CN109172937A - A kind of oncology built-in type chemicotherapy pump - Google Patents
A kind of oncology built-in type chemicotherapy pump Download PDFInfo
- Publication number
- CN109172937A CN109172937A CN201811104383.1A CN201811104383A CN109172937A CN 109172937 A CN109172937 A CN 109172937A CN 201811104383 A CN201811104383 A CN 201811104383A CN 109172937 A CN109172937 A CN 109172937A
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- China
- Prior art keywords
- elastic force
- medicine storing
- storing bag
- conduit
- built
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
- A61M5/145—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons
- A61M5/148—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons flexible, e.g. independent bags
- A61M5/152—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons flexible, e.g. independent bags pressurised by contraction of elastic reservoirs
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- Health & Medical Sciences (AREA)
- Vascular Medicine (AREA)
- Engineering & Computer Science (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
Abstract
The present invention relates to a kind of oncology built-in type chemicotherapies to pump, including transfusion port, conduit, elastic force medicine storing bag, the transfusion port is equipped with connector, check valve is equipped in connector, check valve is the prior art, in this application, it repeats no more, connector is connected by locking device with the conduit to match, the transfusion port is connected by check valve with conduit, the conduit includes through duct, two kinds of drug storage conduit, wherein the end of through duct is equipped with the first one-way valve, the end of drug storage conduit is connected with elastic force medicine storing bag, elastic force medicine storing bag is equipped with delivery tube, delivery tube is equipped with the second one-way valve.The present invention is put into the cavity of affected part by embedment implanted chemotherapy pump, elastic force medicine storing bag, and chemotherapeutics is injected in elastic force medicine storing bag, elastic force medicine storing bag is discharged according to flow velocity in vivo, the concentration of chemotherapeutics is kept, the time for retaining high concentration medicine in tumor focus is long, reaches the drug effect of chemotherapy.
Description
Technical field
The present invention relates to tumor chemoradiotherapy technical fields, and in particular to a kind of oncology built-in type chemicotherapy pump.
Background technique
Radiation and chemotherapy plays fragmentation effect in Sensitive Tumor Cells, depends primarily on drug concentration and effective contact
Time, therefore try to make drug in tumor focus part high concentration, for a long time presence as much as possible, it is to improve local treatment effect
The key of fruit.The subcutaneously duplicate progress chemotherapeutics perfusion of embedded chemotherapy pump, can greatly improve local drug concentration,
To further increase the curative effect of Partial tumors.
Now traditional implanted chemotherapy pump, when injecting drug, since pump housing merging can not subcutaneously see puncture diaphragm
Position, the region of micro-judgment injection needle point insertion can only be leaned on, the pump housing made of titanium alloy can in injection needle insertion
Hear metal bump sound, but the pump housing of thermoplastic, it when puncture needle bottoms out, will not make a sound, so being not easy to judge
The depth of injection needle.
Chemotherapeutics is injected chemotherapy pump using infusion pump, sacculus duration chemotherapy pump by the implanted chemotherapy pump after burying
It is interior, tumor focus is imported via conduit, implanted chemotherapy pump does not store the effect of chemotherapeutics, for bladder cancer, uterine cancer
In equal cavitys for mucous membrane cancer, due to the effect by inner membrance juice, the concentration of chemotherapeutics can be reduced, or even with secretion
Liquid stream goes out, and reduces the concentration of its chemotherapeutics, and the time that high concentration medicine retains in tumor focus is short, does not have drug effect,
And the time that drug is contacted with endocardial wall is short, and the drug effect of chemotherapy is not achieved.
Summary of the invention
To overcome the deficiency, the purpose of the present invention is to provide a kind of oncology built-in type chemicotherapies to pump.
The technical solution adopted by the present invention to solve the technical problems is: a kind of oncology built-in type chemicotherapy pump, packet
Transfusion port, conduit, elastic force medicine storing bag are included, the transfusion port is equipped with connector, is equipped with check valve in connector, check valve is existing
There is technology, in this application, repeat no more, connector is connected by locking device with the conduit to match, the transfusion port
It is connected by check valve with conduit, the conduit includes two kinds of through duct, drug storage conduit, and wherein the end of through duct is set
There is the first one-way valve, the end of drug storage conduit is connected with elastic force medicine storing bag, and elastic force medicine storing bag is equipped with delivery tube, delivery tube
It is equipped with the second one-way valve.
Specifically, the transfusion port includes pedestal, lid, punctures diaphragm, the upper opening for puncturing diaphragm and being located at pedestal
Place punctures diaphragm and is equipped with lid, and lid is fixed on the base diaphragm is punctured, and connector is located at the side of pedestal, single
It is located in connector to valve, the puncture diaphragm, pedestal form a pump chamber between check valve, set in pedestal close to bottom
There is puncture test film.
