CN107515306B - A kind of kit of CA215 and CA15-3 joint-detection patient with breast cancer - Google Patents

A kind of kit of CA215 and CA15-3 joint-detection patient with breast cancer Download PDF

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Publication number
CN107515306B
CN107515306B CN201710712573.0A CN201710712573A CN107515306B CN 107515306 B CN107515306 B CN 107515306B CN 201710712573 A CN201710712573 A CN 201710712573A CN 107515306 B CN107515306 B CN 107515306B
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box body
memotron
reagent
kit
piston body
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CN107515306A (en
Inventor
廖兴华
覃欢
项园
姚奥
范丽娟
姚凯
顾朝江
张同存
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Wuhan University of Science and Engineering WUSE
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Wuhan University of Science and Engineering WUSE
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407Specifically defined cancers
    • G01N33/57415Specifically defined cancers of breast

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Oncology (AREA)
  • Hospice & Palliative Care (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Cell Biology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

The present invention relates to technical field of medical equipment, the kit of especially a kind of CA215 and CA15-3 joint-detection patient with breast cancer, including reagent box body, reagent tray interior is equipped with several memotrons, extend the setting of reagent box portion outside at the top of each memotron, each storage bottom of the tube is equipped with air inlet pipe, reagent box body bottom is equipped with control box body, it controls tray interior side and is equipped with gas tube identical with memotron quantity, escape pipe is equipped on each gas tube, hose is respectively connected on each escape pipe, hose is both connected in air inlet pipe far from one end of escape pipe, hose is equipped with Non-return air valve, reagent box portion outside is arranged with cover, each memotron runs through cover setting;The present invention effectively improves the accuracy of CA215 and CA15-3 detection, and realize Reagent Tube facilitates pick-and-place.

