CN110672865A - In-vitro detection device, in-vitro detection method and in-vitro detection system - Google Patents
In-vitro detection device, in-vitro detection method and in-vitro detection system Download PDFInfo
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Abstract
The present disclosure relates to an in vitro detection apparatus, an in vitro detection method, and an in vitro detection system. The device includes: a card slot for inserting a detection card; the image acquisition unit is positioned above the card slot and used for detecting the reaction information of the marker on the detection card inserted into the card slot and identifying the graphic identification code on the detection card so as to acquire the basic information of the detection card; and the processing unit is used for acquiring the calibration parameters of the detection card according to the basic information and determining the detection result aiming at the target substance according to the calibration parameters and the reaction information. Therefore, the in-vitro detection device can automatically identify the basic information of the detection card, determine the calibration parameters of the detection card according to the basic information, calibrate the reaction information according to the calibration parameters, and avoid the defect that the target substance cannot be accurately detected due to different detection cards in each batch. Moreover, a user does not need to swipe an NFC card, the intellectualization of in vitro detection is greatly improved, and the use experience of the user is improved.
Description
Technical Field
The present disclosure relates to the field of detection technologies, and in particular, to an in vitro detection apparatus, an in vitro detection method, and an in vitro detection system.
Background
In the related regulation, the drug components detected by human hair samples are used as the important basis for the public security organization to identify drug taking. In current hair poison testing, the pre-treatment process is as follows, several hairs (e.g., hair) are cut, and the cut hairs are put into a solution. Then the suction tube is taken out, dropped on the detection card of the specific drug and then inserted into an in vitro detection device for detection.
The test card is actually a test paper inside, and at present, due to a problem of a production process of the test paper, it cannot be guaranteed that materials, contents, and the like of test papers of each batch are completely the same, so that each batch of test papers of each drug needs one batch of cards, the batch of cards can exist in the form of an NFC (Near Field Communication) card (hereinafter referred to as an NFC card), a specific drug type detected by the test paper and parameter information of the batch of test papers are stored in the NFC card, and the parameter information can include production batch codes, validity periods, and the like of the batch of test papers. Therefore, before each detection, a detection technician needs to find a corresponding batch card (NFC card) corresponding to the drug to brush, and can correctly detect the drug. This is a very cumbersome step for the test technician to operate. Particularly, when the number of the detection cards is large, situations that the NFC card cannot be found, the card is swiped by mistake or the NFC card is forgotten to be swiped often occur. Therefore, in the related art, the parameter information of the detection card cannot be accurately recognized, thereby causing a failure in accurately detecting the target substance to be detected.
Disclosure of Invention
The present disclosure is directed to an in vitro detection apparatus, an in vitro detection method, and an in vitro detection system, which are used to solve the problems of the related art.
In order to achieve the above object, the present disclosure provides an in vitro detection apparatus, comprising:
a card slot for inserting a detection card;
the image acquisition unit is positioned above the card slot and used for detecting reaction information of a marker on the detection card inserted into the card slot and identifying a graphic identification code on the detection card so as to acquire basic information of the detection card, wherein the basic information comprises the type of a target substance detected by the detection card and a production batch code of the detection card, and the reaction information is used for reflecting content information of the target substance;
and the processing unit is used for acquiring the calibration parameters of the detection card according to the basic information and determining the detection result aiming at the target substance according to the calibration parameters and the reaction information.
Optionally, the apparatus further comprises: the storage unit stores the corresponding relation between the basic information of the detection card and the calibration parameters;
the processing unit is configured to obtain the calibration parameter corresponding to the identified basic information according to the identified basic information and the correspondence stored in the storage unit.
Optionally, the apparatus further comprises: a communication unit in communication with a remote server;
the communication unit is used for sending the identified basic information to the remote server so that the remote server determines the calibration parameters corresponding to the identified basic information according to the basic information and the stored corresponding relationship between the basic information and the calibration parameters of the detection card;
the communication unit is further configured to receive the calibration parameter corresponding to the identified basic information sent by the remote server, and send the calibration parameter to the processing unit.
Optionally, the apparatus further comprises: a storage unit;
the processing unit is further used for storing the calibration parameters and the identified basic information in the storage unit in an associated mode.
Optionally, the communication unit is further configured to receive first prompt information sent by the remote server, where the first prompt information indicates that the remote server fails to determine the calibration parameter corresponding to the identified basic information;
the processing unit is further configured to output second prompt information when the communication unit receives the first prompt information, where the second prompt information is used to prompt a user to manually input the calibration parameters of the test card.
Optionally, the communication unit is further configured to send the detection result to the remote server.
