CN109270261A - A kind of magnetic bead chemiluminescence detection kit - Google Patents
A kind of magnetic bead chemiluminescence detection kit Download PDFInfo
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- CN109270261A CN109270261A CN201811094501.5A CN201811094501A CN109270261A CN 109270261 A CN109270261 A CN 109270261A CN 201811094501 A CN201811094501 A CN 201811094501A CN 109270261 A CN109270261 A CN 109270261A
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- bottle
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
- G01N33/54326—Magnetic particles
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Abstract
The invention discloses a kind of magnetic bead chemiluminescence detection kits, belong to chemiluminescence detection technology field.Its technical solution are as follows: including box body, box cover, reagent bottle, magnetic bead bottle and bracket；The box body includes upper cartridge body and lower box body；The upper cartridge body is not connected to lower box body；The box cover is hinged on upper cartridge body；The lower box body is the drawer that can be pushed and pulled；Liner made of rigid plastics foam is equipped in the upper cartridge body；The liner is equipped with bottle slot；The bottle slot includes magnetic bead bottle slot and multiple reagent bottle slots；The magnetic bead bottle slot size and magnetic bead bottle are adapted, and the reagent bottle slot size and reagent bottle are adapted.The present invention can make rational planning for parking space, facilitate the access of article, store reagent bottle and magnetic bead bottle with security and stability, and can shake up immunomagnetic beads automatically, eliminate the trouble manually shaken up.
Description
Technical field
The present invention relates to chemiluminescence detection technology fields, more particularly to a kind of magnetic bead chemiluminescence detection kit.
Background technique
Existing magnetic bead chemiluminescence detection kit usually has the following problems: 1. are put into reagent bottle and magnetic bead bottle
After in kit, reagent bottle and magnetic bead bottle are frequently not to be fixed in kit, this is resulted in when kit collides, examination
Agent bottle and magnetic bead bottle can shake in kit, or even can collide with the inner wall of kit, lead to reagent bottle and magnetic bead bottle
Or the damage of kit, there are security risks；2. immunomagnetic beads need to be shaken up when in use, it is made to keep suspension
State, and existing kit does not often have a function of shaking up automatically, when use need staff shaken up manually or its
He shakes up churned mechanically mode, brings trouble for detection work.
Summary of the invention
The present invention provides a kind of magnetic bead chemiluminescence detection kit, parking space of making rational planning for facilitates depositing for article
It takes, reagent bottle and magnetic bead bottle can be stored with security and stability, and immunomagnetic beads can be shaken up automatically, eliminate the fiber crops manually shaken up
It is tired.
The technical solution of the present invention is as follows:
A kind of magnetic bead chemiluminescence detection kit, including box body, box cover, reagent bottle, magnetic bead bottle and bracket；The box body includes
Upper cartridge body and lower box body；The upper cartridge body is not connected to lower box body；The box cover is hinged on upper cartridge body；The lower box body is can
The drawer of push-and-pull；Liner made of rigid plastics foam is equipped in the upper cartridge body；The liner is equipped with bottle slot；The bottle slot
Including magnetic bead bottle slot and multiple reagent bottle slots；The magnetic bead bottle slot size and magnetic bead bottle are adapted, the reagent bottle slot size with
Reagent bottle is adapted；Compatible buckle structure is equipped between the reagent bottle and liner and between magnetic bead bottle and liner；
The bracket is equipped with magnetic bead bottle chamber and multiple reagent bottle chambers；Compatible buckle is equipped between the reagent bottle and bracket to tie
Structure；The position-limit mechanism for preventing magnetic bead bottle from moving axially in magnetic bead bottle chamber is equipped between the magnetic bead bottle and bracket；Institute
Magnetic bead bottle lower part is stated equipped with groove；The magnetic bead bottle cavity bottom is equipped with through-hole；After the magnetic bead bottle is put into magnetic bead bottle chamber,
Magnetic bead bottle chamber is stretched out by through-hole in part equipped with groove；The magnetic bead bottle can rotate freely in magnetic bead bottle chamber；It is described
Lower box body is separated into bracket storage area and operational instrument storage area by partition；Foam mat, institute are equipped in the bracket storage area
It states foam mat size and bracket storage area is adapted, the foam mat is equipped with bracket slot.
