CN110353298A - Electronic cigarette liquid - Google Patents

Electronic cigarette liquid Download PDF

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Publication number
CN110353298A
CN110353298A CN201910816296.7A CN201910816296A CN110353298A CN 110353298 A CN110353298 A CN 110353298A CN 201910816296 A CN201910816296 A CN 201910816296A CN 110353298 A CN110353298 A CN 110353298A
Authority
CN
China
Prior art keywords
electronic cigarette
cigarette liquid
liquid
content
naringenin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201910816296.7A
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Chinese (zh)
Inventor
许静
姜兴涛
熊赞华
李馨铎
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Shenzhen Relx Technology Co Ltd
Original Assignee
Shenzhen Relx Technology Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shenzhen Relx Technology Co Ltd filed Critical Shenzhen Relx Technology Co Ltd
Priority to CN201910816296.7A priority Critical patent/CN110353298A/en
Publication of CN110353298A publication Critical patent/CN110353298A/en
Priority to PCT/CN2019/127156 priority patent/WO2021036121A1/en
Pending legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A24TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24BMANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
    • A24B15/00Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
    • A24B15/10Chemical features of tobacco products or tobacco substitutes
    • A24B15/16Chemical features of tobacco products or tobacco substitutes of tobacco substitutes
    • AHUMAN NECESSITIES
    • A24TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24BMANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
    • A24B15/00Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
    • A24B15/10Chemical features of tobacco products or tobacco substitutes
    • A24B15/16Chemical features of tobacco products or tobacco substitutes of tobacco substitutes
    • A24B15/167Chemical features of tobacco products or tobacco substitutes of tobacco substitutes in liquid or vaporisable form, e.g. liquid compositions for electronic cigarettes

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  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

This application involves a kind of electronic cigarette liquids.The embodiment of the present application provides a kind of electronic cigarette liquid, which includes naringenin, wherein content of the naringenin in the electronic cigarette liquid is calculated as 0.09% to 10% with the electronic cigarette liquid gross weight.The electronic cigarette liquid is by atomization, it includes naringenin can with tobacco juice be atomized come out, it is absorbed by the body, and then achievees the effect that anti-inflammatory, cough-relieving apophlegmatic and inhibit oral cavity and respiratory tract bacterium, and the mouthfeel after the electronic cigarette liquid can be made to be atomized is more comfortable, milder enriches the fragrance of cigarette, improves sucking quality.

