CN108882883A - Parasympathetic autonomic nerves system is measured to while sympathetic autonomic nerves system to independent activities, related and analysis method and system - Google Patents
Parasympathetic autonomic nerves system is measured to while sympathetic autonomic nerves system to independent activities, related and analysis method and system Download PDFInfo
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/40—Detecting, measuring or recording for evaluating the nervous system
- A61B5/4029—Detecting, measuring or recording for evaluating the nervous system for evaluating the peripheral nervous systems
- A61B5/4035—Evaluating the autonomic nervous system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
- A61B5/0205—Simultaneously evaluating both cardiovascular conditions and different types of body conditions, e.g. heart and respiratory condition
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/08—Detecting, measuring or recording devices for evaluating the respiratory organs
- A61B5/0816—Measuring devices for examining respiratory frequency
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
- A61B5/316—Modalities, i.e. specific diagnostic methods
- A61B5/318—Heart-related electrical modalities, e.g. electrocardiography [ECG]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/72—Signal processing specially adapted for physiological signals or for diagnostic purposes
- A61B5/7235—Details of waveform analysis
- A61B5/7253—Details of waveform analysis characterised by using transforms
- A61B5/7257—Details of waveform analysis characterised by using transforms using Fourier transforms
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Abstract
For measuring, related and analysis parasympathetic and while sympathetic autonomic nerves system and the system or method of independent activities, including first sensor and second sensor, wherein first sensor is used to acquire the first independent measured levels of the physiological activity of subject, and second sensor is used to acquire the second independent measured levels of the physiological activity of subject.In addition, the system includes computer, the first independent measured levels of physiological activity and the second independent measured levels of physiological activity are received.Furthermore, the system further includes computer, the computer is programmed to the acquisition time of related first independent measured levels and the second independent measured levels, the numerical value of stomodaeal nervous system activity is compared with the movable numerical value of parasympathetic to determine equilibrium,transient measured value, and equilibrium,transient measured value is compared with the balancing side magnitude of subject.
Description
Technical field
The present embodiment is usually directed to the parasympathetic and stomodaeal nervous system for collectively forming autonomic nerves system
While measured to independent measured levels, it is related and analysis method.
Background technique
Autonomic nerves system is responsible for the control of almost each physiology course in vivo.In general, autonomic nerves system is considered point
At two parts, including stomodaeal nervous system and parasympathetic.The two systems would generally generate stimulation opposite
It influences or reacts, although this is not universal phenomenon.
Stomodaeal nervous system makes body be able to carry out physiological reaction under stressful situation.Stomodaeal nervous system is commonly known as
" fight or flight " system, heart rate and/or blood pressure can be increased and slow down digestion etc..Pair is usually compared in the reaction of stomodaeal nervous system
Stomodaeal nervous system is slow, needs three to five times or more heartbeats.
Parasympathetic enables body self―sustaining.Parasympathetic is commonly known as " rest and digestion "
System can reduce heart rate, blood pressure and/or accelerate digestion.The reaction of parasympathetic is usually faster than stomodaeal nervous system,
One is needed to arrive heartbeat twice.
The coordinate operation of stomodaeal nervous system and parasympathetic shows that a people is being physiologically healthy.This
Outside, a large amount of letters that can be provided about individual physiological state are provided stomodaeal nervous system and parasympathetic function
Breath.
However, to may cause autonomic nerves system unbalance for disease, life style, heredity or environmental condition, lead to sympathetic mind
Leading position excessively frequently or is not enough continually in through system and parasympathetic.
The functional imbalance of autonomic nerves system can damage the function of many organs.Due to vaguely being influenced independently using some
The drug of nervous system, such as beta-blocker, Vel-Tyr-Pro-Trp-Thr-Gln-Arg-Phe, sleep aids, antidepressants, may cause sympathetic nerve
System and parasympathetic are significantly affected, cause further or lasting unbalance.
In addition, simultaneously using a variety of drugs for influencing the various functions of autonomic nerves system, so that：If without it is specific,
Independent but parasympathetic nerve and sympathetic nerve function measured value simultaneously, then being difficult to to overall autonomic nerves system function
The assessment and any certain drug of energy individually influence to measure.