Specifically, the elastic force medicine storing bag is equipped with the first hard connecting tube, the second hard connecting tube, the connection of the first hard
Pipe is connected by locking device with one end that hose is administered, and the other end that hose is administered is fixed with plugging cap, the connection of the second hard
Pipe is connected by locking device with the end of drug storage conduit.
Specifically, grid-shaped metal mesh bag is equipped on the outside of the elastic force medicine storing bag, volume is greater than bullet after the expansion of metal mesh bag
The maximum drug storage amount volume of power medicine storing bag, the both ends of metal mesh bag are separately fixed at the first hard connecting tube and connect with the second hard
Guan Shang.
Specifically, the grid-shaped metal mesh bag is netted using diamond-mesh or spherical netted or single rotation.
Specifically, the not used elastic force medicine storing bag is externally provided with encapsulated layer, and elastic force medicine storing bag is encapsulated in vacuum state
In encapsulated layer, the elastic force medicine storing bag with metal mesh bag, metal mesh bag compresses post package with elastic force medicine storing bag 6 in encapsulated layer together
It is interior, encapsulated layer using birdsing of the same feather flock together esters biodegradated polymer materal, it is described as collagen, 6-caprolactone (PCL), polylactic acid (PLA),
In polyglycolide (PGA), poly (lactide-co-glycolide) (PLGA), polyacrylamide and Polyhydroxybutyrate (PHB)
It is one or more.
The invention has the following advantages: chemotherapeutics is injected elastic force medicine storing bag by embedment implanted chemotherapy pump
Interior, elastic force medicine storing bag is discharged according to flow velocity in vivo, is kept the concentration of chemotherapeutics, is protected high concentration medicine in tumor focus
The time stayed is long, effectively contacts with mucous membrane inner wall, and useful effect reaches the drug effect of chemotherapy on the mucous membrane for suffering from tumour.
Detailed description of the invention
Fig. 1 is the structural schematic diagram of the embodiment of the present invention one.
Fig. 2 is the structural schematic diagram of the transfusion port of the embodiment of the present invention one.
Fig. 3 is the structural schematic diagram of the embodiment of the present invention two.
Fig. 4 is the elastic force medicine storing bag structural schematic diagram of the embodiment of the present invention three.
Fig. 5 is the elastic force medicine storing bag structural schematic diagram with encapsulated layer when the present invention is not used.
1 transfusion port in figure, 11 pedestals, 12 lids, 13 puncture diaphragm, and 14 pump chambers, 15 puncture test film, 2 check valves, 3 locks
Tight device, 41 through ducts, 42 drug storage conduits, 5 first one-way valves, 6 elastic force medicine storing bags, 61 first hard connecting tubes, 62 give
Medicine hose, 63 second one-way valves, 64 second hard connecting tubes, 7 metal mesh bags, 8 encapsulated layers.
Specific embodiment
In conjunction with the accompanying drawings, the present invention is further explained in detail.
Embodiment one
A kind of oncology built-in type chemicotherapy pump according to shown in Fig. 1,2, including transfusion port 1, conduit, the transfusion port
1 is equipped with connector 2, is equipped with check valve in connector 2, and check valve is the prior art, in this application, is repeated no more, and is connected
First 2 are connected by locking device 3 with the conduit to match, and the transfusion port 1 is connected by check valve with conduit, described to lead
Pipe is set as through duct 41, and the end of through duct 41 is equipped with the first one-way valve 5.
Specifically, the transfusion port 1 includes pedestal 11, lid 12, punctures diaphragm 13, and the puncture diaphragm 13 is located at pedestal
At 11 upper opening, punctures diaphragm 13 and be equipped with lid 12, lid 12 will puncture diaphragm 13 and fix on the pedestal 11, connector 2
It is located at the side of pedestal 11, check valve is located in connector 2, and the puncture diaphragm 13, pedestal 11 are formed between check valve
One pump chamber is equipped in pedestal 11 close to bottom and punctures test film 15, after puncture needle, which passes through, punctures diaphragm 13, then is pierced into and wears
It pierces in test film 15, in this way in puncture process, is passed through when puncturing diaphragm 13 for the first time and have resistance sense, after puncture, had and fall
Sky sense, wait through puncture test film 15 when, can have resistance sense again, at this moment, can the slightly withdraw of the needle, after exiting, have the sense that falls through,
The end of puncture needle is just puncturing diaphragm 13 and is puncturing in the space between test film 15 in this way, guarantees the syringe needle position of puncture needle
The leakproofness and safety that influence pedestal are repeatedly punctured in also can be avoided in pump chamber.