Description

Electronic cigarette liquid
Technical field
This application involves the fields more particularly to a kind of electronic cigarette liquid of electronics aerosol or electronic atomization device.
Background technique
Traditional tobacco is sucked with many possible side effects, such as cardiovascular disease, cancer, chronic obstructive pulmonary disease Deng seriously endangering the health of human body.It is most direct for wherein smoking to the effect of respiratory system, and traditional tobacco is under high-temp combustion The harmful substance discharged can make the reduction of respiratory tract defense function, make goblet cell hyperplasia, mucilage secretion increases, cilia activity It is abnormal, lower mucus discharge function, so as to cause the various respiratories systemic disease such as pneumonia, chronic obstructive pulmonary disease.
The tar, suspended particulates and carbon monoxide to human health are not likely to produce by low-temperature atomizing in electronics tobacco tar Etc. harmful substances, harm is far smaller than harm of the conventional cigarette to human body user and caused by other people.
Therefore, by low-temperature atomizing how further to generate reduction be harmful to the human body influence and improve to human body beneficial effect The aerosol for user's sucking, be that electronics smoke product needs improved research direction.
Summary of the invention
The application is generated in the electronic cigarette liquid by atomising device by providing a kind of electronic cigarette liquid containing naringenin It is able to maintain the naringenin of certain content in aerosol for user's sucking, and then is absorbed by the body and plays a role in health care.When User can obtain the health-care effect of clearing heat and moistening lung, cough-relieving apophlegmatic when aspirating the electronic cigarette liquid simultaneously.
According to the application level, this application provides a kind of electronic cigarette liquids, and it includes naringenins, wherein the shaddock Content of the Pi Su in the electronic cigarette liquid is calculated as about 0.09% to about 10% with the electronic cigarette liquid gross weight.
According to another level of the application, this application provides a kind of atomising devices, and it includes above-mentioned electronic cigarette liquids.This Shen Electronic cigarette liquid please can play the role of inhibiting stomatitis, cough or prevention bacteria breed.
The additional level and advantage of the embodiment of the present application will be described partly in subsequent instruction, be shown or via this Apply for the implementation of embodiment and illustrates.
Detailed description of the invention
Figure 1A is the chromatogram according to the shaddock ped cellulose content of the electronic cigarette liquid of the embodiment of the present application.
Figure 1B is the chromatogram according to the shaddock ped cellulose content of the electronic cigarette liquid aerosol generated of the embodiment of the present application.
Specific embodiment
Embodiments herein will be shown hereinafter by detailed retouch.Embodiments herein does not answer described be interpreted Limitation to the application.
In addition, sometimes herein with range format presentation amount, ratio and other numerical value.It should be understood that such range format It is that and should neatly understand for convenient and for purpose of brevity, not only comprising being expressly specified as the numerical value of scope limitation, but also wraps Containing all individual numbers or the subrange being covered by the range, as explicitly specifying each numerical value and subrange.
As used herein, term " substantially ", " substantially ", " generally ", " essence " and " about " is to describe and illustrate Small variation.When being used in combination with event or situation, the term can be referred to the example that wherein event or situation accurately occur And the example that wherein event or situation pole approximatively occur.For example, when combination numerical value is in use, term can be referred to be less than Or ± 10% variation range equal to the numerical value, e.g., less than or equal to ± 5%, be less than or equal to ± 4%, be less than or wait In ± 3%, be less than or equal to ± 2%, be less than or equal to ± 1%, being less than or equal to ± 0.5%, being less than or equal to ± 0.1%, Or it is less than or equal to ± 0.05%.For example, if the difference between two values is less than or equal to the average value of described value ± 10% (e.g., less than or equal to ± 5%, be less than or equal to ± 4%, be less than or equal to ± 3%, be less than or equal to ± 2%, Less than or equal to ± 1%, it is less than or equal to ± 0.5%, is less than or equal to ± 0.1% or is less than or equal to ± 0.05%), that It is believed that described two numerical value " generally " are identical.
In specific embodiment and claims, by term at least one of at least one of " ", " ", " in At least one " or the list of project that is connected of other term similars may imply that any combination of listed item.For example, such as Fruit lists project A and B, then phrase " at least one of A and B " means only A;Only B;Or A and B.In another example, such as Fruit lists project A, B and C, then phrase " at least one of A, B and C " means only A;Or only B;Only C;A and B (excluding C); A and C (excluding B);B and C (excluding A);Or the whole of A, B and C.Project A may include discrete component or multiple element.Project B can Include discrete component or multiple element.Project C may include discrete component or multiple element.
