CN109821093B - Piezoelectric stack driven infusion set - Google Patents

Piezoelectric stack driven infusion set Download PDF

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Publication number
CN109821093B
CN109821093B CN201910166691.5A CN201910166691A CN109821093B CN 109821093 B CN109821093 B CN 109821093B CN 201910166691 A CN201910166691 A CN 201910166691A CN 109821093 B CN109821093 B CN 109821093B
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cavity
cavities
sinking
outlet
inlet
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CN109821093A (en
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张忠华
陈泽锋
唐姣
王淑云
温建明
杨泽盟
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Zhejiang Normal University CJNU
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Zhejiang Normal University CJNU
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Abstract

The invention relates to a piezoelectric stack driven infusion device, and belongs to the field of medical instruments. The base is provided with an inlet hole, an outlet cavity and at least two sinking cavities with different diameters, the diameters of the sinking cavities are sequentially reduced from left to right, and the bottom wall of each sinking cavity is provided with an inlet cavity and an outlet hole; the inlet and outlet cavities and the valve plates arranged in the inlet and outlet cavities respectively form an inlet and outlet valve; the bottom of the main body is provided with guide holes with the number and the diameter equal to those of the sinking cavities respectively, the main body is arranged on the base and presses the diaphragm on the base, and the guide holes and the sinking cavities are symmetrically arranged at two sides of the diaphragm; the piezoelectric stack in the guide hole presses the piston on the diaphragm; the diaphragm presses the sealing ring in the sinking cavity to form compression cavities which are connected in series; the top of the main body is provided with a bag cavity in which an air bag and a medicine bag are arranged, and the end part of the side wall of the bag cavity is provided with a baffle plate; a liquid outlet pipe of the medicine bag is provided with a flow regulating valve and a needle head, an air inlet pipe of the air bag is connected with an outlet hole of the base, and an air inlet pipe of the air bag is provided with a switch valve and an air release valve; in operation, the deformation directions of the diaphragms in two adjacent compression chambers are opposite.

Description

Piezoelectric stack driven infusion set
Technical Field
The invention belongs to the field of medical instruments, and particularly relates to a piezoelectric stack driven infusion device.
Background
The injection administration mainly comprises intravenous injection, intramuscular injection, subcutaneous injection and the like. Intravenous injection is also called infusion administration, and most of the existing infusion devices are composed of an infusion bottle, an infusion tube and an infusion support, wherein the infusion bottle is hung on the infusion support, flows by the self weight of liquid medicine and is injected into a blood vessel of a person through the infusion tube. This infusion mode brings about many problems in practical use: the flow is adjusted by a manual method, and the flow control precision is insufficient; the patient needs to lift the infusion bottle by others when walking or going to the toilet, and the like, so that the movement is inconvenient and the blood can flow back when the height of the infusion bottle is not enough; the patient or the nursing staff is required to watch for a long time, and if the completion of the infusion is not found in time, accidents can be caused; the liquid medicine contacts with air, and the pollution possibility exists when the ambient air is unclean. In addition to the above direct problems, the infusion time is sometimes shortened by reducing the amount of solution, increasing the infusion speed, and the like, which not only burdens the heart, but also affects the therapeutic effect: the most important disadvantage of intramuscular injection and subcutaneous injection, which inject drugs into muscle or subcutaneous tissue in a relatively short time, is that the difference of blood drug concentration is large in one injection period, which is not favorable for effective absorption and utilization of drugs because: most drugs have a better concentration range in human body, and have toxic and side effects when the concentration of the drugs is too high, and have no treatment effect when the concentration of the drugs is too low. Therefore, a miniature portable controlled drug delivery device or system that can prolong the drug injection time and maintain reasonable drug concentration is urgently needed in the medical field.
