CN110367363A - Radix Astragali bubble boils dedicated medicine materical crude slice and preparation method thereof - Google Patents

Radix Astragali bubble boils dedicated medicine materical crude slice and preparation method thereof Download PDF

Info

Publication number
CN110367363A
CN110367363A CN201910800986.3A CN201910800986A CN110367363A CN 110367363 A CN110367363 A CN 110367363A CN 201910800986 A CN201910800986 A CN 201910800986A CN 110367363 A CN110367363 A CN 110367363A
Authority
CN
China
Prior art keywords
radix astragali
materical crude
medicine materical
crude slice
bubble
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201910800986.3A
Other languages
Chinese (zh)
Inventor
孙军伟
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Gansu Guolikang Traditional Chinese Medicine R & D Co Ltd
Original Assignee
Gansu Guolikang Traditional Chinese Medicine R & D Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gansu Guolikang Traditional Chinese Medicine R & D Co Ltd filed Critical Gansu Guolikang Traditional Chinese Medicine R & D Co Ltd
Priority to CN201910800986.3A priority Critical patent/CN110367363A/en
Publication of CN110367363A publication Critical patent/CN110367363A/en
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23FCOFFEE; TEA; THEIR SUBSTITUTES; MANUFACTURE, PREPARATION, OR INFUSION THEREOF
    • A23F3/00Tea; Tea substitutes; Preparations thereof
    • A23F3/34Tea substitutes, e.g. matè; Extracts or infusions thereof

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The invention discloses a kind of Radix Astragali bubble, boil dedicated medicine materical crude slice and preparation method thereof, Radix Astragali of the present invention bubble boils dedicated medicine materical crude slice by using screening, reel off raw silk from cocoons, the manufacture craft of compression forming, diameter 3cm is compressed into tea cake compression special purpose machinery, with a thickness of the small tea cake of 1.0cm-1.2cm, Radix Astragali bubble, the effective component boiled in dedicated medicine materical crude slice silk are adequately retained, the nutritional ingredient and effect that cracking can be volatilized its Radix Astragali bubble in brew process, boil dedicated medicine materical crude slice.It improves Radix Astragali bubble, boil the quality and effect of dedicated medicine materical crude slice, and using disinfection and strictly be packaged into bag, so that Radix Astragali bubble, boiling dedicated medicine materical crude slice and being more easier to store and transport, the popularization for steeping, boiling dedicated medicine materical crude slice convenient for Radix Astragali is drunk.

