CN110170343A - A kind of Water-In-Oil microlayer model manufacture system and manufacturing method - Google Patents
A kind of Water-In-Oil microlayer model manufacture system and manufacturing method Download PDFInfo
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- CN110170343A CN110170343A CN201910447194.2A CN201910447194A CN110170343A CN 110170343 A CN110170343 A CN 110170343A CN 201910447194 A CN201910447194 A CN 201910447194A CN 110170343 A CN110170343 A CN 110170343A
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
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Abstract
The present invention provides a kind of Water-In-Oil microlayer model manufacture system and manufacturing method, including sample storage container, for storing the fluid sample for manufacturing microlayer model, and for storing the oil reservoir for being located at the fluid sample upper surface；The sample storage upper vessel portion opening setting；Fluid column generation device is connect with the sample storage container, for pushing up the fluid sample stored in the sample storage container so that forming a fluid column on the interface that fluid sample connects with oil reservoir；And when the fluid column generation device is closed, and the fluid column is fallen after rise, the surface tension at interface is by the fluid column pinch off and forms on the interface Water-In-Oil microlayer model.By upper, the application will not influence the activity of biological sample in microlayer model when manufacturing microlayer model, and be not in the problem of device blocks, and be not easy to be lost, and at low cost.
Description
Technical field
The present invention relates to technical field of micro-nano manufacture more particularly to a kind of Water-In-Oil microlayer model manufacture system and manufacturers
Method.
Background technique
Due to microlayer model have the advantages that small in size, stable reaction conditions, can avoid sample room cross contamination, by with
Numerous reactions and process under the fields such as chemistry and life science.Such as: chemical analysis and synthesis, protein crystal, cell packet
It buries, drop PCR etc..The key of microlayer model manufacture is: 1) homogeneity of microlayer model；2) pattern of microlayer model is (generally regular
Circle)；3) size of microlayer model.Microlayer model manufacturing technology traditional at present has the drawback that 1) cost is high；2) biology is simultaneous
Capacitive is poor；3) sample solution is consumed big；Etc..The shortcomings that for another example using nozzle to generate microlayer model in the prior art is as follows: 1)
Nozzle is easy blocking in use.2) it is difficult to clean after nozzle use, residue can draw when experiment next time
Play cross contamination.3) material of nozzle is generally metal, but metal easily interacts with certain materials (such as protein) and influenced
The bioactivity of albumen.4) nozzle is needed replacing in order to generate various sizes of drop, and it is relatively high to manufacture micro-nozzle price.
Therefore, a kind of microlayer model manufacture system is needed at present, and to realize when manufacturing microlayer model, it is living not influence sample biology
Property, do not occur the problem of instrument blocking, be not easy to be lost, and is at low cost.
Summary of the invention
In view of this, the main purpose of the present invention is to provide a kind of microlayer model manufacture system, it is micro- in manufacture to realize
When drop, sample bioactivity is not influenced, does not occur the problem of instrument blocking, is not easy to be lost, and at low cost.
The application provides a kind of microlayer model manufacture system, comprising:
Sample storage container is located at the liquid for storing the fluid sample for manufacturing microlayer model, and for storing
The oil reservoir of body sample upper surface；The sample storage upper vessel portion opening setting；
Fluid column generation device is connect with the sample storage container bottom, for will store in the sample storage container
Fluid sample push up so that forming a fluid column on the interface that fluid sample connects with oil reservoir；And when the fluid column produces
Generating apparatus is closed, and when the fluid column is fallen after rise, formation oil wraps the surface tension at interface by the fluid column pinch off and on the interface
Water microlayer model.
By upper, the microlayer model manufacture system of the application forms liquid at fluid sample-oil reservoir interface by fluid column generation device
Column is then shut off device, is freely fallen after rise final pinch off fluid column by surface tension by fluid column and forms drop.Without
Nozzle, therefore the problem that the person's of avoiding nozzle tape comes.The application is realized when manufacturing microlayer model, no by above-mentioned technical characteristic
Sample bioactivity is influenced, does not occur the problem of instrument blocking, is not easy to be lost, it is high-efficient and at low cost.Wherein, in the application
Oil reservoir can be used other and fluid sample and be not desired to the liquid dissolved and density ratio fluid sample is small, all to belong to by generating liquid
Then column falls the technical solution of generation drop after rise all within the scope of protection of this application.