Optionally, the image capturing unit includes a first camera and a second camera, wherein a mounting position of the first camera corresponds to a position of an observation window of the detection card inserted into the card slot, a mounting position of the second camera corresponds to a position of a graphic identification code on the detection card inserted into the card slot, the first camera is used for detecting the reaction information of the marker in the observation window, and the second camera is used for identifying the graphic identification code to obtain the basic information of the detection card.
Optionally, the reaction information comprises luminance information and/or area information.
Optionally, the apparatus is a handheld device.
Optionally, the apparatus further comprises: and the display unit is used for displaying the detection result.
The second aspect of the present disclosure also provides an in vitro detection method, comprising:
detecting reaction information of a marker on a detection card inserted into the card slot, wherein the reaction information is used for reflecting content information of a target substance detected by the detection card;
identifying the graphic identification information on the detection card to acquire basic information of the detection card, wherein the basic information comprises the type of the target substance detected by the detection card and a production batch code of the detection card;
acquiring calibration parameters of the detection card according to the basic information;
and determining a detection result aiming at the target substance according to the calibration parameters and the reaction information.
Optionally, the obtaining the calibration parameter of the detection card according to the basic information includes:
and acquiring the calibration parameters corresponding to the identified basic information according to the identified basic information and the corresponding relation between the basic information of the detection card and the calibration parameters.
Optionally, the obtaining the calibration parameter of the detection card according to the basic information includes:
sending the identified basic information to a remote server, so that the remote server determines the calibration parameters corresponding to the identified basic information according to the basic information and the stored corresponding relationship between the basic information of the detection card and the calibration parameters;
receiving the calibration parameters corresponding to the identified basic information sent by the remote server.
Optionally, the calibration parameters and the identified basic information are stored in association.
Optionally, the method further comprises:
receiving first prompt information sent by the far-end server, wherein the first prompt information represents that the far-end server fails to determine the calibration parameters corresponding to the identified basic information;
and under the condition of receiving the first prompt message, outputting a second prompt message, wherein the second prompt message is used for prompting a user to manually input the calibration parameters of the detection card.
Optionally, the method further comprises:
and sending the detection result to the remote server.
Optionally, the reaction information comprises luminance information and/or area information.
Optionally, the method further comprises:
and displaying the detection result.
The third aspect of the present disclosure also provides an in vitro detection system, comprising: the in vitro detection device provided by the first aspect of the present disclosure, wherein an observation window and a pattern identification code are arranged on the detection card, a marker is arranged in the observation window, the marker is used for reacting with the target substance to detect the content information of the target substance, and the pattern identification code is used for recording the basic information of the detection card.
According to the technical scheme, when the detection card is inserted into the card slot, the image acquisition unit detects the reaction information of the marker on the detection card and identifies the graphic identification code on the detection card to acquire the basic information of the detection card, and the processing unit acquires the calibration parameters of the detection card according to the basic information and determines the detection result aiming at the target substance according to the calibration parameters and the reaction information. Therefore, the in-vitro detection device can automatically identify the basic information of the detection card, determine the calibration parameters of the detection card according to the basic information, calibrate the reaction information according to the calibration parameters, and avoid the defect that the target substance cannot be accurately detected due to different detection cards in each batch. And, because external detection device can automatic identification detect the basic information of card, need not the user and swipes the NFC card, very big promotion external detection's intellectuality, improve user's use and experience, can also avoid the detection error that leads to because of the human factor.
Additional features and advantages of the disclosure will be set forth in the detailed description which follows.
Drawings
The accompanying drawings, which are included to provide a further understanding of the disclosure and are incorporated in and constitute a part of this specification, illustrate embodiments of the disclosure and together with the description serve to explain the disclosure without limiting the disclosure. In the drawings:
FIG. 1 is a schematic diagram illustrating a test card according to an exemplary embodiment.
FIG. 2 is a schematic diagram illustrating an extracorporeal detection apparatus according to an exemplary embodiment.
FIG. 3 is a schematic diagram illustrating a handheld extracorporeal detection apparatus according to an exemplary embodiment.
Fig. 4 is a schematic diagram illustrating an image capture unit and detector card position according to an exemplary embodiment.
FIG. 5 is a schematic diagram illustrating an extracorporeal detection apparatus according to another exemplary embodiment.
FIG. 6 is a flow chart illustrating a method of in vitro testing according to an exemplary embodiment.
FIG. 7 is a block diagram illustrating an electronic device in accordance with an example embodiment.
FIG. 8 is a block diagram illustrating an electronic device in accordance with another example embodiment.
Detailed Description
The following detailed description of specific embodiments of the present disclosure is provided in connection with the accompanying drawings. It should be understood that the detailed description and specific examples, while indicating the present disclosure, are given by way of illustration and explanation only, not limitation.
