CN108392173A - Multispectral fundus imaging equipment - Google Patents
Multispectral fundus imaging equipment Download PDFInfo
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- CN108392173A CN108392173A CN201810186147.2A CN201810186147A CN108392173A CN 108392173 A CN108392173 A CN 108392173A CN 201810186147 A CN201810186147 A CN 201810186147A CN 108392173 A CN108392173 A CN 108392173A
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- illuminating lens
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- light source
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B3/00—Apparatus for testing the eyes; Instruments for examining the eyes
- A61B3/10—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions
- A61B3/12—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions for looking at the eye fundus, e.g. ophthalmoscopes
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B3/00—Apparatus for testing the eyes; Instruments for examining the eyes
- A61B3/0008—Apparatus for testing the eyes; Instruments for examining the eyes provided with illuminating means
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B3/00—Apparatus for testing the eyes; Instruments for examining the eyes
- A61B3/0016—Operational features thereof
- A61B3/0041—Operational features thereof characterised by display arrangements
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B3/00—Apparatus for testing the eyes; Instruments for examining the eyes
- A61B3/10—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions
- A61B3/14—Arrangements specially adapted for eye photography
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- Health & Medical Sciences (AREA)
- Medical Informatics (AREA)
- Biophysics (AREA)
- Ophthalmology & Optometry (AREA)
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- Heart & Thoracic Surgery (AREA)
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- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
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- Eye Examination Apparatus (AREA)
Abstract
The collimated mirror of diverging light of multispectral fundus imaging equipment provided by the invention, light source outgoing forms collimated light beam；Line beam is formed after parallel beam incident to cylindrical lens focus, Line beam is incident after spectroscope transmits to enter scanning galvanometer, the reflection angle that scanning galvanometer changes incident Line beam forms scanning light beam, after scanning light beam focuses on pupil after the first illuminating lens, the second illuminating lens successively and reaches eyeground；Through the imaging beam of fundus reflex, incidence enters spectroscope after the second illuminating lens, the first illuminating lens, scanning galvanometer successively again, incident imaging beam is reflexed to imaging len with spectroscope and imaged lens focus is at dispersion element, imaging beam is separated into different angles after the dispersion element and is detected through probe unit, and probe unit converts the optical signal of detection to electric signal；Circuit control module obtains the electric signal and converts the electric signal to picture signal and export to display module and shows, compact-sized, easy to operate.
Description
Technical field
The present invention relates to a kind of multi-optical spectrum imaging technology belonged in Application Optics more particularly to a kind of multispectral eyeground at
As equipment.
Background technology
In recent years, it since total focusing technology can use slit or aperture to filter out the stray light of non-imaged plane, carries significantly
High imaging resolution, and be copolymerized coke and have the advantages that non-intrusive inspection, increasingly become the hot spot that ophthalmology is imaged.Tradition
Spot scan copolymerization coke be using two sides galvanometer simultaneously scan so that light source illuminates the every bit of object to be measured, pass through its reflect
Light or fluorescence imaging, when object under test size is bigger, the time that piece image completes scanning needs is longer, is swept to galvanometer
Retouching rate request also becomes higher.And the line scanning confocal imaging developed on this basis replaces point using one-dimensional scanning Line beam
Beam lighting, this method resolution ratio is less than point confocal imaging, but system is simpler, and detectivity is high, imaging frame
Frequency is high, and advantage is had more compared to front method.
Fundus imaging is a widely applied checkup item in ophthalmology, and optical fundus blood vessel is that human body uniquely can be straight by body surface
Connect the blood vessel observed.By the observation to eye fundus image, doctor can both diagnose eyeground pathological changes, can also be to other
Systemic disease carries out state of an illness judgement, such as cerebral infarction, cerebral hemorrhage, cerebral arteriovenous malformation, brain tumor, diabetes, nephrosis, hypertension.