Herein, term " aerosol for user's sucking " may include but being not limited to, aerosol, suspension liquid, Low-temperature steam and escaping gas.
The application provides a kind of electronic cigarette liquid containing naringenin, for the same of electronic cigarette liquid of the user after sucking atomization When can play anti-inflammatory, cough-relieving, resolving sputum and the multiple beneficials effect such as antibacterial.
According to the one aspect of the application, this application provides a kind of electronic cigarette liquid, it includes shaddock peds for the electronic cigarette liquid Element.
Naringenin have antibacterial, it is anti-inflammatory, remove that free radical, anti-oxidant, cough-relieving apophlegmatic, reducing blood lipid, anticancer be antitumor, spasmolysis With cholagogue, prevent and treat hepatopathy, inhibit coagulating platelets, resist the effects of athero- artery sclerosis.In some embodiments, work as electricity When sub- tobacco juice forms aerosol by atomising device, it includes naringenin can be mixed into aerosol by atomization together, and when making When user sucks the aerosol, naringenin can be directly absorbed, and then prevents the inflammation that may cause when smoking, cough, raw phlegm etc. and is anti- It answers.Simultaneously as naringenin is there are certain bacteriostasis, the electronic cigarette liquid with naringenin may also reach up inhibit oral cavity and The effect of bacterium in respiratory tract.
In some embodiments, content of the naringenin in electronic cigarette liquid, with the total weight of the electronic cigarette liquid, Substantially, for example, 0.05%, 0.06%, 0.07%, 0.08%, 0.09%, 0.1%, 0.15%, 0.5%, 1.0%, 1.5%, 5.0%, 10.0%, 15% or these numbers in both any composition range.In some embodiments, the shaddock ped Content of the element in electronic cigarette liquid is calculated as about 0.09% to about 10% with the electronic cigarette liquid gross weight, and the naringenin can make electricity Mouthfeel after sub- tobacco juice atomization is more comfortable, and milder enriches the fragrance of cigarette, improves sucking quality.
Electronic cigarette liquid also includes base solvent, wherein the base solvent includes propylene glycol and glycerine (glycerol).One In a little embodiments, with the total restatement of the electronic cigarette liquid, content of the propylene glycol in electronic cigarette liquid substantially, for example, 15%, 20%, 25%, 30%, 35%, 40%, 50%, 60%, 70% or these weight percent in both any composition range; And content of the glycerine in electronic cigarette liquid is substantially, for example, 30%, 35%, 40%, 45%, 50%, 55%, 60%, 65%, 70% or these weight percent in both any composition range.In some embodiments, the propylene glycol is in electronics Content in tobacco juice is about 20% to about 60%, and content of the glycerine in electronic cigarette liquid is about 40% to about 70%, So that electronic cigarette liquid reaches optimal atomizing effect, user's experience is improved.
It will be understood by those skilled in the art that base solvent can select this field any of molten according to specific requirements Agent, for example, deionized water, propylene glycol, glycerine, and be not limited except as.
In some embodiments, the electronic cigarette liquid further comprises coolant agent, wherein the coolant agent is in electronic cigarette Content in liquid substantially, for example, 0.1%, 0.2%, 0.3%, 0.5%, 1.0%, 1.5%, 2.0%, 2.5%, 5% or this The range of both any composition in a little weight percent.
Coolant agent is additive, for impression and the stimulation that can make product that user be allowed to generate cooling effect when in use The not strong chemicals of property.In some embodiments, the coolant agent includes selected from by menthol, menthones, isomenthone, lactic acid Menthyl ester, WS-23 (N, 2,3- trimethyl -2- butanamide), WS-3 (N- ethyl-is to menthyl -3- formamide), WS-5 (N- (ethoxycarbonylmethyl group)-is to alkane -3- formamide), WS-12 (N- (4- methoxyphenyl)-is to menthyl -3- carboxylic acid amides), second Group composed by sour menthyl ester and combinations thereof.
In some embodiments, the electronic cigarette liquid further comprises flavor components;Wherein the flavor components are selected from The group as composed by ursolic acid, mogroside, synephrine, glycyrrhizin and combinations thereof.
