CN107271315B - A kind of dressing penetrates the ability test method of vapor - Google Patents
A kind of dressing penetrates the ability test method of vapor Download PDFInfo
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- CN107271315B CN107271315B CN201710438050.1A CN201710438050A CN107271315B CN 107271315 B CN107271315 B CN 107271315B CN 201710438050 A CN201710438050 A CN 201710438050A CN 107271315 B CN107271315 B CN 107271315B
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N5/00—Analysing materials by weighing, e.g. weighing small particles separated from a gas or liquid
- G01N5/02—Analysing materials by weighing, e.g. weighing small particles separated from a gas or liquid by absorbing or adsorbing components of a material and determining change of weight of the adsorbent, e.g. determining moisture content
- G01N5/025—Analysing materials by weighing, e.g. weighing small particles separated from a gas or liquid by absorbing or adsorbing components of a material and determining change of weight of the adsorbent, e.g. determining moisture content for determining moisture content
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Abstract
A kind of dressing penetrates the ability test method of vapor, dressing container is the ability wound model that dressing penetrates vapor, dressing has transparent shell through the ability wound model of vapor, transparent shell is equipped with lid, lid middle part successively opens up slot, sponge slot and through-hole, and slot, sponge slot and through-hole communicate, and through-hole is communicated with the liquid storage chamber of transparent shell, it is opened up on lid side wall into pin hole, enters pin hole and communicated with sponge slot.The quality that dressing absorbs liquid can be tested out simultaneously through the design of the ability wound model of vapor by dressing, medically correctly to be selected the liquid controlling of different dressing.
Description
Technical field
The present invention, which relates to, belongs to medical device product quality inspection field, is exactly the energy that a kind of dressing penetrates vapor
Power test method.
Background technique
It is an important composition portion for treating device product quality inspection to the inspection that dressing penetrates the ability performance of vapor
Point, but presently, there are following problems: environment temperature locating for the patient using dressing and relative humidity difference, the surface of a wound portion of patient
Position is different, how much equal also differences of the ingredient of wound fluid and its amount.The same surface of a wound of even same position patient, not
The ingredient and its amount of wound fluid of the same period are also different.It therefore, must if thinking the liquid controlling of comparative evaluation's difference dressing
A unified test platform must be established, including identical test model, unified temperature and humidity environment, identical position, identical
Surface of a wound simulated solution, identical exudation flow quantity etc..
Summary of the invention
To solve the above problems, the object of the present invention is to provide a kind of ability test methods that dressing penetrates vapor.
The present invention to achieve the above object, is achieved through the following technical solutions:
A kind of dressing penetrates the ability test method of vapor, comprising the following steps:
1. preparing an experiment casing (1), chamber door is set in the front of experiment casing (1), the top peace in experiment casing (1)
It fills fan (2), lower clapboard (6) and upper spacer (9) is fixedly mounted in experiment casing (1), the left and right ends installation on lower clapboard (6)
Heater (7) are installed respectively, Temperature Humidity Sensor (4) are installed at the middle part of lower clapboard (6), peace of uniformly arranging on lower clapboard (6)
It fills electronic scale (5), a dressing container is placed on each electronic scale (5), the lower part of lower clapboard (6) connects control circuit board, control
Circuit board processed is electrically connected with fan (2), heater (7), Temperature Humidity Sensor (4) and electronic scale (5) respectively, on upper spacer (9)
It is fixedly mounted pallet (10), is placed with glycerine water solution in pallet (10), the experiment casing (1) is double-door type, described
Heater (7) is incandescent lamp, and the dressing container connects liquid dispensing apparatus (11), and liquid dispensing apparatus (11) is used for defeated to dressing container
Enter surface of a wound simulated solution；
2. opening chamber door, dressing is put in dressing container, closes chamber door, is opened fan (2) and heater (7), will be tried
