CN109512503B - Low-temperature plasma ablation system capable of outputting stimulation - Google Patents

Low-temperature plasma ablation system capable of outputting stimulation Download PDF

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Publication number
CN109512503B
CN109512503B CN201710840505.2A CN201710840505A CN109512503B CN 109512503 B CN109512503 B CN 109512503B CN 201710840505 A CN201710840505 A CN 201710840505A CN 109512503 B CN109512503 B CN 109512503B
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stimulation
low
temperature plasma
mcu
control
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CN109512503A (en
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黄雍俊
梁瑶
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Sichuan Jinjiang Electronic Medical Device Technology Co ltd
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Sichuan Jinjiang Electronic Science and Technology Co Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/02Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by cooling, e.g. cryogenic techniques
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00571Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for achieving a particular surgical effect
    • A61B2018/00577Ablation
    • A61B2018/00583Coblation, i.e. ablation using a cold plasma

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  • Health & Medical Sciences (AREA)
  • Surgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Otolaryngology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
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  • Plasma Technology (AREA)

Abstract

The invention discloses a low-temperature plasma ablation system capable of outputting stimulation, which comprises: a low temperature plasma control system and a stimulation system; the low-temperature plasma control system comprises a control MCU, a low-temperature plasma generating device and a low-temperature plasma output port; the control MCU controls the low-temperature plasma generating device to generate an electric energy signal through the driving control signal, and outputs the generated electric energy signal to a target position through a low-temperature plasma output port so as to generate plasmas with preset temperature and quantity at the target position; the stimulation system comprises a stimulation MCU, a stimulation generation device and a stimulation output port; the stimulation MCU generates a preset stimulation output signal by driving the stimulation generating device, outputs the stimulation output signal to a target position through the stimulation output port, and simultaneously can also output the stimulation signal through the low-temperature plasma output port by selecting the stimulation port. The system can screen nerves around a part to be processed and accurately judge different nerve types, so that accidental injury to the nerves is avoided, and the safety of low-temperature plasma ablation is improved.