Ursolic acid has clearing lung and relieving cough, and stopping nausea and vomiting by lowering the adverse flow of QI, for treating cough with lung heat, circulation of vital energy in the wrong direction asthma is anxious, and stomach energy is vomitted inverse, dysphoria with smothery sensation mouth It is thirsty and other effects.Mogroside has clearing heat and moistening lung, and relieving sore-throat opens sound, and laxation defaecation is for treating lung-heat type cough, pharyngalgia aphonia, intestines Dry constipation and other effects.Synephrine can promote appetite by wind qi-regulating, warm stomach and accelerate metabolism and a kind of fragrant eliminating phlegm Agent.Glycyrrhizin can be used for treating spleen with , Cheongju thermal detoxification of invigorating the spleen and benefiting qi, expelling phlegm and arresting coughing, relieving spasm to stop pain, the effect of coordinating the drug actions of a prescription Stomach is weak, fatigue and weakness, coughing with a lot of sputum etc..The flavor components that the application electronic cigarette liquid is added by it, can further suppress mouth The reactions such as inflammation, cough and raw phlegm in chamber and respiratory tract simultaneously achieve the effect that antibacterial and cleaning oral cavity when in use.
In some embodiments, content of the flavor components in electronic cigarette liquid, with the total weight of the electronic cigarette liquid Meter, substantially, for example, 0.001%, 0.005%, 0.01%, 0.05%, 0.06%, 0.07%, 0.08%, 0.09%, 0.1%, 0.15%, 0.5%, 1.0%, 1.5%, 5.0%, 10.0%, 15% or these numbers in both any composition model It encloses.In some embodiments, content of the flavor components in the electronic cigarette liquid is calculated as about with the electronic cigarette liquid gross weight 0.001% to about 10%, the flavor components can make electronic cigarette liquid generate the mouthfeel of the aerosol sucked for user more Mellowness, it is finer and smoother, the fragrance of the aerosol is enriched, and then promote user's experience.
In some embodiments, the electronic cigarette liquid further includes nicotine salt.In some embodiments, with the electronic cigarette The total restatement of liquid, content of the nicotine salt in electronic cigarette liquid in the electronic cigarette liquid substantially, for example, 0.001%, 0.01%, 0.1%, 1.0%, 1.5%, 2.0%, 2.5%, 5%, 7.5%, 10% or these weight percent in it is both any The range of composition.In some embodiments, content of the nicotine salt in the electronic cigarette liquid is total with the electronic cigarette liquid Restatement is about 0.001% to about 10.0%.
It should be understood that those skilled in the art can select any of nicotine salt in this field to be added according to actual needs In electronic cigarette liquid, and it is not limited except as.In some embodiments, the nicotine salt includes benzoate.
In some embodiments, the electronic cigarette liquid further includes nicotine.In some embodiments, with the electronic cigarette liquid Total restatement, content of the nicotine in electronic cigarette liquid in the electronic cigarette liquid substantially, for example, 0.001%, 0.01%, 0.1%, 0.2%, 0.5%, 1.0%, 1.5%, 2.0%, 2.5%, 5% or these weight percent in any two The range of person's composition.In some embodiments, content of the nicotine in the electronic cigarette liquid is total with the electronic cigarette liquid Restatement is about 0.001% to about 5.0%.
In some embodiments, above-mentioned electronic cigarette liquid can further include essence.
In some embodiments, the essence include: citronellol, vanillic aldehyde, limonene, Nootkatone, in ethylmaltol At least one.
Citronellol has fresh rose like special aroma, there is bitter taste, its gas generated can be made by being added in electronic cigarette liquid Fragrance in mist is more pure and fresh.Vanillic aldehyde has pure vanilla taste, and fragrance is stable, pure, no impurity taste, is added to electronic cigarette Its aerosol generated can be made purer, fine and smooth in liquid.Limonene has the lemonish fragrance of class, is added to electronic cigarette liquid In its aerosol generated can be made fuller, it is more fragrant and more sweet.Nootkatone has typical citrus and shaddock fragrance, is added to The fragrance in its aerosol generated can be enriched in electronic cigarette liquid, to reduce irritation.Ethylmaltol has caramel odour And fruity, the fragrance that can be improved in its aerosol generated is added in electronic cigarette liquid, while can make the fragrance more It is full.
In some embodiments, content of the essence in electronic cigarette liquid, with the total weight of the electronic cigarette liquid, greatly Cause is, for example, 0.01%, 0.1%, 0.25%, 0.5%, 1.0%, 2.0%, 3.0%, 4.0%, 5.0%, 6.0%, 8.0%, 10% or these numbers in both any composition range.In some embodiments, the essence is in the electronic cigarette Content in liquid is calculated as about 0.5% to about 6% with the electronic cigarette liquid gross weight.
According to some embodiments of the application, the application provides the preparation method of electronic cigarette liquid, and it includes following steps: taking one Quantitative naringenin is dissolved in base solvent, then be added flavor components essence, nicotine salt, then, mix it uniformly with Obtain electronic cigarette liquid.
It will be understood by those skilled in the art that the electronic cigarette liquid of the embodiment of the present application can appoint according to practical preparation demand selection What suitable known method manufacture, and be not limited except as.
According to another level of the application, this application provides a kind of atomising devices, wherein the atomising device includes Electronic cigarette liquid in above-described embodiment.The electronic cigarette liquid can be atomized the gas for generating and sucking for user by the atomising device Mist.
