CN110988102B - Visual sheath-flow-free single-cell mass spectrometry system - Google Patents
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- CN110988102B CN110988102B CN201911265412.7A CN201911265412A CN110988102B CN 110988102 B CN110988102 B CN 110988102B CN 201911265412 A CN201911265412 A CN 201911265412A CN 110988102 B CN110988102 B CN 110988102B
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/62—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating the ionisation of gases, e.g. aerosols; by investigating electric discharges, e.g. emission of cathode
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N2015/1006—Investigating individual particles for cytology
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CN201911265412.7A CN110988102B (en) | 2019-12-10 | 2019-12-10 | Visual sheath-flow-free single-cell mass spectrometry system |
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CN111397985B (en) * | 2020-04-14 | 2021-01-08 | 清华大学 | Single cell mass spectrometry |
CN111982789B (en) * | 2020-08-21 | 2022-02-08 | 中国科学院生态环境研究中心 | High-throughput detection method of metal ions and metal nanoparticles based on single-cell enrichment and single-cell mass spectrometry |
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GB0524979D0 (en) * | 2005-12-07 | 2006-01-18 | Queen Mary & Westfield College | An electrospray device and a method of electrospraying |
WO2010127059A1 (en) * | 2009-04-30 | 2010-11-04 | Purdue Research Foundation | Ion generation using wetted porous material |
JP5359924B2 (en) * | 2010-02-18 | 2013-12-04 | 株式会社島津製作所 | Mass spectrometer |
JP2016075574A (en) * | 2014-10-06 | 2016-05-12 | キヤノン株式会社 | Mass microscope device |
JP6498497B2 (en) * | 2015-04-01 | 2019-04-10 | 学校法人慶應義塾 | Method of creating spray device for sheathless CE-MS, spray device for sheathless CE-MS, and sheathless CE-MS device |
CN105575752B (en) * | 2016-03-04 | 2017-09-22 | 北京工业大学 | A kind of difunctional uniform internal diameter skin liquid spectrum nozzle needle and preparation method |
CN106384705B (en) * | 2016-08-29 | 2019-02-19 | 山东省分析测试中心 | A kind of high-throughput Nanoliter electrospray analysis system and its application based on miniature array |
AU2017319400A1 (en) * | 2016-08-31 | 2019-03-21 | Avectas Limited | Adaptive electrospray device |
CN109357991B (en) * | 2018-09-27 | 2020-05-26 | 清华大学 | Mass spectrum flow cytometry sample introduction and ionization device based on marking-free principle |
CN109557163B (en) * | 2018-11-27 | 2023-09-15 | 清华大学 | Living single-cell in-situ extraction and online mass spectrum detection device and application |
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Inventor after: Guo Guangsheng Inventor after: Zhu Guizhen Inventor after: Shao Yunlong Inventor after: Liu Yingying Inventor after: Liu Yuanxing Inventor after: Yan Yong Inventor after: Liu Zhihong Inventor after: Wang Xiayan Inventor before: Guo Guangsheng Inventor before: Zhu Guizhen Inventor before: Shao Yunlong Inventor before: Liu Yingying Inventor before: Liu Yuanxing Inventor before: Yan Yong Inventor before: Wang Xiayan |
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