Preferably, the fluid column generation device, comprising:
Thin film bulk acoustic wave resonator is set to the bottom in the sample storage container；Wherein, the film bulk acoustic is humorous
The quantity of vibration device is at least 1；Wherein, the thin film bulk acoustic wave resonator is arranged in the form of an array or with other specified arrangement shape
Formula setting.
Signal generator is connect with the thin film bulk acoustic wave resonator.
By upper, high-frequency signal is generated by the signal generator, drives the thin film bulk acoustic wave resonator resonance in turn
High frequency sound wave is generated, which upwardly propagates in the fluid sample in the sample storage container, generates powerful body
Product is pushed hydrodynamic body and is moved upwards.To form a fluid column on fluid sample-oil reservoir surface.Skill of the application as a result,
The problems such as art feature avoids the device of the prior art from blocking, is easily lost, low efficiency, the high bio-compatibility of cost is poor.The thin-film body
Acoustic resonator is also possible to some other acoustic wave devices that can produce fluid column.Wherein, when the film bulk acoustic resonator
When device is arranged in the form of an array or specifies arrangement form to be arranged with other, the size of the Water-In-Oil microlayer model of generation is uniform and shape
Looks rule.
Preferably, a power amplifier is also connected between the signal generator and the thin film bulk acoustic wave resonator；Its
In, the power amplifier is input to the film bulk acoustic after the signal amplification for issuing the signal generator
Resonator.
By upper, signal can be amplified to required specified power by power amplifier, for driving the film
Bulk acoustic wave resonator resonance generates high frequency sound wave in turn.
Preferably, the system, further includes: central processing unit is connect, for controlling signal with the signal generator
Transmitting；It controls to control working time and the power of thin film bulk acoustic wave resonator by the signal and generates the micro- liquid of Water-In-Oil
The size of drop.
Preferably, the system, further includes: high-speed camera is connect with the central processing unit, is set to the sample
The side of storage container for acquiring the whole process of microlayer model formation in real time, and transmits it to central processing unit；Wherein,
The side wall of the sample memory is transparent material.
The application also provides a kind of microlayer model manufacturing method, comprising steps of
A, fluid sample and oil sample are implanted sequentially into sample storage container so that in the sample storage container by
Under supreme sequentially form fluid sample layer and oil reservoir；
B, the fluid sample stored in the sample storage container is pushed up so that liquid by fluid column generation device
A fluid column is formed on the interface that body sample connects with oil reservoir；
C, the fluid column generation device is closed, the fluid column is fallen after rise, and the surface tension at the interface is by the fluid column pinch off
And Water-In-Oil microlayer model is formed on the interface.
By upper, the microlayer model manufacture system of the application does not need nozzle, therefore avoids the problem of nozzle tape.Such as nozzle
The problems such as cost height and easily blocking.The application is realized by above-mentioned technical characteristic when manufacturing microlayer model, and it is raw not influence sample
Object activity, does not occur the problem of instrument blocking, is not easy to be lost, high-efficient and at low cost.
Preferably, the fluid column generation device includes:
Thin film bulk acoustic wave resonator is set to the bottom in the sample storage container；
Signal generator is connect with the thin film bulk acoustic wave resonator；
Wherein, a power amplifier is also connected between the signal generator and the thin film bulk acoustic wave resonator；Wherein,
The power amplifier is input to the film bulk acoustic resonator after the signal amplification for issuing the signal generator
Device.
By upper, high-frequency signal is generated by the signal generator, the film is driven after power amplifier amplifies
Bulk acoustic wave resonator resonance generates high frequency sound wave in turn, the high frequency sound wave in the fluid sample in the sample storage container to
Upper propagation generates powerful body force and liquid is pushed to move upwards.To form a liquid on fluid sample-oil reservoir surface
Column.The technical characteristic of the application avoids the device of the prior art from blocking, is easily lost, low efficiency, the high bio-compatible of cost as a result,
The problems such as property is poor.The thin film bulk acoustic wave resonator is also possible to some other acoustic wave devices that can produce fluid column.
Preferably, the step B, comprising:
B1, the signal generator generation high-frequency signal is controlled by a central processing unit；
Driving thin film bulk acoustic wave resonator resonance generates height in turn after B2, the high-frequency signal amplify via power amplifier
Frequency sound wave；The high frequency sound wave acts on the fluid sample in the storage container, generate powerful body force push liquid to
Upper movement forms a fluid column.
