CN109256213A - A kind of health control method of combination genetic risk and environmental risk factors - Google Patents
A kind of health control method of combination genetic risk and environmental risk factors Download PDFInfo
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- CN109256213A CN109256213A CN201810951413.6A CN201810951413A CN109256213A CN 109256213 A CN109256213 A CN 109256213A CN 201810951413 A CN201810951413 A CN 201810951413A CN 109256213 A CN109256213 A CN 109256213A
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- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
- G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
- G16H50/30—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for calculating health indices; for individual health risk assessment
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- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
- G16H15/00—ICT specially adapted for medical reports, e.g. generation or transmission thereof
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- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
- G16H20/00—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance
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- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
- G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
- G16H50/20—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
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Abstract
The invention discloses the health control methods of a kind of combination genetic risk and environmental risk factors, comprising: following steps: S1: acquiring personal saliva sample sample, and saliva sample sample is sent to genetic test company；S2: obtaining genetic test report, extracts the positive information in the gene mutation result and genetic risk assessment result in genetic test report；S3: personal information data are collected, comprising: individual physiological biochemical factors, lifestyle data, health history data and psychological factor；S4: health model judgement is carried out in conjunction with genetic test report and personal information data；A kind of health control method of more fully individual health information is provided, combine the information data in terms of genetic data, lifestyle data, individual Physiology and biochemistry factor, health history data and the psychological factor of people, based on Risk statistic model foundation health evaluation model, the report of output is with more comprehensive, formation more specific aim and operability health control and health guidance.
Description
Technical field
The invention belongs to health control technical fields, and in particular to a kind of combination genetic risk and environmental risk factors it is strong
Health management method.
Background technique
Health guidance under risk assessment is the important work that recent domestic research promotes national physique and disease preventing and treating
Tool especially has great importance in terms of predictive disease danger and personalized health management and guidance, in information theory research
On the basis of, health risk assessment and guiding software are established, provides important technical support for assessment；At present at home there are no than
More mature is health management system arranged, and compatriots do not know its benefit yet, but will expand in future health risk assessment
And receiving, by for government's especially hygiene and health and governmental administration of sport department improve national health provide aid decision according to
According to；Common disease especially chronic disease includes diabetes, and hypertension, the morbidity of tumour is due to both h and E factors
Influence.
It, can be by acquiring environmental factor relevant to people, lifestyle data, health in terms of environmental impact factor
Information data in terms of history data and psychological factor predict by statistics Risk statistic model the disease wind of the individual
Danger；In genetic aspect, the latest developments of current gene sequencing technology greatly improve the hereditation for these diseases
Understanding in addition genome sequencing technology breakthrough and the universal hereditary variation that can detect individual carrying on a large scale and by
This obtain individual disease risk even and the susceptibility to certain bad life styles height.
Existing health control method is based purely on genetic risk or is based purely on environmental impact factor and obtains, to guidance
Individuation health control is imperfect and defective.
Summary of the invention
To overcome existing health control method to exist to instructing the incomplete technological deficiency of individuation health control, the present invention
Disclose the health control method of a kind of combination genetic risk and environmental risk factors.
The technical solution adopted by the present invention to solve the technical problems is a kind of combination genetic risk and environmental risk factors
Health control method, comprising: following steps:
S1: personal saliva sample sample is acquired, and saliva sample sample is sent to genetic test company；
S2: obtaining genetic test report, extracts in the gene mutation result and genetic risk assessment result in genetic test report
Positive information；
S3: collect personal information data, comprising: individual physiological biochemical factors, lifestyle data, health history data and psychology because
Element；
S4: health model judgement is carried out in conjunction with genetic test report and personal information data；
S5: personalized health management scheme is generated.
Preferably, the collection mode of the personal information data is that questionnaire survey and wearable device are collected.
Preferably, the individual physiological biochemical factors include: gender, age, height, weight and vital sign；Life side
Formula data include: eating habit, sleep habit, work habit and exercise habit.
Preferably, the wearable device is for collecting vital sign, and wearable device includes at least: intelligent health monitoring wrist
Table, intelligent health monitoring bracelet, intelligent health monitoring waistband, intelligent health monitoring mattress, intelligent health monitoring back cushion, intelligence are strong
Health monitoring headrest, intelligent health monitoring waist pillow and human body infrared thermal imaging distribution instrument；
The vital sign includes at least: body temperature, electrocardio, heart rate, blood oxygen, blood pressure, blood glucose, pulse, breathing, body it is dynamic and
Body image space.
Preferably, the specific steps of the health model judgement include:
S11: checking that genetic test is reported, the analysis of biological information of the genetic data according to report offer is as a result, obtain risk etc.