Description

Radix Astragali bubble boils dedicated medicine materical crude slice and preparation method thereof
Technical field
The present invention relates to tea-drinking and agricultural product technical field more particularly to a kind of Radix Astragali bubble, boil dedicated medicine materical crude slice and its preparation Method.
Background technique
Radix Astragali is a kind of common Chinese medicine, has invigorating qi for strengthening superficies, diuresis, heart tonifying, decompression, antibacterial, eliminating toxic, apocenosis, life Flesh reinforces the effect of capillary resistance, hidroschesis and class sex hormone.Other than medicinal, also it is frequently used for eating, for example make tea It is soaked.
However nowadays, in the market not using Radix Astragali as the beverage of teas, according to the habit of the diet of people and culture It is used, the purposes such as common Radix Astragali slice is used to make tea by most people, Baoshang, to reach health and fill blood and other effects.And it is this All place of origin are indefinite mostly for slice, and processing technology is simple, generally all sold the most in medicinal material specialized market with bulk goods on the market It is common, it does not remove the peel, select since Radix Astragali is sliced, cause to contain a large amount of pesticide residue and all kinds of impurity in Radix Astragali slice, In, have rotten discoloration, partial decomposition, numb mouth, digging injury speckle with soil, have place for a long time damaged by worms, etc., and Due to not having to carry out the specific processing flow of product and specific packaging, to Radix Astragali notch, (Radix Astragali is crosscutting in transport and storage process Face) secondary pollution is carried out, many defective products are generated, injury can be directly contributed to human body by directly drinking this product.To human health Aspect has many negative effects, the quality and effect for affecting Radix Astragali bubble to a certain extent, boiling dedicated medicine materical crude slice.
In addition, existing similar products further include the products such as Radix Astragali tabletting, astragalus membranaceus powder, but the customer group of these products is big It is all mostly pharmaceutical factory and Chinese herbalist clinic etc., the degree directly drunk is not achieved in product itself, is also not achieved pollution-free no added Food degree.Since Radix Astragali slice does not decompose original shape state Radix Astragali, concocted time is very long, needs at least two hours 50% or so of Radix Astragali nutritional ingredient, Radix Astragali slice and the brewed nutritional ingredient and content for not going out Radix Astragali in the short time can be bubbled out, and There is no the processes such as disinfection and sterilization;The teas directly drunk popularization is not easy to drink.
Summary of the invention
An object of the present invention, in that the preparation method that a kind of Radix Astragali bubble is provided, boils dedicated medicine materical crude slice, it is above-mentioned to solve Problem.
To achieve the goals above, the technical solution adopted by the present invention is that it is such:
A kind of Radix Astragali steeps, boils the preparation method of dedicated medicine materical crude slice, comprising the following steps:
(1) original shape state Radix Astragali is taken, debranching end to end is removed, obtains Radix Astragali knot;
(2) the resulting Radix Astragali knot of step (1) is cleaned, filters out substandard products and defective products, then remove the peel, obtains Radix Astragali core;Clearly Mode is washed preferably individually to be cleaned by each of man-hour manually hand-held brush;This step, which eliminates contained by Radix Astragali appearance, to be owned Pesticide residue and all impurity, only retaining Radix Astragali fuse is to process raw material;The substandard products, which refer to, numb mouth, rotten, naturally corruption Rotten Radix Astragali;The defective products refers to the Radix Astragali of discoloration;
(3) by the resulting Radix Astragali core tearing of step (2) at Radix Astragali silk;
(4) the resulting Radix Astragali silk of step (3) is compressed into tea cake;
(5) the resulting tea cake of step (4) is dry, sterilization, pack to get.Before packaging, the tea cake hair not suppressed preferably is wiped out Then side is packed again.When packaging, it is preferred that point three layers of packaging: it is first layer packet that first layer, which selects the linen-cotton paper sterilized, Dress, it is intended to prevent worker's direct body contact's product during the packaging process, to Radix Astragali bubble, boil dedicated medicine materical crude slice and bring impurity or various Bacterium;The second layer be sterilization after transparent plastic bottle, with 2 tea cakes be a bottle, carry out bottling sealing;Third layer is outer layer Packing box.
Radix Astragali of the invention steeps, boils dedicated medicine materical crude slice, is different from existing Radix Astragali slicing mode, is with original shape state Radix Astragali fuse Radix Astragali silk after decomposition is mainly to process raw material, and according to specific factors such as season or constitutions, cooperates different food materials and integration of drinking and medicinal herbs The purpose of teabag drink that product are researched and developed jointly, reaches invigorating qi for consolidating superficies in a manner of drinking tea, strengthening exterior and reducing sweat, inducing diuresis for removing edema, shengjin nourishing. The present invention, which passes through the bubble of the Radix Astragali after decomposing that reels off raw silk from cocoons, boils dedicated medicine materical crude slice then can leach 50% left side of Radix Astragali nutritional ingredient in 2-5 minute It is right.In addition, resulting Radix Astragali bubble can be made by the screening operation such as substandard products and defective products, sterilization, dedicated medicine materical crude slice is boiled and reach direct The quality drunk safely.Radix Astragali bubble is boiled dedicated medicine materical crude slice and is processed in a manner of tea cake after reeling off raw silk from cocoons and decomposing compacting, diameter and thickness Degree can reach independent packaging requirement, and independent packaging is advantageous in that each product is not in contact with each other, and carry out between product Mutually packaging isolation and be manually isolated, so do not allow it is perishable, go bad, tea cake surface and product itself will not be caused repeatedly Pollution and injury.In addition, every diameter is up between 0.5-1.5 compared to traditional astragalus mongholicus tablet, with a thickness of 3-6mm, and For bulk goods, can not independent packaging, product and product be naked to be suffered at one piece and is particularly easy to large area after having a humid climate and rot, shape Shape and size are uneven, and of the invention Radix Astragali bubble boils dedicated medicine materical crude slice and is more easier to store and transport.