In some embodiments, the atomising device includes electronic cigarette, ultrasonic atomizer or net formula atomizer.
Embodiment
To facilitate a better understanding of the application, it is illustrated by the following examples.These examples belong to the protection of the application Range, but the protection scope of the application is not limited.
Embodiment 1
3 grams of naringenins are added in 47 grams of propylene glycol, 50 grams of glycerine mixing are then added, stirs evenly, obtains electronics Tobacco juice.
Embodiment 2
3 grams of naringenins are added in 47 grams of propylene glycol, 3 grams of ursolic acid are then added and 2 grams of synephrines are uniformly mixed, then plus Enter 45 grams of glycerine mixing, stirs evenly, obtain electronic cigarette liquid.
Embodiment 3
3 grams of naringenins are added in 47 grams of propylene glycol, 1 gram of mogroside is then added and 3 grams of glycyrrhizins are uniformly mixed, 45 grams of glycerine mixing are added, stirs evenly, obtains electronic cigarette liquid.
Embodiment 4
3 grams of naringenins are added in 47 grams of propylene glycol, 2 grams of ursolic acid, 1 gram of mogroside, 1 gram of synephrine are then added And 1 gram of glycyrrhizin is uniformly mixed, and is added 45 grams of glycerine mixing, is stirred evenly, obtain electronic cigarette liquid.
Embodiment 5
3 grams of naringenins are added in 37 grams of propylene glycol, 2 grams of nicotine salts, 2.06 grams of limonenes, 0.34 gram of perfume (or spice) are then added Lan Su, 0.08 gram of ethylmaltol, 0.01 gram of Nootkatone and 55.6 grams of glycerine mixing, stir evenly, obtain electronic cigarette liquid.
Embodiment 6
1 gram of naringenin is added in 43 grams of propylene glycol, 3 grams of ursolic acid are then added and 2 grams of synephrines are uniformly mixed, then plus Enter 3 grams of nicotine salts, 1.43 grams of limonenes, 0.47 gram of vanillic aldehyde, 0.1 gram of ethylmaltol, 0.04 gram of Nootkatone and 46 gram third Triol mixing, stirs evenly, obtains electronic cigarette liquid.
Embodiment 7
2 grams of naringenins are added in 34 grams of propylene glycol, 1 gram of mogroside is then added and 3 grams of glycyrrhizins are uniformly mixed, Add 5 grams of nicotine salts, 2.98 grams of limonenes, 0.45 gram of vanillic aldehyde, 0.15 gram of ethylmaltol, 0.07 gram of Nootkatone and 51.35 grams of glycerine mixing, stir evenly, obtain electronic cigarette liquid.
Embodiment 8
1 gram of naringenin is added in 38 grams of propylene glycol, 2 grams of ursolic acid, 1 gram of mogroside, 1 gram of synephrine are then added And 1 gram of glycyrrhizin is uniformly mixed, add 5 grams of nicotine salts, 1.63 grams of limonenes, 0.43 gram of vanillic aldehyde, 0.01 gram of citronellol, 0.11 gram of ethylmaltol, 0.02 gram of Nootkatone and 48.8 grams of glycerine mixing, stir evenly, obtain electronic cigarette liquid.
Then by the aerosol progress naringenin content measurement after the electronic cigarette liquid of embodiment 1 and its atomization and to embodiment 1- 8 electronic cigarette liquid carries out Bacteria suppression test and mouth feel score test.To further illustrate, the application electronic cigarette liquid was being used The content of naringenin, fungistatic effect and its promotion to user's experience in Cheng Zhongqi aerosol.
Naringenin content measuring mode;
Sample preparation: the electronic cigarette liquid of embodiment 1 is generated it using following Smoking regime and is used for user's sucking Aerosol: atomising device is electronic cigarette, suction time be between ± 0.1 second 3.0 seconds, suction between be divided into ± 0.5 second 30.0 seconds, suction Number is 50 times, each aspiration is 55mL ± 0.3mL.Aerosol is collected using cambridge filter, and submerges sword using 10mL methanol Bridge filter disc, after ultrasonic extraction 30min flue gas extraction solution.
Liquid chromatogram test: ultra performance liquid chromatography (UPLC) (model: Waters ACQUITY is usedHSS T3 C18Chromatographic column (2.1mm × 100mm, 1.7 μm)) naringenin content measurement is carried out to electronic cigarette liquid and its aerosol extraction solution, Wherein liquid phase chromatogram condition is as follows: mobile phase is -0.1% formic acid solution of acetonitrile (30:70, v/v), and isocratic elution, flow is 0.3mL/min, 35 DEG C of column temperature, sample volume 5 μ L, Detection wavelength 276nm.
Figure 1A and 1B is passing through according to the electronic cigarette liquid of the embodiment of the present application and its aerosol generated respectively The chromatogram of shaddock ped cellulose content measured by UPLC.
As illustrated by figures 1 a and 1b, there are naringenins in the aerosol of the application electronic cigarette liquid, wherein in aerosol naringenin at Divide essentially identical with the ingredient in electronic cigarette liquid.Therefore, naringenin can be effectively by human body by the aerosol after electronic cigarette atomizing Absorb, and then reach anti-inflammatory, cough-relieving, resolving sputum and inhibition bacterium and other effects.
Bacteria suppression test mode;
