CN108117756A - A kind of intrauterine device and preparation method thereof - Google Patents
A kind of intrauterine device and preparation method thereof Download PDFInfo
- Publication number
- CN108117756A CN108117756A CN201711426570.7A CN201711426570A CN108117756A CN 108117756 A CN108117756 A CN 108117756A CN 201711426570 A CN201711426570 A CN 201711426570A CN 108117756 A CN108117756 A CN 108117756A
- Authority
- CN
- China
- Prior art keywords
- silica gel
- taken
- intrauterine device
- crosslinking agent
- mixing machine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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Classifications
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- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08K—Use of inorganic or non-macromolecular organic substances as compounding ingredients
- C08K3/00—Use of inorganic substances as compounding ingredients
- C08K3/02—Elements
- C08K3/08—Metals
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08K—Use of inorganic or non-macromolecular organic substances as compounding ingredients
- C08K3/00—Use of inorganic substances as compounding ingredients
- C08K3/02—Elements
- C08K3/08—Metals
- C08K2003/085—Copper
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08K—Use of inorganic or non-macromolecular organic substances as compounding ingredients
- C08K2201/00—Specific properties of additives
- C08K2201/011—Nanostructured additives
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L2312/00—Crosslinking
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- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Polymers & Plastics (AREA)
- Organic Chemistry (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
The invention discloses a kind of intrauterine device and preparation method thereof, a kind of intrauterine device with silica gel, copper nanoparticle, crosslinking agent by being prepared；By raw material proportioning silica gel is taken to be put into rubber mixing machine to be kneaded；Copper nanoparticle is taken to be gradually added in silica gel to be uniformly mixed；Crosslinking agent is taken to be added in rubber mixing machine, forms colloid mixture；Colloid mixture is put into mold, heating compacting is made after finished product and carries out aging, sterilizing according to health care requirement again, disinfects.Birth control ring surface of the present invention is smooth, and soft texture is flexible, nonirritant with human contact, will not be combined with human contact with human body, will not cause bleeding, pain.
Description
Technical field
The present invention relates to medical fields, are specifically a kind of intrauterine device and preparation method thereof.
Background technology
Market existing product is to be made of silica gel after knot educates ring, then winds or be wrapped in the silicon being made by copper ring or copper wire
On the cementing surface for educating ring, from lower and existing contraceptive effect.But rough, pliability is bad, and elasticity is bad, with human contact
It is irritant, the shortcomings of being combined with human contact with human body, bleeding, pain can be caused.
Knot also educates the drug added in ring, and the knot of drug has been added to educate ring, just without contraception after drug volatilization is complete
Effect, service life is too short, rough, and pliability is bad, and elasticity is bad, irritant with human contact, with human contact
The shortcomings of being combined with human body, bleeding, pain can be caused.
The content of the invention
It is mentioned above in the background art to solve it is an object of the invention to provide a kind of intrauterine device and preparation method thereof
Problem.
To achieve the above object, the present invention provides following technical solution：
A kind of intrauterine device is prepared by the raw material of following mass parts：70~80 parts of silica gel, 20~30 parts of copper nanoparticle,
2~3 parts of crosslinking agent.
A kind of preparation method of intrauterine device, specific preparation process are as follows：
1) by above-mentioned raw materials proportioning silica gel is taken to be put into rubber mixing machine to be kneaded；
2) by above-mentioned raw materials proportioning copper nanoparticle is taken to be gradually added in silica gel to be uniformly mixed；
3) by above-mentioned raw materials proportioning crosslinking agent is taken to be added in rubber mixing machine, forms colloid mixture；
4) above-mentioned colloid mixture is put into mold, heating compacting, the temperature of mold heating is 160~180 degree, heats compacting
Time is 5~10 minutes, is made after finished product and carries out aging, sterilizing according to health care requirement again, disinfects.
Compared with prior art, the beneficial effects of the invention are as follows：Birth control ring surface of the present invention is smooth, and soft texture has bullet
Property, it is nonirritant with human contact, it will not be combined with human contact with human body, bleeding, pain will not be caused.
Specific embodiment
Below in conjunction with the embodiment of the present invention, the technical solution in the embodiment of the present invention is clearly and completely described,
Obviously, described embodiment is only part of the embodiment of the present invention, instead of all the embodiments.Based in the present invention
Embodiment, those of ordinary skill in the art's all other embodiments obtained without making creative work,
Belong to the scope of protection of the invention.
Embodiment 1
A kind of intrauterine device is prepared by the raw material of following mass parts：80 parts of silica gel, 30 parts of copper nanoparticle, crosslinking agent 3
Part.
The preparation process of intrauterine device is as follows in above-described embodiment：
1) by above-mentioned raw materials proportioning silica gel is taken to be put into rubber mixing machine to be kneaded；
2) by above-mentioned raw materials proportioning copper nanoparticle is taken to be gradually added in silica gel to be uniformly mixed；
3) by above-mentioned raw materials proportioning crosslinking agent is taken to be added in rubber mixing machine, forms colloid mixture；
4) above-mentioned colloid mixture is put into mold, heating compacting, the temperature of mold heating is 180 degree, heats the pressing time
For 10 minutes, it is made after finished product and carries out aging, sterilizing according to health care requirement again, disinfect.
