CN109580937A - Full-automatic detection card - Google Patents
Full-automatic detection card Download PDFInfo
- Publication number
- CN109580937A CN109580937A CN201811497929.4A CN201811497929A CN109580937A CN 109580937 A CN109580937 A CN 109580937A CN 201811497929 A CN201811497929 A CN 201811497929A CN 109580937 A CN109580937 A CN 109580937A
- Authority
- CN
- China
- Prior art keywords
- detection card
- film bar
- reaction cup
- test paper
- cover board
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 238000001514 detection method Methods 0.000 title claims abstract description 124
- 238000006243 chemical reaction Methods 0.000 claims abstract description 95
- 238000012360 testing method Methods 0.000 claims abstract description 56
- 238000002615 hemofiltration Methods 0.000 claims abstract description 26
- 238000010521 absorption reaction Methods 0.000 claims abstract description 15
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 15
- 238000011088 calibration curve Methods 0.000 claims description 7
- 239000007788 liquid Substances 0.000 abstract description 13
- 239000003153 chemical reaction reagent Substances 0.000 abstract description 3
- 238000013473 artificial intelligence Methods 0.000 abstract description 2
- 239000000523 sample Substances 0.000 description 30
- 101100327917 Caenorhabditis elegans chup-1 gene Proteins 0.000 description 28
- 238000004587 chromatography analysis Methods 0.000 description 6
- 239000000463 material Substances 0.000 description 5
- 238000010586 diagram Methods 0.000 description 4
- 238000000034 method Methods 0.000 description 4
- 239000002253 acid Substances 0.000 description 3
- 238000004458 analytical method Methods 0.000 description 3
- 238000007689 inspection Methods 0.000 description 3
- 239000000203 mixture Substances 0.000 description 3
- NJPPVKZQTLUDBO-UHFFFAOYSA-N novaluron Chemical compound C1=C(Cl)C(OC(F)(F)C(OC(F)(F)F)F)=CC=C1NC(=O)NC(=O)C1=C(F)C=CC=C1F NJPPVKZQTLUDBO-UHFFFAOYSA-N 0.000 description 3
- 238000000926 separation method Methods 0.000 description 3
- 239000000243 solution Substances 0.000 description 3
- 239000005030 aluminium foil Substances 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 238000011010 flushing procedure Methods 0.000 description 2
- 150000003839 salts Chemical class 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- 230000005526 G1 to G0 transition Effects 0.000 description 1
- 238000005377 adsorption chromatography Methods 0.000 description 1
- 150000001413 amino acids Chemical class 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 238000004140 cleaning Methods 0.000 description 1
- 239000013013 elastic material Substances 0.000 description 1
- 239000004744 fabric Substances 0.000 description 1
- PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 description 1
- 239000010931 gold Substances 0.000 description 1
- 229910052737 gold Inorganic materials 0.000 description 1
- 238000009434 installation Methods 0.000 description 1
- 230000003993 interaction Effects 0.000 description 1
- 239000011259 mixed solution Substances 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 108020004707 nucleic acids Proteins 0.000 description 1
- 102000039446 nucleic acids Human genes 0.000 description 1
- 150000007523 nucleic acids Chemical class 0.000 description 1
- 150000002894 organic compounds Chemical class 0.000 description 1
- 239000005416 organic matter Substances 0.000 description 1
- 238000004810 partition chromatography Methods 0.000 description 1
- 230000000704 physical effect Effects 0.000 description 1
- 239000004033 plastic Substances 0.000 description 1
- 229920003023 plastic Polymers 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 238000003908 quality control method Methods 0.000 description 1
- 239000012488 sample solution Substances 0.000 description 1
- 230000004304 visual acuity Effects 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54366—Apparatus specially adapted for solid-phase testing
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/558—Immunoassay; Biospecific binding assay; Materials therefor using diffusion or migration of antigen or antibody
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/00029—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor provided with flat sample substrates, e.g. slides
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/00029—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor provided with flat sample substrates, e.g. slides
- G01N2035/00099—Characterised by type of test elements
- G01N2035/00148—Test cards, e.g. Biomerieux or McDonnel multiwell test cards
Landscapes
- Health & Medical Sciences (AREA)
- Immunology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Biotechnology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
Abstract
The present invention relates to medical instruments fields, provide a kind of full-automatic detection card, comprising: detection card ontology, film bar cover board and at least one Test paper；The surface for detecting card ontology is equipped at least one first reaction cup and at least one film bar groove；Test paper is placed in film bar groove；Test paper includes the hemofiltration pad, inner membrance item and water absorption pad being sequentially connected；Film cover plate lid is closed on Test paper；And opposite place is equipped with well with hemofiltration pad on film bar cover board；Another surface for detecting card ontology is equipped with transparent scanning area, and scanning area is opposite with inner membrance item.Full-automatic detection card provided by the invention is by the way that the first reaction cup and well to be all integrated on a surface of detection card ontology, and transparent scanning area is equipped on another surface of reagent card ontology, detection card is facilitated to be matched with Artificial Intelligence Instrument, reduce pollution etc., and the mixing of buffer and sample liquid can be completed on detection card, improve the convenience of detection card.
