CN108158607A - A kind of Contrast-enhanced ultrasonography reminding method, device and ultrasonic device - Google Patents
A kind of Contrast-enhanced ultrasonography reminding method, device and ultrasonic device Download PDFInfo
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- A61B8/44—Constructional features of the ultrasonic, sonic or infrasonic diagnostic device
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- A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
- A61B8/46—Ultrasonic, sonic or infrasonic diagnostic devices with special arrangements for interfacing with the operator or the patient
- A61B8/467—Ultrasonic, sonic or infrasonic diagnostic devices with special arrangements for interfacing with the operator or the patient characterised by special input means
- A61B8/469—Ultrasonic, sonic or infrasonic diagnostic devices with special arrangements for interfacing with the operator or the patient characterised by special input means for selection of a region of interest
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- A—HUMAN NECESSITIES
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- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
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Abstract
The invention discloses a kind of Contrast-enhanced ultrasonography reminding method, including：In Contrast-enhanced ultrasonography, the contrast agent developed image in contrast agent development flow process is obtained in real time；When the developed image meets preset calibrations point decision condition, then the prompt message of corresponding preset calibrations point is generated, and export the prompt message；This method is by setting preset calibrations point, and whether reach corresponding preset calibrations point in automatic decision contrast agent development flow process, and the automatic prompt doctor when reaching, therefore degree of concern of the doctor to contrast agent perfusion developing time in contrastographic picture can be reduced, so as to improve the efficiency that doctor checks diagnosis.The invention also discloses a kind of Contrast-enhanced ultrasonography suggestion device and ultrasonic devices, have above-mentioned advantageous effect.
Description
Technical field
The present invention relates to ultrasonic device technical field, more particularly to a kind of Contrast-enhanced ultrasonography reminding method, device and super
Acoustic equipment.
Background technology
Ultrasonic contrast (ultrasonic contrast) is also known as acoustic contrast (acoustic contrast), is to utilize to make
Shadow agent enhances rear scattered echoes, hence it is evident that improves the resolving power of Ultrasonic Diagnosis, the technology of sensibility and specificity.At present, it is ultrasonic
During radiography clinical examination, doctor is needed according to flowing developing time of the contrast agent in patient as the foundation to diagnose the illness.
When carrying out Contrast-enhanced ultrasonography, doctor needs to pay high attention to the contrast agent perfusion developing time in contrastographic picture, by making
The observation of shadow image determines flowing developing time and corresponding stage general used time of the contrast agent in patient, finally by sight
The time observed is as the foundation to diagnose the illness and makes diagnosis.The diagnosis process of the above method is dependent on doctor to contrastographic picture
The degree of concern of middle contrast agent perfusion developing time is not easy to doctor and fast and accurately makes diagnosis, is also unfavorable for doctor to doubting
The antidiastole of difficult miscellaneous disease.
Therefore, how to simplify the operation that doctor carries out ultrasonic contrast, be ability so as to improve the efficiency that doctor checks diagnosis
Field technique personnel's technical issues that need to address.
Invention content
The object of the present invention is to provide a kind of Contrast-enhanced ultrasonography reminding method, device and ultrasonic devices, can drop significantly
Low doctor simplifies the behaviour that doctor carries out ultrasonic contrast to the degree of concern of contrast agent perfusion developing time in contrastographic picture
Make, so as to improve the efficiency that doctor checks diagnosis.
In order to solve the above technical problems, the present invention provides a kind of Contrast-enhanced ultrasonography reminding method, the method includes：
In Contrast-enhanced ultrasonography, the contrast agent developed image in contrast agent development flow process is obtained in real time；
When the developed image meets preset calibrations point decision condition, then the prompting letter of corresponding preset calibrations point is generated
Breath, and export the prompt message.
Optionally, the preset calibrations point terminates for development peak or development.
Optionally, it is described when the developed image meets preset calibrations point decision condition, then generate corresponding preset calibrations
The prompt message of point, including：
It calculates in the first continuous predetermined quantity frame number per the gray value of frame contrast agent developed image；；
Whether the gray value for judging the intermediate frame developed image of the described first continuous predetermined quantity frame number is maximum value；
If so, determine that the preset calibrations point for development peak, generates first prompt message on the development peak.
Optionally, it is described when the developed image meets preset calibrations point decision condition, then generate corresponding preset calibrations
The prompt message of point, including：
Calculate the gray value of every frame contrast agent developed image of the second continuous predetermined quantity frame number；
Judge whether the gray value of the intermediate frame contrast agent developed image of the described second continuous predetermined quantity frame number is minimum, and
The gray value of the gray value of every frame contrast agent developed image after the intermediate frame and the contrast agent developed image of intermediate frame
Within a preset range whether difference；
If it is, it is determined that the preset calibrations point terminates for development, generates the second prompt message that the development terminates.
Optionally, the prompt message is exported, including：
Export information of voice prompt.