Disclosure of Invention
The invention provides a piezoelectric stack driven infusion device, which comprises the following implementation schemes: the base is provided with an inlet hole, an outlet cavity and at least two sinking cavities with different diameters, the diameters of the sinking cavities are sequentially reduced from left to right, and the bottom wall of each sinking cavity is provided with an inlet cavity and an outlet hole; the inlet cavity of the leftmost sinking cavity is communicated with the inlet hole, the air outlet hole of the rightmost sinking cavity is communicated with the outlet hole through the outlet cavity, and the inlet cavities and the air outlet holes of the other two adjacent sinking cavities are communicated; the inlet and outlet cavities and valve plates arranged in the inlet and outlet cavities respectively form an inlet and outlet valve, and the valve plates are cantilever beam valves or butterfly valves; the bottom of the main body is provided with guide holes with the number and the diameter equal to those of the sinking cavities respectively, the main body is arranged on the base through screws and presses the diaphragm on the base, and the guide holes and the sinking cavities are symmetrically arranged on the upper side and the lower side of the diaphragm; the piezoelectric stack and the piston are arranged in the guide hole, the piston is pressed on the diaphragm by the main body through the piezoelectric stack, the piston is T-shaped, the small end of the piston is contacted with the diaphragm, and the side wall of the large end of the piston is contacted with the inner wall of the guide hole; the diaphragm presses the sealing ring in the sinking cavity to form compression cavities, and the compression cavities are connected in series; the top of the main body is provided with a bag cavity, the end part of the side wall of the bag cavity is provided with a chute, an air bag and a medicine bag are arranged in the bag cavity from bottom to top, and a baffle is arranged in the chute at the end part of the side wall of the bag cavity; a liquid outlet pipe of the medicine bag is provided with a flow regulating valve and a needle head, an air inlet pipe of the air bag is connected with an outlet hole of the base, and an air inlet pipe of the air bag is provided with a switch valve and an air release valve; in operation, the deformation directions of the diaphragms in the two adjacent compression cavities are opposite, and the volume variation of the larger static volume in the two compression cavities which are communicated with each other is not less than the volume variation of the smaller static volume.
Taking an infusion device with three compression cavities as an example, the guide holes are sequentially defined as a guide hole I, a guide hole II and a guide hole III from left to right, the sinking cavities are sequentially defined as a sinking cavity I, a sinking cavity II and a sinking cavity III, the compression cavities are sequentially defined as a compression cavity I, a compression cavity II and a compression cavity III, the inlet valves are sequentially defined as an inlet valve II and a compression cavity III, and the pistons; the specific working process is as follows: in the first half cycle, the piezoelectric stacks in the first guide hole and the third guide hole are extended, the piezoelectric stacks in the second guide hole are shortened, the volumes of the first compression cavity and the third compression cavity are reduced, the volumes of the second compression cavity are increased, the first inlet valve and the third inlet valve are opened, the second inlet valve and the second outlet valve are closed, the first compression cavity and the third compression cavity suck gas, and the second compression cavity discharges gas, which is a suction process; in the second half cycle, the piezoelectric stacks in the first and third guide holes are shortened, the piezoelectric stacks in the second guide hole are extended, the volumes of the first and third compression cavities are increased, the volumes of the second compression cavity are reduced, the first and third inlet valves are closed, the second inlet valve and the second outlet valve are opened, the first and third compression cavities discharge gas, and the second compression cavity sucks gas, which is a discharge process; in the suction and discharge processes, the gas undergoes the progressive accumulation compression of the first, second and third compression cavities, and the output pressure is high; when the switch valve is opened and the air release valve is closed, air enters the air bag from the outlet hole through the air inlet pipe and the switch valve, the volume of the air bag expands and compresses the medicine bag, the internal pressure of the medicine bag increases, and medicine liquid is output; when the deflation valve is opened and the switch valve is closed, the gas in the air bag is discharged through the deflation valve, and the medicine bag is replaced for repeated transfusion.