Before describing the in-vitro test device provided by the present disclosure in detail, a test card suitable for the in-vitro test device will be described first. FIG. 1 is a schematic diagram illustrating a test card according to an exemplary embodiment. As shown in fig. 1, the detection card 10 includes a detection card housing 101 and a detection test strip 102, the detection test strip 102 is located in the detection card housing 101, the detection test strip 102 includes at least one detection line 103 (two lines are shown in fig. 1) made of a marker, and an observation window 104 is opened at a position of the detection line 103. The observation window is used for a detection technician or detection equipment to acquire reaction information of the marker and the target substance. A graphic identification code 105 is laser-engraved or printed on the test card housing 101, and the graphic identification code 105 is used for recording basic information of the test card 10. The basic information may include the type of target substance detected by the test card and the production lot code of the test card.
Further, as shown in fig. 1, a sampling window 106 is opened at a position a predetermined distance away from the observation window 104 side (left side in fig. 1). During the detection, the user or the technician drops the solution to be detected into the sampling window 106, and soaks the solution to be detected on the test paper 102 toward the detection line 103 of the observation window 104. If the solution to be detected contains the target substance, the labeled substance on the detection line 103 reacts with the target substance, so that the detection line 103 changes, for example, the color of the detection line 103 changes to red, or the detection line 103 emits light, etc. Thus, whether or not the target substance is contained in the solution to be detected can be detected by detecting the change of the detection line 103 in the card 10.
Next, an extracorporeal detection apparatus provided by the present disclosure and fitted with the above-described detection card will be described.
Referring to fig. 2, fig. 2 is a schematic diagram of an extracorporeal detection apparatus according to an exemplary embodiment. As shown in fig. 2, the in-vitro test device 20 may include: card slot 201, image acquisition unit 202, processing unit 203.
The card slot 201 is used for inserting a detection card. The image acquisition unit 202 is located above the card slot 201 and is configured to detect reaction information of a marker on a detection card inserted into the card slot 201 and identify a graphic identification code on the detection card to obtain basic information of the detection card, where the basic information of the detection card includes a type of a target substance detected by the detection card and a production lot code of the detection card, and the reaction information is used to represent content information of the target substance.
The label on the detection card may be a fluorescent label, a colloidal gold label, a colloidal selenium label, or the like, which is not limited in this disclosure. The graphic identification code can be a two-dimensional code or a bar code, and the like, wherein the graphic identification code is laser engraved or printed on the detection card when the detection card is shipped. The type of the target substance may be Human blood glucose, HIV Virus (Human Immunodeficiency Virus), rabies Virus, or drug type, etc., and the disclosure is not particularly limited thereto.
It should be noted that the observation window 104 and the graphic identification code 105 on the test card are both located within the capture range of the image capture unit 202, so that when the test card is inserted into the card slot 201, the image capture unit 202 can detect the reaction information of the marker on the test card and recognize the graphic identification code on the test card to obtain the basic information of the test card.
The processing unit 203 is configured to obtain a calibration parameter of the detection card according to the basic information, and determine a detection result for the target substance according to the calibration parameter and the reaction information. The calibration parameter may be represented in the form of a calibration curve, or may be represented in a number, which is not specifically limited by the present disclosure.
Generally, when a detection card (test paper) with different materials and/or contents is used for detecting the target substance with the same content, the obtained detection results are different. For example, if the content of the fluorescent marker in the test card of lot a is higher than that of the fluorescent marker in the test card of lot B, and the same content of the target substance is detected by using the test cards of lot a and the test cards of lot B, respectively, the luminance of the fluorescent marker in the test card of lot a is higher than that of the fluorescent marker in the test card of lot B. That is, the detection results of different batches of detection cards for the same content of target substance are different, and thus, the detection of the target substance may be inaccurate. Specifically, the content of the fluorescent marker in the detection card of batch B is low, and when the detection card of batch B is used to detect the solution to be detected containing the target substance, the brightness of the fluorescent marker is low, the concentration of the corresponding target substance is low, even the brightness of the fluorescent marker is low, so that a technician cannot recognize the brightness, thereby resulting in that the target substance is missed to be detected, and the solution to be detected is considered to include no target substance. Illustratively, the luminance of the fluorescent marker was 5cd/m when the concentration of the target substance reached 10mol/L for the lot A of the detection cards2And when the concentration of the target substance in the detection card of the batch B reaches 20mol/L, the brightness of the fluorescent marker is 5cd/m2Thus, if the technician only depends on the brightness of the marker, 5cd/m2When the concentration of the target substance was determined, it was not possible to distinguish whether the concentration of the target substance was 10mol/L or 20mol/L, and, when the detection was carried out using the detection card of lot B, since the concentration was less than 20mol/L, the luminance of the fluorescent marker did not reach the preset luminance of 5cd/m2I.e. the solution to be detected is considered to contain no target substance.
