CN109044406A - Controllable reciprocating ultrasonic scanning capsule endoscope - Google Patents

Controllable reciprocating ultrasonic scanning capsule endoscope Download PDF

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Publication number
CN109044406A
CN109044406A CN201811071270.6A CN201811071270A CN109044406A CN 109044406 A CN109044406 A CN 109044406A CN 201811071270 A CN201811071270 A CN 201811071270A CN 109044406 A CN109044406 A CN 109044406A
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capsule
module
reciprocating
ultrasonic
motor
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CN109044406B (en
Inventor
张睿
郑文帅
解丹
马健喆
潘理虎
张永梅
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Taiyuan University of Science and Technology
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Taiyuan University of Science and Technology
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/12Diagnosis using ultrasonic, sonic or infrasonic waves in body cavities or body tracts, e.g. by using catheters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/44Constructional features of the ultrasonic, sonic or infrasonic diagnostic device
    • A61B8/4444Constructional features of the ultrasonic, sonic or infrasonic diagnostic device related to the probe
    • A61B8/4472Wireless probes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/54Control of the diagnostic device

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medical Informatics (AREA)
  • Surgery (AREA)
  • Pathology (AREA)
  • Radiology & Medical Imaging (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Computer Networks & Wireless Communication (AREA)
  • Ultra Sonic Daignosis Equipment (AREA)
  • Endoscopes (AREA)

Abstract

The invention discloses a kind of controllable reciprocating ultrasonic scanning capsule endoscopes, the present apparatus is while realizing capsule optical scanner, ultrasonic sensor array high-resolution, on a large scale reciprocating scanning imagery are realized using ASIC circuit module and reciprocating scan driver module, and the real-time Transmission of detection data is realized using wireless transport module, the real-time diagnosis for thus allowing for no foreign body sensation formula repeatability in alimentary canal, improves the accuracy rate of diagnosis.Furthermore, the present apparatus combines MEMS micro-processing technology and integrated circuit technique, the diagnosis effect of disease of digestive tract can either be improved, again the medical treatment cost of disease of digestive tract diagnosis, final high-performance, micromation, the low cost manufacturing for realizing ultrasonic capsule can be reduced by reducing the cost of disposable medical machinery.

