CN110151110A - Fixable type gastrorrhagia monitors capsule endoscope and gastrorrhagia real-time monitoring system - Google Patents

Fixable type gastrorrhagia monitors capsule endoscope and gastrorrhagia real-time monitoring system Download PDF

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Publication number
CN110151110A
CN110151110A CN201910484319.9A CN201910484319A CN110151110A CN 110151110 A CN110151110 A CN 110151110A CN 201910484319 A CN201910484319 A CN 201910484319A CN 110151110 A CN110151110 A CN 110151110A
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CN
China
Prior art keywords
gastrorrhagia
capsule
endoscope
capsule endoscope
real
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Granted
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CN201910484319.9A
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Chinese (zh)
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CN110151110B (en
Inventor
廖专
蒋熙
潘骏
徐宏伟
李兆申
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Shanghai Changhai Hospital
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Shanghai Changhai Hospital
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/00002Operational features of endoscopes
    • A61B1/00011Operational features of endoscopes characterised by signal transmission
    • A61B1/00016Operational features of endoscopes characterised by signal transmission using wireless means
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/00131Accessories for endoscopes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/00147Holding or positioning arrangements
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/04Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor combined with photographic or television appliances
    • A61B1/041Capsule endoscopes for imaging
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/06Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor with illuminating arrangements
    • A61B1/0661Endoscope light sources
    • A61B1/0684Endoscope light sources using light emitting diodes [LED]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/273Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor for the upper alimentary canal, e.g. oesophagoscopes, gastroscopes
    • A61B1/2736Gastroscopes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/03Detecting, measuring or recording fluid pressure within the body other than blood pressure, e.g. cerebral pressure; Measuring pressure in body tissues or organs
    • A61B5/036Detecting, measuring or recording fluid pressure within the body other than blood pressure, e.g. cerebral pressure; Measuring pressure in body tissues or organs by means introduced into body tracts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/07Endoradiosondes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/42Detecting, measuring or recording for evaluating the gastrointestinal, the endocrine or the exocrine systems
    • A61B5/4222Evaluating particular parts, e.g. particular organs
    • A61B5/4238Evaluating particular parts, e.g. particular organs stomach
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/68Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6846Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive
    • A61B5/6847Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive mounted on an invasive device
    • A61B5/6861Capsules, e.g. for swallowing or implanting
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/68Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6846Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive
    • A61B5/6867Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive specially adapted to be attached or implanted in a specific body part
    • A61B5/6871Stomach

Abstract

It include capsule endoscope, connecting sleeve, portable data conversion instrument and monitor the present invention provides a kind of fixable type gastrorrhagia monitoring capsule endoscope and gastrorrhagia real-time monitoring system, gastrorrhagia real-time monitoring system.Fixed gastrorrhagia monitoring capsule endoscope includes capsule housing, endoscope fixed part, image acquiring unit, signal transport part, endoscope side microprocessor and power supply.Wherein, endoscope fixed part includes being fixed at the intracorporal Miniature negative pressure pump of nontransparent capsule shells, connecting with pump and the body of stomach tissue accommodating chamber with opening, the fine needle fixation kit that is mounted on above body of stomach tissue accommodating chamber, and fine needle fixation kit includes being mounted on that body of stomach tissue accommodates indoor pressure sensor, the micromotor that body of stomach tissue accommodates fine needle in locular wall, is fixedly mounted on nontransparent capsule housing inner wall and output end is fixedly connected with the tail end of fine needle is arranged in head end sealing insertion.

Description

Fixable type gastrorrhagia monitors capsule endoscope and gastrorrhagia real-time monitoring system
Technical field
The invention belongs to gastroenterology the field of medical instrument technology, and in particular to one kind is suitable for gastrorrhagia situation and supervises in real time The fixable type gastrorrhagia monitoring capsule endoscope and gastrorrhagia real-time monitoring system of survey.
Background technique
Acute hemorrhage of upper gastrointestinal tract means bleeding caused by the alimentary canal illness of Qu Shi ligament or more, is clinical common urgency It examines, case fatality rate is high.Wherein the most common position of upper gastrointestinal bleeding is stomach, accounts for 60% or more of entire upper gastrointestinal bleeding, out Blood lesion is most commonly seen with peptic ulcer, gastric cancer, stress ulcer, portal hypertension gastopathy.Acute hemorrhage of upper gastrointestinal tract is suffered from Person's common clinical manifestation is the peripheral circulatory failures such as spitting blood, melena symptom and dizziness, pale complexion, increased heart rate, blood pressure reduction Sign.