In order to avoid the problem that the target substance cannot be accurately detected or the content of the target substance cannot be accurately detected due to the production process technology, in the present disclosure, the processing unit 203 obtains the calibration parameter of the detection card according to the basic information, and determines the detection result for the target substance according to the calibration parameter and the reaction information.
Specifically, in order to enable different batches of test cards to test the target substance with the same standard, a calibration parameter is set for each test card, wherein the calibration parameters of the test cards in the same batch are the same. Thus, even if the content of the marker in the lot a test card is high and the content of the marker in the lot B test card is low, the detection result of the lot a test card and the detection result of the lot B test card can be consistent for the same content of the target substance by setting different calibration parameters. Wherein the calibration parameters are set by a technician through multiple trials, or empirically, and the disclosure is not particularly limited thereto.
By adopting the technical scheme, when the detection card is inserted into the card slot, the image acquisition unit detects the reaction information of the marker on the detection card and identifies the graphic identification code on the detection card to obtain the basic information of the detection card, and the processing unit obtains the calibration parameters of the detection card according to the basic information and determines the detection result aiming at the target substance according to the calibration parameters and the reaction information. Therefore, the in-vitro detection device can automatically identify the basic information of the detection card, determine the calibration parameters of the detection card according to the basic information, calibrate the reaction information according to the calibration parameters, and avoid the defect that the target substance cannot be accurately detected due to different detection cards in each batch. And, because external detection device can automatic identification detect the basic information of card, need not the user and swipes the NFC card, very big promotion external detection's intellectuality, improve user's use and experience, can also avoid the detection error that leads to because of the human factor.
In addition, the in-vitro detection apparatus 20 may be a handheld device, and the handheld device may be, for example, a mobile terminal, a notebook computer, a desktop computer, etc., as shown in fig. 3, taking the in-vitro detection apparatus 20 as the mobile terminal as an example, a card slot opening is formed on a side of the mobile terminal, as shown in fig. 3, through which the detection card 10 may be inserted into the card slot. It should be noted that the image acquisition unit 202 and the processing unit 203 are located inside the mobile terminal, and are not shown in the figure.
Alternatively, in one embodiment, the image capturing unit 202 is a camera, and the mounting position of the camera corresponds to the position of the viewing window and the graphic identification code on the test card inserted into the card slot 201, i.e., the viewing window and the graphic identification code on the test card are located within the shooting range of the camera. Therefore, the camera can detect the reaction information of the marker in the observation window and can also identify the graphic identification code to acquire the basic information of the detection card.
In another embodiment, as shown in fig. 4, the image capturing unit 202 may include two cameras, namely a first camera 2021 and a second camera 2022, wherein the first camera 2021 is installed at a position corresponding to the position of the viewing window 104 of the test card 10 inserted into the card slot, the second camera 2022 is installed at a position corresponding to the position of the graphic identification code 105 on the test card 10 inserted into the card slot, the first camera 2021 is used for detecting the reaction information of the marker in the viewing window 104, and the second camera 2022 is used for identifying the graphic identification code 105 to obtain the basic information of the test card.
In this embodiment, it is possible that, when the test card 10 is inserted into the card slot, the first camera 2021 and the second camera 2022 are turned on, wherein the first camera 2021 detects the reaction information of the marker in the observation window 104, and the second camera 2022 recognizes the graphic identification code 105 to acquire the basic information of the test card 10. Another possible situation is that when the test card 10 is inserted into the card slot 201, the second camera 2022 is turned on, and at this time, the first camera 2021 does not work, and the second camera 2022 works normally to recognize the graphic identification code 105 on the test card 10 to obtain the basic information of the test card 10, and sends the basic information to the processing unit 203, so that the processing unit 203 can obtain the calibration parameters of the test card according to the basic information. After the processing unit 203 acquires the calibration parameters of the detection card 10, the second camera 2022 is turned off, and the first camera 2021 turns on the reaction information of the marker in the detection observation window 104. That is, after the calibration parameters of the detection card are acquired, the first camera 2021 is started to detect the reaction information of the marker in the observation window 104, so that the workload of the first camera can be reduced, and the service life of the first camera can be prolonged.
After the image acquisition unit 202 acquires the basic information of the test card, the processing unit 203 may acquire the calibration parameters of the test card according to the basic information. In one embodiment, the processing unit 203 may obtain the calibration parameters locally from the extracorporeal detection apparatus 20. Specifically, as shown in fig. 5, the in-vitro detection device 20 may further include: a storage unit 204, wherein the storage unit 204 stores the corresponding relation between the basic information of the detection card and the calibration parameter. In this embodiment, the processing unit 203 is configured to obtain the calibration parameters corresponding to the identified basic information according to the basic information identified by the image acquisition unit 202 and the corresponding relationship stored in the storage unit 204.