Grade, the risk class includes absolute risk and relative risk；
S12: selecting the high risk and high risk of relative risk >=1.2, finds out high risk and the corresponding risk base of high risk
Cause；
S13: risk genes are classified according to gene function, analyze main effect of the risk genes in disease, minor effect with
And the metabolic pathway in disease；
S14: comparing according to risk genes and personal information data, judges unfavorable environmental factor.
Preferably, saliva sample sample can be learnt by single nucleotide polymorphism (SNP), proteomics or epigenetic
To hereditary information.
The beneficial effects of the present invention are: providing a kind of health control method of more fully individual health information, combine
Information Number in terms of the genetic data of people, lifestyle data, individual Physiology and biochemistry factor, health history data and psychological factor
According to being based on Risk statistic model foundation health evaluation model, the report of output is formed and has more specific aim and can with more comprehensive
Operational health control and health guidance.
Detailed description of the invention
Fig. 1 is the method flow diagram of the health control method of a kind of combination genetic risk of the present invention and environmental risk factors.
Specific embodiment
More detailed description is done to embodiments of the present invention below in conjunction with attached drawing and appended drawing reference, makes to be familiar with this field
Technology people can implement accordingly after studying this specification carefully.It should be appreciated that specific embodiment described herein is only to explain this
Invention, is not intended to limit the present invention.
A kind of health control method of combination genetic risk and environmental risk factors, comprising: following steps:
S1: personal saliva sample sample is acquired, and saliva sample sample is sent to genetic test company；
S2: obtaining genetic test report, extracts in the gene mutation result and genetic risk assessment result in genetic test report
Positive information；
S3: collect personal information data, comprising: individual physiological biochemical factors, lifestyle data, health history data and psychology because
Element；
S4: health model judgement is carried out in conjunction with genetic test report and personal information data；
S5: personalized health management scheme is generated；
Health model judgement is carried out by combining genetic test report and personal information data, acquisition individual physiological biochemical factors,
Information data in terms of lifestyle data, health history data and psychological factor, has been collected simultaneously hereditary information, i.e., by interior
Because of (gene) and external cause (environment) binding analysis disease, accomplished that health and fitness information is comprehensive, healthy scheme according to more comprehensively, more section
It learns, has great importance in predictive disease risk factor and in terms of instructing healthy living two.
The collection mode of the personal information data is that questionnaire survey and wearable device are collected；The individual physiological biochemistry because
Element includes: gender, age, height, weight and vital sign；Lifestyle data includes: eating habit, sleep habit, work
Habit and exercise habit；
The questionnaire survey is used to collect gender, age, height and the weight in individual physiological biochemical factors, life style number
According to health history data and psychological factor；The wearable device is for collecting vital sign.
For collecting vital sign, wearable device includes at least the wearable device: intelligent health monitoring watch, intelligence are strong
Health monitors bracelet, intelligent health monitoring waistband, intelligent health monitoring mattress, intelligent health monitoring back cushion, intelligent health monitoring head
Pillow, intelligent health monitoring waist pillow and human body infrared thermal imaging distribution instrument；
The vital sign includes at least: body temperature, electrocardio, heart rate, blood oxygen, blood pressure, blood glucose, pulse, breathing, body it is dynamic and
Body image space；Specifically, the intelligent health monitoring watch, intelligent health monitoring bracelet and intelligent health monitoring waistband are
Portable wearing acquires body temperature, heart rate, blood oxygen, the information of blood pressure and pulse；Intelligent health monitoring mattress, intelligent health
Back cushion, intelligent health monitoring headrest and intelligent health monitoring waist pillow are monitored for acquiring electrocardio, breathing and body movement information；Human body is red
Outer thermal imaging distribution instrument is for acquiring body effect space.
The specific steps of health model judgement include:
S11: checking that genetic test is reported, the analysis of biological information of the genetic data according to report offer is as a result, obtain risk etc.
