CN108720814A - A kind of Breast health remote supervision system and method - Google Patents
A kind of Breast health remote supervision system and method Download PDFInfo
- Publication number
- CN108720814A CN108720814A CN201810915953.9A CN201810915953A CN108720814A CN 108720814 A CN108720814 A CN 108720814A CN 201810915953 A CN201810915953 A CN 201810915953A CN 108720814 A CN108720814 A CN 108720814A
- Authority
- CN
- China
- Prior art keywords
- breast
- temperature
- data
- user
- wearable device
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/01—Measuring temperature of body parts ; Diagnostic temperature sensing, e.g. for malignant or inflamed tissue
- A61B5/015—By temperature mapping of body part
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/0002—Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network
- A61B5/0004—Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network characterised by the type of physiological signal transmitted
- A61B5/0008—Temperature signals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/43—Detecting, measuring or recording for evaluating the reproductive systems
- A61B5/4306—Detecting, measuring or recording for evaluating the reproductive systems for evaluating the female reproductive systems, e.g. gynaecological evaluations
- A61B5/4312—Breast evaluation or disorder diagnosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
- A61B5/6801—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be attached to or worn on the body surface
- A61B5/6802—Sensor mounted on worn items
- A61B5/6804—Garments; Clothes
- A61B5/6805—Vests
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
- A61B5/6801—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be attached to or worn on the body surface
- A61B5/6813—Specially adapted to be attached to a specific body part
- A61B5/6823—Trunk, e.g., chest, back, abdomen, hip
Abstract
The present invention provides a kind of Breast health remote supervision system and method, which includes:Wearable device, remote monitoring server and remote equipment;Wherein, the wearable device, the physiological data for detecting wearable device user's breast, and the physiological data is uploaded to the remote monitoring server;The remote monitoring server, it is communicated to connect with the wearable device, after receiving and storing the physiological data that the wearable device uploads, judges whether the breast of the user is abnormal based on the physiological data, will determine that result is sent to the remote equipment;Remote equipment is communicated to connect with the remote monitoring server, for checking the judging result.Breast health remote supervision system wearable device provided by the invention carries out stealthy active detecting breast physiological data in real time to the physiological data of user's breast, sees a doctor in abnormal constantly remind in time of user's breast.
Description
Technical field
The present invention relates to monitoring technical fields, more particularly to a kind of Breast health remote supervision system and method.
Background technology
In recent years, breast cancer has become the kinds of tumor for threatening women physical and mental health.Although mammary gland is not to maintain human body life
Movable vitals are ordered, but since breast cancer cell loses the characteristic of normal cell, connects loosely, is easy de- between cell
It falls.Cancer cell once falls off, and free cancer cell can send out whole body with blood or lymph, forms transfer, threat to life.It is right
In the mammary gland disease without apparent pain symptom early diagnosis mainly by checking oneself or hospital being gone to be checked by medical staff, but
It is to be required to itself actively, if due to not feeling swollen breasts or other apparent feelings usually, may can't causes
Itself pay attention to.Therefore, it now needs in the case where women itself does not recognize, it is helped to carry out early stage to udder health situation
Detection, to protect female breast healthy.
Invention content
In view of the above problems, it is proposed that the present invention overcoming the above problem in order to provide one kind or solves at least partly
State a kind of Breast health remote supervision system and method for problem.
According to an aspect of the invention, there is provided a kind of Breast health remote supervision system, including:Wearable device,
Remote monitoring server and remote equipment;Wherein,
The wearable device, the physiological data for detecting wearable device user's breast, and by the physiology number
According to being uploaded to the remote monitoring server;
The remote monitoring server is communicated to connect with the wearable device, wearable described in simultaneously typing for receiving
The physiological data that equipment uploads;
Remote equipment is communicated to connect with the remote monitoring server, for calling the remote monitoring server to store
Physiological data, and analysis is managed to the physiological data, to obtain the Breast health situation of the user.
Optionally, the wearable device includes:
With the chest support of wearable device user's breast contact setting, including left chest support and/or right chest support;
It is set at least one of the left chest support and/or the right chest support temperature monitoring unit, supervised with the temperature
Survey the microprocessor of cell data connection;Wherein,
The data monitoring cell distribution is left and right for detecting the user in the left chest support and/or right chest support
The temperature data of breast;
The microprocessor, the temperature data for receiving the temperature monitoring unit transmission are recorded.
Optionally, the wearable device further includes:Wireless communication unit, it is direct or indirect with the microprocessor data
Connection is communicated to connect for being established with the remote monitoring server, and the physiological data of the microprocessor records is transmitted
To the remote monitoring server.
Optionally, the system also includes:Host and router;
The host is connect with the wireless communication unit in the wearable device, single for receiving the wireless communication
The physiological data of member transmission;
Wherein, application management software is provided in the host, the host will be described by the application management software
Physiological data is transmitted to the router by wired or wireless connection;
The router will be described after the physiological data of application management software transmission in receiving the host
Remote monitoring server described in physiological data typing.
Optionally, application software is provided in the remote equipment, the remote equipment is additionally operable to soft using the application
Part carries out administrative analysis by the physiological data of remote monitoring server typing described in socket communications access.
Optionally, the remote equipment is additionally operable to, and is sent control instruction to the wearable device, wearable is set by described
It is standby that detection is started according to the control instruction, stops detection and/or suspend mode.
Optionally, the temperature monitoring unit is set in flexible substrate, based on the flexible substrate and the user
Breast contact;
The temperature monitoring unit includes:Infrared temperature monitoring unit, temperature sensing monitoring unit and/or Non-ionizing radiation
Monitoring unit.
Optionally, the wearable device is further used for:
The quantity of the temperature monitoring unit is customized according to the breast temperature related parametric of the user;And in institute
State temperature monitoring unit be it is multiple when, multiple temperature monitoring cell-averages are distributed in flexible substrate, by described soft
Property substrate be set in the left chest support and/or the right chest support and with described with wearable device user's breast contact.
Optionally, the remote monitoring server is additionally operable to:
Individual database is created for the user, the temperature data that the wearable device transmits is stored to described
Personal data library.
