CN109035215A - The analysis method of plaque load in a kind of bifurcated lesions - Google Patents
The analysis method of plaque load in a kind of bifurcated lesions Download PDFInfo
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- CN109035215A CN109035215A CN201810732504.0A CN201810732504A CN109035215A CN 109035215 A CN109035215 A CN 109035215A CN 201810732504 A CN201810732504 A CN 201810732504A CN 109035215 A CN109035215 A CN 109035215A
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- plaque load
- branch vessel
- analysis method
- coordinate system
- patch
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- G—PHYSICS
- G06—COMPUTING; CALCULATING OR COUNTING
- G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
- G06T7/00—Image analysis
- G06T7/0002—Inspection of images, e.g. flaw detection
- G06T7/0012—Biomedical image inspection
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- G—PHYSICS
- G06—COMPUTING; CALCULATING OR COUNTING
- G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
- G06T7/00—Image analysis
- G06T7/60—Analysis of geometric attributes
- G06T7/62—Analysis of geometric attributes of area, perimeter, diameter or volume
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- G—PHYSICS
- G06—COMPUTING; CALCULATING OR COUNTING
- G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
- G06T7/00—Image analysis
- G06T7/60—Analysis of geometric attributes
- G06T7/66—Analysis of geometric attributes of image moments or centre of gravity
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- G—PHYSICS
- G06—COMPUTING; CALCULATING OR COUNTING
- G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
- G06T2207/00—Indexing scheme for image analysis or image enhancement
- G06T2207/10—Image acquisition modality
- G06T2207/10132—Ultrasound image
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- G—PHYSICS
- G06—COMPUTING; CALCULATING OR COUNTING
- G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
- G06T2207/00—Indexing scheme for image analysis or image enhancement
- G06T2207/30—Subject of image; Context of image processing
- G06T2207/30004—Biomedical image processing
- G06T2207/30101—Blood vessel; Artery; Vein; Vascular
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- Radiology & Medical Imaging (AREA)
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Abstract
The present invention provides a kind of analysis method of plaque load in bifurcated lesions, comprising: is based on IVUS image, patch is carried out region division, calculates plaque load in each region.The analysis method of plaque load in bifurcated lesions provided by the invention, different from the general blood vessel using where patch of existing comparison as reference, calculate entire plaque load, but orthogonal coordinate system is established according to the relative position of main branch vessel and branch vessel, plaque load region division has been subjected to, pass through this subregional quantitative analysis method, the incidence relation between different patch load and the treatment method bring prognosis of bifurcated lesions is found for doctor, optimal treatment means are found with assessment, there is important application prospect in terms of clinical research.
Description
Technical field
The present invention relates to a kind of analysis sides of plaque load in Medical Image Processing analysis field more particularly to bifurcated lesions
Method.
Background technique
Currently, cardiovascular and cerebrovascular disease gradually becomes an important factor for endangering people's life and health.Coronary artery is athero- hard
Changing lesion is the Etiological for causing myocardial infarction and cerebral infarction, and wherein bifurcation coronary artery refers to the main branch of coronary artery, branch
The lesion of position separately or concurrently existing Serious Stenosis, accounts for the 15%-20% of all percutaneous coronary intervention, is coronal
The difficult point of arterial Interventional Therapy.Mainly according to lesion in the anatomic distribution of bifurcation, more common has the parting of bifurcated lesions
Duke parting, Lefevre parting and Medina parting etc..But these partings there are bifurcation angle status unknown, branch's blood
The problems such as pipe diameter meaning is unclear, it is not in place for the surgical guidance for being implanted into bracket.
Then, the Interventional that intravascular ultrasound (intravenous ultrasound, IVUS) is employed for coronary heart disease is controlled
It treats.The tube wall form and stenosis that blood vessel can be accurately grasped with this method, have very in the Interventional diagnosis and treatment of coronary heart disease
High guiding value establishes suitable therapeutic scheme, the correct size for selecting utensil, the end for determining interventional therapy including guidance
Point and the position and the expansion effect that determine network etc..
But in the prior art research Patch distribution mainly with the blood vessel where patch be referring to (such as
CN103886599A), the factor of consideration is not comprehensive enough, may not be optimal as the treatment method referring to assessment.