Sample preparation: CORESTA (Cooperation Centre for Scientific Research is used Relative to Tobacco) standard (test document: ISO 20768:2018) by atomising device (electronic cigarette) by sample mist Metaplasia collects aerosol at aerosol, and using cambridge filter, and absorption aerosol weight is 0.716g.Then cambridge filter is put into small In beaker, 50% ethyl alcohol of 7.16mL is then added, using ultrasonic extraction 30mins, it is molten to be made into the extraction that concentration is 100mg/mL Liquid.Extraction solution is diluted to obtain into graded series concentration (50,25,12.5,6.25,3.125,1.562,0.781mg/mL) Test solution.
The preparation of bacteria suspension: the strain of preservation: Streptococcus mutans (ATCC 25175) and tooth is taken out from -80 DEG C of environment Gum Detection of Porphyromonas (ATCC 33277), therefrom the appropriate bacterium colony of picking is placed on plate, and 36h activation is cultivated at 37 DEG C.With After pick from the plate appropriate bacterium colony and be placed in another plate, 36h is cultivated at 37 DEG C, and repeat the step 2 time.
With oese picking proper amount of strains in centrifuge tube, shake well is diluted to obtain 105 to 106CFU/mL bacterium Suspension.
Preparation with medicine plate: taking the test solution 1mL of various concentration, is added in culture dish, then be added in culture dish The culture medium of 9mL, shakes up.Be configured to graded series concentration (10,5,2.5,1.25,0.625,0.3125,0.1562, Drug plates 0.0781mg/mL), sample solvent are negative control, and culture dish is horizontally arranged after being finished down, solidifies culture medium, It is spare.
Bacteria suppression measurement: 100 μ L bacteria suspensions are taken to be added in uniformly spreadable on band medicine plate.Culture is inverted for 24 hours in 37 DEG C, Observation is for trying bacterium growing state, and the minimum sample concentration for recording complete inhibition bacterial growth is to inhibit dense to the minimum for trying bacterium It spends (Minimum Inhibitory Concentration, MIC).
Test result is as follows shown in table 1 by Bacteria suppression test for the electronic cigarette liquid of embodiment 1-8.
Table 1
By data in table 1 it is found that the electronic cigarette liquid of the embodiment of the present application 1-8 can effectively inhibit the growth of bacterium, to reach To the effects of cleaning oral cavity, pre- anti-caries.
Mouth feel score test mode;
Statistical method: ask each evaluation index in 20 evaluation and analysis person accordings to the form below 2 to the electronic cigarette liquid of above-described embodiment 1-8 Aerosol experience marking generated.
Table 2
Test result is as follows shown in table 3 by mouth feel score test for the electronic cigarette liquid of embodiment 1-8.
Table 3
From the data in table 3, the electronic cigarette liquid of the embodiment of the present application 1-8 is formed by after being atomized sucks for user Aerosol, experienced no matter all showing it in mouthfeel or taste with good user.In addition, by comparing embodiment It is found that adding flavor component in electronic cigarette liquid, the taste and mouthfeel of electronic cigarette liquid aerosol generated can be further promoted.
It, should by the above embodiments of the present application it should be appreciated that this application provides a kind of electronic cigarette liquid containing naringenin The naringenin that certain content is able to maintain in the aerosol for user's sucking is generated in electronic cigarette liquid by atomising device, into And it is absorbed by the body and plays the health-care effect of anti-inflammatory, cough-relieving apophlegmatic, while electronic cigarette liquid further has fungistatic effect.This Shen Please electronic cigarette liquid can be atomized by atomising device, and be atomized after mouthfeel it is more comfortable, milder enriches the fragrance of cigarette, mentions Sucking quality is risen
Although the specific embodiment for having referred to the application describes and illustrates that the application, these descriptions and instructions are simultaneously unlimited The application processed.Those skilled in the art can be clearly understood from, and not depart from this Shen as defined by the appended patent claims In the case where true spirit please and range, various changes can be carried out, so that particular condition, material, material composition, substance, side Method or process are suitable for an object of the application, spirit and scope.All such modifications are intended in this appended claims In range.Although having referred to the specific operation being performed in a specific order describes method disclosed herein, it should be appreciated that can be These operations are combined, segment or resequenced in the case where the teaching for not departing from the application to form equivalent method.Therefore, unless Special instructions herein, the order and grouping otherwise operated and not this Applicant's Abstract graph limitation.
Feature in terms of several embodiments and details of foregoing general description the application.Embodiment described in this application can be easy Ground is used as designing or modifying the basis of other processes and for executing same or similar purpose and/or being incorporated herein In embodiment same or similar advantage structure.Such equivalent constructions without departing from spirit and scope, and It can be variously modified, substitute and change in the case where not departing from spirit and scope.