In another embodiment, the processing unit 203 may further acquire the calibration parameters from a remote location. Specifically, as shown in fig. 5, the in-vitro detection device 20 may further include: the communication unit 205, which is in communication with the remote server, correspondingly stores the corresponding relationship between the basic information of the detection card and the calibration parameters. In this embodiment, the communication unit 205 is configured to send the basic information identified by the image acquisition unit 202 to the remote server, so that the remote server determines the calibration parameters corresponding to the identified basic information according to the basic information and the stored corresponding relationship between the basic information of the detection card and the calibration parameters.
In general, on one hand, the storage space in the storage unit is much smaller than the storage space of the remote server, and on the other hand, the communication range of the remote server is large, and when the detection card leaves the factory, a technician mostly stores the corresponding relationship between the basic information and the calibration parameters of the detection card in the remote server, so the number of the corresponding relationships between the basic information and the calibration parameters of the detection card stored in the storage unit is much smaller than the number of the corresponding relationships stored in the remote server. That is, in another embodiment, if there is no correspondence between the basic information of the detection card and the calibration parameter in the storage unit, the correspondence between the basic information of the detection card and the calibration parameter may also be obtained from a remote server. In particular, the extracorporeal detection apparatus may further include both the storage unit 204 and the communication unit 205. When the processing unit 203 does not acquire the calibration parameters corresponding to the identified basic information from the storage unit 204, the communication unit 205 may further transmit the identified basic information to the remote server, so that the remote server determines the calibration parameters corresponding to the identified basic information according to the basic information and the stored correspondence between the basic information of the detection card and the calibration parameters.
In the above embodiment, after the remote server determines the calibration parameter corresponding to the identified basic information, the remote server may further send the calibration parameter to the communication unit 205, so that the communication unit 205 sends the calibration parameter to the processing unit 203, and the processing unit 203 may further be configured to store the calibration parameter and the identified basic information in the storage unit 204 in an associated manner, so as to enrich the corresponding relationship between the basic information of the detection card and the calibration parameter stored in the storage unit 204. Further, the remote server may further send the correspondence between the basic information and the calibration parameters of all the detection cards stored by the remote server to the processing unit 203 through the communication unit 205, and correspondingly, the processing unit 203 may store the correspondence between the basic information and the calibration parameters of all the detection cards to the storage unit 204. It should be noted that, because the storage space of the storage unit 204 is limited, in the present disclosure, for each detection card, the storage unit 204 only stores the corresponding relationship between the basic information and the calibration parameter of the detection card, and the storage is not repeated.
In general, the remote server stores the corresponding relationship between the basic information and the calibration parameters of each shipped detection card, that is, the remote server can search the calibration parameters of any shipped detection card. However, in practical applications, there is a possibility that the corresponding relationship between the basic information and the calibration parameters of some of the test cards may be missed to store, so that the calibration parameters of the test cards cannot be found in the remote server.
Specifically, the communication unit 205 is further configured to receive first prompt information sent by a remote server, where the first prompt information indicates that the remote server fails to determine a calibration parameter corresponding to the identified basic information. Accordingly, the processing unit 203 is further configured to output a second prompt message for prompting the user to manually input the calibration parameters of the test card if the communication unit 205 receives the first prompt message.
By adopting the technical scheme, the calibration parameters can be obtained locally or remotely, so that the flexibility of in vitro detection can be improved. And when the calibration parameters are not acquired from the far end, prompt information can be output to prompt a user to manually input the calibration parameters of the detection card so as to realize the detection of the target substance.
After acquiring the calibration parameter of the detection card and the reaction information of the marker on the detection card, the processing unit 203 determines the detection result for the target substance according to the calibration parameter and the reaction information. The response information may include brightness information and/or area information. After the calibration parameter is obtained, the processing unit 203 adds the brightness value and/or the area value corresponding to the brightness information and/or the area information to the value corresponding to the calibration parameter, so as to obtain a calibrated brightness value and/or area value, and then determines the detection result for the target substance based on the calibrated brightness value and/or area value. The value corresponding to the calibration parameter may be a positive number or a negative number.
For example, it is assumed that the response information may include brightness information, the brightness information is an average brightness value of the mark line collected by the first camera, and the calibration parameter is a brightness calibration valueAnd the content of the fluorescent marker in the test cards of the batch A is higher than the standard content by a fixed value, and when the test cards of the batch A are delivered from a factory, a technician sets the brightness calibration value of the test cards of the batch A to be-2 cd/m according to experience2The average luminance value of the fluorescent marker in the test card of lot A acquired by the processing unit 203 was 10cd/m2Thus, the processing unit 203 may take the sum of the luminance and the luminance calibration value as the calibrated luminance value, i.e. 8cd/m in terms of the luminance2It is determined whether the target substance is contained, and the content of the target substance. How to determine the content of the target substance according to the brightness of the marker belongs to the prior art, and is not described herein again.
