CN107970524A - A kind of testing stimulus device - Google Patents
A kind of testing stimulus device Download PDFInfo
- Publication number
- CN107970524A CN107970524A CN201711249536.7A CN201711249536A CN107970524A CN 107970524 A CN107970524 A CN 107970524A CN 201711249536 A CN201711249536 A CN 201711249536A CN 107970524 A CN107970524 A CN 107970524A
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- Prior art keywords
- circuit
- stimulus device
- testing stimulus
- stimulation
- microprocessor
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
- A61N1/36125—Details of circuitry or electric components
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
- A61N1/36128—Control systems
- A61N1/36146—Control systems specified by the stimulation parameters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
- A61N1/36128—Control systems
- A61N1/36189—Control systems using modulation techniques
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/372—Arrangements in connection with the implantation of stimulators
- A61N1/37211—Means for communicating with stimulators
- A61N1/37217—Means for communicating with stimulators characterised by the communication link, e.g. acoustic or tactile
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/372—Arrangements in connection with the implantation of stimulators
- A61N1/37211—Means for communicating with stimulators
- A61N1/37235—Aspects of the external programmer
- A61N1/37241—Aspects of the external programmer providing test stimulations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/372—Arrangements in connection with the implantation of stimulators
- A61N1/37211—Means for communicating with stimulators
- A61N1/37252—Details of algorithms or data aspects of communication system, e.g. handshaking, transmitting specific data or segmenting data
- A61N1/3727—Details of algorithms or data aspects of communication system, e.g. handshaking, transmitting specific data or segmenting data characterised by the modulation technique
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- Health & Medical Sciences (AREA)
- Radiology & Medical Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Acoustics & Sound (AREA)
- Physics & Mathematics (AREA)
- Electrotherapy Devices (AREA)
Abstract
Testing stimulus device, belongs to implantation medical equipment field, is mainly used for the test of nerve electric stimulation therapy.The present invention provides the testing stimulus device that one kind possesses PPM (pulse position modulation) and Bluetooth communication.Accurately electric pulse stimulation can be exported, verification curative effect is observed suitable for DBS (lesions located in deep brain), SNM (Sacral nerve electrical stimulation), the surgical procedure testing stimulus auxiliary positioning of SCS (spinal cord stimulation trial) and observation curative effect, and interim stimulate of operating room phase for a period of time.It is characterized in that：Testing stimulus device uses integrated structure design, is mainly made of the part such as shell, button, adapter, battery, printed circuit board, shape is simply compact, easy to carry；Communicated by the bluetooth of tablet computer with it, can show and adjust the information such as the parameter of testing stimulus device on tablet computer.
Description
Technical field
The present invention relates to a kind of medical instrument, especially for doctor or patient in implantation type electric stimulation therapy surgical procedure
The in-vitro test stimulator that test and assessment use, belongs to implantation medical equipment technical field.
Background technology
At present, implantation type electric stimulation system has been widely used for the treatment of neurological disease, for example, deep brain stimulation device
(brain pacemaker), which is often used to dyskinetic disorder, the spinal stimulators such as treatment Parkinson's, can be effectively improved chronic ache
Etc..The composition of implantation type electric stimulation system generally comprises an implantable impulse generator, one or more electrodes and
Connect the extension lead of impulse generator and electrode.Wherein, impulse generator is the core of system, for producing parameter
The electric stimulation pulse of (such as amplitude, frequency, pulsewidth) adjustable specific waveforms, electric pulse are conveyed to electricity by subcutaneous extension lead
Pole, acts on goal stimulus target spot by electrode contacts and plays the neural effect of regulation and control.