Description

A kind of kit of CA215 and CA15-3 joint-detection patient with breast cancer
Technical field
The present invention relates to technical field of medical equipment more particularly to a kind of CA215 and CA15-3 joint-detection breast cancer to suffer from The kit of person.
Background technique
With the development of economy, the increase of operating pressure, the factors such as environmental pollution and diet problem, leads to cancer Sick hair rate is higher and higher, and wherein breast cancer is a kind of most common disease, and breast cancer incidence accounts for the 31% of gynecological tumor, dead Rate remains high in tumour, because tumor disease cannot be found in time, and misses optimal treatment time, diagnosed in early period Kit is essential detection instrument in journey, and the generation of kit is precisely in order to enable experimenter to get rid of heavy examination Agent preparation and optimization process are sugar antigen, were using for CA215 and CA15-3 that detection patient with breast cancer uses Cheng Zhong, it is too long to be not easy the residence time at room temperature, and the residence time is too long will to will affect detection effect, and existing kit Structure is simple, does not have the effect of low-temperature protection reagent, also, extremely inconvenient, shadow when taking using tweezers reagent out of kit Ring detection procedure.
Summary of the invention
The purpose of the present invention is to solve reagent exists in the prior art to pick and place inconvenience, do not have lacking for low-temperature protection Point, and the kit of the CA215 and CA15-3 joint-detection patient with breast cancer proposed a kind of.
To achieve the goals above, present invention employs following technical solutions:
Design the kit of a kind of CA215 and CA15-3 joint-detection patient with breast cancer, including reagent box body, the reagent Tray interior is equipped with several memotrons, extends the setting of reagent box portion outside, each storage bottom of the tube at the top of each memotron It is equipped with air inlet pipe, reagent box body bottom is equipped with control box body, and the control tray interior side is equipped with and memotron number Identical gas tube is measured, escape pipe is equipped on each gas tube, hose is respectively connected on each escape pipe, hose is far from outlet One end of pipe is both connected in air inlet pipe, and hose is equipped with Non-return air valve, and the reagent box portion outside is arranged with cover, each storage Guan Jun is deposited to be arranged through cover.
Preferably, first piston body is equipped in each memotron, first piston body lower end is equipped with exhaust Pipe, the exhaust pipe bottom end inside are equipped with annular flange, run through on the axis of the first piston body and be equipped with sliding bar, institute It states on first piston body and is located at sliding bar surrounding and be equipped with several gas vents, the top of the sliding bar is equipped with loading plate, Second spring is equipped between loading plate and first piston body, the bottom end of the sliding bar is equipped with cylinder, opens up on cylinder There is strip air discharge duct, the air discharge duct is respectively positioned on inside exhaust pipe, and the cylinder bottom end is respectively positioned in the annular flange, and Sealing ring is equipped between annular flange and cylinder.
Preferably, several gas vents are respectively positioned between the exhaust pipe and cylinder.
Preferably, the loading plate upper surface is arcuate structure, and rubber pad, the diameter of the loading plate are equipped in arc Less than the diameter of the memotron, Reagent Tube is placed on the loading plate, the Reagent Tube is located in memotron, the reagent Pipe is provided with CA215 and CA15-3 association.
Preferably, it is equipped with second piston body in each gas tube, is equipped with if running through on the second piston body Dry air vent, the side that second piston body is located at the escape pipe are equipped with pad of holding one's breath, and second piston body is far from holding one's breath the one of pad Side is rotatably connected to connecting rod, and connecting rod is respectively connected with pressing plate far from one end of second piston body, and one end of the pressing plate rotates On being connected on the outside of the control box body, the other end is respectively connected with the first spring, and the one end of the first spring far from pressing plate is fixed On the control box body outer wall.
Preferably, the pad of holding one's breath covers each air vent, and the pad of holding one's breath is in rubber or silica gel material It is a kind of.
Preferably, it is equipped with insulating layer on the inside of the cover, is equipped between the cover at the top of the reagent box body close Packing.
Preferably, ice cube is filled in the kit body.
Preferably, sealing-plug is equipped at the top of the memotron.
The kit of a kind of CA215 proposed by the present invention and CA15-3 joint-detection patient with breast cancer, beneficial effect are: The present invention makes CA215 and CA15-3 be in low-temperature condition, effectively avoids CA215 and the CA15-3 residence time under room temperature state It is too long, caused detection effect it is inaccurate and the phenomenon that, when taking CA215 and CA15-3 reagent, it is only necessary to pass through the external pressure of pressing Plate is constantly inflated for memotron so that loading plate rises from CA215 and CA15-3 Reagent Tube, thus realize CA215 with CA15-3 Reagent Tube fast and easily picks and places.
Detailed description of the invention
Fig. 1 is that a kind of structure of the kit of CA215 and CA15-3 joint-detection patient with breast cancer proposed by the present invention is shown It is intended to;
Fig. 2 is the side view knot of the kit of a kind of CA215 and CA15-3 joint-detection patient with breast cancer proposed by the present invention Structure schematic diagram;
Fig. 3 is partial enlargement structural representation at the A1-A1 of Fig. 1 of the present invention;
Fig. 4 is partial enlargement structural representation at the A2-A2 of Fig. 1 of the present invention.
In figure: reagent box body 1, control box body 2, memotron 3, Reagent Tube 4, cover 5, gas tube 6, escape pipe 7, unidirectional gas Valve 8, hose 9, air inlet pipe 10, pressing plate 11, the first spring 12, connecting rod 13, sealing-plug 14, insulating layer 15, gasket 16, ice cube 17, first piston body 18, exhaust pipe 19, sliding bar 20, loading plate 21, cylinder 22, gas vent 23, annular flange 24, air discharge duct 25, second piston body 26, air vent 27, pad 28 of holding one's breath, second spring 29.