Embodiment two
A kind of oncology according to Fig.3, is pumped with built-in type chemicotherapy, including transfusion port 1, conduit, elastic force medicine storing bag 6,
The transfusion port 1 is equipped with connector 2, is equipped with check valve in connector 2, check valve is the prior art, in this application, no longer
It repeats, connector 2 is connected by locking device 3 with the conduit to match, and the transfusion port 1 is connected by check valve with conduit
Logical, the conduit is set as drug storage conduit, and the end of drug storage conduit 42 is connected with elastic force medicine storing bag 6, and elastic force medicine storing bag 6 is equipped with
Delivery tube 62, delivery tube 62 are equipped with the second one-way valve 63, elastic force medicine storing bag material and the at present material one of production elasticity pump
Sample selects elastic membrane to be made.
Specifically, the transfusion port 1 includes pedestal 11, lid 12, punctures diaphragm 13, and the puncture diaphragm 13 is located at pedestal
At 11 upper opening, punctures diaphragm 13 and be equipped with lid 12, lid 12 will puncture diaphragm 13 and fix on the pedestal 11, connector 2
It is located at the side of pedestal 11, check valve is located in connector 2, and the puncture diaphragm 13, pedestal 11 are formed between check valve
One pump chamber is equipped in pedestal 11 close to bottom and punctures test film 15, after puncture needle, which passes through, punctures diaphragm 13, then is pierced into and wears
It pierces in test film 15, in this way in puncture process, is passed through when puncturing diaphragm 13 for the first time and have resistance sense, after puncture, had and fall
Sky sense, wait through puncture test film 15 when, can have resistance sense again, at this moment, can the slightly withdraw of the needle, after exiting, have the sense that falls through,
The end of puncture needle is just puncturing diaphragm 13 and is puncturing in the space between test film 15 in this way, guarantees the syringe needle position of puncture needle
The leakproofness and safety that influence pedestal are repeatedly punctured in also can be avoided in pump chamber.
Specifically, the elastic force medicine storing bag 6 is equipped with the first hard connecting tube 61, the second hard connecting tube 64, and first is hard
Matter connecting tube 61 is connected by locking device with one end that hose 62 is administered, and the other end of administration hose 62 is fixed with plugging cap,
Second hard connecting tube 64 is connected by locking device with the end of drug storage conduit 42.
Embodiment three
A kind of oncology built-in type chemicotherapy pump according to shown in Fig. 4,5, including transfusion port 1, conduit, elastic force medicine storing bag
6, the transfusion port 1 is equipped with connector 2, is equipped with check valve in connector 2, check valve is the prior art, in this application, no
It repeats again, connector 2 is connected by locking device 3 with the conduit to match, and the transfusion port 1 passes through check valve and conduit phase
Connection, the conduit are set as drug storage conduit 42, and the end of drug storage conduit 42 is connected with elastic force medicine storing bag 6, on elastic force medicine storing bag 6
Equipped with delivery tube 62, delivery tube 62 is equipped with the second one-way valve 63.
Specifically, the elastic force medicine storing bag 6 is equipped with the first hard connecting tube 61, the second hard connecting tube 64, and first is hard
Matter connecting tube 61 is connected by locking device with one end that hose 62 is administered, and the other end of administration hose 62 is fixed with plugging cap,
Second hard connecting tube 64 is connected by locking device with the end of drug storage conduit 42.
Specifically, grid-shaped metal mesh bag 7 is equipped on the outside of the elastic force medicine storing bag 6, volume is greater than after metal mesh bag 7 is unfolded
The maximum drug storage amount volume of elastic force medicine storing bag 6, it is hard that the both ends of metal mesh bag 7 are separately fixed at the first hard connecting tube 61 and second
In matter connecting tube 64, metal mesh bag 7 can bounce under the action of own resilient, and the work of support protection is played for elastic force medicine storing bag 6
With can support a space for elastic force medicine storing bag 6, prevent elastic force medicine storing bag 6 from thoroughly blocking lumen in lumen.
Specifically, the grid-shaped metal mesh bag 7 is netted using diamond-mesh or spherical netted or single rotation.
Specifically, the not used elastic force medicine storing bag 6 is externally provided with encapsulated layer 8, and elastic force medicine storing bag 6 is encapsulated with vacuum state
In encapsulated layer 8, the elastic force medicine storing bag 6 with metal mesh bag 7, metal mesh bag 7 compresses post package with elastic force medicine storing bag 6 together and exists
In encapsulated layer 8, encapsulated layer 8 is described such as collagen, 6-caprolactone (PCL), poly- cream using esters biodegradated polymer materal of birdsing of the same feather flock together
Sour (PLA), polyglycolide (PGA), poly (lactide-co-glycolide) (PLGA), polyacrylamide and Polyhydroxybutyrate
(PHB) etc., it thus is avoided that damage elastic force medicine storing bag during merging, guarantees that elastic force medicine storing bag is in germ-free condition, wait perform the operation
After the completion, in vivo under liquid effects, encapsulated layer 8 is hydrolyzed, these substances are the biomaterial of approved drug delivery device,
Degraded macromolecular when in use, can be hydrolyzed constantly, be broken into monomeric small molecule, make the elastic force medicine storing bag 6 of package in service portion
Position release, then again by 1 injection of medicine of transfusion port, drug enters in reservoir 6 through liquid storage conduit 42,6 self-constriction of reservoir
Under effect, liquid is discharged through delivery tube.