As a preferred technical solution, in step (1), the original shape state Radix Astragali is to take between height above sea level 2000m-2300m Hillside band Radix Astragali, constituency is mostly that place of production periphery is hillside and natural grassy marshland at high mountain mountain top.
The above-mentioned preferably fresh Radix Astragali taken is as raw material, it is of course also possible to use dried not sliced Huang Stilbene medicinal material is as raw material.
As a preferred technical solution, in step (1), the Radix Astragali knot is pricked for a bundle with iron wire with 20-25 Well at bundle, naturally dry.
It is first bundled into primarily to Radix Astragali can be very good to classify so as to peeling, and raw material root according to diameter Portion's diameter is bigger, and price is higher, and is bundled into can preferably lock nutritional ingredient, and single branch sunning nutritional ingredient is easy stream It loses.Drying rear cleaning purpose is for bored profit, convenient for peeling.
As a preferred technical solution, in step (2), the substandard products, which refer to, numb mouth, Huang that is rotten, naturally rotting Stilbene;The defective products refers to the Radix Astragali of discoloration.
As a preferred technical solution, in step (3), by the way of manually tearing.
According to tear(ing) strength, be divided into three grades: superfine, i.e. tearing diameter is less than 1mm, makes tea drink mainly as boiled water With;Level-one, i.e. tearing diameter 1-2mm, brew mainly as boiling water and drink;Second level, i.e. tearing diameter 2-3mm, as Baoshang, are boiled Soup is dedicated.
As a preferred technical solution, in step (4), compressed using tea cake compressor.
As further preferred technical solution, pressure when compression is 40 tons of weight.
As a preferred technical solution, in step (4), the diameter of single tea cake is 3cm, a height of 1cm-1.2cm, weight are 3g-4g.By the way of then compacting tea cake of reeling off raw silk from cocoons, and suitable tea cake size is selected, in favor of nutritional ingredient to be retained in In tea cake, and brew time is short, so that nutrition is more preferably brought into play faster.
Because according to correlation standard, the personal Radix Astragali day amount of drinking is no more than 9g, this product suggestion amount of drinking 2 daily Piece, not more than 8g, therefore every sheet weight must not be higher than 4.5g here.
As a preferred technical solution, in step (5), drying to the aqueous mass percent of tea cake is lower than 7%.It can ensure Radix Astragali bubble, the quality and quality for boiling dedicated medicine materical crude slice.
As a preferred technical solution, in step (5), method for disinfection is ultraviolet sterilization, and the time preferably sterilized is 20min-30min。
The second object of the present invention is to provide a kind of using Radix Astragali above-mentioned bubble, boils the preparation method system of dedicated medicine materical crude slice Standby obtained Radix Astragali bubble boils dedicated medicine materical crude slice.
Radix Astragali bubble, the drinking method for boiling dedicated medicine materical crude slice are as follows: one piece of tea cake taken, is put into cup, 8-10 fructus lyciis are put into, With 10g-20g honey, 250ml or so boiled water is poured into, it is i.e. capable of direct drinking after 2-5 minutes brewed.
Compared with the prior art, the advantages of the present invention are as follows:
1. Radix Astragali of the invention steeps, boils dedicated medicine materical crude slice using original shape state Radix Astragali core as primary raw material, on the basis of debranching, cleaning, Radix Astragali is removed the peel completely, is decomposed, and is added without any auxiliary material, it is without any side effects, it can significantly improve body heath, improve Body immunity enhances function of human body;
2. Radix Astragali of the invention steeps, boils dedicated medicine materical crude slice by using the manufacture craft of compression forming, so that Radix Astragali steeps, boils dedicated drink Effective component in piece can adequately be retained, and improved Radix Astragali bubble, boiled the quality and effect of dedicated medicine materical crude slice, and make this Radix Astragali bubble boils dedicated medicine materical crude slice and is more easier to store and transport, and drinks convenient for Radix Astragali bubble, the popularization for boiling dedicated medicine materical crude slice;
3. Radix Astragali of the invention steeps, boils dedicated medicine materical crude slice due to preferably having carried out multi-layer packaging, and in storage, transport and selling period Between product itself will not be polluted and be injured.Make Radix Astragali bubble, boil dedicated medicine materical crude slice more clean hygiene.
4. Radix Astragali of the invention steeps, boils dedicated medicine materical crude slice since Radix Astragali has been gone decomposition and compression, make constituents extraction in Huang Stilbene bubble boils inside dedicated medicine materical crude slice cake, in brew process, can quickly dissolve, soak out all Radix Astragali content and nutritional ingredient.
Specific embodiment
Below in conjunction with embodiment, the invention will be further described.
Embodiment:
A kind of Radix Astragali steeps, boils the preparation method of dedicated medicine materical crude slice cake comprising following steps:
(1) the high-quality Radix Astragali debranching between (Minxian County) local height above sea level 2000m-2300m is taken into section, cuts into Radix Astragali knot;
(2) Radix Astragali knot is tied for a bundle with iron wire with 20-25 and is made into Radix Astragali bundle, placed natural at shady and cool, dry It dries;
(3) the Radix Astragali knot after drying manually is cleaned up by root, and each Radix Astragali section is removed the peel, and choosing has Ma Kou, day The unqualified substandard products such as so rotting, digging injury and the defective products such as discoloration, rotten, the Radix Astragali fuse after retaining peeling, this process All pesticide residues and all impurity contained by Radix Astragali appearance are eliminated, Radix Astragali fuse is only retained;