But traditional funduscopy instrument is generally desk-top, contains complicated lighting system and observing system, bulky, system
It is complicated；Some instruments need the software of characteristic on computers that can just use, and machine itself does not have image storage
Function, or even computer autonomous working can not be detached from.If necessary to eye fundus image, then eyeground figure is shot before needing patient to instrument
Piece, it is all highly inconvenient to the bed patient of especial patient, especially hospital, or to the patient of Marginal Mountainous Areas.Meanwhile unicast
Long fundus imaging technology cannot meet the needs of ophthalmic diagnosis, and therefore, therefore a kind of multispectral fundus imaging of urgent need is set
It is standby.
Invention content
Have in view of that, it is necessary to which a kind of multispectral fundus imaging equipment is provided, it is intended to which the eye provided in the prior art is provided
Bottom imaging device structure is complicated and cannot be satisfied ophthalmic diagnosis needs.
To achieve the above object, the present invention uses following technical proposals:
On the one hand, multispectral fundus imaging equipment provided by the invention, including optical imaging assemblies, circuit control module and
The display module being electrically connected with the circuit control module；
The optical imaging assemblies include light source module, lighting module and image-forming module；The light source module includes light source
And collimating mirror；The lighting module includes cylindrical lens, spectroscope, scanning galvanometer and illuminating lens group, the illuminating lens group
Including the first illuminating lens and the second illuminating lens, second illuminating lens can be moved back and forth along center axis；It is described at
As module includes imaging len, dispersion element and probe unit；
The circuit control module is electrically connected the scanning galvanometer and the probe unit, and the circuit control module is used
In the velocity of rotation and rotational angle that control the scanning galvanometer；
The diverging light of the light source outgoing forms collimated light beam through the collimating mirror；The parallel beam incident is to the column
Line beam is formed after the lens focus of face, the Line beam is incident into the scanning galvanometer after spectroscope transmission, described
The reflection angle that scanning galvanometer changes the incident Line beam forms scanning light beam, and the scanning light beam is successively through described first
It is focused on after pupil after illuminating lens, the second illuminating lens and reaches eyeground；
Imaging beam through fundus reflex again successively through second illuminating lens, first illuminating lens, described sweep
Incidence enters the spectroscope after retouching galvanometer, and incident imaging beam is reflexed to the imaging len and through institute by the spectroscope
It states imaging len to focus at the dispersion element, the imaging beam is separated into different angles simultaneously after the dispersion element
It is detected through the probe unit, the probe unit converts the optical signal of detection to electric signal；
The circuit control module obtains the electric signal and converts the electric signal to picture signal and exports to described
Display module is shown.
In some preferred embodiment, the light source includes broadband white light source or the light that is sent out by multiple single wavelength light sources
Coupled obtained mixing light source, the broadband white light source include white light emitting diode, white light superluminescent diode, superradiance
Laser or halogen lamp.
In some preferred embodiment, the illuminating lens group further includes guide rail, the extending direction of the guide rail with it is described
First illuminating lens, the central axial direction of the second illuminating lens are consistent, and first illuminating lens and the second illuminating lens can
It is slidably arranged on the guide rail.
In some preferred embodiment, first illuminating lens is lens, and second illuminating lens is preset lens.
In some preferred embodiment, the dispersion element is the broadband diffraction light coral of 300lp/mm, the probe unit
For area array CCD.
In some preferred embodiment, the display module includes LED display, LCD display or AMOLED display screens.
In some preferred embodiment, further include the shell of the fixed display module.
In some preferred embodiment, adjustment module is further fixed on the shell, the adjustment module is for adjusting institute
State position of the illuminating lens group with respect to human eye.
In some preferred embodiment, the adjustment module includes adjustment gear and adjusting screw rod, described in adjusting
Adjustment gear and the adjusting screw rod move to control first illuminating lens and the second illuminating lens along the sliding rail.
