CN109124608A - Intravascular pressure with developing ring measures conduit - Google Patents
Intravascular pressure with developing ring measures conduit Download PDFInfo
- Publication number
- CN109124608A CN109124608A CN201811304678.3A CN201811304678A CN109124608A CN 109124608 A CN109124608 A CN 109124608A CN 201811304678 A CN201811304678 A CN 201811304678A CN 109124608 A CN109124608 A CN 109124608A
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- China
- Prior art keywords
- pressure
- developing ring
- distal cannula
- conduit
- pressure sensor
- Prior art date
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
- A61B5/021—Measuring pressure in heart or blood vessels
- A61B5/0215—Measuring pressure in heart or blood vessels by means inserted into the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
- A61B5/021—Measuring pressure in heart or blood vessels
- A61B5/02141—Details of apparatus construction, e.g. pump units or housings therefor, cuff pressurising systems, arrangements of fluid conduits or circuits
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
- A61B5/6846—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive
- A61B5/6847—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive mounted on an invasive device
- A61B5/6852—Catheters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B2562/00—Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
- A61B2562/02—Details of sensors specially adapted for in-vivo measurements
- A61B2562/0247—Pressure sensors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M2025/0001—Catheters; Hollow probes for pressure measurement
- A61M2025/0002—Catheters; Hollow probes for pressure measurement with a pressure sensor at the distal end
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M2025/0008—Catheters; Hollow probes having visible markings on its surface, i.e. visible to the naked eye, for any purpose, e.g. insertion depth markers, rotational markers or identification of type
Abstract
The present invention provides a kind of, and the intravascular pressure with developing ring measures conduit, comprising: distal cannula has the guidewire lumen slideably received within individual medical guiding wire；Developing ring, is set to the front end of the distal cannula, and the developing ring has stage portion；Pressure sensor is arranged in the stage portion of the developing ring, for measuring endovascular blood pressure and generating blood pressure signal；And proximal part, couple with the distal cannula, and including the signal path for transmitting the blood pressure signal from the pressure sensor and be used to support the signal path and move the connecting conduit of the distal cannula.In the present invention, the position of pressure sensor can be accurately located.Additionally it is possible to inhibit the adverse effect of distal cannula or proximal part when moving in the blood vessels to pressure sensor measurement, the accuracy of measurement or precision of intravascular pressure measurement conduit are improved.
Description
The application isOn October 21st, 2017, application No. is201710987577.X, it is entitledBand is aobvious The intravascular pressure of shadow ring measures conduitPatent application divisional application.
Technical field
The present invention relates to a kind of, and the intravascular pressure with developing ring measures conduit.
Background technique
For many cardiovascular diseases such as coronary heart disease, percutaneous coronary intervention (pci) (PCI) is relatively effective at present
Treatment means.In recent years, in order to more accurately judge whether patient really needs implementation interventional therapy, assessment stenotic lesion is used
The blood flow reserve score (Fractional Flow Reverse, abbreviation FFR) that obstruction blood flows through the degree of blood vessel increasingly obtains
To application and promote.FFR is defined as the ratio of maximum blood flow and normal maximum blood flow in artery stenosis.It is intravascular in order to calculate
The FFR for giving narrow (being possible to place the position of intravascular stent), needs to measure and acquire respectively narrow distal side (example
Such as, narrow downstream) and narrow proximal lateral (such as narrow upstream, close to aorta) blood pressure readings.Clinical research table
Bright, narrowness is higher, and FFR value is lower, and whether FFR value, which is less than assessed value (such as 0.8), can be used as useful judgment criteria,
It can determine whether interventional therapy is implemented to such patient based on standard doctor.The validity of the judgment criteria has also obtained
To the confirmation of American-European multiple large-scale clinical study results (such as FAME clinical research).
Currently, also having in recent years as the method for measuring intravascular blood pressure using with fast exchange (rapid
Exchange, RX) mouth pressure-sensing conduit.In such pressure-sensing conduit, distal portions, which have, connects seal wire
Inner cavity, by the way that the distal portions are set on seal wire, it is possible thereby to be moved to pressure-sensing conduit along the seal wire predetermined
Position.Before carrying out calcification score, pressure-sensing conduit is passed through into narrow distal side and proximal lateral, records distal end blood respectively
Pressure and proximal end blood pressure.Thereby, it is possible to calculate narrow FFR value.
For existing pressure-sensing conduit, for the ease of positioning the position of conduit, it will usually in the distal end of conduit or close
Developing material is arranged in end part, however, in the prior art, the position of developing material tends not to the position with pressure sensor
Match, therefore, doctor is more difficult in operation to be accurately positioned according to the position of developing material to the position of pressure-sensing, by
There are certain deviations for the narrow distal end blood pressure and proximal end blood pressure that this record obtains, to influence the accurate of the FFR value of measurement
Degree or precision.
Summary of the invention
The present invention in view of the above-mentioned prior art situation and complete, what its purpose is to provide a kind of convenient for positioning can
The intravascular pressure of the accuracy of measurement or precision that improve pressure-sensing conduit measures conduit.
For this purpose, an aspect of of the present present invention provides a kind of intravascular pressure measurement conduit with developing ring, which is characterized in that
Include: distal cannula, there is the guidewire lumen slideably received within individual medical guiding wire；Developing ring is set to described
The front end of distal cannula；Pressure sensor is arranged on the developing ring, for measuring endovascular blood pressure and generating blood pressure
Signal；And proximal part, couple with the distal cannula, and including for transmitting the institute from the pressure sensor
It states the signal path of blood pressure signal and is used to support the connecting conduit of the signal path and the mobile distal cannula.
