CN108772112A - A kind of capillary device of fixed quantity drain - Google Patents

A kind of capillary device of fixed quantity drain Download PDF

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Publication number
CN108772112A
CN108772112A CN201810584622.1A CN201810584622A CN108772112A CN 108772112 A CN108772112 A CN 108772112A CN 201810584622 A CN201810584622 A CN 201810584622A CN 108772112 A CN108772112 A CN 108772112A
Authority
CN
China
Prior art keywords
capillary
mandril
drain
fixed quantity
screens
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201810584622.1A
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Chinese (zh)
Inventor
白伟
郝曦东
郑先龙
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nanjing Large Tree Biological Medical Technology Ltd By Share Ltd
Original Assignee
Nanjing Large Tree Biological Medical Technology Ltd By Share Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nanjing Large Tree Biological Medical Technology Ltd By Share Ltd filed Critical Nanjing Large Tree Biological Medical Technology Ltd By Share Ltd
Priority to CN201810584622.1A priority Critical patent/CN108772112A/en
Publication of CN108772112A publication Critical patent/CN108772112A/en
Pending legal-status Critical Current

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Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/02Burettes; Pipettes
    • B01L3/021Pipettes, i.e. with only one conduit for withdrawing and redistributing liquids
    • B01L3/0217Pipettes, i.e. with only one conduit for withdrawing and redistributing liquids of the plunger pump type
    • B01L3/022Capillary pipettes, i.e. having very small bore

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  • Health & Medical Sciences (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

The invention discloses a kind of capillary device of fixed quantity drain, including capillary, Nei Sai and mandril, the interior plug is arranged in the capillary, and the mandril controls the movement of the interior plug, and the mandril is provided with multiple screens.The capillary device of the fixed quantity drain of the present invention, by plug in being arranged in capillary, using the movement filled in mandril control, and using screens control drain number and lifting rate, to realize fixed quantity drain.