Summary of the invention
In view of the deficiencies of the prior art, the present invention provides a kind of analysis method of plaque load in bifurcated lesions, by patch
Load carries out finer region division, is more advantageous to assessment therapeutic scheme.
The present invention provides a kind of analysis method of plaque load in bifurcated lesions, comprising: be based on IVUS image, by patch into
Row region division calculates plaque load in each region.
Preferably, described that patch is subjected to region division specifically: to establish coordinate system, the origin of the coordinate system is main branch
The geometric center of blood vessel.
Preferably, described to establish coordinate system, so that branch vessel is distributed in interior same quadrant or branch vessel and coordinate system
An axis it is tangent.
Preferably, the X-axis of the coordinate system and straight line are at 45 °, and the straight line passes through the geometric center of main branch vessel and divides
The geometric center of branch vessel.
Preferably, the analysis method the following steps are included:
Using the geometric center of main branch vessel as origin, with the straight line is at 45 ° establishes X-axis, Y-axis is in 90 ° with X-axis, builds
Vertical orthogonal coordinate system；
Calculate the plaque load in all quadrants；
The main branch vessel area in plaque area/quadrant in plaque load=quadrant in a certain quadrant.
The analysis method of plaque load in bifurcated lesions provided by the invention, it is general with patch different from existing comparison
The blood vessel at place is reference, calculates entire plaque load, but is established according to the relative position of main branch vessel and branch vessel
Plaque load has been carried out region division by orthogonal coordinate system, by this subregional quantitative analysis method, is found not for doctor
With the incidence relation between plaque load and the treatment method bring prognosis of bifurcated lesions, optimal treatment hand is found with assessment
Section, there is important application prospect in terms of clinical research.
Detailed description of the invention
In order to more clearly explain the embodiment of the invention or the technical proposal in the existing technology, to embodiment or will show below
There is attached drawing needed in technical description to be briefly described, it should be apparent that, the accompanying drawings in the following description is the present invention
Some embodiments for those of ordinary skill in the art without creative efforts, can also basis
These attached drawings obtain other attached drawings.
Fig. 1 is initial IVUS image；
Fig. 2 is the result for determining main branch vessel geometric center；
Fig. 3 is the result for determining branch vessel geometric center；
Fig. 4 is the orthogonal coordinate system established；
Fig. 5 is that postrotational orthogonal coordinate system and quadrant are distributed；
Fig. 6 is plaque load situation in all quadrants.
Specific embodiment
In order to make the object, technical scheme and advantages of the embodiment of the invention clearer, below in conjunction with the embodiment of the present invention
In attached drawing, technical scheme in the embodiment of the invention is clearly and completely described, it is clear that described embodiment is
A part of the embodiment of the present invention, instead of all the embodiments.Based on the embodiments of the present invention, those of ordinary skill in the art
Every other embodiment obtained without creative efforts, shall fall within the protection scope of the present invention.
Embodiment 1
The present embodiment provides a kind of analysis methods of plaque load in bifurcated lesions, comprising the following steps:
Step 1, by ivus image importing computer (as shown in Figure 1), the geometric center of main branch vessel is determined；
Middle film layer along main branch vessel does the first closed curve, calculates and draws the first closed curve inclusion region
Geometric center point 1 (as shown in Figure 2)；
Step 2, the geometric center of branch vessel is determined；
Middle film layer along branch vessel does the second closed curve, calculates and draws the second closed curve inclusion region
Geometric center point 2 (as shown in Figure 3)；
Step 3, geometric center point 1 and geometric center point 2 are connected；
Step 4, orthogonal coordinate system is established；
It is origin with geometric center point 1, using the line of geometric center point 1 and geometric center point 2 as X-axis, wherein close to several
The side of what central point 2 is that X-axis is positive, centered on the origin, rotates 90 ° of the X-axis counterclockwise and obtains Y-axis, to build
Vertical orthogonal coordinate system (as shown in Figure 4)；
Step 5, the orthogonal coordinate system is rotated；
By the orthogonal coordinate system centered on the origin, 45 ° are rotated clockwise；
Step 6, quadrant division is carried out to postrotational orthogonal coordinate system；
Using with the maximum quadrant of branch vessel overlapping area as first quartile, counterclockwise successively determine the second quadrant,
Third quadrant and fourth quadrant (as shown in Figure 5)；
Step 7, the plaque load in all quadrants is calculated；
Third closed curve is done along the lumen of main branch vessel, between first closed curve and the third closed curve
The region surrounded is patch (as shown in Figure 6), calculates the area and plaque load of the patch, and calculate separately in all quadrants
Plaque load,
Wherein, plaque area=main branch vessel area-Lumen Area=the first closed curve inclusion region area-
The area of the third closed curve inclusion region；
Plaque load (Plaque burden)=plaque area/main branch vessel area；
The main branch vessel area in plaque area/first quartile in plaque load=first quartile in first quartile；
And so on, respectively obtain the plaque load in the second quadrant, third quadrant and fourth quadrant.