Claims (10)

1. a kind of electronic cigarette liquid, it includes naringenins, wherein content of the naringenin in the electronic cigarette liquid is with the electricity Sub- tobacco juice gross weight is calculated as 0.09% to 10%.
2. electronic cigarette liquid according to claim 1 further includes nicotine salt, and the nicotine salt is in the electricity Content in sub- tobacco juice is calculated as 0.001% to 10% with the electronic cigarette liquid gross weight.
3. electronic cigarette liquid according to claim 1 further includes nicotine, and the nicotine is in the electronic cigarette Content in liquid is calculated as 0.001% to 5% with the electronic cigarette liquid gross weight.
4. further including essence to electronic cigarette liquid described in any claim in 3 according to claim 1.
5. electronic cigarette liquid according to claim 4, wherein including: citronellol, vanillic aldehyde, limonene, circle in the essence At least one of shaddock ketone, ethylmaltol.
6. electronic cigarette liquid according to claim 5, wherein content of the essence in the electronic cigarette liquid is with the electricity Sub- tobacco juice gross weight is calculated as 0.5% to 6%.
7. further including flavor components to electronic cigarette liquid described in any claim in 3 according to claim 1;Wherein The flavor components are selected from the group as composed by ursolic acid, mogroside, synephrine, glycyrrhizin and combinations thereof.
8. electronic cigarette liquid according to claim 7, wherein content of the flavor components in the electronic cigarette liquid is with institute It states electronic cigarette liquid gross weight and is calculated as 0.001% to 10%.
9. a kind of atomising device, it includes electronic cigarette liquids described in any claim in claim 1 to 8.
10. atomising device according to claim 9, wherein the atomising device includes electronic cigarette, ultrasonic atomizer or net Formula atomizer.
CN201910816296.7A 2019-08-30 2019-08-30 Electronic cigarette liquid Pending CN110353298A (en)