Optionally, the remote equipment is additionally operable to:
Default grader is inputted after calling the remote monitoring server storage temperature data, is known by the default grader
The not described temperature data is normal temperature data and/or abnormal temperature data, and exports recognition result;
Wherein, the default grader is based on healthy breast temperature data, the determining breast temperature number with mammary gland disease
According to this and the doubtful breast temperature training with mammary gland disease obtains.
Optionally, the remote equipment is additionally operable to:
The temperature data of at least one temperature monitoring unit transmission in the remote monitoring server designated time period is called,
Calculate the average temperature value of each temperature monitoring unit in the designated time period;
Obtain the coordinate data of the relatively described user's breast of each temperature monitoring unit, based on the coordinate data with
And corresponding average temperature value draws the temperature pattern of user's breast;Wherein, the coordinate data includes:Make with described
The distance in the horizontal and vertical direction of user's nipple.
Optionally, the remote monitoring server, is additionally operable to:When the breast for judging the user based on the physiological data
When room sends abnormal, alarm signal is sent.
According to another aspect of the present invention, a kind of Breast health remote monitoring method is additionally provided, applied to by that can wear
The Breast health remote supervision system for wearing equipment, remote monitoring server and remote equipment composition, the method includes:
Control wearable device detects the physiological data of the wearable device user breast;
The physiological data of typing wearable device transmission is simultaneously stored, and the part life of remote monitoring server storage is called
Data are managed, and analysis is managed to physiological data, to obtain the Breast health situation of user.
It is long-range in Breast health provided by the invention the present invention provides a kind of Breast health remote supervision system and system
In monitoring system, long-range monitoring clothes are uploaded to after the physiological data of wearable device user's breast is detected by wearable device
Business device carries out typing so that remote equipment calls at any time, and then to the breast physiological data of user by remote monitoring server
It is managed analysis, obtains the Breast health situation of user.In embodiments of the present invention, it is set by using easily wearable
The standby physiological data to user's breast carries out stealthy detection, can be obtained in user meeting the while of dressing primary demand
Active detecting breast physiological data in the case that itself can not discover, has when judging that user may have Breast health hidden danger
Effect auxiliary user pinpoints the problems in time, and then timely medical check.
Above description is only the general introduction of technical solution of the present invention, in order to better understand the technical means of the present invention,
And can be implemented in accordance with the contents of the specification, and in order to allow above and other objects of the present invention, feature and advantage can
It is clearer and more comprehensible, below the special specific implementation mode for lifting the present invention.
According to the following detailed description of specific embodiments of the present invention in conjunction with the accompanying drawings, those skilled in the art will be brighter
The above and other objects, advantages and features of the present invention.
Description of the drawings
By reading the detailed description of hereafter preferred embodiment, various other advantages and benefit are common for this field
Technical staff will become clear.Attached drawing only for the purpose of illustrating preferred embodiments, and is not considered as to the present invention
Limitation.And throughout the drawings, the same reference numbers will be used to refer to the same parts.In the accompanying drawings:
Fig. 1 is Breast health remote supervision system structural schematic diagram according to the ... of the embodiment of the present invention;
Fig. 2 is wearable device structural schematic diagram according to the ... of the embodiment of the present invention;
Fig. 3 is Breast health remote supervision system structural schematic diagram according to the preferred embodiment of the invention;
Fig. 4 is breast temperature pattern according to the ... of the embodiment of the present invention;And
Fig. 5 is Breast health remote monitoring method flow diagram according to the ... of the embodiment of the present invention.
Specific implementation mode
The exemplary embodiment of the disclosure is more fully described below with reference to accompanying drawings.Although showing the disclosure in attached drawing
Exemplary embodiment, it being understood, however, that may be realized in various forms the disclosure without should be by embodiments set forth here
It is limited.On the contrary, these embodiments are provided to facilitate a more thoroughly understanding of the present invention, and can be by the scope of the present disclosure
Completely it is communicated to those skilled in the art.
Fig. 1 is Breast health remote supervision system structural schematic diagram according to the ... of the embodiment of the present invention, as shown in Figure 1, this hair
The Breast health remote supervision system that bright embodiment provides may include:Wearable device 1, remote monitoring server 3 and remote
End equipment 3;Wherein,
Wearable device 1, the physiological data for detecting wearable device user's breast, and physiological data is uploaded to
Remote monitoring server 2;
Remote monitoring server 2 is communicated to connect with wearable device 1, for receiving the simultaneously upload of typing wearable device 1
Physiological data;
Remote equipment 3 is communicated to connect with remote monitoring server 2, the physiology for calling remote monitoring server 2 to store
Data, and analysis is managed to above-mentioned physiological data, to obtain the Breast health situation of user.
An embodiment of the present invention provides a kind of Breast health remote supervision systems, are detected by wearable device 1 wearable
Remote monitoring server 2 is uploaded to after the physiological data of equipment user breast, by remote monitoring server carry out typing for
Remote equipment calls at any time, and then is managed analysis to the breast physiological data of user, obtains the Breast health of user
Situation.In embodiments of the present invention, the physiological data of user's breast is carried out by using convenient wearable device 1 stealthy
Detection can obtain the active detecting breast in the case where user itself can not discover meeting the while of dressing primary demand
Physiological data, to be uploaded to remote monitoring server 2 in time to judge user's Breast health situation, when judgement uses
Person may have mammary gland there are effectively auxiliary user pinpoints the problems in time when risk, and then timely medical check.It can wear
When wearing equipment 1 to the upload physiological data of remote monitoring server 2, it can upload in real time, it can also be according on period specified time
It passes, the present invention does not limit.