Optionally, in Contrast-enhanced ultrasonography, the contrast agent developed image in contrast agent development flow process is obtained in real time,
Including：
Target position information input by user is received, and the concern area of ultrasonic contrast is determined according to the target position information
Domain；
In Contrast-enhanced ultrasonography, contrast agent of the contrast agent in the region-of-interest develops flow process is obtained in real time and is shown
Shadow image.
Optionally, the calculation of the gray value of the contrast agent developed image, including：
The contrast agent developed image is subjected to image gray processing processing and image binaryzation processing, is schemed after being handled
Picture；
The gray value of pixel each in image after the processing is added to obtain the gray scale of the contrast agent developed image
Value.
The present invention also provides a kind of Contrast-enhanced ultrasonography suggestion device, described device includes：
Real-time acquisition module, in Contrast-enhanced ultrasonography, obtaining the radiography in contrast agent development flow process in real time
Agent developed image；
Reminding module is exported, it is corresponding pre- for when the developed image meets preset calibrations point decision condition, then generating
The prompt message of fixed point is marked with, and exports the prompt message.
Optionally, the real-time detection module, including：
Region-of-interest determination unit for receiving target position information input by user, and is believed according to the target location
Breath determines the region-of-interest of ultrasonic contrast；
The real-time acquiring unit shows in Contrast-enhanced ultrasonography, obtaining contrast agent in real time in the region-of-interest
Contrast agent developed image in shadow flow process.
The present invention also provides a kind of ultrasonic device, including：
Processor, in Contrast-enhanced ultrasonography, obtaining the contrast agent development in contrast agent development flow process in real time
Image；When the developed image meets preset calibrations point decision condition, then the prompt message of corresponding preset calibrations point is generated；
Output device, for exporting the prompt message.
A kind of Contrast-enhanced ultrasonography reminding method provided by the present invention, including：In Contrast-enhanced ultrasonography, obtain in real time
Contrast agent developed image in contrast agent development flow process；When the developed image meets preset calibrations point decision condition,
Then generate the prompt message of corresponding preset calibrations point, and the output prompt message.
As it can be seen that this method is by setting preset calibrations point, and whether reached in automatic decision contrast agent development flow process
Corresponding preset calibrations point, and the automatic prompt doctor when reaching so that doctor can determine contrast agent in patient in time
At the time of flowing developing time and reach the corresponding stage.Therefore doctor can be substantially reduced to contrast agent perfusion in contrastographic picture
The degree of concern of developing time, and then simplify the operation that doctor carries out ultrasonic contrast, so as to improve the efficiency that doctor checks diagnosis.
The present invention also provides a kind of Contrast-enhanced ultrasonography device and ultrasonic devices, have above-mentioned advantageous effect, details are not described herein.
Description of the drawings
In order to illustrate more clearly about the embodiment of the present invention or technical scheme of the prior art, to embodiment or will show below
There is attached drawing needed in technology description to be briefly described, it should be apparent that, the accompanying drawings in the following description is only this
The embodiment of invention, for those of ordinary skill in the art, without creative efforts, can also basis
The attached drawing of offer obtains other attached drawings.
The flow chart of Contrast-enhanced ultrasonography reminding method that Fig. 1 is provided by the embodiment of the present invention；
The flow chart on judgement development peak that Fig. 2 is provided by the embodiment of the present invention；
The flow chart that Fig. 3 is terminated by the judgement development that the embodiment of the present invention provides；
Fig. 4 is illustrated by a kind of specific flow for judging development peak that the embodiment of the present invention provides；
Fig. 5 is illustrated by a kind of specific flow for judging that development terminates that the embodiment of the present invention provides；
The structure diagram of Contrast-enhanced ultrasonography device that Fig. 6 is provided by the embodiment of the present invention；
The structure diagram for the ultrasonic device that Fig. 7 is provided by the embodiment of the present invention.
Specific embodiment
A kind of Contrast-enhanced ultrasonography reminding method provided in an embodiment of the present invention is explained below, by setting preset calibrations
Point, and corresponding preset calibrations point whether is reached in automatic decision contrast agent development flow process, and automatic prompt is cured when reaching
It is raw；Degree of concern of the doctor to contrast agent perfusion developing time in contrastographic picture can be reduced, diagnosis is checked so as to improve doctor
Efficiency.
Purpose, technical scheme and advantage to make the embodiment of the present invention are clearer, below in conjunction with the embodiment of the present invention
In attached drawing, the technical solution in the embodiment of the present invention is clearly and completely described, it is clear that described embodiment is
Part of the embodiment of the present invention, instead of all the embodiments.Based on the embodiments of the present invention, those of ordinary skill in the art
All other embodiments obtained without making creative work shall fall within the protection scope of the present invention.