For the diagnosis of the gastrorrhagia cause of disease, gastroscope is the most key inspection, can detect upper gastrointestinal mucosa situation in time, The treatment such as herbal sprinkling injection, coagulation treatment heat and hemostatic clamp can be carried out to lesion in time simultaneously.But there is quite a few patient It will appear the risk of bleeding again after receiving Hemostasis through endoscopy treatment.Gastrocopy simultaneously is an invasive invasive operation, Patient has very strong sense of discomfort when checking, therefore in the clear cause of disease, moves back mirror after completing Endoscopic Treatment, can not real-time monitoring Stomach inner disease foci situation.Clinician often passes through hemoglobin in the clinical manifestations such as the spitting blood of patient, hematochezia and blood routine examination Concentration, red blood cell count(RBC) judge the amount of bleeding and bleeding of patient.
Capsule endoscope (capsule endoscopy) full name is " intelligent capsule digestive tract endoscope system ", is that one kind is made into The endoscope of capsule shape includes built-in camera shooting and signal transmitting apparatus, is allowed to move in alimentary canal by peristalsis of the digest tract And image is shot, and doctor utilizes external image recorder and image workstation, understand the entire alimentary canal situation of subject, from And diagnosis is made to its state of an illness.Capsule endoscope have small in size, hurtless measure, it is disposable, without advantages such as cross-infections.Now in The capsule endoscope of clinical application is divided into oesophagus capsule endoscope, small intestine capsule endoscope, magnetic control capsule stomach according to the difference of check point Mirror, colon capsule endoscope etc..According to the different set of capsule endoscope function, gastrointestinal pressure, pH value, power can be monitored by deriving The capsule of the different roles such as capsule.But there is presently no it is a be capable of fixing in stomach specific position stomach inner disease foci is carried out it is real-time The capsule endoscope of monitoring.
For the patient of acute gastrorrhagia in the case where carrying out positive Endoscopic Treatment, Bleeding rate is still higher again in 3 days, Once bleeding occurs again, death risk can be increased rapidly.But rely solely on the clinical manifestation of patient, hemoglobin, indicators Judge that amount of bleeding often has certain retardance, rescue cannot be implemented in first time, it is even more impossible to find out in patient's stomach Specific bleeding and healing of focus situation.Still lack at present it is a kind of can in real-time monitoring stomach situation equipment and technology, so as to Stomach internal haemorrhage situation is reminded and alarmed to clinician in time.
Summary of the invention
The present invention is to carry out to solve above-mentioned technical problem, provides one kind and is capable of fixing the specific position pair in stomach The fixable type gastrorrhagia that gastrorrhagia position carries out real-time monitoring monitors capsule endoscope, and the stomach comprising the capsule endoscope Bleeding real-time monitoring system.In order to realize that purpose, the technical solution adopted in the present invention are as follows:
<structure one>
Fixable type gastrorrhagia monitoring capsule endoscope provided by the invention has following technical characteristic: including capsule shells Body has nontransparent capsule housing and transparent capsule shell two parts;Endoscope fixed part, including be fixed at nontransparent The intracorporal Miniature negative pressure pump of capsule shells is connect and with body of stomach tissue accommodating chamber, the Yi Jian being open with the Miniature negative pressure pump Fine needle fixation kit above body of stomach tissue accommodating chamber, fine needle fixation kit are indoor including being mounted on the receiving of body of stomach tissue Pressure sensor, head end sealing are inserted into the fine needle being arranged in body of stomach tissue receiving locular wall, are fixedly mounted on nontransparent capsule shells On internal wall and micromotor that output end is fixedly connected with the tail end of fine needle;Image acquiring unit is mounted on transparent adhesive tape softgel shell In vivo, including camera and the lighting device being mounted on around camera;Signal transport part, with image acquiring unit communication link It connects, the picture signal that will acquire is transmitted outward;Endoscope side microprocessor, to endoscope fixed part, image acquiring unit and image The signal that transport part is sent is handled and generates corresponding control signal;Power supply is powered the component in endoscope.