(4) Radix Astragali fuse is manually torn and resolves into Radix Astragali silk;
(5) Radix Astragali silk is pressed into Radix Astragali bubble with 40 tons of weight with tea cake compressor, boils dedicated medicine materical crude slice cake, by compression moulding, Nutritional ingredient is extracted and is retained in monolith tea cake;
(6) it is pressed into diameter 3cm, the Radix Astragali bubble of thickness 1.0cm-1.2cm boils dedicated medicine materical crude slice cake, and every piece of weight is 3g-4g, and Pick out the unqualified substandard products not suppressed;
(7) finished product is placed on shady and cool dry and ventilated place naturally to dry, mass dryness fraction maintains 93% or more;
(8) finished product packing is most carried out after ultraviolet radiation for sterilizing and disinfecting 20min-30min afterwards;
(9) three layers of packaging point.It is first layer packaging that first layer, which selects the linen-cotton paper sterilized, it is intended to prevent worker in packaging process Middle direct body contact's Radix Astragali bubble boils dedicated medicine materical crude slice, brings impurity or various bacteriums to product itself;The second layer is after sterilizing Transparent plastic bottle is one bottle with 2 tea cakes and carries out bottling sealing;Third layer is external packing box.Obtain " Radix Astragali bubble, boil it is dedicated Medicine materical crude slice cake ".
One piece of " Radix Astragali bubble boils dedicated medicine materical crude slice cake " in the present embodiment, is taken, is put into cup, is put into 8-10 fructus lyciis, be added 10g-20g honey pours into 250ml boiled water, i.e. capable of direct drinking after 2-5 minutes brewed.
Comparative example:
For this comparative example by the way of traditional Radix Astragali slice, the source of crude drug is still same as Example 1, picks up from Minxian County Between local height above sea level 2000m-2300m, kind and collecting time are also identical, and only subsequent treatment process is different;It will take Fresh Radix Astragali remove soil impurity, cut reed head, shine or ventilation is dried in the shade to doing very likely, then cut off lateral root and fibrous root, Radix Astragali knot is obtained, inclined tab is then cut, with a thickness of 3mm or so, is then dried, " Radix Astragali medicine materical crude slice " is obtained.
Contrasting detection example:
The present embodiment using embodiment 1 resulting " Radix Astragali bubble, boil dedicated medicine materical crude slice cake " and comparative example resulting " Radix Astragali slice " as Test sample carries out following items detection respectively:
1. detecting Astragaloside IV using TLC method:
Detection method: " Radix Astragali bubble boils dedicated medicine materical crude slice cake " and " Radix Astragali slice " each 3g are taken respectively, adds methanol 20ml, is heated to reflux 1 Hour, filtration, filtrate is added on neutral alumina column (100-120 mesh, 5g, internal diameter 10-15mm), is washed with 40% methanol 100ml It is de-, eluent is collected, is evaporated, residue adds water 30ml to make to dissolve, and the n-butanol shaking being saturated with water is extracted 2 times, each 20ml, closes And n-butanol liquid, it being washed with water 2 times, each 20ml, discards aqueous, n-butanol liquid is evaporated, and residue adds methanol 0.5ml to make to dissolve, As test solution.Astragaloside IV reference substance separately is taken, adds methanol 1ml the is made solution containing 1mg, as reference substance solution.According to Thin-layered chromatography (Chinese Pharmacopoeia version general rule 0502 in 2015) test, draws each 2 μ l of above two solution, puts same silica gel respectively On G lamellae, using lower layer's solution of chloroform-methanol-water (13:7:2) as solvent, it is unfolded, takes out, dry, spray with 10% Ethanol solution of sulfuric acid, it is clear to be heated to spot development at 105 DEG C, in sample chromatogram, in position corresponding with reference substance chromatography On, identical sepia spot is shown under daylight;Identical orange-yellow fluorescence spot is shown under ultraviolet light (365nm).
2. detecting main component using TLC method
" Radix Astragali bubble, boil dedicated medicine materical crude slice cake " and " Radix Astragali slice " each 2g are taken respectively, respectively plus ethyl alcohol 30ml, are heated to reflux 20 points Clock, filtration, filtrate is evaporated, and residue adds 0.3% sodium hydroxide solution 15ml to make to dissolve, filtration, filtrate with dilute hydrochloric acid adjust pH value to 5 ~ 6, it is shaken and is extracted with ethyl acetate 15ml, divided and take acetic acid ethyl fluid, filtered with the filter paper for being covered with appropriate anhydrous sodium sulfate, filtrate It is evaporated.Residue adds ethyl acetate 1ml to make to dissolve, as test solution.Radix Astragali control medicinal material 2g separately is taken, is made in the same way of comparison medicine Material solution is tested according to thin-layered chromatography (Chinese Pharmacopoeia general rule 0502 in 2015), draws each 10 μ l of above two solution, respectively point On same silica gel g thin-layer plate, with chloroform-methanol (10:1) for solvent, it is unfolded, takes out, dry, set in ammonia steam and smoke Afterwards, it sets and is inspected under ultraviolet light (365nm), in sample chromatogram, on position corresponding with reference medicine chromatography, show identical face The fluorescence principal spot of color.
3. water content detection
It must not exceed 10% referring to (2015 editions general rules of Chinese Pharmacopoeia, 0,832 second method) detection Radix Astragali moisture.It is done according to this measurement Method, " Radix Astragali slice " testing result are as follows: 8%-10%;" Radix Astragali bubble boils dedicated medicine materical crude slice cake " is 5%-7%.Use side of the invention The bubble of Radix Astragali made from method boils dedicated medicine materical crude slice, and moisture content is lower, is easier to preservation.
4. total ash detects
Referring to (Chinese Pharmacopoeia version general rule 2302 in 2015) requirement, total ash must not exceed 5.0%, testing result, " Radix Astragali slice " Total ash is 4.0-5.0%, and " Radix Astragali bubble boils dedicated medicine materical crude slice cake " total ash is 2.5-3.6%.
5. heavy metal and harmful element measurement