The present embodiment is based on the basis of the monitoring of current radiography, by being made when machine control time in itself and contrast examination
The time showing of different phases during shadow start to finish, is associated the infusion time at different phases to organs and tissues position,
And different phases are made with prompting, assist the resolution for reminding doctor to observing phase；Improve effect when doctor checks.Specifically please
With reference to figure 1, the flow chart of Contrast-enhanced ultrasonography reminding method that Fig. 1 is provided by the embodiment of the present invention；This method can include：
S110, in Contrast-enhanced ultrasonography, in real time obtain contrast agent development flow process in contrast agent developed image；
S120, when the developed image meets preset calibrations point decision condition, then generate carrying for corresponding preset calibrations point
Show information, and export the prompt message.
If it is unsatisfactory for preset calibrations point and sentences after the present embodiment judges the detection of the contrast agent developed image of present frame
Fixed condition then continues to be detected the contrast agent developed image of next frame in contrast agent development flow process and whether judges it
Meet preset calibrations point decision condition.The above process can be no longer performed after all preset calibrations points are prompted.
In Contrast-enhanced ultrasonography, that is, activate and contrast agent is injected while radiography function, start Contrast-enhanced ultrasonography simultaneously
Contrast agent starts to flow.Doctor needs to observe the process of contrast agent development at this time.The process of contrast agent development includes：From without to opening
Begin development, gradually enhance, to most strong, then start to subside, to the last subside completely.According to the difference at radiography position, Yi Shengxu
It the calibration point position to be paid close attention to may be different.Need the calibration point paid close attention to that can include under normal circumstances：Development starts, development
Peak, development end etc..Therefore, the present embodiment is not defined the content of preset calibrations point, can will be general several
A calibration point is set as preset calibrations point；It can also be self-defined default according to the practical radiography demand at the organs and tissues position of radiography
Calibration point.In Contrast-enhanced ultrasonography, in order to doctor can determine in time flowing developing time of the contrast agent in patient with
And at the time of reaching the corresponding stage, degree of concern of the doctor to contrast agent perfusion developing time in contrastographic picture is reduced, so as to carry
Gao doctor checks the efficiency of diagnosis.Usual doctor can compare concern development peak and development terminates, it is preferred, therefore, that this implementation
Preset calibrations point terminates for development peak or development in example.
Optionally, described when the developed image meets preset calibrations point decision condition, then corresponding pre- bidding is generated
Before the prompt message of fixed point, the method can also include：Pre-set preset calibrations point and its corresponding preset calibrations point
Decision condition.
For example, the present embodiment determines this radiography before can entering ultrasonic contrast functional mode before radiography function is activated
The calibration point prompted is needed as preset calibrations point, and determines the corresponding preset calibrations point judgement item of each preset calibrations point
Part.Pass through the detection and analysis to contrast agent developed image in contrast agent develops flow process in this way, it is possible to determine present frame
Contrast agent developed image whether be preset calibrations point, and when the contrast agent developed image of present frame is corresponding at the time of correspond to
It is prompted when being carved into up to preset calibrations point.Started below with development, peak of developing, development terminates these three calibration points as pre-
Illustrate the detailed process of the present embodiment for bidding fixed point：
Contrast agent is injected while activating radiography function, contrast agent starts to flow, when contrast agent reaches region-of-interest development
When, the contrast agent developed image of each frame in contrast agent development flow process is detected in real time, judges contrast agent development figure
Whether occurs contrast agent (whether meet development and start decision condition) as in, if then thinking the frame contrast agent developed image pair
I.e. start time proves to reach beginning calibration point at the time of answering.The corresponding prompt message for starting calibration point of generation at this time, and
Prompt message is exported, doctor can know clearly the mobility status of contrast agent development at this time when obtaining the prompt message.And
The contrast agent developed image for continuing each frame in the development flow process of the contrast agent under docking is detected, and judges that contrast agent develops
Whether image reaches the development top moment (whether meeting development peak decision condition), if then thinking that the frame contrast agent is shown
I.e. the top moment proves to reach development peak at the time of shadow image corresponds to.The prompting letter on the corresponding development peak of generation at this time
Breath, and export prompt message.And continue the lower contrast agent of docking develop each frame in flow process contrast agent developed image into
Row detection, judges whether contrast agent developed image reaches finish time (whether meet development and terminate decision condition), if then
Think that i.e. finish time proves that reaching development terminates at the time of the frame contrast agent developed image corresponds to.Generation at this time is corresponding aobvious
The prompt message that shadow terminates, and export prompt message.
The present embodiment emphasis is to be when judging that a certain frame contrast agent developed image has reached some preset calibrations point, then
Prompt message is exported to remind doctor note that so as to which doctor is contributed to pass through the prompting of output when observing contrastographic picture
Information (such as information of voice prompt) assists the resolution for reminding doctor to observing phase, that is, preset calibrations point, improves doctor and checks
When effect.Therefore, the present embodiment does not limit the particular content of each specific preset calibrations point decision condition, i.e., unlimited
The used specific detection method of the step for determining the contrast agent developed image in real-time contrast agent detection development flow process.