After fixable type gastrorrhagia monitoring capsule endoscope in the present invention reaches gastrorrhagia near sites, Miniature negative pressure pump It opens, so that body of stomach tissue accommodating chamber is in negative pressure state, so that gastric tissue is attracted in accommodating chamber.Pressure sensor pair Body of stomach tissue accommodates indoor pressure and carries out real-time monitoring, and monitoring signals are passed to microprocessor, and microprocessor is to current Pressure data signal and preset value compare, and when judgement reaches preset value, send to micromotor and rotate forward control signal control Micromotor processed rotates forward, and drives fine needle to accommodate indoor moving to body of stomach tissue, penetrates body of stomach tissue and it is fixed.Work as monitoring After process, microprocessor sends reverse control signal control micromotor reversion to micromotor, drives fine needle to opposite Direction is mobile, realizes the Automatic-falling of capsule endoscope.
It preferably, further include pH value detection electricity in fixable type gastrorrhagia provided by the invention monitoring capsule endoscope Pole is separately mounted to the veutro and back side of capsule housing, detects the variation of stomach inner pH value.
Preferably, in fixable type gastrorrhagia provided by the invention monitoring capsule endoscope, signal transport part includes pH It is worth sensor, imaging sensor and wireless communication module.PH sensor is for receiving the pH that pH value detection electrode detects Value signal;Imaging sensor and camera communicate to connect, and receive the bleeding part picture of camera shooting, and utilize photoelectric device Photoelectric converting function, light image is converted into the electric signal with light image at corresponding proportion relationship;Wireless communication module passes pH value The signal that sensor and imaging sensor transmission come is transmitted outward.
Preferably, in fixable type gastrorrhagia provided by the invention monitoring capsule endoscope, nontransparent capsule housing is Semicylinder, diameter 10mm, length 30mm;Head end transparent capsule shell is 1/4 spheroid form, and diameter is also 10mm.
Preferably, in fixable type gastrorrhagia provided by the invention monitoring capsule endoscope, fine needle is that diameter is 1mm's Metal fine needle, the tail end of two fine needles are fixedly mounted in a connecting rod, the middle section of connecting rod and micromotor it is defeated Outlet is fixedly connected.
The equivalent width of fine needle length and body of stomach tissue accommodating chamber can penetrate the gastric tissue of sucking body of stomach tissue accommodating chamber, Effectively fix, metal properties ensure that the needle has certain ductility, is resistant to stomach wall to a certain degree and shrinks wriggling band The movement of the body of stomach tissue come.
Preferably, in fixable type gastrorrhagia provided by the invention monitoring capsule endoscope, lighting device is medical LED Lamp, wireless communication module are bluetooth.
<structure two>
Further, the present invention also provides a kind of gastrorrhagia real-time monitoring systems, have such technical characteristic: including knot Capsule endoscope described in structure one;Connecting sleeve connects gastroscope and capsule endoscope, and one end is gastroscope connecting pin, and the other end is Capsule endoscope connecting pin;Portable data conversion instrument is tied up in patient abdomen by bandage, is communicated to connect with capsule endoscope, It receives the signal that capsule endoscope is sent and it is handled and is stored;Monitor is communicated with portable data conversion instrument It connects, image and the pH value detected in the stomach that real-time display capsule endoscope takes.
Preferably, in gastrorrhagia real-time monitoring system provided by the invention, the gastroscope connecting pin of connecting sleeve is by transparent Medical grade rubber material is made, and makes to be tightly connected between casing and gastroscope;Connector sleeve main body is made of transparent medical rigid plastics, long Degree is 25mm;Capsule endoscope connecting pin is transparent gas cell, and material is also medical grade rubber material, is provided with charge valve Door, valve switch can connect gastroscope biopsy forceps, be opened by gastroscope biopsy forceps, the gas after opening in capsule endoscope connecting pin It releases, capsule endoscope can be detached from connecting sleeve, i.e., capsule endoscope is placed by gastroscope and connecting sleeve On stomach wall specific position.
Preferably, in gastrorrhagia real-time monitoring system provided by the invention, portable data conversion instrument include with wirelessly The signal transmission device of communication module communication connection, the conversion instrument side handled to the signal that the signal transmission device receives are micro- Processor, the data memory module stored to the processing signal of conversion instrument side microprocessor store the data The battery capacity receiver of data connection port, reception capsule endoscope battery capacity signal that module is transmitted to the monitor And the battery capacity indicator light on portable data conversion instrument surface is set.