Due to " background " property of stomodaeal nervous system and parasympathetic function, when there is no be not both suitable for
One clinical populations is not generally specific under the hypothesis or approximate situation of single patient yet, is often difficult to determine activity.This
Outside, it is difficult to two systems respectively while carries out precise measurement.
In general, the activity of two systems is all measured as overall autonomic function, and the activity of individual system is based on vacation
If estimating with approximate.However this method is defective, because basic assumption is that two systems normally play a role
And coordinate between proper, or both that (for example, due to disease, the activity level of a system is obvious there are consistent relationship
Higher than another system), no matter environment or clinical consider.In addition, estimated value is based on rule and " rule of thumb ", may go out
Now serious inaccuracy.
Since the function of autonomic nerves system is most important to the long-term health of individual, and many diseases and drug only shadow
A branch of autonomic nerves system is rung, therefore is highly desirable to stomodaeal nervous system and parasympathetic the two systems
Carry out measurement accurate, independent, simultaneously.
Furthermore, it is necessary to measure simultaneously in a precise manner and analyze stomodaeal nervous system and parasympathetic, with true
The function of fixed entire autonomic nerves system is good for provide the instantaneous picture of personal health and to analyze long-term physiology
Health situation.
Detailed description of the invention
Detailed description may be better understood in conjunction with the following drawings：
Fig. 1 is the implementation example figure for measuring the system of Autonomic nervous system activity.
Fig. 2 is the embodiment flow chart for measuring the method for subject's Autonomic nervous system activity.
Fig. 3 is the spectrum waveform example of ECG signal.
Fig. 4 is the spectrum waveform example of ECG signal.
The present embodiment is described in detail using the following drawings.
Specific embodiment
Before this method and system is explained further, it should be appreciated that disclosed method and system is not limited to specific reality
Apply example；On the contrary, disclosed system can be practiced or carried out in many ways.
Specific structure and function details disclosed herein are not necessarily to be construed as limiting, and as just the basis of claim
And for instructing those of ordinary skill in the art to use representative basis of the invention in various ways.Although can be with reference to side
Method or system, but it is understood that the system is for realizing this method, and description here both is suitable for.
The present invention relates to the parasympathetic (PNS) and sympathetic nerve for collectively forming autonomic nerves system (ANS)
It is measured while system (SNS) to independent measured levels, related and analysis method.Measurement can carry out simultaneously or later into
Row is related to provide PNS and SNS movable snapshot at the time of given.
It may include embodiment shown in FIG. 1 for measuring and assessing the movable system of subject ANS.As shown, being
System 10 includes the subject 12 being monitored when executing specific activities.As follows explains in detail, monitored by sensor by
Examination person 12, and these sensors are connected to the computer that can be shifted between multiple subjects 12.In addition, when there are multiple
When subject 12 (that is, the second subject, third subject etc.), more computers can be connected to and these subject's phases
Even more multiple groups sensor come to these subjects carry out and meanwhile monitor.The activity may include the activity of opposite sitting, at this
In the case of kind, system 10, which can be paid close attention to, to be acquired and compares first group of physiological measure.Equally, system 10 can relatively nervous or
Subject 12 is monitored in dynamic situation, can emphasize other physiological measures in this case.The survey collected from subject
Magnitude and/or signal may pass to analysis and the centralization of storing data calculates facility 14 (for example, " cloud ").Centralization calculates
Facility 14 can assess the signal from multiple subjects 12 to monitor the movable variation of ANS of each subject 12.Centralization meter
Calculate facility 14 any change can be notified to subject 12 and/or can be sent to management entity 16 alarm or aggregated data (that is,
Feedback), what be see below explains in detail.