In addition, another aspect provides a kind of, the intravascular pressure with developing ring measures conduit, and feature exists
In, comprising: distal cannula has the guidewire lumen slideably received within individual medical guiding wire；Proximal part, and it is described
Distal cannula connection；Developing ring is set to the proximal part；And pressure sensor, it is arranged on the developing ring,
For measuring endovascular blood pressure and generating blood pressure signal；Wherein, the proximal part includes coming from the pressure for transmitting
The signal path of the blood pressure signal of sensor and the company for being used to support the signal path and the mobile distal cannula
Connect conduit.
In the present invention, the position of pressure sensor is set on developing ring, in this case, where developing ring
Position is the position of pressure sensor.Therefore, doctor passes through developing ring with can be convenient when carrying out intervention surgical procedure
Position determines the position of pressure sensor, and thereby, it is possible to the position of more accurate positioning pressure sensing.Further, since will
Pressure sensor is arranged on developing ring, therefore buffer function can be brought to pressure sensor, thus is also able to suppress distal end
To the adverse effect of pressure sensor measurement when casing or proximal part move in the blood vessels, improves intravascular pressure and measure conduit
Accuracy of measurement or precision.
In addition, optionally, the developing ring includes opaque to X-ray in measurement conduit according to the present invention
Material.Doctor can determine developing ring and pressure sensing by the methods of X light irradiation in operative process as a result,
The accurate location of device.
In addition, in measurement conduit according to the present invention, optionally, the distal cannula and the proximal part via
Protection pipe connection.Thereby, it is possible to the good connection of distal cannula and proximal part is realized by protection pipe.
In addition, optionally, the pressure sensor includes sensing part and draws in measurement conduit according to the present invention
Line part, the sensing part have the sensing area of sensing pressure, the blood pressure that the lead portion will be generated by the sensing area
Signal export.The blood pressure signal that sensing part generates as a result, can be exported via lead portion, such as be exported to by external equipment
It receives, to realize real-time reading and the record of blood pressure signal.
In addition, in measurement conduit according to the present invention, optionally, the sensing part of the pressure sensor with
There are gaps for the developing ring.In this case, even if developing ring is squeezed in the blood vessels or when deformation occurs, also can
Effectively inhibit the adverse effect to the special sensing part of pressure sensor.
In addition, optionally, the Young's modulus of the developing ring is greater than described remote in measurement conduit according to the present invention
The Young's modulus of end cap pipe.That is, the rigidity (or hardness) of developing ring is greater than the rigidity (or hardness) of distal cannula.It is as a result,
Make in the case where distal cannula bends or is squeezed equal, developing ring is also less likely to occur deformation, to effectively inhibit
To the adverse effect of pressure sensor when distal cannula bends or is squeezed, thus, it is possible to further increase pressure sensing
The measurement accuracy of device.
In addition, optionally, the Young's modulus of the developing ring is greater than described in measurement conduit according to the present invention
The Young's modulus of proximal part.That is, the rigidity (or hardness) of developing ring is greater than the rigidity (or hardness) of proximal part.As a result,
Even if developing ring is also less likely to occur deformation, to effectively press down in the case where proximal part bends or is squeezed equal
To the adverse effect of pressure sensor when proximal part processed bends or is squeezed, thus, it is possible to further increase pressure to pass
The measurement accuracy of sensor.
In addition, optionally, the signal path is at least partially accommodated into institute in measurement conduit according to the present invention
It states in connecting conduit.Thereby, it is possible to so that signal path is effectively protected.
In addition, optionally, the developing ring has stage portion, the pressure in measurement conduit according to the present invention
The lead portion of sensor is fixed on the stage portion, and there are gaps with the stage portion for the sensing part.?
In this case, even if developing ring is squeezed in the blood vessels or when deformation occurs, also can effectively inhibit to pressure sensor
The adverse effect of special sensing part.
In accordance with the invention it is possible to which the band for providing a kind of accuracy of measurement or precision that raising intravascular pressure measures conduit is shown
The intravascular pressure of shadow ring measures conduit.
Detailed description of the invention
Fig. 1 shows the vertical of the intravascular pressure measurement conduit involved in the 1st embodiment of the invention with developing ring
Body structural schematic diagram.
The stereochemical structure of another angle for the intravascular pressure measurement conduit that Fig. 2 shows shown in FIG. 1 with developing ring is shown
It is intended to.
Fig. 3 is to show the intravascular pressure that the embodiment of the 1st invention of the invention is related to measure intubation intervention to people
The schematic diagram of intracorporal cardia.
Fig. 4 shows leading for the intravascular pressure measurement conduit involved in the 1st embodiment of the invention with developing ring
The schematic cross-section of silk inner cavity.
Fig. 5 shows the close of the intravascular pressure measurement conduit involved in the 1st embodiment of the invention with developing ring
The partial sectional schematic view of end part.
Fig. 6 shows the pressure of the intravascular pressure measurement conduit involved in the 1st embodiment of the invention with developing ring
The structural schematic diagram of force snesor and developing ring.
Fig. 7 shows the intravascular pressure measurement conduit involved in the 1st embodiment of the invention with developing ring and passes through
The schematic perspective view of protection pipe connection distal cannula and proximal part.
Fig. 8 shows the vertical of the intravascular pressure measurement conduit involved in the 2nd embodiment of the invention with developing ring
Body structural schematic diagram.
Major Symbol explanation:
1 ... intravascular pressure measures conduit, 2 ... medical guiding wires, 10 ... distal cannulas, 11 ... guidewire lumens, 20 ... proximal ends
Part, 21 ... proximal end outer tubes, 22 ... mandrels, 23 ... conducting wires, 30 ... developing rings, 31 ... stage portions, 40 ... pressure sensors, 41 ...