As long as it can determine whether a certain frame contrast agent developed image has reached some preset calibrations point by used mode.
User can select according to adaptations such as the hardware conditions of the ultrasonic device of actual use.
Further, due to not limiting the particular content of preset calibrations point decision condition, i.e., specific pre- bidding is not limited
Pinpoint the judgement form of decision condition.It can be after the detection to contrast agent developed image, by testing result and each
The corresponding preset calibrations point decision condition of preset calibrations point is all compared judgement to confirm whether it reaches some pre- bidding
Fixed point.For example, it may be after the detection to contrast agent developed image, testing result is started respectively with development decision condition,
Development peak decision condition and development terminate decision condition and are all compared judgement, see it is which preset calibrations point belonged to
Or it is all not belonging to.It can also be that the sequencing to arrive according to preset calibrations point is ranked up, according to clooating sequence, compare successively
Whether belong to the corresponding preset calibrations point of preset calibrations point compared before this compared with the contrast agent developed image judged after detecting
Decision condition.Judge whether to meet after the detection of contrast agent developed image in the flow process that develops to contrast agent in the present embodiment
During preset calibrations point decision condition, in order to improve judgement speed, calculation amount is reduced.It is only corresponding with current time default at this time
Calibration point decision condition is compared judgement.
Below with development start, develop peak, development terminate these three calibration points as illustrate for preset calibrations point originally
The detailed process of embodiment：The judgement sequence of each preset calibrations point decision condition is determined first；I.e. first judges that development starts
Decision condition, second judges development peak decision condition, and third judges that development terminates decision condition.Secondly it is suitable according to judging
Sequence first carries out the detection by contrast agent developed image in the flow process that develops in real time to contrast agent, judges whether that meeting development opens
Beginning decision condition；If satisfied, then transferring the prompt message that corresponding development starts, and export prompt message.It is opened reaching development
Development peak decision condition is chosen after beginning as basis for estimation, passes through radiography in the flow process that develops in real time to following contrast agent
The detection of agent developed image judges whether to meet development peak decision condition；If satisfied, then transfer the prompting on corresponding development peak
Information, and export prompt message.Development is chosen after development peak is reached and terminates decision condition as basis for estimation, passes through reality
When to following contrast agent develop flow process in contrast agent developed image detection, judge whether meet development terminate judgement item
Part；If satisfied, then transferring the prompt message that corresponding development terminates, and export prompt message.Judged successively by judgement sequence
Mode can improve every time to the contrast agent developed image judging efficiency after detection, improve and determine setting calibration point constant speed really
Degree.Improve the promptness of output prompt message.
In the present embodiment, however, it is determined that the corresponding contrast agent developed image of present frame reaches some at the time of correspondence default
During calibration point, need to export the corresponding output information of preset calibrations point, so that doctor is reminded to pay attention to.Therefore, as long as reaching
Prompt message is exported during some preset calibrations points in time and reminds doctor.The present embodiment is not to the specific of prompt message
Setting is defined.Such as each preset calibrations point can correspond to same prompt message or each is default
Calibration point all has its specific prompt message, such as development starts corresponding beginning prompt message, and development peak carries Ying Gaofeng
Show information, development terminates corresponding end prompt message.Equally, the particular content of prompt message can also voluntarily be set by user,
Or it is configured to facilitate its identification by doctor.The present embodiment is not defined this.
Further, the present embodiment does not also limit the specific output form of output prompt message.Such as can be voice prompt,
Can be text prompt or indicator light prompting.The present embodiment does not limit the specific implementation form of each output form yet.
For example, in voice prompt can by voice reading characters content come export or by different sound numbers come
Prompting.It can be exported in text prompt by pop-up to export or by annotating frame.It is timely for the ease of doctor
Clearly obtain prompt message, it is preferred that the present embodiment exports information of voice prompt.Assisted by exporting information of voice prompt
The resolution for reminding doctor to observing phase is helped, improves effect when doctor checks.Such as during the flowing by developing to contrast agent
Between different phase calibration, that is, multiple preset calibrations point (setting alternative sounds prompt tone), can help to check that doctor is more convenient
Make diagnosis, be also beneficial to simplify doctor operating process.
Based on above-mentioned technical proposal, Contrast-enhanced ultrasonography reminding method that the embodiment of the present invention carries passes through the pre- bidding of setting
Fixed point, and corresponding preset calibrations point, and the automatic prompt when reaching whether are reached in automatic decision contrast agent development flow process
Doctor therefore, it is possible to substantially reduce degree of concern of the doctor to contrast agent perfusion developing time in contrastographic picture, and then simplifies doctor
The raw operation for carrying out ultrasonic contrast, so as to improve the efficiency that doctor checks diagnosis.