Further, for example, based on the above example, assuming that the content of the fluorescent marker in the test cards of lot B is lower than the standard content by a fixed value, when the test cards of lot B are shipped from factory, the technician empirically sets the luminance calibration value of the test cards of lot B to be 2cd/m2Thus, when the same solution to be detected is detected by the detection card of lot A, the luminance of the fluorescent marker in the detection card of lot B can be acquired by the processing unit 203 as 6cd/m2And obtaining the calibrated brightness value of 8cd/m according to the brightness calibration value of the detection card of the batch B2And further according to the luminance 8cd/m2It is determined whether the target substance is contained, and the content of the target substance. Thus, by adopting the technical scheme, even if the detection cards with different annotations are used for detecting the target substance with the same content, the same detection result can be obtained, and the reliability of the detection result of the detection device for detecting the target substance is improved.
It should be noted that, if the calibration parameter is represented in the form of a calibration curve, the reaction information acquired by the processing unit 203 is the labeled luminance curve, so that a preset calibration curve is superimposed on the luminance curve to obtain a calibrated luminance curve, and the detection result for the target substance is determined according to the calibrated luminance curve.
After the detection result for the target substance is determined, the detection result can be displayed, so that a user can conveniently view the detection result. The in-vitro detection device can also comprise a display unit, and the display unit is used for displaying the detection result.
In addition, after determining the detection result for the target substance, the communication unit 205 may further transmit the detection result to a remote server to store the detection result for the target substance in the remote server for subsequent viewing.
Based on the same inventive concept, the present disclosure also provides an in vitro detection method. FIG. 6 is a flow chart illustrating a method of in vitro testing according to an exemplary embodiment. As shown in fig. 6, the method may include:
in step 61, reaction information of the marker on the detection card inserted into the card slot is detected, and the reaction information is used for reflecting content information of the target substance detected by the detection card.
In step 62, the graphic identification information on the test card is identified to obtain basic information of the test card, wherein the basic information includes the type of the target substance detected by the test card and the production lot code of the test card.
In step 63, calibration parameters of the test card are obtained based on the basic information.
In step 64, the detection result for the target substance is determined based on the calibration parameters and the reaction information.
It should be noted that, the step 61 and the step 62 may be executed simultaneously, or the step 62 may be executed first and then the step 61 is executed, or the step 61 may be executed first and then the step 62 is executed, and the disclosure is not limited in detail.
Optionally, the obtaining the calibration parameter of the detection card according to the basic information includes:
and acquiring the calibration parameters corresponding to the identified basic information according to the identified basic information and the corresponding relation between the basic information of the detection card and the calibration parameters.
Optionally, the obtaining the calibration parameter of the detection card according to the basic information includes:
sending the identified basic information to a remote server, so that the remote server determines the calibration parameters corresponding to the identified basic information according to the basic information and the stored corresponding relationship between the basic information of the detection card and the calibration parameters;
receiving the calibration parameters corresponding to the identified basic information sent by the remote server.
Optionally, the calibration parameters and the identified basic information are stored in association.
Optionally, the method further comprises:
receiving first prompt information sent by the far-end server, wherein the first prompt information represents that the far-end server fails to determine the calibration parameters corresponding to the identified basic information;
and under the condition of receiving the first prompt message, outputting a second prompt message, wherein the second prompt message is used for prompting a user to manually input the calibration parameters of the detection card.
Optionally, the method further comprises:
and sending the detection result to the remote server.
Optionally, the reaction information comprises luminance information and/or area information.
Optionally, the method further comprises:
and displaying the detection result.
With regard to the method in the above-described embodiment, the specific manner in which each step is performed has been described in detail in the embodiment related to the method, and will not be described in detail herein.
FIG. 7 is a block diagram illustrating an electronic device in accordance with an example embodiment. As shown in fig. 7, the electronic device 700 is provided as an in vitro detection apparatus, and may include: a processor 701 and a memory 702. The electronic device 700 may also include one or more of a multimedia component 703, an input/output (I/O) interface 704, and a communication component 705.