Sensing part, 42 ... lead portions, 50 ... protection pipes, 51 ... sensing openings, 52 ... guide openings.
Specific embodiment
Hereinafter, explaining the preferred embodiment of the present invention in detail with reference to attached drawing.In the following description, for identical
Component assign identical symbol, the repetitive description thereof will be omitted.Scheme in addition, attached drawing is only schematical, the mutual ruler of component
Very little shape of ratio or component etc. can be with actual difference.
In the following description, the mode of subhead has been used to be described for convenience of explanation, but these subheads
Suggesting effect is only played, is not intended to for content described under subhead being limited in the theme of subhead.
[the 1st embodiment]
Fig. 1 shows the vertical of the intravascular pressure measurement conduit involved in the 1st embodiment of the invention with developing ring
Body structural schematic diagram.The three-dimensional knot of another angle for the intravascular pressure measurement conduit that Fig. 2 shows shown in FIG. 1 with developing ring
Structure schematic diagram.Fig. 3 is to show the intravascular pressure that the embodiment of the 1st invention of the invention is related to measure intubation intervention to people
The schematic diagram of intracorporal cardia.In fig. 1 and 2, as signal, the intravascular pressure measurement conduit 1 with developing ring
Proximal part 20 illustrates only a part close to distal cannula 10.
As depicted in figs. 1 and 2, the intravascular pressure measurement conduit involved in present embodiment with developing ring is (hereinafter, have
When also referred to as " intravascular pressure measurement conduit " or " blood pressure measurement conduit ") 1 may include distal cannula 10 and and distal cannula
The proximal part 20 of 10 connections (or connection).In addition, measurement conduit 1 can also include developing ring 30 and be arranged in developing ring
Pressure sensor 40 on 30.
As described above, pressure sensor 40 is set on developing ring 30.In this case, the position where developing ring 30
The as position of pressure sensor 40, therefore, doctor when carrying out intervention surgical procedure, can be convenient by the position of developing ring
The position to determine pressure sensor is set, thereby, it is possible to the positions of more accurate positioning pressure sensing.Further, since will pressure
Force snesor is arranged on developing ring, therefore buffer function can be brought to pressure sensor, thus is also able to suppress distal end and covers
To the adverse effect of pressure sensor measurement when pipe or proximal part move in the blood vessels, intravascular pressure measurement conduit is improved
Accuracy of measurement or precision.
(distal cannula)
Fig. 3 shows leading for the intravascular pressure measurement conduit involved in the 1st embodiment of the invention with developing ring
The schematic cross-section of silk inner cavity.As shown in figure 3, distal cannula 10 has received medical guiding wire 2, in addition, saving to clearly show that
The diagram of developing ring 30 and pressure sensor 40 involved in such as present embodiment is omited.
In the present embodiment, as shown in figure 3, distal cannula 10 has guidewire lumen 11, guidewire lumen 11 is slideably
Receive individual medical guiding wire 2.In this case, medical guiding wire 2 is received by distal cannula 10, and along medical guiding wire 2
Sliding, so as to which distal cannula 10 and the developing ring being arranged in distal cannula 10 30 and pressure sensor 40 are pushed to disease
The predetermined position of (such as vein, artery) in human body.
In intervention operation, blood pressure measurement conduit 1 can be pushed to patient's body via such as femoral artery or arteria brachialis
It is interior.Specifically, distal portions 10 can connect medical guiding wire 2 (referring to fig. 4), doctor passes through manipulation blood pressure measurement conduit 1
Distal portions 10 can be slided (referring to Fig. 3) toward the direction of arrow A along medical guiding wire 2, and pushed to pre- by proximal part 20
Positioning is set for example close to stenosis for example coronarius, and should using the measurement of pressure sensor 40 being arranged on developing ring 30
The blood pressure of stenosis, such as narrow distal side (for example, narrow downstream, far from aorta) and narrow proximal lateral (such as
Narrow upstream, close to aorta) blood pressure readings.In addition, one end of the separate distal portions 10 of proximal part 20 can be with
The connection such as external external monitoring devices of patient.The blood pressure signal measured by pressure sensor 40 can be sent to monitoring device
Perhaps other processing equipments such as terminal (not shown) monitoring device or other processing equipments can show and store
It is computed the obtained FFR value of blood pressure signal, provides reference for subsequent interventional therapy.
As described above, the value (referred to as " FFR value ") of blood flow reserve score (FFR) can be used to assess stenotic lesion obstruction blood
Liquid stream crosses the degree of blood vessel, and the decision for whether carrying out interventional therapy provided for doctor etc..In general, in order to calculate give it is narrow
FFR value, it is (such as narrow to need to measure and acquire respectively narrow distal side (for example, narrow downstream) and narrow proximal lateral
Narrow upstream, close to aorta) blood pressure readings.The blood pressure gradient of stenotic lesion reflects the instruction of narrow seriousness.It is narrow
Degree is more serious, and pressure drop is bigger, and FFR value is lower.
In addition, in the present embodiment, medical guiding wire 2 is not particularly limited, such as intervention hand can be used in medical guiding wire 2
Common seal wire in art.In some instances, the diameter of medical guiding wire 2 is, for example, 0.2mm~0.7mm, typical or standard doctor
For example there are 0.36mm (0.014 inch), 0.40mm (0.016 inch), 0.64mm (0.025 inch) etc. with the diameter of seal wire 2
Sizes.The medical guiding wire 2 of a variety of different sizes may be incorporated for the survey of intravascular pressure involved in present embodiment as a result,
It measures in conduit 1, doctor etc. selects various sizes of medical guiding wire 2 in which can be convenient, and especially meets the ruler of doctor's use habit
It is very little, consequently facilitating the operation and use of doctor.