Since doctor needs flowing developing time of the contrast agent in patient (being based on as the foundation to diagnose the illness
The contrast agent time that normal perfusion flows in the organs and tissues of required observation is as under basis for estimation premise background), thus it is defeated
Go out that prompt message is more timely, closer to the diagnosis for being more conducive to disease simultaneously.I.e. when reaching some preset calibrations point just
It exports simultaneously under the situation of prompt message at once, it, also just can be more at the time of doctor can more accurately obtain each stage and correspond to
Add and accurately diagnose the illness.Accuracy and reliability of the promptness of further prompt message output dependent on positioning.I.e.
Need determining for the preset calibrations points such as the time starting point developed during proper flow in internal organs to contrast agent, high peak dot, end point
Position accuracy has certain requirement, these can influence the result of actual observation.
Therefore it based on above-mentioned any embodiment, specifically please refers to Fig.2, present embodiments provides developed image and meet pre- bidding
When pinpointing decision condition, then generating the prompt message of corresponding preset calibrations point can include：
It please refers to Fig.2, the flow chart on judgement development peak that Fig. 2 is provided by the embodiment of the present invention；The process can wrap
It includes：
S210, it calculates in the first continuous predetermined quantity frame number per the gray value of frame contrast agent developed image；
Whether S220, the gray value of intermediate frame developed image for judging the described first continuous predetermined quantity frame number are maximum
Value；
S230, if so, determine the preset calibrations point for development peak, generation development peak the first prompt message；
S240, if it is not, then judge be not development peak.
The present embodiment is by judging contrast agent developed image gray value come at the time of finding out contrast imaging development peak.Its
In, the concrete numerical value of the first continuous predetermined quantity frame number is not limited in the present embodiment.The quantity for selecting successive frame is more, judgement
More accurate, corresponding take can also increase, i.e., the judgement on perfusion development peak is relied on ultrasonic device image operation frame frequency and
Display frame frequency, otherwise prompt message and practical developed image have certain interval time difference, when the interval time difference is excessive not
Can accomplish real-time prompting, can only freeze playback when ability real-time prompting.It needs to be carried out according to the computing capability of actual hardware true
It is fixed.Combining accuracy and promptness, it is preferred that the first continuous predetermined quantity frame number is to meet the maximum frame number checked.Example
Continuous 7 frame contrast agent developed image can be chosen as the computing capability according to current ultrasonic device, calculates each frame respectively
The corresponding gray value of contrast agent developed image.When the corresponding gray value of present frame contrast agent developed image is maximum value, you can
With determine present frame corresponds at the time of i.e. development peak at the time of.The first continuous predetermined quantity is in before present frame under normal circumstances
The centre position of frame number.Therefore the first continuous predetermined quantity can be with selected as odd number.Such as choose continuous 7 frame contrast agent development figure
Picture, present frame are the position in the 4th frame.
Therefore it based on above-mentioned any embodiment, specifically please refers to Fig.3, present embodiments provides developed image and meet pre- bidding
When pinpointing decision condition, then generating the prompt message of corresponding preset calibrations point can include：
S310, calculate the second continuous predetermined quantity frame number every frame contrast agent developed image gray value；
S320, judge the described second continuous predetermined quantity frame number intermediate frame contrast agent developed image gray value whether most
It is small, and the gray scale of the contrast agent developed image of the gray value and intermediate frame of every frame contrast agent developed image after the intermediate frame
Within a preset range whether the difference of value；
If S330, being, determine that the preset calibrations point terminates for development, the second prompt message that generation development terminates；
If not S340, being, judgement is not that development terminates.
At the time of the present embodiment is terminated by judging contrast agent developed image gray value to find out contrast imaging development.Its
In, the concrete numerical value of the second continuous predetermined quantity frame number is not limited in the present embodiment.It can be according to the calculating of actual hardware
Ability is determined.The quantity for selecting successive frame is more, and judgement is more accurate, and corresponding take can also increase, i.e., development is terminated
Judgement rely on ultrasonic device image operation frame frequency and display frame frequency, otherwise can extend the review time.In order to improve detection effect
Rate is combining accuracy and promptness, it is preferred that the second continuous predetermined quantity frame number is to meet the maximum frame number checked.Example
Continuous 7 frame contrast agent developed image can be chosen as the computing capability according to current ultrasonic device, calculates each frame respectively
The corresponding gray value of contrast agent developed image.Present frame is in the centre position of successive frame under normal circumstances.Therefore second is continuous
Predetermined quantity can be with selected as odd number.Such as continuous 7 frame contrast agent developed image is chosen, present frame is the position in the 4th frame.
The concrete numerical value of preset range is not limited in the present embodiment, can be a minimum, approximation is interpreted as not having, thus
It can represent in the contrast agent developed image that this thing obtains substantially without contrast agent.I.e. angiographic procedure can terminate.