Preferably, the buckle structure includes spring, insertion section and clamping part；The spring is fixed at the interior of bottle slot
Portion bottom end；The top of the spring is connected with supporting spring, and the supporting spring size and bottle slot are adapted；The left and right two of the magnetic bead bottle
Insertion section is respectively equipped on end and the left and right ends of reagent bottle；After magnetic bead bottle and reagent bottle are put into bottle slot, in the liner
On, position corresponding with insertion section is equipped with clamping part；When pressing magnetic bead bottle or reagent bottle, insertion section can be inserted into or exit folder
Hold portion；Reagent bottle chamber interior bottom end also is provided with spring；The top of the spring is connected with supporting spring, the supporting spring size with
Reagent bottle chamber is adapted；After reagent bottle is put into reagent bottle chamber, on the bracket, position corresponding with insertion section,
Equipped with clamping part.
Preferably, the bottle slot and reagent bottle chamber interior bottom end are all provided with there are two spring.
Preferably, the position-limit mechanism includes the annular projection that magnetic bead bottle upper and lower ends are arranged in, and is arranged in magnetic bead
The rubber annular projection of bottle chamber interior upper and lower ends；After the magnetic bead bottle is put into magnetic bead bottle chamber, the ring of magnetic bead bottle upper end
Shape protrusion abuts against the lower section of the rubber annular projection of magnetic bead bottle chamber upper end, and the annular projection of magnetic bead bottle lower end abuts against magnetic bead
The top of the rubber annular projection of bottle chamber lower end.
Preferably, foam mat is equipped in the bracket storage area, the foam mat size is mutually fitted with bracket storage area
It answers, the foam mat is equipped with bracket slot.
Preferably, compatible locker is equipped between the box cover and upper cartridge body, between upper cartridge body and lower box body.
Preferably, the box cover is equipped with handle.
The invention has the benefit that
1. magnetic bead bottle and reagent bottle fixation are stored in the bottle slot of liner by buckle structure, avoid kit by the present invention
When shaking, the problem of magnetic bead bottle and reagent bottle are moved axially in bottle slot and collided with box cover, magnetic bead bottle and examination ensure that
The safety and stability of agent bottle storage.Meanwhile will test reagent and being stored in reagent bottle and magnetic bead bottle respectively with magnetic bead, it can
It prevents from taking detection reagent and magnetic bead by mistake, facilitates detection.Kit of the invention is additionally provided with bracket, by reagent bottle and magnetic bead bottle point
It is not put into the reagent bottle chamber and magnetic bead bottle chamber of bracket, when being detected, bracket is put in Electrogenerated chemiluminescent immunoassay
In instrument, wherein the groove of magnetic bead bottle lower part is meshed with the transmission item of Electrogenerated chemiluminescent immunoassay instrument, so as to drive magnetic
Pearl bottle is rotated in magnetic bead bottle chamber, plays the role of stirring magnetic bead in magnetic bead bottle, eliminates the fiber crops manually shaken up
It is tired.
2. box body is divided into upper cartridge body and lower box body by the present invention, magnetic bead bottle, reagent bottle and bracket, operational instrument are realized
Separated storage, according to storage article difference kit is divided into different storage areas, rational deployment facilitates examination
Agent, the access of bracket and operational instrument；Meanwhile lower box body being designed as to the drawer that can be pushed and pulled, when accessing bracket and operational instrument
It is more convenient laborsaving.
Detailed description of the invention
Fig. 1 is the structural diagram of the present invention.
Fig. 2 is the structural schematic diagram of buckle structure of the invention.
Fig. 3 is the sectional view of magnetic bead bottle of the invention and magnetic bead bottle chamber.
Fig. 4 is the structural schematic diagram of bracket of the invention.
Description of symbols: 1- box body, 1.1- upper cartridge body, 1.2- lower box body, 2- box cover, 3- reagent bottle, 4- magnetic bead bottle,
4.1- groove, 5- bracket, 6- partition, 7- bracket storage area, 8- operational instrument storage area, 9- liner, 10- bottles of slots, 11- magnetic bead bottle
Chamber, 12- reagent bottle chamber, 13- spring, the insertion section 14-, 15- clamping part, 16- supporting spring, 17- annular projection, 18- rubber ring
Shape protrusion, 19- foam mat, 20- bracket slot, 21- locker.
Specific embodiment
For a better understanding of the present invention, below with specific embodiment come the technical solution that the present invention will be described in detail, still
The present invention is not limited thereto.