In addition, in the present embodiment, the internal diameter of the guidewire lumen 11 of distal cannula 10 can be slightly larger than medical guiding wire 2
Outer diameter.In this case, doctor etc. selects various sizes of medical guiding wire 2 in which can be convenient, as long as can ensure that this is medical
The outer diameter of seal wire 2 is less than the internal diameter of guidewire lumen 11.Thus, on the one hand, can when using such medical guiding wire 2
Facilitate distal cannula 10 to connect medical guiding wire 2, and relatively moves medical guiding wire 2 in the guidewire lumen 11 of distal cannula 10
Or opposite sliding, on the other hand also it is able to suppress the cross-sectional area (the especially cross-sectional area of distal cannula 10) of measurement conduit 1
Increase.
In addition, in the present embodiment, in order to make medical guiding wire 2 move or slide in the guidewire lumen 11 of distal cannula 10
Dynamic, it is preferable to use smooth inner surfaces for guidewire lumen 11.Thus, it is possible to reduce the resistance of stroke process, sufficiently convenient for doctor etc.
It is operated.
In addition, in some instances, the guidewire lumen 11 for receiving medical guiding wire 2 can be only arranged at distal cannula 10.?
That is, guidewire lumen 11 is only limited in distal cannula 10.In this case, due to the guidewire lumen 11 of received medical guiding wire 2
It is only arranged at distal cannula 10, therefore when connecting medical guiding wire 2 in guidewire lumen 11,11 institute of guidewire lumen is received medical
The length of seal wire 2 is than relatively limited, for example, about 5cm~20cm, and therefore, doctor leads via guidewire lumen 11 to medical in which can be convenient
Silk 2 is quickly replaced.
It, as depicted in figs. 1 and 2, can be in addition, in the present embodiment, the shape of distal cannula 10 is not particularly limited
Circular tube shaped substantially in extension of shape.However, present embodiment is without being limited thereto, distal cannula 10 can also involved in present embodiment
With rectangular tubular in extension of shape, oval tubular etc..In addition, in some instances, from easy to process and be conducive in blood vessel
From the viewpoint of interior movement, distal cannula 10 is preferably in elongated tubular.
In addition, in the present embodiment, the length of distal cannula 10 is not particularly limited, as long as ensuring 10 energy of distal cannula
It is enough easily to connect medical guiding wire 2 and medical guiding wire 2 be supported to slide in the guidewire lumen 11 of distal cannula 10.?
In some examples, the length of distal cannula 10 for example may be about 0.5cm~20cm, preferably 5cm~15cm.
In addition, in the present embodiment, as shown in figure 4, the guidewire lumen 11 of distal cannula 10 can have receiving port
11a and guide port 11b.In the present embodiment, as described above, the guidewire lumen 11 of distal cannula 10 can pass through receiving port
11a receives medical guiding wire 2, and medical guiding wire 2 can slide along guidewire lumen 11, and from the guide port 11b quilt of guidewire lumen 11
Export.As a result, measurement conduit 1 can be slided successfully along medical guiding wire 2, distal cannula 10 is navigated into patient's body
Intracorporal specific position (such as affected area).
In addition, in the present embodiment, the receiving port 11a of guidewire lumen 11 can be set distal cannula 10 most before
End, it is possible thereby to easily connect medical guiding wire 2 to distal cannula 10 from receiving port 11a.In addition, the guiding of guidewire lumen 11
Mouth 11b can be set in the side of measurement conduit 1, and in this case, medical guiding wire 2 can be from the reception of guidewire lumen 11
Mouth 11a is slided along guidewire lumen 11 and is drawn from guide port 11b, and thereby, it is possible to inhibit 10 partial cross section of distal cannula product
Increase, to inhibit adverse effect of the sectional area of distal cannula 10 to blood pressure measurement precision.
In addition, in the present embodiment, as shown in Fig. 2, guidewire lumen 11 may include extended segment 111 and with extension
The bending section 112 of 111 connection of section.At this point, extended segment 111 may include above-mentioned receiving port 11a, bending section 112 may include
Above-mentioned guide port 11b.
As shown in figure 4, dotted line L1 and dotted line L2 respectively indicate center line and the bending of the extended segment 111 of distal cannula 10
The center line of section 112.Extended segment 111 is connected to bending section 112 and forms lumen therethrough, it is possible thereby to receive above-mentioned individually medical
Seal wire 2.That is, receiving medical guiding wire 2 by the guidewire lumen 11 for including extended segment 111 and bending section 112, thus cover distal end
Pipe 10 can slide into the predetermined position in patient body (such as affected area) along medical guiding wire 2.
In addition, in the present embodiment, the extended segment 111 of guidewire lumen 11 can be along the length direction of distal cannula 10
Extend.Thereby, it is possible to ensure that extended segment 111 and the moving direction of distal cannula 10 are unanimous on the whole.In addition, guidewire lumen 11
Bending section 112 can be in bending.In this case, it is able to suppress the increase of 10 partial cross section of distal cannula product, to press down
Adverse effect of the sectional area of distal cannula 10 processed to blood pressure measurement precision.