By taking the implantation of brain pacemaker as an example, the surgical procedure of electric stimulation implantation can be generally described as：In implantation arteries and veins
Rush before generator, be accurately positioned first by technologies such as magnetic resonance imaging and stereotaxises, finding accurately stimulates target spot to sit
After mark, electrode is implanted into brain.This process damages very little, and since brain does not have the pain sensation, thus the patient feels are less than pain
Bitterly.And the implantation of impulse generator after this and the placement of extension lead then include several relatively invasive hands
Art operating process, such as subcutaneously beating tunnel etc. with special equipment.Before implantable pulse generator, electrode is passed through survey by doctor
Examination conducting wire is connected to testing stimulus device pulse output end mouth, carries out preliminary test, such as, allow patient to do some simple dynamic
Make, such as take cup, stretch one's arm, draw helix, degree is improved according to the impression of patient and symptom, further adjusts electrode
Position and stimulation parameter, to obtain optimal therapeutic effect.If patient symptom is controlled in test, doctor can further plant
Enter whole brain pacemaker system.Specific operation is the implantable pulse generator below the infraclavicular skin of chest, then subcutaneous
Impulse generator and electrode are connected by extension lead.This process can carry out at once, can also observed number day it is laggard
OK, for example patient may may require that and electricity is pierced before the operation of implantable pulse generator and the subcutaneous extension lead of assembling is carried out
Swash the experience that therapy carries out a period of time, thus determine that can the therapy effectively inhibit illness, and whether have side reaction, such as
Have, can receive.This test experience stage can continue several hours and be differed by 30 days.
If the impulse generator of implantation is directly used as test to use, main problem is that cost is excessive.Pulse generation
Device is disposable aseptic medical equipment, once opening its aseptic packaging, then patient needs to pay ten tens of thousands of yuan of purchase
Expense is bought, if be unsatisfied with to curative effect, forms huge waste.In addition, set pulse generator parameters need to be by external journey
Control the remote control of instrument, cause doctor and the operational inconvenience of patient, and can not intuitively read pulse generator working status
And pulse parameter.Then often volume is bigger for the Medical pulse generator being commercially available on the market, is not easy to patient's carrying, shadow
The freely activity of patient is rung, its impulse waveform exported and parameter and precision also not necessarily meet Clinical practice demand.
For these problems, a kind of in-vitro test stimulator used for test assessment of invention can not only
Accurately Parameter adjustable electric pulse is provided for test phase, and compact structure is beautiful, it is simple to operate, it is easy to carry.Electricity
Pole load impedance test function can stimulate the accuracy that target spot positions with auxiliary judgment, judge whether electrode can work normally, with
And the service life of estimation stimulator for implantation.
The content of the invention
It is an object of the invention to provide a kind of external use testing stimulus for possessing pulse position modulation PPM and Bluetooth communication
Device.Accurately electric pulse stimulation can be exported, suitable for DBS (lesions located in deep brain), SNM (Sacral nerve electrical stimulation), SCS (ridges
Marrow electro photoluminescence) surgical procedure testing stimulus auxiliary positioning and observation curative effect, and operating room phase for a period of time interim
Stimulate observation verification curative effect.It is characterised in that it includes power supply, radio communication circuit, microprocessor, stimulation circuit and interface electricity
Road, it is characterised in that further include observation circuit, protection circuit, peripheral adapter and termination member, the termination member and Wei Chu
Device connection is managed, microprocessor can be forced to be stopped.
Further, the radio communication circuit includes a bluetooth communication.
Further, the radio communication circuit includes a communication coil, programmable oscillator, amplifier and wave detector, leads to
Letter coil is connected with programmable oscillator while being connected successively with amplifier and wave detector.
Further, the peripheral adapter is 1*16 electrode tests cable or 1*4 adapters.
Further, the peripheral adapter is 1*4 adapters.
Further, the protection circuit prevents reversed circuit and circuit overcurrent protection including a battery.
Further, the stimulation circuit includes multiprogram program-controlled voltage output circuit, pulse shape control circuit, electrode
Selection circuit, charge balancing circuit and output current measuring circuit.
Further, the interface circuit includes electrostatic discharge protection circuit and cable connector interface.