Here decision condition can be understood as assuming continuous N frames, and N is odd number, and intermediate frame is the frame of (N+1)/2, that
Judge that the condition that development terminates is：In continuous N frame images, in the preceding frame image of (N+1)/2 the frame gradation of image of (N+1)/2 and
Minimum, the rear frame image of (N+1)/2, per frame gradation of image and with the frame gradation of image of (N+1)/2 and absolute value of the difference | a | be less than
δ。
For start mark point judgement, can directly will injection contrast agent at the time of as start time.
The first prompt message and the second prompt message can be different prompt message in the present embodiment.
The present embodiment can be improved every time by the improvement of calibration point judgment mode to the contrast agent developed image after detection
Judging efficiency and accuracy improve the reliability for determining setting calibration point.Improve the promptness of output prompt message.
The calculation of the corresponding gray value of contrast agent developed image is not defined, please referred in above-described embodiment
Fig. 4 and Fig. 5, based on above-described embodiment, the calculation of the gray value of contrast agent developed image can include：
The contrast agent developed image is subjected to image gray processing processing and image binaryzation processing, is schemed after being handled
Picture；
The gray value of pixel each in image after the processing is added to obtain the gray scale of the contrast agent developed image
Value.
Wherein, image gray processing is that coloured image is transformed into the process of gray level image to be known as at the gray processing of image
Reason.The color of each pixel in coloured image has tri- components of R, G, B to determine, and each component has 255 intermediate values can use, in this way
One pixel can have the variation range of the color of more than 1,600 ten thousand (255*255*255).And gray level image is tri- points of R, G, B
A kind of identical special coloured image is measured, the variation range of one pixel is 255 kinds, so in Digital Image Processing kind
It is general that the image of various forms is first transformed into gray level image so that the calculation amount of subsequent image becomes few.Gray level image
Description still reflected as coloured image entire image entirety and part coloration and brightness degree distribution and spy
Sign.Arithmetic speed can be greatly improved in this way.Mean value method may be used to realize in gray processing processing in the present embodiment.Ask
Go out the average value of tri- components of R, G, B of each pixel, then this average value is given to three components of this pixel.
Specific formula is as follows：Wherein, Gray (i, j) is the gray value of each pixel.Gray (i, j)=(R (i, j)+G (i, j)+B
(i,j))/3。
Wherein, image binaryzation be by the gray value of pixel on image by appropriate threshold value selection be set as 0 or
255, for reflecting image entirety and local feature.Kittle algorithms may be used in image binaryzation processing in the present embodiment,
The average value of the gradient gray scale of entire image is calculated, using average value as threshold value.255 are set as more than threshold value in image, is less than
Threshold value is set as 0.Image binaryzation also plays the effect of removal partial noise.User can select to carry out according to actual conditions
Binary conversion treatment or without binary conversion treatment.Preferably, a switch can be set in the present embodiment, and commissioning staff is optional
Select be turned on or off the switch carry out realize perform image binaryzation processing and do not perform image binaryzation processing.
Due to contrast agent, some tissue is bigger during perfusion, and doctor concern region it is smaller or
It is the possible more than one of tissue that it passes through, at this time it is possible that multiple preset calibrations point is prompted during being prompted
(i.e. the perfusion of contrast agent normal tissue also has peak period), such as the prompting of development peak.Doctor is also noted that one at this time
It is lower its whether be normal structure prompt message.Doctor can not be made easily to get key message.Therefore in order to ensure to carry
Show the key of information, do not reresent irrelevant information.Can increase can accurately distinguish be in lesion tissue developer pay close attention to it is pre-
The technological means of development preset calibrations point in bidding fixed point (such as peak of developing) or normal structure.
Preferably, based on above-mentioned any embodiment, the present embodiment obtains contrast agent development in real time in Contrast-enhanced ultrasonography
Contrast agent developed image in flow process includes：
Target position information input by user is received, and the concern area of ultrasonic contrast is determined according to the target position information
Domain；
In Contrast-enhanced ultrasonography, contrast agent of the contrast agent in the region-of-interest develops flow process is obtained in real time and is shown
Shadow image.
Specifically, the present embodiment is by determining that region-of-interest, such as doctor choose focal area as region-of-interest in advance,
Subsequent prompt message is only for the prompting of preset calibrations point in region-of-interest.I.e. after the region-of-interest of ultrasonic contrast is determined,
Under ultrasonic contrast functional mode, contrast agent of the real-time contrast agent detection in the region-of-interest develops flow process, which develops, schemes
Picture；When the developed image meets preset calibrations point decision condition, then the prompt message of corresponding preset calibrations point is generated, and defeated
Go out the prompt message.
The form of input target position information is not limited in the present embodiment.Such as user can be arrived by motion track ball
Corresponding lesion tissue position determines the region-of-interest of ultrasonic contrast.Or region-of-interest frame is determined (here not by click
Limit the shape of the region-of-interest frame, for example, rectangle) starting point, and dragged and drawing direction zooms in or out concern
The size of regional frame finally determines the region-of-interest of ultrasonic contrast.