The wearing of subject 12 may include the ANS monitoring system 18 of sensor 20 and computer 22.Sensor 20 can wrap
Electrocardiography transducer 24 is included, which temporarily sticks to the body of subject 12, to connect during specified activities
Continued access is got into the frame of mind for work electrograph (EKG) signal.In another embodiment (not shown), these identical electrocardiography transducers can also be from
Such as impedance plethysmography circuit captures respiratory activity.Sensor 20 can also include for track cardiomotility and the rhythm and pace of moving things its
His sensor 20.ANS monitor system 18 may include respiration transducer, for substitute EKG or heart tracking transducer 24 or with
It is existed simultaneously.For example, sensor 20 may include chest strap sensor 26 or breathing mask 28 to monitor the breathing of subject 12
Mode.Sensor 20 can also include additional sensor 30, for track it is relevant to subject 12 or its ambient enviroment other
Information.For example, additional sensor 30 may include global positioning signal (GPS) tracker, barometric pressure sensor, temperature sensing
Device (it can detecte or can not detect the temperature of subject 12), accelerometer, perspire or sweat detector, heart output pass
Sensor, by shooting blood pressure sensor, blood glucose sensor, pulse blood oxygen instrument (SpO2) sensor, pulse wave velocity sensor or other
Sensor.In addition, computer 22 may include the memory 32 for storing the instruction and data provided by sensor 20, it is used for
The processor 34 (that is, non-transitory data storage media) executed instruction and the network for being communicated with other computer equipments
Equipment 36.The network equipment 36 (such as receiver, transmitter, transceiver etc.) may include wireless telecom equipment, allow to
Subject 12 is monitored in various activities.
For example, subject 12 can be the ling-distance truck driver for being engaged in opposite sedentary activity for a long time.In such item
Under part, subject 12 can be using the form while wearable sensors 20 of underwear, other sensors 30 and computer 22.It passes
Sensor 20 and 30 sends a signal to computer 22, by computer 22 carry out signal storage, analysis and processing with determination, calculate and
Store PNS and SNS response.In addition, represent stomodaeal nervous system activity value can with to represent parasympathetic movable
Value compares.For example, the value for indicating stomodaeal nervous system activity is resulting divided by the movable value of parasympathetic is represented
Quotient is known as sympathetic vagus nerve balance (SB).This measurement can be the individual for determining subject's autonomic nervous system function
Change measurement.
May alternatively or additionally, signal, which can be captured in real time and be transferred to centralization, calculates facility 14, by the centralization
It calculates the storage of facility 14, analysis, processing or determines PNS, SNS and SB response.Centralization, which calculates facility 14, may include and connects
The server 40 being connected to the network to one or more computers 22 of subject 12 is (for example, work together to retrieve and store number
According to one or more servers 40).Server 40 may include processor 42, memory 44 and be stored in memory 44
In, detect for receiving, analyzing and store from the one or more ANS monitoring systems 18 used by one or more subjects 12
With the instruction of the response of transmission.In addition, server 40 includes by wired connection or by the reception of reception of wireless signals signal
Device 46 allows server 40 to receive signal from remote computer 30.In certain embodiments, receiver 46 may include hair
Emitter and/or transceiver send and receive signal by server 40.
Then the response that can be will test is led to computer 22, server 40 or Local or Remote electronics is for example stored in
Believe that addressable previously determined threshold value elsewhere is compared.Compare the shape that can indicate the nervous system of subject 12
State.In the example of driver above, the response for determining and comparing can indicate that driver has more vigilance or awake.If service
Device 40 determines that the state of subject 12 is fallen into the range that instruction subject 12 may be drowsy or on the line, to lead
Cause may be the event of " compromise state ", then caution signal is sent to subject 12, management entity 16 by central computing facility 14
Or its certain combination.Caution signal may include the audio to subject, video or haptic alerts, and can be to subject 12
Alert compromise state and suggest 12 pulling over observing of subject, rest, fixed time period is waited to rejuvenate etc..In addition,
The combination of computer 22, server 40 or both, which can determine, has occurred that emergency related with subject 12, such as
Syncope or heart attack, in this case, caution signal can suggest that subject 12 seeks medical rescue.If impaired shape
The case where state is related to health problem or driver is likely to occur alcohol or chemical substance or other Substance Intoxications, then caution signal can
It can include notice emergency response personnel or other authorities.If first caution signal is ignored and PNS, SNS of driver
SB response fall into instruction subject 12 sleeping or other dangerous ways in the range of, then can to subject 12 (and
Optionally, management entity 16 or their combination) it sends additional caution signal and attempts to wake up subject 12 and/or second alert
Report can be sent to local authority to enable them to assist driver, such as subject 12.