In some preferred embodiment, interface module is further fixed on the shell, the interface module includes that light source connects
Mouth and data-interface, the optical-path interface are used to that light source to be accessed light path by described, and the data-interface is used for described image
Signal transmission shows or stores to the display module, and the interface module is for adjusting the illuminating lens group with respect to human eye
Position.
The present invention uses above-mentioned technical proposal, can realize following advantageous effects：
Multispectral fundus imaging equipment provided by the invention, including optical imaging assemblies, circuit control module and display mould
Block, the optical imaging assemblies include light source module, lighting module and image-forming module；The light source module includes light source and collimation
Mirror；The lighting module includes cylindrical lens, spectroscope, scanning galvanometer and illuminating lens group, and the illuminating lens group includes the
One illuminating lens and the second illuminating lens, the image-forming module include imaging len, dispersion element and probe unit；The light source
The diverging light of outgoing forms collimated light beam through the collimating mirror；It is formed after the parallel beam incident to the cylindrical lens focus
Line beam, the Line beam is incident after spectroscope transmission to enter the scanning galvanometer, and the scanning galvanometer changes incident
The Line beam reflection angle formed scanning light beam, the scanning light beam successively through first illuminating lens, second shine
It is focused on after bright lens after pupil and reaches eyeground；Imaging beam through fundus reflex again successively through second illuminating lens,
Incident after first illuminating lens, the scanning galvanometer to enter the spectroscope, the spectroscope is by incident imaging beam
It reflexes to the imaging len and is focused at the dispersion element through the imaging len, the imaging beam is through the dispersion
It is separated into different angles after unit and is detected through the probe unit, the probe unit converts the optical signal of detection to electricity
Signal；The circuit control module obtains the electric signal and converts the electric signal to picture signal and exports to the display
Module shows that multispectral fundus imaging equipment provided by the invention is compact-sized, easy to operate, easy to carry；Meanwhile it adopting
It is imaged with multi-wavelength, it is Polaroid to meet a variety of inspection needs；And co-focusing imaging method, imaging resolution are scanned using line
Height, image taking speed are fast.
In addition, multispectral fundus imaging equipment provided by the invention, diopter is adjustable, to meet different eyesight crowds
The needs of fundus imaging；The image of acquisition not only can display real-time, but also can be connect with host computer, realize image transmission, display with
Storage.
Description of the drawings
Fig. 1 is the structural schematic diagram of multispectral fundus imaging equipment provided in this embodiment.
Fig. 2 a are the horizontal direction light path schematic diagram of multispectral fundus imaging equipment provided in this embodiment.
Fig. 2 b are the light path schematic diagram of the vertical direction of multispectral fundus imaging equipment provided in this embodiment.
Fig. 3 provides the control schematic diagram of the circuit control module of multispectral fundus imaging equipment for the embodiment of the present invention.
Specific implementation mode
In order to make the purpose , technical scheme and advantage of the present invention be clearer, with reference to the accompanying drawings and embodiments, right
The present invention is further elaborated.It should be appreciated that the specific embodiments described herein are merely illustrative of the present invention, and
It is not used in the restriction present invention.
It please refers to Fig.1 and 2 (a), 2 (b), is multispectral fundus imaging equipment 10 provided in an embodiment of the present invention, including light
Learn image-forming assembly 110, circuit control module 120 and the display module 130 being electrically connected with the circuit control module 120.Its
In：
The optical imaging assemblies 110 include light source module 111, lighting module 112 and image-forming module 113.
The light source module 111 includes light source 1111 and collimating mirror 1112.
In some preferred embodiments, the light source 1111 includes broadband white light source or is sent out by multiple single wavelength light sources
The coupled obtained mixing light source of light gone out, the broadband white light source include white light emitting diode, white light superluminescent diode,
Super radiation laser or halogen lamp.
It is appreciated that the light beam that the light source 1111 is emitted is transformed to collimated light beam after the collimating mirror 1112.