Referring to (Chinese Pharmacopoeia 2321 atomic absorption spectrophotometries of version general rule in 2015 or the law popularization of inductively coupled plasma constitution) Heavy metal and harmful element measurement, lead must not cross 5mg/kg, cadmium must not cross 0.3mg/kg, arsenic must not cross 2mg/kg, mercury must not mistake 0.2mg/kg, copper must not cross 20mg/kg.
Method, " Radix Astragali slice " testing result are as follows: lead 4.2-5mg/kg, cadmium 0.2-0.3mg/kg, arsenic 1- are measured according to this 2mg/kg, mercury must not cross 0.1-0.2mg/kg, copper 18-20mg/kg;" Radix Astragali bubble boils dedicated medicine materical crude slice cake " testing result are as follows: lead 3- 4mg/kg, cadmium 0.1-0.2mg/kg, arsenic 0.8-1.2mg/kg, mercury must not cross 0.1-0.2mg/kg, copper 12-14mg/kg.
The content of proof use method of the invention, heavy metal and harmful element obtains tightened up control, and safety is more It is high.
6. pesticide residue determination
It is surveyed referring to (Chinese Pharmacopoeia 2341 the-the first method of Organochlorine Pesticide Residues measuring method of version general rule in 2015) pesticide residue determination method Fixed, six six six (total BHC) must not cross 0.2mg/kg;DDT (total DDT) must not cross 0.2mg/kg;Pentachloronitrobenzene (PCNB) 0.1mg/kg must not be crossed.
Method, " Radix Astragali slice " testing result are as follows: six six six (total BHC) 0.1-0.2mg/kg are measured according to this;DDT (total DDT) 0.1-0.2mg/kg;Pentachloronitrobenzene (PCNB) 0.08-0.1mg/kg;" Radix Astragali bubble boils dedicated medicine materical crude slice cake " detection As a result are as follows: six six six (total BHC) 0.06-1.0mg/kg;DDT (total DDT) 0.06-0.1mg/kg;Pentachloronitrobenzene (PCNB) 0.02-0.04mg/kg.
It proves to use method of the invention, pesticide residue obtains tightened up control, and content is lower.
7. sulfur dioxide residual quantity measures
It is measured referring to (Chinese Pharmacopoeia version general rule 2331 in 2015) sulfur dioxide residual quantity measuring method, 10mg/kg must not be crossed.
Method, " Radix Astragali slice " testing result are as follows: 8-10mg/kg are measured according to this;" Radix Astragali bubble boils dedicated medicine materical crude slice cake " inspection Survey result are as follows: 3-5mg/kg.
It proves to use method of the invention, the content of sulfur dioxide is lower.
8. water-soluble extractives measure
It is measured referring to (Chinese Pharmacopoeia version general rule 2201 in 2015) water-soluble extractives measuring method (cold-maceration), standard, which must not be, to be lacked In 20.0%.
Method, " Radix Astragali slice " testing result are as follows: (2-5 minutes) 1-8% are measured according to this;" Radix Astragali bubble boils dedicated medicine materical crude slice Cake " testing result are as follows: 25-30%.
9. the leaching situation of Astragaloside IV measures
Referring to (Chinese Pharmacopoeia version general rule 0512 in 2015) HPLC measuring method, recorded in version Radix Astragali standard with Chinese Pharmacopoeia 2015 C18 column, acetonitrile: water (32:68) be mobile phase, evaporative light scattering detector,
The qualitative and quantitative detection for further carrying out ingredient using above-mentioned HPLC for the 8th extract, the results show that " Radix Astragali Slice ": after 2-5 minutes cold soakings, not detecting Astragaloside IV in extract, in other words not up to detection limit, further It is impregnated 2-5 minutes using boiling water, obtains hot extract, there is the Astragaloside IV of 5-8% or so, i.e. " Radix Astragali slice " in hot extract In Astragaloside IV, only 5-8% by boiling water leach and be present in hot extract (first detect " Radix Astragali slice " in contain in total Astragaloside IV, then detect the Astragaloside IV in extract, impregnate 2 minutes and only leach 5% or so, impregnate that leach 8% within 5 minutes left It is right),
And for " Radix Astragali bubble boils dedicated medicine materical crude slice cake ": after cold soaking 2-5 minutes, the Radix Astragali first of 10-13% has been leached in cold extract Glycosides after boiling water impregnates 2-5 minutes, has the Astragaloside IV of 60-75%, i.e., in " Radix Astragali bubble boils dedicated medicine materical crude slice cake " in hot extract Astragaloside IV has 60-75% to be leached and be present in hot extract by boiling water.
10. the leaching situation of calycosin glucoside measures
Referring to (Chinese Pharmacopoeia version general rule 0512 in 2015) HPLC measuring method, recorded in version Radix Astragali standard with Chinese Pharmacopoeia 2015 C18 column, acetonitrile be mobile phase A, 0.2% formic acid solution be Mobile phase B, gradient elution, elution program referring to pharmacopeia 2015 editions, Detection wavelength 260nm;
The qualitative and quantitative detection for further carrying out ingredient using above-mentioned HPLC for the 8th extract, the results show that " Radix Astragali Slice ": after 2-5 minutes cold soakings, not detecting calycosin glucoside in extract, in other words not up to detection Limit is further impregnated 2-5 minutes using boiling water, obtains hot extract, there is the calycosin Portugal of 3-9% or so in hot extract Polyglycoside, i.e. calycosin glucoside in " Radix Astragali slice ", only 3-9% are leached by boiling water and are present in hot extract In (the calycosin glucoside first contained in total in detection " Radix Astragali slice ", then detect the calycosin in extract Glucoside impregnates 2 minutes and only leaches 3% or so, impregnates 5 minutes and leaches 9% or so),
And for " Radix Astragali bubble boils dedicated medicine materical crude slice cake ": after cold soaking 2-5 minutes, the Mao Ruiyi of 25-35% has been leached in cold extract Flavones glucoside has the calycosin glucoside of 60-70%, i.e. " Radix Astragali after boiling water impregnates 2-5 minutes in hot extract Steep, boil dedicated medicine materical crude slice cake " in calycosin glucoside, have 65-80% by boiling water leach and be present in hot extract.
As it can be seen that principle active component Astragaloside IV and calycosin glucose using method of the invention, in Radix Astragali The leaching velocity and leaching integrity degree of glycosides are significantly improved, to be conducive to take.
The foregoing is merely illustrative of the preferred embodiments of the present invention, is not intended to limit the invention, all in essence of the invention Made any modifications, equivalent replacements, and improvements etc., should all be included in the protection scope of the present invention within mind and principle.