Fig. 2 shows wearable device structural schematic diagrams according to the preferred embodiment of the invention, as shown in Fig. 2, wearable
Equipment 1 may include:With the chest support 110 of wearable device user's breast contact setting, including left chest support 111 and/or right chest
Support 112;It is set at least one of left chest support 111 and/or right chest support 112 temperature monitoring unit 120 and temperature monitoring unit
The microprocessor 130 of 120 data connections;Wherein, temperature monitoring unit 120 is distributed in left chest support 111 and/or right chest support 112,
Temperature data for detecting the left and right breast of user, and above-mentioned temperature data is transmitted to microprocessor 30;Microprocessor
130, the temperature data that each temperature monitoring unit 120 transmits can be received and recorded.Only temperature is diagrammatically illustrated in figure
The quantity of monitoring unit 120, the quantity of temperature monitoring unit 120 can be arranged by User Defined in practical application, and the present invention is not
It limits.
Wearable device 1 in the embodiment of the present invention can be also used for being customized according to the breast temperature related parametric of user
The quantity of the temperature monitoring unit.Microprocessor 130 is preferentially set among left chest support 111 and/or right chest support 112, with micro-
Processor 130 is a plurality of branch that starting point has multiple catheters composition, when temperature monitoring unit 120 is multiple, Duo Gewen
Degree monitoring unit 120 is spaced apart in each branch.Multiple temperature monitoring units 120 can also be combined into the array of multinode,
Wearable device 1 can also include flexible substrate, can flexible setting in left chest support 111 and/or right chest support 112;It is supervised in temperature
When survey unit 120 is multiple, multiple data monitoring units 120 are evenly distributed in flexible substrate, and is set by flexible substrate
It is placed in left chest support 111 and/or right chest support 112, with wearable device user's breast contact.Wherein, leading for each branch is connected
Pipe is preferably flexible conduit.
When data monitoring unit 120 being arranged on flexible substrates, can be distributed in by preset rules can be with user's breast
In the flexible substrate of contact.Flexible substrate can be used flexible material and be made, for example, polyvinyl alcohol, polyester, polyimides, poly- naphthalene
Diformazan preparing ethylene glycol, the scraps of paper, textile material.Flexible substrate has good flexibility, ductility, even can only be bent even
It folds, and structure type is flexible and varied, adaptive change, energy can be carried out according to the shape size of the left and right breast of user
It is enough that very easily user's breast is measured.Temperature monitoring unit 120 in the embodiment of the present invention is preferably infrared temperature
Spend monitoring unit, temperature sensing monitoring unit or Non-ionizing radiation monitoring unit.
Wherein, temperature sensing monitoring unit may include the metallic film as thermistor;When user's skin of breast
When external temperature changes, makes metallic film that physical deformation occur and the resistance value of metallic film is caused to change, utilize gold
The resistance value for belonging to film is converted to temperature value, is read at any time by microprocessor 130.Temperature monitoring unit 120 can also be preferably warm
Spend sensor, infrared sensor etc..
Wherein, thermistor can be prepared preferentially using metallic film, such as platinum film.Preparing metallic film process
In, if prepared metallic film has certain resistance value, need to control its film thickness, as a kind of preferred implementation side
Metallic film can be designed as multiple end to end strips, to be set in flexible substrate by formula.
When growth of tumour cell or constantly division, the blood flow in this region will become faster.Blood flow increases so that skin
Skin temperature increases.Therefore, flexible sensor can also be further used for customizing temperature according to the breast temperature related parametric of user
Spend the quantity of monitoring unit;And when temperature monitoring unit is multiple, multiple temperature monitoring cell-averages are distributed in flexibility
On substrate.The temperature of multiple positions of user's breast can be surveyed using flexible sensor provided in an embodiment of the present invention
Amount, can be according to user's own physiological data customization temperature monitoring list when flexible substrate is laid out temperature monitoring unit
The quantity of member, if breast is easy the position of bearing tumor, user's age, weight, family history of breast cancer, drug service condition, more
Term etc..Being measured to user's breast temperature by temperature monitoring unit in this implementation power may only predict whether have
The possibility of breast cancer finds the early stage sign of breast cancer, and dependent makes a definite diagnosis breast cancer.
Preferably, temperature monitoring unit can utilize silicon integrated package, thermoelectricity occasionally to have positive thermal coefficient and bear hot coefficient
Thermistor detects the temperature data of user's breast external skin, and the temperature data of breast external skin is sent to micro- place
Reason device 130 is recorded;Temperature monitoring unit is radially distributed centered on user's nipple.
Non-ionizing radiation monitoring unit can be microwave radiation monitoring unit, and microwave radiation monitoring unit includes multiband spoke
Meter is penetrated, for sending radiated wave to user's breast with specified time frequency, lesion locations temperature is slightly above normal surrounding tissue
The frequency of temperature, back wave carries out discrete different from the frequency of surrounding tissue back wave by collection back wave and to back wave
Fourier transformation can conclude that out that subcutaneous tissue is abnormal.Specifically, radiated wave has corresponding reflection after tissue
The temperature of wave, abnormal structure can be higher than surrounding normal tissue, may result in corresponding reflection wave frequency and signal time delay becomes
Change, temperature phase is learnt by the method for the frequency utilization discrete Fourier transform of reflection obtains the distribution of temperature field energy spectrum
To size, abnormal structure is obtained using the method for carrying out cross-correlation search signal relevant peaks with female wave by the signal time delay of reflection
Position.
Wherein, it is provided with wearable textiles antenna in multiband radiometer, such as circular polarisation ultra wide band wearable textiles antenna,
It is more to distinguish using the electromagnetic property and different form of presentation of different fabrics on the influence of the performance of antenna and Antenna Impedance Matching
The frequency of wave band radiometer prevents the frequency of None- identified abnormal structure back wave.Specifically can according to the electromagnetic property of fabric and
Weaving manner controls the impedance of antenna, length, propagation characteristic.In multiband radiometer, the frequency of transmitted wave is fixed,
And the frequency of back wave will produce different frequency responses according to tissue abnormalities, so according to the most basic surface of artificial magnetic conductor
The characteristic of wavestrip gap and reflected phase band gap then uses the windmill-shaped dipole antenna in broadband, to certain bandwidth frequency range
Signal can receive, and by using the Antenna Design, be directed to skin and operation is directly optimized.