The lighting module 112 includes cylindrical lens 1121, spectroscope 1122, scanning galvanometer 1123 and illuminating lens group
1124。
In some preferred embodiments, the cylindrical lens 1121 is double glued cylindrical lenses.
In some preferred embodiments, the spectroscope 1122 is 10/90 to the transmission of light beam and reflectivity.
In some preferred embodiments, scan module 1123 is high-velocity scanning galvanometer.
It is appreciated that control 1123 velocity of rotation of scanning galvanometer and rotational angle by circuit control module 120, so as to
Enough variations for making incident light beam reflection angle degree.
The illuminating lens group 1124 includes the first illuminating lens a and the second illuminating lens b, the second illuminating lens b
It can be moved back and forth along center axis.
In some preferred embodiments, first illuminating lens is the lens of f=50mm, second illuminating lens
For VOLK78D preset lens.
In some preferred embodiments, the illuminating lens group 1124 further includes guide rail c, the extension side of the guide rail c
To, the first illuminating lens a and consistent with the central axial direction of the first illuminating lens a and the second illuminating lens b
Two illuminating lens b are slidably disposed on the guide rail c.
In some preferred embodiments, guide rail c is additionally provided with adjustment module, adjustment module include adjustment gear d and
Adjusting screw rod e, by adjusting the adjustment gear d and adjusting screw rod e, to control the first illuminating lens a and the
Two illuminating lens b are moved along the sliding rail c, to meet the needs of different eyesight crowd fundus imagings.
The image-forming module 113 includes imaging len 1131, dispersion element 1132 and probe unit 1133.
In some preferred embodiments, imaging len 1131 is doublet lens, and the dispersion compensation module 1132 is
The broadband diffraction light coral of 300lp/mm, the detecting module 1133 are area array CCD, and the detecting module is by collected optical signal
It is converted into electric signal.
Multispectral fundus imaging equipment provided by the invention, operation principle are as follows：
The diverging light that the light source 1111 is emitted forms collimated light beam through the collimating mirror 1112；The parallel beam incident
Line beam is formed after being focused to the cylindrical lens 1121, the Line beam is incident after the transmission of the spectroscope 1122 to enter institute
Scanning galvanometer 1123 is stated, the reflection angle that the scanning galvanometer 1123 changes the incident Line beam forms scanning light beam, institute
It states after scanning light beam focuses on pupil after the first illuminating lens a, the second illuminating lens b successively and reaches eyeground m；
Imaging beam through fundus reflex is again successively through the second illuminating lens b, the first illuminating lens a, described
Incident after scanning galvanometer 1123 to enter the spectroscope 1122, the spectroscope 1122 reflexes to incident imaging beam described
Imaging len 1131 is simultaneously burnt at the dispersion element 1132 through the imaging len poly- 1131, and the imaging beam is through the color
It is separated into different angles after throwaway member 1132 and is detected through the probe unit 1133, the probe unit 1133 is by detection
Optical signal is converted into electric signal；Fig. 2 (a) and Fig. 2 (b) is please referred to, light is focused before dispersion element 1132 in vertical direction, water
Square to for directional light, shape is into a line；After dispersion element 1132, the light of different wave length is separated, and reaches probe unit
1133 photosurface
The circuit control module 120 obtains the electric signal and converts the electric signal to picture signal and exports to institute
State the display of display module 130.
Referring to Fig. 3, providing the control of the circuit control module 120 of multispectral fundus imaging equipment for the embodiment of the present invention
Schematic diagram.
Circuit control module 120 is electrically connected at the scan module 1123, the rotation for controlling scan module 1123
Speed and rotational angle make Line beam carry out one-dimensional scanning to fundus imaging.
Circuit control module 120 is also electrically connected at the probe unit 1133, for receiving the probe unit 1133
The electric signal of collected optical signal conversion, and convert the electric signal to picture signal and shown in real time by display module 130
Show, or is transmitted to computer.