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PCT/CN2019/127156 WO2021036121A1 (en) 2019-08-30 2019-12-20 E-liquid

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Cited By (7)

* Cited by examiner, † Cited by third party
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WO2021036121A1 (en) * 2019-08-30 2021-03-04 深圳雾芯科技有限公司 E-liquid
WO2021102653A1 (en) * 2019-11-25 2021-06-03 深圳雾芯科技有限公司 E-liquid
WO2021102652A1 (en) * 2019-11-25 2021-06-03 深圳雾芯科技有限公司 E-liquid
CN113261704A (en) * 2021-06-03 2021-08-17 上海净颖环保科技股份有限公司 Novel electronic cigarette and electronic cigarette liquid thereof
EP3888662A1 (en) * 2020-04-02 2021-10-06 Vossensteyn Compounds, compositions and devices for use in the treatment of coronavirus infections
CN113679085A (en) * 2021-08-20 2021-11-23 山东沛学生物工程有限公司 Electronic atomized tobacco liquid and preparation method thereof
CN114858939A (en) * 2022-04-27 2022-08-05 国家烟草质量监督检验中心 Method for simultaneously determining eugenol, maltol, ethyl maltol, vanillin and ethyl vanillin in novel atomized product

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH09121829A (en) * 1995-11-08 1997-05-13 Japan Tobacco Inc Improver for fragrance inhaling taste of tobacco
CN104284606A (en) * 2012-01-31 2015-01-14 奥驰亚客户服务公司 Electronic cigarette
CN104817602A (en) * 2015-04-02 2015-08-05 湖南中烟工业有限责任公司 Extraction method and use method of naringin
CN103622154B (en) * 2013-12-17 2015-09-09 郑悦 Electronic cigarette liquid and preparation method thereof
CN105154227A (en) * 2015-06-17 2015-12-16 湖北中烟工业有限责任公司 Plant flavone essence cigarette bead for cigarette, and preparation method and application thereof
CN105029689B (en) * 2015-06-17 2017-03-29 湖北中烟工业有限责任公司 Cigarette flavone compound essence cigarette pearl, preparation method and application
CN109805440A (en) * 2019-02-21 2019-05-28 吉林烟草工业有限责任公司 A kind of tobacco fixation humectant and preparation method thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103284317A (en) * 2012-03-01 2013-09-11 李桂雨 Low-tar Chinese herbal medicine cigarette
CN104605484A (en) * 2015-03-03 2015-05-13 华健 Organic tobacco tar capable of relieving cough and reducing sputum and preparation method for organic tobacco tar
CN110353298A (en) * 2019-08-30 2019-10-22 深圳雾芯科技有限公司 Electronic cigarette liquid

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH09121829A (en) * 1995-11-08 1997-05-13 Japan Tobacco Inc Improver for fragrance inhaling taste of tobacco
CN104284606A (en) * 2012-01-31 2015-01-14 奥驰亚客户服务公司 Electronic cigarette
CN103622154B (en) * 2013-12-17 2015-09-09 郑悦 Electronic cigarette liquid and preparation method thereof
CN104817602A (en) * 2015-04-02 2015-08-05 湖南中烟工业有限责任公司 Extraction method and use method of naringin
CN107536102A (en) * 2015-04-02 2018-01-05 湖南中烟工业有限责任公司 A kind of application process of aurantiin
CN105154227A (en) * 2015-06-17 2015-12-16 湖北中烟工业有限责任公司 Plant flavone essence cigarette bead for cigarette, and preparation method and application thereof
CN105029689B (en) * 2015-06-17 2017-03-29 湖北中烟工业有限责任公司 Cigarette flavone compound essence cigarette pearl, preparation method and application
CN109805440A (en) * 2019-02-21 2019-05-28 吉林烟草工业有限责任公司 A kind of tobacco fixation humectant and preparation method thereof

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
无锡轻工业学院合编: "《食品生物化学》", 31 August 2007, 中国轻工业出版社 *
李建颖等: "《食品添加剂速查手册》", 30 November 2017, 南开大学出版社 *
江苏省糖业食品科技情报站编著: "《新糖源及其应用》", 31 August 1997, 轻工业出版社 *

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2021036121A1 (en) * 2019-08-30 2021-03-04 深圳雾芯科技有限公司 E-liquid
WO2021102653A1 (en) * 2019-11-25 2021-06-03 深圳雾芯科技有限公司 E-liquid
WO2021102652A1 (en) * 2019-11-25 2021-06-03 深圳雾芯科技有限公司 E-liquid
EP3888662A1 (en) * 2020-04-02 2021-10-06 Vossensteyn Compounds, compositions and devices for use in the treatment of coronavirus infections
WO2021198316A1 (en) * 2020-04-02 2021-10-07 Vossensteyn Compounds, compositions and devices for use in the prevention or treatment of corona-virus infections
CN113261704A (en) * 2021-06-03 2021-08-17 上海净颖环保科技股份有限公司 Novel electronic cigarette and electronic cigarette liquid thereof
CN113261704B (en) * 2021-06-03 2022-11-08 上海净颖环保科技股份有限公司 Electronic cigarette and electronic cigarette liquid thereof
CN113679085A (en) * 2021-08-20 2021-11-23 山东沛学生物工程有限公司 Electronic atomized tobacco liquid and preparation method thereof
CN113679085B (en) * 2021-08-20 2023-06-02 山东沛学生物工程有限公司 Electronic atomization tobacco juice and preparation method thereof
CN114858939A (en) * 2022-04-27 2022-08-05 国家烟草质量监督检验中心 Method for simultaneously determining eugenol, maltol, ethyl maltol, vanillin and ethyl vanillin in novel atomized product

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