted that, in the embodiment of the radiation treatment plan optimization apparatus, the units, sub-units, and modules included in the embodiment are only divided according to the functional logic, but are not limited to the above division as long as the corresponding functions can be implemented; in addition, specific names of the functional units are only for convenience of distinguishing from each other, and are not used for limiting the protection scope of the present invention.
It is to be noted that the foregoing is only illustrative of the preferred embodiments of the present invention and the technical principles employed. It will be understood by those skilled in the art that the present invention is not limited to the particular embodiments described herein, but is capable of various obvious changes, rearrangements and substitutions as will now become apparent to those skilled in the art without departing from the scope of the invention. Therefore, although the present invention has been described in greater detail by the above embodiments, the present invention is not limited to the above embodiments, and may include other equivalent embodiments without departing from the spirit of the present invention, and the scope of the present invention is determined by the scope of the appended claims.
Claims (12)
1. A radiation dose determination system comprising a memory for storing instructions and a processor configured to process the steps of:
acquiring current radiotherapy data of a target object, wherein the radiotherapy data is used for determining corresponding dose distribution;
acquiring pre-stored data of a target object, wherein the pre-stored data corresponds to historical radiotherapy data;
and determining the dose distribution corresponding to the current radiotherapy data based on the current radiotherapy data of the target object and the pre-stored data.
2. A radiation dose determination system as defined in claim 1,
the current radiotherapy data comprises at least one of a current image of the target object, a current radiotherapy plan and preset parameters of a current radiotherapy device;
the pre-stored data includes at least one of an electron density image of the target object, a flux map of a radiation treatment plan, and a source model of radiation treatment.
3. A radiation dose determination system as claimed in claim 1, wherein said acquiring pre-stored data of a target object comprises:
acquiring historical radiotherapy data of at least one group of target objects;
determining similarity of the current radiotherapy data and the at least one set of historical radiotherapy data respectively,
pre-stored data applied in the current dose calculation is determined based on a set of historical radiotherapy data with the greatest similarity.
4. A radiation dose determination system as claimed in claim 2 wherein determining a dose distribution corresponding to current radiotherapy data based on the current radiotherapy data of the target object and the pre-stored data comprises:
determining difference data according to the current radiotherapy data and the historical radiotherapy data of the target object, wherein the difference data at least comprises at least one of image difference, radiotherapy plan difference and preset parameter difference of radiotherapy equipment;
determining update data based on the difference data, wherein the update data comprises at least one of an electron density image corresponding to the current image, a flux map corresponding to the current radiotherapy plan, and a source model corresponding to preset parameters of the current radiotherapy equipment,
and determining the dose distribution corresponding to the current radiotherapy data according to the updated data and the pre-stored data.
5. A radiation dose determination system as claimed in claim 2 wherein determining a dose distribution corresponding to current radiotherapy data based on the current radiotherapy data of the target object and the pre-stored data comprises:
determining variations and invariants of a current radiation therapy plan relative to the historical radiation therapy plans;
determining a dose distribution corresponding to the variation based on the variation and the pre-stored data;
and determining the dose distribution corresponding to the current radiotherapy data based on the dose distribution corresponding to the variable and the dose distribution corresponding to the invariant.
6. A radiation dose determination system as claimed in claim 2 or 4, wherein determining a dose distribution corresponding to current radiotherapy data based on the current radiotherapy data of the target object and the pre-stored data comprises:
registering according to the current image of the target object and a historical image corresponding to the electron density image in the pre-stored data, and determining a transformation matrix;
determining an electron density image corresponding to the current image based on the electron density image in the pre-stored data and the transformation matrix;
and determining the dose distribution corresponding to the current radiotherapy data based on the electron density image corresponding to the current image, the flux map of the radiotherapy plan in the prestored data and the source model of the radiotherapy.
7. A radiation dose determination system as claimed in claim 2 or 4, wherein determining a dose distribution corresponding to current radiotherapy data based on the current radiotherapy data of the target object and the pre-stored data comprises:
determining a corresponding flux map according to the current radiotherapy plan of the target object;
and determining the dose distribution corresponding to the current radiotherapy data based on the flux map corresponding to the current radiotherapy plan, the electron density image in the pre-stored data and the source model of radiotherapy.
8. A radiation dose determination system as claimed in claim 2 or 4, wherein determining a dose distribution corresponding to current radiotherapy data based on the current radiotherapy data of the target object and the pre-stored data comprises:
determining a corresponding source model according to preset parameters of the current radiotherapy equipment of the target object;
and determining the dose distribution corresponding to the current radiotherapy data based on the source model corresponding to the preset parameters of the current radiotherapy equipment, the electron density image in the pre-stored data and the flux map of the radiotherapy plan.
9. A radiation dose determination system as claimed in claim 1, wherein the determination of the dose distribution corresponding to the current radiotherapy data based on the current radiotherapy data of the target object and the pre-stored data is calculated based on a preset pattern.
10. A radiation dose determination system as claimed in claim 1 wherein the determination of the dose distribution corresponding to current radiotherapy data based on current radiotherapy data of the target object and the pre-stored data is calculated based on the received instructions.
11. A radiation dose determining apparatus configured to operate with a processor of a dose distribution determining system, comprising:
the system comprises a current radiotherapy data acquisition module, a target object detection module and a target object analysis module, wherein the current radiotherapy data acquisition module is used for acquiring current radiotherapy data of a target object, and the radiotherapy data is used for determining corresponding dose distribution;
the pre-stored data acquisition module is used for acquiring pre-stored data of the target object, and the pre-stored data corresponds to historical radiotherapy data;
and the dose distribution determining module is used for determining the dose distribution corresponding to the current radiotherapy data based on the current radiotherapy data of the target object and the pre-stored data.
12. A storage medium containing computer-executable instructions, which when executed by a computer processor, perform a radiation dose determination method, comprising:
acquiring current radiotherapy data of a target object, wherein the radiotherapy data is used for determining corresponding dose distribution;
acquiring pre-stored data of a target object, wherein the pre-stored data corresponds to historical radiotherapy data;
and determining the dose distribution corresponding to the current radiotherapy data based on the current radiotherapy data of the target object and the pre-stored data.
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