In addition, in the present embodiment, the center line L1 of extended segment 111 can be formed with the center line L2 of bending section 112
Predetermined angular θ (referring to fig. 4).From the point of view of the sectional area increase for inhibiting distal cannula 10, L1 and L2 are formed by regulation angle
Degree θ is preferably greater than zero less than 90 °.In some instances, L1 and L2 be formed by predetermined angular θ for example can for 20 ° extremely
60°.In addition, from the viewpoint of be easy to connect medical guiding wire 2, it is preferably 30 ° to 50 ° that L1 and L2, which are formed by predetermined angular θ,.
As described above, medical guiding wire 2 can enter from the receiving port 11a of the extended segment of guidewire lumen 11 111, and along
Extended segment 111 relatively moves, and subsequently into bending section 112, finally exports from the guide port 11b of bending section 112.In addition, one
In a little examples, medical guiding wire 2 from the guide port 11b of bending section 112 can also enter guidewire lumen 11 and in guidewire lumen 11
Interior relative movement or opposite sliding, and stretched out from the receiving port 11a of extended segment 111.
In addition, in the present embodiment, medical guiding wire 2 will receive bending section 112 when relatively moving along guidewire lumen 11
Constraint so that the moving direction of medical guiding wire 2 can occur to change accordingly.Thereby, it is possible to inhibit medical guiding wire 2 (specifically
It is introduced into one end of guidewire lumen 11) distal cannula 10 or proximal part 20 are caused to damage.
In addition, in the present embodiment, since medical guiding wire 2 can be from side (the specifically bending section of distal cannula 10
112 guide port 11b) it stretches out or enters, therefore distal cannula 10 can for example be connected in coaxial fashion with proximal part 20
It connects.In such a case, it is possible to effectively inhibit intravascular pressure measurement conduit 1 whole (especially distal cannula 10 and proximal end
The connection place of part 20) the increase of cross-sectional area and can will be measured consequently facilitating measurement conduit 1 moves in the blood vessels
Conduit 1 is sent to narrower blood vessel.
In addition, the present invention is not although including extended segment 111 and bending section 112 described above is guidewire lumen 11
It is limited to this.For example, in some instances, guidewire lumen 11 can be only made of above-mentioned extended segment 111.In this case,
Distal cannula 10 and proximal part 40 such as staggered positions can not also be connected (not shown) in a continuous manner.
In addition, in some instances, distal cannula 10 can be preferably by working as selected from polyimides (PI), polyester or nylon
At least one of constitute.Thereby, it is possible to ensure distal cannula 10 by can adapt to blood vessel when the complicated blood vessel of shape bending
Shape and deformation occurs, thus inhibit measure conduit 1 the damage caused by blood vessel of distal cannula 10.
(proximal part)
In the present embodiment, as depicted in figs. 1 and 2, proximal part 20 (specifically one end of proximal part 20) and remote
End cap pipe 10 couples (connection).In addition, one end of proximal part 20 and the connecting mode of distal cannula 10 are not particularly limited, example
It can such as be coupled by bonding way, can also be coupled by connector such as protection pipe 50 (being described later on).
In addition, in the present embodiment, proximal part 20 can connect with distal cannula 10 in such a way that outer surface is continuous,
It can also for example staggered positions connect in a discontinuous manner.In some instances, proximal part 20 can be with distal cannula 10
There are the parts of overlapping, and in other examples, proximal part 20 can be separated from each other with distal cannula 10 and by protection pipe 50
Connection.
In addition, in the present embodiment, proximal part 20 (the specifically other end of proximal part 20) is along the solution of body
It cuts open structure (such as blood vessel) and extends to and for example connect in vitro with above-mentioned external equipment (not shown).In order to facilitate expression, attached drawing
In do not show that the part of the proximal part 20 connecting with external equipment outside patient body.This segment proximal part 20 is general
The part that can be used as the operation such as doctor (such as position of push and adjustment distal portions 10) blood pressure measurement conduit 1, passes through behaviour
Make the part, can make blood pressure measurement conduit 1 further to blood vessel depths propulsion in patient body or blood vessel from the patient
It exits.
Fig. 5 shows the close of the intravascular pressure measurement conduit involved in the 1st embodiment of the invention with developing ring
The partial sectional schematic view of end part.In Fig. 5, a part of proximal part 20 is illustrated only, especially proximate to distal cannula
10 part.
In the present embodiment, proximal part 20 may include proximal end outer tube 21 and the core that is set to inside proximal end outer tube 21
Axis 22.In addition, in proximal part 20, it can be with filled media or protective glue (not shown) between proximal end outer tube 21 and mandrel 22.
It should be noted that proximal end outer tube 21 and mandrel 22 shown in Fig. 5 are not necessarily to scale description, for example, in some instances, core
The diameter of axis 22 can be greater or lesser.In addition, mandrel 22 can also fill the pipe of proximal end outer tube 21 in other examples
Chamber.
In addition, in the present embodiment, the mandrel 22 of proximal part 20 can be by distal portions 10 and outside in vitro
The connection (not shown) of portion's equipment.In addition, the conducting wire 23 (referring to Fig. 6) being connected with pressure sensor 40 can be set in proximal end
In the mandrel 22 of part 20, conducting wire 23 is allowed to be drawn out to external external equipment along mandrel 22, thus, it is possible to will
The blood pressure signal that pressure sensor 40 is sensed is transmitted to external equipment.In addition, in some instances, conducting wire 23 can also be arranged in
Between mandrel 22 and proximal end outer tube 21, in this case, the blood pressure that conducting wire 23 can will equally be sensed by pressure sensor 40
Signal is transmitted to external equipment.