Further, the observation circuit include a cable connection state observation circuit, power work condition indication circuit,
Battery compartment status monitoring circuit and abnormality alert circuit.
Further, the radio communication circuit, microprocessor, stimulation circuit, interface circuit and peripheral adapter be successively
It is connected with each other.
Brief description of the drawings
Fig. 1 is the principle of the present invention schematic diagram
Fig. 2 is the schematic diagram of telecommunication circuit of the present invention
Fig. 3 is the schematic diagram of stimulation circuit of the present invention
Fig. 4 is the schematic diagram of interface circuit of the present invention
Fig. 5 is the schematic diagram of stimulation circuit of the present invention and peripheral adapter
Fig. 6 is the schematic diagram of present invention protection circuit and observation circuit
Fig. 7 is the principle of the present invention block diagram
Embodiment
The reference numeral title of the present invention is as follows：
Telecommunication circuit 1, microprocessor 2, stimulation circuit 3, interface circuit 4, peripheral adapter 5, protection circuit 6, monitoring electricity
It is road 7, scram button 8, bluetooth communication 10, programmable oscillator 11, communication coil 12, amplifier 13, wave detector 14, more
It is program program-controlled voltages output circuit 30, pulse shape control circuit 31, electrode selecting circuit 32, charge balancing circuit 33, defeated
Go out current measurement circuit 34, ESD electrostatic discharge protection circuits 40, cable connector interface 41,1*16 electrode tests cable 50,1*4 to fit
Orchestration 51, battery prevent reversed 60, circuit overcurrent protection 61, cable connection state observation circuit 70, battery, working status indication
Circuit 72, battery compartment status monitoring circuit 71, abnormality sound prompting circuit 73.
As shown in Figure 1, whole in-vitro test stimulator includes telecommunication circuit 1, microprocessor 2, stimulation circuit 3, interface
Circuit 4, peripheral adapter 5, protection circuit 6 and observation circuit 7.Wherein telecommunication circuit 1 on the one hand wirelessly with
The terminal (mobile phone, tablet computer etc.) at family is connected, on the other hand with microprocessor 2 is wired is connected.Microprocessor 2 and stimulation circuit
3 are connected, to send relevant execute instruction to stimulation circuit.Stimulation circuit 3 is connected by interface circuit 4 with peripheral adapter 5.
In order to which testing stimulus device is monitored and is protected, protection circuit 6 and observation circuit 7 are also associated with microprocessor periphery.Separately
Outside, a scram button 8 is connected with microprocessor, which is used for patient's active emergent stopping impulse stimulation.
As shown in Fig. 2, telecommunication circuit 1 includes bluetooth communication 10 and near field PPM (pulse position modulation) communication coil
12, programmable oscillator 11, amplifier 13 and wave detector 14 are in addition further included in telecommunication circuit.Bluetooth communication 10 and microprocessor
Device is connected directly, during work, bluetooth communication 10 can by wirelessly with the terminal phase such as the mobile phone of user or tablet computer
Even, user can check the arrange parameter and test effect of testing stimulus device in the terminal such as mobile phone or tablet computer, at the same time
The parameter for adjusting testing stimulus device can also be set in terminal.PPM communication coils 12 by amplifier 13 and wave detector 14 with
Microprocessor 2 is connected, and PPM communication coils are used to send or receive PPM signal, are inputted so as to fulfill to the parameter of microprocessor 2,
Microprocessor 2 is connected by programmable oscillator 11 with communication coil 12 at the same time refers to realize that microprocessor is sent to communication coil 12
Order.
Microprocessor 2 is mainly used to receiving terminal to be believed by bluetooth communication 10 to the instruction that testing stimulus device is sent
Number, additionally it is possible to the signal of the output-controlling device output is received, the instruction and data of display is exported to control device its described,
And the function such as the output of the monitoring impulse output circuit module and monitoring host work state.