Preferably, in gastrorrhagia real-time monitoring system provided by the invention, monitor includes monitor and movement by bed Monitor, bed side monitor are connect by data line or cordless communication network with portable data conversion instrument, real-time display capsule Image and the pH value detected in the stomach that endoscope takes, display is big, and doctor is facilitated to observe, and is applicable to repose sleeping The patient of bed;Mobile monitors are mobile phone or tablet computer, and network is connect with portable data conversion instrument by wireless communication, are fitted Patient for out-of-bed activity.
The action and effect of invention
Fixable type gastrorrhagia monitoring capsule endoscope and gastrorrhagia real-time monitoring system provided by the invention have as follows Technical effect:
Firstly, since endoscope fixed part is provided in fixable type gastrorrhagia monitoring capsule endoscope, by therein Gastric tissue is drawn into body of stomach tissue accommodating chamber by Miniature negative pressure pump, is then fixed by fine needle arrangement, thus by capsule Endoscope is fixed in gastral cavity specific position, is persistently taken pictures to lesion, achievees the purpose that obtain lesion bleeding in real time.
Patient implantation capsule endoscope, connect data conversion instrument and monitor after, can normal activity, to capsule battery When will exhaust, endoscope side microprocessor controls micromotor and reversely rotates, and fine needle is detached from from body of stomach tissue, realizes glue Capsule falls off from stomach wall automatically, and excludes from anus.Entire monitoring process is easy to operate, patient's no pain, clinician and trouble Person can observe stomach inner disease foci bleeding in real time, and the treatment and processing for bleeding patients first time again provide help.
Secondly, the fixable type gastrorrhagia in the present invention monitors in capsule endoscope and is also provided with pH value detection electrode and pH It is worth sensor, the image in addition to obtaining bleeding part, moreover it is possible to detection data is obtained by pH value, realization carries out situation in stomach More fully monitor.
Third contains connecting sleeve in gastrorrhagia real-time monitoring system of the invention, which is gastroscope Connecting pin, the other end are capsule endoscope connecting pin, and capsule endoscope is connected to gastroscope camera end (side by the connecting sleeve Visor) it can be operated.Transparent connecting sleeve allows capsule endoscope to be installed in the case where gastroscope camera lens is observed in real time, glue Capsule endoscope lens open shooting oesophagus, the real-time pictures in stomach simultaneously, and the two is same to the observation of stomach internal haemorrhage situation and lesion Step, therefore capsule fixation procedure can be realized and is accurately positioned to lesion.
4th, monitor is divided into monitor and mobile monitors by bed, and it is sleeping to be suitable for the big need of bleeding risk for monitor by bed The patient of bed, big display screen facilitate doctor and patient to check patient's stomach internal haemorrhage situation in time, and mobile monitors are made with mobile phone etc. For carrier, situation in the stomach of observation monitoring in time when facilitating patient activity.
Detailed description of the invention
Fig. 1 is the composition schematic diagram of gastrorrhagia real-time monitoring system in the embodiment of the present invention;
Fig. 2 is the surface structure schematic diagram of fixable type gastrorrhagia monitoring capsule endoscope in the embodiment of the present invention;
Fig. 3 is that fixable type gastrorrhagia monitors capsule endoscope schematic diagram of internal structure in the embodiment of the present invention;
Fig. 4 is the structural schematic diagram of connecting sleeve in the embodiment of the present invention;
Fig. 5 is the structural schematic diagram of portable data conversion instrument in the embodiment of the present invention.
Specific embodiment
Below with reference to embodiment and attached drawing, the present invention will be described in detail.But the following example should not be regarded as to the present invention The limitation of range.
In the description of the present invention, it should be noted that the orientation or position of the instructions such as term " on ", "lower", "left", "right" Setting relationship is to be based on the orientation or positional relationship shown in the drawings, and is merely for convenience of description of the present invention and simplification of the description, rather than The device or element of indication or suggestion meaning must have a particular orientation, be constructed and operated in a specific orientation, therefore cannot It is interpreted as limitation of the present invention.
Fig. 1 is the composition schematic diagram of gastrorrhagia real-time monitoring system in the embodiment of the present invention.
As shown in Figure 1, gastrorrhagia real-time monitoring system 10 includes capsule endoscope 11, connecting sleeve 12, portable data Conversion instrument 13 and monitor, the monitor include monitor 14 and 15 two types of mobile monitors by bed.