The processor 701 is configured to control the overall operation of the electronic device 700, so as to complete all or part of the steps in the in-vitro detection method. The memory 702 is used to store various types of data to support operation at the electronic device 700, such as instructions for any application or method operating on the electronic device 700 and application-related data, such as contact data, transmitted and received messages, pictures, audio, video, and the like. The Memory 702 may be implemented by any type of volatile or non-volatile Memory device or combination thereof, such as Static Random Access Memory (SRAM), Electrically Erasable Programmable Read-Only Memory (EEPROM), Erasable Programmable Read-Only Memory (EPROM), Programmable Read-Only Memory (PROM), Read-Only Memory (ROM), magnetic Memory, flash Memory, magnetic disk, or optical disk. The multimedia components 703 may include screen and audio components. Wherein the screen may be, for example, a touch screen and the audio component is used for outputting and/or inputting audio signals. For example, the audio component may include a microphone for receiving external audio signals. The received audio signal may further be stored in the memory 702 or transmitted through the communication component 705. The audio assembly also includes at least one speaker for outputting audio signals. The I/O interface 704 provides an interface between the processor 701 and other interface modules, such as a keyboard, mouse, buttons, etc. These buttons may be virtual buttons or physical buttons. The communication component 705 is used for wired or wireless communication between the electronic device 700 and other devices. Wireless communication, such as Wi-Fi, bluetooth, Near Field Communication (NFC), 2G, 3G, 4G, NB-IOT, eMTC, or other 5G, etc., or a combination of one or more of them, which is not limited herein. The corresponding communication component 705 may thus include: Wi-Fi module, Bluetooth module, NFC module, etc.
In an exemplary embodiment, the electronic Device 700 may be implemented by one or more Application Specific Integrated Circuits (ASICs), Digital Signal Processors (DSPs), Digital Signal Processing Devices (DSPDs), Programmable Logic Devices (PLDs), Field Programmable Gate Arrays (FPGAs), controllers, microcontrollers, microprocessors, or other electronic components for performing the in vitro detection method described above.
In another exemplary embodiment, a computer readable storage medium comprising program instructions for implementing the steps of the in vitro detection method described above when executed by a processor is also provided. For example, the computer readable storage medium may be the memory 702 described above comprising program instructions executable by the processor 701 of the electronic device 700 to perform the in vitro detection method described above.
Fig. 8 is a block diagram illustrating an electronic device 800 in accordance with another example embodiment. For example, the electronic device 800 may be provided as a remote server. Referring to fig. 8, an electronic device 800 includes a processor 822, which may be one or more in number, and a memory 832 for storing computer programs executable by the processor 822. The computer programs stored in memory 832 may include one or more modules that each correspond to a set of instructions. Further, the processor 822 may be configured to execute the computer program to perform the steps of: and determining a calibration parameter corresponding to the identified basic information according to the basic information of the calibration card and the stored corresponding relationship between the basic information of the detection card and the calibration parameter, and sending the calibration parameter to a communication unit of the in-vitro detection device.
Additionally, the electronic device 800 may also include a power component 826 and a communication component 850, the power component 826 may be configured to perform power management of the electronic device 800, and the communication component 850 may be configured to enable communication, e.g., wired or wireless communication, of the electronic device 800. The electronic device 800 may also include input/output (I/O) interfaces 858. The electronic device 800 may operate based on an operating system stored in the memory 832, such as Windows Server, Mac OSXTM, UnixTM, LinuxTM, and the like.
In another exemplary embodiment, a computer readable storage medium is further provided, which includes program instructions, when executed by a processor, for implementing the above-mentioned steps of determining a calibration parameter corresponding to the identified basic information according to the basic information of the calibration card and the stored correspondence between the basic information of the test card and the calibration parameter, and transmitting the calibration parameter to the communication unit of the extracorporeal test apparatus. For example, the computer readable storage medium may be the memory 832 comprising program instructions executable by the processor 822 of the electronic device 800 to perform the steps of determining calibration parameters corresponding to the identified basic information and transmitting the calibration parameters to the communication unit of the extracorporeal detection apparatus according to the basic information of the calibration card and the stored correspondence between the basic information of the detection card and the calibration parameters.
In another exemplary embodiment, a computer program product is also provided, which comprises a computer program executable by a programmable apparatus, the computer program having code portions for performing the above-mentioned steps of determining a calibration parameter corresponding to the identified basic information based on the basic information of the calibration card and the stored correspondence between the basic information of the test card and the calibration parameter, and transmitting the calibration parameter to a communication unit of the extracorporeal test apparatus, when the computer program is executed by the programmable apparatus.
Based on the same inventive concept, the present disclosure also provides an in vitro detection system, comprising: the present disclosure provides a detection card and an in vitro detection apparatus. As shown in fig. 1, the detection card is provided with an observation window and a pattern identification code, the observation window is provided with a marker, the marker is used for reacting with a target substance to detect content information of the target substance, and the pattern identification code is used for recording the basic information of the detection card.