Lump is also one of the symptom that breast cancer may have in breast, typically takes place in the outer top of mammary gland.It is especially right
For adult women, lump should attract great attention in breast.Lump morphological differences is larger, it is considered that form is not advised
Then, blur margin is clear, texture is too hard.Carcinous lump is being limited in early days in mammary gland essence, still pushes, but not like benign tumour
There is larger mobility like that, once invading fascia or skin, lump cannot push, stadium also falls within later.Therefore, in addition to making
The temperature of user's breast can also be detected the lump that user's breast is likely to occur outside being detected.
Optionally, above-mentioned data monitoring unit 120 can also include stress monitoring unit, such as strain gauge, for
User's breast applies stress, and records the initial strain amount of user's breast;And continue to monitor user's breast in real time
Dependent variable, and dependent variable is transmitted to microprocessor list 130.
That is, strain gauge can be to test user's breast for applying stress, and user is detected simultaneously
Breast is for dependent variable caused by the stress, since lump in breast can influence response value of the breast to strain gauge, concurrently
It send to microprocessor 130.Therefore, when first used, the initial strain amount that can first obtain user's breast after this can
To obtain the different dependent variable of survey person's breast with specific frequency, infer whether generated inside mammary gland according to the dependent variable of different times
Lump, and then judge whether to have and to form tumour or cancer.
Mentioned above, it is uncertain that the position of lump is generated in user's mammary gland, and therefore, flexible sensor is further used
In the quantity for customizing strain gauge according to the breast stress relevant parameter of user;And when strain gauge is multiple,
Multiple strain gauges are distributed in flexible substrate respectively by the difference of stress response dynamics.Multiple strain gauges are set
When, the quantity of strain gauge can be customized according to the easy growth position of physiological characteristic or breast lump of user.The stress mornitoring
Device can be foil gauge or other have the device of above-mentioned function, and the embodiment of the present invention does not limit.
In the issuable symptom of breast cancer, nipple discharge is also one of which.Nipple liquid can be physiological or disease
Rationality, the nipple discharge incidence of non-pregnant nursing period is about 3%~8%, the color of discharge can be colourless, milky,
Faint yellow, brown, courage and uprightness etc. also can be in water sample, blood sample, slurries sample purulence;Discharge amount is the amount doesn't matter, and interval time also differs
Sample, general patients with terminal discharge is than more serious.
In a preferred embodiment of the invention, data monitoring unit 120 can also include humidity sensor, to detect user
The humidity value of skin of breast changes.Wherein, humidity sensor includes mainly dew cell, and user's breast is monitored in real time for continuing
The humidity value of head, and humidity value is transmitted to microprocessor 30 and is recorded.Humidity sensor is mainly distributed and user's nipple
Around, the humidity value for continuing monitoring user's nipple in real time, and humidity value is transmitted to microprocessor 130 and is recorded.
Wearable device provided in this embodiment can also include battery (being not shown), battery and microprocessor
130 electrical connections, for powering to microprocessor 130.By the way that battery is arranged, the groundwork of microprocessor 130 can be maintained, the electricity
Pond can be rechargeable battery, when battery capacity is finished, can charge to it.In addition to this it is possible in wearable device
Charge port is set, is directly charged to battery by the charge port, further, DC power supply can also be set in wearable device
Connector, to be directly connected to DC power supply.
In a preferred embodiment of the invention, wearable device 1 can also include:Wireless communication unit (does not show in figure
Go out), it with 130 data direct or indirect connection of microprocessor, is electrically connected with battery, for wirelessly being connected with external equipment
It connects, the physiological data that microprocessor 130 records is transmitted to remote monitoring server 2.Wireless communication unit can also basis
User demand is disposed at the heart position 113 of wearable device 1, or is arranged at other positions of wearable device, and the present invention is not
It limits.Preferably, wifi module or bluetooth module with wireless communication function are also integrated on microprocessor 130.
As shown in figure 3, the Breast health remote supervision system of the preferred embodiment of the present invention, can also include:Host 4 and road
By device 5;Host 4 is connect with the wireless communication unit in wearable device 1, the physiology for wireless communication unit transmission
Data;Wherein, application management software is provided in host 4, host 4 is led to above-mentioned physiological data by the application management software
It crosses wired or wireless connection and is transmitted to router 5;Router 5, the life for the application management software transmission in receiving host 4
After managing data, physiological data is communicated by socket by typing remote monitoring server 2.Data monitoring unit shown in Fig. 3 120
It is two, can is arbitrary in practical application, the present invention does not limit.
Host in this preferred embodiment can be that PC, PAD mobile phone step on terminal, the wireless communication list in wearable device 1
Member is preferably that bluetooth first passes after the data monitoring unit 120 in wearable device 1 detects user's breast physiological data
Microprocessor 130 is transported to, and then physiological data is transmitted to by host 4, then couple in router 5 by bluetooth by microprocessor 130,
Router 5 accesses in internet, and physiological data is then passed remote monitoring server 2.
Optionally, application software is provided in remote equipment 3, remote equipment 3 is additionally operable to pass through using the application software
The physiological data of 2 typing of socket communications access remote monitoring server, and be managed.In addition, remote equipment 3 can also be used
In, to wearable device 1 send control instruction, by wearable device 1 according to the control instruction detection, stop detection and/
Or suspend mode.
Based on Breast health remote supervision system shown in Fig. 3, the data flow that wearable device 1 detects can be as follows:
1, the microprocessor 130 in wearable device 1 is transferred data to by bluetooth on host 4, has one on host 4
Physiological data can be transmitted on router 5 by a application management software;
2, router 5 is communicated by socket by typing remote monitoring server 2, and remote monitoring server 2 records micro- place
The physiological data that reason device 130 sends over;
3, the software that remote equipment 3 (can be PC machine, can be mobile phone) operates above, it is remote by socket communications access
Journey monitoring server 2 recalls to the physiological data of typing, and is managed and (deletes, draw, the operations such as retrieval);
4, remote equipment 3 can also send control instruction remote control wearable device 1 and be stopped, starts to work, stop
Dormancy or refresh data.