The selection mode of specific target position information input by user is not limited in the present embodiment.Such as can be true
Enter the selected function of region-of-interest when entering radiography function surely；Either user is by selecting region-of-interest selection key, really
Surely enter the selected function of region-of-interest.Such as radiography function key is clicked, into preactivate radiography function.The present embodiment is simultaneously unlimited
Determine the quantity of region-of-interest, under normal circumstances, carry out only selecting a region-of-interest during ultrasonic contrast every time.
It further, can (can also in the activation instruction for receiving user in order to ensure the accuracy of region-of-interest selection
It is interpreted as confirming instruction) activation region-of-interest (can be interpreted as finally determining that the region is region-of-interest).Such as it clicks and makes
Shadow function key into preactivate radiography function, clicks specific operation key, activates region-of-interest.
Further, selected region-of-interest is changed in order to facilitate user, before the activation instruction of user is received, used
Family can arbitrarily change region-of-interest.Such as user, when selecting second region-of-interest, first region-of-interest is just substituted.
Or instruction is cancelled in input, cancels region-of-interest chosen before etc..
The implementation procedure of above-described embodiment is exemplified below：
1st, normal ultrasonic examination flow：Click diagnostic mode selection key, into B-mode normal inspection, what scanning need to check
Internal organs position and region-of-interest.
2nd, radiography function key is clicked, into preactivate radiography function, clicks specific operation key, selected region-of-interest is swept
Look into region-of-interest (such as abdomen liver and abnormal footprint), activation concern area (such as with special interest frame to internal organs group
Abnormal occupy-place area (such as liver inner disease foci lump) in knitting carries out mark and forms region-of-interest).
3rd, contrast agent is injected, while activates radiography function, into contrast examination.
When the 4th, activating radiography function, (time that record contrast agent starts injection starts calibration point, defeated for synchronous beginning timing
Go out to start prompt message).
5th, the process of observation contrast agent development particularly pays close attention to the development in area, from without to beginning to focus on, gradually enhances,
To most strong (reaching development peak, output peak prompt message can be understood as the first prompt message), then start to subside, until most
When subsiding completely (reach development to terminate, end of output prompt message can be understood as the second prompt message) afterwards, and recording development
Between, slowly subside from starting to maximum, then from maximum.
By the selection of region-of-interest in the present embodiment, the default of doctor's region-of-interest (generally focal area) is only prompted
Calibration point can improve the efficiency that doctor obtains information；Doctor can be substantially reduced to develop to contrast agent perfusion in contrastographic picture
The degree of concern of time, and then simplify the operation that doctor carries out ultrasonic contrast, so as to improve the efficiency that doctor checks diagnosis.
Contrast-enhanced ultrasonography device provided in an embodiment of the present invention and ultrasonic device are introduced below, it is described below
Contrast-enhanced ultrasonography device and ultrasonic device can correspond reference with above-described Contrast-enhanced ultrasonography reminding method.
Please refer to Fig. 6, the structure diagram of Contrast-enhanced ultrasonography device that Fig. 6 is provided by the embodiment of the present invention；The device
It can include：
Real-time acquisition module 100, in Contrast-enhanced ultrasonography, obtaining making in contrast agent development flow process in real time
Shadow agent developed image；
Reminding module 200 is exported, for when the developed image meets preset calibrations point decision condition, then generating correspondence
The prompt message of preset calibrations point, and export the prompt message.
Based on above-described embodiment.Real-time acquisition module, including：
Region-of-interest determination unit for receiving target position information input by user, and is believed according to the target location
Breath determines the region-of-interest of ultrasonic contrast；
Real-time acquiring unit flows in Contrast-enhanced ultrasonography, obtaining contrast agent in real time in region-of-interest development
Contrast agent developed image during dynamic.
It should be noted that based on above-mentioned any embodiment, Contrast-enhanced ultrasonography device can be based on programmable logic
What device was realized, programmable logic device includes FPGA, CPLD, microcontroller etc..
Please refer to Fig. 7, the structure diagram for the ultrasonic device that Fig. 7 is provided by the embodiment of the present invention；The ultrasonic device can be with
Including：
Processor 400 shows in Contrast-enhanced ultrasonography, obtaining the contrast agent in contrast agent development flow process in real time
Shadow image；When the developed image meets preset calibrations point decision condition, then the prompt message of corresponding preset calibrations point is generated；
Output device 500, for exporting the prompt message.
Based on above-described embodiment, it is preferred that output device 500 can be voice output component, for exporting voice prompt
Information.Such as voice output component can be sound equipment, loudspeaker etc..
Each embodiment is described by the way of progressive in specification, the highlights of each of the examples are with other realities
Apply the difference of example, just to refer each other for identical similar portion between each embodiment.For device disclosed in embodiment
Speech, since it is corresponded to the methods disclosed in the examples, so description is fairly simple, related part is referring to method part illustration
.