The preferred embodiments of the present disclosure are described in detail with reference to the accompanying drawings, however, the present disclosure is not limited to the specific details of the above embodiments, and various simple modifications may be made to the technical solution of the present disclosure within the technical idea of the present disclosure, and these simple modifications all belong to the protection scope of the present disclosure.
It should be noted that the various features described in the above embodiments may be combined in any suitable manner without departing from the scope of the invention. In order to avoid unnecessary repetition, various possible combinations will not be separately described in this disclosure.
In addition, any combination of various embodiments of the present disclosure may be made, and the same should be considered as the disclosure of the present disclosure, as long as it does not depart from the spirit of the present disclosure.
Claims (13)
1. An in vitro test device, comprising:
a card slot for inserting a detection card;
the image acquisition unit is positioned above the card slot and used for detecting reaction information of a marker on the detection card inserted into the card slot and identifying a graphic identification code on the detection card so as to acquire basic information of the detection card, wherein the basic information comprises the type of a target substance detected by the detection card and a production batch code of the detection card, and the reaction information is used for reflecting content information of the target substance;
and the processing unit is used for acquiring the calibration parameters of the detection card according to the basic information and determining the detection result aiming at the target substance according to the calibration parameters and the reaction information.
2. The in vitro test device of claim 1, further comprising: the storage unit stores the corresponding relation between the basic information of the detection card and the calibration parameters;
the processing unit is configured to obtain the calibration parameter corresponding to the identified basic information according to the identified basic information and the correspondence stored in the storage unit.
3. The in vitro test device of claim 1, further comprising: a communication unit in communication with a remote server;
the communication unit is used for sending the identified basic information to the remote server so that the remote server determines the calibration parameters corresponding to the identified basic information according to the basic information and the stored corresponding relationship between the basic information and the calibration parameters of the detection card;
the communication unit is further configured to receive the calibration parameter corresponding to the identified basic information sent by the remote server, and send the calibration parameter to the processing unit.
4. The in vitro test device of claim 3, further comprising: a storage unit;
the processing unit is further used for storing the calibration parameters and the identified basic information in the storage unit in an associated mode.
5. The in-vitro detection apparatus according to claim 3, wherein the communication unit is further configured to receive a first prompt message sent by the remote server, the first prompt message indicating that the remote server fails to determine the calibration parameter corresponding to the identified basic information;
the processing unit is further configured to output second prompt information when the communication unit receives the first prompt information, where the second prompt information is used to prompt a user to manually input the calibration parameters of the test card.
6. The in-vitro detection device according to claim 3, wherein the communication unit is further configured to transmit the detection result to the remote server.
7. The in-vitro detection device according to claim 1, wherein the image acquisition unit comprises a first camera and a second camera, wherein the first camera is installed at a position corresponding to a position of a viewing window of the detection card inserted into the card slot, the second camera is installed at a position corresponding to a position of a graphic identification code on the detection card inserted into the card slot, the first camera is used for detecting the reaction information of the marker in the viewing window, and the second camera is used for identifying the graphic identification code to obtain basic information of the detection card.
8. The in-vitro detection device according to claim 1, wherein the response information comprises brightness information and/or area information.
9. The in vitro test device of claim 1, wherein the device is a handheld device.
10. An in vitro assay method, comprising:
detecting reaction information of a marker on a detection card inserted into the card slot, wherein the reaction information is used for reflecting content information of a target substance detected by the detection card;
identifying the graphic identification information on the detection card to acquire basic information of the detection card, wherein the basic information comprises the type of the target substance detected by the detection card and a production batch code of the detection card;
acquiring calibration parameters of the detection card according to the basic information;
and determining a detection result aiming at the target substance according to the calibration parameters and the reaction information.
11. The in-vitro detection method according to claim 10, wherein the obtaining calibration parameters of the detection card according to the basic information comprises:
sending the identified basic information to a remote server, so that the remote server determines the calibration parameters corresponding to the identified basic information according to the basic information and the stored corresponding relationship between the basic information of the detection card and the calibration parameters;
receiving the calibration parameters corresponding to the identified basic information sent by the remote server.
12. The in vitro assay of claim 11, further comprising:
receiving first prompt information sent by the far-end server, wherein the first prompt information represents that the far-end server fails to determine the calibration parameters corresponding to the identified basic information;
and under the condition of receiving the first prompt message, outputting a second prompt message, wherein the second prompt message is used for prompting a user to manually input the calibration parameters of the detection card.
13. An in vitro test system, comprising: the in vitro test device of any one of claims 1 to 9 and a test card, wherein the test card is provided with a viewing window and a pattern identification code, the viewing window is provided with a marker, the marker is used for reacting with the target substance to test the content information of the target substance, and the pattern identification code is used for recording the basic information of the test card.
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