Circuit control module 120 can also control to adjust module, when the fogging image that display module 130 is shown, electricity
Road control module 120 controls to adjust module and carries out certain adjusting to the relative position for illuminating lens group 1124, meets different bend
The needs of luminosity fundus imaging.
Circuit control module 120 is also electrically connected at button, and user can set the equipment many kinds of parameters by button
It sets, such as the power of lighting source energy, video and picture mode, browsing pictures pattern, light illumination mode, time setting, date
Setting etc..
In some preferred embodiment, the display module 130 is shown including LED display, LCD display or AMOLED
Screen.
In some preferred embodiments, multispectral fundus imaging equipment 100 further includes the fixed display module 130
Shell (not shown).
In some preferred embodiment, interface module 150 is further fixed on the shell, the interface module 150 includes
Light source interface 151 and data-interface 152, the light source interface 151 are used to that light source 1111 to be accessed light path, the data by described
Interface 152 is used to described image signal transmission to the display module showing 130 or storage.
The multispectral fundus imaging equipment of the embodiment of the present invention is appreciated that, in practical applications, first by multispectral eyeground
Imaging device is close to human eye, and by optical imagery module to human eye fundus imaging, obtained image passes through circuit control module 120
It is shown in after processing on display module 130 or by data-interface 152 by image transmitting to Computer display, if image is inadequate
Clearly, image-forming module 113 and illuminating lens group 1124 can be adjusted with respect to human eye by the adjustment module in adjustment housings
Position so that eye fundus image can clearly display, and after obtaining the preferable eye fundus image of effect, will be schemed by control button 153
As preserving on computers.
Multispectral fundus imaging equipment provided by the invention, it is compact-sized, it is easy to operate, it is easy to carry；Meanwhile it using
Multi-wavelength is imaged, Polaroid to meet a variety of inspection needs；And co-focusing imaging method is scanned using line, imaging resolution is high,
Image taking speed is fast.
In addition, multispectral fundus imaging equipment provided by the invention, diopter is adjustable, to meet different eyesight crowds
The needs of fundus imaging；The image of acquisition not only can display real-time, but also can be connect with host computer, realize image transmission, display with
Storage.
The foregoing is merely illustrative of the preferred embodiments of the present invention, is not intended to limit the invention, all essences in the present invention
All any modification, equivalent and improvement etc., should all be included in the protection scope of the present invention made by within refreshing and principle.
Claims (9)
1. a kind of multispectral fundus imaging equipment, which is characterized in that including optical imaging assemblies, circuit control module and with it is described
The display module that circuit control module is electrically connected；
The optical imaging assemblies include light source module, lighting module and image-forming module；The light source module includes light source and standard
Straight mirror；The lighting module includes cylindrical lens, spectroscope, scanning galvanometer and illuminating lens group, and the illuminating lens group includes
First illuminating lens and the second illuminating lens, second illuminating lens can be moved back and forth along center axis；The imaging mould
Block includes imaging len, dispersion element and probe unit；
The circuit control module is electrically connected the scanning galvanometer and the probe unit, and the circuit control module is for controlling
Make the velocity of rotation and rotational angle of the scanning galvanometer；
The diverging light of the light source outgoing forms collimated light beam through the collimating mirror；The parallel beam incident is saturating to the cylinder
Mirror forms Line beam after focusing, the Line beam is incident after spectroscope transmission to enter the scanning galvanometer, the scanning
The reflection angle that galvanometer changes the incident Line beam forms scanning light beam, and the scanning light beam is illuminated through described first successively
It is focused on after pupil after lens, the second illuminating lens and reaches eyeground；
Imaging beam through fundus reflex shakes through second illuminating lens, first illuminating lens, the scanning successively again
It is incident after mirror to enter the spectroscope, the spectroscope by incident imaging beam reflex to the imaging len and through it is described at
At the dispersion element, the imaging beam is separated into different angles after the dispersion element and through institute picture lens focus
Probe unit detection is stated, the probe unit converts the optical signal of detection to electric signal；
The circuit control module obtains the electric signal and converts the electric signal to picture signal and exports to the display
Module is shown.