Description
Technical field
The present invention relates to medical instruments fields, more particularly to a kind of full-automatic detection card.
Background technique
Chromatography (chromatography) is the abbreviation of " chromatographic analysis ".It, will be more using the difference of each component physical property
Component mixture carries out separation and method for measuring.There is two kinds of adsorption chromatography, Partition Chromatography.It is generally used for organic compound, gold
Belong to the analysis of ion, amino acid etc..The chromatography allocation proportion different between stationary phase and mobile phase using substance, reaches separation
The technology of purpose.Chromatographing the analysis of the separation to the mixture of the organic matter of the complexity such as large biological molecule such as protein and nucleic acid has pole
High resolving power.
Detection card is mainly used in chromatography detection to detect sample liquid.The detection card of the prior art includes upper cover, pedestal
And Test paper, upper lid are equipped with well and read window, pedestal is equipped with test paper slot, and Test paper is set in test paper slot,
Upper cover is connect with pedestal.But existing detection is stuck in when being used cooperatively with analyzer, operating efficiency is lower.
Summary of the invention
(1) technical problems to be solved
The object of the present invention is to provide a kind of full-automatic detection cards, it is intended at least solve the prior art or deposit in the related technology
The technical issues of one of.
(2) technical solution
In order to solve the above technical problem, the present invention provides a kind of full-automatic detection cards, comprising: detection card ontology, film item
Cover board and at least one Test paper；One surface of the detection card ontology is equipped at least one first reaction cup, Yi Jizhi
A few film bar groove；First reaction cup is for filling buffer and sample to be tested；The Test paper is placed on the film item
In slot；The Test paper includes the hemofiltration pad, inner membrance item and water absorption pad being sequentially connected, the inner membrance item be equipped with detection line and
Nature controlling line；The film cover plate lid is closed on the Test paper, so that the Test paper is fastened in the film bar groove；And
Opposite place is equipped with well with the hemofiltration pad on the film bar cover board；Another surface of the detection card ontology, which is equipped with, sweeps
Region is retouched, the scanning area is opposite with the inner membrance item.
Wherein, be additionally provided at least one second reaction cup on the detection card ontology, second reaction cup it is small in size
In the volume of first reaction cup.
Wherein, the quantity of first reaction cup is multiple, and the quantity of second reaction cup is multiple；Multiple described
One reaction cup is arranged in rows along the width direction of the detection card ontology；Multiple second reaction cups are along the detection card ontology
Width direction be arranged in rows.
Wherein, the quantity of the film bar groove is multiple, and the quantity of the Test paper is multiple, the number of the film bar cover board
Amount is multiple；Multiple film bar grooves are arranged in rows along the width direction of the detection card ontology；And in each film bar groove
It is placed with Test paper；The film bar cover board is covered on each Test paper.
Wherein, the length of first reaction cup, second reaction cup and the film bar groove along the detection card ontology
Direction is sequentially arranged.
Wherein, the hemofiltration pad is placed on the film bar groove close to one end of second reaction cup；Correspondingly, described to add
Sample hole is provided with the film bar cover board close to one end of second reaction cup.
Wherein, at least one clamping is equipped at the both sides of the edge on the film bar cover board surface opposite with the inner membrance item
Portion.
Wherein, at least one groove is equipped at the film bar cover board surface opposite with the water absorption pad.
Wherein, the well is the bellmouth that the detection card ontology direction is directed toward from the film bar cover board；And it is described
The one end of well far from the film bar cover board is close to the hemofiltration pad.
Wherein, the apparent surface of the detection card ontology is equipped with identification code, and the identification code carries full-automatic detection
Detection project information, expired time information and the calibration curve information of card.