Preferably, the step C, comprising:
The power amplifier is closed to stop the output of the signal of the signal generator, so that the film bulk acoustic
Resonator stops generating high frequency sound wave so that the fluid column is fallen after rise, the surface tension at the interface by the fluid column pinch off and
Water-In-Oil microlayer model is formed on the interface.
Preferably, the step A, further includes:
Time and the power that the signal generator generates high-frequency signal are controlled by the central processing unit, to pass through
The working time of the signal control thin film bulk acoustic wave resonator and power, to pass through the work of the thin film bulk acoustic wave resonator
The generation time of fluid column described in time and power control and the size of the control fluid column, to control the micro- liquid of the Water-In-Oil
The size of drop.
Preferably, the step B, comprising:
B1, the signal generator generation high-frequency signal is controlled by a central processing unit；
Driving thin film bulk acoustic wave resonator resonance generates height in turn after B2, the high-frequency signal amplify via power amplifier
Frequency sound wave；The high frequency sound wave acts on the fluid sample in the storage container, generate powerful body force push liquid to
Upper movement forms a fluid column.
Preferably, the step C, comprising:
The power amplifier is closed to stop the output of the signal of the signal generator, so that the film bulk acoustic
Resonator stops generating high frequency sound wave so that the fluid column is fallen after rise, the surface tension at the interface by the fluid column pinch off and
Water-In-Oil microlayer model is formed on the interface.
Preferably, the step A, further includes:
Time and the power that the signal generator generates high-frequency signal are controlled by the central processing unit, to pass through
The working time of the signal control thin film bulk acoustic wave resonator and power, to pass through the work of the thin film bulk acoustic wave resonator
The generation time of fluid column described in time and power control and the size of the control fluid column, to control the micro- liquid of the Water-In-Oil
The size of drop.
In conclusion the microlayer model manufacture system of the application is by fluid column generation device in fluid sample-oil reservoir interface shape
At fluid column, it is then shut off device, final pinch off fluid column is freely fallen after rise by surface tension by fluid column and forms drop.The present invention
Microlayer model manufacture system do not need nozzle, therefore avoid the problem of nozzle tape.As in the prior art: nozzle cost it is high and
The problems such as easily blocking.The application is realized by above-mentioned technical characteristic when manufacturing microlayer model, does not influence sample bioactivity, no
There is the problem of instrument blocking, is not easy to be lost, it is high-efficient and at low cost.And the application can control institute by central processing unit
Time and power that signal generator generates high-frequency signal are stated, to control the work of thin film bulk acoustic wave resonator by the signal
Make time and power, to pass through the generation time of fluid column described in the working time of the thin film bulk acoustic wave resonator and power control
And the height and diameter of the control fluid column, to control the size of the Water-In-Oil microlayer model.Wherein, the oil in the application
Layer can be used other and fluid sample and be not desired to the liquid dissolved and density ratio fluid sample is small, all to belong to by generating fluid column
Then the technical solution of generation drop is fallen after rise all within the scope of protection of this application.
Detailed description of the invention
Fig. 1 is the structural schematic diagram of the Water-In-Oil microlayer model manufacture system of the application；
Fig. 2 is the flow diagram of the Water-In-Oil microlayer model manufacturing method of the application；
Shown in Fig. 3, it is expressed as the relationship of the size of the working time of thin film bulk acoustic wave resonator 105 and the microlayer model of generation
Figure；
Shown in Fig. 4, it is expressed as the relational graph of the size of the power of thin film bulk acoustic wave resonator 105 and the microlayer model of generation.
Specific embodiment
This application provides a kind of Water-In-Oil microlayer model manufacture system and method, to realize when manufacturing microlayer model, not shadow
Sample bioactivity is rung, and is not in the problem of instrument blocks, is not easy to be lost, it is high-efficient.Specifically, as follows:
Embodiment one
As shown in Figure 1, a kind of Water-In-Oil microlayer model manufacture system provided by the present application, comprising:
Sample storage container 101, for storing the fluid sample for manufacturing microlayer model, and for store be located at it is described
The oil reservoir 102 (such as mineral oil) of fluid sample 103 (such as deionized water) upper surface；Wherein, the body of fluid sample and oil reservoir
Product ratio is less than 1, that is, the volume of oil reservoir wants larger；Wherein it is preferred to fluid sample: the volume ratio of oil reservoir is 1:4.The sample
The setting of 101 upper opening of product storage container；Using EVB plate as substrate 106, the sample storage is held for the bottom of sample storage container
The side wall of device is transparent material, for example, transparent material can be PMMA organic glass, is also possible to other transparent materials.