Temperature control in tryoff body (1) is at 36.5 ~ 37.5 DEG C, and relative humidity control is 39% ~ 41%, the use of Temperature Humidity Sensor (4)
Temperature and humidity in detection experiment casing (1), and the data are passed into fan (2) and heater (7) by control circuit board,
Humidity is adjusted by fan (2) forced convertion, adjusts the temperature in experiment casing (1) by heater (7)；
3. continuing fluid injection into dressing container by liquid dispensing apparatus (11), to each dressing container infusion within the fluid injection time
The quality of liquid is m1, the increased quality of dressing container is m on each electronic scale (5)2, evaporation capacity m can be calculated3, evaporation capacity
m3Calculation formula be m3=m1-m2。
Preferably, dressing container is the ability wound model that dressing penetrates vapor, and dressing can be made every effort to achieve through vapor
Surface model has transparent shell (18), and transparent shell (18) is equipped with lid (20), successively opens up slot (27), sponge slot in the middle part of lid (20)
(26) it is communicated with through-hole (25), slot (27), sponge slot (26) and through-hole (25), the liquid storage chamber of through-hole (25) and transparent shell (18)
(8) it communicates, covers on (20) side wall and open up into pin hole (23), enter pin hole (23) and communicated with sponge slot (26), sponge slot (26) is built-in
There are sponge (17), enter pin hole (23) and be provided with injection needle (13), injection needle (13) is pierced into sponge slot (26), is installed on lid (20)
Annular slab (24), lid (20) are fixed by fixing screws (16) and annular slab (24)；
When penetrating the ability wound model of vapor using dressing, first fixing screws (16) are unscrewed, after lid (20) is opened
Dressing (19) is placed between lid (20) and annular slab (24), it is then fixed with fixing screws (16), pass through injection needle (13)
Continue fluid injection into sponge slot (26), dressing (19) volatilizees absorbed when absorbing the surface of a wound simulated solution in sponge slot on sponge
Liquid, extra liquid forms product by the liquid storage chamber (8) that through-hole (25) flow into transparent shell (18) after dressing (19) saturation
Liquid.
Preferably, liquid dispensing apparatus (11) is infusion pump or electronic pump, and liquid dispensing apparatus (11) passes through perfusion tube and injection needle
(13) it connects.
Preferably, temperature controller (3) are equipped on the outside of the experiment casing (1), temperature controller (3) is electrically connected with control circuit board.
The present invention has the advantages that
The experiment casing that the present invention passes through constant temperature and humidity is that the Liquid absorption test of dressing creates optimal detection environment,
Effective supervision and the tune of testing dressing environment may be implemented test method of the invention by the data of the Temperature and Humidity module on circuit board
It is whole, evaporation capacity can be directly calculated by increasing quality in reduction amount in liquid dispensing apparatus and each electronic scale, step is few, is convenient for
Operation, and the test can carry out parallel test simultaneously, and effectively saving test period, reduction test error improve measuring accuracy；
Preferred embodiments of the present invention can be tested out by dressing through the design of the ability wound model of vapor deposited simultaneously
Material absorbs the quality of liquid, medically correctly to be selected the liquid controlling of different dressing.It also sets simultaneously
Two kinds of external wound models of level body position and vertical position are set, respectively from two angles of water vapour permeability and retention time
To evaluate dressing in high diffusate to the controlling of wound fluid.
Detailed description of the invention
Fig. 1 is structural schematic diagram of the dressing of the present invention through the ability test system of vapor；Fig. 2 is experiment casing structure
Schematic diagram；Fig. 3 is Fig. 2 top view；Fig. 4 is level body position model example；Fig. 5 is vertical postural test model example；Fig. 6 is figure
5 left views.
Appended drawing reference: 1 experiment casing, 2 fan, 3 temperature controller, 4 Temperature Humidity Sensor, 5 electronic scale, 6 lower clapboard 7 heating
12 hole of device 8 chamber, 9 upper spacer, 10 pallet, 11 liquid dispensing apparatus, 13 injection needle, 14 gas vent, 15 hydrops, 16 fixing screws 17
It is logical that 21 bracket of water-absorbing sponge 18 transparent shell, 19 dressing, 20 annular holder, 22 computer 23 enters 24 annular slab 25 of pin hole
26 sponge slot, 27 slot 28 perfusion tube in hole enters hole.