Description

Controllable reciprocating ultrasonic scanning capsule endoscope
Technical field
The present invention relates to capsule endoscope technical field, specially a kind of controllable reciprocating ultrasonic scanning capsule endoscope.
Background technique
Capsule endoscope technology is the important means of current disease of digestive tract diagnosis, can be noninvasive painless and without complication In the case where complete disease of digestive tract inspection, realize low invasion, Noninvasive diagnosis.Existing oral capsule endoscope in the market In mostly use optical imaging sensor greatly, its working principle is that patient swallows one piece of capsule, after which enters in vivo, It can be moved in alimentary canal with the wriggling of stomach and intestine, while optical image sensor acquires alimentary canal surface layer image and deposited Storage, later, image are sent to external receiving device in a manner of relying on wireless transmission in the form of digital signal, and are working Restore image on standing for diagnosis, after the completion of detection, capsule is excreted with excreta.Whole process will not be to patient's Normal life has an impact, and is more not in discomfort brought by traditional plug-in type endoscope.This capsule endoscope can obtain Clearly alimentary canal surface picture, but be difficult to obtain the Multi-level Organization Structure feature under pipeline parietal layer, thus for some viscous The disease of film lower layer can not be found out, and be such as difficult to differentiate the growth level of tumour in wall, be cannot achieve any level in each layer structure Anomalous variation diagnosis, and then can not judge tumor-infiltrated situation.
Currently, existing ultrasound capsule endoscope has ultrasonic probe transmitting-receiving separation and single plane minute-pressure electricity array element transceiver Two kinds.It is external sensor transmitting that ultrasonic probe, which receives and dispatches isolated capsule endoscope, is received in internal capsule, is accomplished that capsule is fixed Bit function but cannot achieve the imaging of alimentary canal internal ultrasonic;Though and the capsule endoscope of single plane minute-pressure electricity array element transceiver 360 ° of rotary scannings of capsule wall so may be implemented, but single array element planar structure imaging effect is poor, and can not achieve anti-on a large scale Multiple scanning.
Aiming at the problem that existing capsule endoscope can not check submucosa tissue lesion situation, this patent utilizes ultrasonic wave side The advantage of tropism is good, penetration capacity is strong, highly-safe feature and capsule endoscope proposes a kind of MEMS ultrasound capsule endoscope dress It sets, on the basis of existing optics capsule endoscope, is embedded in dynamic scan MEMS ultrasound transceiver array, can both be peeped by interior Mirror observes directly the pathological change form of mucomembranous surface, and can carry out controllable reciprocating ultrasonic scanning, obtains digestive organs tube wall The diagnosis capability of endoscope improves to expand the diagnostic area of capsule endoscope in the tissue signature of each tomography.
Summary of the invention
The object of the present invention is to provide a kind of capsule endoscope devices of controllable reciprocating ultrasonic scanning, it is a kind of novel Medical device can realize the inspection to digestive tract wall undertissue structure, alimentary canal is greatly improved under conditions of noninvasive painless The diagnosis efficiency and accuracy of disease.
The present invention is achieved by the following technical scheme:
Optics front cover is installed in a kind of controllable reciprocating ultrasonic scanning capsule endoscope, including capsule shell, the capsule shell front end, It is located at optics front cover rear in the capsule shell and camera lens is installed, mounted LED lamp around the camera lens, inside the capsule shell Optical image sensor, power module and memory module, wireless transport module are installed, the camera lens exports image information to optics Imaging sensor, the optical image sensor output information to wireless transport module, the wireless transport module are bi-directionally connected Memory module, the power module are powered to LED light, optical image sensor, memory module and wireless transport module.
Reciprocating driving part is installed, the reciprocating driving part includes motor and and motor inside the capsule shell Be relatively fixed support, and the motor is installed in the middle part of capsule shell, and the motor installs driving wheel, institute by motor transmission shaft It states hold-down support and is installed on tail portion in capsule shell, pass through fixing axle installation driven wheel, the driving wheel on the hold-down support It is tensioned and is connected by transmission belt between driven wheel;It is visited on the conveyer belt by sensor connecting rod mounting circular ring shape ultrasound Head, i.e. transmission belt are located in circular ring shape ultrasonic probe, and drive circular ring shape ultrasonic probe to realize and move back and forth;The circular ring shape is super Sonic probe output information is to ASIC circuit module, the ASIC circuit module output information to wireless transport module.
The present apparatus is real using ASIC circuit module and reciprocating scan driver module while realizing capsule optical scanner Existing ultrasonic sensor array high-resolution, on a large scale reciprocating scanning imagery, and detection data is realized using wireless transport module Real-time Transmission, thus allow for the real-time diagnosis of no foreign body sensation formula repeatability in alimentary canal, improve the accuracy rate of diagnosis.This Outside, the present apparatus combines MEMS micro-processing technology and integrated circuit technique, can either improve the diagnosis effect of disease of digestive tract, The medical treatment cost of disease of digestive tract diagnosis can be reduced by reducing the cost of disposable medical machinery again, it is final to realize ultrasonic glue High-performance, micromation, the low cost manufacturing of capsule.
