CN110732087A - Portable treatment auxiliary system - Google Patents

Portable treatment auxiliary system Download PDF

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Publication number
CN110732087A
CN110732087A CN201810804515.5A CN201810804515A CN110732087A CN 110732087 A CN110732087 A CN 110732087A CN 201810804515 A CN201810804515 A CN 201810804515A CN 110732087 A CN110732087 A CN 110732087A
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patient
data
assistance system
portable
electrode
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CN201810804515.5A
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Chinese (zh)
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卢健
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Hunan Antai Kangcheng Biotechnology Co Ltd
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Hunan Antai Kangcheng Biotechnology Co Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N2/00Magnetotherapy
    • A61N2/002Magnetotherapy in combination with another treatment
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N2/00Magnetotherapy
    • A61N2/004Magnetotherapy specially adapted for a specific therapy

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)

Abstract

The invention provides a portable therapy assistance system, which includes an electrode adapted to be operatively attached to a patient and adapted to provide an electric and/or magnetic field to a target area within the patient, a three-dimensional positioning device adapted to provide a protocol of placement locations and quantities of the electrode based on DICOM data of the patient, and a wearable assistance component adapted to assist in the attachment of the electrode to the patient according to the protocol.

Description

Portable treatment auxiliary system
Technical Field
The present invention relates to systems for use in the medical and/or healthcare field, and more particularly to portable therapy assistance systems.
Background
The basic principle of the current electric Field (TTF) for tumor therapy is based on the mitotic hindrance of the electric Field to the tumor cells. Different frequencies, different directions and different intensities of the electric field all show different tumor inhibition effects.
The TTF-100A electric field treatment equipment manufactured by Yoram Palti company, a person beginning in tumor treatment electric field, is the most commonly used equipment for patients with glioma in the prior treatment, adopts a front-back and left-right 2 pairs of electrode plate arrays to cling to the scalp of the patient, and lacks an electrode position scheme specific to a tumor part.
The magnetic field and the electric field have interdependent relation, research shows that the proper magnetic field and electric field have positive biological significance, the local or/and whole body application of pulse electromagnetic field has definite improvement effect on brain function, tumor, Parkinson's disease, osteoarthritis, postoperative pain, etc., wherein transcranial magnetic stimulation utilizes the magnetic field to excite induced current of cerebral cortex, has better nerve excitation regulation function, can be clinically applied to the treatment of depression, in addition, the magnetic field can inhibit or kill tumor cells based on the local heating effect or the promotion of cancer-inhibiting molecular pathway to the tumor, however, the lack of precise positioning means is which restricts the clinical curative effect of the magnetic field.
Disclosure of Invention
In view of the problems with the prior art treatment devices, it is an object of the present invention to provide portable treatment support systems that can determine position and provide an accurate treatment plan.
The invention provides a portable therapy assistance system comprising an electrode adapted to be operatively attached to a patient and adapted to provide an electric and/or magnetic field to a target area within the patient, a three-dimensional positioning device adapted to provide a protocol of placement locations and numbers of electrodes based on DICOM data of the patient, and a wear assistance component adapted to assist in the attachment of the electrode to the patient based on the protocol.
, the three-dimensional positioning device includes an anatomical structure imaging image processing module, a multi-modality image processing module, a multi-physical field simulation model module and an optimization solving module, wherein the anatomical structure imaging image processing module is configured to receive DICOM data of a patient and perform image segmentation on the DICOM data to obtain segmented data, the multi-modality image processing module is configured to import the segmented data and convert the segmented data into mesh reconstruction data through a mesh division algorithm to form three-dimensional mesh reconstruction modeling data of a target region/target region in the patient, the multi-physical field simulation model module is configured to establish an electric field and/or magnetic field strength optimization solving model according to electric field and/or magnetic field strength requirements required by the target region in the patient, and the optimization module is configured to import the received three-dimensional mesh reconstruction modeling data formed by the multi-modality image processing module into the electric field and/or magnetic field strength optimization solving model to solve to obtain a scheme of the placement positions and the number of the electrodes.
In embodiments, the optimization solver module is configured to solve for at least of the solutions.
In some embodiments, the portable system further comprises a 3D printout module, the 3D printout module is suitable for printing the wearable auxiliary component according to the scheme of the placement position and the number of the electrodes, the printed wearable auxiliary component comprises at least marks for indicating the placement position of the electrodes, the electrodes are mounted on the wearable auxiliary component according to the marks so as to be indirectly attached to the patient, or the electrodes are attached to the body surface of the patient according to the marks of the wearable auxiliary component so as to be directly attached to the patient.
In , the wear assist feature includes a -th wear for the patient's head and/or a second wear for the patient's torso the -th wear is hat-shaped or pillow-shaped and the second wear is a chest waist and abdomen patch, chest waist and abdomen band, or shorts.
In embodiments, the wearable accessory is configured to be formed of a flexible material or a hard material selected from or more of plastic, rubber, silicone, resin, nylon, and metal materials.