Capsule endoscope 11 is placed into stomach 100 by connecting sleeve 12 and gastroscope, logical with portable data conversion instrument 13 Letter connection, is transferred to portable data conversion instrument 13 for the stomach picture signal monitored and pH value numerical signal, by its progress Data processing, and image and pH value are transferred to monitor 14 and mobile monitors 15 by bed and carry out real-time display.
Fig. 2 is the surface structure schematic diagram of fixable type gastrorrhagia monitoring capsule endoscope in the embodiment of the present invention;Fig. 3 is Fixable type gastrorrhagia monitors capsule endoscope schematic diagram of internal structure in the embodiment of the present invention.
As shown in Figures 2 and 3, fixable type gastrorrhagia monitoring capsule endoscope is integrally in capsule shape, including capsule housing 16, and be arranged micro- in the intracorporal endoscope fixed part of shell, pH value probe portion, image acquiring unit, signal transport part, endoscope side Processor and power supply.
Capsule housing 16 includes 162 two parts of nontransparent capsule housing 161 and transparent capsule shell.Nontransparent capsule shells Body 161 is tail end, is in semicylinder shape, diameter 10mm, length 30mm;Transparent capsule shell 162 is located at head end, is 1/4 Spheroid form, diameter 10mm, mucus is not easy to be adhered to surface in stomach.
Endoscope fixed part is set in nontransparent capsule housing 161, including Miniature negative pressure pump 17, body of stomach tissue accommodating chamber 18, pressure sensor 19, fine needle 20, micromotor 21.
Miniature negative pressure pump 17 is arranged in the caudal end of nontransparent capsule housing 161, structure and principle in the prior art Miniature negative pressure pump it is identical, that is, have air exhaust nozzle, exhaust nozzle each one of one-in-and-one-out, can persistently form vacuum in entrance Or negative pressure, micro-positive pressure is formed at exhaust nozzle.In terms of working principle, and by the circular motion of motor, make inside pump every Film does reciprocating, to compress, stretch air in pump chamber and form negative pressure, generates pressure with external atmosphere pressure at bleeding point Power is poor, under the action of pressure difference, gas is sucked pump chamber, then be discharged from exhaust outlet.In the present embodiment, due to capsule endoscope Small-sized, smaller, the length about 8mm of body of stomach tissue accommodating chamber 18, width and height about 4mm or so, required negative pressure Very little, in order to save space, preferred dimension is the miniature DC motor of 3.8mm as diaphragm driving motor in Miniature negative pressure pump 17 It can meet the requirements, the overall width of Miniature negative pressure pump is in 5mm or so, and length is in 7~8mm or so.
The lower section of Miniature negative pressure pump 17, the upper right side of roof and Miniature negative pressure pump 17 is arranged in body of stomach tissue accommodating chamber 18 Air exhaust nozzle connection.Pressure sensor 19 is arranged in body of stomach tissue accommodating chamber 18 from roof insertion, carries out to the pressure in it Real-time detection.In the present embodiment, pressure sensor 19 it is small-sized, but sensitivity requirement is higher, and U.S. Entran may be selected Company production range be 2~500psi pressure sensor, diameter is only 1.27mm, due to its can place in the blood vessel into Row pressure sensitive is fully able to realize to pressure sensitive in body of stomach tissue accommodating chamber 18.
The left side of Miniature negative pressure pump 17 is arranged in fine needle 20 and micromotor 21, and micromotor 21 is miniature DC motor, It is fixedly mounted on nontransparent 161 inner wall of capsule housing, a connecting rod 22 is fixedly mounted in output end, and the both ends of connecting rod are respectively installed The head end insertion of a piece fine needle 20, fine needle is arranged in the roof of body of stomach tissue accommodating chamber 18.
The diameter of fine needle 20 is 1mm, and the equivalent width of length and body of stomach tissue accommodating chamber 18 can penetrate sucking body of stomach tissue The gastric tissue of accommodating chamber effectively fix, and metal properties ensure that the needle has certain ductility, be resistant to a certain degree The movement of stomach wall contraction wriggling bring body of stomach tissue.
The lower section of body of stomach tissue accommodating chamber 18 is arranged in pH value probe portion, is pH value detection electrode 23, is separately mounted to glue The veutro and back side of softgel shell body, detect the variation of stomach inner pH value.