Claims (10)

1. a kind of Radix Astragali bubble, the preparation method for boiling dedicated medicine materical crude slice, which comprises the following steps:
(1) original shape state Radix Astragali is taken, debranching end to end is removed, obtains Radix Astragali knot;
(2) the resulting Radix Astragali knot of step (1) is cleaned, filters out substandard products and defective products, then remove the peel, obtains Radix Astragali core;
(3) by the resulting Radix Astragali core tearing of step (2) at Radix Astragali silk;
(4) the resulting Radix Astragali silk of step (3) is compressed into Radix Astragali tea cake;
(5) the resulting tea cake of step (4) is dry, sterilization, pack to get.
2. Radix Astragali bubble according to claim 1, the preparation method for boiling dedicated medicine materical crude slice, which is characterized in that in step (1), institute Stating original shape state Radix Astragali is the hillside band Radix Astragali taken between height above sea level 2000m-2300m, and constituency is mostly place of production week at high mountain mountain top Side is hillside and natural grassy marshland.
3. Radix Astragali bubble according to claim 1, the preparation method for boiling dedicated medicine materical crude slice, which is characterized in that, will in step (1) The Radix Astragali knot ties into bundle with iron wire for a bundle with 20-25, naturally dries.
4. Radix Astragali bubble according to claim 1, the preparation method for boiling dedicated medicine materical crude slice, which is characterized in that in step (3), adopt The mode manually torn.
5. Radix Astragali bubble according to claim 1, the preparation method for boiling dedicated medicine materical crude slice, which is characterized in that in step (4), adopt It is compressed with tea cake compressor.
6. Radix Astragali bubble according to claim 5, the preparation method for boiling dedicated medicine materical crude slice, which is characterized in that pressure when compression For 40 tons of weight.
7. Radix Astragali bubble according to claim 1, the preparation method for boiling dedicated medicine materical crude slice, which is characterized in that single in step (4) The diameter of a tea cake is 3cm, a height of 1cm-1.2cm, weight 3g-4g.
8. Radix Astragali bubble according to claim 1, the preparation method for boiling dedicated medicine materical crude slice, which is characterized in that in step (5), do It is dry to the aqueous mass percent of tea cake be lower than 7%.
9. Radix Astragali bubble according to claim 1, the preparation method for boiling dedicated medicine materical crude slice, which is characterized in that in step (5), kill Bacterium method is ultraviolet sterilization, and the time preferably sterilized is 20min-30min.
10. using Radix Astragali described in any one of claim 1-9 bubble, boiling the Radix Astragali that the preparation method of dedicated medicine materical crude slice is prepared It steeps, boil dedicated medicine materical crude slice.
CN201910800986.3A 2019-08-28 2019-08-28 Radix Astragali bubble boils dedicated medicine materical crude slice and preparation method thereof Pending CN110367363A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201910800986.3A CN110367363A (en) 2019-08-28 2019-08-28 Radix Astragali bubble boils dedicated medicine materical crude slice and preparation method thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201910800986.3A CN110367363A (en) 2019-08-28 2019-08-28 Radix Astragali bubble boils dedicated medicine materical crude slice and preparation method thereof