Compared with the prior art, the invention has the following beneficial technical effects:
the treatment auxiliary system can obtain different schemes according to different patient conditions, accurately simulate the position and the number of the positioning electrodes, and provide the wearing auxiliary component to assist the placement of the electrodes.
In addition, the placement position of the electrode can be accurately determined by arranging the installation mark on the wearing part, so that the electrode can be conveniently placed and an electric field or a magnetic field can be subsequently applied.
Drawings
FIG. 1 is a schematic diagram of a portable therapy assistance system according to embodiments of the present invention.
Fig. 2 is an enlarged schematic view of the wearing aid member in fig. 1.
Fig. 3 is a block diagram of an assistance method of the portable assistance system in fig. 1.
Detailed Description
Various aspects of the invention are described in detail below with reference to the following figures and detailed description, wherein the components in the figures are not necessarily to scale and wherein emphasis is placed upon illustrating the principles of the invention.
In addition, those skilled in the art will appreciate that the various embodiments described below are illustrative only and not intended to limit the scope of the invention.
FIG. 1 is a schematic diagram of a portable therapy assistance system according to embodiments of the present invention, as shown in FIG. 1, the portable therapy system of the present embodiment may include, but is not limited to, an electrode 1, a three-dimensional positioning device 2, and a wearable assistance component 3, wherein the electrode 1 is adapted to be operatively attached to a patient and adapted to provide an electric and/or magnetic field to a target area within the patient's body, the three-dimensional positioning device 2 is adapted to provide a scheme of placement locations and numbers of electrodes based on DICOM data of the patient, and the wearable assistance component 3 is adapted to assist in attaching the electrode 1 to the patient based on the scheme provided by the three-dimensional positioning device 2.
In other words, the three-dimensional positioning device is used for assisting in determining the placement scheme of the electrode, and the wearing assisting component is used for assisting in the placement of the electrode, so that the patient can place the electrode in a proper position according to an expected treatment scheme before beginning formal treatment, and subsequent treatment is facilitated.
For example, the wearable auxiliary member may be an -time temporary auxiliary member, which is removed after the auxiliary electrode is placed in cases of treatment, or a long-term auxiliary member, which remains still after the auxiliary electrode is placed in each treatment to fix the position of the electrode.
The three-dimensional positioning device 2 may rely on hardware (e.g., a computer, etc.), including, but not limited to, an anatomical imaging image processing module, a multi-modal image processing module, a multi-physical field simulation model module, an optimization solving module, and the like, and the three-dimensional positioning device 2 includes a data receiving/transmitting device, a data storage device, a display, a processor, and the like, wherein the data receiving/transmitting device is adapted to receive and transmit data, the data storage device is adapted to store data, the display is adapted to display a scheme of placement positions and numbers of electrodes, and the like, and the processor executes computer instructions to perform operations corresponding to these modules.
The anatomical imaging image processing module is configured to receive DICOM data from a patient and perform image segmentation on the DICOM data to obtain segmentation data. For example, the DICOM data may be obtained by scanning a patient body with an external device such as CT, MRI, or PET, and may include image scanning raw data of the patient such as CT, MRI, or PET. For example, for a head tumor, the patient's DICOM data may be MRI raw DICOM data about the patient's head obtained by MRI scanning the head; when the target region such as the thoraco-abdominal region and the pelvic region is targeted, the DICOM data of the patient may be the raw DICOM data on the abdomen of the patient obtained by CT scanning of the abdomen, or the like. The anatomical imaging image processing module may be image segmentation software by which image segmentation is performed on the obtained DICOM data (image data).
The multi-modality image processing module is configured to import the segmentation data and convert the segmentation data into mesh reconstruction data by a mesh segmentation algorithm, thereby forming three-dimensional mesh reconstruction modeling data 21 (shown in fig. 1) of the lesion tissue in the patient. The three-dimensional gridded reconstructed modeling data 21 herein may also be displayed on a display for viewing by a user.
The multi-physical-field simulation model module is configured to establish an electric field and/or magnetic field strength optimization solution model according to electric field and/or magnetic field strength requirements of a target region in a patient. The electric and/or magnetic field strength requirements for a target region in a patient's body may be input into the three-dimensional positioning apparatus 2 by a data receiving and transmitting device, or may be displayed on a display for viewing by a user. The established electric field and/or magnetic field intensity optimization solution model can also be displayed on a display.
The optimization solution module is arranged to introduce the three-dimensional gridding reconstruction modeling data 21 into an electric field and/or magnetic field strength optimization solution model, and to solve for a solution 22 regarding the placement positions and number of electrodes. The protocol 22 may include voltage magnitude parameters for each electrode in addition to the number of electrode placements, location distribution, etc. The solution 22 may be displayed on a display for viewing and selection by a user.
In , the optimization solution module may solve for at least two solutions, each solution having a different electrode placement location.
For example, the constraint condition may be set to be that the position of each electrode of each scheme is different, or more schemes (including parameters such as the number of electrodes, the position, the voltage amplitude of each electrode, etc.) are generated by an iterative optimization method, and the different electrode schemes may achieve the same electric field and/or magnetic field intensity effect.