Description

Low-temperature plasma ablation system capable of outputting stimulation
Technical Field
The invention relates to the technical field of low-temperature plasma ablation, in particular to a low-temperature plasma ablation system capable of outputting stimulation.
Background
The low temperature plasma is the fourth state of matter following the solid, liquid, gaseous state, and when the applied voltage reaches the ignition voltage of the gas, the gas is broken down, creating a mixture of electrons, various ions, atoms, and radicals. Although the electron temperature is high in the discharge process, the heavy particle temperature is low, and the whole system is in a low-temperature state, so that the system is called low-temperature plasma.
In clinic, electric energy is commonly used to excite a medium (Nacl) to generate plasma, molecular bonds are broken by kinetic energy generated by the plasma in a temperature range of 40-70 ℃, and biomolecules are directly decomposed into O2,CO2,N2Waiting for gas, completing vaporization of soft tissue in a minimally invasive way,Ablation, shrinkage, hemostasis and the like.
However, in actual clinical procedures, since the conventional low-temperature plasma technology cannot discriminate nerves around a site to be treated and cannot determine the type of nerve at an action site, there is a possibility that nerves which should not be treated are damaged in clinical procedures and a normal nerve is accidentally injured.
Disclosure of Invention
At least one of the objectives of the present invention is to overcome the above problems in the prior art, and to provide a low-temperature plasma ablation system capable of outputting stimulation, which can discriminate nerves around a to-be-treated part and accurately determine different nerve types, thereby avoiding accidental injury to the nerves and improving the safety of low-temperature plasma ablation.
In order to achieve the above object, the present invention adopts the following aspects.
A low-temperature plasma ablation system with stimulation output, comprising: a low temperature plasma control system and a stimulation system;
the low-temperature plasma control system comprises a control MCU, a low-temperature plasma generating device and a low-temperature plasma output port; the control MCU controls the low-temperature plasma generating device to generate an electric energy signal through the driving control signal, and outputs the generated electric energy signal to a target position through a low-temperature plasma output port so as to generate plasmas with preset temperature and quantity at the target position;
the stimulation system comprises a stimulation MCU, a stimulation generation device and a stimulation output port; the stimulation MCU generates a preset stimulation output signal by driving the stimulation generating device, and outputs the stimulation output signal to a target position through the stimulation output port.
Preferably, a stimulation port selection device is arranged between the low-temperature plasma output port and the stimulation output port, and is used for outputting the stimulation output signal to a target position through the low-temperature plasma output port under the control of the stimulation MCU.
Preferably, the low temperature plasma generating apparatus includes: the control signal isolation transmission controller, the BUCK driving circuit, the BUCK circuit, the high-power switching power supply, the half-bridge driving circuit, the half-bridge amplification control circuit and the low-temperature plasma isolation transformer;
the control MCU respectively inputs a BUCK circuit drive control signal and a half-bridge drive control signal for controlling the generation of low-temperature plasma electric energy into the corresponding BUCK drive circuit and half-bridge drive circuit through the control signal isolation transmission controller, controls the BUCK circuit and the half-bridge amplification control circuit to convert a high-power switching power supply into an electric energy signal for generating low-temperature plasma, and transmits the generated electric energy signal to a low-temperature plasma output port through a low-temperature plasma isolation transformer.
Preferably, the low-temperature plasma control system further comprises a voltage/current detection circuit, an impedance detection circuit and a temperature detection circuit which are connected with the low-temperature plasma output port;
the control MCU is used for monitoring voltage/current, temperature and impedance parameters and adjusting the output electric energy signal according to the monitoring result, thereby controlling the temperature and the quantity of the plasmas generated by the low-temperature plasma generation device.
Preferably, a low-temperature plasma channel switch is further disposed at a low-temperature plasma output port of the low-temperature plasma control system, and is used for turning off output of the electric energy signal according to a control signal of the control MCU.
Preferably, the stimulus generation means includes a DA conversion circuit and an operational amplifier processing circuit; the stimulation MCU is used for driving the DA conversion circuit through the stimulation driving control signal and generating a stimulation output signal with preset amplitude, frequency and pulse width through the operational amplification processing circuit.
Preferably, the stimulation system further comprises a stimulation voltage/circuit detection circuit connected to the stimulation output port, and configured to detect a real-time stimulation output and send a stimulation detection result to the stimulation MCU;
the stimulation MCU is used for monitoring the actual stimulation output signal in real time according to the detection result, and the safety and the reliability of the stimulation signal input to the human body are ensured.
Preferably, the stimulation system further comprises a stimulation channel switch connected to the stimulation output port for turning off the stimulation output according to the control signal of the stimulation MCU.
Preferably, the low-temperature plasma ablation system further comprises a display system respectively connected with the control MCU and the stimulation MCU, and used for displaying the detection information and the system state information and receiving the input information of the human-computer interaction interface through the display MCU.
Preferably, the human-computer interaction interface comprises a foot switch, an alarm circuit, a touch screen, a key and a loudspeaker.
In summary, due to the adoption of the technical scheme, the invention at least has the following beneficial effects:
the stimulation system sends stimulation, outputs stimulation output signals with different frequencies, pulse widths and amplitudes and carries out synchronous monitoring, the plasma control system outputs and controls electric energy to excite low-temperature plasma, the nerves around the part to be processed can be discriminated, different nerve types can be accurately judged, accidental injury to the nerves is avoided, and the safety of low-temperature plasma ablation is improved.
Drawings