(3) beneficial effect
A kind of automatically detection card provided by the invention, by the way that the first reaction cup and well are all integrated in detection card originally
On one surface of body, and transparent scanning area is equipped on another surface of reagent card ontology, which can be with inner membrance
Detection line and nature controlling line on item are shown, are facilitated detection card to be matched with intelligent analysis instrument, are reduced pollution etc.,
And the mixing of buffer and sample liquid can be completed on detection card, improve the convenience of detection card.
Detailed description of the invention
Fig. 1 is the structural schematic diagram of a preferred embodiment of full-automatic detection card provided by the invention；
Fig. 2 is the bottom substance schematic diagram of full-automatic detection card shown in FIG. 1；
Fig. 3 is the structural schematic diagram of a preferred embodiment of Test paper provided by the invention；
Fig. 4 is the structural schematic diagram of a preferred embodiment of film bar cover board provided by the invention；
In figure, the first reaction cup of 1-；The second reaction cup of 2-；3- well；4- film bar cover board；5- film bar groove；6- identification code；
7- scanning area；8- detection line；9- nature controlling line；10- hemofiltration pad；11- inner membrance item；12- water absorption pad；13- bottom plate；14- card-tight part；
15- groove.
Specific embodiment
With reference to the accompanying drawings and examples, specific embodiments of the present invention will be described in further detail.Following instance
For illustrating the present invention, but it is not intended to limit the scope of the invention.
In the description of the present invention, it is to be understood that, term " center ", " longitudinal direction ", " transverse direction ", " length ", " width ",
" thickness ", "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom" "inner", "outside", " up time
The orientation or positional relationship of the instructions such as needle ", " counterclockwise ", " axial direction ", " radial direction ", " circumferential direction " be orientation based on the figure or
Positional relationship is merely for convenience of description of the present invention and simplification of the description, rather than the device or element of indication or suggestion meaning must
There must be specific orientation, be constructed and operated in a specific orientation, therefore be not considered as limiting the invention.
In addition, term " first ", " second " are used for descriptive purposes only and cannot be understood as indicating or suggesting relative importance
Or implicitly indicate the quantity of indicated technical characteristic.Define " first " as a result, the feature of " second " can be expressed or
Implicitly include at least one this feature.In the description of the present invention, the meaning of " plurality " is at least two, such as two, three
It is a etc., unless otherwise specifically defined.
In the present invention unless specifically defined or limited otherwise, term " installation ", " connected ", " connection ", " fixation " etc.
Term shall be understood in a broad sense, for example, it may be being fixedly connected, may be a detachable connection, or integral；It can be mechanical connect
It connects, is also possible to be electrically connected or can communicate each other；It can be directly connected, can also indirectly connected through an intermediary, it can be with
It is the interaction relationship of the connection or two elements inside two elements, unless otherwise restricted clearly.For this field
For those of ordinary skill, the specific meanings of the above terms in the present invention can be understood according to specific conditions.
Fig. 1 shows a preferred embodiment of full-automatic detection card of the invention, and Fig. 3 shows Test paper of the present invention
One preferred embodiment, as shown in figures 1 and 3, full-automatic detection card (hereinafter referred to as: detection card) include: detection card ontology,
Film bar cover board 4 and at least one Test paper；The surface for detecting card ontology is equipped at least one first reaction cup 1, and
At least one film bar groove 5；First reaction cup 1 is for filling buffer and sample to be tested；Test paper is placed in film bar groove 5；Inspection
Test paper includes the hemofiltration pad 10, inner membrance item 11 and water absorption pad 12 being sequentially connected, and inner membrance item 11 is equipped with detection line 8 and nature controlling line
9；The lid of film bar cover board 4 closes on Test paper, so that Test paper is fastened in film bar groove 5；And on film bar cover board 4 with hemofiltration pad
10 opposite place is equipped with well 3；Another surface for detecting card ontology is equipped with scanning area 7, scanning area 7 and inner membrance item 11
Relatively.