As shown in FIG. 1, in the present invention, the portable auxiliary system may further include a 3D printout module 4, the 3D printout module is adapted to be printed to form a wearable auxiliary component according to the scheme 22, the 3D printout module may be a 3D printer or other forms, the wearable auxiliary component may be formed by 3D printing using a flexible material or a hard material, for example, the flexible material or the hard material may be selected from or more materials such as plastic, rubber, silicon gel, resin, nylon, and metal.
For example, the garment may be hat-shaped or pillow-shaped (for head tumors), and the second garment may be a chest waist and abdomen patch, a chest waist and abdomen circumference, or shorts-shaped (for target area or fast-growing diseased tissue of the corresponding site).
FIG. 2 is an enlarged view of the auxiliary wearing part 3 of FIG. 1. As shown in FIG. 2, the auxiliary wearing part may be a hat for the tumor of the head of the patient, the hat may be 3D printed and has at least marks 31 for indicating the installation positions of the electrodes, when in use, the electrodes may be installed or arranged at corresponding positions on the hat by the user according to the marks on the hat, so as to be indirectly attached to the patient or directly attached to the body surface of the patient.
In an alternative embodiment, the electrode may also be directly attached to the body surface of the patient according to the mark indication of the wearing auxiliary component, for example, the mark on the wearing auxiliary component may be a hollow mark, and the electrode is directly attached to the body surface of the patient.
Fig. 3 shows a block diagram of the assistance method of the portable assistance system of the invention. As shown in fig. 3, during the use of the system, the auxiliary system of the present invention may operate as follows:
in step 101, a patient body is scanned and DICOM data is obtained. For example, the patient body may be scanned by an external device such as CT, MRI, PET, etc., and the obtained DICOM data may include raw data of image scanning such as CT, MRI, PET, etc. of the patient. For example, for a head tumor, the head may be scanned by MRI to obtain MRI raw DICOM data about the patient's head.
In step 102, the anatomical imaging image processing module of the auxiliary system receives the DICOM data of the patient in step 101, and performs image segmentation on the DICOM data to obtain segmented data. Image segmentation may be performed by image segmentation software.
In step 103, the segmentation data from step 102 is imported into a multi-modality image processing module and converted into mesh reconstruction data by a meshing algorithm, thereby forming three-dimensional meshed reconstruction modeling data of the lesion tissue in the patient (as shown by the three-dimensional meshed reconstruction modeling data 21 in fig. 1).
In step 104, an electric field and/or magnetic field strength optimization solution model is established through a multi-physical field simulation model module according to the electric field and/or magnetic field strength requirements of the diseased tissue in the body of the patient.
In step 105, the received three-dimensional gridded reconstruction modeling data is imported into the electric field and/or magnetic field strength optimization solution model, and a solution (shown as solution 22 in fig. 1) for obtaining the positions and the number of the electrode placements is solved. Specifically, a target position (for example, a tumor or a disease region) is outlined in a three-dimensional space of the three-dimensional gridding reconstruction modeling data 21, treatment target parameters such as the strength of an electric field and/or a magnetic field at a specified distance inside and outside the boundary of the target region are set, and an inverse solution algorithm is invoked to obtain a combined scheme (i.e., a determined scheme 22) regarding the number of electrode placements, the position distribution, and the voltage amplitudes of the electrodes.
In embodiments, in this step, the optimization solution module may solve to obtain at least two solutions, where the electrode placement positions in each solution are different, for example, constraint conditions may be set to be different for each solution, and one or more solutions (including parameters such as the number of electrodes, the position of each electrode, and the voltage amplitude of each electrode) may be generated by an iterative optimization method, and the different electrode solutions may achieve the same electric field and/or magnetic field strength effect.
In step 106, the scheme is imported into a 3D printout module, and the corresponding wearing auxiliary component is printed out.
In step 107, the electrodes are mounted to the wearable aid to be indirectly attached to the patient or directly attached to the body surface of the patient based on the printed wearable aid the wearable aid can then be torn off or left on the body surface of the patient to fix the electrode position.
By using the auxiliary system provided by the invention, a user can accurately determine the distribution position and number scheme of the electrodes, can print out a proper wearable auxiliary component according to the body type and the like of an actual patient, and can install the electrodes to the proper position of the wearable auxiliary component or directly to the body surface of the patient according to the determined scheme, so that effective treatment can be conveniently carried out subsequently.
Although exemplary embodiments have been described herein by way of example, various modifications may be made to these embodiments without departing from the spirit of the invention, and all such modifications are intended to be included within the scope of the invention as defined in the following claims.
The particular embodiments disclosed herein are illustrative only and are not limiting to the scope of the invention which is to be given the full breadth of the claims, and any and all equivalents thereof, unless otherwise indicated herein, since various modifications may be made in accordance with the teachings herein, and it is intended that the particular embodiments disclosed above be limited not by the details of the structure or design herein disclosed unless otherwise indicated in the claims.
In addition, the number of elements in the claims includes or at least unless otherwise indicated, unless a term or phrase is used in the text that differs from the usage or meaning in the text that is otherwise defined , then the term or phrase should be read as defined in the text.