Specific embodiment
Following will be combined with the drawings in the embodiments of the present invention, and technical solution in the embodiment of the present invention carries out clear, complete Site preparation description, it is clear that described embodiments are only a part of the embodiments of the present invention, instead of all the embodiments.
Referring to Fig.1-4, the kit of a kind of CA215 and CA15-3 joint-detection patient with breast cancer, including reagent box body 1, It is equipped with several memotrons 3 inside reagent box body 1, is equipped with sealing-plug 14 at the top of each memotron 3, sealing-plug 14 can effectively reduce 3 internal temperature of memotron is exchanged with ambient temperature, and the top of each memotron 3 is extended to be arranged outside reagent box body 1, each 3 bottom of memotron is equipped with air inlet pipe 10, and 1 bottom of reagent box body is equipped with control box body 2, control 2 interior side of box body be equipped with The identical gas tube 6 of 3 quantity of memotron is equipped with escape pipe 7 on each gas tube 6, is respectively connected with hose on each escape pipe 7 9, hose 9 is both connected in air inlet pipe 10 far from one end of escape pipe 7, and hose 9 is equipped with Non-return air valve 8, and Non-return air valve 8 are permitted Perhaps air-flow is flowed from gas tube 6 into memotron 3, and air-flow is prevented to flow from memotron 3 into gas tube 6,1 outer cover of reagent box body Equipped with cover 5, each memotron 3 is arranged through cover 5, is equipped with insulating layer 15 on the inside of cover 5, insulating layer 15 effectively reduces 1 inside of reagent box body is exchanged with extraneous heat, is equipped with gasket 16 between 1 top of reagent box body and cover 5, gasket 16 has Effect avoids the liquid leakage melted in reagent box body 1, and ice cube 17 is filled in reagent box body 1, and ice cube 17 effectively keeps memotron 3 Always it is in low-temperature condition.
First piston body 18 is equipped in each memotron 3,18 lower end of first piston body is equipped with exhaust pipe 19, exhaust pipe It is equipped with annular flange 24 on the inside of 19 bottom ends, runs through on the axis of first piston body 18 and is equipped with sliding bar 20, first piston body Several gas vents 23 are equipped on 18 and positioned at 20 surrounding of sliding bar, the top of sliding bar 20 is equipped with loading plate 21, loading plate Second spring 29 is equipped between 21 and first piston body 18, the bottom end of sliding bar 20 is equipped with cylinder 22, opens on cylinder 22 Equipped with strip air discharge duct 25, air discharge duct 25 is respectively positioned on inside exhaust pipe 19, and 22 bottom end of cylinder is respectively positioned in annular flange 24, and Sealing ring is equipped between annular flange 24 and cylinder 22, several gas vents 23 are respectively positioned between exhaust pipe 19 and cylinder 22, hold 21 upper surface of support plate is arcuate structure, and rubber pad is equipped in arc, and rubber pad effectively avoids the damage of Reagent Tube 4, loading plate 21 diameter is less than the diameter of memotron 3, between there are gap facilitate the flowing of 3 internal gas of memotron, on loading plate 21 It is placed with Reagent Tube 4, Reagent Tube 4 is located in memotron 3, and Reagent Tube 4 is provided with CA215 and CA15-3 association.
It is equipped with second piston body 26 in each gas tube 6, runs through on second piston body 26 and is equipped with several air vents 27, The side that second piston body 26 is located at escape pipe 7 is equipped with pad 28 of holding one's breath, and side of the second piston body 26 far from pad 28 of holding one's breath is equal It is rotatably connected to connecting rod 13, connecting rod 13 is respectively connected with pressing plate 11 far from one end of second piston body 26, and one end of pressing plate 11 turns Dynamic to be connected on 2 outside of control box body, the other end is respectively connected with the first spring 12, and first one end of spring 12 far from pressing plate 11 is equal It is fixed on control 2 outer wall of box body, pad 28 of holding one's breath covers each air vent 27, and pad 28 of holding one's breath is in rubber or silica gel material It is a kind of.
When taking Reagent Tube 4, need constantly to press pressing plate 11, pressing plate passes through connecting rod 13 not under the action of the first spring 12 Disconnected that second piston body 26 is driven to move back and forth in gas tube 6, when second piston body 26 is pushed ahead, pad 28 of holding one's breath closing is changed Stomata 27, Non-return air valve 8 are opened, and gas is filled into memotron 3 by Non-return air valve 8, are promoted backward in second piston body 26 When, Non-return air valve 8 is closed, and pad 28 of holding one's breath is separated with 26 surface of second piston body, passes through air vent 27 and the external world inside gas tube 6 Connection, takes a breath, and as the gas of memotron 3 constantly increases, first piston body 18 will be jacked up, and Reagent Tube 4 will as a result, Outside can be by emersion memotron 3, to facilitate the taking-up of experimenter.
When putting Reagent Tube 4, it is only necessary to Reagent Tube 4 is inserted into memotron 3, and be downwardly applied to certain power, make second Spring 29 is compressed, and cylinder 22 moves down under the promotion of sliding bar 20, so that the air discharge duct 25 on cylinder 22 stretches out exhaust 19 outside of pipe, at this point, air discharge duct 25, gas vent 23 make to be in communication with the outside inside memotron 3, realizes 3 internal gas of memotron It is constantly discharged, first piston body 18 moves down, so that Reagent Tube 4 be facilitated to be put into memotron 3.
The foregoing is only a preferred embodiment of the present invention, but scope of protection of the present invention is not limited thereto, Anyone skilled in the art in the technical scope disclosed by the present invention, according to the technique and scheme of the present invention and its Inventive concept is subject to equivalent substitution or change, should be covered by the protection scope of the present invention.