Fluid column generation device is connect with 100 bottom substrate 106 of sample storage container, is used for the sample storage
The fluid sample 103 stored in container 101 pushes up so that being formed on the interface that fluid sample 103 connects with oil reservoir 102
One fluid column；And when the fluid column generation device is closed, and the fluid column is fallen after rise, the surface tension at interface is by the fluid column pinch off
And Water-In-Oil microlayer model is formed on the interface.
Wherein, the fluid column generation device, comprising:
Thin film bulk acoustic wave resonator 105 is set to the bottom in the sample storage container；Wherein, the thin-film body sound
The quantity of wave resonator 105 is at least 1；Wherein, the thin film bulk acoustic wave resonator 105 is arranged in the form of an array or with other
Specified arrangement form setting.Wherein, the thin film bulk acoustic wave resonator 105 is the microelectromechanical systems using standard
(MEMS) technique produces thin film bulk acoustic wave resonator, and high production efficiency is at low cost, and is very easy to integrated.And it connects
To act on the fluid sample in the substrate of sample storage container bottom.The thin film bulk acoustic wave resonator 105 is also possible to
Some other acoustic wave devices that can produce fluid column.
Signal generator 110 is connect with the thin film bulk acoustic wave resonator 105.
Wherein, a power amplifier is also connected between the signal generator 110 and the thin film bulk acoustic wave resonator 105
109；Wherein, the power amplifier is input to the film after the signal amplification for issuing the signal generator
Bulk acoustic wave resonator.
High-frequency signal is generated by the signal generator 110, drives the film after the amplification of power amplifier 109
105 resonance of bulk acoustic wave resonator and then generation high frequency sound wave 104, liquid-like of the high frequency sound wave in the sample storage container
Upwardly propagated in product, the high frequency sound wave rapid decay being coupled in fluid sample, generate powerful body force push liquid to
Upper movement.To form a fluid column on fluid sample-oil reservoir surface.Later by computer shutdown signal generator to make
Thin film bulk acoustic wave resonator stops working.Since fluid column loses the promotion of body force at this time, surface tension falls fluid column after rise.By
In Rayleigh-Plateau unstability, (Plateau-Rayleigh instability is in description water column flow process
Disturbing phenomenon, Plateau first measure it, and then Rayleig proposes that mathematical model explains), surface tension will
Fluid column pinch off simultaneously forms Water-In-Oil drop, rests on fluid sample-oil reservoir interface.
Wherein, the system, further includes: central processing unit 108 is connect with the signal generator 110, for controlling letter
Number transmitting；It controls to control working time and the power of thin film bulk acoustic wave resonator 105 by the signal and generates oil
The size of packet water microlayer model, being realized at a few micrometers to the size for freely controlling drop between hundreds of microns.Specifically, as schemed
Shown in 3, it is expressed as the relational graph of the size of the working time of thin film bulk acoustic wave resonator 105 and the microlayer model of generation；Such as Fig. 3 institute
Show, (must ask can be herein for power and any one between 400mw to 2w can generate micro- liquid under the premise of power stability
The power of drop), with the increase of working time, the size presentation of microlayer model first increases the trend to tend towards stability afterwards, such as Fig. 3 institute
Show, before 1.5 seconds, with the increase of working time, the size of microlayer model is gradually increased.After 1.5 seconds, with the working time
Increase, the size of microlayer model tends towards stability.As shown in figure 4, be expressed as thin film bulk acoustic wave resonator 105 power and generation it is micro-
The relational graph of the size of drop.After 1.5 seconds (time no longer has an impact the size of microlayer model after 1.5 seconds), later
The size of the microlayer model of generation can be adjusted by adjusting power, as shown in figure 4, with the increase of power, the ruler of microlayer model
It is very little to be gradually increased.
Wherein, the system, further includes: high-speed camera 107 is connect with the central processing unit 108, is set to described
The side of sample storage container, the whole process formed for acquiring the Water-In-Oil microlayer model in real time；Wherein, the sample is deposited
The side wall of reservoir is transparent material.