Description

A kind of capillary device of fixed quantity drain
Technical field
The present invention relates to a kind of capillary devices of fixed quantity drain.
Background technology
It is carried out using a small amount of finger tip tip blood specimen with being constantly progressive for quick detection means in field of medical examination Quantitatively the detection product of detection Multiple biomarkers is gaining popularity application, such as the detection of blood glucose or blood fat project.When detection, sample-adding Whether amount is accurately one of whether accurate key factor of testing result.Traditional quantitative capillary is indicated often through scribing line inhales sample Volume, accuracy is poor, and operator is not easy to accurately control suction amount.Also, need to squeeze matching used suction nozzle when drain Blood can be excluded, capillary tube inner wall blood residuals are more, are difficult to control, and it is inaccurate to will also result in lifting rate.
Meanwhile with the development of new science and technology, more and more entry (or multisample) joint-detection test paper gradually list, Such as blood fat entry joint-detection test paper (card) product, blood glucose/blood fat joint-detection test paper (card) product, blood glucose/uric acid connection Close Test paper (card) product, glutamic-pyruvic transaminase/glutamic-oxalacetic transaminease joint-detection test paper (card) product, glutamic-pyruvic transaminase/blood red Albumen joint-detection test paper (card) product etc., wherein many products are required for repeatedly healing the detection that could complete whole projects. Must repeatedly be sucked blood using conventional capillary, multiple drain could be completed to be loaded, cumbersome and accuracy is bad, easy residual.
Therefore, it is necessary to a kind of capillary devices of fixed quantity drain to solve the above problems.
Invention content
The technical problem to be solved in the present invention is to provide one kind can a quantitative liquid suction and fixed quantity drain hair Pipette device.
In order to solve the above-mentioned technical problem, the technical solution that the capillary device of fixed quantity drain of the invention uses is such as Under.
A kind of capillary device of fixed quantity drain, including capillary, Nei Sai and mandril, the interior plug are arranged described In capillary, the mandril controls the movement of the interior plug.
Further, one end of the capillary is provided with direction signs line.Facilitate prompt user by mandril from band Capillary is stretched into one end of direction signs line.
Further, it is provided at least one screens on the mandril.It can facilitate and be realized using at least one screens Quantitative drain.
Further, there are two screens for setting on the mandril.It can facilitate quantitative twice using two screens realizations Drain.
Further, the outer diameter of the screens is more than the internal diameter of the capillary.When touching capillary so as to screens, Effectively mandril can be prevented further to push within certain limits.
Further, it is provided with air hole beyond the Great Wall in described.It is inside provided with air hole beyond the Great Wall facilitates and is inhaled using capillary Blood, air can penetrate, but when blood fills up air hole, then stop sucking blood, the reason is that interior plug air hole is no longer ventilative, hair Thin event resolves.The preferred hydrophobic, air-permeability material of material of interior plug.
Further, the inner wall of the interior plug and the capillary is interference fitted.The inner wall interference of interior plug and capillary Cooperation facilitates, and liquid in capillary is discharged using the movement of interior plug.
Further, when drain, the capillary is stretched into one end of the mandril.
Further, the every capillary is equipped with one or more corresponding mandril.The rule of more mandrils Lattice are different, then can realize that various ways quantify drain by the mandril of more different sizes.
Further, it is provided at least one lasso on the mandril.It is sleeved on mandril using lasso and realizes screens Effect.
Further, it is provided with graduation mark on the mandril.Facilitate the quantitative drain of realization using graduation mark.
Advantageous effect:The capillary device of the fixed quantity drain of the present invention is utilized by plug in being arranged in capillary The movement filled in mandril control, and using screens control drain number and lifting rate, to realize fixed quantity drain.
Description of the drawings
Fig. 1 is the structural schematic diagram of the capillary device of the fixed quantity drain of the present invention;
Fig. 2 is the structural schematic diagram of interior plug;
Fig. 3 is the schematic diagram that mandril is inserted into application method;
Fig. 4 is the schematic diagram of a drain in application method;
Fig. 5 is the schematic diagram of secondary drain in application method.
Specific implementation mode
It is hereafter for the embodiment cooperation attached drawing mode embodiment that is described in detail, but is provided not limiting this The covered range of invention, and the description of structure operation is non-to limit the sequence of its execution, it is any to be reconfigured by component Structure, it is produced that there is equal and other effects device, it is all the range that the present invention is covered.
Please refer to Fig.1 with shown in Fig. 2, the capillary device of fixed quantity drain of the invention, including capillary 1, it is interior plug 2 With mandril 3, interior plug 2 is arranged in capillary 1, and mandril 3 controls the movement of interior plug 2.Wherein, 1 preferred capillary glass tube of capillary.
Preferably, one end of capillary 1 is provided with direction signs line 11.Facilitate prompt user by mandril from direction sign Capillary is stretched into the one end for knowing line.
Preferably, it is provided at least one screens 31 on mandril 3.It can facilitate and realize quantitative row using at least one screens Liquid.Tool is please referred to Fig.1 with shown in Fig. 2, specifically, being arranged on mandril 3, there are two screens 31.It can facilitate and utilize two screens realities Drain is now quantified twice.Wherein, the screens 31 on mandril 3 can be, but not limited to by 3 corresponding position spherical mandrill 3 of mandril, It causes the mode of 3 local deformation of mandril to be arranged, can also be set to screens 31 by stickup, hot melt or ultrasonic bonding mode On mandril 3.