As another example that how can use system 10, consider that subject 12 is required to handle emergency
Emergency worker (on either land or ship, this is also applied for being command by the soldier for participating in fight).This time, subject 12
It includes position, temperature, perspire level, air quality, pulse wave velocity, SpO that underwear of the dress with sensor, which is collected,2And
The data of EKG and respiratory activity.These signals, which can be captured in real time and be transferred to centralization, calculates equipment 14, by the centralization
It calculates equipment 14 and carries out storage, analysis and the processing of signal, and calculate and store PNS, SNS and SB response.Then by these
Response is compared with the threshold value of previously determined instruction 12 state of subject.Then these instructions can be sent to including prison
Superintend and direct the management entity 16 including the personnel (or the senior officer for participating in fight) of emergency.These can be used in management entity 16
Indicate the level of security to help to maintain subject 12, perhaps determine when to extract subject 12 or provide it is more assist, or
Person provides emergency medical and assists (in this case, instruction identifies classification for the long-range condition of the injury of subject 12).
Computer 22, server 40 or combinations thereof can program come by computer instruction come using side shown in Fig. 2
Method 60 come measure, related and analysis simultaneously and independent PNS, SNS and ANS activity.Due to parasympathetic and sympathetic mind
Through system co-ordination in human body, thus to each system carry out independent measurement be it is beneficial, because even a system or
Another system function is abnormal, and two systems are still run in a coordinated fashion.In addition, being estimated using single physiological measure
The function of stomodaeal nervous system and parasympathetic can cover the abnormal conditions in a system or another system.Just as
Two independent equations must be provided to solve to have the algebra problem of two independent variables the same, need two independent physics
Measured value comes independent present parasympathetic and stomodaeal nervous system.
Method 60 may include the first independent measured levels (box 62) for acquiring physiological activity.The first of physiological activity is independent
Measured value can indicate PNS or SNS or totality ANS activity.For example, including the movable embodiment of SNS in the first independent measured levels
In, the EKG signal or other signals obtained from EKG sensor 24 can be used for assessing SNS.SNS activity can be joined by other
Number is assessed, including but not limited to：Changes in heart rate, micro- neurologic examination, office between blood pressure, pulse wave velocity, heartbeat and heartbeat
Portion's plasma norepinephrine measured value or other measured values.
Method 60 may include the second independent measured levels (box 64) for acquiring body movement.The second of body movement is independent
Measured value can also indicate that SNS or PNS or totality ANS activity.For example, including the movable implementation of SNS in the first independent measured levels
In example, the second independent measured levels may include PNS activity.As a possible example, respiratory activity signal can be used
Assess PNS.PNS activity can be assessed by other parameters, including but not limited to：Heart rate when the dynamic and static breath of stomach and intestine movable becomes
Change and respond changes in heart rate, Wa Er Salva (Valsava) movement, postural change and the face immersion apnea when deeply breathing
(apneic facial immersion) and other measured values.
Then the first independent physiological activity index of acquisition and the signal of the second independent physiological activity index be can analyze, with
Determine the activity of sympathetic nerve and parasympathetic.For each independent measured value, when ANS monitors system 18 or service
Numerical value (box 66, box 68) can be determined when the manipulation measurement of device 40.For example, two signals can be manipulated to calculate two independences
Frequency spectrum.Fig. 3 shows frequency spectrum 80 (such as EKG frequency spectrum, heart rate frequency spectrum, the SNS frequency spectrum of the first independent measured levels of physiological activity
Deng) exemplary embodiment.Frequency spectrum 80 show by ANS monitoring system 18 (and relevant sensor 20) detection with to timing
Between the relevant frequency 82 of frequency 84 in section.For physiological activity the second independent measured levels (for example, PNS frequency spectrum, breathing frequency
Rate frequency spectrum etc.) calculate similar frequency spectrum.ANS monitors system 18 and/or server 40 and will acquire for the first and second measured values
Time carry out related (box 70 of the method 60 of Fig. 2).By the time of correlation acquisition, the first of physiological activity can be used
The frequency spectrum 80 of independent measured levels calculates ANS and relatively movable useful information about subject 12.