In addition, in the present embodiment, the constituent material of proximal part 20 is not particularly limited, it is preferable to use hardness is higher
Material.Thus, it is possible to ensure that doctor (and can be set distal cannula 10 by proximal part 20 in interventional procedure
Set developing ring 30 and pressure sensor 40 in distal cannula 10) it is advanced in patient's blood vessel along medical guiding wire 2, Jin Erding
At position to stenotic lesion.
In addition, in the present embodiment, proximal part 20 is usually harder than distal cannula 10 and has more rigidity, so as to
It preferably can move and promote distal cannula 10.In the present embodiment, proximal part 20 can be by medical stainless steel for example
Hypotube is constituted.In addition, in some instances, proximal part 20 can also be by other materials such as Nitinol, nylon, plastics
Deng composition.
In addition, in the present embodiment, the shape of proximal part 20 is not particularly limited, and in some instances, close end
Points 20 can be in extension of shape elongated tubular, it is rectangular tubular that proximal part 20 can also be in extension of shape, ellipse in other examples
It is round tubular etc..In the present embodiment, from easy to process and be conducive to from the viewpoint of moving in the blood vessels, proximal part 20 is excellent
Choosing is in elongated tubular.
In addition, the length of proximal part 20 is not particularly limited, as long as ensuring that the length of proximal part 20 can be from patient
The predetermined position (such as affected area) of (such as vein, artery) extends to monitoring device outside patient body etc. in vivo.Proximal end
The typical length of part 20 is, for example, 60cm to 200cm, the length of certain proximal part 20 can also longer such as 300cm, or
The shorter such as 50cm of person.
(developing ring)
In the present embodiment, developing ring 30 can be set in the front end of distal cannula 10.In addition, in some instances,
Developing ring 30 can be set in the front end of distal cannula 10.But present embodiment is without being limited thereto, for example, developing ring 30 can be with
It is set to any other position of distal cannula 10.
In the present embodiment, developing ring 30 may include the material opaque to X-ray.In this case, by
To when x-ray bombardment, developing ring 30 is capable of forming opaque pattern.By the opaque pattern, doctor etc. can be rapid
Ground finds developing ring 30, and anatomical structure (such as coronal arteries and veins blood vessel of heart) positions accordingly in vivo, plays the work of positioning identifier
With.In the present embodiment, pressure sensor 40 can be set on developing ring 30, it is possible thereby to pass through the mark of developing ring 30
Effect more accurately navigates to the position of pressure sensor 40.
Specifically, just capableing of the position of pressure sensors 40 by the position where developing ring 30.Therefore, exist
Doctor, just being capable of positioning pressure by the position for the developing ring 30 that the technologies such as X-ray irradiation determine when carrying out intervention surgical procedure
The position of sensor 40, thereby, it is possible to the positions of more accurate positioning pressure sensing, improve the measurement of blood pressure measurement conduit 1
Accuracy or precision.
Fig. 6 shows the pressure of the intravascular pressure measurement conduit involved in the 1st embodiment of the invention with developing ring
The structural schematic diagram of force snesor and developing ring.
In the present embodiment, as shown in fig. 6, developing ring 30 can have stage portion 31.As described above, pressure sensor
40 can be specifically set in the stage portion 31 of developing ring 30.Thereby, it is possible to further buffer distal cannula 10 and pressure sensing
Influence between device 40, so as to further increase the measurement accuracy or accuracy of pressure sensor 40.
In addition, in the present embodiment, it is also possible that between the sensing part 41 and developing ring 30 of pressure sensor 40
There are gaps (to be described later on).Thereby, it is possible to avoid the sensing part 41 of pressure sensor 40 and the contact of developing ring 30.?
In this case, even if developing ring 30 is squeezed in the blood vessels or when deformation occurs, also can effectively inhibit to pressure sensing
The adverse effect of the special sensing part 41 of device 40, to further effectively improve the measurement accuracy of pressure sensor 40.
In the present embodiment, the Young's modulus of developing ring 30 can be greater than the Young's modulus of distal cannula 10, that is, aobvious
The rigidity (or hardness) of shadow ring 30 is greater than the rigidity (or hardness) of distal cannula 10.Even if occurring as a result, in distal cannula 10 curved
It is bent or be squeezed it is equal in the case where, developing ring 30 is also less likely to occur deformation, thus effectively inhibition distal cannula 10 occur it is curved
It is bent or when being squeezed to the adverse effect of pressure sensor, thus, it is possible to further increase the measurement accuracy of pressure sensor 1.
In addition, in some instances, developing ring 30 can be made of stainless steel, metal alloy or hard engineering plastic.Its
In, metal alloy can be cochrome, titanium alloy；Hard engineering plastic can be acrylonitrile-butadiene-styrene copolymer
(ABS), polymethyl methacrylate (PMMA), polyethylene terephthalate (PET) or polybutylene terephthalate
Ester (PBT) etc..By using above-mentioned material, it can make developing ring 30 that there is enough flexural strengths, even if thus covering in distal end
When pipe 10 occurs bending and deformation, the stress deformation of developing ring 30 can be also effectively inhibited.
It in addition, the shape of developing ring 30 is not particularly limited, such as can be hollow cylinder shown in present embodiment
Shape.In addition, developing ring 30 or other shapes, such as or the hollow cubic bodily form, hollow irregular shape etc..
In some instances, the size of developing ring 30 can match with the outer diameter of distal cannula 10.In addition, developing ring 30
It can be fixed in distal cannula 10, can also be made of one piece with distal cannula 10 by modes such as welding.
(pressure sensor)
In the present embodiment, as described above, pressure sensor 40 can be set on developing ring 30 (referring to Fig. 6).?