The above method establishes orthogonal coordinate system according to the relative position of main branch vessel and branch vessel, by plaque load into
Gone region division, by this subregional quantitative analysis method, doctor can count discovery different zones plaque load with point
Pitch lesion treatment method bring prognosis between incidence relation, for follow-up visit bifurcated lesions patient when foundation is provided,
Optimal treatment means are found with assessment.
Finally, it should be noted that the above embodiments are merely illustrative of the technical solutions of the present invention, rather than its limitations；Although
Present invention has been described in detail with reference to the aforementioned embodiments, those skilled in the art should understand that: it still may be used
To modify the technical solutions described in the foregoing embodiments or equivalent replacement of some of the technical features；
And these are modified or replaceed, technical solution of various embodiments of the present invention that it does not separate the essence of the corresponding technical solution spirit and
Range.
Claims (5)
1. the analysis method of plaque load in a kind of bifurcated lesions characterized by comprising be based on IVUS image, by patch into
Row region division calculates plaque load in each region.
2. analysis method according to claim 1, which is characterized in that described that patch is carried out region division specifically: to build
Vertical coordinate system, the origin of the coordinate system is the geometric center of main branch vessel.
3. analysis method according to claim 2, which is characterized in that it is described to establish coordinate system, so that branch vessel is distributed
In same quadrant or an axis of branch vessel and coordinate system is tangent.
4. analysis method according to claim 2, which is characterized in that the X-axis of the coordinate system and straight line are at 45 °, described
The geometric center of geometric center and branch vessel of the straight line Jing Guo main branch vessel.
5. analysis method according to claim 4, which comprises the following steps:
Using the geometric center of main branch vessel as origin, with the straight line is at 45 ° establishes X-axis, Y-axis is in 90 ° with X-axis, establishes just
Hand over coordinate system；
Calculate the plaque load in all quadrants；
The main branch vessel area in plaque area/quadrant in plaque load=quadrant in a certain quadrant.
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| CN201810395369 | 2018-04-27 | ||
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| CN109035215A true CN109035215A (en) | 2018-12-18 |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110246136A (en) * | 2019-05-29 | 2019-09-17 | 山东大学 | A kind of intravascular ultrasound parameter extracting method and system based on hybrid algorithm |
| CN110522449A (en) * | 2019-10-29 | 2019-12-03 | 南京景三医疗科技有限公司 | A kind of patch classifying method, device, electronic equipment and readable storage medium storing program for executing |
| US11436731B2 (en) | 2019-08-05 | 2022-09-06 | Lightlab Imaging, Inc. | Longitudinal display of coronary artery calcium burden |
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| CN105518684A (en) * | 2013-08-27 | 2016-04-20 | 哈特弗罗公司 | Systems and methods for predicting location, onset, and/or change of coronary lesions |
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Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110246136A (en) * | 2019-05-29 | 2019-09-17 | 山东大学 | A kind of intravascular ultrasound parameter extracting method and system based on hybrid algorithm |
| CN110246136B (en) * | 2019-05-29 | 2021-07-02 | 山东大学 | Intravascular ultrasound parameter extraction method and system based on hybrid algorithm |
| US11436731B2 (en) | 2019-08-05 | 2022-09-06 | Lightlab Imaging, Inc. | Longitudinal display of coronary artery calcium burden |
| CN110522449A (en) * | 2019-10-29 | 2019-12-03 | 南京景三医疗科技有限公司 | A kind of patch classifying method, device, electronic equipment and readable storage medium storing program for executing |
| CN110522449B (en) * | 2019-10-29 | 2020-04-17 | 南京景三医疗科技有限公司 | Plaque parting method and device, electronic equipment and readable storage medium |
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