With existing Technical comparing, advantages of the present invention is as follows:
1, cMUT circular array ultrasonic probe is realized using MEMS micro-processing technology.The scanning of cMUT circular array ultrasonic probe Range is big, scanning resolution with higher, can be with 360 ° inside the realization alimentary canal of low-power consumption ultrasonic depth diagnosis.
2, signal processing special circuit can be realized the micromation and low cost system of ultrasonic capsule using integrated circuit technique It makes.
3, circular ring shape ultrasonic probe is fixed on reciprocating driving part the at the uniform velocity fortune that forward and reverse is carried out with transmission belt Multiple scanning and diagnosis, it can be achieved that alimentary canal inner wall are moved, to more accurately be analyzed.
4, reciprocating driving part not only can control stroke range, but can use motor drive driving wheel and driven wheel into The reciprocating of transmission belt at the uniform velocity is realized in the rotation of row forward and reverse, so that probe be driven to be moved accordingly.This device It is simple and easy, the accuracy rate of scanning can be improved in the case where low cost low-power consumption.
The present invention has rational design, the specific application of market well and promotional value.
Detailed description of the invention
Fig. 1 shows this ultrasound capsule endoscope image-forming detecting system the general frames.
Fig. 2 indicates the schematic illustration of this ultrasound capsule endoscope device.
Fig. 3 indicates the structural schematic diagram of this ultrasound capsule endoscope device.
Fig. 4 a indicates the reciprocating driver main view in this ultrasound capsule.
Fig. 4 b indicates the reciprocating driver side view in this ultrasound capsule.
Fig. 4 c indicates the reciprocating driver shaft side figure in this ultrasound capsule.
Fig. 4 d indicates the circular ring shape ultrasonic probe schematic diagram in this ultrasound capsule.
Fig. 5 indicates external storage modular structure block diagram of the present invention.
Fig. 6 indicates image reconstruction of the present invention and human-computer interaction structural block diagram.
In figure, 1- optics front cover, 2-LED lamp, 3- camera lens, 4- power module, 5- optical image sensor, 6- storage mould Block, 7- wireless transmission, 8-ASIC circuit module, the reciprocating driving part of 9-, 10- circular ring shape ultrasonic probe, 11- capsule shell; 91- motor, 92- driving wheel, 93- motor transmission shaft, 94- transmission belt, 95- fixing axle, 96- driven wheel, 97- hold-down support, 98- Sensor connecting rod.
Specific embodiment
Specific embodiments of the present invention are described in detail with reference to the accompanying drawing.
As shown in Figure 1, the detection system of the ultrasonic capsule endoscope with reciprocating scanning function comprising controllable reciprocating Ultrasonic scanning capsule endoscope, external storage and image reconstruction man-machine interactive system three parts.Specifically, controllable reciprocating super Sound scans capsule endoscope and carries out optical imagery and ultrasonic imaging, by the image of formation by wireless transmission, is transferred to external deposit It stores up in module, leads to USB transmission later to computer, carry out graphics process and reconstruction, realize human-computer interaction.The process of ultrasonic imaging In, the acoustic impedance that its intensity is organized while sound wave is propagated in organ-tissue is modulated, later receives echo-signal Exactly the tissue acoustic characteristic carried in sound wave is demodulated to come.Echo-signal is relied on wireless transmission by system in digital form Mode is transferred in vitro, is saved on external storage device, using computation calculation processing, shows organ walls tomography tissue Gray level image.
As shown in Fig. 2, being equipped with ultrasonic optical imagery module in controllable reciprocating ultrasonic capsule endoscope, circular ring shape ultrasound is visited Head, ASIC circuit module, reciprocating drive module, wireless transport module, power module, memory module, capsule shell Encapsulation Moulds Block.Capsule shell package module is packaged each module in ultrasonic capsule;Optical imagery module to alimentary canal wall surface into Row detection;Circular ring shape ultrasonic probe and ASIC circuit module realize the transceiving integrated of ultrasound;Reciprocating drive module drives circle Ring-shaped ultrasonic probe carries out shuttle movement in capsule, realizes that the repetition to digestive tract wall undertissue structure detects;Nothing The result that line transmission module will test is stored to external;The wireless receiving circuit of external external storage section carries out detection data It receives, will test data storage under the action of control unit into storage unit, and man-machine to image reconstruction by USB transmission Interactive system;Image reconstruction man-machine interactive system reads the detection data that external storage part transmits with USB interface, and right Data are handled to realize image reconstruction and display.