Specifically, for example, detection card ontology and film bar cover board 4 are made of plastics；For example, in a table of detection card ontology
Face is equipped with first reaction cups 1 such as one, two or three, and is equipped with the films bar grooves 5 such as one, two or three；Correspondingly, film
The quantity of bar cover board 4 and Test paper is also one, two or three etc., that is, film bar groove 5, Test paper and film bar cover board 4
Quantity is equal.And first reaction cup 1 and film bar groove 5 can be set in any position of detection card body surface, as long as this first
Reaction cup 1 can be used in filling buffer and sample to be tested, and film bar groove 5 can be used in placing Test paper.And it will test test paper and put
It sets in film bar groove 5, which includes the hemofiltration pad 10, inner membrance item 11 and water absorption pad 12 being sequentially connected, as shown in Figure 3；
For example, the connection relationship of three is contact connectio etc.；And inner membrance item 11 is equipped with detection line 8 (that is, T line) and nature controlling line 9 (that is, C
Line), for example, the length direction of detection line 8 and nature controlling line 9 is parallel with the width direction of inner membrance item 11.
And close the lid of film bar cover board 4 on Test paper, so that film bar cover board 4 and inspection is arranged by card in Test paper
It surveys between card ontology, ensure that the stability of Test paper position, so that Test paper will not move during the test.
And opposite place is equipped with well 3 with hemofiltration pad 10 on film bar cover board 4, for example, the shape of well 3 can be round, ellipse
Round or rectangular etc., as long as that is, sample liquid can be added by the well 3, well 3 be can have any shape.And it is examining
Another surface for surveying card ontology is equipped with scanning area 7, for example, the scanning area 7 is opening or transparent part；I.e. detection blocks this
One surface of body is opposite with another surface, as shown in Figure 2；For example, the shape of scanning area 7 can be set as to ellipse or rectangular
Shape etc., as long as can scan detection line 8 and nature controlling line 9 on inner membrance item 11 by the scanning area 7, which can be with
For arbitrary shape.
When being detected using above-mentioned detection card to sample liquid, first buffer can be added in the first reaction cup 1, then take to
Sample measuring liquid is added in buffer and is mixed；Then, the sample of mixing is taken to be added in well 3 so that sample through well 3 with
Hemofiltration pad 10 contacts, and the suction through water absorption pad 12 is flowed towards at inner membrance item 11, so that sample successively line 8 and Quality Control after testing
Line 9；It, can 8 He of detection line that occurs of the display of scanning area 7 on Scanning Detction card ontology after the chromatography time of sample to be achieved
Nature controlling line 9, and then complete the detection to the sample liquid.
In the present embodiment, by the way that the first reaction cup 1 and well 3 to be all integrated on a surface of detection card ontology,
And transparent scanning area 7 is equipped on another surface of reagent card ontology, which can be with the detection on inner membrance item 11
Line 8 and nature controlling line 9 are shown, detection card is facilitated to be matched with Artificial Intelligence Instrument, reduce pollution, and on detection card
The mixing that buffer and sample liquid can be completed improves the convenience of detection card.
In addition, reaction cup is fixed at and is detected in the matching used analyzer of card, is being used in existing equipment
It needs to clean the reaction cup after detecting a sample in the process；The detection card can have compared with existing equipment
There are multiple first reaction cups, multiple samples can be detected simultaneously in use, without cleaning, improves the convenience of detection
Degree.
Furthermore it is possible to be sealed in the upper surface of detection card with aluminium foil, i.e. aluminium foil is by film bar cover board, well and reaction
Cup is sealed, can be moisture-proof, can also prevent from influencing each other between two neighboring Test paper.
In addition, as shown in figure 3, hemofiltration pad 10, inner membrance item 11 (that is, NC mould) and water absorption pad 12 successively can be sticked to bottom plate 13
On, so that hemofiltration pad 10, inner membrance item 11 and water absorption pad 12 become overall structure, it conveniently will test test paper and be taken in and out film bar groove
5, and integrally-built Test paper is not susceptible to move in use, can guarantee Test paper to a certain extent
Stability.
Further, it detects on card ontology and is additionally provided at least one second reaction cup 2, the volume of the second reaction cup 2 is less than
The volume of first reaction cup 1.
Wherein, buffer refers to the mixed solution being made of weak acid and its salt, weak base and its salt, can be to a certain extent
It offsets, mitigate the influence of additional strong acid or highly basic to solution acid alkalinity, to keep the pH value of solution relatively stable.