For the clearer technical solution for illustrating the application, now by the work of the Water-In-Oil microlayer model manufacture system of the application
It is described as follows as principle:
GHz grades of high-frequency signal is generated via power amplifier by 108 control signal generator 110 of central processing unit
Driving 105 resonance of thin film bulk acoustic wave resonator generates high frequency sound wave in turn after 109 amplifications.It is coupled in fluid sample 103
104 rapid decay of high frequency sound wave, and generate powerful body force promotion and fluid sample 103 is gone to move upwards.In fluid sample
102 interface of 103- oil reservoir, the surface tension upward movement of liquid (meeting the law of conservation of momentum).To be formed in water-oil interface
One fluid column.Later by computer shutdown signal generator 110 to make thin film bulk acoustic wave resonator 105 stop working.By
The promotion of body force is lost in fluid column at this time, surface tension falls fluid column after rise.Due to Rayleigh-Plateau unstability,
Surface tension is by fluid column pinch off and forms Water-In-Oil drop, rests on 102 interface of fluid sample 103- oil reservoir.Pass through central processing
Device 108 controls high-speed camera 107 can observe entire with forming drop process in real time.
Embodiment two
A kind of Water-In-Oil microlayer model manufacture system is also provided based on the application in embodiment one, the application also provides one kind
Microlayer model manufacturing method, comprising steps of
Fluid sample and oil sample are implanted sequentially into sample storage container by S201, so that the sample storage container
In sequentially form fluid sample layer and oil reservoir from the bottom to top.
S202 generates high-frequency signal by a central processing unit control signal generator.And pass through central processing unit control
The time for the high-frequency signal that signal generator processed generates and power.
S203, driving thin film bulk acoustic wave resonator resonance generates high frequency in turn after high-frequency signal amplifies via power amplifier
Sound wave；The high frequency sound wave acts on the fluid sample in the storage container, generates powerful body force and pushes liquid upward
Movement, so that forming a fluid column on the interface that fluid sample connects with oil reservoir.
S204 stops the signal output of the signal generator, so that the thin film bulk acoustic wave resonator stops generating
High frequency sound wave, so that the fluid column is fallen after rise, the surface tension at the interface is formed the fluid column pinch off and on the interface
Water-In-Oil microlayer model.
Wherein, time and the power that the signal generator generates high-frequency signal are controlled by the central processing unit,
To control working time and the power of thin film bulk acoustic wave resonator by the signal, to pass through the film bulk acoustic resonator
The generation time of fluid column described in the working time of device and power control and the size of the control fluid column, to control the oil
The size of packet water microlayer model.
Thin film bulk acoustic wave resonator is set to the bottom in the sample storage container；
Signal generator is connect with the thin film bulk acoustic wave resonator；
Wherein, a power amplifier is also connected between the signal generator and the thin film bulk acoustic wave resonator；Wherein,
The power amplifier is input to the film bulk acoustic resonator after the signal amplification for issuing the signal generator
Device.
In conclusion the Water-In-Oil microlayer model manufacture system and method for the application pass through in fluid sample-oil reservoir interface shape
At fluid column, it is then shut off device, final pinch off fluid column is freely fallen after rise by surface tension by fluid column and forms drop.This hair
Avoid the problem of nozzle tape.The application is realized by above-mentioned technical characteristic when manufacturing microlayer model, and it is raw not influence sample
Object activity, does not occur the problem of instrument blocking, is not easy to be lost, high-efficient and at low cost.And the application can pass through centre
Reason device controls time and the power that the signal generator generates high-frequency signal, to control film bulk acoustic by the signal
The working time of resonator and power, to pass through fluid column described in the working time of the thin film bulk acoustic wave resonator and power control
Generation time and the control fluid column height and diameter, to control the size of the Water-In-Oil microlayer model.Wherein, originally
Oil reservoir in application can be used it is other be not desired to dissolution and the small liquid of density ratio fluid sample with fluid sample, it is all belong to it is logical
It crosses and generates fluid column and then fall the technical solution of generation drop after rise all within the scope of protection of this application.
The foregoing is merely illustrative of the preferred embodiments of the present invention, is not intended to limit the invention, all in essence of the invention
Within mind and principle, any modification, equivalent replacement, improvement and so on be should all be included in the protection scope of the present invention.