Preferably, it is provided with air hole on interior plug 2.It is inside provided with air hole beyond the Great Wall facilitates and is sucked blood using capillary, air It can penetrate, but when blood fills up air hole, then stop sucking blood, reason is that interior plug air hole is no longer ventilative, capillarity It disappears.The preferred hydrophobic, air-permeability material of material of interior plug.The inner wall of interior plug 2 and capillary 1 is interference fitted.Interior plug is interior with capillary Wall interference fit facilitates, and liquid in capillary is discharged using the movement of interior plug.Wherein, the outer diameter of screens 31 is more than capillary 1 Internal diameter.The outer diameter of screens 31 should be slightly bigger than the internal diameter of capillary 1, can be in certain limit when touching capillary so as to screens Interior effective prevention mandril further pushes.Wherein, mandril and screens should have some strength and have certain elasticity concurrently, convenient for firmly Plug movement in pushing, screens width are slightly larger than capillary inner diameter, but after enforcing extruding, should be able to slightly deform so as to smooth Into inside capillary.The preferred glass fibre of material, PE, PP etc..
Preferably, when drain, capillary 1 is stretched into one end of mandril 3.
Preferably, it is equipped with one or more corresponding mandril 3 per capillary 1.The specification of more mandrils is respectively not It is identical, then it can realize that various ways quantify drain by the mandril of more different sizes.
Preferably, it is provided at least one lasso on mandril 3.The effect that screens is realized on mandril is sleeved on using lasso.Top It is provided with graduation mark on bar 3.Facilitate the quantitative drain of realization using graduation mark.And the combination of graduation mark and lasso is utilized, Wo Menke Very easily to realize arbitrarily quantitative screens setting.Wherein, lasso can be rubber ring or elastic ring etc., by being sleeved on mandril Specific position forms screens on 3.
Inventive principle:The installation site of the internal diameter of capillary 1 and interior plug 2 is used to control the liquid absorption amount of capillary.On mandril 3 The number of the quantity control drain of screens 31.The position of screens 31 and spacing control each lifting rate.
Embodiment one:
It please refers to Fig.1 with shown in Fig. 2, fixed quantity drain capillary device of the invention includes capillary 1,2 and of interior plug Mandril 3.Containing interior plug 2 in capillary 1, and it is equipped with direction signs line 11.The screens 31 containing there are two on mandril 3, to control two The volume of secondary drain.
Capillary 1 selects high-boron-silicon glass capillary, internal diameter 1.5mm, length 75mm;2 1.50~1.55mm of diameter of interior plug, Length 3mm, material are hydrophobic, air-permeability material, Nei Sai and capillary front end distance 34mm, total imbibition volume (V=π r2× h) it is 60 μl;3 length of mandril is 73mm;There are two screens 31, is located at the end of mandril, is spaced 17mm.Specifically, first screens 31 At away from 3 front end 55mm of mandril, second screens 31 is located at away from 3 front end 72mm of mandril, spacing 17mm.
It please refers to shown in Fig. 3, Fig. 4 and Fig. 5,
Application method:
1, prepare:
A capillary and a mandril are taken out from Packaging Bottle;
2, lancing:
By " aculeus blood-taking " related request, needle pierces examinee's finger tip;
3, it sucks blood:
After flowing out part blood, by capillary front end close to blood, blood is sucked in capillary through capillary action, directly It is drawn to interior piston part position to blood, can be automatically stopped to suck blood (can voluntarily block interior plug air hole, capillarity in blood infiltration after plug It disappears).Pipette is 60 μ l.
4, it is inserted into mandril
Capillary leaves finger tip, and mandril insertion capillary (is plugged in mandril front end along capillary direction signs line one end Enter in capillary), until mandril gently touches interior plug.
5, drain:
Capillary front end is directed at joint-detection test paper or the one of well of card, another hand slowly push mandril, Blood is discharged, until mandril first " screens " is stuck in capillary end, stops pushing mandril immediately after meeting obstructions, and remove Capillary.First time lifting rate is 30 μ l.
6, secondary drain:
Capillary front end is directed at joint-detection test paper or blocks another well, and will be firmly by first " card of mandril Inside the push-in capillary of position ", and continue to push mandril until second " screens " is stuck in capillary end.Sample-adding is completed, and is removed Capillary.Second of lifting rate is 30 μ l.
Quantitative drain capillary application notice:
1, quantitative drain capillary should be used by prescribed direction, must not reversely be used.
2, quantitative drain capillary is Glass breadks easily article, should be handled with care.
3, plug position determines imbibition volume in quantitative drain capillary, must gently contact interior plug when being packed into mandril, no To " drain " step, interior plug can't be moved.
4, mandril " screens " diameter is slightly larger than capillary inner diameter, and when drain should slowly push mandril, once it meets obstructions (i.e. " screens " is stuck in capillary end) it should just stop pushing immediately, in order to avoid screens is pushed into capillary, cause first time drain Amount.
5, quantitative drain capillary clean should be kept, must not be polluted.
6, quantitative drain capillary is one-off, should be handled by " clinical waste " after use.
The capillary device of the fixed quantity drain of the present invention is controlled by plug in being arranged in capillary using mandril The movement of interior plug, and using screens control drain number and lifting rate, to realize fixed quantity drain.