As shown in figure 3, stimulation circuit 3 includes more Program program-controlled voltages output circuits 30, pulse shape control circuit
31st, electrode selecting circuit 32, charge balancing circuit 33 and output current measuring circuit 34.
As shown in Figure 4 and shown in 5, interface circuit 4 includes ESD electrostatic discharge protection circuits 40 and cable connection interface 41, wherein,
ESD (Electro-Static discharge) electrostatic discharge protection circuit 40 is mainly used for " Electro-static Driven Comb ", prevents electrostatic to cable
Connecting interface 41 causes damage, and cable connection interface 41 is mainly used for connecting stimulation circuit and peripheral adapter 5.Periphery adaptation
Device 5 can be multi-electrode test cable, such as can be 1*16 multi-electrodes test cable 50 or the adapter of 1*4 contacts.Its
Middle 1*4 adapters are mainly used for SNM DBS operation test cables of transferring.
As shown in fig. 6, for safety, the present invention has separately designed protection circuit 6 and observation circuit 7.Wherein protect circuit 6
Prevent reversed circuit 60 and current foldback circuit 61 including battery, be all connected between battery and microprocessor.Wherein battery is prevented connecing
Circnit NOT 60 be mainly used for preventing because user's operation it is improper by battery it is reversed so as to host caused by damage, and current foldback circuit
61 are mainly used for preventing electric current is excessive under single failure to be damaged to patient.Observation circuit 7 is examined including cable connection state
Slowdown monitoring circuit 70, battery, working state indicating circuit 72, battery compartment status monitoring circuit 71, abnormality sound prompting circuit 73,
Wherein cable connection state detection circuit 70 is used to detect external cable connection status, and battery compartment observation circuit 71 is used to monitor electricity
Pond lid on off state, battery, working state indicating circuit 72 are used to indicate the information such as stimulator working status and battery capacity, different
Normal state sound prompting circuit 73 is used to, when stimulator occurs abnormal, carry out sound prompting.
The above is only the preferred embodiment of the present invention, it is noted that for the ordinary skill people of the art
For member, various improvements and modifications may be made without departing from the principle of the present invention, these improvements and modifications also should
It is considered as protection scope of the present invention.In addition, although used some specific terms in this specification, but these terms are only
For convenience of explanation, do not limit the present invention in any way.
Claims (10)
1. a kind of testing stimulus device, including power supply, radio communication circuit, microprocessor, stimulation circuit and interface circuit, its feature
It is that further include observation circuit, protection circuit, peripheral adapter and termination member, the termination member is connected with microprocessor,
Microprocessor can be forced to be stopped.
2. testing stimulus device according to claim 1, it is characterised in that the radio communication circuit includes a Bluetooth communication
Module.
3. testing stimulus device according to claim 1 or 2, it is characterised in that the radio communication circuit includes a communication
Coil, programmable oscillator, amplifier and wave detector, communication coil be connected with programmable oscillator while successively with amplifier and
Wave detector is connected.
4. testing stimulus device according to claim 1, it is characterised in that the peripheral adapter is 1*16 electrode tests electricity
Cable or 1*4 adapters.
5. testing stimulus device according to claim 1, it is characterised in that the peripheral adapter is 1*4 adapters.
6. testing stimulus device according to claim 1, it is characterised in that the protection circuit prevents reversed electricity including a battery
Road and circuit overcurrent protection.
7. testing stimulus device according to claim 1, it is characterised in that the stimulation circuit includes multiprogram program-controlled voltage
Output circuit, pulse shape control circuit, electrode selecting circuit, charge balancing circuit and output current measuring circuit.
8. testing stimulus device according to claim 1, it is characterised in that the interface circuit includes Electro-static Driven Comb protection electricity
Road and cable connector interface.
9. testing stimulus device according to claim 2, it is characterised in that the observation circuit includes a cable connection state
Observation circuit, power work condition indication circuit, battery compartment status monitoring circuit and abnormality alert circuit.