In the present invention, the maximum gas storage pressure of the airbag is Pmax=P0ηp{(1+α)/(1-α)[β+(1+α)/(1-α)]n-1-1}, wherein: p0Is standard atmospheric pressure, etapFor the efficiency coefficient, alpha is more than 0 and is a compression ratio, namely the ratio of the volume change of a compression cavity caused by the deformation of the piezoelectric stack to the volume of the compression cavity, beta is more than 1 and is the radius ratio of two left and right adjacent compression cavities, and n is more than or equal to 2 and is the number of the compression cavities; in order to obtain the maximum compression ratio, the optimal radius ratio of the small end to the large end of the piston is respectively 0.79, 0.65 and 0.55 when the diaphragm is beryllium bronze with the thickness of 0.1, 0.2 and 0.3mm, and the height of the compression cavity is the elongation of the piezoelectric stack under the action of voltage; two adjacent compression chambersWhen the valve plates are communicated, namely the valve plates between the two are opened, the volume change quantity of the compression cavity with the larger radius is not less than that of the compression cavity with the smaller radius.
Advantages and features: the output of the liquid medicine is controlled by the coupling action of the piezoelectric driver and the gas, so that the transfusion speed is easily and accurately controlled by the driving voltage; a hanging device is not needed during intravenous injection, and the intravenous injection device is convenient to move and carry; the liquid medicine is not contacted with the air, the phenomena of liquid medicine pollution, gas entering blood vessels, blood backflow and the like can not occur, real-time watching is not needed, and the device is safe and reliable; when the injection is injected into muscles and subcutaneous tissues, the injection time can be prolonged as required, the problem of uneven blood concentration in a human body caused by manual rapid injection is avoided, and the curative effect of the medicine is improved.
Drawings
FIG. 1 is a cross-sectional view of the structure of an infusion set in accordance with a preferred embodiment of the present invention;
FIG. 2 is a schematic structural diagram of a main body according to a preferred embodiment of the present invention;
FIG. 3 is a top view of FIG. 2;
FIG. 4 is a schematic structural diagram of a base in a preferred embodiment of the present invention;
FIG. 5 is a top view of FIG. 4;
fig. 6 is a schematic view of the infusion set in an operative condition in accordance with a preferred embodiment of the present invention.
Detailed Description
An inlet hole b1, at least two sinking cavities b2i with different diameters, an outlet cavity b3 and an outlet hole b6 are arranged on the base b, the diameters of the sinking cavities b2i are sequentially reduced from left to right, an inlet cavity b4 and an outlet hole b5 are arranged on the bottom wall of the sinking cavity b2i, an inlet cavity b4 of the leftmost sinking cavity b2i is communicated with the inlet hole b1, an outlet hole b5 of the rightmost sinking cavity b2i is communicated with the outlet hole b6 through an outlet cavity b3, and inlet cavities b4 and outlet holes b5 of the other two adjacent sinking cavities b2i are communicated with each other; the inlet cavity b4 and the outlet cavity b3 and a valve plate f arranged in the inlet cavity b4 and the outlet cavity b3 form an inlet valve vi and an outlet valve v respectively, and the valve plate f is a cantilever beam valve or a butterfly valve; the bottom of the main body a is provided with guide holes a2i which are respectively equal to the number and the diameter of the sinking cavities b2 i; the main body a is arranged on a base b through a screw, a diaphragm g is pressed on the base b, and the guide holes a2i and the sinking cavities b2i are symmetrically arranged on the upper side and the lower side of the diaphragm g; the piezoelectric stack d and the piston ei are arranged in the guide hole a2i, the piston ei is pressed on the diaphragm g by the main body a through the piezoelectric stack d, the piston ei is T-shaped, the small end of the piston ei is in contact with the diaphragm g, and the side wall of the large end of the piston ei is in contact with the inner wall of the guide hole a2 i; the diaphragm g presses the sealing ring in the sinking cavity b2i to form compression cavities Ci which are connected in series; the top of the main body a is provided with a capsule cavity a1, the end part of the side wall of the capsule cavity a1 is provided with a sliding chute a3, an air bag y and a medicine bag z are arranged in the capsule cavity a1 from bottom to top, and a baffle j is arranged in the sliding chute a3 at the end part of the side wall of the capsule cavity a 1; a flow regulating valve k and a needle head are arranged on a liquid outlet pipe q of the medicine bag z, an air inlet pipe of the air bag y is connected with an outlet hole b6 of the base b, and a switch valve h1 and a release valve h2 are arranged on the air inlet pipe of the air bag y; in operation, the deformation directions of the diaphragms g in the two adjacent compression cavities Ci are opposite, and the volume variation of the larger static volume in the two compression cavities which are communicated with each other is not less than the volume variation of the smaller static volume.