Claims (13)

1, A portable therapeutic assistance system, comprising:
an electrode adapted to be operatively affixed to a patient and adapted to provide an electric and/or magnetic field to a target region within the patient;
a three-dimensional positioning device adapted to provide a scheme of placement locations and number of electrodes from DICOM data of a patient; and
a wear-assist component adapted to assist in affixing the electrode to a patient according to the protocol.
2. The portable therapy assistance system of claim 1 wherein said three-dimensional positioning means comprises:
the anatomical structure imaging image processing module is used for receiving DICOM data of a patient and carrying out image segmentation on the DICOM data to obtain segmented data;
the multi-modal image processing module is arranged to import the segmentation data and convert the segmentation data into grid reconstruction data through a grid division algorithm so as to form three-dimensional grid reconstruction modeling data of a target area/target area in the body of the patient;
the multi-physical-field simulation model module is set to establish an electric field and/or magnetic field intensity optimization solving model according to the electric field and/or magnetic field intensity requirement required by the target region in the body of the patient; and
and the optimization solving module is arranged to introduce the received three-dimensional gridding reconstruction modeling data formed by the multi-modal image processing module into the electric field and/or magnetic field intensity optimization solving model, and solve the scheme to obtain the placement positions and the number of the electrodes.
3. The portable therapeutic assistance system of claim 2 wherein said three-dimensional positioning means comprises: comprising a data receiving and transmitting device, a data storage device, a display and a processor, wherein the processor executes computer instructions to execute the operations of the anatomical imaging image processing module, the multi-modal image processing module, the multi-physical field simulation model module and the optimization solution module.
4. The portable therapeutic assistance system of claim 2 wherein said optimization solution module is configured to solve for at least of said solutions.
5. The portable therapeutic assistance system of claim 4 wherein said optimization solution module is configured to solve for at least two of said protocols in which the respective electrode placement locations are different.
6. The portable therapy assistance system of claim 2, further comprising a 3D printout module adapted to print the wearable assistance component according to a scheme of placement locations and numbers of the electrodes.
7. The portable therapy assistance system of claim 6, wherein said printed wearable assistance component includes at least indicia thereon for indicating a placement location of said electrode.
8. The portable therapy assistance system of claim 7, wherein the electrode is mounted to the wearable assistance component according to the indicia.
9. The portable therapy assistance system of claim 7, wherein the electrodes are affixed to the patient's body surface according to indicia of the wearable assistance component.
10. The portable therapy assistance system of any of of claims 1-9, wherein the wear assistance component comprises a -th wear for the patient's head and/or a second wear for the patient's torso.
11. The portable therapeutic support system of claim 10, wherein said -th wearing member is in the shape of a cap or a pillow, and said second wearing member is in the shape of a chest-waist-abdomen patch, a chest-waist-abdomen circumference, or a pair of shorts.
12. The portable therapy assistance system of claim 10, wherein the wear assistance component is configured to be formed of a flexible material or a hard material.
13. The portable therapeutic assistance system of claim 12 wherein the flexible material or the rigid material is selected from the group consisting of or more of plastic, rubber, silicone, resin, nylon, and metal materials.
CN201810804515.5A 2018-07-20 2018-07-20 Portable treatment auxiliary system Pending CN110732087A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113827866A (en) * 2021-11-25 2021-12-24 北京航空航天大学杭州创新研究院 Non-invasive tumor treatment device based on alternating current electric field
CN115619808A (en) * 2022-10-31 2023-01-17 南京航空航天大学 Electrode plate attaching method and system

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113827866A (en) * 2021-11-25 2021-12-24 北京航空航天大学杭州创新研究院 Non-invasive tumor treatment device based on alternating current electric field
CN115619808A (en) * 2022-10-31 2023-01-17 南京航空航天大学 Electrode plate attaching method and system
CN115619808B (en) * 2022-10-31 2023-12-01 南京航空航天大学 Electrode slice attaching method and system

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