Fig. 1 is a schematic structural diagram of a low-temperature plasma ablation system capable of stimulation output according to an embodiment of the invention.
Fig. 2 is a schematic structural diagram of a low-temperature plasma ablation system capable of stimulation output according to another embodiment of the invention.
Fig. 3 is a schematic structural diagram of a low-temperature plasma control system according to an embodiment of the invention.
Fig. 4 is a schematic structural diagram of a stimulation system according to an embodiment of the invention.
Fig. 5 is a schematic structural diagram of a low-temperature plasma ablation system capable of stimulation output according to yet another embodiment of the invention.
Detailed Description
The present invention will be described in further detail with reference to the accompanying drawings and embodiments, so that the objects, technical solutions and advantages of the present invention will be more clearly understood. It should be understood that the specific embodiments described herein are merely illustrative of the invention and are not intended to limit the invention.
As shown in fig. 1, a low temperature plasma ablation system capable of stimulation output according to an embodiment of the present invention includes a low temperature plasma control system and a stimulation system.
The low-temperature plasma control system comprises a control Micro Control Unit (MCU), a low-temperature plasma generating device and a low-temperature plasma output port; the control MCU controls the low-temperature plasma generating device to generate an electric energy signal through the driving control signal, and outputs the generated electric energy signal to a target position through a low-temperature plasma output port so as to generate plasmas with preset temperature and quantity at the target position; the stimulation system comprises a stimulation MCU, a stimulation generation device and a stimulation output port; the stimulation MCU generates a preset stimulation output signal by driving the stimulation generating device, and outputs the stimulation output signal to a target position through the stimulation output port.
As shown in fig. 2, in accordance with another embodiment of the present invention, a stimulation port selection device is further disposed between the low temperature plasma output port and the stimulation output port, and is used to output a stimulation output signal to a target location through the low temperature plasma output port under the control of the stimulation MCU, so that the stimulation output signal can be directly output through the plasma port, or can be output through a separate stimulation port.
Fig. 3 is a schematic structural diagram of a low-temperature plasma control system according to an embodiment of the invention, wherein the low-temperature plasma generating apparatus includes: the control signal isolation transmission controller, the BUCK drive circuit, the BUCK circuit (namely a step-down conversion circuit), the high-power switch power supply, the half-bridge drive circuit, the half-bridge amplification control circuit and the low-temperature plasma isolation transformer; the control MCU respectively inputs a BUCK circuit drive control signal and a half-bridge drive control signal for controlling the generation of low-temperature plasma electric energy into the corresponding BUCK drive circuit and half-bridge drive circuit through the control signal isolation transmission controller, controls the BUCK circuit and the half-bridge amplification control circuit to convert a high-power switching power supply into an electric energy signal for generating low-temperature plasma, and transmits the generated electric energy signal to a low-temperature plasma output port through a low-temperature plasma isolation transformer.
Moreover, the low-temperature plasma control system further comprises a voltage/current detection circuit, an impedance detection circuit and a temperature detection circuit which are connected with the low-temperature plasma output port; the control MCU is used for monitoring voltage/current, temperature and impedance parameters and adjusting the output electric energy signal according to the monitoring result, so that the temperature and the quantity of plasmas generated by the low-temperature plasma generation device are controlled, the output correctness is ensured, and the system safety is improved.
Furthermore, a low-temperature plasma channel switch is further arranged at a low-temperature plasma output port of the low-temperature plasma control system and used for closing the output of the electric energy signal according to the control signal of the control MCU, so that the system safety in standby is ensured.
Fig. 4 is a schematic structural diagram of a stimulation system according to an embodiment of the invention. The stimulation generation device comprises a DA conversion circuit and an operational amplifier processing circuit; the stimulation MCU is used for driving the DA conversion circuit through the stimulation driving control signal and generating a stimulation output signal with preset amplitude, frequency and pulse width through the operational amplification processing circuit.
Also, the stimulation system further includes a stimulation voltage/circuit detection circuit connected to the stimulation output port. The stimulation MCU can control the actually output stimulation pulse square wave signals according to the preset frequency pulse width amplitude control, simultaneously detects the real-time stimulation output through the voltage and current detection circuit, sends the stimulation detection result to the stimulation MCU, and ensures that the stimulation output signals are used for screening the nerves around the part to be processed so as to accurately judge the safety of the stimulation signals in the process of judging different nerve types. Further, the stimulation system also comprises a stimulation channel switch connected with the stimulation output port and used for closing the stimulation output according to the control signal of the stimulation MCU, so that the circuit of the stimulation system is isolated from the outside to prevent unnecessary output.
Fig. 5 is a schematic structural diagram of a low-temperature plasma ablation system capable of stimulation output according to yet another embodiment of the invention. The device further comprises a display system which is respectively connected with the control MCU and the stimulation MCU and is used for displaying detection information and system state information and receiving input information of a human-computer interaction interface through the display MCU. The man-machine interaction interface comprises a foot switch, an alarm circuit, a touch screen, a key and a loudspeaker. The display system monitors and controls the foot switch, the touch liquid crystal screen and the key horn through the display MCU, so that a user can be ensured to have good use experience, and meanwhile, the signal of the system can be well fed back to the user.
The foregoing is merely a detailed description of specific embodiments of the invention and is not intended to limit the invention. Various alterations, modifications and improvements will occur to those skilled in the art without departing from the spirit and scope of the invention.