Claims (7)

1. the kit of a kind of CA215 and CA15-3 joint-detection patient with breast cancer, including reagent box body (1), which is characterized in that Several memotrons (3) are equipped with inside the reagent box body (1), it is external to extend reagent box body (1) at the top of each memotron (3) Setting, each memotron (3) bottom are equipped with air inlet pipe (10), and reagent box body (1) bottom is equipped with control box body (2), institute It states control box body (2) interior side and is equipped with gas tube (6) identical with memotron (3) quantity, be equipped on each gas tube (6) Escape pipe (7) is respectively connected with hose (9) on each escape pipe (7), hose (9) far from the one end of escape pipe (7) be both connected into On tracheae (10), hose (9) is equipped with Non-return air valve (8), and reagent box body (1) outer cover is equipped with cover (5), each storage (3) are managed to be arranged through cover (5);
It is equipped with first piston body (18) in each memotron (3), first piston body (18) lower end is equipped with exhaust It manages (19), is equipped with annular flange (24) on the inside of exhaust pipe (19) bottom end, on the axis of the first piston body (18) Through sliding bar (20) are equipped with, several gas vents are equipped on the first piston body (18) and positioned at sliding bar (20) surrounding (23), the top of the sliding bar (20) is equipped with loading plate (21), is all provided between loading plate (21) and first piston body (18) Have second spring (29), the bottom end of the sliding bar (20) is equipped with cylinder (22), and strip row is offered on cylinder (22) Air drain (25), the air discharge duct (25) are respectively positioned on exhaust pipe (19) inside, and cylinder (22) bottom end is respectively positioned on the convex annular In edge (24), and sealing ring is equipped between annular flange (24) and cylinder (22);
Several gas vents (23) are respectively positioned between the exhaust pipe (19) and cylinder (22).
2. the kit of a kind of CA215 according to claim 1 and CA15-3 joint-detection patient with breast cancer, feature exist In loading plate (21) upper surface is arcuate structure, and is equipped with rubber pad in arc, and the diameter of the loading plate (21) is less than The diameter of the memotron (3) is placed with Reagent Tube (4) on the loading plate (21), and the Reagent Tube (4) is located at memotron (3) in, the Reagent Tube (4) is provided with CA215 and CA15-3 association.
3. the kit of a kind of CA215 according to claim 1 and CA15-3 joint-detection patient with breast cancer, feature exist In, it is equipped with second piston body (26) in each gas tube (6), it is several through being equipped on the second piston body (26) Air vent (27), the side that second piston body (26) is located at the escape pipe (7) are equipped with hold one's breath pad (28), second piston body (26) side far from pad (28) of holding one's breath is rotatably connected to connecting rod (13), the one end of connecting rod (13) far from second piston body (26) It is respectively connected with pressing plate (11), one end of the pressing plate (11) is rotatably connected on control box body (2) outside, and the other end is equal It is connected with the first spring (12), the first spring (12) is each attached to control box body (2) outer wall far from the one end of pressing plate (11) On.
4. the kit of a kind of CA215 according to claim 3 and CA15-3 joint-detection patient with breast cancer, feature exist In the pad (28) of holding one's breath covers each air vent (27), and described hold one's breath pad (28) are in rubber or silica gel material It is a kind of.
5. the kit of a kind of CA215 according to claim 1 and CA15-3 joint-detection patient with breast cancer, feature exist In cover (5) inside is equipped with insulating layer (15), is equipped between the cover (5) at the top of the reagent box body (1) close Packing (16).
6. the kit of a kind of CA215 according to claim 1 and CA15-3 joint-detection patient with breast cancer, feature exist In filled with ice cube (17) in the reagent box body (1).
7. the kit of a kind of CA215 according to claim 1 and CA15-3 joint-detection patient with breast cancer, feature exist In equipped with sealing-plug (14) at the top of the memotron (3).
CN201710712573.0A 2017-08-18 2017-08-18 A kind of kit of CA215 and CA15-3 joint-detection patient with breast cancer Active CN107515306B (en)

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