Embodiment 2
A kind of intrauterine device is prepared by the raw material of following mass parts：75 parts of silica gel, 25 parts of copper nanoparticle, crosslinking agent 2.5
Part.
The preparation process of intrauterine device is as follows in above-described embodiment：
1) by above-mentioned raw materials proportioning silica gel is taken to be put into rubber mixing machine to be kneaded；
2) by above-mentioned raw materials proportioning copper nanoparticle is taken to be gradually added in silica gel to be uniformly mixed；
3) by above-mentioned raw materials proportioning crosslinking agent is taken to be added in rubber mixing machine, forms colloid mixture；
4) above-mentioned colloid mixture is put into mold, heating compacting, the temperature of mold heating is 170 degree, heats the pressing time
For 8 minutes, it is made after finished product and carries out aging, sterilizing according to health care requirement again, disinfect.
Embodiment 3
A kind of intrauterine device is prepared by the raw material of following mass parts：70 parts of silica gel, 20 parts of copper nanoparticle, crosslinking agent 2
Part.
The preparation process of intrauterine device is as follows in above-described embodiment：
1) by above-mentioned raw materials proportioning silica gel is taken to be put into rubber mixing machine to be kneaded；
2) by above-mentioned raw materials proportioning copper nanoparticle is taken to be gradually added in silica gel to be uniformly mixed；
3) by above-mentioned raw materials proportioning crosslinking agent is taken to be added in rubber mixing machine, forms colloid mixture；
4) above-mentioned colloid mixture is put into mold, heating compacting, the temperature of mold heating is 160 degree, heats the pressing time
For 5 minutes, it is made after finished product and carries out aging, sterilizing according to health care requirement again, disinfect.
It is obvious to a person skilled in the art that the invention is not restricted to the details of above-mentioned exemplary embodiment, Er Qie
In the case of without departing substantially from spirit or essential attributes of the invention, the present invention can be realized in other specific forms.Therefore, nothing
By from the point of view of which point, the present embodiments are to be considered as illustrative and not restrictive, and the scope of the present invention is by institute
Attached claim rather than above description limit, it is intended that will fall within the meaning and scope of the equivalent requirements of the claims
All changes be included within the present invention.
Moreover, it will be appreciated that although this specification is described in terms of embodiments, but not each embodiment is only wrapped
Containing an independent technical solution, this description of the specification is merely for the sake of clarity, and those skilled in the art should
Using specification as an entirety, the technical solutions in each embodiment can also be properly combined, forms those skilled in the art
It is appreciated that other embodiment.
Claims (2)
1. a kind of intrauterine device, which is characterized in that the intrauterine device is prepared by the raw material of following mass parts：Silica gel 70~80
Part, 20~30 parts of copper nanoparticle, 2~3 parts of crosslinking agent.
A kind of 2. preparation method of intrauterine device according to claim 1, which is characterized in that the preparation method of the intrauterine device
It is as follows：
1) by above-mentioned raw materials proportioning silica gel is taken to be put into rubber mixing machine to be kneaded；
2) by above-mentioned raw materials proportioning copper nanoparticle is taken to be gradually added in silica gel to be uniformly mixed；
3) by above-mentioned raw materials proportioning crosslinking agent is taken to be added in rubber mixing machine, forms colloid mixture；
4) above-mentioned colloid mixture is put into mold, heating compacting, the temperature of mold heating is 160~180 degree, heats the pressing time
For 5~10 minutes, it is made after finished product and carries out aging, sterilizing according to health care requirement again, disinfect.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201711426570.7A CN108117756A (en) | 2017-12-20 | 2017-12-20 | A kind of intrauterine device and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201711426570.7A CN108117756A (en) | 2017-12-20 | 2017-12-20 | A kind of intrauterine device and preparation method thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN108117756A true CN108117756A (en) | 2018-06-05 |
Family
ID=62231578
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201711426570.7A Pending CN108117756A (en) | 2017-12-20 | 2017-12-20 | A kind of intrauterine device and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN108117756A (en) |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN86204556U (en) * | 1986-06-27 | 1987-04-15 | 上海市计划生育科学研究所 | Closed cervical cap |
| US20020161352A1 (en) * | 2001-04-25 | 2002-10-31 | Lin Chen Hai | Vaginal ring preparation and application |
| CN105997844A (en) * | 2016-05-10 | 2016-10-12 | 阿坝藏族羌族自治州畜牧科学技术研究所 | Silicone rubber slow-release drug cap for vaginal suppository and preparation method of silicone rubber slow-release drug cap |
-
2017
- 2017-12-20 CN CN201711426570.7A patent/CN108117756A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN86204556U (en) * | 1986-06-27 | 1987-04-15 | 上海市计划生育科学研究所 | Closed cervical cap |
| US20020161352A1 (en) * | 2001-04-25 | 2002-10-31 | Lin Chen Hai | Vaginal ring preparation and application |
| CN105997844A (en) * | 2016-05-10 | 2016-10-12 | 阿坝藏族羌族自治州畜牧科学技术研究所 | Silicone rubber slow-release drug cap for vaginal suppository and preparation method of silicone rubber slow-release drug cap |
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| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20180605 |
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| RJ01 | Rejection of invention patent application after publication |