The volume of second reaction cup 2 is set as the volume less than the first reaction cup 1, then can be packed into the second reaction cup 2
Less buffer is measured, the buffer being correspondingly equipped in the first reaction cup 1 is relatively more.Then the reaction cup of two kinds of models can
To meet situation different to the demand of buffer in different detection projects.If the detection project needs of sample to be tested is slow
When the amount of fliud flushing is more, buffer can be obtained from first reaction cup 1；Alternatively, if the detection project of sample to be tested needs
When the amount of buffer is less, buffer can be obtained from second reaction cup 2.
Further, the quantity of the first reaction cup 1 is multiple, and the quantity of the second reaction cup 2 is multiple；Multiple first reactions
Cup 1 is arranged in rows along the width direction of detection card ontology；Multiple second reaction cups 2 along detection card ontology width direction at arrangement
It sets.For example, the quantity of the first reaction cup 1 is six, the quantity of the second reaction cup 2 is also six；It can of course phase as needed
The quantity of the first reaction cup 1 and the second reaction cup 2 should be adjusted, it can also be by the quantity of the first reaction cup 1 and the second reaction cup 2
Quantity is set as equal or unequal.And the width direction by the first reaction cup 1 along detection card ontology is arranged in rows, for example, can be with
Six the first reaction cups 1 are arranged in rows the one end in detection card body width direction；Certain this six the first reaction cups 1
The other positions in detection card ontology can be arranged in rows, as long as first reaction cup 1 can be used for filling buffer and to test sample
This.And the width direction by the second reaction cup 2 along detection card ontology is arranged in rows, for example, can be six second by this
Reaction cup 2 is arranged in rows the other end in detection card body width direction, or this six second reactions are arranged in rows
The side of first reaction cup 1, certain this six the second reaction cups 2 can be arranged in rows the other positions in detection card ontology, only
Will second reaction cup 2 can be used for filling buffer and sample to be tested.
Further, the quantity of film bar groove 5 is multiple, the quantity of Test paper be it is multiple, the quantity of film bar cover board 4 is more
It is a；Multiple film bar grooves 5 are arranged in rows along the width direction of detection card ontology；And Test paper is placed in each film bar groove 5；
Film bar cover board 4 is covered on each Test paper.That is, film bar groove 5, film bar cover board 4 are equal with the quantity of Test paper；Example
Such as, the quantity of film bar groove 5 can be set as six, correspondingly, the quantity of film bar cover board 4 and Test paper is six；In addition,
Also the quantity of film bar groove 5 and the quantity of the first reaction cup 1 or the second reaction cup 2 can be set as identical, so that well 3
Quantity is identical as the quantity of the first reaction cup 1 or the second reaction cup 2.And by multiple film bar grooves 5 along the width side of detection card ontology
To being arranged in rows, for example, multiple film bar grooves 5 can be arranged in rows at the middle part of detection card ontology；It can certainly will be multiple
Film bar groove 5 is arranged in rows the side in the first reaction cup 1 or the second reaction cup 2；That is, multiple film bar grooves 5 can be along detection card originally
The width direction of body is arranged in rows in any position.
And Test paper is placed in each film bar groove 5, and film item lid will be covered on each Test paper
Plate 4；Correspondingly, well 3 is offered on each film bar cover board 4；The detection card of such setting can detect multiple samples simultaneously
This, improves the detection efficiency of detection card.Correspondingly, the scanning area 7 detected on another surface of card ontology can be shown
The detection line 8 and nature controlling line 9 of each Test paper, as shown in Figure 2.
Further, the length direction successively cloth of the first reaction cup 1, the second reaction cup 2 and film bar groove 5 along detection card ontology
It sets.For example, the first reaction cup 1 can be arranged in rows to the one end in the width direction of detection card ontology, by the second reaction cup 2
It is arranged in rows in the side of one end of first reaction cup 1 far from detection card ontology, and film bar groove 5 is arranged in rows second
Side of the reaction cup 2 far from the first reaction cup 1, as shown in Figure 1.The first reaction cup 1, the second reaction cup 2 and the film being arranged such
Bar groove 5, so that the structure setting of detection card is more reasonable.
Further, hemofiltration pad 10 is placed on film bar groove 5 close to one end of the second reaction cup 2；Correspondingly, well 3 is opened
Film bar cover board 4 is located at close to one end of the second reaction cup 2.Well 3 is provided with film bar cover board 4 close to the second reaction cup 2
One end, i.e. well 3 will then delay in the first reaction cup 1 or the second reaction cup 2 close to the second reaction cup 2 and the first reaction cup 1
After fliud flushing and the sample solution to be tested mix, more conveniently the sample after mixing can be added to well 3, opposite can reduce sample
Product are added to the conduct of well 3.And well 3 is provided with film bar groove 5 close to one end of the second reaction cup 2, i.e., so that
Hemofiltration pad 10 and well 3 are positioned opposite, after sample is added into well 3, can smoothly flow to hemofiltration pad 10, into
The subsequent detection process of row.