In the preferred embodiment, BLE low-power consumption bluetooths can be used from microprocessor 130 to the near-end communication of host 4
Chipset, the bluetooth in wearable device 1 are main equipment (for searching for bluetooth, actively matching), the bluetooth at 4 end of host be from
Equipment.Also, host 4 needs the function of being provided simultaneously with WiFi and Bluetooth communication, such as general smart mobile phone all have WiFi and
The function of bluetooth, host be PC machine when some PC machine there is no WiFi or Bluetooth function, can use usb expansion WiFi module or
Person's usb expansion bluetooth module is completed.Router 5 preferentially selects wireless router, and accesses internet, there is public network IP address, protects
It is unobstructed to hold network.Remote monitoring server 2 is long-range general server (server of such as webpage), there is data management, forwarding number
According to, forward the function of instruction processing task, allow access multiple client.Remote equipment 3 can be PC machine, mobile phone, PAD, on
There is application software in face, and application software opens socket communication functions, and carries out the good interface of user, has drawing 3D map analysis
Function.And alarm can be synchronized in the generation of any one communication node or all nodes for the warning message of generation, this
Invention does not limit.
Optionally, remote monitoring server 2 can also be that each user establishes individual individual database, each user
A wearable device user is represented, carrying out classification to the physiological data of same user, evaluation process and judging result deposits
Storage, and then facilitate the data mining in later stage, provide more accurately monitoring conclusion to the user.Remote monitoring server 2 is connected
Wearable device 1, remote equipment 3 quantity, related to number of users, the present invention does not limit.
Mentioned above, remote equipment 3 can call the physiological data that remote monitoring server 2 stores, and to physiological data into
Row administrative analysis, to obtain the Breast health situation of user.Optionally, remote equipment 3 can be used for calling long-range monitoring service
It is inputted after 2 storage temperature data of device and presets grader, presetting grader by this identifies that above-mentioned temperature data is normal temperature data
And/or abnormal temperature data, and export recognition result;Wherein, grader is preset to suffer from based on healthy breast temperature data, determination
The breast temperature data of mammary gland disease and the doubtful breast temperature training with mammary gland disease obtain.
Grader is a kind of algorithm, and the description and feature which can be based on the object of input distribute class label.Point
The input of class device can be one or more data, and the output of the characteristic based on input and the highest label of input matching degree.
Before the use, it needs to build sorter model first with training dataset, when being trained to sorter model, instruction can be based on
Practice extraction partial data input model in data set and be iterated training, and then corrects training result.Training in the present embodiment
Data set can be the acquisition of the data to having case, such as healthy breast temperature data, the determining breast with mammary gland disease
Room temperature data and the doubtful breast temperature with mammary gland disease.
By taking breast cancer as an example, healthy breast temperature data may be used and the breast for being diagnosed as breast cancer in training dataset
Temperature data can also be specific and not make a definite diagnosis but the breast temperature data of doubtful breast cancer.The output result of grader then can be with
It is set according to demand, for example, it can be set to the temperature data inputted is carcinous and non-cancerous.
In a preferred embodiment of the invention, classifier system can pass through recurrent neural network (Recurrent Neural
Network, RNN), the realizations such as group of radial basis function, gauss hybrid models, FUZZY NETWORK and support vector machines.When training then
Network training is carried out using backpropagation or neural evolution.
In another preferred embodiment of the present invention, remote equipment 3 is additionally operable to call 2 designated time period of remote monitoring server
The temperature data of interior at least one temperature monitoring unit transmission, calculates being averaged for each temperature monitoring unit in the designated time period
Temperature value;The coordinate data of each temperature monitoring unit relative usage person's breast is obtained, based on coordinate data and corresponding average
Temperature value is drawn the temperature pattern of user's breast and is shown;Wherein, institute's coordinate data includes:With the water of user's nipple
The distance of gentle vertical direction.When being shown, can be displayed in full screen in the display interface of remote equipment 3, or with it is strong
Health temperature pattern is shown to comparison, or uses more lively display mode, and the physiological data of user is such as mapped human mould
The first-class mode of type, the present invention do not limit.
Due to daytime, night, the objective factors such as front and back, weather of user's movement can cause the temperature of user's breast
Influence, therefore, in order to ensure wearable device measure breast temperature data accuracy and reliability, carry out data analysis
When, the temperature data that can be extracted in designated time period is analyzed, such as user's sleep, under the non-athletic state, with
And the ambient temperature equal periods, and then promotion precision of analysis in the normal temperature range.
Fig. 4 shows the breast temperature 3D four-dimensional images with breast cancer of the preferred embodiment of the present invention, wherein central point
For user's nipple, X, Y respectively represent the distance apart from the horizontal and vertical direction of user's nipple, unit cm, Z-direction generation
Table temperature value, fourth dimension color data then show as Temperature Distribution.Based on the figure it is found that having a position temperature compared with it in user
His position temperature drift, then judges that the user may have breast cancer risk at this time.
User is reminded when judging that user there may be mammary gland disease risk, therefore, remote equipment 3,
It is additionally operable to:When judging that the breast of user sends abnormal based on above-mentioned physiological data, send alarm signal, such as auditory tone cues or
The text prompt etc. of information pop-up.
The judging result that remote equipment 3 sends out remote monitoring server 2 can be by the application in distally mounted equipment 3
Program is shown that the remote equipment 2 can be mobile phone, tablet computer, the laptop etc. that user usually uses, the present invention
It does not limit.
Optionally, remote equipment 3 can also be drawn data variation curve is simultaneously analyzed, preferably can be by with data class
Type and time build coordinate system respectively as ordinate, abscissa, and according to measured physiology in constructed coordinate system
Data draw coordinate points to obtain change curve, when concrete analysis, up and down that can be to data change curve or steady trend
Judged.As an example it is assumed that breast temperature curve is in rising trend, and is higher than normal temperature range, then user is judged
Breast is likely to occur exception, then diagnoses user's breast at this time and may have and suffers from risk of mammary gland disease etc..