In the invention, i in the guide hole a2i, the sinking chamber b2i, the compression chamber Ci, the inlet valve vi and the piston ei represents serial numbers from left to right, and i is 1,2,3 and …; taking an infusion device with three compression chambers Ci as an example, from left to right, the guide hole a2i is sequentially defined as a guide hole I21, a guide hole II 22 and a guide hole III 23, the sinking chamber B2i is sequentially defined as a sinking chamber I b21, a sinking chamber II b22 and a sinking chamber III b23, the compression chambers Ci are sequentially defined as a compression chamber I C1, a compression chamber II C2 and a compression chamber III C3, the inlet valve VI is sequentially defined as an inlet valve I v1, a compression chamber II v2 and a compression chamber III v3, and the pistons ei are sequentially defined as pistons I1, II e2 and III e 3; the specific working process is as follows: in the upper half cycle, the piezoelectric stack d in the first guide hole a1 and the third guide hole a3 is extended, the piezoelectric stack d in the second guide hole a2 is shortened, the volumes of the first compression cavity C1 and the third compression cavity C3 are reduced, the volume of the second compression cavity C2 is increased, the first inlet valve v1 and the third compression cavity V3 are opened, the second inlet valve v2 and the outlet valve v are closed, the first compression cavity C1 and the third compression cavity C3 suck gas, and the second compression cavity C2 discharges gas, so that the suction process is realized; in the second half cycle, the piezoelectric stack d in the first guide hole a1 and the third guide hole a3 is shortened, the piezoelectric stack d in the second guide hole a2 is lengthened, the volumes of the first compression cavity C1 and the third compression cavity C3 are increased, the volume of the second compression cavity C2 is reduced, the first inlet valve v1 and the third compression cavity V3 are closed, the second inlet valve v2 and the outlet valve v are opened, the first compression cavity C1 and the third compression cavity C3 exhaust gas, and the second compression cavity C2 sucks gas, which is the exhaust process; in the suction and discharge processes, the gas undergoes the progressive accumulated compression of the compression cavities I C1, II C2 and III C3, and the output pressure is high; when the switch valve h1 is opened and the air release valve h2 is closed, air enters the air bag y from the outlet hole b6 through the air inlet pipe and the switch valve h1, the volume of the air bag y expands and compresses the medicine bag z, the internal pressure of the medicine bag z is increased, and liquid medicine is output; when the air release valve h2 is opened and the switch valve h1 is closed, the air in the air bag y is discharged through the air release valve h2, and the infusion is repeated by replacing the medicine bag z.
In the present invention, the maximum storage pressure of the air bag y is Pmax=P0ηp{(1+α)/(1-α)[β+(1+α)/(1-α)]n-1-1}, wherein: p0Is standard atmospheric pressure, etapFor the efficiency coefficient, alpha is more than 0 and is a compression ratio, namely the ratio of the volume change quantity of the compression cavity Ci caused by the deformation of the piezoelectric stack d to the volume of the compression cavity Ci, beta is more than 1 and is the radius ratio of the two left and right adjacent compression cavities Ci, and n is more than or equal to 2 and is the number of the compression cavities Ci; in order to obtain the maximum compression ratio, the optimal radius ratio of the small end to the large end of the piston ei is respectively 0.79, 0.65 and 0.55 when the diaphragm g is beryllium bronze with the thickness of 0.1, 0.2 and 0.3mm, and the height of the compression cavity Ci is the elongation of the piezoelectric stack d under the action of voltage; when two adjacent compression cavities Ci are communicated with each other, namely the valve plate f between the two adjacent compression cavities is opened, the volume change quantity of the compression cavity Ci with the larger radius is not less than that of the compression cavity Ci with the smaller radius.