Image acquiring unit corresponds to transparent capsule shell 162, including camera 24 and the illumination being mounted on around camera Device 25.In the present embodiment, lighting device 25 is preferably medical LED light.
Signal transport part includes pH sensor 26, imaging sensor 27 and wireless communication module 28.PH sensor 26 are arranged between pH value detection electrode 23, receive its pH value signal detected;Imaging sensor and 24 communication link of camera Connect, receive camera shooting bleeding part picture, and using its photoelectric device photoelectric converting function, by light image be converted to Light image at corresponding proportion relationship electric signal;Wireless communication module 28 is bluetooth, by pH sensor 26 and imaging sensor The signal that 27 transmission come is transmitted outward.
Endoscope side microprocessor 29 and Miniature negative pressure pump 17, pressure sensor 19, micromotor 21, pH sensor 26, imaging sensor 27 and wireless communication module 28 communicate to connect, and receive each detectable signal and generate corresponding control signal.
The cruise duration of power supply 30 is 3-5 days, and battery capacity is transmitted to endoscope side microprocessor 29 by electric signal mode. When battery capacity residue 10%, endoscope side microprocessor 29 controls micromotor 21 and is inverted, so that fine needle is detached from stomach Body tissue.
After fixable type gastrorrhagia monitoring capsule endoscope 11 in the present embodiment reaches gastrorrhagia near sites, endoscope Side microprocessor 29 controls Miniature negative pressure pump 17 and opens, so that body of stomach tissue accommodating chamber 18 is in negative pressure state, thus by stomach wall Tissue is attracted in accommodating chamber.Pressure sensor 19 carries out real-time monitoring to the pressure in body of stomach tissue accommodating chamber 18, and will prison It surveys signal and passes to endoscope side microprocessor 29, microprocessor compares current pressure data-signal and preset value, when When judgement reaches preset value, rotating forward control signal control micromotor is sent to micromotor 21 and is rotated forward, drives fine needle 20 to stomach Body tissue accommodates indoor moving, penetrates body of stomach tissue and it is fixed.When battery capacity residue 10% when after, microprocessor to Micromotor 21 sends reverse control signal control micromotor reversion, drives fine needle to move round about, realizes in capsule The Automatic-falling of sight glass.
Fig. 4 is the structural schematic diagram of connecting sleeve in the embodiment of the present invention.
As shown in Figure 1 and Figure 4, connecting sleeve 12 connects gastroscope and capsule endoscope 11, the gastroscope connecting pin of connecting sleeve 121 are made of transparent medical grade rubber material, make to be tightly connected between casing and gastroscope;Connecting sleeve main body 122 is by transparent medical Rigid plastics is made, length 25mm;Capsule endoscope connecting pin 123 is transparent gas cell, and material is also medical grade rubber material, It is provided with charging valve 123a, valve switch can connect gastroscope biopsy forceps, open by gastroscope biopsy forceps, capsule after opening Gas in endoscope connecting pin is released, and capsule endoscope can be detached from connecting sleeve, so that capsule endoscope is logical It crosses gastroscope and connecting sleeve is placed on stomach wall specific position.
Fig. 5 is the structural schematic diagram of portable data conversion instrument in the embodiment of the present invention.
As shown in figure 5, portable data conversion instrument 13 is tied up by bandage 31 in patient abdomen, with capsule endoscope communication link It connects, receive the signal that capsule endoscope is sent and it is handled and is stored.It is set inside the portable data conversion instrument 13 It is equipped with signal transmission device 32, conversion instrument side microprocessor 33, data memory module 34, data connection port 35, capsule battery electricity Measure receiver 36 and power supply 37;Surface is provided with power switch 38, fixed button 39 and capsule battery capacity indicator light 40.
Signal transmission device 31 is also bluetooth, is communicated to connect with wireless communication module 28, receives wireless communication module 28 and transmits Viewdata signal, pH value data-signal and the time tag come;Conversion instrument side microprocessor 33 receives these data-signals It is stored into data memory module 34 afterwards;Data in data memory module 34 can be by data connection port 35 and bed by Monitor 14 connects or imports data to computer terminal and stored and analyzed, and by cordless communication networks such as bluetooths and can also move Dynamic monitor 15 connects;Capsule battery capacity receiver 36 receives capsule endoscope battery capacity signal, and directly electric with capsule Pond battery capacity indication lamp 37 is connected, and when capsule battery capacity abundance, indicator light is green, when capsule battery capacity is less than 10%, Indicator light reddens, and when capsule dead battery, indicator light does not develop the color.In actual use, when capsule battery capacity is less than When 10%, conversion instrument side microprocessor 33 passes through signal transmission device 31 and wireless communication module 28 to endoscope side microprocessor 29 Control signal is sent, endoscope side microprocessor 29 controls micromotor 21 according to the control signal and inverts, and allows capsule endoscope Automatic-falling.