As shown in Figs 1-4, the present invention provides a kind of magnetic bead chemiluminescence detection kits, including box body 1, box cover 2, examination
Agent bottle 3, magnetic bead bottle 4 and bracket 5；The box body 1 includes upper cartridge body 1.1 and lower box body 1.2；The upper cartridge body 1.1 and lower box body
1.2 are not connected to；The box cover 2 is hinged on upper cartridge body 1.1；The lower box body 1.2 is the drawer that can be pushed and pulled；The upper cartridge body
Liner 9 made of rigid plastics foam is equipped in 1.1；The liner 9 is equipped with bottle slot 10；The bottle slot 10 includes magnetic bead bottle slot
With multiple reagent bottle slots；The magnetic bead bottle slot size and magnetic bead bottle 4 are adapted, and the reagent bottle slot size is suitable with 3 phase of reagent bottle
It answers；Compatible buckle structure is equipped between the reagent bottle 3 and liner 9 and between magnetic bead bottle 4 and liner 9；The support
Frame 5 is equipped with magnetic bead bottle chamber 11 and multiple reagent bottle chambers 12；Compatible buckle is equipped between the reagent bottle 3 and bracket 5
Structure；The limit for preventing magnetic bead bottle 4 from moving axially in magnetic bead bottle chamber 11 is equipped between the magnetic bead bottle 4 and bracket 5
Mechanism；4 lower part of magnetic bead bottle is equipped with groove 4.1；11 bottom of magnetic bead bottle chamber is equipped with through-hole；The magnetic bead bottle 4 is put into
After in magnetic bead bottle chamber 11, magnetic bead bottle chamber 11 is stretched out by through-hole in the part equipped with groove 4.1；The magnetic bead bottle 4 can be in magnetic
It is rotated freely in pearl bottle chamber 11；The lower box body 1.2 is separated into bracket storage area 7 and operational instrument storage area 8 by partition 6；
Foam mat 19 is equipped in the bracket storage area 7,19 size of foam mat and bracket storage area 7 are adapted, the sea
Silk floss liner 19 is equipped with bracket slot 20.
Wherein, as shown in Fig. 2, the buckle structure includes spring 13, insertion section 14 and clamping part 15；The spring 13 is solid
The inner bottom of bottle slot 10 is set calmly；The top of the spring 13 is connected with supporting spring 16,16 size of supporting spring and bottle slot 10
It is adapted；Insertion section 14 is respectively equipped on the left and right ends of the magnetic bead bottle 4 and the left and right ends of reagent bottle 3；4 He of magnetic bead bottle
After reagent bottle 3 is put into bottle slot 10, on the liner 9, position corresponding with insertion section 14 is equipped with clamping part 15；Pressing
When magnetic bead bottle 4 or reagent bottle 3, insertion section 14 can be inserted into or exit clamping part 15；12 inner bottom of reagent bottle chamber is also set
There is spring 13；The top of the spring 13 is connected with supporting spring 16, and 16 size of supporting spring and reagent bottle chamber 12 are adapted；Reagent
After bottle 3 is put into reagent bottle chamber 12, on the bracket 5, position corresponding with insertion section 14 is equipped with clamping part 15.Institute
It states bottle slot 10 and 12 inner bottom of reagent bottle chamber is all provided with that there are two springs 13, clamping part 15 is made of elastoplastic, such as PE.
As shown in figure 3, the position-limit mechanism includes the annular projection 17 that 4 upper and lower ends of magnetic bead bottle are arranged in, and setting
In the rubber annular projection 18 of 11 inside upper and lower ends of magnetic bead bottle chamber；After the magnetic bead bottle 4 is put into magnetic bead bottle chamber 11, magnetic
The annular projection 17 of 4 upper ends of pearl bottle abuts against the lower section of the rubber annular projection 18 of 11 upper end of magnetic bead bottle chamber, 4 lower end of magnetic bead bottle
Annular projection 17 abut against 11 lower end of magnetic bead bottle chamber rubber annular projection 18 top.
It is explained below with the storage of reagent bottle:
Kit is opened, reagent bottle 3 is put into the reagent bottle slot on liner 9, and make the insertion section of 3 left and right ends of reagent bottle
Clamping part 15 on 14 alignment liners 9.After 3 bottom of reagent bottle touches supporting spring 16, continue press down on reagent bottle 3, force with
Deformation occurs for the connected extruding of spring 13 of supporting spring 16, until 14 stress of insertion section oppresses clamping part 15, clamping part 15 is caused to occur
Deformation causes opening to magnify, and is inserted into insertion section 14 in clamping part 15.Then, reagent bottle 3 is unclamped, at this time reagent bottle slot
The spring 13 of bottom end is in compressive state, and clamping part 15 is caught in insertion section 14, so that reagent bottle 3 is fixed in reagent bottle slot.