As shown in figure 4, the specific peak-mode frequency 86 of the second independent measured levels of physiological activity frequency spectrum can be determined,
Store and be mapped to the frequency spectrum 80 of the first independent measured levels of physiological activity.By the first independent measured levels of physiological activity and
After second independent measured levels carry out correlation, ANS monitoring system 18 or server 40 will compare numerical value (box 72).Numerical value compares can
The area of frequency spectrum 80 is calculated to include the relationship between the first and second independent measured levels about physiological activity.For example, such as
Shown in Fig. 5, frequency spectrum 80 can be used for calculating PNS response in the area of particular range 88.Specified range may include 0.03Hz,
0.04Hz, 0.05Hz, 0.06Hz, 0.07Hz, 0.08Hz or other frequencies measured above and below peak-mode frequency 86
Range.In one embodiment, peak-mode frequency 86 can be measured as 0.19Hz.Specified range can be in peak-mode
0.06Hz on or below frequency 86.Therefore, area of the frequency spectrum 80 between 0.13Hz and 0.25Hz would be equivalent to PNS response.
Specified range 88 can change according to the predetermined characteristic of subject 12, or can keep one for all subjects 12
It causes.
SNS response also can use the calculating of frequency spectrum 80.As shown in fig. 6, ANS monitoring system 18 can program to include SNS
Default scoping 90.For example, In a particular embodiment, default scoping 90 may include the range from 0.04Hz to 0.15Hz.
However, in order to calculate SNS response, it is necessary to remove the frequency 92 Chong Die with the frequency that PNS is responded.Frequency spectrum 80 is in remaining range 94
Area be equal to PNS response.The ratio that sympathetic nerve reaction is reacted with parasympathetic nerve is calculated as sympathetic nerve balance (SB
=S/P), it is used to determine the instantaneous function (box 74) of the autonomic nerves system of subject 12.Sympathetic nerve balance height according to
Rely in individual, and ongoing activity personal at that time.It is applicable in when subject is resting or participating in the activity of more sitting
The sympathetic fan of the static state sympathetic fan of dynamic applicable when will be engaged in more violent activity with subject that walks balance walk balance exist it is obvious
Difference.
The activity of subject 12 when being connected according to monitoring sensor 20, subject 12 are perhaps resting or are participating in living
It is dynamic.If subject 12 is resting, SB is the index for measuring rest balance.If subject's participation activity, SB are
Measure the index of dynamic equilibrium.Then can by from subject these equilibrium responses and previously determined threshold value or range it is (" pre-
Determine range ") it compares, the threshold value or range defines a large amount of modes of operation or health shape for monitored subject
State, state of wellness.When the reaction of subject is in these preset ranges, it can be used for assessing personal healthy shape
Condition, the physical condition for either moving or playing a role in local environment about the health status of s/he or s/he.
Previous method is used for inaccurately being applied to the standard and approximation of many individuals.In addition, by standard
Know from experience applied to autonomic nervous system function abnormal and obtains more inaccurate information.
Two independent physiological measures are converted into instantaneous value, to determine parasympathetic and stomodaeal nervous system
In the function of particular moment.Then, these values are related to time progress, to ensure feasible comparison.Signal can be with a variety of
Mode manipulates.Signal can be filtered, to remove noise, and the data smoothing of acquisition be handled.Then it can will acquire
To data be converted to quantized values, to carry out objective comparison.
Then stomodaeal nervous system and parasympathetic can be measured independently and simultaneously.These functions can carry out phase
It closes and analyzes, to provide the overall picture of autonomic nerves system.Finger of the numerical value as stomodaeal nervous system of instantaneous heart rate can be calculated
Mark.Index of the numerical value as parasympathetic of respiratory rate can be calculated.When the sympathetic fan of calculating walks to balance, can incite somebody to action
It is compared with previously determined or storage the data specific to individual, to indicate the situation of subject.In this way, originally
Invention provides the assessment specific, accurate and personalized to the height of the complete autonomic nerves system of subject.
Although emphasis describes these embodiments, it is understood that, it within the scope of the appended claims, can
To implement these embodiments in a manner of being different from specifically describing herein.