As shown in figure 3, the above-mentioned ultrasonic capsule endoscope device with reciprocating scanning function includes capsule shell 11, glue Lateral one end of capsule shell 11 is equipped with optics front cover 1, in capsule shell 11 other end lateral from optics front cover 1 to capsule according to It is secondary to be packaged with LED light 2, camera lens 3, power supply 4, optical image sensor 5, memory module 6, wireless transport module 7, ASIC circuit mould Block 8, reciprocating driving part 9, circular ring shape ultrasonic probe 10.Specific connection relationship is, before optics is installed in 11 front end of capsule shell Lid 1 is located at 1 rear of optics front cover in capsule shell 11 and installs camera lens 3,3 surrounding mounted LED lamp 2 of camera lens, inside capsule shell 11 Optical image sensor 5, power module 4 and memory module 6, wireless transport module 7 are installed, camera lens 3 exports image information to light Imaging sensor 5 is learned, 5 output information of optical image sensor to wireless transport module 7, wireless transport module 7, which is bi-directionally connected, to be deposited Module 6 is stored up, power module 4 is powered to LED light 2, optical image sensor 5, memory module 6 and wireless transport module 7;Outside capsule Reciprocating driving part 9 is installed, reciprocating driving part 9 includes motor 91 and is relatively fixed support with motor 91 inside shell 11 97, motor 91 is installed on 11 middle part of capsule shell or tail portion, and motor 91 installs driving wheel 92 by motor transmission shaft 93, fixed Support 97 is installed on tail portion or middle part in capsule shell 11, passes through the installation driven wheel 96 of fixing axle 95, master on hold-down support 97 Pass through the tensioning connection of transmission belt 94 between driving wheel 92 and driven wheel 96;Pass through 98 mounting circular ring of sensor connecting rod on transmission belt 94 Shape ultrasonic probe 10, i.e. transmission belt 94 are located in circular ring shape ultrasonic probe 10, and circular ring shape ultrasonic probe 10 is driven to realize back and forth Movement;10 output information of circular ring shape ultrasonic probe is to ASIC circuit module 8, and 8 output information of ASIC circuit module is to wireless Transmission module 7.Wherein, capsule shell 11 is used to for internal various devices being isolated with outside, keeps away the pollution of face vivo environment And capsule electric leakage causes harm to the human body and forms complete ellipsoid convenient for oral;The optics front cover 1 of capsule one end is used for Light transmission;The close position of optics front cover 1 is arranged in camera lens 3, for external image to be imaged;LED light 2 on camera lens 3 is used It is illuminated around to capsule endoscope, so that imaging is relatively sharp;Power supply 4 is used to provide needed for work for ultrasonic capsule endoscope The energy wanted;Optical image sensor 5 is used to receive the imaging of camera lens 3 and generates picture signal;Memory module 6 is for keeping in glue Intracapsular detection data;Detection data in capsule for being transmitted to external radio receiver, ASCI electricity by wireless transmission 7 Road module 8 uses high level of integrated system technology, by transmit circuit, receives circuit, Power Management Unit, control unit and storage list Member is constituted, for realizing the power supply of the transmitting of ultrasonic pulse, the processing of echo-signal, ultrasonic probe and circuit chip, system control And data buffer storage;As shown in figures 4a-4d, motor 91 and hold-down support 97 are fixed on the suitable position in capsule, by transmission belt 94 It is tensioned and meets the requirement of its stroke range, control circuit realizes the forward and reverse movement of transmission belt by control motor 91, from And circular ring shape ultrasonic probe 10 is driven to carry out reciprocating;Circular ring shape ultrasonic probe 10 is made of a kind of high frequency cMUT array, For realizing the transmitting and reception of ultrasonic wave, be fixedly connected on transmission belt 94 by sensor connecting rod 98 and in capsule Wall keeps suitable distance, and with the rotation of the forward and reverse of motor, circular ring shape ultrasonic probe 10 follows transmission belt 94 in glue It is intracapsular to be moved.
As shown in figure 5, above-mentioned external storage includes that wireless receiving, data buffer storage, storage unit, USB transmission and control are single First five parts.Wherein, control unit controls remaining four part;Wireless receiving is for receiving the testing number that ultrasonic capsule transmits According to being transferred to computer by USB interface after data buffer storage and storage unit are stored later.
As shown in fig. 6, above-mentioned image reconstruction man-machine interactive system have passed through USB transmission, data processing, image reconstruction, people Machine interacts this four steps.The data that USB transmission receives the data computer in external storage section are transferred to computer In disk, reach the reconstruction of image by carrying out data processing to detection data later, to realize human-computer interaction.
Key problem in technology point of the invention is:
1, for ultrasonic capsule endoscope using cMUT circular array as ultrasonic probe, ultrasonic signal for transmitting and receiving can be with Expand investigative range, it can be with 360 ° inside the realization alimentary canal of low-power consumption ultrasonic depth diagnosis;
2, cMUT circular array ultrasonic probe is fixed on the belt, it is controlled by driving wheel, driven wheel and integrated circuit Motor makes ultrasonic probe carry out reciprocating uniform motion with transmission belt, realizes that a certain position is repeated as many times the function of diagnosis of scans Energy.
3, by connecting rod that probe is fixed on the belt, drive probe carries out reciprocal under the action of motor positive and inverse Formula scanning.
4, the module of image procossing is placed in the man-machine interactive system outside capsule, for ultrasound detection data and Optical detection data carry out real-time inspection process.
It should be pointed out that for the those skilled in the art of the art, without departing from the principle of the present invention, Several improvement and application can also be made, these are improved and application is also considered as protection scope of the present invention.