Publications (1)

Publication Number Publication Date
CN110367363A true CN110367363A (en) 2019-10-25

Family

ID=68261041

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201910800986.3A Pending CN110367363A (en) 2019-08-28 2019-08-28 Radix Astragali bubble boils dedicated medicine materical crude slice and preparation method thereof

Country Status (1)

Country Link
CN (1) CN110367363A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111887325A (en) * 2020-08-19 2020-11-06 岷县盛尚中药材有限责任公司 Astragalus health tea and processing method thereof

Citations (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1443553A (en) * 2002-03-12 2003-09-24 李小海 Bagged Chinese medicine pieces prepared for decoction and its preparation method
CN101229219A (en) * 2007-01-23 2008-07-30 上海德华国药制品有限公司 Technology of processing astragalus root decoction pieces
CN101703136A (en) * 2009-11-03 2010-05-12 林炳光 Method for preparing orange peel tea
CN102885877A (en) * 2011-07-22 2013-01-23 岷县顺兴和中药材有限责任公司 Hand cutting processing method for astragalus decoction pieces
CN104173421A (en) * 2014-08-19 2014-12-03 浙江尖峰健康科技有限公司 Radix astragali decoction piece and preparation method thereof
CN104622944A (en) * 2013-11-12 2015-05-20 呼和浩特市通瑞科技有限责任公司 Method for processing Radix Astragali decoction pieces in producing area
CN104784247A (en) * 2015-04-20 2015-07-22 安徽精诚本草中药饮片有限公司 Processing method of astragalus membranaceus decoction block
CN104873454A (en) * 2015-04-03 2015-09-02 邹宇聪 TCM cakes containing single Chinese herbs and powders of TCM set prescription
CN105267288A (en) * 2015-11-16 2016-01-27 刘发元 Processing method of radix astragali decoction pieces
CN106074674A (en) * 2016-08-29 2016-11-09 王彦春 A kind of processing method of Radix Astragali decoction pieces
CN106265870A (en) * 2016-08-08 2017-01-04 湖南盟合投资管理有限公司 The preparation method of Radix Astragali breaking cellular wall decoction pieces
CN106306233A (en) * 2016-02-20 2017-01-11 武熙熙 Nutritive rosa roxburghii tratt substitutional tea and making method thereof
CN106706634A (en) * 2016-05-21 2017-05-24 广州今典精方药业有限公司 Quality standard and preparation process of qualitative and quantitative Chinese herbal astragali radix decoction slice
CN107753549A (en) * 2017-10-12 2018-03-06 刘王 A kind of preparation method of the Radix Astragali prepared slices of Chinese crude drugs
CN108210552A (en) * 2018-03-08 2018-06-29 蔺君 A kind of production method of the Radix Astragali prepared slices of Chinese crude drugs
CN108310029A (en) * 2018-04-04 2018-07-24 安徽颐生堂中药饮片有限公司 A kind of windproof medicine materical crude slice and its concocting method
CN109432137A (en) * 2018-12-28 2019-03-08 山东饶益生物科技有限公司 The preparation method of the prepared slices of Chinese crude drugs
CN109965057A (en) * 2019-04-25 2019-07-05 周爱莲 A kind of flower of kudzuvine tea cake
CN110115722A (en) * 2019-04-18 2019-08-13 苏州市春晖堂药业有限公司 A kind of Radix Astragali ultramicro decoction piece and its processing technology