Claims (20)
1. one kind for parasympathetic autonomic nerves system and sympathetic autonomic nerves system while and independent activities measure,
Related and analysis method, including：
The first independent measured levels of physiological activity are acquired from subject, wherein first independent measured levels indicate sympathetic nervous system
System activity or overall Autonomic nervous system activity；
The second independent measured levels of physiological activity are acquired from subject, wherein second independent measured levels indicate parasympathetic nerve
System activity；
The movable numerical value of parasympathetic is determined from second independent measured levels；
Determine the numerical value of stomodaeal nervous system activity from first independent measured levels, or from first independent measured levels and
The numerical value of second independent measured levels combined to determine stomodaeal nervous system activity；
First independent measured levels are related to the progress of the acquisition time of second independent measured levels；
After following the correlation closely, by the numerical value for being used for the stomodaeal nervous system activity of the acquisition time and it is used for described
The movable numerical value of the parasympathetic of acquisition time is compared；And
Determine the instantaneous function of the autonomic nerves system (ANS) of the subject.
2. according to the method described in claim 1, the wherein numerical value of the stomodaeal nervous system activity and the parasympathetic nerve
The numerical value of system activity includes the value obtained from frequency spectrum.
3. according to the method described in claim 1, wherein the first independent measured levels of the physiological activity include exhaling for subject
Movable measured value is inhaled, the second independent measured levels of the physiological activity include the measured value of the heart rate of subject.
4. according to the method described in claim 1, the step of wherein acquiring the second independent measured levels of the physiological activity includes
The heart rate is measured using ECG monitor.
5. according to the method described in claim 1, including：By the instantaneous function of the autonomic nerves system of the subject and make a reservation for
Range be compared.
6. according to the method described in claim 1, further comprising：Electronic signal is sent to administrator, the electronic signal
Indicate the instantaneous function of the autonomic nerves system of the subject.
7. according to the method described in claim 1, further comprising：Instantaneous function based on the autonomic nerves system provides anti-
Feedback.
8. according to the method described in claim 1, the step of wherein acquiring the first independent measured levels of the physiological activity includes
The heart rate is measured using ECG monitor.
9. one kind with independent measured levels for carrying out parasympathetic autonomic nerves system and sympathetic Autonomic nervous system activity simultaneously
Measurement, related and analysis system, including：
First sensor, the first independent measured levels of the physiological activity for acquiring subject；
Second sensor, the second independent measured levels of the physiological activity for acquiring the subject；
Computer, wherein the computer includes：
Computer processor；
Receiver, the second independent measurement of the first independent measured levels and the physiological activity for receiving the physiological activity
Value；And
The data storage media of non-transient, including：Computer instruction is used to indicate the computer processor：
First independent measured levels are related to the progress of the acquisition time of second independent measured levels；
The numerical value of stomodaeal nervous system activity is compared with the movable numerical value of parasympathetic；
Determine the instantaneous function of the autonomic nerves system of the subject.
10. system according to claim 9, wherein the first sensor includes electrocardiography transducer, and described
Two sensors include the sensor for monitoring the breathing pattern of subject.
11. system according to claim 9, further comprises：With the one of the computer Local or Remote network communication
A or multiple servers, wherein one or more of servers include the computer instruction.
12. system according to claim 9, wherein one or more of servers are configured to from monitoring the second subject
Second computer receive the physiological activity the first independent measured levels the second example and the physiological activity second solely
Second example of vertical measured value.
13. system according to claim 9, wherein one or more of servers are configured to notify to close to management entity
In the instantaneous function of the autonomic nerves system of the subject, second subject or described the two.
14. being surveyed while one kind is for parasympathetic autonomic nerves system and sympathetic autonomic nerves system with independent activities
Amount, related and analysis system, including：
First sensor, the first independent measured levels of the physiological activity for acquiring subject；
Second sensor, the second independent measured levels of the physiological activity for acquiring the subject；
Computer, wherein the computer includes：
Computer processor；
Receiver, the second independent measurement of the first independent measured levels and the physiological activity for receiving the physiological activity
Value；And
The data storage media of non-transient, including：Computer instruction is used to indicate the computer processor：
First independent measured levels are related to the progress of the acquisition time of second independent measured levels；
The numerical value of stomodaeal nervous system activity is compared with the movable numerical value of parasympathetic, to determine equilibrium,transient
Measured value；And
The equilibrium,transient measured value is compared with subject with reference to balancing side magnitude, with the autonomous of the determination subject
The instantaneous function of nervous system.