Further, as shown in figure 4, be equipped at the both sides of the edge on the surface opposite with inner membrance item 11 of film bar cover board 4 to
A few card-tight part 14.For example, card-tight part 14 is clamping block, clamping protrusion etc.；For example, the material of the card-tight part 14 is elasticity
Material, for example, the material of card-tight part 14 is rubber material etc..For example, in film bar cover board 4 and the two of the relative position of inner membrance item 11
Card-tight part 14 there are four being all provided at side edge, that is, eight card-tight parts 14 are set altogether on film bar cover board 4；And the card-tight part 14
Length direction along film bar groove 5 is arranged.Film bar cover board 4 can be then clamped in film bar groove 5 by the card-tight part 14, so that film item
Cover board 4 is not susceptible to loosen；If the material of card-tight part 14 is elastic material, the card-tight part 14 is in clamping film bar cover board 4 and film
When gap between bar groove 5, film bar groove 5 will not be scratched, improves the service life of detection card.
Further, at least one groove 15 is equipped at the surface opposite with water absorption pad 12 of film bar cover board 4.For example, this is recessed
The cross-sectional shape of slot 15 is rectangular or taper etc.；For example, there are four being set at the surface opposite with water absorption pad 12 of film bar cover board 4
Groove 15；For example, four grooves 15 are sequentially arranged along the length direction of film bar groove 5.Then due to the presence of the groove 15, favorably
The sample at hemofiltration pad 10 is drawn at water absorption pad 12 in water absorption pad 12, improves the chromatographic flow ability of sample.
Further, well 3 is the bellmouth from 4 direct detection card ontology direction of film bar cover board；And well 3 is separate
One end of film bar cover board 4 is close to hemofiltration pad 10.For example, well 3 is cone or pyramid etc.；For example, well 3 is pyramid
Shape hole, as shown in Figure 1 and Figure 4.It is located at using the well 3 of this kind of structure type so that sample liquid is added to well 3
The sample liquid on top can generate biggish extruding force to the sample liquid for being located at lower part, allow sample liquid smoothly flow into hemofiltration pad
10.And the end by well 3 far from film bar cover board 4 is close to hemofiltration pad 10, so that sample liquid can to the greatest extent can after the outflow of well 3
Being contacted with hemofiltration pad 10 more than energy.
Further, as shown in Fig. 2, the apparent surface of detection card ontology is equipped with identification code 6, identification code 6 is carried entirely
Detection project information, expired time information and the calibration curve information of automatic detection card.That is, identification code 6 is set respectively with well 3
Set opposite two surfaces on detection card ontology.
Wherein, calibration curve refers to using T/C value as the curvilinear equation of variable.
For example, identification code 6 can for two dimensional code etc., be will the identification code 6 can carry detection card detection project information,
Expired time information and calibration curve information, the identification code 6 can be the identification code 6 of any form.And since the identification code 6 is taken
Detection project information with detection card, the then detection project that the detection card can be got by scanning the identification code 6 are believed
Breath；Since identification code 6 carries expired time information, then by scanning the identification code 6 it can be learnt that whether the detection card is expired,
Guarantee that the detection card for detection is to further increase the reliability and accuracy of detection within effective time；And it should
Identification code 6 carries calibration curve information, then can obtain corresponding calibration curve by scanning the identification code 6, improve inspection
The convenience of survey.
The foregoing is merely illustrative of the preferred embodiments of the present invention, is not intended to limit the invention, all in essence of the invention
Within mind and principle, any modification, equivalent replacement, improvement and so on be should all be included in the protection scope of the present invention.
Claims (10)
1. a kind of full-automatic detection card characterized by comprising detection card ontology, film bar cover board and at least one Test paper；
One surface of the detection card ontology is equipped at least one first reaction cup and at least one film bar groove；Described
One reaction cup is for filling buffer and sample to be tested；
The Test paper is placed in the film bar groove；The Test paper include the hemofiltration pad being sequentially connected, inner membrance item and
Water absorption pad, the inner membrance item are equipped with detection line and nature controlling line；
The film cover plate lid is closed on the Test paper, so that the Test paper is fastened in the film bar groove；And institute
State opposite with the hemofiltration pad on film bar cover board locate equipped with well；
Another surface of the detection card ontology is equipped with scanning area, and the scanning area is opposite with the inner membrance item.