Claims (10)
1. a kind of Water-In-Oil microlayer model manufacture system characterized by comprising
Sample storage container is located at the liquid-like for storing the fluid sample for manufacturing microlayer model, and for storing
The oil reservoir of product upper surface；The sample storage upper vessel portion opening setting；
Fluid column generation device is connect with the sample storage container bottom, the liquid for will store in the sample storage container
Body sample pushes up so that forming a fluid column on the interface that fluid sample connects with oil reservoir；And when the fluid column generates dress
Set closing, the fluid column is fallen after rise, and the surface tension at interface is by the fluid column pinch off and forms on the interface the micro- liquid of Water-In-Oil
Drop.
2. system according to claim 1, which is characterized in that the fluid column generation device, comprising:
Thin film bulk acoustic wave resonator is set to the bottom in the sample storage container；Wherein, the thin film bulk acoustic wave resonator
Quantity be at least 1；Wherein, the arrangement shape that the thin film bulk acoustic wave resonator is arranged in the form of an array or is specified with others
Formula setting；
Signal generator is connect with the thin film bulk acoustic wave resonator.
3. system according to claim 2, which is characterized in that the signal generator and the thin film bulk acoustic wave resonator
Between be also connected with a power amplifier；Wherein, the power amplifier, the signal amplification for issuing the signal generator
It is input to the thin film bulk acoustic wave resonator later.
4. system according to claim 2, which is characterized in that further include:
Central processing unit is connect with the signal generator, for controlling the transmitting of signal；With thin to control by the signal
The working time of membrane body acoustic resonator and power are to control the size for generating Water-In-Oil microlayer model.
5. according to system described in claim 2-4, which is characterized in that further include:
High-speed camera is connect with the central processing unit, is set to the side of the sample storage container, for acquiring in real time
The whole process that microlayer model is formed, and transmit it to central processing unit；Wherein, the side wall of the sample memory is transparent material
Matter.
6. a kind of Water-In-Oil microlayer model manufacturing method, which is characterized in that comprising steps of
A, fluid sample and oil sample are implanted sequentially into sample storage container so that in the sample storage container by down toward
On sequentially form fluid sample layer and oil reservoir；
B, the fluid sample stored in the sample storage container is pushed up so that liquid-like by fluid column generation device
A fluid column is formed on the interface that product connect with oil reservoir；
C, close the fluid column generation device, the fluid column is fallen after rise, the surface tension at the interface by the fluid column pinch off and
Water-In-Oil microlayer model is formed on the interface.
7. according to the method described in claim 6, it is characterized in that, the fluid column generation device includes:
Thin film bulk acoustic wave resonator is set to the bottom in the sample storage container；
Signal generator is connect with the thin film bulk acoustic wave resonator；
Wherein, a power amplifier is also connected between the signal generator and the thin film bulk acoustic wave resonator；Wherein, described
Power amplifier is input to the thin film bulk acoustic wave resonator after the signal amplification for issuing the signal generator.
8. the method according to the description of claim 7 is characterized in that the step B, comprising:
B1, the signal generator generation high-frequency signal is controlled by a central processing unit；
Driving thin film bulk acoustic wave resonator resonance and then generation high frequency sound after B2, the high-frequency signal amplify via power amplifier
Wave；The high frequency sound wave acts on the fluid sample in the storage container, generates powerful body force and liquid is pushed to transport upwards
It is dynamic, so that forming a fluid column on the interface that fluid sample connects with oil reservoir.
9. according to the method described in claim 8, it is characterized in that, the step C, comprising:
Stop the signal output of the signal generator, so that the thin film bulk acoustic wave resonator stops generating high frequency sound wave,
So that the fluid column is fallen after rise, the surface tension at the interface is by the fluid column pinch off and forms on the interface the micro- liquid of Water-In-Oil
Drop.
10. the method according to the description of claim 7 is characterized in that the step A, further includes:
Time and the power that the signal generator generates high-frequency signal are controlled by central processing unit, to pass through the signal
Working time and the power of thin film bulk acoustic wave resonator are controlled, to pass through the working time of the thin film bulk acoustic wave resonator and function
Rate controls the generation time of the fluid column and the height and diameter of the control fluid column, to control the Water-In-Oil microlayer model
Size.
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR200470974Y1 (en) * | 2010-06-29 | 2014-01-22 | 춘밍 후앙 | Excrement automatic cleaning apparatus without taking it off |
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