Monitor includes monitor 14 and mobile monitors 15 by bed, and monitor 14 is converted by data line or bluetooth by bed Device is connect with portable data conversion instrument 13, image and the pH value detected in the stomach that real-time display capsule endoscope takes, Its display is big, and doctor is facilitated to observe, the patient for the bed that is applicable to repose;Mobile monitors 15 are mobile phone or plate electricity Brain, network is connect with portable data conversion instrument 13 by wireless communication, the patient suitable for out-of-bed activity.
The application method of gastrorrhagia real-time monitoring system in the present embodiment is as follows:
Before patient's row fixable type capsule endoscope 11 is implanted into, leading tradition side-viewing gastrofiberscopy stomach internal haemorrhage feelings Condition specifies stigma property and position, while assessment is conducive to fixed capsule endoscope and has to monitoring gastrorrhagia lesion good Position in the stomach in the good visual field.
Start fixable type gastrorrhagia and monitor capsule endoscope 11, opens simultaneously prison by portable data conversion instrument 13 and bed Visual organ 14 checks capsule endoscope camera lens shooting function and pH writing function.When determining that operation of capsule endoscope state is normal, Fixable type gastrorrhagia monitoring capsule endoscope 11 is connected to gastroscope head end by connecting sleeve 12, after the completion of connection, is passed through Charging valve is inflated in the air bag of capsule endoscope connecting pin, connect capsule endoscope closely with connecting sleeve.In fiber Detecting down in real time for two camera lenses of gastroscope and capsule endoscope, finds stomach internal haemorrhage position and be suitable for installing capsule and having good view Open country carries out the position of real-time monitoring lesion.
After determining good position, the fixed button on portable data conversion instrument 13 is clicked, endoscope side microprocessor 29 is controlled Miniature negative pressure pump 17 processed is opened, so that negative pressure state is formed in body of stomach tissue accommodating chamber 18, so that gastric tissue is attracted to appearance Receive interior.Pressure sensor 19 carries out real-time monitoring to the pressure in body of stomach tissue accommodating chamber 18, and monitoring signals are passed to Endoscope side microprocessor 29, microprocessor compares current pressure data-signal and preset value, when judgement reaches default When value, is sent to micromotor 21 and rotate forward control signal control micromotor rotating forward, drive fine needle 20 to body of stomach tissue accommodating chamber Interior movement penetrates body of stomach tissue and it is fixed, realizes the fixation of capsule endoscope.
Camera 24 shoots photo under the auxiliary of lighting device 25, to bleeding part, and is received by imaging sensor 27, It is mounted on the variation of the 23 real-time detection stomach inner pH value of pH value detection electrode of capsule veutro and back side simultaneously, and is transmitted to pH value biography Sensor 26.Imaging sensor 27 and pH sensor 26 by wireless communication module 28 by collected data-signal together with the time Label is transferred to portable data conversion instrument 13, is analyzed and processed, keeps in data and carries out real-time display by monitor.
When capsule endoscope battery capacity residue 10%, microprocessor sends reverse control signal control to micromotor 21 Micromotor reversion processed, drives fine needle to move round about, realizes the Automatic-falling of capsule endoscope.
The basic principles, main features and advantages of the present invention have been shown and described above.The technology of the industry Personnel are it should be appreciated that the present invention is not limited to the above embodiments, and the above embodiments and description only describe this The principle of invention, various changes and improvements may be made to the invention without departing from the spirit and scope of the present invention, these changes Change and improvement all fall within the protetion scope of the claimed invention.The claimed scope of the invention by appended claims and its Equivalent defines.