When need to take reagent bottle 3 when, only need to press reagent bottle 3, insertion section 14 continues to oppress clamping part 15 downwards so that
Clamping part 15 generates deformation and opening is caused to magnify, and the spring 13 of reagent bottle trench bottom is further compressed.At this point, unclamping reagent bottle
3, spring 13 rebounds, so that 3 stress of reagent bottle is rapidly moving upward, insertion section 14 is exited from the opening of clamping part 15, thus
Complete taking for reagent bottle 3.
It the storage of magnetic bead bottle 4 and takes identical as 3 principle of reagent bottle.
The present invention need to only press lightly on magnetic bead bottle 4 and reagent bottle 3, so that it may by magnetic when storing magnetic bead bottle 4 and reagent bottle 3
Pearl bottle 4 and reagent bottle 3 are fixed in bottle slot 10, and when avoiding kit shaking, magnetic bead bottle 4 and reagent bottle 3 are in 10 inner shaft of bottle slot
To it is mobile and the problem of collide with box cover 2, ensure that the safety and stability that magnetic bead bottle 4 and reagent bottle 3 are stored, simultaneously
Also time saving and energy saving.Bracket 5 is placed on foam mat 19, can prevent bracket 5 from storing in bracket with the vibration of buffer reagent box
It shakes in area 7 and collides with upper cartridge body 1.1 or 1.2 inner wall of lower box body, damage bracket 5 or kit.
When being detected to reagent, as shown in Figures 3 and 4, by reagent bottle 3 and magnetic bead bottle 4 one equipped with tested test agent
It rises and is put into bracket 5.Wherein, the clamping on the spring 13, supporting spring 16, bracket 5 of 12 inner bottom of reagent bottle chamber on bracket 5
Portion 15 also constitutes buckle structure, working principle and above-mentioned buckle structure phase with the insertion section 14 of 3 left and right ends of reagent bottle together
Together, to realize that the fixing on bracket 5 of reagent bottle 3 stores and take.And when being stored in magnetic bead bottle 4 on bracket 5, it needs to use
Power presses magnetic bead bottle 4, until the annular projection 17 of 4 upper and lower ends of magnetic bead bottle all enters in magnetic bead bottle chamber 11, and magnetic bead bottle 4
The annular projection 17 of upper end abuts against the lower section of the rubber annular projection 18 of 11 upper end of magnetic bead bottle chamber, and 4 lower end of magnetic bead bottle
Annular projection 17 then abuts against the top of the rubber annular projection 18 of 11 lower end of magnetic bead bottle chamber, and this makes it possible to prevent magnetic bead bottle
4 in axial direction move in magnetic bead bottle chamber 11.After magnetic bead bottle 4 is put into magnetic bead bottle chamber 11, magnetic bead bottle 4 is equipped with groove
4.1 part magnetic bead bottle chamber 11 is exposed by the through-hole of 11 bottom of magnetic bead bottle chamber.Then, bracket 5 is put in electrochemistry hair
In light immunity analysis instrument, the groove 4.1 of 4 lower part of magnetic bead bottle is meshed with the transmission item of Electrogenerated chemiluminescent immunoassay instrument, drives
Magnetic bead bottle 4 is rotated in magnetic bead bottle chamber 11, to play stirring action to magnetic bead in magnetic bead bottle 4, magnetic bead is made to begin
Eventually in the state to suspend, the trouble manually shaken up is eliminated.
Further, it between the box cover 2 and upper cartridge body 1.1, is equipped between upper cartridge body 1.1 and lower box body 1.2 and mutually fits
The locker 21 matched prevents the article in kit from falling out to be moved easily and carry kit.
Further, the box cover 2 is equipped with handle, is moved easily and carries kit.
Specific embodiments of the present invention are described in detail in conjunction with attached drawing above, but the present invention is not limited to above-mentioned realities
Apply the detail of example, those skilled in the art's modification made within the scope of technical solution of the present invention,
Addition or replacement, also belong to protection scope of the present invention.
It can also be with it is further to note that in the case of no contradiction, between each different embodiment of the invention
Any combination, as long as it does not violate the idea of the present invention, it should also be regarded as the disclosure of the present invention.