In this case, directly stress variation caused by deformation directly will not be passed when distal cannula 10 moves in the blood vessels
Pressure sensor 40 is passed, inhibits distal cannula 10 to adversely affect to caused by pressure sensor 40, thus, it is possible to improve pressure
The measurement accuracy of sensor 40.
In the present embodiment, as shown in fig. 6, pressure sensor 40 may include sensing part 41 and lead portion 42.
Sensing part 41 can have the sensing area of sensing pressure, can sense or measure the intravascular blood pressure of patient.Pressure sensor
40 by detecting intravascular blood pressure and generating blood pressure signal, which is exported by lead portion 42, and via signal
Access (conducting wire 23) and be sent to for example external processing equipment (not shown).
In the present embodiment, the lead portion 42 of pressure sensor 40 can be fixed on the stage portion 31 of developing ring 30,
And there are gap between sensing part 41 and stage portion 31 (referring to Fig. 6).Thereby, it is possible to avoid the sensing of pressure sensor 40
The contact of part 41 and developing ring 30, in this case, even if developing ring 30 is squeezed in the blood vessels or when deformation occurs,
Also the adverse effect to the special sensing part 41 of pressure sensor 40 can effectively be inhibited.
In addition, in the present embodiment, the conducting wire 23 being connected with pressure sensor 40 can be communicated to outside patient
The Medical Devices such as the equipment in portion such as processor, display, computer, monitor.In some instances, connecting wire 23 can also
To be arranged in 20 inner tube of proximal part, proximal part 20 is made at least partly to coat connecting wire 23, i.e. connecting wire 23 at least
It is partially housed in proximal part 20.Proximal part 20 can play the role of support and protection connecting wire 23 as a result,.Separately
Outside, in some embodiments, connecting wire 23 can also be configured along the outer surface of proximal part 20.
In addition, in the present embodiment, the type of pressure sensor 40 is not particularly limited, such as it can be condenser type pressure
Force snesor, resistive pressure sensor are also possible to MEMS pressure sensor etc..Therefore, according to application scenarios or can make
With desired difference, different configuration and design are carried out, the widespread popularity of its blood pressure measurement conduit 1 is improved.
It in addition, in the present embodiment, the shape of pressure sensor 40 is not particularly limited, such as can be this embodiment party
Cuboid shown in formula.It can also be other shapes, such as or cylindrical, irregular shape etc. certainly.
In addition, in the present embodiment, on the surface of pressure sensor 40, Parylene can be coated with
(Parylene), silica gel, gel at least one of are worked as.In this case, pressure sensor 40 can satisfy intervention operation
Requirement to biocompatibility.
In addition, in some instances, on the outer wall of distal cannula 10, by bonding way such as dispensing by pressure sensing
The lead portion 42 of device 40 is fixed in distal cannula 10.In this case, it can be avoided the push process in measurement conduit 1
Middle lead portion 42 is separated with distal cannula 10, improves the soldering reliability between lead portion 42 and sensing part 41.
(protection pipe)
Fig. 7 shows the intravascular pressure measurement conduit involved in the 1st embodiment of the invention with developing ring and passes through
The schematic perspective view of protection pipe connection distal cannula and proximal part.
In the present embodiment, as shown in fig. 7, distal cannula 10 can couple with proximal part 20 via protection pipe 50,
Protection pipe 50 partially can cover or be completely covered distal cannula 10 and proximal part 20, but present embodiment is without being limited thereto.Example
Such as, distal cannula 10 can also be coupled by welding with proximal part 20, can also be by protection pipe 50 and proximal part 20 1
It is body formed to form coupling structure.
As shown in fig. 7, protection pipe 50 has the opening 51 of 40 measurement position of corresponding pressure sensor and covers with distal end
The corresponding side opening 52 of the guide port 11b of pipe 10.In this case, medical guiding wire 2 can be via the protection of distal cannula 10
The receiving port 11a of pipe is imported and is exported from the guide port 11b of distal cannula 10 and side opening 52.Thereby, it is possible to make blood pressure measurement
Conduit 1 is moved along medical guiding wire 2.
[the 2nd embodiment]
Fig. 8 shows the vertical of the intravascular pressure measurement conduit involved in the 2nd embodiment of the invention with developing ring
Body structural schematic diagram.
As shown in figure 8, present embodiment is with the 1st embodiment the difference lies in that the position of developing ring 30 is arranged close
In end part 20.It just can determine the position of pressure sensor 40 by 30 position of locating development ring as a result,.In such case
Under, doctor is when being operated, the position for the developing ring 30 that can be determined for example, by the methods of X-ray irradiation, to determine
The position of pressure sensor 40, thereby, it is possible to the positions of more accurately positioning pressure sensing, improve intravascular pressure measurement and lead
The accuracy of measurement or precision of pipe, equally can be realized function and effect described in the 1st embodiment.
In the present embodiment, the Young's modulus of developing ring 30 can be greater than the Young's modulus of proximal part 20.This
In the case of, even if proximal part 20 bends or deformation etc., developing ring 30 is also less likely to occur deformation, and thus, it is possible to effectively press down
Proximal part 20 processed improves the measurement accuracy of pressure sensor 40 to the adverse effect of pressure sensor 40.
In addition, in the present embodiment, the conducting wire 23 being connected with pressure sensor 40 can be set in proximal part 20
Mandrel 22 in, allow conducting wire 23 to be drawn out to external external equipment (not shown) along mandrel 22, thus, it is possible to
The blood pressure signal that pressure sensor 40 is sensed is transmitted to external equipment.