The present invention is not limited to the embodiment, anyone should learn that the structure made under the inspiration of the present invention becomes
Change, the technical schemes that are same or similar to the present invention are fallen within the scope of protection of the present invention.
Technology not described in detail in the present invention, shape, construction portion are well-known technique.
Claims (8)
1. a kind of oncology is pumped with built-in type chemicotherapy, including transfusion port, conduit, elastic force medicine storing bag, the transfusion port are equipped with
Connector, connector is interior to be equipped with check valve, it is characterised in that: the connector is connected by locking device with the conduit to match
It connects, the transfusion port is connected by check valve with conduit, and the conduit includes two kinds of through duct, drug storage conduit, wherein directly
The end of admittance pipe is equipped with the first one-way valve, and the end of drug storage conduit is connected with elastic force medicine storing bag, sets on elastic force medicine storing bag
There is delivery tube, delivery tube is equipped with the second one-way valve.
2. a kind of oncology according to claim 1 is pumped with built-in type chemicotherapy, it is characterised in that: the transfusion port includes
Pedestal, punctures diaphragm at lid, and the puncture diaphragm is located at the upper opening of pedestal, punctures diaphragm and is equipped with lid, lid will be worn
Thorn diaphragm is fixed on the base, and connector is located at the side of pedestal, and check valve is located in connector, the puncture diaphragm,
A pump chamber is formd between pedestal, check valve, is equipped in pedestal close to bottom and is punctured test film.
3. a kind of oncology according to claim 1 is pumped with built-in type chemicotherapy, it is characterised in that: the elastic force medicine storing bag
It is equipped with the first hard connecting tube, the second hard connecting tube, the first hard connecting tube passes through locking device and the one of administration hose
End is connected, and the other end that hose is administered is fixed with plugging cap, and the second hard connecting tube passes through the end of locking device and drug storage conduit
Portion is connected.
4. a kind of oncology according to claim 1 or 3 is pumped with built-in type chemicotherapy, it is characterised in that: the elastic force storage
Grid-shaped metal mesh bag is equipped on the outside of anther sac, volume is greater than the maximum drug storage amount volume of elastic force medicine storing bag after the expansion of metal mesh bag,
The both ends of metal mesh bag are separately fixed in the first hard connecting tube and the second hard connecting tube.
5. a kind of oncology according to claim 4 is pumped with built-in type chemicotherapy, it is characterised in that: the grid-shaped metal
Mesh bag is netted using diamond-mesh or spherical netted or single rotation.
6. a kind of oncology according to claim 4 is pumped with built-in type chemicotherapy, it is characterised in that: the not used bullet
Power medicine storing bag is externally provided with encapsulated layer, and elastic force medicine storing bag is encapsulated in encapsulated layer with vacuum state.
7. a kind of oncology according to claim 4 is pumped with built-in type chemicotherapy, it is characterised in that: outside is equipped with metal mesh
The elastic force medicine storing bag of bag, metal mesh bag compress post package in encapsulated layer together with elastic force medicine storing bag.
8. a kind of oncology according to claim 6 or 7 is pumped with built-in type chemicotherapy, it is characterised in that: the encapsulated layer
It is described such as collagen, 6-caprolactone (PCL), polylactic acid (PLA), polyglycolide using esters biodegradated polymer materal of birdsing of the same feather flock together
(PGA), one of poly (lactide-co-glycolide) (PLGA), polyacrylamide and Polyhydroxybutyrate (PHB) or more
Kind.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201811104383.1A CN109172937A (en) | 2018-09-21 | 2018-09-21 | A kind of oncology built-in type chemicotherapy pump |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201811104383.1A CN109172937A (en) | 2018-09-21 | 2018-09-21 | A kind of oncology built-in type chemicotherapy pump |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN109172937A true CN109172937A (en) | 2019-01-11 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201811104383.1A Pending CN109172937A (en) | 2018-09-21 | 2018-09-21 | A kind of oncology built-in type chemicotherapy pump |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN109172937A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113456928A (en) * | 2021-07-08 | 2021-10-01 | 广州友沃医疗设备有限公司 | Push type high-pressure syringe |
| CN115089807A (en) * | 2022-06-22 | 2022-09-23 | 上海力声特医学科技有限公司 | Implantable drug delivery system |
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| CN201710803U (en) * | 2010-06-07 | 2011-01-19 | 赵晓云 | Implanted drug delivery device |
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Application publication date: 20190111 |