Specific embodiment
Dressing of the present invention penetrates the ability test system of vapor, as shown in Figure 1, including experiment casing (1), packet
The front setting chamber door of experiment casing (1) is included, the intracorporal top of chamber is equipped with fan (2).It is fixed in experiment casing (1)
Lower clapboard (6) and upper spacer (9).Lower clapboard (6) is equipped with heater (7), Temperature Humidity Sensor (4) and electronic scale (5).Electronics
Scale (5) is equipped with dressing container, and the dressing container can be the container of common disk or bowl.The lower part of lower clapboard (6) is equipped with
Control circuit board, control circuit board are electrically connected with fan (2), heater (7), Temperature Humidity Sensor (4) and electronic scale (5) respectively
It connects.Control circuit board can receive data information and each electric component work of control of Temperature Humidity Sensor (4) and electronic scale (5).
The control circuit board can be made of the existing chip for having corresponding function and circuit board.Upper spacer is fixed with support on (9)
Disk (10).For the intracorporal humidity of Control experiment cabinet (1) case.It is placed with glycerine water solution in pallet (10), it is strong by fan (2)
Convection current processed, which is realized, adjusts relative humidity.The Temperature Humidity Sensor (4) can be pt100 temperature sensor, only detect temperature.It is described
Syringe (13) can be 6% Rule cone joint.Temperature controller (3) can be the control panel with display.
For to the operation on an electronic scale, when detection, opens chamber door and be placed in the container for filling dressing (19)
On electronic scale (5), chamber door is closed；After adjusting the temperature and humidity in case, typical temperature control is at 37 degree, relative humidity 40%, and
Fluid injection is continued on dressing (19) by electronic pump or infusion pump afterwards, for example the fluid injection time is 1 hour reservoir quantity m1=0.5g, if
Electronic scale (5) second must fill the container weight gain m of dressing (19) after fluid injection one hour2=0.3g, then evaporation capacity m3=m1-m2=0.2g。
Since the placement location of dressing (19) will have a direct impact on the effect of dressing (19) evaporation, it is deposited accurately to measure
Expect the evaporation capacity of (19), design following scheme: as shown in Figures 3 to 5, the dressing container is the energy that dressing penetrates vapor
Make every effort to achieve surface model.Dressing has transparent shell (18) through the ability wound model of vapor, and transparent shell (18) is equipped with lid (20).
Slot (27), sponge slot (26) and through-hole (25), slot (27), sponge slot (26) and through-hole (25) phase are successively opened up in the middle part of lid (20)
It is logical.Through-hole (25) is communicated with the liquid storage chamber (8) of transparent shell (18).It opens up on lid (20) side wall into pin hole (23), enters pin hole
(23) it is communicated with sponge slot (26).Sponge slot (26) is provided with sponge (17), enters pin hole (23) and is provided with injection needle (13), injection
Needle (13) is pierced into sponge slot (26).It covers on (20) and annular slab (24) is installed, lid (20) passes through fixing screws (16) and annular slab
(24) fixed.In use, dressing (19) is fixed between lid (20) and annular slab (24) as shown in Figure 1, can as needed by
Dressing (19) is horizontal or is vertically placed on electronic scale (5).When vertical placement, mountable bracket 21 below transparent shell (18).
The liquid dispensing apparatus (11) of surface of a wound simulated solution can be continued to penetrate water to dressing by certain rate by perfusion tube and injection needle (13)
Dressing (19) on the ability wound model of steam is transfused simulated solution.In ability wound model of the dressing through vapor, apply
Material can evaporate a part of absorbed liquid when absorbing simulated solution.After dressing saturation, extra liquid meeting flow model
In transparent shell (18) and form hydrops (15).Electronic scale (5) can weigh the examination of feed liquid body controlling according to certain sampling interval
It tests the quality of model and is transferred in computer (22).
For surface of a wound simulated solution by the solution composition of sodium chloride and calcium chloride, which is containing 142 mmol/L sodium ions and 2.5
The calcium ion of mmol/L.The ion concentration of the solution is equivalent to human serum or wound fluid.Deionization is used in volumetric flask
Water dissolves 8.298 g sodium chloride and 0.368 g calcium chloride dihydrate and is diluted to 1 L.