Professional further appreciates that, with reference to each exemplary unit of the embodiments described herein description
And algorithm steps, can be realized with the combination of electronic hardware, computer software or the two, in order to clearly demonstrate hardware and
The interchangeability of software generally describes each exemplary composition and step according to function in the above description.These
Function is performed actually with hardware or software mode, specific application and design constraint depending on technical solution.Profession
Technical staff can realize described function to each specific application using distinct methods, but this realization should not
Think beyond the scope of this invention.
It can directly be held with reference to the step of method or algorithm that the embodiments described herein describes with hardware, processor
The combination of capable software module or the two is implemented.Software module can be placed in random access memory (RAM), memory, read-only deposit
Reservoir (ROM), electrically programmable ROM, electrically erasable ROM, register, hard disk, moveable magnetic disc, CD-ROM or technology
In any other form of storage medium well known in field.
A kind of Contrast-enhanced ultrasonography reminding method provided by the present invention, device and ultrasonic device have been carried out in detail above
It introduces.Specific case used herein is expounded the principle of the present invention and embodiment, the explanation of above example
It is merely used to help understand the method and its core concept of the present invention.It should be pointed out that the ordinary skill people for the art
Member for, without departing from the principle of the present invention, can also to the present invention some improvement and modification can also be carried out, these improve and
Modification is also fallen within the protection scope of the claims of the present invention.
Claims (10)
1. a kind of Contrast-enhanced ultrasonography reminding method, which is characterized in that the method includes：
In Contrast-enhanced ultrasonography, the contrast agent developed image in contrast agent development flow process is obtained in real time；
When the developed image meets preset calibrations point decision condition, then the prompt message of corresponding preset calibrations point is generated, and
Export the prompt message.
2. according to the method described in claim 1, it is characterized in that, preset calibrations point terminates for development peak or development.
It is 3. according to the method described in claim 1, it is characterized in that, described when the developed image meets the judgement of preset calibrations point
During condition, then the prompt message of corresponding preset calibrations point is generated, including：
It calculates in the first continuous predetermined quantity frame number per the gray value of frame contrast agent developed image；
Whether the gray value for judging the intermediate frame developed image of the described first continuous predetermined quantity frame number is maximum value；
If so, determine that the preset calibrations point for development peak, generates first prompt message on the development peak.
It is 4. according to the method described in claim 1, it is characterized in that, described when the developed image meets the judgement of preset calibrations point
During condition, then the prompt message of corresponding preset calibrations point is generated, including：
Calculate the gray value of every frame contrast agent developed image of the second continuous predetermined quantity frame number；
Judge whether the gray value of the intermediate frame contrast agent developed image of the described second continuous predetermined quantity frame number is minimum and described
The difference of the gray value of the gray value of every frame contrast agent developed image after intermediate frame and the contrast agent developed image of intermediate frame
Whether within a preset range；
If it is, it is determined that the preset calibrations point terminates for development, generates the second prompt message that the development terminates.
5. according to the method described in claim 1, it is characterized in that, export the prompt message, including：
Export information of voice prompt.
6. according to claim 1-5 any one of them methods, which is characterized in that it is described in Contrast-enhanced ultrasonography, it obtains in real time
The contrast agent developed image in contrast agent development flow process is taken, including：
Target position information input by user is received, and the region-of-interest of ultrasonic contrast is determined according to the target position information；
In Contrast-enhanced ultrasonography, contrast agent development figure of the contrast agent in the region-of-interest develops flow process is obtained in real time
Picture.
7. the according to the method described in claim 1, it is characterized in that, calculating side of the gray value of the contrast agent developed image
Formula, including：
The contrast agent developed image is subjected to image gray processing processing and image binaryzation processing, image after being handled；
The gray value of pixel each in image after the processing is added to obtain the gray value of the contrast agent developed image.
8. a kind of Contrast-enhanced ultrasonography suggestion device, which is characterized in that described device includes：
Real-time acquisition module shows in Contrast-enhanced ultrasonography, obtaining the contrast agent in contrast agent development flow process in real time
Shadow image；
Reminding module is exported, for when the developed image meets preset calibrations point decision condition, then generating corresponding pre- bidding
The prompt message of fixed point, and export the prompt message.
9. device according to claim 8, which is characterized in that the real-time detection module, including：
Region-of-interest determination unit, for receiving target position information input by user, and it is true according to the target position information
Determine the region-of-interest of ultrasonic contrast；
The real-time acquiring unit flows in Contrast-enhanced ultrasonography, obtaining contrast agent in real time in region-of-interest development
Contrast agent developed image during dynamic.
10. a kind of ultrasonic device, which is characterized in that including：
Processor, in Contrast-enhanced ultrasonography, obtaining the contrast agent developed image in contrast agent development flow process in real time；
When the developed image meets preset calibrations point decision condition, then the prompt message of corresponding preset calibrations point is generated；
Output device, for exporting the prompt message.
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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