15. system according to claim 14, wherein the computer instruction is programmed to based on the parasympathetic system
Instantaneous function determined by system provides feedback.
16. system according to claim 15, wherein the feedback is mentioned in the form of audio, video or tactile alert alarm
Supply the subject.
17. system according to claim 15, wherein the feedback be provided to positioned at the subject locally or remote from
The management entity of the subject.
18. according to the method for claim 14, further comprising：The clothes of Local or Remote network communication are carried out with computer
Business device.
19. system according to claim 18, wherein one or more of servers be configured as from monitoring second by
The second computer of examination person receives the second example of the first independent measured levels of physiological activity and the second independence of physiological activity
Second example of measured value.
20. system according to claim 18, wherein one or more of servers are configured as leading to management entity
MS is in the instantaneous function of the autonomic nerves system of the subject, second subject or described the two.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/US2015/064695 WO2017099749A1 (en) | 2015-12-09 | 2015-12-09 | Method and system of measurement, correlation, and analysis of simultaneous and independent parasympathetic and sympathetic autonomic nervous system activity |
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| CN108882883A true CN108882883A (en) | 2018-11-23 |
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| CN201580085562.3A Pending CN108882883A (en) | 2015-12-09 | 2015-12-09 | Parasympathetic autonomic nerves system is measured to while sympathetic autonomic nerves system to independent activities, related and analysis method and system |
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| CN (1) | CN108882883A (en) |
| AU (1) | AU2015416686A1 (en) |
| PH (1) | PH12018501232A1 (en) |
| WO (1) | WO2017099749A1 (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113143274A (en) * | 2021-03-31 | 2021-07-23 | 北京晶栈信息技术有限公司 | Emotion early warning method based on camera |
| CN114206209A (en) * | 2019-08-07 | 2022-03-18 | 途倍Dtx株式会社 | Orthostatic hypotension detection system and method using heart rate based machine learning algorithm and wearable measurement device |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPWO2021182249A1 (en) * | 2020-03-11 | 2021-09-16 |
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- 2015-12-09 WO PCT/US2015/064695 patent/WO2017099749A1/en active Application Filing
- 2015-12-09 AU AU2015416686A patent/AU2015416686A1/en not_active Abandoned
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2018
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| CN1698535A (en) * | 2004-05-18 | 2005-11-23 | 香港中文大学 | Method for measuring blood pressure change rate |
| US20060100534A1 (en) * | 2004-07-09 | 2006-05-11 | Ansar, Inc. | Methods for real-time autonomic nervous system monitoring using total heart rate variability, and notched windowing |
| US7711415B1 (en) * | 2006-11-08 | 2010-05-04 | Pacesetter, Inc. | Implantable devices, and methods for use therewith, for monitoring sympathetic and parasympathetic influences on the heart |
| US20130274616A1 (en) * | 2011-11-04 | 2013-10-17 | The Ansar Group Inc. | Electrocardiogram derived respiration signal for parasympathetic and sympathetic monitoring devices |
| CN103892812A (en) * | 2014-02-24 | 2014-07-02 | 南京丰生永康软件科技有限责任公司 | Matching degree analysis technology |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN114206209A (en) * | 2019-08-07 | 2022-03-18 | 途倍Dtx株式会社 | Orthostatic hypotension detection system and method using heart rate based machine learning algorithm and wearable measurement device |
| CN113143274A (en) * | 2021-03-31 | 2021-07-23 | 北京晶栈信息技术有限公司 | Emotion early warning method based on camera |
| CN113143274B (en) * | 2021-03-31 | 2023-11-10 | 中国科学院心理研究所 | Emotion early warning method based on camera |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2017099749A1 (en) | 2017-06-15 |
| PH12018501232A1 (en) | 2019-02-04 |
| AU2015416686A1 (en) | 2018-07-26 |
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