Claims (9)

1. A cryogenic plasma ablation system with stimulation output, the cryogenic plasma ablation system comprising: a low temperature plasma control system and a stimulation system;
the low-temperature plasma control system comprises a control MCU, a low-temperature plasma generating device and a low-temperature plasma output port; the control MCU controls the low-temperature plasma generating device to generate an electric energy signal through the driving control signal, and outputs the generated electric energy signal to a target position through a low-temperature plasma output port so as to generate plasmas with preset temperature and quantity at the target position;
the stimulation system comprises a stimulation MCU, a stimulation generation device and a stimulation output port; the stimulation MCU generates a preset stimulation output signal by driving the stimulation generating device and outputs the stimulation output signal to a target position through a stimulation output port;
the low-temperature plasma generating apparatus includes: the control signal isolation transmission controller, the BUCK driving circuit, the BUCK circuit, the high-power switching power supply, the half-bridge driving circuit, the half-bridge amplification control circuit and the low-temperature plasma isolation transformer;
the control MCU respectively inputs a BUCK circuit drive control signal and a half-bridge drive control signal for controlling the generation of low-temperature plasma electric energy into the corresponding BUCK drive circuit and half-bridge drive circuit through the control signal isolation transmission controller, controls the BUCK circuit and the half-bridge amplification control circuit to convert a high-power switching power supply into an electric energy signal for generating low-temperature plasma, and transmits the generated electric energy signal to a low-temperature plasma output port through a low-temperature plasma isolation transformer.
2. The system of claim 1, wherein a stimulation port selection device is disposed between the low temperature plasma output port and the stimulation output port for outputting the stimulation output signal to the target location through the low temperature plasma output port under the control of the stimulation MCU.
3. The system of claim 1, wherein the cryogenic plasma control system further comprises a voltage/current detection circuit, an impedance detection circuit, and a temperature detection circuit connected to the cryogenic plasma output port;
the control MCU is used for monitoring voltage/current, temperature and impedance parameters and adjusting the output electric energy signal according to the monitoring result, thereby controlling the temperature and the quantity of the plasmas generated by the low-temperature plasma generation device.
4. The system of claim 3, wherein the low temperature plasma output port of the low temperature plasma control system is further provided with a low temperature plasma channel switch for turning off the output of the power signal according to the control signal of the control MCU.
5. The system of claim 1, wherein the stimulus generation device comprises a DA conversion circuit and an operational amplifier processing circuit; the stimulation MCU is used for driving the DA conversion circuit through the stimulation driving control signal and generating a stimulation output signal with preset amplitude, frequency and pulse width through the operational amplification processing circuit.
6. The system of claim 1, further comprising a stimulation voltage/circuit detection circuit connected to the stimulation output port for detecting the real-time stimulation output and sending the stimulation detection result to the stimulation MCU; the stimulation MCU is used for monitoring the actual stimulation output signal in real time according to the detection result so as to ensure the safety and reliability of the stimulation signal input to the human body.
7. The system of claim 6, further comprising a stimulation channel switch coupled to the stimulation output port for turning off the stimulation output in response to a control signal from the stimulation MCU.
8. The system according to claim 1, further comprising a display system connected to the control MCU and the stimulation MCU, respectively, for displaying the detection information and the system status information, and receiving the input information of the human-machine interaction interface through the display MCU.
9. The system of claim 8, wherein the human-machine interface comprises a foot switch, an alarm circuit, a touch screen, a button, and a speaker.
CN201710840505.2A 2017-09-18 2017-09-18 Low-temperature plasma ablation system capable of outputting stimulation Active CN109512503B (en)

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CN111494001B (en) * 2020-05-12 2021-04-27 北京天星博迈迪医疗器械有限公司 Medical equipment control circuit for generating plasma and plasma medical equipment

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Address after: No. 5, Wuke East 3rd Road, Wuhou District, Chengdu, Sichuan 610000

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Address before: No.5, Wuke East 3rd road, Wuhou Science Park, Chengdu hi tech Industrial Development Zone, Sichuan 610045

Patentee before: SICHUAN JINJIANG ELECTRONIC SCIENCE AND TECHNOLOGY Co.,Ltd.