Claims (6)
1. a kind of magnetic bead chemiluminescence detection kit, it is characterised in that:
Including box body, box cover, reagent bottle, magnetic bead bottle and bracket；
The box body includes upper cartridge body and lower box body；
The upper cartridge body is not connected to lower box body；
The box cover is hinged on upper cartridge body；
The lower box body is the drawer that can be pushed and pulled；
Liner made of rigid plastics foam is equipped in the upper cartridge body；
The liner is equipped with bottle slot；
The bottle slot includes magnetic bead bottle slot and multiple reagent bottle slots；
The magnetic bead bottle slot size and magnetic bead bottle are adapted, and the reagent bottle slot size and reagent bottle are adapted；
Compatible buckle structure is equipped between the reagent bottle and liner and between magnetic bead bottle and liner；
The bracket is equipped with magnetic bead bottle chamber and multiple reagent bottle chambers；
Compatible buckle structure is equipped between the reagent bottle and bracket；
The position-limit mechanism for preventing magnetic bead bottle from moving axially in magnetic bead bottle chamber is equipped between the magnetic bead bottle and bracket；
The magnetic bead bottle lower part is equipped with groove；
The magnetic bead bottle cavity bottom is equipped with through-hole；
After the magnetic bead bottle is put into magnetic bead bottle chamber, magnetic bead bottle chamber is stretched out by through-hole in the part equipped with groove；
The magnetic bead bottle can rotate freely in magnetic bead bottle chamber；
The lower box body is separated into bracket storage area and operational instrument storage area by partition；
Foam mat is equipped in the bracket storage area, the foam mat size and bracket storage area are adapted, the sponge
Liner is equipped with bracket slot.
2. magnetic bead chemiluminescence detection kit as described in claim 1, it is characterised in that:
The buckle structure includes spring, insertion section and clamping part；
The spring is fixed at the inner bottom of bottle slot；
The top of the spring is connected with supporting spring, and the supporting spring size and bottle slot are adapted；
Insertion section is respectively equipped on the left and right ends of the magnetic bead bottle and the left and right ends of reagent bottle；
After magnetic bead bottle and reagent bottle are put into bottle slot, on the liner, position corresponding with insertion section is equipped with clamping part；
When pressing magnetic bead bottle or reagent bottle, insertion section can be inserted into or exit clamping part；
Reagent bottle chamber interior bottom end also is provided with spring；
The top of the spring is connected with supporting spring, and the supporting spring size and reagent bottle chamber are adapted；
After reagent bottle is put into reagent bottle chamber, on the bracket, position corresponding with insertion section is equipped with clamping part.
3. magnetic bead chemiluminescence detection kit as claimed in claim 2, it is characterised in that: the bottle slot and reagent bottle chamber
Inner bottom is all provided with there are two spring.
4. magnetic bead chemiluminescence detection kit as described in claim 1, it is characterised in that:
The position-limit mechanism includes the annular projection that magnetic bead bottle upper and lower ends are arranged in, and is arranged in magnetic bead bottle chamber interior
The rubber annular projection at lower both ends；
After the magnetic bead bottle is put into magnetic bead bottle chamber, the annular projection of magnetic bead bottle upper end abuts against the rubber of magnetic bead bottle chamber upper end
The lower section of glue annular projection, the annular projection of magnetic bead bottle lower end abut against the upper of the rubber annular projection of magnetic bead bottle chamber lower end
Side.
5. magnetic bead chemiluminescence detection kit as described in claim 1, it is characterised in that: the box cover and upper cartridge body it
Between, compatible locker is equipped between upper cartridge body and lower box body.
6. magnetic bead chemiluminescence detection kit as described in claim 1, it is characterised in that: the box cover is equipped with handle.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201811094501.5A CN109270261A (en) | 2018-09-19 | 2018-09-19 | A kind of magnetic bead chemiluminescence detection kit |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201811094501.5A CN109270261A (en) | 2018-09-19 | 2018-09-19 | A kind of magnetic bead chemiluminescence detection kit |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN109270261A true CN109270261A (en) | 2019-01-25 |
Family
ID=65197604
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201811094501.5A Pending CN109270261A (en) | 2018-09-19 | 2018-09-19 | A kind of magnetic bead chemiluminescence detection kit |
Country Status (1)
| Country | Link |
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| CN (1) | CN109270261A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112843311A (en) * | 2021-01-09 | 2021-05-28 | 杭州赤松光电科技有限公司 | Fragrance atomizing diffusion device convenient to change fragrance liquid container |
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| CN206595185U (en) * | 2017-03-01 | 2017-10-27 | 珠海康晋电气股份有限公司 | A kind of gas-insulated switchgear breaker |
| CN207029916U (en) * | 2017-08-07 | 2018-02-23 | 青岛承恩医疗科技有限公司 | A kind of oral liquid closure |
| CN207745438U (en) * | 2017-12-13 | 2018-08-21 | 陆峰 | Electrical cabinet carbon dioxide temperature-sensitive self-starting extinguishing device |
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| CN112843311B (en) * | 2021-01-09 | 2021-12-21 | 杭州赤松光电科技有限公司 | Fragrance atomizing diffusion device convenient to change fragrance liquid container |
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Application publication date: 20190125 |
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