In addition, breast normal temperature data and correspondingly standard temperature curve can be prestored in remote equipment 3, and
The breast temperature data of user is compared with normal temperature data, assessing wearable device according to the otherness of the two makes
Whether user's breast has mammary gland disease risk.Can be accurately judged to wearable device by the comparison with normal data makes
User is compared to the embodiment for occurring exception for normal temperature data, such as often relatively low, humidity is relatively normally higher etc. for temperature correction,
And then the clinical manifestation of comprehensive analysis user, provide data reference for diagnosis of breast diseases type.
Based on same inventive concept, the embodiment of the present invention additionally provides a kind of Breast health remote monitoring method, is applied to
The Breast health being made of wearable device, remote monitoring server and remote equipment in above-described embodiment, which remotely monitors, is
System, as shown in figure 5, the above method may include:
Step S501, the physiological data of control wearable device detection wearable device user's breast;
Step S502, the physiological data of typing wearable device transmission are simultaneously stored, and remote monitoring server is called to deposit
The part physiological data of storage, and analysis is managed to physiological data, to obtain the Breast health situation of user.Based on above-mentioned
Monitoring method mainly by the physiological data situation of change of wearable device actively monitoring user's breast, with when sending abnormal and
When issue the user with warning, remind user to see a doctor as early as possible.For women, the case where its own is not recognized
Under, help it to carry out early detection to udder health situation, to protect female breast healthy.
An embodiment of the present invention provides a kind of Breast health remote supervision system and methods, can by wearable device detection
Be uploaded to remote monitoring server after the physiological data of wearable device user's breast, by remote monitoring server carry out typing with
It is called at any time for remote equipment, and then analysis is managed to the breast physiological data of user, the mammary gland for obtaining user is strong
Health situation.In embodiments of the present invention, the physiological data of user's breast is carried out by using convenient wearable device hidden
Shape detects, and can obtain the active detecting breast in the case where user itself can not discover meeting the while of dressing primary demand
Room physiological data can issue the user with warning when judging that user may have Breast health hidden danger in time, and effectively auxiliary makes
User pinpoints the problems as early as possible, with timely medical check.
In the instructions provided here, numerous specific details are set forth.It is to be appreciated, however, that the implementation of the present invention
Example can be put into practice without these specific details.In some instances, well known method, structure is not been shown in detail
And technology, so as not to obscure the understanding of this description.
Similarly, it should be understood that in order to simplify the disclosure and help to understand one or more of each inventive aspect,
Above in the description of exemplary embodiment of the present invention, each feature of the invention is grouped together into single implementation sometimes
In example, figure or descriptions thereof.However, the method for the disclosure should be construed to reflect following intention:It is i.e. required to protect
Shield the present invention claims the more features of feature than being expressly recited in each claim.More precisely, as following
Claims reflect as, inventive aspect is all features less than single embodiment disclosed above.Therefore,
Thus the claims for following specific implementation mode are expressly incorporated in the specific implementation mode, wherein each claim itself
All as a separate embodiment of the present invention.
Those skilled in the art, which are appreciated that, to carry out adaptively the module in the equipment in embodiment
Change and they are arranged in the one or more equipment different from the embodiment.It can be the module or list in embodiment
Member or component be combined into a module or unit or component, and can be divided into addition multiple submodule or subelement or
Sub-component.Other than such feature and/or at least some of process or unit exclude each other, it may be used any
Combination is disclosed to all features disclosed in this specification (including adjoint claim, abstract and attached drawing) and so to appoint
Where all processes or unit of method or equipment are combined.Unless expressly stated otherwise, this specification (including adjoint power
Profit requires, abstract and attached drawing) disclosed in each feature can be by providing the alternative features of identical, equivalent or similar purpose come generation
It replaces.
In addition, it will be appreciated by those of skill in the art that although some embodiments described herein include other embodiments
In included certain features rather than other feature, but the combination of the feature of different embodiments means in of the invention
Within the scope of and form different embodiments.For example, in detail in the claims, embodiment claimed it is one of arbitrary
It mode can use in any combination.
It should be noted that the present invention will be described rather than limits the invention for above-described embodiment, and ability
Field technique personnel can design alternative embodiment without departing from the scope of the appended claims.In the claims,
Any reference mark between bracket should not be configured to limitations on claims.Word "comprising" does not exclude the presence of not
Element or step listed in the claims.Word "a" or "an" before element does not exclude the presence of multiple such
Element.The present invention can be by means of including the hardware of several different elements and being come by means of properly programmed computer real
It is existing.In the unit claims listing several devices, several in these devices can be by the same hardware branch
To embody.The use of word first, second, and third does not indicate that any sequence.These words can be explained and be run after fame
Claim.
So far, although those skilled in the art will appreciate that present invention has been shown and described in detail herein multiple shows
Example property embodiment still without departing from the spirit and scope of the present invention, still can according to the present disclosure directly
Determine or derive many other variations or modifications consistent with the principles of the invention.Therefore, the scope of the present invention is understood that and recognizes
It is set to and covers other all these variations or modifications.
Claims (13)
1. a kind of Breast health remote supervision system, including:Wearable device, remote monitoring server and remote equipment;Its
In,
The wearable device, the physiological data for detecting wearable device user's breast, and will be on the physiological data
Reach the remote monitoring server;
The remote monitoring server is communicated to connect with the wearable device, for receiving wearable device described in simultaneously typing
The physiological data of upload;
Remote equipment is communicated to connect with the remote monitoring server, the life for calling the remote monitoring server storage
Data are managed, and analysis is managed to the physiological data, to obtain the Breast health situation of the user.
2. system according to claim 1, wherein the wearable device includes:
With the chest support of wearable device user's breast contact setting, including left chest support and/or right chest support;
It is set at least one of the left chest support and/or the right chest support temperature monitoring unit and the temperature monitoring list
The microprocessor of metadata connection;Wherein,
The data monitoring cell distribution is in the left chest support and/or right chest support, for detecting the left and right breast of the user
Temperature data;
The microprocessor, the temperature data for receiving the temperature monitoring unit transmission are recorded.