In addition, in some instances, conducting wire 23 can also be arranged between mandrel 22 and proximal end outer tube 21, at other
In example, conducting wire 23 be can be set in the outer surface of the proximal end outer tube 21 of proximal part 20.In this case, conducting wire 23 is same
The blood pressure signal sensed by pressure sensor 40 can be transmitted to external equipment.
Although above combine drawings and embodiments the present invention is illustrated, it will be appreciated that on state
It is bright that the invention is not limited in any way.Those skilled in the art are without departing from the true spirit and scope of the present invention
It can according to need and the present invention is deformed and is changed, these deformations and variation are within the scope of the present invention.
Claims (10)
1. a kind of intravascular pressure with developing ring measures conduit, it is characterised in that:
Include:
Distal cannula has the guidewire lumen slideably received within individual medical guiding wire；
Developing ring, is set to the front end of the distal cannula, and the developing ring has stage portion；
Pressure sensor is arranged in the stage portion of the developing ring, for measuring endovascular blood pressure and generating blood
Press signal；And
Proximal part couples with the distal cannula, and including for transmitting the blood from the pressure sensor
It presses the signal path of signal and is used to support the connecting conduit of the signal path and the mobile distal cannula.
2. a kind of intravascular pressure with developing ring measures conduit, it is characterised in that:
Include:
Distal cannula has the guidewire lumen slideably received within individual medical guiding wire；
Proximal part couples with the distal cannula；
Developing ring, is set to the proximal part, and the developing ring has stage portion；And pressure sensor, setting exist
In the stage portion of the developing ring, for measuring endovascular blood pressure and generating blood pressure signal；
Wherein, the proximal part include for transmit the signal path of the blood pressure signal from the pressure sensor,
And it is used to support the connecting conduit of the signal path and the mobile distal cannula.
3. intravascular pressure as claimed in claim 1 or 2 measures conduit, it is characterised in that:
The developing ring includes the material opaque to X-ray.
4. intravascular pressure as claimed in claim 1 or 2 measures conduit, it is characterised in that:
The distal cannula couples with the proximal part via protection pipe.
5. intravascular pressure as claimed in claim 1 or 2 measures conduit, it is characterised in that:
The pressure sensor includes sensing part and lead portion, and the sensing part has the sensing area of sensing pressure, institute
Lead portion is stated to export the blood pressure signal generated by the sensing area.
6. intravascular pressure as claimed in claim 5 measures conduit, it is characterised in that:
There are gaps with the developing ring for the sensing part of the pressure sensor.
7. intravascular pressure as described in claim 1 measures conduit, it is characterised in that:
The Young's modulus of the developing ring is greater than the Young's modulus of the distal cannula.
8. intravascular pressure as claimed in claim 2 measures conduit, it is characterised in that:
The Young's modulus of the developing ring is greater than the Young's modulus of the proximal part.
9. intravascular pressure as claimed in claim 1 or 2 measures conduit, it is characterised in that:
The signal path is at least partially accommodated into the connecting conduit.
10. intravascular pressure as claimed in claim 5 measures conduit, it is characterised in that:
The lead portion of the pressure sensor is fixed on the stage portion, and the sensing part and the stage portion
There are gaps.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201811304678.3A CN109124608A (en) | 2017-10-21 | 2017-10-21 | Intravascular pressure with developing ring measures conduit |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201811304678.3A CN109124608A (en) | 2017-10-21 | 2017-10-21 | Intravascular pressure with developing ring measures conduit |
| CN201710987577.XA CN107569223A (en) | 2017-10-21 | 2017-10-21 | Intravascular pressure measurement conduit with developing ring |
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| CN201710987577.XA Division CN107569223A (en) | 2017-10-21 | 2017-10-21 | Intravascular pressure measurement conduit with developing ring |
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| CN109124608A true CN109124608A (en) | 2019-01-04 |
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| CN201811304678.3A Pending CN109124608A (en) | 2017-10-21 | 2017-10-21 | Intravascular pressure with developing ring measures conduit |
| CN201710987577.XA Pending CN107569223A (en) | 2017-10-21 | 2017-10-21 | Intravascular pressure measurement conduit with developing ring |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN113616176A (en) * | 2019-12-31 | 2021-11-09 | 深圳北芯生命科技股份有限公司 | Intravascular pressure measurement system with retraction device |
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| CN117582192A (en) * | 2019-08-02 | 2024-02-23 | 深圳北芯生命科技股份有限公司 | Pressure measuring catheter |
| CN115568836A (en) * | 2019-08-07 | 2023-01-06 | 深圳北芯生命科技股份有限公司 | Intravascular pressure measurement catheter capable of indicating position of pressure sensor |
| CN112378557B (en) * | 2020-11-12 | 2022-03-18 | 北京航空航天大学 | Interventional instrument front end stress detection method and system based on X-ray image |
| CN114469333B (en) * | 2021-07-05 | 2024-02-20 | 深圳市中科融光医疗科技有限公司 | Ablation catheter, laser ablation system and intravascular laser plaque ablation method |
| CN114681756B (en) * | 2022-03-15 | 2024-04-19 | 深圳市纬思精准科技有限公司 | Conveying conduit |
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| CN107569223A (en) | 2018-01-12 |
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Address after: Area E, 3 / F, building 3, Tingwei Industrial Park, No.6 Liufang Road, Xin'an street, Bao'an District, Shenzhen City, Guangdong Province Applicant after: Shenzhen Beixin Life Technology Co.,Ltd. Address before: Area E, 3 / F, building 3, Tingwei Industrial Park, No.6 Liufang Road, Xin'an street, Bao'an District, Shenzhen City, Guangdong Province Applicant before: INSIGHT LIFETECH Co.,Ltd. (SHENZHEN ) |
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