Grade, the risk class includes absolute risk and relative risk；
S12: selecting the high risk and high risk of relative risk >=1.2, finds out high risk and the corresponding risk base of high risk
Cause；
S13: risk genes are classified according to gene function, analyze main effect of the risk genes in disease, minor effect with
And the metabolic pathway in disease；
S14: comparing according to risk genes and personal information data, judges unfavorable environmental factor；
Wherein the relative risk in S11 can be obtained by statistics Risk statistic model, for example, Harvard risk of cancer index, is to be based on
The cancer risk assessment model of life style and routine physical examination data, relative risk are prediction Personal and its same Sex, Age
Group general population comparison result, wherein relative risk is formulated to five grades, respectively substantially less than general population, be lower than
General population is equivalent to the general human rights, higher than general population and is significantly higher than general population；
Relative risk >=1.2 are to find higher higher than general population and the high risk and high risk that are significantly higher than general population
Risk and the corresponding risk genes of high risk carry out selective analysis, and risk genes are classified according to gene function, analyze wind
Main effect, minor effect and metabolic pathway in disease of the dangerous gene in disease；Gene function is according to international and domestic ginseng
Document is examined, and constantly goes to confirm from a large amount of crowd's sample sizes in application process；
Such as: ADD1 gene mutation participates in the ion transport of intercellular signal transduction and cell membrane, Na ion, K from
It plays an important role in son, Cl ion transport, which influences expression and na-k-atp enzyme of the albumen on cell membrane
Transport speed, increase the reabsorption of renal tubule sodium ion, cause water, sodium retention, blood volume increases, and vascular smooth muscle is caused to be received
Contracting, increases the onset risk of hypertension, obtain healthy scheme according to above-mentioned, preventive key point: especially sensitive for salt, taste should be clear
It is light, it is related with Renal function in early period damage.
Saliva sample sample can obtain heredity by single nucleotide polymorphism (SNP), proteomics or epigenetics
Information；The single nucleotide polymorphism (SNP) is primarily referred to as caused by a single nucleotide variation at the genomic level
DNA sequence polymorphism；Proteomics is research cell, tissue or organism protein group using protein group as research object
At and its changing rule science；Epigenetics, which then refers to, changes caused gene expression dose variation based on non-genomic sequence.
The above content is combine specific preferred embodiment to the further description of the invention made, and it cannot be said that originally
The specific embodiment of invention is only limited to these instructions.For those of ordinary skill in the art to which the present invention belongs,
The other embodiments obtained in the case where not departing from technical solution of the present invention, should be included within the scope of the present invention.
Claims (6)
1. a kind of health control method of combination genetic risk and environmental risk factors, it is characterised in that: include: following steps:
S1: personal saliva sample sample is acquired, and saliva sample sample is sent to genetic test company；
S2: obtaining genetic test report, extracts in the gene mutation result and genetic risk assessment result in genetic test report
Positive information；
S3: collect personal information data, comprising: individual physiological biochemical factors, lifestyle data, health history data and psychology because
Element；
S4: health model judgement is carried out in conjunction with genetic test report and personal information data；
S5: personalized health management scheme is generated.
2. a kind of health control method of combination genetic risk and environmental risk factors as described in claim 1, feature exist
In: the collection mode of the personal information data is that questionnaire survey and wearable device are collected.
3. a kind of health control method of combination genetic risk and environmental risk factors as described in claim 1, feature exist
In: the individual physiological biochemical factors include: gender, age, height, weight and vital sign；Lifestyle data includes: drink
Dietary habits, sleep habit, work habit and exercise habit.
4. the health control method of a kind of combination genetic risk and environmental risk factors as described in claim 2 and 3, feature
Be: the wearable device is for collecting vital sign, and wearable device includes at least: intelligent health monitoring watch, intelligent health
Monitor bracelet, intelligent health monitoring waistband, intelligent health monitoring mattress, intelligent health monitoring back cushion, intelligent health monitoring headrest,
Intelligent health monitoring waist pillow and human body infrared thermal imaging distribution instrument；
The vital sign includes at least: body temperature, electrocardio, heart rate, blood oxygen, blood pressure, blood glucose, pulse, breathing, body moves and people
Body image space.
5. a kind of health control method of combination genetic risk and environmental risk factors as described in claim 1, feature exist
In: the specific steps of the health model judgement include:
S11: checking that genetic test is reported, the analysis of biological information of the genetic data according to report offer is as a result, obtain risk etc.
Grade, the risk class includes absolute risk and relative risk；
S12: selecting the high risk and high risk of relative risk >=1.2, finds out high risk and the corresponding risk base of high risk
Cause；
S13: risk genes are classified according to gene function, analyze main effect of the risk genes in disease, minor effect with
And the metabolic pathway in disease；
S14: comparing according to risk genes and personal information data, judges unfavorable environmental factor.
6. a kind of health control method of combination genetic risk and environmental risk factors as described in claim 1, feature exist
In: saliva sample sample can obtain hereditary information by single nucleotide polymorphism (SNP), proteomics or epigenetics.
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| CN110808102A (en) * | 2019-11-01 | 2020-02-18 | 广州红腾文化科技有限公司 | Information pushing method, system and terminal of health platform |
| CN111584000A (en) * | 2020-05-07 | 2020-08-25 | 重庆医科大学 | Behavior intervention method based on network fusion gene information feedback |
| CN111653360A (en) * | 2020-05-26 | 2020-09-11 | 苏州罗塞塔生物科技有限公司 | Intervention system based on brain health risk assessment |
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