3. system according to claim 2, wherein the wearable device further includes:Wireless communication unit, and it is described micro-
Processor data direct or indirect connection is communicated to connect for being established with the remote monitoring server, by the microprocessor
The physiological data of device record is transmitted to the remote monitoring server.
4. system according to claim 3, wherein further include:Host and router;
The host is connect with the wireless communication unit in the wearable device, is passed for receiving the wireless communication unit
Defeated physiological data;
Wherein, it is provided with application management software in the host, the host is by the application management software by the physiology
Data are transmitted to the router by wired or wireless connection;
The router, after the physiological data of application management software transmission in receiving the host, by the physiology
Remote monitoring server described in data inputting.
5. system according to claim 4, wherein be provided with application software, the remote equipment in the remote equipment
It is additionally operable to the physiological data using remote monitoring server typing described in the application software communications access, and is managed point
Analysis.
6. according to claim 1-5 any one of them systems, wherein the remote equipment is additionally operable to, and wearable is set to described
Preparation send control instruction, by the wearable device according to the control instruction detection, stop detection and/or suspend mode.
7. system according to claim 2, wherein the temperature monitoring unit is set in flexible substrate, based on described
The breast contact of flexible substrate and the user;
The temperature monitoring unit includes:Infrared temperature monitoring unit, temperature sensing monitoring unit and/or Non-ionizing radiation monitoring
Unit.
8. system according to claim 7, wherein the wearable device is further used for:
The quantity of the temperature monitoring unit is customized according to the breast temperature related parametric of the user;And in the temperature
When degree monitoring unit is multiple, multiple temperature monitoring cell-averages are distributed in flexible substrate, the flexible liner is passed through
Bottom is set in the left chest support and/or the right chest support and with described with wearable device user's breast contact.
9. system according to claim 8, wherein the remote monitoring server is additionally operable to:
Individual database is created for the user, the temperature data that the wearable device transmits is stored to a number
According to library.
10. system according to claim 9, wherein the remote equipment is additionally operable to:
Default grader is inputted after calling the remote monitoring server storage temperature data, institute is identified by the default grader
It is normal temperature data and/or abnormal temperature data to state temperature data, and exports recognition result;
Wherein, the default grader based on healthy breast temperature data, determine with mammary gland disease breast temperature data with
And the doubtful breast temperature training with mammary gland disease obtains.
11. system according to claim 10, wherein the remote equipment is additionally operable to:
The temperature data for calling at least one temperature monitoring unit transmission in the remote monitoring server designated time period, calculates
The average temperature value of each temperature monitoring unit in the designated time period;
The coordinate data of the relatively described user's breast of each temperature monitoring unit is obtained, based on the coordinate data and right
The average temperature value answered draws the temperature pattern of user's breast;Wherein, the coordinate data includes:With the user
The distance in the horizontal and vertical direction of nipple.
12. according to claim 1-5 any one of them systems, wherein the remote equipment is additionally operable to:When based on the life
When reason data judge that the breast of the user sends abnormal, alarm signal is sent.
13. a kind of Breast health remote monitoring method is applied to by wearable device, remote monitoring server and remote equipment
The Breast health remote supervision system of composition, the method includes:
Control wearable device detects the physiological data of the wearable device user breast;
The physiological data of wearable device transmission described in typing is simultaneously stored, and the portion of the remote monitoring server storage is called
Divide physiological data, and analysis is managed to the physiological data, to obtain the Breast health situation of the user.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201810915953.9A CN108720814A (en) | 2018-08-13 | 2018-08-13 | A kind of Breast health remote supervision system and method |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201810915953.9A CN108720814A (en) | 2018-08-13 | 2018-08-13 | A kind of Breast health remote supervision system and method |
Publications (1)
Publication Number | Publication Date |
---|---|
CN108720814A true CN108720814A (en) | 2018-11-02 |
Family
ID=63942879
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201810915953.9A Pending CN108720814A (en) | 2018-08-13 | 2018-08-13 | A kind of Breast health remote supervision system and method |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN108720814A (en) |
Cited By (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN109431474A (en) * | 2018-11-29 | 2019-03-08 | 深圳市衣信互联网科技有限公司 | A kind of monitoring mammary gland early warning system and its monitoring method based on NB-IOT |
CN109620147A (en) * | 2018-11-29 | 2019-04-16 | 深圳市衣信互联网科技有限公司 | A kind of monitoring mammary gland early warning system and its monitoring method based on NFC |
CN109907730A (en) * | 2019-01-16 | 2019-06-21 | 平安医疗健康管理股份有限公司 | A kind of data processing method, device and storage medium and computer equipment |
CN112971732A (en) * | 2021-01-14 | 2021-06-18 | 管晓翔 | Intelligent underwear capable of early warning breast tumors |
CN114468996A (en) * | 2021-12-20 | 2022-05-13 | 香港生物节律研究院有限公司 | Method for analyzing breast signs based on orderliness, multimodality and symmetry deficiency |
CN115588509A (en) * | 2022-10-19 | 2023-01-10 | 秦皇岛市惠斯安普医学系统股份有限公司 | Multi-mode mammary gland health detection system |