Claims (3)

1. a kind of controllable reciprocating ultrasonic scanning capsule endoscope, including capsule shell (11), capsule shell (11) the front end peace It fills optics front cover (1), optics front cover (1) rear installation camera lens (3), camera lens (3) week is located in the capsule shell (11) It encloses mounted LED lamp (2), installation optical image sensor (5), power module (4) and storage mould inside the capsule shell (11) Block (6), wireless transport module (7), the camera lens (3) export image information to optical image sensor (5), the optical imagery Sensor (5) output information to wireless transport module (7), the wireless transport module (7) is bi-directionally connected memory module (6), institute Power module (4) is stated to power to LED light (2), optical image sensor (5), memory module (6) and wireless transport module (7);
It is characterized by: installing reciprocating driving part (9), the reciprocating driving part inside the capsule shell (11) (9) include motor (91) and be relatively fixed support (97) with motor (91), the motor (91) is installed on capsule shell (11) Middle part, the motor (91) are installed on capsule by motor transmission shaft (93) installation driving wheel (92), the hold-down support (97) Shell (11) interior tail portion passes through fixing axle (95) installation driven wheel (96), the driving wheel (92) on the hold-down support (97) Pass through transmission belt (94) tensioning connection between driven wheel (96);Pacified on the transmission belt (94) by sensor connecting rod (98) It fills circular ring shape ultrasonic probe (10), i.e., transmission belt (94) is located in circular ring shape ultrasonic probe (10), and circular ring shape ultrasound is driven to visit Head (10), which is realized, to be moved back and forth;For circular ring shape ultrasonic probe (10) output information to ASIC circuit module (8), the ASIC is electric Module (8) output information in road is to wireless transport module (7).
2. controllable reciprocating ultrasonic scanning capsule endoscope according to claim 1, it is characterised in that: the ASCI circuit mould Block (8) is made of transmit circuit, reception circuit, Power Management Unit, control unit and storage unit.
3. controllable reciprocating ultrasonic scanning capsule endoscope according to claim 1, it is characterised in that: further include external storage Part, the external storage section include wireless receiving, data buffer storage, storage unit, USB transmission and control unit.
CN201811071270.6A 2018-09-14 2018-09-14 Ultrasonic capsule endoscope detection system with reciprocating scanning function Active CN109044406B (en)

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