Dressing when level is put penetrates the ability wound model of vapor as shown in figure 4, injection needle (13) and surface of a wound mould
Liquid dispensing apparatus (11) connection of quasi- liquid, simulated solution will be persistently conveyed to water-absorbing sponge (17) with certain rate.It is fixed on
The dressing of side can also evaporate the liquid that a part has absorbed while absorbing the liquid sucked in sponge.When dressing (19)
After saturation, the inner extra liquid of water-absorbing sponge (17) can flow into transparent shell (18) and form hydrops (15).Vertically put
Dressing is as shown in Figure 5 and Figure 6 through the ability wound model of vapor, can be into when being put with dedicated bracket (21) for pedestal
The test of the vertical position of row, it is same that test principle with level puts phase.
The surface of a wound simulated solution liquid dispensing apparatus (11) is infusion pump or electronic pump, and infusion pump or electronic pump are to provide
The flow of 0.5g/h, accuracy are positive and negative 3%.
In order to be easier the anti-ability wound model set dressing and penetrate vapor, the experiment casing (1) can be list
It opens the door, double-door type preferably as depicted in figs. 1 and 2 or clamshell doors.
In order to facilitate the adjusting intracorporal temperature of experiment casing, while simplifying whole structure, reducing cost, as shown in Figure 1,
The heater (7) is incandescent lamp.
Technical solution of the present invention is not restricted in the range of embodiment of the present invention.The not detailed description of the present invention
Technology contents be well-known technique.
Claims (3)
1. a kind of ability test method that dressing penetrates vapor, it is characterised in that: the following steps are included:
1. preparing an experiment casing (1), chamber door is set in the front of experiment casing (1), wind is installed on the top in experiment casing (1)
It fans (2), lower clapboard (6) and upper spacer (9) is fixedly mounted in experiment casing (1), difference is installed in the left and right ends on lower clapboard (6)
It installs heater (7), Temperature Humidity Sensor (4) are installed at the middle part of lower clapboard (6), installation electricity of uniformly arranging on lower clapboard (6)
Sub- scale (5), a dressing container is placed on each electronic scale (5), and the lower part of lower clapboard (6) connects control circuit board, control electricity
Road plate is electrically connected with fan (2), heater (7), Temperature Humidity Sensor (4) and electronic scale (5) respectively, fixed on upper spacer (9)
It installs pallet (10), is placed with glycerine water solution in pallet (10), the experiment casing (1) is double-door type, the heating
Device (7) is incandescent lamp, and the dressing container connects liquid dispensing apparatus (11), and liquid dispensing apparatus (11) is used to input to dressing container and create
Face simulated solution；
2. opening chamber door, dressing is put in dressing container, closes chamber door, fan (2) and heater (7) is opened, by chamber
Temperature control in body (1) is at 36.5~37.5 DEG C, and relative humidity control is 39%~41%, the use of Temperature Humidity Sensor (4)
Temperature and humidity in detection experiment casing (1), and the data are passed into fan (2) and heater (7) by control circuit board,
Humidity is adjusted by fan (2) forced convertion, adjusts the temperature in experiment casing (1) by heater (7)；
3. continuing fluid injection into dressing container by liquid dispensing apparatus (11), to each dressing container infusion liquid within the fluid injection time
Quality be m1, the increased quality of dressing container is m on each electronic scale (5)2, evaporation capacity m can be calculated3, evaporation capacity m3's
Calculation formula is m3=m1-m2, to measure the ability that tested dressing penetrates vapor；
The dressing container is the ability wound model that dressing penetrates vapor, and dressing has through the ability wound model of vapor
Transparent shell (18), transparent shell (18) are equipped with lid (20), successively open up slot (27), sponge slot (26) and through-hole in the middle part of lid (20)
(25), slot (27), sponge slot (26) and through-hole (25) communicate, and through-hole (25) is communicated with the liquid storage chamber (8) of transparent shell (18), lid
(20) it being opened up on side wall into pin hole (23), enters pin hole (23) and communicated with sponge slot (26), sponge slot (26) is provided with sponge (17),
Entering pin hole (23) to be provided with injection needle (13), injection needle (13) is pierced into sponge slot (26), annular slab (24) are installed on lid (20),
It is fixed by fixing screws (16) and annular slab (24) to cover (20)；
When penetrating the ability wound model of vapor using dressing, first fixing screws (16) are unscrewed, lid (20) will apply after opening
Material (19) is placed between lid (20) and annular slab (24), fixing screws (16) fixation is then used, by injection needle (13) to sea
Continue fluid injection in continuous slot (26), dressing (19) volatilizees absorbed liquid when absorbing the surface of a wound simulated solution in sponge slot on sponge
Body, extra liquid forms hydrops by the liquid storage chamber (8) that through-hole (25) flow into transparent shell (18) after dressing (19) saturation.