Claims (1)

1. A piezoelectric stack driven infusion device is characterized in that: the base is provided with an inlet hole, an outlet cavity and at least two sinking cavities with different diameters, the diameters of the sinking cavities are sequentially reduced from left to right, and the bottom wall of each sinking cavity is provided with an inlet cavity and an outlet hole; the inlet cavity of the leftmost sinking cavity is communicated with the inlet hole, the air outlet hole of the rightmost sinking cavity is communicated with the outlet hole through the outlet cavity, and the inlet cavities and the air outlet holes of the other two adjacent sinking cavities are communicated; the inlet and outlet cavities and the valve plates arranged in the inlet and outlet cavities respectively form an inlet and outlet valve; the bottom of the main body is provided with guide holes with the number and the diameter equal to those of the sinking cavities respectively, the main body is arranged on the base and presses the diaphragm on the base, and the guide holes and the sinking cavities are symmetrically arranged on the upper side and the lower side of the diaphragm; the piezoelectric stack and the piston are arranged in the guide hole, the piston is pressed on the diaphragm by the main body through the piezoelectric stack, the piston is T-shaped, and the small end of the piston is contacted with the diaphragm; the diaphragm presses the sealing ring toCompression cavities are formed in the sinking cavity and are connected in series; when the diaphragm is a beryllium bronze film with the thickness of 0.1mm, 0.2mm and 0.3mm, the optimal diameter ratio of the small end to the large end of the piston is respectively 0.79, 0.65 and 0.55, and the height of the compression cavity is the elongation of the piezoelectric stack under the action of voltage; the top of the main body is provided with a bag cavity, an air bag and a medicine bag are arranged in the bag cavity, and the end part of the side wall of the bag cavity is provided with a baffle; a liquid outlet pipe of the medicine bag is provided with a flow regulating valve and a needle head, an air inlet pipe of the air bag is connected with an outlet hole of the base, and an air inlet pipe of the air bag is provided with a switch valve and an air release valve; when the two adjacent compression cavities are communicated with each other, the volume variation of the compression cavity with larger radius is not less than that of the compression cavity with smaller radius; the maximum gas storage pressure of the air bag is Pmax=P0ηp{(1+α)/(1-α)[β+(1+α)/(1-α)]n-1-1}, wherein: p0Is standard atmospheric pressure, etapFor the efficiency coefficient, alpha is more than 0, the compression ratio, beta is more than 1, the radius ratio of two adjacent compression cavities is about, and n is more than or equal to 2, and the number of the compression cavities is equal to or more than 2.
CN201910166691.5A 2019-03-01 2019-03-01 Piezoelectric stack driven infusion set Active CN109821093B (en)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH07301180A (en) * 1994-05-02 1995-11-14 Tosoh Corp Piezoelectric pump
EP1536140A1 (en) * 2003-11-27 2005-06-01 Aisin Seiki Kabushiki Kaisha Multistage dry vacuum pump
CN2673410Y (en) * 2004-02-14 2005-01-26 王新明 External wound serious patient fast pressurized transfusion device
CN202108708U (en) * 2011-06-24 2012-01-11 浙江师范大学 Piezoelectric stack pump with sensor
CN102678528A (en) * 2012-05-23 2012-09-19 浙江师范大学 Series-parallel hybrid-driven piezoelectric pump
CN102817817A (en) * 2012-05-23 2012-12-12 南京航空航天大学 Piezo-stack pump
CN106014940A (en) * 2016-06-15 2016-10-12 浙江师范大学 Diaphragm pump driven by chip piezoelectric vibrators
JP2019031946A (en) * 2017-08-09 2019-02-28 株式会社村田製作所 Fluid control device, sphygmomanometer, milking machine and negative-pressure wound therapy device
CN109125849A (en) * 2018-06-30 2019-01-04 武汉佰起科技有限公司 A kind of infusion device under field condition

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