2. full-automatic detection card according to claim 1, which is characterized in that be additionally provided at least one on the detection card ontology
A second reaction cup, the volume of second reaction cup are less than the volume of first reaction cup.
3. full-automatic detection card according to claim 2, which is characterized in that the quantity of first reaction cup be it is multiple,
The quantity of second reaction cup is multiple；
Multiple first reaction cups are arranged in rows along the width direction of the detection card ontology；Multiple second reaction cup edges
The width direction of the detection card ontology is arranged in rows.
4. full-automatic detection card according to claim 3, which is characterized in that the quantity of the film bar groove be it is multiple, it is described
The quantity of Test paper be it is multiple, the quantity of the film bar cover board is multiple；
Multiple film bar grooves are arranged in rows along the width direction of the detection card ontology；And it is placed in each film bar groove
There is Test paper；The film bar cover board is covered on each Test paper.
5. full-automatic detection card according to claim 4, which is characterized in that first reaction cup, second reaction
Cup and the film bar groove are sequentially arranged along the length direction of the detection card ontology.
6. full-automatic detection card according to claim 5, which is characterized in that the hemofiltration pad is placed on the film bar groove and leans on
One end of nearly second reaction cup；Correspondingly, the well is provided with the film bar cover board close to second reaction cup
One end.
7. full-automatic detection card according to claim 1, which is characterized in that the film bar cover board is opposite with the inner membrance item
Surface both sides of the edge at be equipped at least one card-tight part.
8. full-automatic detection card according to claim 1, which is characterized in that the film bar cover board is opposite with the water absorption pad
Surface at be equipped at least one groove.
9. full-automatic detection card according to claim 1-8, which is characterized in that the well is from the film
Bar cover board is directed toward the bellmouth in the detection card ontology direction；And the one end of the well far from the film bar cover board is close to institute
State hemofiltration pad.
10. full-automatic detection card according to claim 1-8, which is characterized in that the phase of the detection card ontology
Identification code is equipped with to surface, the identification code carry the detection project information of full-automatic detection card, expired time information and
Calibration curve information.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201811497929.4A CN109580937A (en) | 2018-12-07 | 2018-12-07 | Full-automatic detection card |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201811497929.4A CN109580937A (en) | 2018-12-07 | 2018-12-07 | Full-automatic detection card |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN109580937A true CN109580937A (en) | 2019-04-05 |
Family
ID=65929404
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201811497929.4A Pending CN109580937A (en) | 2018-12-07 | 2018-12-07 | Full-automatic detection card |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN109580937A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112875017A (en) * | 2021-01-25 | 2021-06-01 | 上海快灵生物科技有限公司 | Test paper card box and test paper card |
Citations (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1473565A1 (en) * | 1997-07-16 | 2004-11-03 | Charm Sciences Inc. | A test device and method for detecting the presence of a residue analyte in a sample |
| CN205015346U (en) * | 2015-09-24 | 2016-02-03 | 霍普金斯(北京)医学诊断科技有限公司 | Be applied to infectiousness sample test's device |
| CN105874053A (en) * | 2013-11-12 | 2016-08-17 | 韩国帕克特生物科技有限公司 | Multi-well cuvette provided with integrated reaction and detection means |
| CN106290811A (en) * | 2016-11-17 | 2017-01-04 | 百奥森（江苏）食品安全科技有限公司 | A kind of automatic locking the illicit drugs inspection card of convenient sampling |
| CN206945702U (en) * | 2017-06-30 | 2018-01-30 | 深圳市宝安康生物技术有限公司 | The colloidal gold immune chromatography test card of quick detection sulfa drugs |