2. the ability test method that a kind of dressing according to claim 1 penetrates vapor, it is characterised in that: filled to liquid
Setting (11) is infusion pump or electronic pump, and liquid dispensing apparatus (11) is connect by perfusion tube with injection needle (13).
3. the ability test method that a kind of dressing according to claim 1 penetrates vapor, it is characterised in that: the examination
Temperature controller (3) are equipped on the outside of tryoff body (1), temperature controller (3) is electrically connected with control circuit board.
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| CN201710438050.1A CN107271315B (en) | 2017-06-06 | 2017-06-06 | A kind of dressing penetrates the ability test method of vapor |
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| CN201710438050.1A CN107271315B (en) | 2017-06-06 | 2017-06-06 | A kind of dressing penetrates the ability test method of vapor |
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| CN107271315B true CN107271315B (en) | 2019-05-28 |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN108896426B (en) * | 2018-05-10 | 2020-10-13 | 山东省医疗器械产品质量检验中心 | System and method for evaluating hemostatic performance of dressing in vitro |
| CN108592986A (en) * | 2018-05-10 | 2018-09-28 | 山东省医疗器械产品质量检验中心 | The unimpeded verifying attachment of micropore needle tubing and dressing anthemorrhagic performance in-vitro evaluation system and method |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3638478A (en) * | 1969-10-06 | 1972-02-01 | Dietert Co Harry W | Structure for sand testing |
| US3965724A (en) * | 1974-12-06 | 1976-06-29 | Ambrose Wallace R | Device and method for calculating temperature and water vapor pressure |
| CN1013328B (en) * | 1988-07-14 | 1991-07-24 | 中国科学院半导体研究所 | Technique and apparatus for filming on micro-area |
| US4862730A (en) * | 1988-10-03 | 1989-09-05 | W. L. Gore & Associates, Inc. | Test method for determination of moisture vapor transmission rate |
| WO1999066306A1 (en) * | 1998-06-15 | 1999-12-23 | The United States Of America | Apparatus and method for determining transport properties of porous materials |
| ATE366301T1 (en) * | 2001-02-05 | 2007-07-15 | Millipore Corp | DETECTION OF MICROORGANISMS |
| CN100575916C (en) * | 2005-12-26 | 2009-12-30 | 比亚迪股份有限公司 | A kind of method of measuring dressing strength of battery electrode flake |
| WO2009041632A1 (en) * | 2007-09-28 | 2009-04-02 | Ulvac, Inc. | Device for measuring steam permeability, and method for the device |
| AU2008351108A1 (en) * | 2008-02-21 | 2009-08-27 | Teikoku Seiyaku Co., Ltd. | Apparatus for environmental simulation measurement of wound coating material on the skin and measurement method therefor |
| CN101581658A (en) * | 2008-05-16 | 2009-11-18 | 比亚迪股份有限公司 | Method for measuring bonding strength of granules of pole piece active material layer |
| CN101487783B (en) * | 2009-02-24 | 2011-06-15 | 天津工业大学 | Test device and method for fabric moisture permeability |
| CN101788441B (en) * | 2009-12-30 | 2011-06-15 | 首钢总公司 | Device and method for determining moisture content and size composition of sinter mixture |
| CN203824877U (en) * | 2013-07-15 | 2014-09-10 | 江苏华科塑业有限公司 | Membrane venting and permeability detector |
| CN105087360B (en) * | 2015-09-06 | 2017-06-06 | 山东省医疗器械产品质量检验中心 | A kind of external wound model and its application method |
| CN105954141B (en) * | 2016-06-24 | 2018-11-06 | 湖南康程护理用品有限公司 | A kind of paper diaper gas permeability detecting system and method |
| CN106053120B (en) * | 2016-08-09 | 2018-06-01 | 山东省医疗器械产品质量检验中心 | Pinpoint accuracy heat moisture exchanger moisture loss tester and its method of work |
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