Citations (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20050020921A1 (en) * | 2003-07-10 | 2005-01-27 | Tpg Applied Technology | Ultrasonic sensor garment for breast tumor |
CN103514357A (en) * | 2012-12-31 | 2014-01-15 | Tcl集团股份有限公司 | Remote health supervising method and supervising system thereof |
CN105146783A (en) * | 2015-10-13 | 2015-12-16 | 翁小翠 | Intelligent bra |
CN105662361A (en) * | 2015-12-18 | 2016-06-15 | 上海温尔信息科技有限公司 | Continuous body temperature monitoring instrument |
CN106617343A (en) * | 2016-12-30 | 2017-05-10 | 安徽尤泰克医疗科技有限公司 | Health care bra |
CN106859680A (en) * | 2017-03-06 | 2017-06-20 | 桐乡匹昂电子科技有限公司 | A kind of breast examination control system |
CN106913320A (en) * | 2017-03-16 | 2017-07-04 | 中科(深圳)精准医疗技术有限公司 | A kind of artificial intelligence brassiere |
CN107440692A (en) * | 2017-07-28 | 2017-12-08 | 刘国强 | Breast cancer provisional monitor brassiere based on the monitoring of temperature spectra microwave integrated |
CN108056760A (en) * | 2018-01-17 | 2018-05-22 | 深圳市衣信互联网科技有限公司 | Breast cancer detection underwear and detecting system |
-
2018
- 2018-08-13 CN CN201810915953.9A patent/CN108720814A/en active Pending
Patent Citations (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20050020921A1 (en) * | 2003-07-10 | 2005-01-27 | Tpg Applied Technology | Ultrasonic sensor garment for breast tumor |
CN103514357A (en) * | 2012-12-31 | 2014-01-15 | Tcl集团股份有限公司 | Remote health supervising method and supervising system thereof |
CN105146783A (en) * | 2015-10-13 | 2015-12-16 | 翁小翠 | Intelligent bra |
CN105662361A (en) * | 2015-12-18 | 2016-06-15 | 上海温尔信息科技有限公司 | Continuous body temperature monitoring instrument |
CN106617343A (en) * | 2016-12-30 | 2017-05-10 | 安徽尤泰克医疗科技有限公司 | Health care bra |
CN106859680A (en) * | 2017-03-06 | 2017-06-20 | 桐乡匹昂电子科技有限公司 | A kind of breast examination control system |
CN106913320A (en) * | 2017-03-16 | 2017-07-04 | 中科(深圳)精准医疗技术有限公司 | A kind of artificial intelligence brassiere |
CN107440692A (en) * | 2017-07-28 | 2017-12-08 | 刘国强 | Breast cancer provisional monitor brassiere based on the monitoring of temperature spectra microwave integrated |
CN108056760A (en) * | 2018-01-17 | 2018-05-22 | 深圳市衣信互联网科技有限公司 | Breast cancer detection underwear and detecting system |
Cited By (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN109431474A (en) * | 2018-11-29 | 2019-03-08 | 深圳市衣信互联网科技有限公司 | A kind of monitoring mammary gland early warning system and its monitoring method based on NB-IOT |
CN109620147A (en) * | 2018-11-29 | 2019-04-16 | 深圳市衣信互联网科技有限公司 | A kind of monitoring mammary gland early warning system and its monitoring method based on NFC |
CN109907730A (en) * | 2019-01-16 | 2019-06-21 | 平安医疗健康管理股份有限公司 | A kind of data processing method, device and storage medium and computer equipment |
CN112971732A (en) * | 2021-01-14 | 2021-06-18 | 管晓翔 | Intelligent underwear capable of early warning breast tumors |
CN114468996A (en) * | 2021-12-20 | 2022-05-13 | 香港生物节律研究院有限公司 | Method for analyzing breast signs based on orderliness, multimodality and symmetry deficiency |
WO2023119103A1 (en) * | 2021-12-20 | 2023-06-29 | 香港生物节律研究院有限公司 | Method for analyzing breast signs on basis of orderliness, multiple modalities and symmetry breaking |
CN114468996B (en) * | 2021-12-20 | 2024-01-23 | 香港生物节律研究院有限公司 | Method for analyzing breast signs based on order, multi-mode and symmetry deficiency |
CN115588509A (en) * | 2022-10-19 | 2023-01-10 | 秦皇岛市惠斯安普医学系统股份有限公司 | Multi-mode mammary gland health detection system |
CN115588509B (en) * | 2022-10-19 | 2023-05-02 | 秦皇岛市惠斯安普医学系统股份有限公司 | Multi-mode breast health detection system |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CN108720814A (en) | A kind of Breast health remote supervision system and method | |
CN101856227B (en) | Breast electrical impedance fault imager based on mobile phone platform | |
US11672427B2 (en) | Systems and methods for tissue assessment | |
US20160296135A1 (en) | Electrical impedance tomography device | |
Madhvapathy et al. | Reliable, low-cost, fully integrated hydration sensors for monitoring and diagnosis of inflammatory skin diseases in any environment | |
WO2019000073A1 (en) | Method for sensing of biometric data and use thereof for determining emotional state of a user | |
CN108056760A (en) | Breast cancer detection underwear and detecting system | |
CN104223385A (en) | Intelligent bra for early detection of breast cancer | |
CN104523244B (en) | Wearable-type electronic device and control method based on human body metabolism | |
CN107440692A (en) | Breast cancer provisional monitor brassiere based on the monitoring of temperature spectra microwave integrated | |
CN107373791B (en) | Intelligent bra, chest temperature monitoring system and analysis method | |
CN108703746A (en) | A kind of wearable device for detecting breast disease | |
CN105455810A (en) | Bioelectricity-impedance-based wearable leg ring capable of measuring body compositions | |
CN108720813A (en) | A kind of flexible sensor for breast cancer monitoring | |
CN109008986A (en) | A kind of chest detection method, electronic equipment and health monitor | |
CN108720812A (en) | A kind of Breast health apparatus for evaluating using mammary gland external temperature data | |
JP2020533112A (en) | Wireless active monitoring implant system | |
CN108042106A (en) | A kind of artificial intelligence method for correcting error for improving human body physical sign Non-invasive detection equipment accuracy of detection | |
CN205322327U (en) | Wearable foot ring based on human composition of bio -electrical impedance measurable quantity | |
CN105520721A (en) | Cancerization region precise measuring and recognizing device based on body surface temperature field | |
CN211324977U (en) | Mammary gland health remote monitoring system | |
US20220095996A1 (en) | Wearable medical device | |
CN108209881B (en) | A kind of foot status early warning method and device | |
GB2444145A (en) | Body temperature detection clothing piezoelectrically powered from body motion | |
CN106214149A (en) | The breast carcinoma system of Risk Monitoring assessment in early days |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PB01 | Publication | ||
PB01 | Publication | ||
SE01 | Entry into force of request for substantive examination | ||
SE01 | Entry into force of request for substantive examination |