| CN207248896U (en) * | 2017-10-23 | 2018-04-17 | 嘉兴朝云帆生物科技有限公司 | Dog c reactive protein time-resolved fluoroimmunoassay chromatographs detection kit |
| CN207601094U (en) * | 2017-12-16 | 2018-07-10 | 艾博（武汉）生物技术有限公司 | Canine distemper virus reagent card |
| US20180272337A1 (en) * | 2017-03-22 | 2018-09-27 | Hangzhou Biotest Biotech Co., Ltd. | Detection Apparatus for Detecting Analyte in a Liquid Sample and Method Thereof |
| CN209471134U (en) * | 2018-12-07 | 2019-10-08 | 武汉纽康度生物科技股份有限公司 | Full-automatic detection card |
-
2018
- 2018-12-07 CN CN201811497929.4A patent/CN109580937A/en active Pending
Patent Citations (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1473565A1 (en) * | 1997-07-16 | 2004-11-03 | Charm Sciences Inc. | A test device and method for detecting the presence of a residue analyte in a sample |
| CN105874053A (en) * | 2013-11-12 | 2016-08-17 | 韩国帕克特生物科技有限公司 | Multi-well cuvette provided with integrated reaction and detection means |
| CN205015346U (en) * | 2015-09-24 | 2016-02-03 | 霍普金斯(北京)医学诊断科技有限公司 | Be applied to infectiousness sample test's device |
| CN106290811A (en) * | 2016-11-17 | 2017-01-04 | 百奥森（江苏）食品安全科技有限公司 | A kind of automatic locking the illicit drugs inspection card of convenient sampling |
| US20180272337A1 (en) * | 2017-03-22 | 2018-09-27 | Hangzhou Biotest Biotech Co., Ltd. | Detection Apparatus for Detecting Analyte in a Liquid Sample and Method Thereof |
| CN206945702U (en) * | 2017-06-30 | 2018-01-30 | 深圳市宝安康生物技术有限公司 | The colloidal gold immune chromatography test card of quick detection sulfa drugs |
| CN207248896U (en) * | 2017-10-23 | 2018-04-17 | 嘉兴朝云帆生物科技有限公司 | Dog c reactive protein time-resolved fluoroimmunoassay chromatographs detection kit |
| CN207601094U (en) * | 2017-12-16 | 2018-07-10 | 艾博（武汉）生物技术有限公司 | Canine distemper virus reagent card |
| CN209471134U (en) * | 2018-12-07 | 2019-10-08 | 武汉纽康度生物科技股份有限公司 | Full-automatic detection card |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112875017A (en) * | 2021-01-25 | 2021-06-01 | 上海快灵生物科技有限公司 | Test paper card box and test paper card |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP6261736B2 (en) | Multiwell cuvette with integrated reaction and detection means | |
| JP6966375B2 (en) | Container carrier for automated analysis system | |
| CN203929621U (en) | Quick Response Code is identified the Biochemical Analyzer of calibrating reagent automatically | |
| JPWO2008044594A1 (en) | Cartridge, residual liquid removal method and automatic analyzer | |
| JPH0432984B2 (en) | ||
| CN109669038A (en) | A kind of portable multi-channel chromatographic apparatus | |
| CN209471134U (en) | Full-automatic detection card | |
| CN110869769B (en) | Test suite, test method and dispensing device | |
| US4259079A (en) | Method and apparatus for electrical separation of molecules | |
| CN109580937A (en) | Full-automatic detection card | |
| KR101190190B1 (en) | Device for measuring reflective absorbance and combined device for reflective absorbance and lateral flow analysis | |
| JPH08506903A (en) | Analytical systems and components | |
| CN108490067B (en) | A kind of quartz crystal detection cell of plug-in installation | |
| CN209559844U (en) | Reagent card | |
| CN109669037A (en) | A kind of Seperated multiple channel chromatographic apparatus | |
| US20050226784A1 (en) | Instruments for forming an immobilized sample on a porous membrane, and methods for quantifying target substances in immobilized samples | |
| CN211741313U (en) | Blood grouping kit | |
| CN204855521U (en) | Detect reagent box is unified to dry -type chemistry more | |
| CN114814192A (en) | Novel immunology detect reagent box | |
| CN207096260U (en) | A kind of multi-joint test paper of fluorescence with shade function | |
| WO2015072718A1 (en) | Multi-well cuvette provided with integrated reaction and detection means | |
| CN215678416U (en) | Multi-channel test strip determination plate compatible with fluorescent microplate reader | |
| CN220104852U (en) | Analytical instrument test cup capable of reducing firing pin | |
| CN201518026U (en) | Lymphocyte human leukocyte antigen B5 solid-phase detecting reagent case | |
| CN219533174U (en) | Sample reaction cup of hemagglutination analyzer |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination |