CN107580518A - Method and apparatus for non-thermal nail, foot and hand fungus therapy - Google Patents
Method and apparatus for non-thermal nail, foot and hand fungus therapy Download PDFInfo
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- CN107580518A CN107580518A CN201580028691.9A CN201580028691A CN107580518A CN 107580518 A CN107580518 A CN 107580518A CN 201580028691 A CN201580028691 A CN 201580028691A CN 107580518 A CN107580518 A CN 107580518A
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Abstract
Describe the method and apparatus for treating the infection of nail or nail matrix and adjacent tissue by non-thermal type.Light irradiation region in the near infrared region of the device electromagnetic spectrum.Preferably, by using with from about 870nm to the light of about 930nm wavelength.In addition, the device includes the light emitting diode for being capable of emitting ultraviolet light.These light using the user of the device it is intended that provide gnotobasis.
Description
Priority request
This application claims the S. Utility application submitted on May 29th, 2015 No. 14/725,622 and 2014
The priority of the U.S. Provisional Patent Application submitted May 29 the 62/004th, 423, the content of the two applications pass through reference
Mode is completely integrated in this article.
Technical field
The present invention and its embodiment field be related to for by nonthermal mechanism will the region be exposed to certain wave
Long light treats the method and apparatus of the fungal infection of nail, nail matrix and adjacent tissue up to the period extended.Especially, shine
Light is penetrated by the near infrared region (NIR) from electromagnetic spectrum and the light in ultraviolet (UV) region from electromagnetic spectrum.
Background technology
The nail of many animals including humans is the excellent portion that parasite, fungi and other organisms are flourished
Position.Nail provides the excellent position of these organism survivals, because due to being removed from these regions involved by the organism
To difficulty and pain and cause these organisms to be difficult to remove.In above-mentioned organism, the fungi of many types is in these rings
Especially grown vigorously in border.A kind of such fungi is Trichophyton rubrum (Trichophyton rubrum)
The most common reason of the foot of (" T.rubrum ") --- sportsman, jock itch and tinea.
In addition, T.rubrum is due to i.e. a kind of chronic disease of onychomycosis caused by the infection of the nail and nail matrix of people
The reason for approximation 80% of case.Onychomycosis is the fungal infection of toenail or nail, and it can relate to any of nail unit
Component, including matrix, bed or plate.Onychomycosis can cause pain on nail and nail matrix, not accommodate damage.In addition, it may
Produce serious body and occupation limits, and reduce quality of life.In extreme circumstances, for example, diabetic infection,
Onychomycosis can cause the forfeiture of finger.
At present, the prevalence for onychomycosis has a various estimations, but in the Western countries, has quoted up to 18% adult
The infection rate of crowd.For the people of more than 60 years old, the prevalence rate quilt of illness rate 30%, and the onychomycosis of diabetic
Think even more high.Because these diseases still have impact on a big chunk of world population, logic is pointed out, even if using modern
Technology, nail fungi therapy field still leave some room for improvement.
A kind of method for treating nail fungi is to use topical agent.In onychomycosis and other nails and nail bed infection
In whole history, many people have shown that the such treatment of preference.These technologies have some positive onychomycosis really
Influence；But the impermeable hyperkeratosis nail plate of topical agent, this prevents them from severe infections are completely eliminated.Use
Loss of finger-nail is more successful than single topical ointment with the treatment that local treatment is combined, but this method is probably time-consuming
, temporary disability and pain.Ciclopirox (Ciclopirox) (Penlac) is the example of local application's agent, and it is as liquid
Body is applied on nail as paint, for treating as caused by Trichophyton rubrum slightly to moderate onychomycosis without regard to first
Lunule.Although safe, and relatively inexpensive, Ciclopirox treatment is seldom effective.Newer topical agent includes TerbinafineItraconazoleAnd FluconazoleTerbinafine and curative effective of Itraconazole in curing
It is widely accepted, and Fluconazole is commercially approved rapidly as local and oral drugs.
These novel drugs have the feature for strengthening its validity：Nail and nail matrix are readily penetrated through, after stopping the treatment the several months
Nail persistently be present and generally there is good security.Although published research shows the good effects of these treatments,
When the oral form of these medicaments during particularly as used for treatment onychomycosis, the length for the treatment of are equal to nail growth and go out required
Between, it typically is 4-9 months.In addition, the related side effects of these novel drugs make them not have very much many potential users
Attraction.
These medical compounds play its effect by suppressing and stopping the growth of pathomycete organism.Although the party
Method also has proved to be effective, but it is poisonous to absorb the verified liver for user of these medical compounds, and
And frequently result in the expensive and heavy monitoring to the blood chemistry of patient.
For treating the current system of this nail fungi usually using 3R classes or 4R class laser.A kind of such laser
It is Nd：YAG laser, it produces the laser pulse of short pulse in 1064nm.The outburst of these light improves the temperature of hypha,hyphae,
Pass through selective absorbing, the Main Patterns of the nutrient growth of fungi.If the temperature of 65 DEG C (149 °F) is kept for 7 seconds, this is enough to make
The protein denaturation of fungi simultaneously causes permanent lesion to fungi.Light absorbs are selective, it means that the first during treatment
The temperature of bed is no more than 45 DEG C (113 °F), and health tissues is not caused damage.These systems in terms of fungi is removed very
Effectively, however, they often cause pain to the acceptor for the treatment of.This pain is to absorb major part by the body for the acceptor treated
Caused by the light of laser, temperature rise is caused to cause pain.It means that whenever patient want by laser ablation they
Nail fungi when, they will have to undergo great pain.
Therefore, it is necessary to which a kind of method and apparatus for being used to effectively treat nail fungi, it does not cause the pain of user, not made
User will not cause user to cause any improperly expense by any potential hazard.
Got along with terms of using the antifungal therapy of low level laser (" LLLT ").Such device
Attraction is the inherent safety of near-infrared wavelength and low energy level and the lower temperature therefore used in the treatment.This
Outside, it is different from photodynamic therapy (PDT), it is not necessary to sensitising agent.PDT is proposed as the possible of onychomycosis by many people
Treatment, but it is a great challenge sensitising agent is entered nail matrix by nail.Light damage using LLLT to hypha,hyphae
Process is extremely complex process and is not exclusively understood, and its use is supported in spite of clinical evidence.The 1999 of Neuman
In the research in year, it is found that two at 870nm and 930nm peak values cause significant light injury to Escherichia coli, referring to
Neuman et al., Characterization of Photodamage to Escherichia coli in Optical
Traps, Biophysical Journal in November, 77,1999.
From that time, the most significant development in the field be by Nomir Technologies, Incorporated productions
Noveon lasers.Noveon is a kind of laser diode system, and it is operated under two wavelength (870nm and 930nm), and this two
Individual wavelength, which has shown that, confirms antimycotic property.Several researchs have been carried out, it is most important that carried out by Landsman
Research.There, the research of 180 day of these wavelength to the effect for the treatment of onychomycosis.Referring to Landsman et al.,
Treatment of Mild,Moderate,and Severe Onychomycosis Using 870-and930nm Light
Exposure (treats slight, moderate and serious onychomycosis) using the exposure of 870- and 930-nm light, Journal of the
American Podiatric Medical Association, 100 (3), in May, 2010/June.Subsequent 270 are also carried out
Its follow-up.These researchs show that the selectivity of these wavelength only has a negative impact to fungi and bacterium, without to mammal
Cell has a negative impact.Claimed embodiment is related to using these phenomenons to provide safe and efficient treatment
The method and apparatus of the mode of onychomycosis.
Correlation technique is looked back：
U.S. Patent Application Publication No. 2012/0283622 is related to the treating skin disease for being primarily suitable for treating nail fungi
Device.The use of photochemical activity material is this publication disclose, by using there is no the wavelength of booster action to patient health
Light irradiation efficiently controls fungi.Gas-discharge lamp or light emitting diode can be used as method claimed and dress
The appropriate light source put.Preferably, using the transparent shoe-shaped optics shielding housing for absorbing short wavelength light.
U.S. Patent number 7,306,620 is related to be occurred on the skin and nail of people or just in people for preventing and treating
Skin and nail below microorganism infection method.Treatment includes irradiating skin and fingernail region sufficiently long time to kill
The dead organism for causing infection.In addition, some optional features add the security for the treatment of.These options are by shielding non-sense
Dye region is from radiating and preventing caused by observing electromagnetic radiation inpairment of vision including lid to realize this point.
U.S. Patent Application Publication No. 2005/0256552 is related to a kind of battery powered toe fungi eradicator, and it can be
Cosily wear during sleep.Alternately, the device can continuously be worn.
U.S. Patent number 5,616,140 is related to the method and apparatus for therapeutic laser therapy.The device includes having
Portable, the battery-driven laser bandage of multiple super red light emitting diodes.The laser bandage can be worn and be applied by patient
It is added to specific area for treatment.Patient can dress the device up to one week before their prescriber is accessed.Providing
Treatment length at the end of, if it is desired, doctor can be different therapeutic schemes reprogram device.Alternately, doctor
Battery that can be to be included in alternative, and continue it is described as defined in therapeutic scheme.Disclosed device is small enough to can be with
It is through below clothes, so as to the normal activity without interference with patient.
International application WO2003/077996 is related to by using luminous containers to handle according to disclosed in Patent Cooperation Treaty
The apparatus and method in body exterior face.The device includes being attached on the specific outer surface of human or animal's body part or neighbouring people
Or the paster or bandage of the specific outer surface of animal body parts.Then the device delivers varying strength, wavelength, duration
Light.It is intended to treat fungi exposed to the light of this change, and it is other.
According to the prior art general view present invention：
Technology described above does not solve all problems solved by the invention.Claimed invention includes power supply,
The light emitting diode of at least one light between about 800nm and 980nm that can produce wavelength, configurable printable circuit
Plate, and the chamber with finger receiving area.Research shows, with having or the light of about 870nm and about 930nm wavelength floods
Do not have area for treatment to provide enough treatment means.Optionally, chamber can be equipped with interchangeable bottom plate and can producing purple
At least one additional source of light of outer light.
The invention provides more completely expose area for treatment and adjacent tissue with NIR light than previously expected.The present invention
Use the two kinds of light emitting diodes that can produce NIR and ultraviolet light.Other equipment does not include the two features in the prior art.
The combination of these features allows multiple users to use identical device soon after one another, without damaging the security of patient simultaneously
And the sanitary condition in the chamber of the present invention is kept simultaneously.
When compared with other devices with same nature, user's finger can be received by being included the invention provides one kind
Region chamber, it is allowed to region to be treated be completely exposed to by light emitting diode matrix and UV LED transmitting
Treatment light.For example, if user wants treatment T.rubrum infection, the foot in sporter most commonly occurs for fungi
Portion, then user foot can be placed on the present invention finger receiving area in.Then, the foot of the user will be exposed to
From scope from about 840nm to the light of about 980nm light emitting diode matrix and for mainly being carried out between treatment to device
The ultraviolet dosage of sterilization, about most preferably 383nm.The research of Tokushima Japan university shows the sky in 365nm and 385nm wavelength
Sterilization effect in gas and water.This exposure will cause to kill fungi and feel any heat or uncomfortable without using family.User does not have
It is the improvement to producing the prior art of excessive heat in user to undergo the fact that uncomfortable.
Distinguish the configuration that another feature of the invention is light emitting diode.In preferred embodiments, light emitting diode
The array being arranged on the top of chamber, and insertion will be inserted in the post between user's finger.Post is adjustable, is made
Obtaining the distance between these posts can be suitably configured to most preferably treat the finger of user.When adjustment column, light-emitting diodes
Pipe should be able to irradiate the area for treatment of user completely.These are adjustable segmented column and prior art are dramatically different.
Therefore, the present invention solves multiple problems that other devices in this area do not solve and the therefore present invention
It is novel and unique for this area.
Summary of the invention
Claimed invention is the method for treating and preventing fungal infection nail or nail matrix by non-thermal type
And device.The device includes：Power supply；At least one light emitting diode, it is operably connected with the power supply；Chamber, it has
There are inner surface, outer surface and finger receiving area, wherein the finger receiving area is optionally included in the band line on its bottom surface
The grid in hole.Light of the light emitting diode launch wavelength in the range of about 840nm and about 980nm subring sections, and at least one
The individual light emitting diode is attached to the inner surface of chamber, irradiates finger reception area as needed in the light emitting diode is allowed
The orientation in domain.Optionally, about 870nm and about 930nm wavelength will be launched.The device, which can also be optionally configured as having, to be included
The with gemel top of chamber roof.
In addition, the method for prevention from suffering from the diseases and treatment, including：At least one finger is placed in chamber first, its
Described in chamber there is inner surface, outer surface and finger receiving area, wherein the chamber has at least two light emitting diodes,
Wherein described second light emitting diode can produce the light that wavelength is about 383nm, be attached on the inner surface of the chamber, wherein
The finger receiving area has top surface and bottom surface；Then the light emitting diode is powered and to produce about 870nm peace treaties
The light of 930nm wavelength；Then finger is allowed to keep in the chamber up to the first scheduled volume time；And finally repeat the above steps
Up to the scheduled volume time.
Moreover, claimed invention contemplates the scheme of being implemented as follows, wherein sterilizing unit includes：Power supply；It is at least one
Light emitting diode, it is operably connected with the power supply, wherein the light emitting diode launch wavelength is in about 870nm and about
Light between 930nm；Spine, it has front end and distal end；Multiple fingers, it has top surface and bottom surface and front end
And distal end, wherein the distal end of finger is attached on the spine by hinge, the attachment of wherein at least one light emitting diode
Onto the finger；And chamber, it has top surface and bottom surface and finger receiving area, wherein the finger receiving area
With at least bottom surface, wherein at least one light emitting diode is attached on the inner surface of the chamber, in permission described luminous two
Pole pipe irradiates the orientation of finger receiving area as needed.
During treatment, it is possible to which unit is by fungal contamination and so if unit shares with other people, then between user
Generation cross-infection, and/or user may inadvertently pollute the finger that prior treatment is crossed again.Have confirmed, use two ripples
The treatment of long combination has inhibition to targeted fungal, and this will indicate that, stays any residual in a device true after the treatment
Bacterium will be impacted due to the secondary operation treatment cycle (' cleaning ' cycle) in the case of in the absence of user's finger.
An object of the present invention is to provide the therapeutic system for allowing fungi of the treatment on the nail or nail matrix of user.
An object of the present invention is to provide the therapeutic system for allowing fungi of the treatment on user's finger.
An object of the present invention is to provide the therapeutic system for allowing that fungi is removed from the footwear of user.
An object of the present invention, which is to provide, allows fungi of the treatment on the finger of user without causing to user
The point of user's pain produces the therapeutic system of overheat.
An object of the present invention is to provide the fungi for allowing treatment on user's finger while can adjust and to be somebody's turn to do
Device is for the optimised therapeutic system of specific user.
An object of the present invention is to provide also is sterilized to chamber using ultraviolet light-emitting diode between users
Therapeutic system.
An object of the present invention is to provide a kind of method using above-mentioned therapeutic system.
Brief description of the drawings
Fig. 1 is the front perspective view of an embodiment of the device of claimed invention.
Fig. 2 is the right parallax stereogram of the embodiment of the device of claimed invention.
Fig. 3 is the embodiment of the device of claimed invention in the case where with gemel lid is in an open position
Front perspective view.
Fig. 4 is bowing for the section of the embodiment of the device of the claimed invention of the electrical components inside of the prominent device
View.
Fig. 5 is the front view of the embodiment of the device of invention claimed while human user uses.
The flow chart for the step of Fig. 6 is the embodiment for the method for showing claimed invention.
Fig. 7 is the top view of the another embodiment of claimed invention.
Fig. 8 is to show how embodiment twists and warps and allow bowing for embodiment of the present invention of the footwear sterilization to user
View.
Fig. 9 is the top view for the heel of footwear to be exposed to the another embodiment of near-infrared and UV light.
Figure 10 is the side view of the full extension embodiment of claimed invention.
Figure 11 is the side view of the embodiment of the claimed invention in compression position.
Figure 12 A are arranged to receive the plane of the another embodiment of the present invention of left orientation finger or one group of finger
Figure.
Figure 12 B are arranged to receive the placed in the middle or another embodiment of the present invention of central orientation with respect finger or one group of finger
Plan.
Figure 12 C are arranged to receive the plane of the another embodiment of the present invention of right orientation finger or one group of finger
Figure.
Figure 13 A are the top views of embodiment of the present invention.
Figure 13 B are the rearviews of embodiment of the present invention.
Figure 13 C are the front views of embodiment of the present invention.
Figure 13 D are the side views of embodiment of the present invention.
Figure 14 is the front view that lid lifts and removed from the remainder of device theme.
Figure 15 A are the side views of the embodiment of finger escapement.
Figure 15 B are the top views of the embodiment of finger escapement.
Detailed description of the invention
Illustrate the preferred embodiment of the present invention referring now to accompanying drawing.Identical element is by identical in the various figures
Reference identifies.
Now with detailed reference to each embodiment of the present invention.These embodiments are by way of illustrating the present invention
Come what is provided, the present invention is not limited to these.In fact, those of ordinary skill in the art are reading this specification and reading
It can be appreciated that various modifications and variations can be made to it after this teaching.
Fig. 1 shows the general layout of an embodiment of claimed invention.Device 100 have inner surface 140,
Outer surface 135, and be operably connected with power supply 110.The device includes irradiation chamber 105.In this embodiment, irradiate
The top of chamber 105 is made up of with gemel lid 130.With gemel lid 130 can be lifted up and allow to device 100
Repaired and adjustable column 115.Power supply 110 and other light emitting diode operations caused in post 115.
The embodiment that Fig. 2 shows the claimed invention shown in Fig. 1, status led 155 are attached to outer
On surface 135.These status leds 155 can at least indicate that the device is power-up, in cleaning cycle, treatment week
Phase, still it is for preparing treatments for.Can be based on the inclined of given manufacturer by the specific instruction given by status led 155
It is good to configure.
Fig. 3 shows another view of embodiment of the present invention.In this embodiment, at gemel top 130
In open position, the inside of exposure irradiation chamber 105.This view show that for light emitting diode 175 and power supply 110 can be grasped
Make the line 180 connected.Pay attention to, although the embodiment connects the power supply 100 of post 115 via line 180, there may be other
Embodiment：The electrical system wireless connection of post 115 and device 100.The entity also shows finger receiving area 145 and bag
Include the grid 120 with pit of the bottom of finger receiving area 145.Interchangeable panels 150 are can also be seen that from the angle.It is interchangeable
Plate includes the whole bottom of irradiation chamber 105.The plate can swap out after user has been completed treatment cycle.This can have
Help the sterilization process of device 100 or contribute to the replacing of interchangeable panels 150 damaged.
In preferred embodiments, light emitting diode 175 includes paired light emitting diode, and peak wavelength is about
870nm and about 930nm, visual angle are ± 10 °, and for each wavelength, mean power is respectively about 50mW and about 35mW, and peak power is divided
It is not about 500mW and about 350mW.Normally lasting operating current for these devices is approximate 100mA, and the electric current conveys
Mean power exports.In order to realize that peak power exports, it is necessary to electric current is overdrived to 10 times persistently horizontal of approximation, it will
It is about 1.0A peak value.In order to be maintained in the ESD protection area of device, the peak point current only can be in 100 μ s maximum
Maintained in pulse width, and must not exceed the average power dissipation of the device.In this embodiment, energy consumption is being considered
After the average-size of finger scattered and to be treated, the diameter of light emitting diode should be approximately 5.0mm, and light emitting diode should
It is positioned to the about 25.4mm of the surface away from finger to be treated.
In another preferred embodiment, the array of light emitting diode 175 should be about 120mm and multiplies about 34.5mm.The battle array
Row have easily formed six light emitting diodes 175 of 20 rows and may more useful be six luminous two of ten duplicate rows
Pole pipe 175.Although not shown clearly in Fig. 3, the device 100 can have the light emitting diode 175 that can launch UV light,
They can be incorporated in light emitting diode matrix 175.
Fig. 4 shows the composition of one embodiment of the invention.This is to show power supply 110, the portion of transformer 160
The embodiment divided.In addition, Fig. 6 shows two printable circuit boards 165 and 170.These printable circuit boards 165 and 170
Allow user control 100.Printable circuit board 165 and 170 can be configured to include to store on how to hold
The memory and processor of the information in row predetermined treatment cycle.For example, if user will receive under about 870nm and about 930nm
Irradiation 10 minutes two cycles, then the memory and processor will include the step performed needed for the cycle.This will allow
User only presses next button to start their defined treatment cycle.
In preferred embodiments, can print circuit board includes power panel and timer plate.This will allow to be claimed
Invention device after the scheduled volume time automatic power down.Power panel will be provided for the 12V DC after the regulation of control circuit
The DC voltage of voltage and the unadjusted 42V for being powered to light emitting diode chain, the DC voltage of the 42V will be as before
It is shown to be adjusted using constant-current source.In addition, there will be single timer plate to provide countdown timer and the arteries and veins in 100 μ s
Rush being switched on and off for light emitting diode chain under width and approximate 615Hz frequency.Utilize the system, light emitting diode 175
Electric current can be set using analog voltage, and the analog voltage can be strobed and be closed to carry out pulse regulation.Total direct current
Power supply will no longer be required to strict voltage-regulation, reduce complexity and cost, because electric current is by the control electricity of each chain bottom
Road is set to constant level, as shown below.
In yet another preferred embodiment, transformer 160 has double armature windings, and allow transformer 160 by
It is configured for 115V inputs (USA) and 230V inputs (Europe).Herein, the first printed circuit board (PCB) 165 and the second printed circuit
Plate 175 has identical footprint and stacked on top of each other.In another embodiment, the control for light emitting diode 175
Printed circuit board (PCB) be attached to the bottom side of with gemel lid 130, there is double hinge to arrange and make it possible to fully beat for this
Open and be flat on the back segment of top cover, enabling completely close to area for treatment.
In yet another embodiment, the with gemel lid for area for treatment interlocks with microswitch, and this placed this
Device operates while lid is opened.In addition to the possibility of UV exposures, the emitting substance from NIR light emitting diodes 175
Outside visible spectrum, but the crystalline lens of eyes will launch the wavelength and by the wavelength focus to retina, and this will cause
Damage.Because this is outside the response of eyes, iris to the intensity of light output without response, and therefore without blink response, because
This needs prevents from operating in this condition.
Fig. 5 shows the expression of present invention while using.Light emitting diode 175 and post 115 are launching at least one
The light of predetermined wavelength.These light emitting diodes 175 and post 115 can launch wavelength from about 350nm to about 1000nm light.Excellent
In the embodiment of choosing, light emitting diode 175 and post 115 launch about 383nm, about 870nm and about 930nm light.In multiple hairs
Different light emitting diodes in optical diode 175 can be optimized to launch the light of different wave length.Post 115 can be conditioned and
Correctly holding and the finger 185 comprising user.Pay attention to, prediction post 115 will provide the exposure for more fully treating region, and this will
Realize the treatment faster, more sane of onychomycosis.In preferred embodiments, light emitting diode 175 is that have directly
Footpath 5mm two through hole pattern.In another preferred embodiment, post 115 is made up of a diameter of 8mm cylindrical body.Therefore, such as
Fruit uses the stainless steel pin of 2mm diameters in the substrate of post 115, then the grid 120 with pit can be used in locating dowel 116 and keep
These posts are vertical.The arrangement will provide the complete irradiation in space between the toenail of user and finger.
Fig. 6 shows the step of one of embodiment of method of device of requirement protection.This method is with step
1100 start, and wherein at least one in their finger is placed into the device of claimed invention by user.
In step 1200, the device is powered.Step 1300 includes：The problem of being possible to the result of fork.
Step 1300 considers whether the device of claimed invention includes memory and processor.If it is, require
The device of the invention of protection will start the content that performs in its memory and proceed to step 1400.If NO, then it is disclosed
The embodiment of method requires that user controls light emitting diode and post to meet defined treatment procedure manually.
In step 1400, light emitting diode and post shine at least with the light that wavelength is about 383nm, 870nm and 930nm
Penetrate irradiation chamber.
In step 1500, processor checks memory to check predetermined treatment program whether with ultraviolet light used by order
The finger at family.In preferred embodiments, the light has about 383nm wavelength.If predetermined treatment program certain claim shines
The finger of user is penetrated, then step 1550 will be performed and finger will be illuminated.
If established procedure does not require ultraviolet light, this method proceeds to step 1600.There, this method inspection is deposited
Reservoir is to judge whether treatment cycle needs to repeat.Make a reservation for if it is, light emitting diode and post will turn off in step 1650
The time of amount, then proceed by and return to step 1400.If treatment cycle does not repeat, the embodiment proceeds to step
1700。
In step 1700, the finger of user will remove from irradiation chamber, and then this method determines whether to start clearly
The clean cycle.If it is, the embodiment proceeds to step 1750 and starts cleaning cycle.If NO, then this method is carried out
To step 1800, and the device power down.In an embodiment of this method, treatment cycle will continue 15 minutes.
Fig. 7 and Fig. 8 is shown by special optimization with by removing any fungi from the footwear of the user come the footwear to user
The embodiment of the device of sterilization.It is worth noting that, the mechanism of light emitting diode 175 and requirement described before this are protected
The embodiment of the device of the invention of shield is identical.Important difference is, is not light emitting diode in sterilizing unit 200
175 are in static array, and light emitting diode 175 is located on the finger 215 for the embodiment extended from spine 190.
In another preferred embodiment, each finger 215 by being formed with the printed circuit board (PCB) of resin canning, 90 ° of torsion spring around
Pivoting point, spine 190 assign the stop position perpendicular to central spine part.The mechanism causes finger to can extend to footwear
Outer boundary, as depicted in fig. 8.
In each finger, six (3 pairs) NIR light emitting diodes 175 be present, they above and below, and
Between each pair, a UV light emitting diode 175 for being installed to center be present.Upper light emitting diode and lower light emitting diode need
Staggeredly to allow them to be installed on printed circuit board (PCB).In order to adapt to the shape of typical footwear, there is preferably at least
The finger 215 of three different lengths, in the either side mirror image of central spine part 190.Utilize footwear illuminated in this way
Anterior or foot 225, the rear heel 220 of footwear will also need to expose.
In the figure 7, the finger 215 in the rear heel 220 of sterilizing unit 200 be present.Two shown construction cards
Real finger 215 can be arranged fully illuminates covering so as to provide to article of footwear.Two constructions are intended to illustrate
Possible construction, it would be recognized by those skilled in the art that multiple modified examples of the arrangement of finger 215 be present.
In the presence of using the multiple fingers 215 " being fanned out to " in rear heel 220 around the torsion spring of pivoting point.In addition, finger-type
Part 215 can point to rear heel 220 from rear heel 220 and foot 225, so as to which provide rear heel 220 illuminates covering.Such as Fig. 8
Shown finger 215 can be arranged to provide and article of footwear is completely covered, or can be only present on foot 225.
If existed only on foot 225, sterilizing unit can be further using the saddle illuminated (see Fig. 9).However, as described by
Saddle can be also used in combination with the finger in rear heel 220.
Referring now to Figure 9, the saddle element of the particular in the presence of the device, it is intended to the heel to user's footwear
Cleaned and sterilized in portion.Such as finger 215 (referring to Fig. 8), saddle is housed in the printable circuit board of resin canning
In shape structure.The printable circuit board is installed on spring-loaded axle so that it to be kept relative to the rear portion of footwear.
Figure 10 and Figure 11 shows the operation of the axis of centres 195.The axis of centres 195 provides two kinds of functions：The tune of finger
Section, and the support and positioning of heel plate.In one embodiment, in order to adapt to make finger closely be embedded in spine 190
Needed for movement, the axis of centres 195 needs to move forward approximate 5mm.
For the embodiment shown in Figure 10 and Figure 11, finger is arranged between two thin steel plates.Two fingers
In the finger of lower section slightly extend in front end and the preceding backstop of the device be provided.Two vertical plates set dress front and rear
The height put and allow the positioning of the axis of centres 195.Upper plate has 90 ° of bendings and serves as guarantor when device is compressed for and removed
Hold a little.In order to adapt to required regulation, two compression springs will be preferably needed.It is vertical after distance piece and spring guiding docking
Plate, the snap ring on the rear portion of the axis of centres 195 prevent heel plate from being separated under spring pressure.Heel plate 210 can be in the axis of centres
Forward slip and by compression spring on 195, this will keep heel plate 210 against the rear portion of footwear.At this stage, the axis of centres 195 will
On the position of the finger 215 in footwear without influence, the finger 215 in footwear is by the position of themselves.
When the device is removed, heel plate 210 is pushed away and second on the axis of centres 195 will be promoted to block further along
Ring.The axis of centres 195 is pushed away forward and finger is changed angle and into spine 190 so as to easy removal by this.
Figure 12 A-C demonstrate another possible embodiment of the present invention.Show with gemel and/or removable
Lid 130 device 100 embodiment plan, the with gemel and/or removable lid 130 is by least two
Support column 270 is supported and coupled via male connector 240 with the compatible female connector being preferably located on apparatus main body.Covering
The bottom side of son 130 is the multiple LED 175 arranged with array 275.Multiple LED 175 preferably with operating wave described before
It is long consistent, however, the combination of other wavelength or wavelength can be conceived.Array 275 is by rotatable bar 250 along at least one transverse direction
Side, preferably two sides are tied, and this enables array 275 to be used as an integral-rotation, so that LED is overall along solid
Determine path rotation.Further, it is embedded and/or prominent therefrom multiple UV LED 230 along the bottom side of lid 130.UV
LED 230 does not form the part of array 275 preferably and can be not present in some embodiments.
On the outer surface of lid 130, the dial 220 coupled via Rotatable mechanism 260 with array 275 be present.Mark
Scale 220 be configured to each in such as Figure 12 A, Figure 12 B and Figure 12 C shown at least three diverse locations between freely
Ground rotates.When, upon rotating, dial plate 220 causes the rotation of Rotatable mechanism 260, this so that cause the arrangement of array 275 or take
To as integral-rotation.
The rotation of array 275 provides multiple advantages.For example, by operating dial 220, can be by array 275 with using
The special angle that the foot at family or other appendages are formed more closely aligns.This cause fully covering left foot portion and right foot it is complete
Portion's toe head.Therefore, user may expect to treat their left foot portion (referring to Figure 12 A), then by array 275 be orientated with treatment he
Right foot (referring to Figure 12 C).Each orientation ensures that whole toe heads receive the overlapping treatment of light and without appendage or toe head
Inserted with clumsy or uncomfortable angle.In other more neutral arrangements that may relate to hand or single finger, the possible phase
Hope center or neutral position (referring to Figure 12 B).If not possessing makes array 275 orient and adapt to the flexible of their appendage angle
Property, then appendage itself have to may be uncomfortable angular orientation and further can be constrained by the construction of device in itself.
With reference now to Figure 13 A-D, the different views of embodiment of the present invention be present.The view from top (Figure 13 A),
Front (Figure 13 C), sidepiece (Figure 13 D) and rear (Figure 13 B) show device 100.
In figure 13a, the top view of device be present.The top view of device has dial 260, and the dial to house
Lamp array row 275 in the bottom side of lid 130 can rotate.Lid 130 is propped up by remaining apparatus structure and support column 170
Support.Support column 170 has coupling mechanism 345, and such as high intensity (for example, Neodymium) magnet is with while device uses
Ensure the position of lid 130.
Lamp array row 275 are rotatably coupled with lid 130.Dial 260 causes lamp array row to be directed to and meet use
The desired orientation in family.Bottom side or therefrom prominent multiple UV LEDs 230 of the side of array 275 with embedded lid surface
Connect.On the contrary, lamp array row 275 have the lamp of transmitting those consistent wavelength as previously described.In some cases, it is as follows
Text further illustrates that lid 130 can be removed to allow for that there are different groups of LED different arrays to be coupled with apparatus main body.
Finger (multiple) or appendage is allowed to be freely inserted finger/appendage, it can be seen that support column 170 defines from above
" the open concept " of receiving area 145.The nonrestrictive open orientation for allowing user to adjust their finger/appendage, together
When additionally provide enough air-flows come any afterheat caused by LED that helps to dissipate.In addition, shown out from the side in Figure 13 D
The concept put.Therefore, finger receiving area 145 is substantially open, along three sides of the device, even for support column
170.Remaining enclosed edge is preferably the rear side of device.
Also as illustrated in figure 13d be state LED 155.In the presence of as described herein or being otherwise contained in this hair
Any number of mode of operation in bright scope.For example, the state LED shown in Figure 13 D corresponds to " RUN " cycle, " cleaning "
Cycle, " timing " cycle and " frequency " cycle.On device in use shown cycle or setting can with accompanying drawing
This reflects identical or different.
The rear side of device can include power import 125 and power outlet 127.Power import 125 allows power supply 110
Connection is (referring to Fig. 2).Power outlet 127 can provide the appropriate connections of USB or other to supply electricity to finger space mechanism 360
Power, as shown in Figure 15 A-B.
In fig. 14, the lid 130 as described by Figure 13 A can be detachable.The effect of the dismountable lid 130 can
With the change and/or replacing for providing the further cleaning of device and providing part.For example, lid 130 as depicted and mother
Connector 265 couples, and female connector 265 can be the appropriate connection patterns of Molex or other.Male connector 240 fits in mother
Received in connector 265 and by female connector 265.As male female connections part is directed on appropriate location, holding pin 280
It is fastened on apparatus main body.
Holding pin 280 provides rigidity for lid 130 in use and prevents the either direction of lid 130 from reversing, so as to
Prevent damage lid 130 or connector during use, storage, transport etc..Fastening structure 280 can be constructed to be fitted to by
The dowels such as stainless steel or other metals, plastics, rubber in device 285.Each retention mechanism 280 is designed to be fitted to a receiver
Multiple retention mechanisms can be located in single receiver in 285 and in some embodiments.
In fact, lid 130 can be removed so that array 275 can be replaced with different and similar arrays
275.For example, in order to provide the treatment to different skin type, it is beneficial to make device 100 that there are the custom features.Than more shallow
The dark skin color that skin color has higher concentration melanin will cause light absorbs to increase, so as to deleteriously influence to be applied
Treatment infiltration degree.By change lid 130 and then by array 275 be replaced with another array 275 being more suitable for
And the light of associated wavelength, correctly treatment will be realized without changing each LED.
With reference now to Figure 15 A-B, the finger that can be used together with the embodiment of invention as described herein be present
Space mechanism 360.In some instances, finger space mechanism 360 can use in the case of without device 100 itself.Refer to
Head space mechanism 360 generally has first surface 310, second surface 320, at least two distance pieces 330, and LED 175 is housed in
In distance piece 330.In addition, the electronics that the electric power in cable 350 and wiring 340 is made it possible between realization device and LED 175 leads to
Letter.
Finger space mechanism 360 can be made up of any number of material, including but not limited to plastics, rubber, foam and
Silicone or its any combination.First surface 310, second surface 320 and distance piece 330 can the identical or different material structures of each freedom
Into.For correct transmission light during being allowed in treatment (treatment is conveyed to the space between finger), it is important that selected material
Show and light is transmitted and is extended in the either side direction at least 500nm of visible spectrum good in all visible wavelengths
Good optical transparency.
Preferably, first surface 310 and second surface 320 position in a manner of on being essentially parallel to each other.Distance piece 330
Be preferably positioned as between first surface 310 and second surface 320 and with it is each in first surface 310 and second surface 320
Individual coupling.Clearance space 390 be present between each distance piece 330.Preferably, at least one and more preferably at least two LED
175 are arranged in each distance piece 330.When using two LED 175, LED launches about 870nm and about 940nm light respectively.
LED 175 is via the coupling of wiring 340, with the wiring being preferably embedded in first surface 310 or second surface 320
340 are connected in series.In addition, the electric power for the operation of finger space mechanism 360 is supplied via the electric power in cable 350.Line
Electric power in cable 350 can couple (see Fig. 2) with device or power supply 110.
Finger space mechanism 360 is intended to ambidexterity, because user can only need a mechanism, rather than two machines
Structure.When in use, finger space mechanism 360 can be adapted to along for example right foot, left foot portion, left hand or the right hand.If it is used for
Side (that is, left side) is for use in the corresponding appendage of right side of body, then mechanism must be only inverted.Therefore, when with institute in Figure 15 A
When the view shown is compared, first surface 310 will be located at bottom, and second surface 320 is located at top.In addition, the mechanism can be
Appendage is placed into before being placed into the device for treatment.
Although describe the present invention using a certain degree of particularity, it should be understood that the disclosure only passes through the side of example
Formula is made, and can take some changes on the construction of part and the details of arrangement, without departing from the present invention purport and
Scope.
Claims (28)
1. the therapeutic system for treating nail, nail matrix and surrounding tissue, the therapeutic system include：
Power supply；
At least one light emitting diode being operatively connected with the power supply,
Wherein described at least one light emitting diode launch wavelength is light of the about 870nm to about 930nm；And
Chamber, it has inner surface and outer surface, and finger receiving area,
Wherein described finger receiving area has at least bottom surface,
Wherein at least one light emitting diode is attached on the inner surface of the chamber, in permission at least one light-emitting diodes
Pipe irradiates the orientation of the finger receiving area as needed.
2. device as claimed in claim 1, in addition to：At least one additional light emitting diode, the light emitting diode can
Produce the light of about 383nm wavelength；
Wherein described light emitting diode is attached on the inner surface of the chamber, and the light emitting diode is fixed on permission institute
State orientation of the light emitting diode using the finger receiving area of chamber described in ultraviolet light.
3. device as claimed in claim 1, wherein the with gemel lid with top surface and bottom surface forms the top of chamber,
And at least one light emitting diode is connected with the bottom surface of the with gemel lid.
4. device as claimed in claim 1, in addition to：The adjustable post being operably connected with the power supply；
Wherein described post includes at least one light emitting diode, and
Wherein described post is inserted into the bottom surface of the finger receiving area and allowed them between the finger of user.
5. device as claimed in claim 1, in addition to：It is placed on the interchangeable panels of the bottom of the finger receiving area.
6. device as claimed in claim 1, wherein in the presence of at least two light emitting diodes,
Wherein described light emitting diode respectively launch wavelength be about 870nm and 930nm light.
7. device as claimed in claim 1, wherein the outer surface of the chamber includes dress of the instruction using predetermined treatment plan
The multiple light emitting diodes for the state put.
8. the therapeutic system for treating nail, nail matrix and surrounding tissue, the therapeutic system include：
Power supply；
Multiple light emitting diodes, it is operably connected with the power supply,
Wherein described light emitting diode launch wavelength is about 870nm and about 930nm light；
At least one ultraviolet lamp, it can produce the light that wavelength is about 383nm；
Chamber, it has inner surface and outer surface, and finger receiving area,
Wherein described finger receiving area has at least bottom surface,
Wherein described finger receiving area is sufficiently large to user and at least one finger is comfortably placed in the chamber；With
And
Governor motion, its space being used between adjustable column is to adapt to the different sizes of the finger of potential user.
9. device as claimed in claim 8, wherein with gemel lid forms the top of the finger receiving area, and
The multiple light emitting diode is connected with the with gemel lid.
10. device as claimed in claim 8, wherein the bottom of the finger receiving area is made up of interchangeable panels.
11. device as claimed in claim 8, wherein the post includes at least one light emitting diode and connect with described device line
Or wireless connection.
12. device as claimed in claim 10, wherein the finger that the interchangeable panels can also extend beyond the chamber connects
Receive region.
13. device as claimed in claim 8, wherein the outer surface of the chamber includes dress of the instruction using predetermined treatment plan
The multiple light emitting diodes for the state put.
14. nail and dermatophyte prevention and treatment method, including：
A) therapeutic system irradiation treatment region is used,
Wherein described therapeutic system includes,
Power supply,
The multiple light emitting diodes being operably connected with the power supply,
Light of the wherein described light emitting diode launch wavelength between about 870nm and about 930nm, and
At least one ultraviolet light-emitting diode, it can produce the light that wavelength is about 383nm；
B) area for treatment is allowed to keep being irradiated up to the first scheduled volume time by the therapeutic system；And
C) every about seven days repeat step a) to b) once up to the second scheduled volume time.
15. nail and dermatophyte prevention and treatment method, including：
A) at least one finger is placed in chamber,
Wherein described chamber has inner surface, outer surface and finger receiving area,
Wherein described chamber has at least two light emitting diodes, wherein at least one at least two light emitting diode
The light that wavelength is about 383nm can be produced and be attached to the inner surface of the chamber,
Wherein described finger receiving area has top surface and bottom surface；
B) chamber is powered and to produce light of the wavelength between about 870nm and about 930nm；
C) finger is allowed to keep in the cavity up to the first scheduled volume time；And
D) one week repeat step (a) to (c) once up to the second scheduled volume time.
16. method as claimed in claim 15, in addition to step (e),
Wherein start cleaning cycle after the treatment cycle,
Wherein described cleaning cycle reaches the scheduled volume time including the chamber described in the light irradiation that wavelength is about 383nm.
17. method as claimed in claim 15, wherein methods described consider whether described device includes processor and memory,
If it is, methods described also includes described device according to the content of the memory and automatically beginning and end
The step of predetermined treatment cycle.
18. method as claimed in claim 15, also comprises the following steps：Last five points in the first scheduled volume time
In clock, at least one light emitting diode that wavelength is about 383nm is connected.
19. sterilizing unit, including：
Power supply；
At least one light emitting diode being operably connected with the power supply,
Wherein described at least one light emitting diode launch wavelength is light of the about 870nm to about 930nm；
Spine, it has front end and distal end；
Multiple fingers, it has top surface and bottom surface and front end and distal end,
The distal end of wherein described finger is attached to the spine by hinge,
Wherein described at least one light emitting diode is attached to finger.
20. device as claimed in claim 19, in addition to the heel plate with flat front surface end and rounded distal, the heel
Plate is connected with the distal end of the spine,
Wherein described heel plate includes at least two light emitting diodes,
First light emitting diode is configured as light of the transmitting with about 870nm and about 930nm wavelength,
Second light emitting diode is configured as light of the transmitting with about 383nm wavelength,
Wherein described at least two light emitting diode is evenly spaced in the whole heel plate.
21. device as claimed in claim 20, wherein the spine is by the first and second hollow tube-shape bodies and compression spring
Form,
Wherein described first hollow tube-shape body has the diameter less than the second hollow tube-shape body and make it that described first is hollow
Cylindrical body can be placed in the second hollow tube-shape body,
Wherein described compression spring is inserted between the first hollow tube-shape body and the second hollow tube-shape body and so that two hollow
Cylindrical body is rested on extended position, but when appropriate power applies, the first and second hollow tube-shapes body will compress with
Adaptation is placed on compared with subenvironment.
22. the treatment external member of fungi is treated, including：
Therapeutic system, including,
Power supply；
At least one light emitting diode being operably connected with the power supply,
Wherein described at least one light emitting diode launch wavelength is about 870nm and about 930nm light；And
Chamber, the chamber have inner surface and outer surface, and finger receiving area,
Wherein described finger receiving area has at least bottom surface,
Wherein at least one light emitting diode is attached on the inner surface of the chamber, in permission at least one light-emitting diodes
Pipe irradiates the orientation of the finger receiving area as needed；And
Sterilizing unit, including,
Power supply,
At least one light emitting diode, it is operably connected with the power supply,
Wherein described light emitting diode launch wavelength is about 870nm and about 930nm light,
Spine, it has front end and distal end,
Multiple fingers, it has top surface and bottom surface and front end and distal end,
The distal end of wherein described finger is attached by hinge and the spine, and
Wherein described at least one light emitting diode is attached to finger.
23. treatment external member as claimed in claim 22, wherein the sterilizing unit also includes,
Heel plate, it has flat front surface end and rounded distal, is connected with the distal end of the spine,
Wherein described heel plate includes at least two light emitting diodes,
First light emitting diode is configured as light of the transmitting with about 870nm and about 930nm wavelength, and
Second light emitting diode is configured as light of the transmitting with about 383nm wavelength.
24. therapeutic system as claimed in claim 1, in addition to finger space mechanism.
25. therapeutic system as claimed in claim 24, wherein the finger space mechanism includes：
First surface and second surface, the first surface are spaced a distance with the second surface；
At least two distance pieces, its between the first surface and the second surface and with the first surface and described
Each coupling in second surface,
In wherein described at least two distance piece each have be housed at least two light source therein.
26. therapeutic system as claimed in claim 1, in addition to the dial coupled with least one light emitting diode.
27. therapeutic system as claimed in claim 26, wherein in the presence of via Rotatable mechanism and at least one dial
Multiple light emitting diodes of coupling,
The rotation of wherein described dial makes the multiple light emitting diode integral-rotation.
28. therapeutic system as claimed in claim 3, wherein the with gemel lid can be removed.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462004423P | 2014-05-29 | 2014-05-29 | |
| US62/004,423 | 2014-05-29 | ||
| PCT/US2015/033302 WO2015184336A1 (en) | 2014-05-29 | 2015-05-29 | Method and apparatus for non-thermal nail, foot, and hand fungus treatment |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN107580518A true CN107580518A (en) | 2018-01-12 |
Family
ID=61049663
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201580028691.9A Pending CN107580518A (en) | 2014-05-29 | 2015-05-29 | Method and apparatus for non-thermal nail, foot and hand fungus therapy |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN107580518A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111659029A (en) * | 2020-07-10 | 2020-09-15 | 西安交通大学医学院第一附属医院 | Domestic laser therapeutic instrument for onychomycosis |
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| US20060212098A1 (en) * | 2005-01-13 | 2006-09-21 | Constantinos Demetriou | Method and apparatus for treating a diseased nail |
| US20080058905A1 (en) * | 2006-09-01 | 2008-03-06 | Wagner Darrell O | Method and apparatus utilizing light as therapy for fungal infection |
| US20080234786A1 (en) * | 2002-02-11 | 2008-09-25 | Cumbie William E | Prevention and treatment of skin and nail infections using germicidal light |
| US20120283622A1 (en) * | 2009-11-10 | 2012-11-08 | Nath Guenther | Dermatological treatment device |
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|---|---|---|---|---|
| US20080234786A1 (en) * | 2002-02-11 | 2008-09-25 | Cumbie William E | Prevention and treatment of skin and nail infections using germicidal light |
| US20060212098A1 (en) * | 2005-01-13 | 2006-09-21 | Constantinos Demetriou | Method and apparatus for treating a diseased nail |
| US20080058905A1 (en) * | 2006-09-01 | 2008-03-06 | Wagner Darrell O | Method and apparatus utilizing light as therapy for fungal infection |
| US20120283622A1 (en) * | 2009-11-10 | 2012-11-08 | Nath Guenther | Dermatological treatment device |
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| CN111659029A (en) * | 2020-07-10 | 2020-09-15 | 西安交通大学医学院第一附属医院 | Domestic laser therapeutic instrument for onychomycosis |
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