2. multispectral fundus imaging equipment according to claim 1, which is characterized in that the light source includes broadband white light source
Or the coupled obtained mixing light source of light sent out by multiple single wavelength light sources, the broadband white light source includes white-light emitting two
Pole pipe, white light superluminescent diode, super radiation laser or halogen lamp.
3. multispectral fundus imaging equipment according to claim 1, which is characterized in that the illuminating lens group further includes leading
Rail, the extending direction of the guide rail is consistent with first illuminating lens and the central axial direction of the second illuminating lens, described
First illuminating lens and the second illuminating lens are slidably disposed on the guide rail.
4. multispectral fundus imaging equipment according to claim 1, which is characterized in that the dispersion element is broadband diffraction
Light coral, the probe unit are face battle array photosensitive unit.
5. multispectral fundus imaging equipment according to claim 1, which is characterized in that the display module includes LED aobvious
Display screen, LCD display or AMOLED display screens.
6. multispectral fundus imaging equipment according to claim 1, which is characterized in that further include the fixed display module
Shell.
7. multispectral fundus imaging equipment according to claim 6, which is characterized in that be further fixed on adjusting on the shell
Module, the adjustment module is for adjusting position of the illuminating lens group with respect to human eye.
8. multispectral fundus imaging equipment according to claim 7, which is characterized in that the adjustment module includes adjusting tooth
Wheel and adjusting screw rod, by adjusting the adjustment gear and the adjusting screw rod, to control first illuminating lens and
Second illuminating lens is moved along the sliding rail.
9. multispectral fundus imaging equipment according to claim 1, which is characterized in that be further fixed on interface on the shell
Module, the interface module include light source interface and data-interface, and the optical-path interface is used to that light source to be accessed light path by described,
The data-interface is for showing or storing described image signal transmission to the display module.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810186147.2A CN108392173A (en) | 2018-03-07 | 2018-03-07 | Multispectral fundus imaging equipment |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810186147.2A CN108392173A (en) | 2018-03-07 | 2018-03-07 | Multispectral fundus imaging equipment |
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| CN108392173A true CN108392173A (en) | 2018-08-14 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN201810186147.2A Pending CN108392173A (en) | 2018-03-07 | 2018-03-07 | Multispectral fundus imaging equipment |
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| CN110025287A (en) * | 2019-04-02 | 2019-07-19 | 深圳盛达同泽科技有限公司 | The lighting device of multispectral fundus imaging and multispectral fundus imaging equipment |
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| CN111657853A (en) * | 2020-06-01 | 2020-09-15 | 中国科学院苏州生物医学工程技术研究所 | High-speed self-adaptive line scanning fundus imaging system and method |
| CN111920377A (en) * | 2020-09-17 | 2020-11-13 | 常熟理工学院 | High-speed functional fundus three-dimensional detection system based on near-infrared light |
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| CN111657853A (en) * | 2020-06-01 | 2020-09-15 | 中国科学院苏州生物医学工程技术研究所 | High-speed self-adaptive line scanning fundus imaging system and method |
| CN111657853B (en) * | 2020-06-01 | 2023-04-14 | 中国科学院苏州生物医学工程技术研究所 | High-speed self-adaptive line scanning fundus imaging system and method |
| CN111920377A (en) * | 2020-09-17 | 2020-11-13 | 常熟理工学院 | High-speed functional fundus three-dimensional detection system based on near-infrared light |
| CN111920377B (en) * | 2020-09-17 | 2021-01-19 | 常熟理工学院 | High-speed functional fundus three-dimensional detection system based on near-infrared light |
| WO2022057402A1 (en) * | 2020-09-17 | 2022-03-24 | 常熟理工学院 | High-speed functional fundus three-dimensional detection system based on near-infrared light |
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