Claims (10)

1. a kind of capillary device of fixed quantity drain, it is characterised in that:Including capillary (1), interior plug (2) and mandril (3), Interior plug (2) setting is in the capillary (1), the movement of mandril (3) the control interior plug (2).
2. the capillary device of fixed quantity drain as described in claim 1, it is characterised in that:The one of the capillary (1) End is provided with direction signs line (11).
3. the capillary device of fixed quantity drain as described in claim 1, it is characterised in that:It is arranged on the mandril (3) There is at least one screens (31).
4. the capillary device of fixed quantity drain as described in claim 1, which is characterized in that be arranged on the mandril (3) There are two screens (31).
5. the capillary device of fixed quantity drain as claimed in claim 3, it is characterised in that:The outer diameter of the screens (31) More than the internal diameter of the capillary (1).
6. the capillary device of fixed quantity drain as described in claim 1, it is characterised in that:It is arranged on the interior plug (2) There is air hole.
7. the capillary device of fixed quantity drain as described in claim 1, it is characterised in that:The interior plug (2) with it is described The inner wall of capillary (1) is interference fitted.
8. the capillary device of fixed quantity drain as described in claim 1, it is characterised in that:When drain, the mandril (3) One end stretch into the capillary (1).
9. the capillary device of fixed quantity drain as described in claim 1, it is characterised in that:The every capillary (1) It is equipped with one or more corresponding mandril (3).
10. the capillary device of fixed quantity drain as described in claim 1, it is characterised in that:It is arranged on the mandril (3) There is at least one lasso.
CN201810584622.1A 2018-06-06 2018-06-06 A kind of capillary device of fixed quantity drain Pending CN108772112A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201810584622.1A CN108772112A (en) 2018-06-06 2018-06-06 A kind of capillary device of fixed quantity drain

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201810584622.1A CN108772112A (en) 2018-06-06 2018-06-06 A kind of capillary device of fixed quantity drain

Publications (1)

Publication Number Publication Date
CN108772112A true CN108772112A (en) 2018-11-09

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Family Applications (1)

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CN201810584622.1A Pending CN108772112A (en) 2018-06-06 2018-06-06 A kind of capillary device of fixed quantity drain

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Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1071506A (en) * 1965-05-11 1967-06-07 Ernest Frederick Dawes Measuring syringe
JP2006239260A (en) * 2005-03-07 2006-09-14 Hakko Co Ltd Medical solution syringe device
GB201112347D0 (en) * 2011-07-18 2011-08-31 Rajah Shantal An improved syringe
JP2014028081A (en) * 2012-07-31 2014-02-13 Yoshino Kogyosho Co Ltd Quantitative syringe type ejection device
WO2014162551A1 (en) * 2013-04-04 2014-10-09 テルモ株式会社 Syringe
CN204134656U (en) * 2014-10-21 2015-02-04 厦门市科环海洋生物科技有限公司 A kind of sample injector of continuous and quantitative
CN204521829U (en) * 2015-03-17 2015-08-05 李芹 A kind of fixed-quantity injector
US20160144356A1 (en) * 2013-06-17 2016-05-26 Waters Technologies Corporation Micropipet for aliquoting small volumes of fluid
CN208727528U (en) * 2018-06-06 2019-04-12 南京大树生物医疗技术股份有限公司 A kind of capillary device of fixed quantity drain

Patent Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1071506A (en) * 1965-05-11 1967-06-07 Ernest Frederick Dawes Measuring syringe
JP2006239260A (en) * 2005-03-07 2006-09-14 Hakko Co Ltd Medical solution syringe device
GB201112347D0 (en) * 2011-07-18 2011-08-31 Rajah Shantal An improved syringe
JP2014028081A (en) * 2012-07-31 2014-02-13 Yoshino Kogyosho Co Ltd Quantitative syringe type ejection device
WO2014162551A1 (en) * 2013-04-04 2014-10-09 テルモ株式会社 Syringe
US20160144356A1 (en) * 2013-06-17 2016-05-26 Waters Technologies Corporation Micropipet for aliquoting small volumes of fluid
CN204134656U (en) * 2014-10-21 2015-02-04 厦门市科环海洋生物科技有限公司 A kind of sample injector of continuous and quantitative
CN204521829U (en) * 2015-03-17 2015-08-05 李芹 A kind of fixed-quantity injector
CN208727528U (en) * 2018-06-06 2019-04-12 南京大树生物医疗技术股份有限公司 A kind of capillary device of fixed quantity drain

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