Claims (10)

1. a kind of fixable type gastrorrhagia monitors capsule endoscope, it is capable of fixing near stomach bleeding part, to stomach inner disease foci Carry out real-time monitoring comprising:
Capsule housing, including nontransparent capsule housing and transparent capsule shell two parts;
Endoscope fixed part, including it is fixed at the intracorporal Miniature negative pressure pump of the nontransparent capsule shells and the Minitype negative pressure Pump connects and the body of stomach tissue accommodating chamber with opening and the fine needle being mounted on above the body of stomach tissue accommodating chamber are fixed Component, the fine needle fixation kit include being mounted on the body of stomach tissue to accommodate indoor pressure sensor, head end sealing insertion The body of stomach tissue is arranged in accommodate fine needle in locular wall, be fixedly mounted on the nontransparent capsule housing inner wall and export Hold the micromotor being fixedly connected with the tail end of the fine needle;
Image acquiring unit is mounted in the transparent capsule shell, including camera and is mounted on around the camera Lighting device;
Signal transport part, communicates to connect with described image acquisition unit, and the picture signal that will acquire is transmitted outward;
Endoscope side microprocessor, the signal that the endoscope fixed part, image acquiring unit and image transmitting portion are sent into Row handles and generates corresponding control signal;
Power supply is powered the component in endoscope.
2. fixable type gastrorrhagia according to claim 1 monitors capsule endoscope, which is characterized in that further include:
PH value detection electrode is separately mounted to the veutro and back side of the capsule housing.
3. fixable type gastrorrhagia according to claim 1 monitors capsule endoscope, it is characterised in that:
Wherein, the nontransparent capsule housing is semicylinder, diameter 10mm, length 30mm;The head end transparent capsule Shell is 1/4 spheroid form, and diameter is also 10mm.
4. fixable type gastrorrhagia according to claim 1 monitors capsule endoscope, it is characterised in that:
Wherein, the fine needle is the metal fine needle that diameter is 1mm, and the tail end end of two fine needles is fixedly mounted on a connecting rod On, the middle section of the connecting rod is fixedly connected with the output end of the micromotor.
5. fixable type gastrorrhagia according to claim 2 monitors capsule endoscope, it is characterised in that:
Wherein, the signal transport part includes pH sensor, imaging sensor and wireless communication module, the radio communication mold Block transmits the signal that the pH sensor and imaging sensor transmission are come outward.
6. fixable type gastrorrhagia according to claim 5 monitors capsule endoscope, it is characterised in that:
Wherein, the lighting device is medical LED light, and the wireless communication module is bluetooth.
7. a kind of gastrorrhagia real-time monitoring system characterized by comprising
The described in any item capsule endoscopes of claim 1~6;
Connecting sleeve connects gastroscope and capsule endoscope, and one end is gastroscope connecting pin, and the other end is capsule endoscope connecting pin;
Portable data conversion instrument is tied up in patient abdomen by bandage, communicates to connect with the capsule endoscope, receive the glue Signal that intracapsular sight glass is sent simultaneously handles it and is stored;
Monitor is communicated to connect with the portable data conversion instrument, in the stomach that capsule endoscope described in real-time display takes Image and the pH value detected.
8. gastrorrhagia real-time monitoring system according to claim 7, it is characterised in that:
Wherein, the gastroscope connecting pin of the connecting sleeve is made of medical translucent rubber material, and intermediate body portion is by transparent doctor It is made of rigid plastics, length 25mm, capsule endoscope connecting pin is transparent gas cell, is provided with charging valve.
9. gastrorrhagia real-time monitoring system according to claim 7, it is characterised in that:
Wherein, the portable data conversion instrument includes with the signal transmission device of wireless communication module communication connection, to the letter Conversion instrument side microprocessor that the signal that number transmitter receives is handled believes the processing of conversion instrument side microprocessor Number data memory module stored, by data connection port that the data memory module is transmitted to the monitor, connect It receives the battery capacity receiver of capsule endoscope battery capacity signal and is arranged on portable data conversion instrument surface Battery capacity indicator light.
10. gastrorrhagia real-time monitoring system according to claim 7, it is characterised in that:
Wherein, the monitor includes monitor and mobile monitors by bed, and monitor passes through data line or wireless by the bed Communication network is connect with the portable data conversion instrument, and the mobile monitors are mobile phone or tablet computer, passes through channel radio Communication network is connect with the portable data conversion instrument.
CN201910484319.9A 2019-06-05 2019-06-05 Fixable capsule endoscope for monitoring gastrorrhagia and real-time monitoring system for gastrorrhagia Active CN110151110B (en)

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