10. testing stimulus device according to claim 1, it is characterised in that the radio communication circuit, microprocessor, thorn
Excitation circuit, interface circuit and peripheral adapter are connected with each other successively.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201711249536.7A CN107970524A (en) | 2017-12-01 | 2017-12-01 | A kind of testing stimulus device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201711249536.7A CN107970524A (en) | 2017-12-01 | 2017-12-01 | A kind of testing stimulus device |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN107970524A true CN107970524A (en) | 2018-05-01 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201711249536.7A Pending CN107970524A (en) | 2017-12-01 | 2017-12-01 | A kind of testing stimulus device |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111537817A (en) * | 2020-05-09 | 2020-08-14 | 南京麦澜德医疗科技有限公司 | Automatic testing tool and testing method for electrode aging life |
| WO2024032814A1 (en) * | 2022-08-08 | 2024-02-15 | 江苏畅医达医疗科技有限公司 | Brain nerve electrical stimulation system with sensing function |
Citations (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1745857A (en) * | 2005-10-28 | 2006-03-15 | 清华大学 | Implant nervous electric pulse stimulus system |
| CN101648053A (en) * | 2009-09-03 | 2010-02-17 | 清华大学 | Double-channel embedded nerve stimulator |
| CN103638599A (en) * | 2013-12-25 | 2014-03-19 | 苏州景昱医疗器械有限公司 | Implanted nerve electrical stimulation control method, device and system |
| US8849385B2 (en) * | 2008-06-30 | 2014-09-30 | Medtronic, Inc. | Lead integrity testing during suspected tachyarrhythmias |
| US9248302B2 (en) * | 2013-06-17 | 2016-02-02 | Adi Mashiach | Residual signal feedback-based control of an implant |
| CN106178281A (en) * | 2016-08-19 | 2016-12-07 | 路娜 | Recovery of melituria physical therapy device |
| CN106267561A (en) * | 2014-12-31 | 2017-01-04 | 清华大学 | A kind of electric pulse stimulation is tested device and uses the test system of this device |
| CN206548994U (en) * | 2016-11-08 | 2017-10-13 | 叶向阳 | A kind of light ecological oxygen anion health apparatus easy to install |
-
2017
- 2017-12-01 CN CN201711249536.7A patent/CN107970524A/en active Pending
Patent Citations (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1745857A (en) * | 2005-10-28 | 2006-03-15 | 清华大学 | Implant nervous electric pulse stimulus system |
| US8849385B2 (en) * | 2008-06-30 | 2014-09-30 | Medtronic, Inc. | Lead integrity testing during suspected tachyarrhythmias |
| CN101648053A (en) * | 2009-09-03 | 2010-02-17 | 清华大学 | Double-channel embedded nerve stimulator |
| US9248302B2 (en) * | 2013-06-17 | 2016-02-02 | Adi Mashiach | Residual signal feedback-based control of an implant |
| CN103638599A (en) * | 2013-12-25 | 2014-03-19 | 苏州景昱医疗器械有限公司 | Implanted nerve electrical stimulation control method, device and system |
| CN106267561A (en) * | 2014-12-31 | 2017-01-04 | 清华大学 | A kind of electric pulse stimulation is tested device and uses the test system of this device |
| CN106178281A (en) * | 2016-08-19 | 2016-12-07 | 路娜 | Recovery of melituria physical therapy device |
| CN206548994U (en) * | 2016-11-08 | 2017-10-13 | 叶向阳 | A kind of light ecological oxygen anion health apparatus easy to install |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111537817A (en) * | 2020-05-09 | 2020-08-14 | 南京麦澜德医疗科技有限公司 | Automatic testing tool and testing method for electrode aging life |
| WO2024032814A1 (en) * | 2022-08-08 | 2024-02-15 | 江苏畅医达医疗科技有限公司 | Brain nerve electrical stimulation system with sensing function |
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Application publication date: 20180501 |