Patent Citations (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1443553A (en) * 2002-03-12 2003-09-24 李小海 Bagged Chinese medicine pieces prepared for decoction and its preparation method
CN101229219A (en) * 2007-01-23 2008-07-30 上海德华国药制品有限公司 Technology of processing astragalus root decoction pieces
CN101703136A (en) * 2009-11-03 2010-05-12 林炳光 Method for preparing orange peel tea
CN102885877A (en) * 2011-07-22 2013-01-23 岷县顺兴和中药材有限责任公司 Hand cutting processing method for astragalus decoction pieces
CN104622944A (en) * 2013-11-12 2015-05-20 呼和浩特市通瑞科技有限责任公司 Method for processing Radix Astragali decoction pieces in producing area
CN104173421A (en) * 2014-08-19 2014-12-03 浙江尖峰健康科技有限公司 Radix astragali decoction piece and preparation method thereof
CN104873454A (en) * 2015-04-03 2015-09-02 邹宇聪 TCM cakes containing single Chinese herbs and powders of TCM set prescription
CN104784247A (en) * 2015-04-20 2015-07-22 安徽精诚本草中药饮片有限公司 Processing method of astragalus membranaceus decoction block
CN105267288A (en) * 2015-11-16 2016-01-27 刘发元 Processing method of radix astragali decoction pieces
CN106306233A (en) * 2016-02-20 2017-01-11 武熙熙 Nutritive rosa roxburghii tratt substitutional tea and making method thereof
CN106706634A (en) * 2016-05-21 2017-05-24 广州今典精方药业有限公司 Quality standard and preparation process of qualitative and quantitative Chinese herbal astragali radix decoction slice
CN106265870A (en) * 2016-08-08 2017-01-04 湖南盟合投资管理有限公司 The preparation method of Radix Astragali breaking cellular wall decoction pieces
CN106074674A (en) * 2016-08-29 2016-11-09 王彦春 A kind of processing method of Radix Astragali decoction pieces
CN107753549A (en) * 2017-10-12 2018-03-06 刘王 A kind of preparation method of the Radix Astragali prepared slices of Chinese crude drugs
CN108210552A (en) * 2018-03-08 2018-06-29 蔺君 A kind of production method of the Radix Astragali prepared slices of Chinese crude drugs
CN108310029A (en) * 2018-04-04 2018-07-24 安徽颐生堂中药饮片有限公司 A kind of windproof medicine materical crude slice and its concocting method
CN109432137A (en) * 2018-12-28 2019-03-08 山东饶益生物科技有限公司 The preparation method of the prepared slices of Chinese crude drugs
CN110115722A (en) * 2019-04-18 2019-08-13 苏州市春晖堂药业有限公司 A kind of Radix Astragali ultramicro decoction piece and its processing technology
CN109965057A (en) * 2019-04-25 2019-07-05 周爱莲 A kind of flower of kudzuvine tea cake

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
刘晓庆等: "不同来源、不同等级黄芪饮片中毛蕊异黄酮葡萄糖苷含量分析", 《药物分析杂志》 *
汪祺等: "黄芪中氨基酸、黄酮类成分的特征薄层图谱鉴别", 《中国药事》 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111887325A (en) * 2020-08-19 2020-11-06 岷县盛尚中药材有限责任公司 Astragalus health tea and processing method thereof

Similar Documents

Publication Publication Date Title
JP6716671B2 (en) Composition for making tea beverage or herb broth and vegetable broth
CN103907707B (en) Momordica grosvenori clearing lung type tea and preparation method thereof
Govindarajan et al. Pepper—chemistry, technology, and quality evaluation
CN104106692A (en) Buckwheat tea bag and preparation method thereof
CN104970133A (en) Silkworm cocoon shell containing tea containing products, tea substitute drinks, or traditional Chinese medicine drink tablets, and preparation method and use thereof
CN101999503A (en) Cordyceps glossy ganoderma teabag and making method thereof
CN108782895A (en) One cultivate peanut leaf sleeping alternative tea preparation and method for pouring
CN106798061A (en) Jerusalem artichoke leaf tea and preparation method thereof
CN104996623B (en) Tea bag obstructs tea and preparation method thereof
CN113925903A (en) Sichuan tangerine peel and preparation method thereof
CN110367363A (en) Radix Astragali bubble boils dedicated medicine materical crude slice and preparation method thereof
KR101140325B1 (en) Composition of mixed herb medicine for leached tea
KR101198122B1 (en) Composition of leached tea containing purple corn and the method of manufacturing thereof
CN108743817A (en) Rhizoma Gastrodiae antistaling agent and preparation method thereof and its application in Rhizoma Gastrodiae is fresh-keeping
CN103893239A (en) Preparation method of heterophylly falsestarwort root slices
CN107183246A (en) A kind of fragrance of a flower is calmed the nerves blood-pressure decreasing tea and preparation method thereof
CN104106690A (en) Barley tea juice blended buckwheat teabag and preparation method thereof
KR100859324B1 (en) Method for manufacturing the health beverage utilizing extraction of sarcodon aspratus
CN109170046A (en) A kind of tea extraction capsule and preparation method thereof
CN105030855B (en) A kind of prevention and cure of cardiovascular disease, hyperlipemia health protection tea and preparation method thereof and detection method
CN107149633B (en) Assorted vine tea and preparation method and application thereof
KR100404921B1 (en) Method for making a korean herb tea with effect for improving amnesia
CN107969533A (en) A kind of processing method of honeysuckle tea
KR101557063B1 (en) Paper using red ginseng grounds
CN106721848A (en) A kind of hypotensive defatted wheat germ bag bubble solid beverage and preparation method thereof

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
RJ01 Rejection of invention patent application after publication

Application publication date: 20191025

RJ01 Rejection of invention patent application after publication